68 results found.

Healthy Volunteers Clinical Trial using Pomegranate Juice; Placebo

University of California, Los Angeles - Recruiting 50 years to 75 years.
- Twelve-Month, Double-blind, Placebo-Controlled Study of Pomegranate Juice in Normal Aging.
Pomegranate Juice; Placebo

HIV-1 Infection Clinical Trial using Raltegravir

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- A Non-interventional Cohort Study for the Assessment of the Efficacy of RALTEGRAVIR 400 mg Administered Twice Daily in Combination With Other Antiretroviral Drugs to Treat Infection With the Human Immunodeficiency Virus 1 (HIV-1) in Adults and Aging Patients (ò 50 Years) Under Conditions That Are Representative of the Nationwide Treatment of HIV-positive Patients in Germany.
Raltegravir

Heart Disease, Physical Frailty, or Exaggerated Personality Trait Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 14 years or older.
- Genetics and Epidemiology of Aging Associated Conditions in the Sardinian Population (SARDINIA).

Normal Aging, or Anemia Clinical Trial using Biotin RBC survival

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Assessing Mechanisms Accounting for Unexplained Anemia in the Elderly.
Biotin RBC survival

Alzheimer's Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 60 years or older.
- Early Markers of Cognitive Change and Alzheimer's Disease: A Propsective Study of the Effects of Aging on Cognition and Brain Pathology.

Alzheimer's Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 20 years or older.
- Early Markers of Alzheimer's Disease in BLSA Participants: Structural and Functional Brain Changes.

Alzheimer's Disease Clinical Trial using BNC

National Institutes of Health Clinical Center (CC) - Recruiting 55 years or older.
- Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult Volunteers.
BNC

Tissue Procurement Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Tissue Procurement for Biomedical Research.

Ataxia, or Dystonia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Genetic Characterization of Movement Disorders.

Glucose Metabolism, or Insulin Resistance Clinical Trial using CP-945,598; Hypoglycemic Clamp; Euglycemic-Hyperinsulinemic Clamp

National Institutes of Health Clinical Center (CC) - Recruiting 21 years to 55 years.
- The Roles of Endocannabinoids in Insulin Secretion and Action.
CP-945,598; Hypoglycemic Clamp; Euglycemic-Hyperinsulinemic Clamp

Dementia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- The Genetic Characterization of Dementia.

Congestive Heart Failure Clinical Trial using Oral R,R'-Fenoterol; Oral Racemic Fenoterol

National Institutes of Health Clinical Center (CC) - Recruiting 21 years to 60 years.
- A Study of (R, R') and (S,S': R,R')- Fenoterol: Initial Clinical Evaluation for Pharmacokinetics, Pharmacodynamics, and Safety.
Oral R,R'-Fenoterol; Oral Racemic Fenoterol

Alzheimer's Disease Clinical Trial using AC-1204; Placebo

Accera, Inc. - Recruiting 66 years to 90 years.
- A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension.
AC-1204; Placebo

Healthy Elderly Clinical Trial using Polyphenol-rich extract; Placebo

Laval University - Recruiting 60 years to 70 years.
- Effect of a Polyphenol-rich Food Supplement on Cognitive Function in Healthy Aging Adults: Randomized, Placebo-controlled, Double-blind Clinical Trial.
Polyphenol-rich extract; Placebo

Age-Associated Decline, or Aging Immune System Clinical Trial using human recombinant growth hormone (Growth Hormone)

National Institutes of Health Clinical Center (CC) - Recruiting 25 years to 50 years.
- Growth Hormone Administration and the Human Immune System.
human recombinant growth hormone (Growth Hormone)

Aging Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Development of 3T Magnetic Resonance Research Methods for NIA Studies.

Hypertension, or Aging Clinical Trial using Exercise; ACE inhibitor + exercise; Thiazide diuretic + exercise; Angiotensin receptor blocker + exercise

University of Florida - Recruiting 65 years or older.
- Multimodal Intervention to Reduce Cardiovascular Risk Among Hypertensive Older Adults.
Exercise; ACE inhibitor + exercise; Thiazide diuretic + exercise; Angiotensin receptor blocker + exercise

Presbycusis, Aging, or Hearing Loss Clinical Trial using hearing aid

Indiana University - Recruiting 55 years to 79 years.
- Evaluating Hearing Aid Service Delivery Models.
hearing aid

Presbycusis, Aging, or Hearing Loss Clinical Trial using Auditory training program; Sham Comparator: Active Control

Indiana University - Recruiting 55 years to 79 years.
- At-home Auditory Training Clinical Trial.
Auditory training program; Sham Comparator: Active Control

Aging Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 20 years or older.
- Longitudinal Studies of Human Physiology, Biochemistry, and Psychology (The Baltimore Longitudinal Syudy of Aging - BLSA).

Non-cancer Affected Volunteers Clinical Trial using Saliva or Blood samples

Memorial Sloan-Kettering Cancer Center - Recruiting 60 years or older.
- Ascertainment of Saliva or Blood Samples For Genetic Epidemiology Studies of Cancer and Aging.
Saliva or Blood samples

Alzheimer's Disease Clinical Trial using Exendin-4 (Exenatide)

National Institutes of Health Clinical Center (CC) - Recruiting 60 years or older.
- A Clinical Trial of Exendin-4 for the Treatment of Alzheimer's Disease.
Exendin-4 (Exenatide)

Hypertension, or Atherosclerosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 50 years to 90 years.
- Age-Associated Changes in Regional Adiposity and Novel Cardiovascular Risk Factors.

HIV, COPD, Chronic Obstructive Pulmonary Disease, or Smoking Clinical Trial using Examination of the interaction of HIV directly on the small airway epithelium

Weill Medical College of Cornell University - Recruiting 18 years or older.
- HIV-related Accelerated Aging of the Airway Epithelium.
Examination of the interaction of HIV directly on the small airway epithelium

Aging Clinical Trial using Home-based, DVD-delivered physical activity; Usual care/Wait list

University of Illinois at Urbana-Champaign - Recruiting 65 years to 85 years.
- Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life.
Home-based, DVD-delivered physical activity; Usual care/Wait list

Alzheimer's Disease Clinical Trial using TPI-287 2 mg/m2; TPI-287 6.3 mg/m2; TPI-287 20 mg/m2; Placebo

University of California, San Francisco - Recruiting 50 years to 82 years.
- A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of TPI-287 in Patients With Mild to Moderate Alzheimer's Disease.
TPI-287 2 mg/m2; TPI-287 6.3 mg/m2; TPI-287 20 mg/m2; Placebo

Ageing Clinical Trial using high intensity interval training; moderate intensity training

Norwegian University of Science and Technology - Recruiting 70 years to 75 years.
- Generation 100: How Exercise Affects Mortality and Morbidity in the Elderly: A Randomized Control Study.
high intensity interval training; moderate intensity training

Dementia Clinical Trial using High intensity aerobic training; Sedentary Control

Mayo Clinic - Recruiting 18 years to 80 years.
- Effect of Aging and Aerobic Exercise Training on Brain Glucose Metabolism.
High intensity aerobic training; Sedentary Control

Menopause, Aging, or Vascular Health Clinical Trial using KUVAN; Placebo; Cetrotide; Climara; Placebo transdermal patch

University of Colorado, Denver - Recruiting 18 years to 70 years.
- Biological Mechanisms of Vascular Dysfunction With Age and Estrogen Deficiency.
KUVAN; Placebo; Cetrotide; Climara; Placebo transdermal patch

Urinary Incontinence, or Urinary Stress Incontinence Clinical Trial using Group physiotherapy; Individual one-on-one physiotherapy

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal - Recruiting 60 years or older.
- Group Physiotherapy Compared to Individual Physiotherapy to Treat Urinary Incontinence in Aging Women: A Randomized Control Trial.
Group physiotherapy; Individual one-on-one physiotherapy

Well Being Clinical Trial using Choir program

University of California, San Francisco - Recruiting 60 years or older.
- Community Choirs To Promote Healthy Aging And Independence Of Older Adults.
Choir program

Dyslipidemia Clinical Trial using Diet

Tufts University - Recruiting 50 years or older.
- Dietary Carbohydrate Type and CVD Risk Indicators.
Diet

HIV Infection, Cardiovascular Disease, or Inflammation Clinical Trial

University of California, San Francisco - Recruiting 40 years to 80 years.
- The Role of Inflammation and Aging in HIV-Associated Cardiovascular Risk.

Aging Clinical Trial using Aerobic and strength training group; Balance and flexibility group

University of Texas Southwestern Medical Center - Recruiting 45 years to 64 years.
- The Effect of Long Duration Exercise on the Diastolic Function of the Heart.
Aerobic and strength training group; Balance and flexibility group

Aging, Stress, or Disease Risk Clinical Trial using Aerobic Training Intervention

University of California, San Francisco - Recruiting 50 years to 75 years.
- The Effects of Exercise and Life Stress on Telomere Maintenance and Cardiovascular Disease Risk.
Aerobic Training Intervention

Sarcopenia, Frailty, or Aging Clinical Trial using Muscle Biopsy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Muscle Biopsies in Healthy Volunteers: a Pilot Study.
Muscle Biopsy

Cytapheresis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Cytapheresis of Volunteer Donors.

Age Related Cognitive Decline, or Age Related Macular Degeneratio Clinical Trial using Walnuts; habitual diet

Loma Linda University - Recruiting 65 years to 75 years.
- Effect of Daily Ingestion of Walnuts for 2 Years on Age-related Cognitive Decline and Macular Degeneration in Healthy Elderly Subjects: A Randomized, Single Blind, Dual Center, Controlled Trial.
Walnuts; habitual diet

Aging Clinical Trial using High intensity aerobic interval training; Continuous moderate intensity exercise

University of Florida - Recruiting 18 years to 79 years.
- Effect of Aerobic Interval vs. Continuous Exercise Training on Cardiovascular Function in Aging.
High intensity aerobic interval training; Continuous moderate intensity exercise

Healthy People Programs Clinical Trial using Memory and Aging Course

Department of Veterans Affairs - Recruiting 65 years or older.
- Maintaining Cognitive Health in Aging Veterans.
Memory and Aging Course

Mild Cognitive Impairment Clinical Trial using Atkins low carbohydrate diet; Healthy high carbohydrate diet

University of Cincinnati - Recruiting 60 years or older.
- Energy Metabolism and Cognitive Aging.
Atkins low carbohydrate diet; Healthy high carbohydrate diet

Vascular Aging Clinical Trial using Placebo; Sodium Nitrite

University of Colorado, Boulder - Recruiting 50 years to 79 years.
- Clinical Translation of Nitrite Therapy to Treat Arterial Aging in Humans.
Placebo; Sodium Nitrite

Aging Clinical Trial using PREPARE website; Advance directive

Department of Veterans Affairs - Recruiting 60 years or older.
- Preparing Older Veterans With Serious and Chronic Illness for Decision Making.
PREPARE website; Advance directive

Metabolic Syndrome, Diabetes, or Aging Clinical Trial using US; IW; CW

University of Colorado, Denver - Recruiting 60 years to 85 years.
- Effects of Interrupting Sedentary Time on Glycemic Control in Older Overweight and Obese Adults.
US; IW; CW

Sarcopenia Clinical Trial using ARFI

University Hospital, Bordeaux - Recruiting 18 years or older.
- .
ARFI

Mild Cognitive Impairment (MCI), or Alzheimer's Disease Clinical Trial

Alzheimer's Disease Cooperative Study (ADCS) - Recruiting 55 years to 90 years.
- Alzheimer's Disease Neuroimaging Initiative 2.

Aging Clinical Trial using L[ring-13C6]phenylalanine

Mayo Clinic - Recruiting 18 years or older.
- Novel Methodology to Measure Protein Accumulation.
L[ring-13C6]phenylalanine

Aging, Exercise, or Cardiovascular Disease Clinical Trial using Exercise Training; Exercise Cessation

Baltimore VA Medical Center - Recruiting 50 years to 80 years.
- Regulation of Endothelial Progenitor Cells by Short-Term Exercise.
Exercise Training; Exercise Cessation

Cognitive Impairment Clinical Trial using Dual task gait training; Aerobic exercise class

Parkwood Hospital, London, Ontario - Recruiting 60 years to 85 years.
- Study of Community Based and Institutional Dual Task and Aerobic Exercise Intervention on Cognition and Mobility in Older Adults With Cognitive Impairment-no Dementia.
Dual task gait training; Aerobic exercise class

Healthy Clinical Trial

University of Utah - Recruiting 18 years to 75 years.
- .

Aging Clinical Trial using Cognitive Training; Strength Training; FortiFit

University of Vienna - Recruiting 65 years or older.
- Influence of Strength Training and Nutritional Supplementation on Physical Performance and Well-being of Older People in Pensioner Homes.
Cognitive Training; Strength Training; FortiFit

Obesity Clinical Trial using GnRH agonist; Supervised cardiovascular exercise

University of Colorado, Denver - Recruiting 42 years to 52 years.
- Bioenergetic and Metabolic Consequences of the Loss of Ovarian Function in Women.
GnRH agonist; Supervised cardiovascular exercise

Obesity Clinical Trial using energy restricted mediterranean-type diet; 25 % calorie restriction

University of Chile - Recruiting 25 years to 40 years.
- Calorie Restriction Retards the Aging Process by Inducing Sirtuins and Uncoupling Protein 3, Thereby Reducing the Production of Reactive Oxygen Species..
energy restricted mediterranean-type diet; 25 % calorie restriction

Sarcopenia Clinical Trial using Amino acid supplement; Exercise

The University of Texas, Galveston - Recruiting 65 years to 85 years.
- Nutrition and Exercise to Improve Protein Metabolism and Prevent Sarcopenia in Aging.
Amino acid supplement; Exercise

Knee Osteoarthritis Clinical Trial using preoperative neuromuscular training; knee OA School

University of Zurich - Recruiting 60 years to 85 years.
- Effect of Pre-surgery Neuromuscular Physiotherapy (PT) on Functional Outcome After Total Knee Replacement (TKR): A Single-blinded Randomized Controlled Trial..
preoperative neuromuscular training; knee OA School

Alzheimer's Disease Clinical Trial

National Institute on Aging (NIA) - Recruiting 60 years to 90 years.
- Implications of Amyloid Deposition in Clinically Normal Older Individuals.

Down Syndrome, or Alzheimer's Disease Clinical Trial

National Institute on Aging (NIA) - Recruiting 21 years or older.
- Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome.

Intermittent Claudication Clinical Trial using Walking Exercise; Control--Resistance Training

National Institute on Aging (NIA) - Recruiting 35 years or older.
- Home-based vs. Supervised Exercise for Claudicants.
Walking Exercise; Control--Resistance Training

Osteoporosis Clinical Trial

Odense University Hospital - Recruiting 60 years to 70 years.
- Study on Male Osteoporosis and Aging.