9 results found.

Recurrent Glioblastoma Clinical Trial using Nivolumab; Ipilimumab; Bevacizumab

Bristol-Myers Squibb - Recruiting 18 years or older.
- A Randomized Phase IIb, Open Label Study of Nivolumab or Nivolumab in Combination With Ipilimumab Versus Bevacizumab in Adult Subjects With Recurrent Glioblastoma (GBM).
Nivolumab; Ipilimumab; Bevacizumab

Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Clinical Trial using DEC-205-NY-ESO-1 fusion protein vaccine; sirolimus; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Phase I Clinical Trial of mTOR Inhibition With Rapamycin for Enhancing Intranodal Dendritic Cell Vaccine Induced Anti-tumor Immunity in Patients With NY-ESO-1 Expressing Solid Tumors.
DEC-205-NY-ESO-1 fusion protein vaccine; sirolimus; laboratory biomarker analysis

Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Clinical Trial using Montanide ISA-51/survivin peptide vaccine; sargramostim; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Phase I Study of Safety, Tolerability and Immunological Effects of SVN53-67/M57-KLH in Patients With Survivin-Positive Malignant Gliomas.
Montanide ISA-51/survivin peptide vaccine; sargramostim; laboratory biomarker analysis

Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma, Adult Clinical Trial using 3-Tesla magnetic resonance imaging; CEST-MRI; DW-MRI; DCE-MRI; DSC-MRI; IV administration of gadolinium-containing contrast agent

Vanderbilt-Ingram Cancer Center - Recruiting 18 years or older.
- Early Detection of Glioma Treatment Response Using MRI-Based Biomarkers.
3-Tesla magnetic resonance imaging; CEST-MRI; DW-MRI; DCE-MRI; DSC-MRI; IV administration of gadolinium-containing contrast agent

Adult Anaplastic Oligodendroglioma, Adult Giant Cell Glioblastoma Clinical Trial using trebananib; placebo; bevacizumab; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Double-Blinded Placebo-Controlled Study of Bevacizumab With or Without AMG 386 in Patients With Recurrent Glioblastoma or Gliosarcoma.
trebananib; placebo; bevacizumab; pharmacological study; laboratory biomarker analysis

Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Clinical Trial using anti-endoglin monoclonal antibody TRC105; bevacizumab; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase I/Comparative Randomized Phase II Trial of TRC105 Plus Bevacizumab Versus Bevacizumab in Bevacizumab-Na‹ve Patients With Recurrent Glioblastoma Multiforme.
anti-endoglin monoclonal antibody TRC105; bevacizumab; laboratory biomarker analysis; pharmacological study

Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma, Adult Clinical Trial using Temozolomide; hypofractionated radiation therapy; bevacizumab; questionnaire administration

Northwestern University - Recruiting 18 years or older.
- A Phase II Study of the Efficacy of Hypofractionated Radiation Therapy With Bevacizumab and Temozolomide Followed by Maintenance Temozolomide and Bevacizumab for Recurrent High-Grade Gliomas.
Temozolomide; hypofractionated radiation therapy; bevacizumab; questionnaire administration

Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Clinical Trial using vorinostat; stereotactic body radiation therapy; laboratory biomarker analysis; pharmacological study; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- High-Dose Vorinostat With Radiation Therapy in the Treatment of Recurrent Glioma.
vorinostat; stereotactic body radiation therapy; laboratory biomarker analysis; pharmacological study; therapeutic conventional surgery

Malignant Glioma, Glioblastoma Multiforme, Anaplastic Astrocytoma Clinical Trial using Dendritic Cell Vaccine; Tumor Lysate; Imiquimod; Leukapheresis

University of Miami Sylvester Comprehensive Cancer Center - Recruiting 13 years or older.
- Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects.
Dendritic Cell Vaccine; Tumor Lysate; Imiquimod; Leukapheresis