52 results found.

AIDS Associated Nephropathy, Focal Glomerulosclerosis, or HIV Inf Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Genetic Markers for Focal Segmental Glomerulosclerosis.

HIV Infections Clinical Trial using Current ARV medications; Current TB medications; Current hormonal contraceptive medications

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting N/A or older.
- Pharmacokinetic Properties of Antiretroviral and Related Drugs During Pregnancy and Postpartum.
Current ARV medications; Current TB medications; Current hormonal contraceptive medications

Kaposi's Sarcoma, HIV+, HIV Positive, or AIDS Clinical Trial using aldoxorubicin

CytRx - Recruiting 18 years or older.
- An Open-Label Pilot Phase 2 Study to Investigate Efficacy, Safety, and Intratumoral Kinetics of ALDOXORUBICIN in HIV-Infected Patients With Kaposi's Sarcoma.
aldoxorubicin

HIV Infections Clinical Trial using Methotrexate (MTX); Placebo; Folic acid

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 40 years or older.
- Effect of Reducing Inflammation With Low Dose Methotrexate on Inflammatory Markers and Endothelial Function in Treated and Suppressed HIV Infection.
Methotrexate (MTX); Placebo; Folic acid

Tuberculosis, or HIV Infections Clinical Trial using Rifapentine (RPT); Isoniazid (INH); Pyridoxine (Vitamin B6)

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 13 years or older.
- Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection.
Rifapentine (RPT); Isoniazid (INH); Pyridoxine (Vitamin B6)

HIV Infections Clinical Trial using Dolutegravir (DTG) tablet formulation; DTG oral pediatric granules taken as suspension or granules

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting N/A to 17 years.
- Phase I/II, Multi-Center, Open-Label Pharmacokinetic, Safety, Tolerability and Antiviral Activity of GSK1349572, a Novel Integrase Inhibitor, in Combination Regimens in HIV-1 Infected Infants, Children and Adolescents.
Dolutegravir (DTG) tablet formulation; DTG oral pediatric granules taken as suspension or granules

HIV Infection, or Unspecified Adult Solid Tumor, Protocol Specifi Clinical Trial using cabozantinib-s-malate; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase I Trial of Cabozantinib (XL184) for Advanced Solid Tumors in Persons With HIV Infection.
cabozantinib-s-malate; pharmacological study; laboratory biomarker analysis

HIV-1, HIV Infections, or Acquired Immunodeficiency Syndrome Clinical Trial using E/C/F/TAF; DRV; Pre-existing ARV regimen

Gilead Sciences - Recruiting 18 years or older.
- A Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults.
E/C/F/TAF; DRV; Pre-existing ARV regimen

HIV Infection Clinical Trial using Maraviroc; Emtricitabine; Tenofovir disoproxil fumarate; Maraviroc placebo; Emtricitabine placebo; Tenofovir disoproxil fumarate placebo

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 18 years or older.
- A Phase II Randomized, Double-Blind, Study of the Safety and Tolerability of Maraviroc (MVC), Maraviroc + Emtricitabine (MVC+FTC), Maraviroc + Tenofovir Disoproxil Fumarate (MVC+TDF), or Tenofovir Disoproxil Fumarate + Emtricitabine (TDF+FTC) For Pre-Exposure Prophylaxis (PrEP) To Prevent HIV Transmission in At-Risk Men Who Have Sex With Men and in At-Risk Women.
Maraviroc; Emtricitabine; Tenofovir disoproxil fumarate; Maraviroc placebo; Emtricitabine placebo; Tenofovir disoproxil fumarate placebo

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using E/C/F/TAF

Gilead Sciences - Recruiting 12 years to 17 years.
- A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents.
E/C/F/TAF

Musculoskeletal Diseases Clinical Trial using Multimedia Patient Decision Aids (MM-PtDAs); Comparative Effectiveness Research Summary Guide (CERSG); Questionnaires

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- IADAPT-Third Phase.
Multimedia Patient Decision Aids (MM-PtDAs); Comparative Effectiveness Research Summary Guide (CERSG); Questionnaires

HIV, or AIDS Clinical Trial using individualized Texting for Adherence Building (iTAB); Psychoeducation

University of California, San Diego - Recruiting 18 years or older.
- Personalized Text Messages to Improve ART Adherence in HIV+ Methamphetamine Users.
individualized Texting for Adherence Building (iTAB); Psychoeducation

Anal Cancer, Nonneoplastic Condition, Penile Cancer, or Precancer Clinical Trial using quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine; laboratory biomarker analysis

AIDS Malignancy Clinical Trials Consortium - Recruiting 13 years to 26 years.
- AMC-072: Protective Effect of Quadrivalent Vaccine in Young HIV-Positive Males Who Have Sex With Males.
quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine; laboratory biomarker analysis

HIV Infections Clinical Trial using 'Kallunk oxide (Immunotherapy) '

Traditional Alternative Medicine Research, India - Recruiting 8 years to 45 years.
- Phase III Clinical Studies on Traditional CAM Therapy in the Treatment of HIV/AIDS.
'Kallunk oxide (Immunotherapy) '

HIV Infections, AIDS, or Opportunistic Infections Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infection.

Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficie Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 14 years or older.
- Characterization and Management of Patients With HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy.

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using Elvitegravir; RTV-boosted PI

Gilead Sciences - Recruiting N/A to 17 years.
- A Phase 2/3 Multicenter, Open-Label, Multicohort, Two-Part Study Evaluating the Pharmacokinetics (PK), Safety, and Antiviral Activity of Elvitegravir (EVG)Administered With a Background-Regimen (BR) Containing a Ritonavir-Boosted Protease Inhibitor (PI/r) in HIV-1 Infected, Antiretroviral Treatment-Experienced Pediatric Subjects.
Elvitegravir; RTV-boosted PI

AIDS Clinical Trial using Blood collection; GSK HIV vaccine 732462

GlaxoSmithKline - Recruiting 18 years to 56 years.
- Long-term Follow-up of Participants From Studies Evaluating the HIV Vaccine 732462.
Blood collection; GSK HIV vaccine 732462

HIV Infection Clinical Trial using Hydroxychloroquine

St Stephens Aids Trust - Recruiting 18 years to 65 years.
- The Immunological Impact of Adding Hydroxychloroquine in Patients With Discordant CD4+ Cell Responses to Suppressive HAART: A Phase I Pilot Study..
Hydroxychloroquine

Hepatitis B Virus, or HIV Clinical Trial using Standard of care

University of North Carolina, Chapel Hill - Recruiting 18 years or older.
- CIDRZ-1220 Antiretroviral Treatment Outcomes in HIV-HBV Co-infected Patients in Southern Africa: a Collaborative Multi-country Prospective Cohort Analysis for International Epidemiologic Databases to Evaluate AIDS- Southern Africa (HIV/HBV-coinfection in IeDEA-SA).
Standard of care

Influenza Clinical Trial using Amantadine, Ribavirin, Oseltamivir; Oseltamivir

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 18 years or older.
- A Randomized Double-Blind Phase 2 Study Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications.
Amantadine, Ribavirin, Oseltamivir; Oseltamivir

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using ATV; DRV; Cobicistat; Background regimen

Gilead Sciences - Recruiting 3 Months to 17 years.
- A Phase 2/3, Multicenter, Open-label, Multicohort, Two-Part Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co), Administered With Background Regimen (BR) in HIV-1 Infected, Treatment-Experienced, Virologically Suppressed Pediatric Subjects.
ATV; DRV; Cobicistat; Background regimen

Human Immunodeficiency Virus (HIV), or Acquired Immune Deficiency Clinical Trial

Columbia University - Recruiting 1 Month to 12 years.
- Enhanced Surveillance and 2 Year Outcomes of Children Enrolled on Antiretroviral Therapy (ART) in Public Health Facilities in the Eastern Cape Province, South Africa.

Adult Grade III Lymphomatoid Granulomatosis, AIDS-related Diffuse Clinical Trial using doxorubicin hydrochloride; vincristine sulfate; vorinostat; prednisone; rituximab; cyclophosphamide; etoposide; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Sequential Phase I/Randomized Phase II Trial of Vorinostat and Risk-Adapted Chemotherapy With Rituximab in HIV-Related B-cell Non-Hodgkin's Lymphoma.
doxorubicin hydrochloride; vincristine sulfate; vorinostat; prednisone; rituximab; cyclophosphamide; etoposide; laboratory biomarker analysis; pharmacological study

HIV/AIDS Clinical Trial using omega 3 fatty acids

Coordinaci¢n de Investigaci¢n en Salud, Mexico - Recruiting 20 years to 60 years.
- Effect of Omega 3 Fatty Acids on Oxidative Stress in Seropositive HIV Patients.
omega 3 fatty acids

Influenza, Human Clinical Trial using Oseltamivir; Oseltamivir Placebo

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 18 years to 64 years.
- A Randomized Double-Blind Study Comparing Oseltamivir Versus Placebo for the Treatment of Influenza in Low Risk Adults.
Oseltamivir; Oseltamivir Placebo

HIV-1 Infection Clinical Trial

Gen-Probe, Incorporated - Recruiting 15 years or older.
- Collection of Plasma Samples From Human Immunodeficiency Virus (HIV) Type 1 (HIV-1) Infected Individuals for the Clinical Evaluation of the Aptima HIV-1 Quant Dx Assay.

Acquired Immunodeficiency Syndrome, or HIV Infections Clinical Trial using EVG/COBI/FTC/TDF

Gilead Sciences - Recruiting 12 years to 17 years.
- A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/ Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents.
EVG/COBI/FTC/TDF

HIV, or ART Clinical Trial using Comprehensive intervention group

National Center for AIDS/STD Control and Prevention, China CDC - Recruiting 18 years to 59 years.
- A Cluster-randomized Controlled Trial of Promoting Antiretroviral Therapy Among Serodiscordant Couples to Reduce HIV Transmission.
Comprehensive intervention group

Anal Cancer, HIV Infection, or Human Papilloma Virus Infection Clinical Trial using comparison of screening methods; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

AIDS Malignancy Clinical Trials Consortium - Recruiting 18 years or older.
- Screening HIV-Infected Women for Anal Cancer Precursors.
comparison of screening methods; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

HIV-1 Infection Clinical Trial using Placebos of GTU-multiHIV B and LIPO-5 vaccines; GTU-multHIV B vaccine and LIPO-5 vaccine

French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) - Recruiting 18 years to 59 years.
- Evaluation of a Therapeutic Immunization Strategy Associating a DNA Vaccine (GTU-MultiHIV B) Followed by a Lipopeptide Vaccine (LIPO-5) in the Control of Viral Replication Following Antiretroviral Treatment Interruption in HIV-1 Infected Patients With a CD4 Cell Count ò 600/mm3.
Placebos of GTU-multiHIV B and LIPO-5 vaccines; GTU-multHIV B vaccine and LIPO-5 vaccine

HIV Infection Clinical Trial using adherence reinforcement; Antiretroviral Therapy Darunavir/r + Raltegravir + 2 NRTIs (as chosen by the investigators)

French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) - Recruiting 18 years or older.
- Systematic 'Adherence Intervention' Phase Before Switching to 3rd-line ART in Patients With 2nd-line ART Virologic Failure in Sub-Saharan Africa : a Phase 2b Non-randomized Study..
adherence reinforcement; Antiretroviral Therapy Darunavir/r + Raltegravir + 2 NRTIs (as chosen by the investigators)

Human Immunodeficiency Virus (HIV), or Acquired Immune Deficiency Clinical Trial using HIV Self-testing with Standard Counseling and Testing (SCT) Confirmation

Columbia University - Recruiting 18 years or older.
- Enhanced HIV Prevention in Serodiscordant Couples Study #3: Feasibility of Home-based Partner Self Testing for HIV.
HIV Self-testing with Standard Counseling and Testing (SCT) Confirmation

HIV-1 Infection, or Pf Subclinical Parasitemia Clinical Trial using Lopinavir/ritonavir; Emtricitabine/tenofovir disoproxil fumarate; Efavirenz; Nevirapine; emtricitabine/tenofovir disoproxil fumarate; trimethoprim/sulfamethoxazole

AIDS Clinical Trials Group - Recruiting 18 years or older.
- An Open-Label, Proof of Concept, Randomized Trial Comparing a LPV/r-Based to an nNRTI-Based Antiretroviral Therapy Regimen for Clearance of Plasmodium Falciparum Subclinical Parasitemia in HIV-infected Adults With CD4+ Counts >200 and <350 Cells/mm3.
Lopinavir/ritonavir; Emtricitabine/tenofovir disoproxil fumarate; Efavirenz; Nevirapine; emtricitabine/tenofovir disoproxil fumarate; trimethoprim/sulfamethoxazole

AIDS-Related Primary Central Nervous System Lymphoma, or HIV Clinical Trial using Methotrexate; rituximab; antiviral therapy; leucovorin calcium

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- AIDS-Related Primary Central Nervous System Lymphoma: A Phase II Pilot Study of High-Dose Intravenous Methotrexate With Rituximab Leucovorin Rescue and Highly Active Antiretroviral Therapy.
Methotrexate; rituximab; antiviral therapy; leucovorin calcium

HIV Clinical Trial using Community leader engagement; Community days; Community Peer Groups

Elizabeth Glaser Pediatric AIDS Foundation - Recruiting 18 years or older.
- Advancing Community Level Action for Improving MCH/PMTCT.
Community leader engagement; Community days; Community Peer Groups

Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymph Clinical Trial using leukapheresis; allogeneic hematopoietic stem cell transplantation; autologous hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; laboratory biomarker analysis; DNA analysis; RNA analysis; flow cytometry; reverse transcriptase-polymerase chain reaction; nucleic acid sequencing; protein expression analysis

Fred Hutchinson Cancer Research Center - Recruiting N/A to 75 years.
- Human Immunodeficiency Virus (HIV)-Specific Immune Reconstitution After Hematopoietic Cell Transplant for Treatment of Hematologic Malignancy in Patients Infected With HIV.
leukapheresis; allogeneic hematopoietic stem cell transplantation; autologous hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; laboratory biomarker analysis; DNA analysis; RNA analysis; flow cytometry; reverse transcriptase-polymerase chain reaction; nucleic acid sequencing; protein expression analysis

HIV/AIDS Clinical Trial using Study Intervention for Retention (APFU)

Columbia University - Recruiting 16 years or older.
- Mother Infant Retention for Health: Evaluation of a Multicomponent Strategy to Link and Retain Newly Identified HIV-infected Pregnant Women and Their Infants Throughout the Antenatal and Post-partum Period.
Study Intervention for Retention (APFU)

HIV, or AIDS Clinical Trial

George Washington University - Recruiting N/A or older.
- Development of a City-Wide Cohort of HIV-Infected Persons in Care in the District of Columbia: The DC Cohort.

HIV Infections Clinical Trial using SeV-G(NP) (0.2mL, 2x10^7 CIU); SeV-G(NP) (0.2mL, 2x10^8 CIU); Ad35-GRIN (0.5mL)

International AIDS Vaccine Initiative - Recruiting 18 years to 50 years.
- A Phase I Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Trial to Evaluate the Safety and Immunogenicity of a Sendai HIV Vaccine SeV-G(NP) Given Intranasally and Ad35-GRIN Administered Intramuscularly in Prime-Boost Regimens in HIV-Uninfected, Healthy Adult Volunteers.
SeV-G(NP) (0.2mL, 2x10^7 CIU); SeV-G(NP) (0.2mL, 2x10^8 CIU); Ad35-GRIN (0.5mL)

HIV-2 Infection Clinical Trial using emtricitabine / tenofovir disoproxil fumarate / raltegravir .

French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) - Recruiting 18 years or older.
- ANRS 159 VIH-2 : Trial Evaluating a First Line Combination Therapy With Raltegravir, Emtricitabine and Tenofovir in HIV-2 Infected Patients.
emtricitabine / tenofovir disoproxil fumarate / raltegravir .

HIV, Tuberculosis, or Pediatric Clinical Trial using Development of a diagnosis algorithm

French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) - Recruiting N/A to 13 years.
- Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam) and Africa (Burkina Faso, Cameroon) ANRS 12229 PAANTHER 01 (Pediatric Asian African Network for Tuberculosis and HIV Research).
Development of a diagnosis algorithm

Moderate or Severe Vision Impairment, Both Eyes Clinical Trial using portable electronic magnifier; optical aids

Central Manchester University Hospitals NHS Foundation Trust - Recruiting 18 years to 95 years.
- The Effectiveness of Portable Electronic Vision Enhancement Systems (EVES) in Comparison to Optical Magnifiers for Near Vision Activities in Visual Impairment - The p-EVES Study.
portable electronic magnifier; optical aids

HIV Disease Clinical Trial using à1 Proteinase Inhibitor; Placebo

AIDS Community Research Initiative of America - Recruiting 18 years to 65 years.
- A Double Blind, Randomized Trial to Evaluate the Safety and Efficacy of 8 Weekly Doses of Prolastinr-C (à1Proteinase Inhibitor, à1PI) in Human Immunodeficiency Virus-Infected Subjects Who Are 18 to 65 Years of Age and Who Are on Antiretroviral Therapy.
à1 Proteinase Inhibitor; Placebo

HIV, AIDS, Opioid Dependence, or Drug Dependence Clinical Trial using Depot Naltrexone

Yale University - Recruiting 18 years or older.
- Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populations.
Depot Naltrexone

Rectal Health, Rectal Behaviors, or Anorectal Symptomatology Clinical Trial

University of California, Los Angeles - Recruiting 18 years or older.
- Rectal Health, Behaviors and Microbicide Acceptability.

HIV Infection, or AIDS Clinical Trial using once daily minimum 3-drug regimen of anti-retroviral medications

407 Doctors - Recruiting 18 years or older.
- A Randomised, Multi-Centre, Open-Label Study in Well-Controlled Treatment-Experienced HIV-Infected Patients to Assess Compliance With a Once-Daily Regimen of Lamivudine, Efavirenz and Didanosine Versus Continuation of Current Anti-Retroviral Regimen Delivered at Least Twice Daily.
once daily minimum 3-drug regimen of anti-retroviral medications