125 results found.

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 18 years or older.
- A Post-Marketing Observational Study (PMOS) to Determine the Effectiveness and Patient Satisfaction With Adalimumab Treatment in Patients With Rheumatoid Arthritis (OPERA Study).

Rheumatoid Arthritis Clinical Trial using apremilast; Placebo

Baylor Research Institute - Recruiting 18 years or older.
- The Controlled Trial of Apremilast for Rheumatoid Arthritis Treatment.
apremilast; Placebo

Arthritis, Rheumatoid, or Healthy Clinical Trial using BI 655064 medium dose; BI 655064 high dose; Placebo; BI 655064 low dose

Boehringer Ingelheim - Recruiting 18 years to 70 years.
- A Randomised, Double-blind, Placebo-controlled Trial for Establishing Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Efficacy of Multiple Subcutaneous Doses of BI 655064 in Healthy Volunteers and in Rheumatoid Arthritis Patients With Prior Inadequate Response to Methotrexate Therapy.
BI 655064 medium dose; BI 655064 high dose; Placebo; BI 655064 low dose

Arthritis, Rheumatoid Clinical Trial using BI 695500; rituximab

Boehringer Ingelheim - Recruiting 18 years to 80 years.
- Efficacy, Pharmacokinetics, and Safety of BI 695500 Versus Rituximab in Patients With Moderately to Severely Active Rheumatoid Arthritis: a Randomized, Double-blind, Parallel Arm, Multiple Dose, Active Comparator Trial..
BI 695500; rituximab

Arthritis, Rheumatoid Clinical Trial using BI 695500

Boehringer Ingelheim - Recruiting 18 years to 82 years.
- Safety and Efficacy of BI 695500 in Patients With Moderately to Severely Active Rheumatoid Arthritis: an Open-label Extension Trial.
BI 695500

Rheumatoid Arthritis Clinical Trial using Etanercept; Abatacept; Rituximab; Adalimumab; Certolizumab Pegol; Infliximab; Golimumab

University of Leeds - Recruiting 18 years or older.
- Randomised-controlled Trial of Switching to Alternative Tumour-necrosis Factor (TNF)-Blocking Drugs or Abatacept or Rituximab in Patients With Rheumatoid Arthritis Who Have Failed an Initial TNF-blocking Drug.
Etanercept; Abatacept; Rituximab; Adalimumab; Certolizumab Pegol; Infliximab; Golimumab

Rheumatoid Arthritis Clinical Trial using Protein; Carbohydrate (Placebo); Resistance Exercise Program

Johns Hopkins University - Recruiting 60 years to 95 years.
- The PRESS RA Study: Protein and Resistance Exercise Supplementation Study for Rheumatoid Arthritis.
Protein; Carbohydrate (Placebo); Resistance Exercise Program

Rheumatoid Arthritis Clinical Trial using Etanercept; Etnaercept; Placebo

Pfizer - Recruiting 18 years to 79 years.
- A Randomized, Double-blind, Placebo-controlled Study of the Safety and Efficacy of Etanercept in Subjects With Rheumatoid Arthritis Who Have Had an Inadequate Response to Adalimumab or Infliximab Plus Methotrexate.
Etanercept; Etnaercept; Placebo

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 18 years or older.
- A Prospective, Multi-center, Post-marketing Observational Study on Rheumatoid Arthritis Patients on Adalimumab to Evaluate Its Effect on Synovitis Using Ultrasonography on Egyptian Population.

Rheumatoid Arthritis Clinical Trial using vascular occlusion with exercise trainig; high intensity resistance training

University of Sao Paulo - Recruiting 30 years to 70 years.
- Effects of Strength Training With Vascular Occlusion in Patients With Rheumatoid Arthritis: A Randomized Clinical Trial.
vascular occlusion with exercise trainig; high intensity resistance training

Rheumatoid Arthritis Clinical Trial using GLPG0634; Placebo

Galapagos NV - Recruiting 18 years or older.
- Randomized, Double-blind, Placebo-controlled, Multicenter, Phase IIb Dose Finding Study of GLPG0634 Administered for 24 Weeks in Combination With Methotrexate to Subjects With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Alone.
GLPG0634; Placebo

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 18 years or older.
- Long Term Documentation of the Safety and Efficacy as Well as the Effects on Quality of Life and Work Productivity in Patients With Rheumatoid Arthritis Under HUMIRAr (Adalimumab) in Routine Clinical Practice (AGIL).

Rheumatoid Arthritis Clinical Trial using Repository corticotropin injection

Arthritis Treatment Center, Maryland - Recruiting 18 years to 80 years.
- Repository Corticotropin Injection As Adjunctive Therapy In Patients With Rheumatoid Arthritis Who Have Failed At Least Three Biologic Therapies With Different Modes Of Action.
Repository corticotropin injection

Inflammation, or Rheumatoid Arthritis Clinical Trial using NNC0215-0384; placebo

Novo Nordisk - Recruiting 18 years to 75 years.
- A Randomised, Placebo-controlled, Double-blind Within Cohort, Dose Escalation, Multiple-dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0215-0384 Administered Subcutaneously to Subjects With Moderate to Severe Rheumatoid Arthritis.
NNC0215-0384; placebo

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- An Observational Study on the Efficacy and Safety of MabThera (Rituximab) in seroPOSITIVE TNF IR Patients With Severe Active Rheumatoid Arthritis in Routine Clinical Practice (POSITIVE TRIAL).

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Mon-ACT: A Multi-center, Non-interventional Study in Rheumatoid Arthritis (RA) Patients Treated With Tocilizumab in Monotherapy.

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; DMARDs

Hoffmann-La Roche - Recruiting 18 years or older.
- A NATIONAL, OPEN-LABEL, SINGLE-ARM, PHASE IIIB STUDY TO EVALUATE THE EFFICACY OF WEEKLY TOCILIZUMAB SUBCUTANEOUS, ADMINISTERED AS MONOTHERAPY OR IN COMBINATION WITH METHOTREXATE AND/OR OTHER DMARDS IN RHEUMATOID ARTHRITIS (RA) PATIENTS..
tocilizumab [RoActemra/Actemra]; DMARDs

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- HAQIMONO a Non-interventional National Multicenter Study, Observing RA Patients Treated With Tocilizumab in Mono-therapy, i.e. Without Combination With DMARD.

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Global Comparative Observational Study In Rheumatoid Arthritis (RA) Patients Who Are Treated With A TNF Inhibitor Or Tocilizumab As The First Biologic Therapy.

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; DMARDs; corticosteroids

Hoffmann-La Roche - Recruiting 18 years or older.
- Open-label, Phase IIIb Study to Evaluate the Efficacy and Safety of Subcutaneous (SC) Tocilizumab Monotherapy or Combination Therapy With Methotrexate (MTX) or Other Non-biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) in Patients With Severe Rheumatoid Arthritis (RA) Who Are Being Treated With an Anti-tumour Necrosis Factor (Anti-TNF) Agent and That Have Not Achieved an Adequate Response to Treatment.
tocilizumab [RoActemra/Actemra]; DMARDs; corticosteroids

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multicenter, Open-Label, Single-Arm Extension Study To Describe The Safety Of Tocilizumab Treatment In Brazilian Patients With DMARDs Refractory Rheumatoid Arthritis Which Completed Studies ML21530 And MA21488 And Presenting An Indication Of Maintaining The Tocilizumab Treatment.
tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting 18 years or older.
- An Open-label, Single Arm Study to Evaluate the Efficacy and Safety and Tolerability of Tocilizumab (TCZ) Subcutaneous in TCZ-na‹ve Patients With Active Rheumatoid Arthritis.
tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; methotrexate; placebo

Hoffmann-La Roche - Recruiting 18 years or older.
- A RANDOMIZED, DOUBLE-BLIND TRIAL ASSESSING THE IMPACT OF METHOTREXATE DISCONTINUATION ON THE EFFICACY OF SUBCUTANEOUS TOCILIZUMAB WITH METHOTREXATE THERAPY.
tocilizumab [RoActemra/Actemra]; methotrexate; placebo

Rheumatoid Arthritis Clinical Trial using Venous blood sample

Assistance Publique Hopitaux De Marseille - Recruiting 18 years or older.
- Monitoring EBV Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs ; Orencia* (Abatacept) and RoActemra* (Tocilizumab)..
Venous blood sample

Rheumatoid Arthritis Clinical Trial using Lodotrar

Mundipharma Korea Ltd - Recruiting 20 years to 80 years.
- A New Modified-Release Tablet Formulation of Prednisone in Patients With Rheumatoid Arthritis- Multicenter, Phase IV, Interventional Study to Assess Reduction of Morning Stiffness.
Lodotrar

Rheumatoid Arthritis Clinical Trial using TNF inhibitors; Synthetic DMARD(s); Co-medication: Synthetic DMARDs

Diakonhjemmet Hospital - Recruiting 18 years to 80 years.
- REmission in Rheumatoid Arthritis - Assessing WIthrawal of Disease-modifying Antirheumatic Drugs in a Non-inferiority Design.
TNF inhibitors; Synthetic DMARD(s); Co-medication: Synthetic DMARDs

Arthritis, Rheumatoid Clinical Trial using ABP 501; Adalimumab (Humirar)

Amgen - Recruiting 18 years to 80 years.
- A Randomized, Double-blind, Phase 3 Study of ABP 501 Efficacy and Safety Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis.
ABP 501; Adalimumab (Humirar)

Arthritis, Rheumatoid Clinical Trial using Placebo; Sirukumab

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis Despite DMARD Therapy.
Placebo; Sirukumab

Rheumatoid Arthritis, Lupus Erythematosus, Systemic, or Sjogren's Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 24 years or older.
- Agricultural Health Study: Health Follow-up.

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; methotrexate; DMARD

Hoffmann-La Roche - Recruiting 18 years or older.
- A PHASE IIIb STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF SUBCUTANEOUS (SC) TOCILIZUMAB (TCZ) GIVEN AS MONOTHERAPY OR IN COMBINATION WITH METHOTREXATE (MTX) OR OTHER NON BIOLOGICS DMARDs IN SUBJECTS WITH RHEUMATOID ARTHRITIS.
tocilizumab [RoActemra/Actemra]; methotrexate; DMARD

Rheumatoid Arthritis Clinical Trial using Sarilumab SAR153191 (REGN88); Etanercept; Adalimumab

Sanofi - Recruiting 18 years or older.
- A Randomized, Controlled Study of Sarilumab and Methotrexate (MTX) Versus Etanercept and MTX in Patients With Rheumatoid Arthritis (RA) and an Inadequate Response to 4 Months of Treatment With Adalimumab and MTX.
Sarilumab SAR153191 (REGN88); Etanercept; Adalimumab

Rheumatoid Arthritis Clinical Trial using sarilumab SAR153191 (REGN88); placebo

Sanofi - Recruiting 18 years or older.
- A Randomized, Double-blind, Parallel, Placebo-controlled Study Assessing the Efficacy and Safety of Sarilumab Added to Non-biologic DMARD Therapy in Patients With Rheumatoid Arthritis Who Are Inadequate Responders to or Intolerant of TNF-à Antagonists.
sarilumab SAR153191 (REGN88); placebo

Rheumatoid Arthritis Clinical Trial using sarilumab SAR153191 (REGN88); tocilizumab

Sanofi - Recruiting 18 years or older.
- A Randomized, Double-Blind, Double-Dummy Study Assessing The Safety and Tolerability of Sarilumab and Tocilizumab In Patients With Rheumatoid Arthritis Who Are Inadequate Responders to or Intolerant of TNF Antagonists.
sarilumab SAR153191 (REGN88); tocilizumab

Arthritis, Rheumatoid Clinical Trial using Golimumab 2 mg/kg IV

Janssen Biotech, Inc. - Recruiting 18 years to 76 years.
- A Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADEr).
Golimumab 2 mg/kg IV

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multicenter, Open-Label, Single Arm, Long Term Extension Study of WA 19926 to Describe Safety During Treatment With Tocilizumab in Patients With Early, Moderate to Severe Rheumatoid Arthritis.
tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; methotrexate

Hoffmann-La Roche - Recruiting 18 years or older.
- Randomised, Phase IV, Placebo-controlled, Comparative Study to Evaluate the Efficacy and Safety of Tapering Methotrexate (MTX) Dosage Versus Maintaining the Dosage in Patients With Severe Active Rheumatoid Arthritis (RA) Who Have Demonstrated an Inadequate Response to Prior Conventional Disease-modifying Anti-rheumatic Drugs (DMARDs) Treatment and Have Initiated RoActemrar (Tocilizumab, TCZ) in Combination With MTX.
tocilizumab [RoActemra/Actemra]; methotrexate

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Tocilizumab (RoActemra) poST Marketing Observational Study in DMARD-IR Patients to Assess Efficacy and Safety in routiNE Clinical Practice - STONE.

Rheumatoid Arthritis Clinical Trial using Musculoskeletal Ultrasound; Semi-structured patient interview

Newcastle-upon-Tyne Hospitals NHS Trust - Recruiting 18 years or older.
- A Pilot Study of Musculoskeletal Ultrasound Assessment in Patients With Rheumatoid Arthritis.
Musculoskeletal Ultrasound; Semi-structured patient interview

Progression of Rheumatoid Arthritis Clinical Trial using Prednisolone; Placebo

Ruhr University of Bochum - Recruiting 18 years or older.
- Comparison of the Efficacy and Safety of Two Different Starting Dosages of Prednisolone in Early Active Rheumatoid Arthritis: a Randomized, Placebo Controlled Trial.
Prednisolone; Placebo

Arthritis, Rheumatoid Clinical Trial using Placebo; Sirukumab

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy.
Placebo; Sirukumab

Arthritis, Juvenile Rheumatoid Clinical Trial using Sulfasalazine

Pfizer - Recruiting 6 years to 17 years.
- An Open Label Non-Randomized Study To Characterize The Steady State Pharmacokinetics Of Sulfasalazine Delayed Release Tablets In Children With Juvenile Idiopathic Arthritis.
Sulfasalazine

Rheumatoid Arthritis Clinical Trial using Baricitinib; Methotrexate; Placebo; Folic Acid

Eli Lilly and Company - Recruiting 18 years or older.
- A Randomized, Double-Blind, Active-Controlled,Phase 3 Study to Evaluate the Efficacy and Safety of Baricitinib (LY3009104) in Patients With Moderately to Severely Active Rheumatoid Arthritis Who Have Had Limited or No Treatment With Disease-Modifying Antirheumatic Drugs.
Baricitinib; Methotrexate; Placebo; Folic Acid

Crohn's Disease, or Rheumatoid Arthritis Clinical Trial

University of California, San Diego - Recruiting N/A or older.
- Cimzia (Certolizumab Pegol) Pregnancy Exposure Registry: OTIS Autoimmune Diseases in Pregnancy Project.

Rheumatoid Arthritis Clinical Trial

UCB, Inc. - Recruiting 18 years or older.
- A Multi-center, Noninterventional Study With Certolizumab Pegol in Comparison With Any Other Subcutaneous TNF Inhibitor in Two Parallel Groups in Biologic Naive Patients With Rheumatoid Arthritis.

Rheumatoid Arthritis Clinical Trial using Allogeneic Mesenchymal Precursor Cells; Normal Saline

Mesoblast, Ltd. - Recruiting 18 years to 80 years.
- A Double-blind, Randomized, Placebo-controlled, Dose-escalation, Multi-center Study a Single Intravenous Infusion of Allogeneic Mesenchymal Precursor Cells (MPCs) in Patients With Rheumatoid Arthritis and Incomplete Response to at Least One TNF Alpha Inhibitor..
Allogeneic Mesenchymal Precursor Cells; Normal Saline

Rheumatoid Arthritis Clinical Trial using Secukinumab (AIN457)

Novartis - Recruiting 18 years or older.
- A Four Year Extension Study to Evaluate the Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Rheumatoid Arthritis.
Secukinumab (AIN457)

Moderate to Severe Rheumatoid Arthritis Clinical Trial using etanercept

Amgen - Recruiting 18 years or older.
- A Single Arm Trial to Evaluate the Efficacy of Etanercept in Moderate to Severe Rheumatoid Arthritis Patients Who Failed to Respond or Lost a Satisfactory Response to Treatment With Adalimumab When Used as Their First Biologic Agent.
etanercept

Arthritis, Rheumatoid, Spondylarthritis, or Vasculitis Clinical Trial using Hepatitis A vaccine and tetanus vaccine

University of Zurich - Recruiting 18 years or older.
- A Prospective Cohort Study in 6 Swiss Rheumatology Centres and 4 Travel Clinics on the Immunogenicity and Safety of Tetanus and Hepatitis A Vaccine in Patients With Rheumatoid Arthritis, Axial Spondyloarthritis and Vasculitis and Healthy Controls.
Hepatitis A vaccine and tetanus vaccine

Cardiovascular Disease, Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]; etanercept

Hoffmann-La Roche - Recruiting 50 years or older.
- A Clinical Outcomes Study to Evaluate the Effects of IL-6 Receptor Blockade With Tocilizumab (TCZ) in Comparison With Etanercept (ETA) on the Rate of Ischemic Cardiovascular Events in Patients With Moderate to Severe Rheumatoid Arthritis (RA).
tocilizumab [RoActemra/Actemra]; etanercept

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Multicenter, Post-marketing, Non-interventional, Observational Study in RA Patients Treated With Tocilizumab..

Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Eryt Clinical Trial using Interleukin 2

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Induction of Regulatory t Cells by Low Dose IL2 in Autoimmune and Inflammatory Diseases: a Transnosographic Approach.
Interleukin 2

Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Ne Clinical Trial using Shoulder Arthroplasty

Zimmer, Inc. - Recruiting 18 years to 80 years.
- Sidus(TM) Stem-Free Shoulder - A Multi-center, Prospective, Non-controlled Post Market Clinical Follow-up Study..
Shoulder Arthroplasty

Rheumatoid Arthritis, or Targeted Ultrasound Clinical Trial using Adalimumab

University of Leeds - Recruiting 18 years or older.
- Targeted Ultrasound in Rheumatoid Arthritis.
Adalimumab

Rheumatoid Arthritis Clinical Trial using Hematopoietic Stem Cell Transplantation

Northwestern University - Recruiting 18 years to 60 years.
- Rheumatoid Arthritis: Tolerance Induction by Mixed Chimerism.
Hematopoietic Stem Cell Transplantation

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Non-interventional Local Study to Describe the Safety, Tolerability and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-biologic DMARD.

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multi-national, Multi-center Non-interventional Study in Rheumatoid Arthritis (RA) Patients Treated With Tocilizumab.

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 20 years or older.
- .

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 20 years or older.
- A Non-interventional Study for Relative Efficacy Outcome of Rituximab Treatment in RA Patients Who Have Inadequate Response or Have Been Intolerant to a First Anti-TNF Agent.

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Non-interventional, Prospective, Multicenter Study to Assess Efficacy and Safety of MabtheRA (Rituximab) in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response or Intolerance to One Anti-TNF Agent - FAST 2 SWITCH Program.

Rheumatoid Arthritis Clinical Trial using GLPG0634; Placebo

Galapagos NV - Recruiting 18 years or older.
- Randomized, Double-blind, Placebo-controlled, Multicenter, Phase IIb Dose Finding Study of GLPG0634 Administered for 24 Weeks as Monotherapy to Subjects With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate (MTX) Alone.
GLPG0634; Placebo

Rheumatoid Arthritis Clinical Trial using SAN-300; Placebo

Santarus - Recruiting 18 years to 75 years.
- A Randomized, Double-blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Escalating Doses of SAN-300 in Patients With Active Rheumatoid Arthritis With Inadequate Response to Disease-Modifying Anti-rheumatic Drug(s)..
SAN-300; Placebo

First Degree Relatives of Rheumatoid Arthritis Patients Clinical Trial using PRE-RA; PRE-RA Plus; General Rheumatoid Arthritis Education

Brigham and Women's Hospital - Recruiting 18 years to 70 years.
- Communication of Biomarker, Genetic, and Lifestyle Risk Factor Profiles for Rheumatoid Arthritis to First Degree Relatives.
PRE-RA; PRE-RA Plus; General Rheumatoid Arthritis Education

Arthritis, Rheumatoid Clinical Trial using Etoricoxib 60 mg; Etoricoxib 90 mg; Placebo to Etoricoxib 60 mg; Placebo to Etoricoxib 90 mg

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- A Phase III, Two-Part, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Clinical Trial to Assess the Relative Efficacy and Tolerability of Two Doses of MK-0663/Etoricoxib in Patients With Rheumatoid Arthritis.
Etoricoxib 60 mg; Etoricoxib 90 mg; Placebo to Etoricoxib 60 mg; Placebo to Etoricoxib 90 mg

Rheumatoid Arthritis Clinical Trial using Certolizumab pegol

UCB, Inc. - Recruiting 18 years or older.
- Multicenter, Open Label Study to Evaluate the Predictability of Early Response to Certolizumab Pegol (in Combination With Methotrexate) as Confirmed at Week 52 in Subjects With Moderate-severe Rheumatoid Arthritis (RA).
Certolizumab pegol

Rheumatoid Arthritis, Ankylosing Spondylitis, Lupus Erythematosus Clinical Trial using Employment and Arthritis: Making it Work

University of British Columbia - Recruiting 18 years to 59 years.
- Employment and Arthritis: Making it Work: A Randomized Controlled Trial Evaluating an On-line Program to Help People With Inflammatory Arthritis Remain Employed.
Employment and Arthritis: Making it Work

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multi-Center Observational Study on the Use of Biologic Drugs as Monotherapy or Combination With DMARDs in Patients With Rheumatoid Arthritis in Italian Clinical Practice.

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting 18 years or older.
- Local Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis on Background Non-biologic DMARDs Who Have an Inadequate Response to Current Non-biologic DMARD.
tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multi-Center, Non-inteRventional Study in rheumatOid Arthritis patientS Treated With Tocilizumab in Serbia- ACROSS; (Part of Global Umbrella Project).

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Multinational, Multicenter, Non Interventional Study, in Patients With Rheumatoid Arthritis (RA) Treated With Tocilizumab..

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Prospective, Non-interventional Multi-center Observational Study to Evaluate the Long-term Effectiveness and Safety of Tocilizumab in Patients With Active Rheumatoid Arthritis in Daily Practice.

Juvenile Idiopathic Arthritis, Rheumatoid Arthritis Clinical Trial using Tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting N/A to 24 Months.
- A Phase I Pharmacokinetic and Safety Study of Tocilizumab (TCZ) in Patients Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis (sJIA).
Tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multi-national, Multi-center Non-interventional Study in Rheumatoid Arthritis (RA) Patients Treated With Tocilizumab.

Rheumatoid Arthritis Clinical Trial using tocilizumab [RoActemra/Actemra]

Hoffmann-La Roche - Recruiting 18 years or older.
- Multi-center, Open-label Single Arm Phase IIIb Study on Safety and Efficacy of Subcutaneous (SC) Tocilizumab in Monotherapy or in Combination With Methotrexate (MTX) or Other Non-biologic Disease Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis Patients With an Inadequate Response to Non-biologic DMARDs.
tocilizumab [RoActemra/Actemra]

Rheumatoid Arthritis Clinical Trial using LD-aminopterin; placebo

Syntrix Biosystems, Inc. - Recruiting 18 years or older.
- A Phase 2 Double-Blind, Placebo-Controlled, Randomized Dose Finding Study For The Efficacy And Safety Of Aminopterin In Methotrexate-Naive Rheumatoid Arthritis.
LD-aminopterin; placebo

Rheumatoid Arthritis Clinical Trial using Placebo; Adalimumab; Baricitinib

Eli Lilly and Company - Recruiting 18 years or older.
- A Randomized, Double-Blind, Placebo- and Active-Controlled, Phase 3 Study Evaluating the Efficacy and Safety of Baricitinib in Patients With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate Therapy.
Placebo; Adalimumab; Baricitinib

Rheumatoid Arthritis Clinical Trial using Baricitinib; Placebo

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients With Rheumatoid Arthritis.
Baricitinib; Placebo

Rheumatoid Arthritis Clinical Trial using Sirukumab 100 mg; Sirukumab 50 mg; Placebo

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Multicenter, Parallel-group Study of Long-term Safety and Efficacy of CNTO 136 (Sirukumab) for Rheumatoid Arthritis in Subjects Completing Treatment in Studies CNTO136ARA3002 (SIRROUND-D) and CNTO136ARA3003 (SIRROUND-T).
Sirukumab 100 mg; Sirukumab 50 mg; Placebo

Rheumatoid Arthritis Clinical Trial using adalimumab; Methotrexate

AbbVie - Recruiting 18 years or older.
- Radiographic, Clinical and Patient Outcomes in a Multicenter, Open Label Phase IV Randomized Trial of Earlier Adalimumab Introduction Therapy Versus Later Introduction as Per Standard of Care After Initial Methotrexate Failure in Early Rheumatoid Arthritis Patients.
adalimumab; Methotrexate

Rheumatoid Arthritis Clinical Trial using Placebo; JNJ-38518168 (3 mg); JNJ-38518168 (10 mg); JNJ-38518168 (30 mg)

Janssen Research & Development, LLC - Recruiting 18 years to 80 years.
- A Phase 2b Randomized, Double-blind, Multicenter, Placebo-controlled, Parallel Group, Dose Range Finding Study of JNJ-38518168 in Subjects With Active Rheumatoid Arthritis Despite Concomitant Methotrexate Therapy.
Placebo; JNJ-38518168 (3 mg); JNJ-38518168 (10 mg); JNJ-38518168 (30 mg)

Arthritis, Rheumatoid Clinical Trial using CHR-5154; Placebo

GlaxoSmithKline - Recruiting 18 years to 45 years.
- A Phase 1 Double-blind, Randomised, Placebo-controlled, Dose Escalating Study to Assess the Safety and Tolerability of Single and Multiple Oral Doses of CHR-5154 and the Effect of the Fasted and Fed State on Pharmacokinetics of CHR-5154 and CHR-5426 in Healthy Male Volunteers.
CHR-5154; Placebo

Rheumatoid Arthritis Clinical Trial using PF-04171327; prednisone; placebo

Pfizer - Recruiting 19 years or older.
- A Phase 2, Randomized, Double Blind Assessment Of Efficacy And Safety Of PF-04171327 (1, 5, 10, 15 Mg Dose, Daily) Compared To 5 Mg And 10 Mg Prednisone Daily And Placebo Daily In Subjects With Rheumatoid Arthritis Over An 8 Week Period Followed By A 4 Week Period Of Tapering Of Study Drug.
PF-04171327; prednisone; placebo

Rheumatoid Arthritis Clinical Trial using Etanercept; placebo

Pfizer - Recruiting 18 years to 70 years.
- A Randomized, Double-blind Placebo-controlled Study of the Maintenance of Efficacy of Etanercept Plus Dmard(s) Compared With Dmard(s) Alone in Subjects With Rheumatoid Arthritis After Achieving an Adequate Response With Etanercept Plus Dmard(s).
Etanercept; placebo

Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA, Clinical Trial using Blood draw from mother; Blood draw from infant; Blood draw from umbilical cord; Certolizumab Pegol

UCB, Inc. - Recruiting 18 years or older.
- A Multicenter Postmarketing Study to Evaluate the Placental Transfer of Certolizumab Pegol in Pregnant Women Receiving Treatment With Cimziar (Certolizumab Pegol) Phase 1b (Clinical Pharmacology).
Blood draw from mother; Blood draw from infant; Blood draw from umbilical cord; Certolizumab Pegol

Rheumatoid Arthritis (RA) Clinical Trial using non-interventional study

Pfizer - Recruiting 18 years or older.
- FORMATION OF ANTIBODIES AND SUBSEQUENT PREDICTION OF CLINICAL RESPONSE IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH FOUR TNF BLOCKING AGENTS.
non-interventional study

Arthritis, Rheumatoid Clinical Trial using celecoxib; Ibuprofen; Naproxen

Pfizer - Recruiting 18 years or older.
- A Randomized, Double Blind, Parallel-Group Study Of Cardiovascular Safety In Osteoarthritis Or Rheumatoid Arthritis Patients With Or At High Risk For Cardiovascular Disease Comparing Celecoxib With Naproxen And Ibuprofen.
celecoxib; Ibuprofen; Naproxen

Arthritis, Rheumatoid, or High Dose Clinical Trial using Methotrexate (MTX)

Pfizer - Recruiting 17 years or older.
- Rheumatrex High Dose Special Investigation (Regulatory Post Marketing Commitment Plan).
Methotrexate (MTX)

Rheumatoid Arthritis Clinical Trial using etanercept; methotrexate

Pfizer - Recruiting 18 years or older.
- Ability to Achieve a Good Eular Response in Patients With Moderate-to-severe Active Early Rheumatoid Arthritis Who Satisfy the New ACR/EULAR Classification Criteria Receiving Etanercept + MTX in Real World Clinical Practice in Greece.
etanercept; methotrexate

Rheumatoid Arthritis Clinical Trial using non-intervention

Pfizer - Recruiting 18 years or older.
- A Multicenter Non-interventional Study to Observe the Safety and Efficacy of Etanercept (Enbrelr) in Patients With Moderately Active Rheumatoid Arthritis in Every Day Clinical Practice in Austria.
non-intervention

Rheumatoid Arthritis Clinical Trial using Rituximab

Biocad - Recruiting 18 years to 80 years.
- Double Blind Randomized Clinical Study Evaluating Efficacy and Safety of BCD-020 and MabThera in Patients With Rheumatoid Arthritis Who Had an Inadequate Response or Intolerance to Other DMARDs Including One or More TNF Inhibitor Therapies.
Rituximab

Osteoarthritis,, Rheumatoid Arthritis,, Traumatic Arthritis,, or Clinical Trial using Zimmer Persona Total Knee System

Zimmer, Inc. - Recruiting 18 years to 75 years.
- Persona Outcomes Led Assessment Research in Total Knee Arthroplasty.
Zimmer Persona Total Knee System

Rheumatoid Arthritis Clinical Trial using Adalimumab

Universit‚ de Sherbrooke - Recruiting 18 years or older.
- Bone Resorption, Osteoclastogenesis and Adalimumab.
Adalimumab

Rheumatoid Arthritis Clinical Trial using Tregalizumab; Placebo

Biotest - Recruiting 18 years to 75 years.
- A 24-week Phase IIb, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Investigate the Efficacy and Safety of Tregalizumab (BT061) in Combination With Methotrexate in the Treatment of Subjects With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate Alone, Followed by a 24-week Extension Phase: T Cell REgulating Arthritis Trial 2b (TREAT 2b).
Tregalizumab; Placebo

Rheumatoid Arthritis Clinical Trial using Health Log

Brigham and Women's Hospital - Recruiting 18 years or older.
- The Use of a Health Management Tool in a Clinic Setting to Improve Self-Efficacy in Rheumatoid Arthritis Patients: a Randomized Clinical Trial..
Health Log

Arthritis, Rheumatoid, Spondylitis, Ankylosing, or Arthritis, Pso Clinical Trial

Janssen Inc. - Recruiting N/A or older.
- BioTRAC (BIOLOGIC TREATMENT REGISTRY ACROSS CANADA) Rheumatology (Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis).

Rheumatoid Arthritis Clinical Trial

Brigham and Women's Hospital - Recruiting 18 years or older.
- Brigham and Women's Rheumatoid Arthritis Sequential Study.

Rheumatoid Arthritis Clinical Trial using Peer Support Program

Brigham and Women's Hospital - Recruiting 18 years or older.
- Rheumatoid Arthritis Patient-to-Patient Connection Program.
Peer Support Program

Arthritis, Juvenile Rheumatoid Clinical Trial

AbbVie - Recruiting N/A or older.
- Special Investigation (All Case Survey) in Patients With Juvenile Idiopathic Arthritis.

Postmenopausal, Osteopenia, Rheumatoid Arthritis, or Osteoporosis Clinical Trial using Etanercept; Denosumab

Amgen - Recruiting 45 years to 80 years.
- The Effects of Denosumab on the Pharmacokinetics of Etanercept in Postmenopausal Women With Low Bone Mineral Density and Rheumatoid Arthritis.
Etanercept; Denosumab

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 16 years or older.
- Special Investigation in Japanese Rheumatoid Arthritis Patients Who Have no Previous Use of DMARDs and Biological Agents.

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 16 years or older.
- Special Investigation in Patients With Rheumatoid Arthritis (Combo Study : Adalimumab With High Dose MTX).

Rheumatoid Arthritis Clinical Trial using Adrenocorticotropic Hormone Gel (ACTH)

University of Pittsburgh - Recruiting 18 years or older.
- Open Label Study to Evaluate Efficacy and Safety of Short-Term, Adjunctive Adrenocorticotropic Hormone (ACTH) Gel in Rheumatoid Arthritis.
Adrenocorticotropic Hormone Gel (ACTH)

Degenerative Arthritis, Post-Traumatic Arthritis, or Rheumatoid A Clinical Trial using Carbon Modular Radial Head; Metal Radial Head

Ascension Orthopedics, Inc. - Recruiting 18 years to 85 years.
- Safety and Effectiveness Study of Ascension's PyroCarbon Radial Head Compared to Ascension's Metal Radial Head to Treat Arthritis, Fractures of the Radial Head, Relief of Symptoms After Radial Head Resection, or Revision of a Failed Radial Head Implant..
Carbon Modular Radial Head; Metal Radial Head

Rheumatoid Arthritis Clinical Trial using sarilumab SAR153191 (REGN88); simvastatin

Sanofi - Recruiting 18 years to 75 years.
- A Multi-center, Open-label, 2-treatment, Single-sequence Clinical Study to Evaluate the Effects of a Single 200 mg Subcutaneous Injection of Sarilumab on the Pharmacokinetics of a Single 40 mg Oral Dose of Simvastatin, With Optional 1-year Extension of Open Label Treatment of Sarilumab, in Patients With Rheumatoid Arthritis.
sarilumab SAR153191 (REGN88); simvastatin

Shoulder Arthritis Osteoarthritis, Rheumatoid Arthritis Shoulder, Clinical Trial using Ascension HRA device

Ascension Orthopedics, Inc. - Recruiting 18 years to 75 years.
- Ascensionr Humeral Resurfacing Arthroplasty Follow-Up Study.
Ascension HRA device

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 18 years or older.
- Physical ACtivity in patiEnts With Rheumatoid Arthritis Treated With Adalimumab in Routine Clinical Practice (PACE).

Rheumatoid Arthritis, Ankylosing Spondylitis, or Psoriatic Arthri Clinical Trial

AbbVie - Recruiting 18 years or older.
- Assessment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Patient`s Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice.

Rheumatoid Arthritis, or Crohn's Disease Clinical Trial

UCB, Inc. - Recruiting 18 years or older.
- Observational Study to Evaluate the Safety and Effectiveness of Cimzia in Rheumatoid Arthritis and Crohn's Disease Patients When Using a Comprehensive Program of Tuberculosis Screening and Monitoring.

Rheumatoid Arthritis Clinical Trial using Decision Support Tool; Usual Care

Geisinger Clinic - Recruiting 18 years or older.
- 'Learning About Biologics'.
Decision Support Tool; Usual Care

Rheumatoid Arthritis Clinical Trial using Secukinumab (AIN457)

Novartis - Recruiting 18 years or older.
- A Three Year Extension Study to Evaluate the Long Term Efficacy, Safety and Tolerability of Secukinumab in Subjects With Active Rheumatoid Arthritis.
Secukinumab (AIN457)

Rheumatoid Arthritis Clinical Trial using CC-292; Placebo

Celgene Corporation - Recruiting 18 years to 80 years.
- A Phase 2a, 4-Week Double-Blind, Proof-of-Concept Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid Arthritis.
CC-292; Placebo

Rheumatoid Arthritis Clinical Trial using Exercise

Capital District Health Authority, Canada - Recruiting 20 years to 75 years.
- The Effects of a 12-week Cardiovascular Rehabilitation Exercise Program on Inflammatory Markers and Traditional Coronary Artery Disease Risk Factors in Patients With Rheumatoid Arthritis.
Exercise

Rheumatoid Arthritis Clinical Trial using Iguratimod; Methotrexate

Jiangsu Simcere Pharmaceutical Co., Ltd. - Recruiting 18 years to 65 years.
- A Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Iguratimod Alone or Iguratimod in Combination With Methotrexate Versus Methotrexate Alone in Patients With Rheumatoid Arthritis.
Iguratimod; Methotrexate

Arthritis, Osteoarthritis, Chondrocalcinosis, Gouty Arthritis, or Clinical Trial

Centre Hospitalier Universitaire de Nice - Recruiting N/A or older.
- Study of the Role of Acid Sensing Ion Channels (ASICs) in Human Inflammatory Pain.

Rheumatoid Arthritis Clinical Trial using Neuromuscular electrical stimulation; Volitional exercises

University of Pittsburgh - Recruiting 21 years or older.
- The Use of Neuromuscular Electrical Stimulation to Reverse Muscle Atrophy in Patients With Rheumatoid Arthritis.
Neuromuscular electrical stimulation; Volitional exercises

Rheumatoid Arthritis Clinical Trial using Certolizumab

University of Rochester - Recruiting 18 years or older.
- The Effect of Certolizumab on Lower Extremity Lymph Flow in Rheumatoid Arthritis.
Certolizumab

Rheumatoid Arthritis Clinical Trial using leflunomide; methotrexate

Shanxi Medical University - Recruiting 18 years to 75 years.
- A 48-week, Multi-center, Randomized, Open-lable, Controlled Study to Assess the Response (ACR20) Using Different Disease-Modifying Antirheumatic Drugs Cycle Combination Regimen in Adult Patients With Active Rheumatoid Arthritis.
leflunomide; methotrexate

Rheumatoid Arthritis Clinical Trial using insoles intervention; placebo insole

Federal University of Sao Paulo - Recruiting 18 years to 65 years.
- Effect of Rheumatoid Foot Insole.
insoles intervention; placebo insole

Lupus Erythematosus, Systemic, or Arthritis, Rheumatoid Clinical Trial

Federal University of Sao Paulo - Recruiting 18 years to 60 years.
- Ultrasound Evaluation of Hands in Patients With Systemic Lupus Erythematosus.

Rheumatoid Arthritis, Pregnancy, TNFalfa Inhibitors, Preconceptio Clinical Trial

Erasmus Medical Center - Recruiting 18 years to 45 years.
- Preconception Counselling for Women With a Pregnancy Wish and High Disease Activity of Rheumatoid Arthritis (RA) With a Prospective Observational Study Addressing Health Issues of Mother and Child..

Rheumatoid Arthritis Clinical Trial using Open Label Drug Certolizumab Pegol (CZP); Arthroscopic synovial tissue biopsy

Arthritis Treatment Center, Maryland - Recruiting 18 years or older.
- Open-Label Pre and Post Treatment Arthroscopic Synovial Biopsy Study for the Assessment of Certolizumab Pegol Immunomodulatory Synovial Effects on Select Biomarkers and Gene Expression.
Open Label Drug Certolizumab Pegol (CZP); Arthroscopic synovial tissue biopsy

Rheumatoid Arthritis Clinical Trial

PerCuro Clinical Research Ltd - Recruiting 19 years or older.
- A Phase IV, Post-marketing, Observational Study of Rituxan in Rheumatoid Arthritis Patients in Routine Clinical Practice.

Juvenile Rheumatoid Arthritis Clinical Trial

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Recruiting N/A or older.
- Research Registry for Juvenile Arthritis.

Rheumatoid Arthritis Clinical Trial

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Recruiting 19 years or older.
- Consortium for the Longitudinal Evaluation of African-Americans With Early Rheumatoid Arthritis (CLEAR) Registry.

Rheumatoid Arthritis, or Arthritis Clinical Trial using Adalimumab; Methotrexate

Goupe d'Etudes et de Recherche Clinique En Rhumatologie - Recruiting 18 years or older.
- Methotrexate Alone Versus Methotrexate in Combination With Adalimumab in Early Arthritis.
Adalimumab; Methotrexate