138 results found.

Infant, Premature, Bronchopulmonary Dysplasia, or Asthma Clinical Trial

Indiana University - Recruiting 2 Months to 24 Months.
- Growth of Airways and Lung Parenchyma.

Rhinitis, Allergic, Perennial, or Rhinitis, Allergic, Nonseasonal Clinical Trial using MK-8237 tablets; Placebo tablets; Rescue Medication: Self-Injectable Epinephrine; Rescue Medication: Loratadine tablets; Rescue Medication: Olopatadine ophthalmic drops; Rescue Medication: Mometasone furoate nasal spray

Merck Sharp & Dohme Corp. - Recruiting 12 years or older.
- A One-year Placebo-Controlled Study Evaluating the Efficacy and Safety of the House Dust Mite Sublingual Allergen Immunotherapy Tablet (SCH 900237/MK 8237) in Children and Adult Subjects With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma (Protocol No. P05607/001-00).
MK-8237 tablets; Placebo tablets; Rescue Medication: Self-Injectable Epinephrine; Rescue Medication: Loratadine tablets; Rescue Medication: Olopatadine ophthalmic drops; Rescue Medication: Mometasone furoate nasal spray

Asthma Clinical Trial using MK-1029 10 mg; MK-1029 30 mg; MK-1029 150 mg; Montelukast 10 mg; Placebo; MK-1029 1 mg or 3 mg; Montelukast 10 mg + MK-1029

Merck Sharp & Dohme Corp. - Recruiting 18 years to 65 years.
- A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Parallel-Group, Adaptive-Design, Dose-Ranging Study of MK-1029 in Adult Subjects With Persistent Asthma.
MK-1029 10 mg; MK-1029 30 mg; MK-1029 150 mg; Montelukast 10 mg; Placebo; MK-1029 1 mg or 3 mg; Montelukast 10 mg + MK-1029

Hereditary Angioedema Clinical Trial using icatibant

Shire Development LLC - Recruiting 2 years to 17 years.
- A Multicenter, Open-Label, Non-Randomized Study to Assess the Pharmacokinetics, Tolerability, and Safety of a Single Subcutaneous Administration of Icatibant in Children and Adolescents With Hereditary Angioedema.
icatibant

Cryopyrin-associated Periodic Syndromes (CAPS), Familial Cold Aut Clinical Trial

Novartis - Recruiting N/A or older.
- An Open-label, Long-term, Prospective, Observational Study to Monitor the Safety and Effectiveness of Ilaris in CAPS Patients.

Asthma Clinical Trial using Tiotropium low dose QD; Tiotropium high dose QD; Placebo

Boehringer Ingelheim - Recruiting 6 years to 11 years.
- A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate Efficacy and Safety of Tiotropium Inhalation Solution (2.5 mcg and 5 mcg) Delivered Via Respimatr Inhaler Once Daily in the Evening Over 48 Weeks in Children (6 to 11 Years Old) With Moderate Persistent Asthma.
Tiotropium low dose QD; Tiotropium high dose QD; Placebo

Asthma Clinical Trial using tiotropium-bromide; placebo

Boehringer Ingelheim - Recruiting 1 year to 5 years.
- A Phase II/III, Randomised, Double-blind, Placebo-controlled, Parallel Group Trial to Evaluate Safety and Efficacy of Tiotropium Inhalation Solution (2.5 æg and 5 æg) Administered Once Daily in the Afternoon Via Respimatr Inhaler for 12 Weeks in Patients 1 to 5 Years Old With Persistent Asthma.
tiotropium-bromide; placebo

Asthma Clinical Trial using Placebo; 210 mg brodalumab

Amgen - Recruiting 18 years to 75 years.
- A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Brodalumab in Subjects With Inadequately Controlled Asthma and High Bronchodilator Reversibility.
Placebo; 210 mg brodalumab

Asthma Clinical Trial using Placebo; Tiotropium low dose mcg; Tiotropium high dose

Boehringer Ingelheim - Recruiting 6 years to 11 years.
- A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate Efficacy and Safety of Tiotropium Inhalation Solution (2.5 mcg and 5 mcg) Delivered Via Respimat® Inhaler Once Daily in the Evening Over 12 Weeks as add-on Controller Therapy on Top of Usual Care in Children (6 to 11 Years Old) With Severe Persistent Asthma.
Placebo; Tiotropium low dose mcg; Tiotropium high dose

Asthma Clinical Trial using Standard nebulizer; PARI LC Sprint Sp nebulizer

Centre Hospitalier Universitaire de NÄ«mes - Recruiting 6 Months to 36 Months.
- Efficacy of the PARI LC Sprint Sp Nebulizer for Acute Asthma Attack in Hospitalized Children Less Than 36 Months of Age.
Standard nebulizer; PARI LC Sprint Sp nebulizer

Healthy Volunteers and Asthma Clinical Trial using CNTO 3157 (healthy participants); Placebo (healthy participants); CNTO 3157 (asthmatic patients); Placebo (asthmatic patients); HRV-16

Janssen Research & Development, LLC - Recruiting 18 years to 65 years.
- A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating CNTO 3157 in Healthy Normal and Asthmatic Subjects Inoculated With Human Rhinovirus Type 16.
CNTO 3157 (healthy participants); Placebo (healthy participants); CNTO 3157 (asthmatic patients); Placebo (asthmatic patients); HRV-16

Severe Asthma Clinical Trial using Alair System

Asthmatx, Inc. - Recruiting 18 years to 65 years.
- Post-FDA Approval Clinical Trial Evaluating Bronchial Thermoplasty in Severe Persistent Asthma.
Alair System

Asthma Clinical Trial using Lebrikizumab; Placebo

Hoffmann-La Roche - Recruiting 12 years to 75 years.
- A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, MULTICENTER TRIAL TO ASSESS THE ORAL CORTICOSTEROID-SPARING EFFECT OF LEBRIKIZUMAB IN PATIENTS WITH SEVERE CORTICOSTEROID-DEPENDENT ASTHMA.
Lebrikizumab; Placebo

Asthma Clinical Trial

Hoffmann-La Roche - Recruiting 12 years or older.
- A Prospective Observational Study To Evaluate Predictors of Clinical Response To Omalizumab.

Asthma Clinical Trial using Beclomethasone dipropionate; Placebo; Albuterol/salbutamol

Teva Pharmaceutical Industries - Recruiting 12 years or older.
- A Randomized, Double-Blind, Double-Dummy, Placebo Controlled, Parallel-Group, 12-Week Clinical Study to Assess the Efficacy and Safety of 320 or 640 mcg/Day of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma.
Beclomethasone dipropionate; Placebo; Albuterol/salbutamol

Asthma Clinical Trial using lebrikizumab; placebo

Hoffmann-La Roche - Recruiting 18 years to 75 years.
- A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication.
lebrikizumab; placebo

Asthma Clinical Trial using corticosteroids; prednisolone; LABA

Hoffmann-La Roche - Recruiting 12 years to 75 years.
- A STUDY TO MEASURE SERUM PERIOSTIN, ASTHMA-RELATED BIOMARKERS AND RESPONSE TO PREDNISOLONE IN ADULT AND ADOLESCENT PATIENTS WITH SEVERE ORAL CORTICOSTEROID-DEPENDENT ASTHMA.
corticosteroids; prednisolone; LABA

Asthma Clinical Trial using Budesonide/Formoterol SPIROMAXr; SYMBICORTr TURBOHALERr

Teva Pharmaceutical Industries - Recruiting 12 years or older.
- A 12-Week Efficacy and Safety Evaluation of Budesonidel/Formoterol SPIROMAXr 160/4.5 mcg Inhalation Powder Versus SYMBICORTr TURBOHALERr 200/6 mcg in Adult and Adolescent Patients With Persistent Asthma.
Budesonide/Formoterol SPIROMAXr; SYMBICORTr TURBOHALERr

Asthma Clinical Trial using Beclomethasone dipropionate; Placebo; albuterol/salbutamol 90 mcg

Teva Pharmaceutical Industries - Recruiting 5 years to 11 years.
- A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Parallel-Group, 12-Week Clinical Study to Assess the Efficacy and Safety of 80 or 160 mcg/Day of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Pediatric Patients 5 Through 11 Years of Age With Persistent Asthma.
Beclomethasone dipropionate; Placebo; albuterol/salbutamol 90 mcg

Persistent Asthma Clinical Trial using Beclomethasone dipropionate breath-actuated inhaler; Placebo breath-actuated inhaler; albuterol/salbutamol

Teva Pharmaceutical Industries - Recruiting 12 years or older.
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 12-Week Clinical Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate (80 and 160 mcg/Day) Delivered Via Breath-Actuated Inhaler (BAI) in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma.
Beclomethasone dipropionate breath-actuated inhaler; Placebo breath-actuated inhaler; albuterol/salbutamol

Eosinophilic Asthma Clinical Trial using Reslizumab; Placebo

Teva Pharmaceutical Industries - Recruiting 12 years to 75 years.
- A 12-Month, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma.
Reslizumab; Placebo

Childhood Asthma, or Allergy Clinical Trial using Ventilation; Placebo Ventilation

University of Aarhus - Recruiting 5 years to 18 years.
- AsthmaVent - Effect of Mechanical Ventilation on Asthma Control in Children.
Ventilation; Placebo Ventilation

Asthma, or Pulmonary Fibrosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- Bronchoscopy in Patients With Pulmonary Diseases and Research Volunteers.

Pulmonary Disease, Oropharyngeal Disease, Lymphangioleiomyomatosi Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Role of Helicobacter Pylori and Its Toxins in Pulmonary and Oropharyngeal Disease.

Uncontrolled and Persistent Asthma Clinical Trial using Phase IIb formulation; Putative phase III formulation; Slow dissolution variant 1; Slow dissolution variant 2; Test treatment E

AstraZeneca - Recruiting 18 years to 50 years.
- An Open-label, Single Centre Relative Bioavailability Study With an Adaptive Design Comparing up to 5 Solid Oral AZD5069 Formulations After Single Dose Administration to Healthy Volunteers.
Phase IIb formulation; Putative phase III formulation; Slow dissolution variant 1; Slow dissolution variant 2; Test treatment E

Asthma, or COPD Clinical Trial

Medical University of Warsaw - Recruiting 18 years to 90 years.
- Relationship Between Airway Inflammation and Remodeling in Asthma and COPD Patients..

Asthma Clinical Trial using Benralizumab; Placebo

AstraZeneca - Recruiting 18 years to 75 years.
- A Multicentre, Randomized, Double-blind, Parallel Group, Placebo-controlled, Phase III Efficacy and Safety Study of Benralizumab (MEDI-563) Added to Medium-dose Inhaled Corticosteroid Plus Long-acting á2 Agonist in Patients With Uncontrolled Asthma.
Benralizumab; Placebo

Ankylosing Spondylitis Clinical Trial using Tofacitinib 2 mg; Tofacitinib 5 mg; Tofacitinib 10 mg; Placebo

Pfizer - Recruiting 18 years or older.
- A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study Of The Efficacy And Safety Of Tofacitinib In Subjects With Active Ankylosing Spondylitis (AS).
Tofacitinib 2 mg; Tofacitinib 5 mg; Tofacitinib 10 mg; Placebo

Respiratory Syncytial Virus, or Asthma Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 60 years.
- The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection.

Asthma Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Longitudinal Observational Study of Severe Asthma.

Asthma, Eosinophilia, Helminthiasis, Hypersensitivity, or Parasit Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 1 year or older.
- Eosinophil Activation and Function in Parasitic Infections and Other Conditions With Increased Tissue or Peripheral Blood Eosinophilia in Humans.

Persistent Asthma Clinical Trial using Formoterol; Fluticasone propionate 100 mcg; Fluticasone propionate 250 mcg; Fluticasone propionate 500 mcg; Placebo

Novartis - Recruiting 12 years or older.
- A 26 Week, Randomized, Active-controlled Safety Study of Double-blind Formoterol Fumarate in Free Combination With an Inhaled Corticosteroid Versus an Inhaled Corticosteroid in Adolescent and Adult Patients With Persistent Asthma..
Formoterol; Fluticasone propionate 100 mcg; Fluticasone propionate 250 mcg; Fluticasone propionate 500 mcg; Placebo

Asthma, Diabetes, Obesity, Premature Birth, or Autistic Disorder Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Vanguard Phase of the National Children s Study.

Asthma Clinical Trial using dupilumab SAR231893 (REGN668); placebo

Sanofi - Recruiting 18 years or older.
- A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma.
dupilumab SAR231893 (REGN668); placebo

Asthma, or Severe Persistent Asthma Clinical Trial using Triamcinolone Acetonide

University of Pittsburgh - Recruiting 6 years or older.
- Implications and Stability of Clinical and Molecular Phenotypes of Severe Asthma.
Triamcinolone Acetonide

ASTHMA Clinical Trial using Exhaled breath temperature

Fundaci¢ Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau - Recruiting 18 years or older.
- EXHALED AIR TEMPERATURE (TAE) AS A MARKER OF AIRWAY INFLAMMATION IN ASTHMA.
Exhaled breath temperature

Asthma Clinical Trial using ADVAIR 100/50mcg; ADVAIR 250/50mcg; FLOVENT 100mcg; FLOVENT 250mcg

GlaxoSmithKline - Recruiting 4 years to 11 years.
- A 6-month Safety and Benefit Study of Inhaled Fluticasone Propionate/ Salmeterol Combination Versus Inhaled Fluticasone Propionate in the Treatment of 6,200 Pediatric Subjects 4-11 Years Old With Persistent Asthma.
ADVAIR 100/50mcg; ADVAIR 250/50mcg; FLOVENT 100mcg; FLOVENT 250mcg

Asthma Clinical Trial using Pictogram-based asthma action plan

New York University School of Medicine - Recruiting N/A or older.
- Improving Parent Understanding of Instructions About Asthma Care.
Pictogram-based asthma action plan

Asthma Clinical Trial using Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 25 mcg; Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 50 mcg; Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg; Mometasone Furoate (MF) Dry Powder Inhaler (DPI), 100 mcg; Placebo Metered Dose Inhaler (MDI); Placebo Dry Powder Inhaler (DPI)

Merck Sharp & Dohme Corp. - Recruiting 5 years to 11 years.
- A 12-Week, Randomized, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study of Mometasone Furoate Metered Dose Inhaler in the Treatment of Children Ages 5 to 11 Years With Persistent Asthma.
Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 25 mcg; Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 50 mcg; Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg; Mometasone Furoate (MF) Dry Powder Inhaler (DPI), 100 mcg; Placebo Metered Dose Inhaler (MDI); Placebo Dry Powder Inhaler (DPI)

Asthma Clinical Trial using Benralizumab; Placebo

AstraZeneca - Recruiting 18 years to 75 years.
- A Multicentre, Randomized, Double-blind, Parallel Group, Placebo-controlled, Phase III Efficacy and Safety Study of Benralizumab (MEDI-563) Added to High-dose Inhaled Corticosteroid Plus Long-acting á2 Agonist in Patients With Uncontrolled Asthma.
Benralizumab; Placebo

Asthma Clinical Trial using inspiratory muscle training

University of Portsmouth - Recruiting 18 years to 59 years.
- Inspiratory Muscle Training as a Novel Approach in the Treatment of Asthma.
inspiratory muscle training

Asthma Clinical Trial using Benralizumab; Placebo

AstraZeneca - Recruiting 18 years to 75 years.
- A Multicentre, Randomized, Double-blind, Parallel Group, Placebo-controlled, Phase III Efficacy and Safety Study of Benralizumab (MEDI-563) Added to High-dose Inhaled Corticosteroid Plus Long-acting á2 Agonist in Patients With Uncontrolled Asthma (CALIMA).
Benralizumab; Placebo

Asthma Clinical Trial using Qvarr (beclometasone dipropionate HFA)

University of Dundee - Recruiting 18 years to 65 years.
- Targeted Small Airways Therapy in Persistent Asthma.
Qvarr (beclometasone dipropionate HFA)

Seasonal Allergic Rhinitis, or Asthma Clinical Trial using Ragweed-SPIRE; Placebo

Circassia Limited - Recruiting 18 years to 65 years.
- A Multi-Centre, Double-Blind, Randomised, Placebo-Controlled Parallel-Group Study to Assess the Safety and Tolerability of Ragweed-SPIRE in Subjects With Asthma and Ragweed-Induced Rhinoconjunctivitis.
Ragweed-SPIRE; Placebo

Asthma Clinical Trial using AMG 282; AMG 282 Matching Placebo

Amgen - Recruiting 18 years to 45 years.
- A Randomized, Double-Blind, Placebo-controlled, Ascending, Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Mild Atopic Asthma.
AMG 282; AMG 282 Matching Placebo

Psoriasis Clinical Trial using CP-690,550

Pfizer - Recruiting 18 years or older.
- A Phase 3, Multi-Site, Open-Label Study Of The Long Term Safety And Tolerability Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis.
CP-690,550

Asthma Clinical Trial using RV16UB

Merck Sharp & Dohme Corp. - Recruiting 18 years to 55 years.
- A Dose-Finding and Longitudinal Biomarker Study of Rhinovirus Challenge in Healthy Volunteers and Mild-Moderate Asthmatics to Evaluate the Safety and Use of a Human Rhinovirus Preparation in Developing High Dimensionality Phenotypes ('Handprints') for Asthma.
RV16UB

Asthma, or Obstructive Sleep Apnea Clinical Trial using FDA-Approved Treatment

University of Wisconsin, Madison - Recruiting 18 years to 73 years.
- The Relationship Between Asthma and Obstructive Sleep Apnea (OSA) - A Pilot Study of the Effects of OSA and Its Treatment on Asthma.
FDA-Approved Treatment

Asthma Clinical Trial

University of Wisconsin, Madison - Recruiting 6 years or older.
- Severe Asthma Research Program (SARP) - University of Wisconsin.

Asthma Clinical Trial using Segmental Allergen Challenge

University of Wisconsin, Madison - Recruiting 18 years to 50 years.
- Functional Activity of Airway Eosinophils in Allergic Disease.
Segmental Allergen Challenge

Seasonal Allergic Rhinitis Clinical Trial using acupressure pellets

University of Mississippi Medical Center - Recruiting 18 years or older.
- Pilot Study to Evaluate Ear Acupressure Effects in Treating Seasonal Allergic Rhinitis.
acupressure pellets

Asthma Clinical Trial

Milton S. Hershey Medical Center - Recruiting 6 years or older.
- Severe Asthma Research Program.

Asthma Clinical Trial using Flovent Diskusr 100 mcg; Flovent Diskusr 250 mcg; Flovent Diskusr 500 mcg; Advair Diskusr 100/50 mcg; Advair Diskusr 250/50 mcg

Milton S. Hershey Medical Center - Recruiting 5 years or older.
- Best African American Response to Asthma Drugs.
Flovent Diskusr 100 mcg; Flovent Diskusr 250 mcg; Flovent Diskusr 500 mcg; Advair Diskusr 100/50 mcg; Advair Diskusr 250/50 mcg

Asthma Clinical Trial using Placebo; JNJ-38518168

Janssen Research & Development, LLC - Recruiting 18 years to 75 years.
- A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel Group Study of JNJ-38518168 in Symptomatic Adult Subjects With Uncontrolled, Persistent Asthma.
Placebo; JNJ-38518168

Asthma,, or Pulmonary Disease, Chronic Obstructive Clinical Trial using Medical tests

Janssen Research & Development, LLC - Recruiting 18 years to 70 years.
- A Multicenter Longitudinal Study for Disease Profiling of Asthma and Chronic Obstructive Pulmonary Disease.
Medical tests

Asthma Clinical Trial using no intervention

University of South Florida - Recruiting 5 years to 85 years.
- Identification of Plasma miRNAs as Potential Biomarkers in Asthma Exacerbation.
no intervention

Asthma Clinical Trial using Fluticasone, Budesonide, Beclomethasone; Fluticasone, Beclomethasone, Budesonide; Budesonide, Fluticasone, Beclomethasone; Budesonide, Beclomethasone, Fluticasone; Beclomethasone, Fluticasone, Budesonide; Beclomethasone, Budesonide, Fluticasone

West Penn Allegheny Health System - Recruiting 6 years to 11 years.
- A Randomized, Cross Over Study Evaluating the Effect of Flovent Discus 100 mcg BID vs QVAR 80 mcg BID vs Pulmicort Flexhaler 180 mcg BID on Short Term Growth in Pediatric Subjects With Asthma.
Fluticasone, Budesonide, Beclomethasone; Fluticasone, Beclomethasone, Budesonide; Budesonide, Fluticasone, Beclomethasone; Budesonide, Beclomethasone, Fluticasone; Beclomethasone, Fluticasone, Budesonide; Beclomethasone, Budesonide, Fluticasone

Asthma, or Allergic Rhinitis Clinical Trial using Alvesco/Omnaris, QVAR/Beconase, Placebo/Placebo; Alvesco/Omnaris, Placebo/Placebo, QVAR/Beconase; QVAR/Beconase, Alvesco/Omnaris, Placebo/Placebo; QVAR/Beconase, Placebo/Placebo, Alvesco/Omnaris; Placebo/Placebo, Alvesco/Omnaris, QVAR/Beconase; Placebo/Placebo, QVAR/Beconase, Alvesco/Omnaris

West Penn Allegheny Health System - Recruiting 12 years to 15 years.
- A Study Evaluating the Effect of Omnaris Nasal Spray 200 mcg QD & Alvesco Inhalation Aerosol 80 BID vs Beconase AQ Nasal Spray 168 mcg BID & QVAR Inhalation Aerosol 40 mcg BID vs Placebo Nasal Spray QD & Placebo Inhalation Aerosol BID on Short Term Growth in Pediatric Subjects With Mild Asthma & Allergic Rhinitis.
Alvesco/Omnaris, QVAR/Beconase, Placebo/Placebo; Alvesco/Omnaris, Placebo/Placebo, QVAR/Beconase; QVAR/Beconase, Alvesco/Omnaris, Placebo/Placebo; QVAR/Beconase, Placebo/Placebo, Alvesco/Omnaris; Placebo/Placebo, Alvesco/Omnaris, QVAR/Beconase; Placebo/Placebo, QVAR/Beconase, Alvesco/Omnaris

Asthma Clinical Trial

The Cleveland Clinic - Recruiting 6 years to 80 years.
- Severe Asthma Research Program.

Asthma, Allergic Asthma, or Non-allergic Asthma Clinical Trial using Allergen

The Cleveland Clinic - Recruiting 18 years to 65 years.
- Asthma Inflammation Research.
Allergen

Asthma, or Vitamin D Deficiency Clinical Trial using Vitamin D2 + vitamin D3; Vitamin D3

Nationwide Children's Hospital - Recruiting 8 years to 17 years.
- Prospective Open Pilot of Low vs. Higher Dose Vitamin D in D-deficient Asthmatic Children: Does Diet Predict Immune Function and Asthma Symptom Response to Vitamin D Supplementation?.
Vitamin D2 + vitamin D3; Vitamin D3

Chronic Idiopathic Urticaria Clinical Trial using AZD1981; Placebo

Johns Hopkins University - Recruiting 18 years to 65 years.
- A Phase IIa, Randomized, Placebo-controlled, Double-blind Study to Assess the Efficacy and Safety of the CRTH2 Antagonist AZD1981 in Patients With Chronic Idiopathic Urticaria (CIU) Who Are Refractory to H1 Antihistamines.
AZD1981; Placebo

Asthma Clinical Trial using Grapefruit juice; Orange Juice; Gatorade

Nemours Children's Clinic - Recruiting 15 years to 18 years.
- Characterization of Transporter Mediated Uptake of Montelukast in Humans.
Grapefruit juice; Orange Juice; Gatorade

Asthma Clinical Trial using Dulera

Asthma Management Systems - Recruiting 18 years or older.
- Improving Asthma Control in the Real World: A Systematic Approach to Improving Dulera Adherence.
Dulera

Asthma Clinical Trial using 10 mg tablet of montelukast (Singulair)

Nemours Children's Clinic - Recruiting 7 years to 35 years.
- Genotype Stratified Pharmacokinetic Study of Montelukast.
10 mg tablet of montelukast (Singulair)

Asthma Clinical Trial using Fluticasone Furoate; Fluticasone Propionate; Placebo

GlaxoSmithKline - Recruiting 5 years to 11 years.
- A Dose-ranging Study of Fluticasone Furoate (FF) Inhalation Powder in Children Aged 5-11 Years With Asthma.
Fluticasone Furoate; Fluticasone Propionate; Placebo

Asthma Clinical Trial using Mometasone Furoate/Formoterol MDI 100/5 mcg; Mometasone Furoate/Formoterol MDI 200/5 mcg; Mometasone Furoate MDI 100 mcg; Mometasone Furoate MDI 200 mcg; Albuterol 90 mcg /salbutamol 100 mcg HFA MDI; Prednisone/prednisolone

Merck Sharp & Dohme Corp. - Recruiting 12 years or older.
- A 26-Week Randomized, Double-Blinded, Active Controlled Study Comparing the Safety of Mometasone Furoate/Formoterol Fumarate MDI Fixed Dose Combination Versus Mometasone Furoate MDI Monotherapy in Adolescents and Adults With Persistent Asthma (Protocol No. P06241 Also Known as P202).
Mometasone Furoate/Formoterol MDI 100/5 mcg; Mometasone Furoate/Formoterol MDI 200/5 mcg; Mometasone Furoate MDI 100 mcg; Mometasone Furoate MDI 200 mcg; Albuterol 90 mcg /salbutamol 100 mcg HFA MDI; Prednisone/prednisolone

Severe IgE-mediated Asthma Clinical Trial using Omalizumab; Budesonide; Formoterol

Novartis - Recruiting 6 years to 55 years.
- Multicentric, Open-label, Randomized, Parallel--group Study to Evaluate the Efficacy and Safety of Omalizumab in a 12- Month Period, in Patients With Severe IgE-mediated Asthma Inadequately Controlled With High Doses of Corticosteroids..
Omalizumab; Budesonide; Formoterol

Asthma Clinical Trial

University of California, San Francisco - Recruiting 18 years to 75 years.
- Mechanisms of Exacerbation of Asthma.

Asthma Clinical Trial

University of California, San Francisco - Recruiting 18 years to 70 years.
- Chitinases and TGFB in Human Asthma.

Asthma Clinical Trial

University of California, San Francisco - Recruiting 18 years or older.
- Characterization of Adult Subjects for Asthmatic Research Studies.

Mild Persistent Asthma, Uncomplicated Clinical Trial using Nadolol; Placebo

Invion, Inc. - Recruiting 18 years to 60 years.
- .
Nadolol; Placebo

Bronchial Asthma Clinical Trial

AstraZeneca - Recruiting N/A or older.
- Symbicort Turbuhaler 30/60 Clinical Experience Investigation for Treatment With Symbicort as Maintenance Therapy and as Needed in Response to Symptoms.

Chronic Sinusitis With or Without Nasal Polyps Clinical Trial using Fluticasone Propionate

Optinose US Inc. - Recruiting 18 years or older.
- A 12-Month Open-Label Multicenter Study Evaluating the Safety of Intranasal Administration of 400 æg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps.
Fluticasone Propionate

Chronic Sinusitis With or Without Nasal Polyps Clinical Trial using Fluticasone Propionate

Optinose US Inc. - Recruiting 18 years or older.
- A 3-Month Open-Label Multicenter Study Evaluating the Safety of Intranasal Administration of 400 æg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps.
Fluticasone Propionate

Asthma Clinical Trial using ADVAIR 100/50mcg; ADVAIR 250/50mcg; ADVAIR 500/50mcg; FLOVENT 100mcg; FLOVENT 250mcg; FLOVENT 500mcg

GlaxoSmithKline - Recruiting 12 years or older.
- SAS115359, a Safety and Efficacy Study of Inhaled Fluticasone Propionate/Salmeterol Combination Versus Inhaled Fluticasone Propionate in the Treatment of Adolescent and Adult Subjects With Asthma.
ADVAIR 100/50mcg; ADVAIR 250/50mcg; ADVAIR 500/50mcg; FLOVENT 100mcg; FLOVENT 250mcg; FLOVENT 500mcg

Psoriasis Clinical Trial using M518101

Maruho North America Inc. - Recruiting 18 years or older.
- An Open-label, Multi-center, Long-term Study to Evaluate the Safety and Efficacy of M518101 in Subjects With Plaque Psoriasis.
M518101

Asthma Clinical Trial using Nursing-driven clinical pathway for management of inpatient asthma

Children's Hospital of Eastern Ontario - Recruiting 2 years to 17 years.
- The Impact of Implementing a Nursing-driven Clinical Pathway for Inpatient Management of Children Admitted to a Tertiary Care Centre With a Diagnosis of Asthma: A Randomized Controlled Trial.
Nursing-driven clinical pathway for management of inpatient asthma

Diabetes, Heart Disease, or Asthma Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Environmental Polymorphisms Registry Health and Exposures Survey.

Asthma, or Healthy Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 75 years.
- Fiberoptic Bronchoscopy in Patients With Asthma.

Severe, Refractory Asthma, Airway Inflammation, or Airflow Obstru Clinical Trial using Pioglitazone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 75 years.
- A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma.
Pioglitazone

Asthma Clinical Trial using Stand Alone Air Cleaner; HVAC Modification

University of California, Davis - Recruiting 6 years to 12 years.
- Benefits of High Efficiency Filtration to Children With Asthma.
Stand Alone Air Cleaner; HVAC Modification

Asthma, Obesity, or Inflammation Clinical Trial using Montelukast; Placebo

North Shore Long Island Jewish Health System - Recruiting 7 years to 17 years.
- The Effect of Montelukast on Asthma Control in Overweight/Obese Early-Onset Asthmatics.
Montelukast; Placebo

Asthma Clinical Trial using Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage

Massachusetts General Hospital - Recruiting 18 years to 50 years.
- Inflammatory Cellular Trafficking in Asthma in Response to Segmental Allergen Challenge.
Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage

Asthma Clinical Trial using Aerobic training; Breathing exercise

Instituto de Investiga‡ao em Imunologia - Recruiting 20 years to 59 years.
- Effect of Aerobic Training on Bronchial Hyperresponsiveness and Systemic Inflammation in Patients With Moderate or Severe Asthma: a Randomized Controlled Trial.
Aerobic training; Breathing exercise

Asthma Clinical Trial using Sulforaphane

University of North Carolina, Chapel Hill - Recruiting 18 years to 50 years.
- Sulforaphane Supplementation in Atopic Asthmatics.
Sulforaphane

Asthma and Allergic Rhinitis Clinical Trial using Montelukast; Montelukast sodium

PharmaKing - Recruiting 20 years to 45 years.
- A Randomized, Open-label, Single-Dose, 2-Treatment, 2-Way, 2-Period Crossover Study to Compare the Safety and the Pharmacokinetic Characteristics of MKT-N2 (Montelukast) and Singulairr (Montelukast Sodium) Tablet 10mg in Healthy Male Korean Subjects.
Montelukast; Montelukast sodium

Pediatric Asthma Clinical Trial using School-Based Telemedicine Enhanced Asthma Management; Enhanced Usual Care

University of Rochester - Recruiting 3 years to 10 years.
- School-Based Telemedicine Enhanced Asthma Management: A Randomized Control Trial Using Novel Technology to Improve Preventive Asthma Care.
School-Based Telemedicine Enhanced Asthma Management; Enhanced Usual Care

Asthma Clinical Trial using Mepolizumab

GlaxoSmithKline - Recruiting 12 years or older.
- MEA115661: A Multi-centre, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic Subjects Who Participated in the MEA115588 or MEA115575 Trials.
Mepolizumab

Allergic Asthma Clinical Trial using Omalizumab; Placebo injection

Johns Hopkins University - Recruiting 18 years to 75 years.
- Predicting the Clinical Response to Omalizumab With Anti-IgE Response or Syk Expression in Basophils.
Omalizumab; Placebo injection

Asthma Clinical Trial using Laninamivir octanoate

Biota Scientific Management Pty Ltd - Recruiting 18 years to 65 years.
- A Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Inhaled Laninamivir Octanoate in Adults With Chronic Asthma.
Laninamivir octanoate

Asthma Clinical Trial

University of North Carolina, Chapel Hill - Recruiting 12 years to 17 years.
- Observational Assessment of Baseline Asthma Control as a Susceptibility Factor for Air Pollution Health Effects in African-American Children With Moderate-severe Asthma (Teen AIRE Study).

Asthma Clinical Trial using Exercise

University of Oulu - Recruiting 16 years to 65 years.
- Effects of Regular Exercise on Physical Fitness, Asthma Control and Quality of Life of Adult Asthmatics.
Exercise

Hypertension, Substance Abuse, Asthma, or Depression Clinical Trial

Yale University - Recruiting 18 years or older.
- Transitions Clinic Network: Linking High-Risk Medicaid Patients From Prison to Community Primary Care.

Asthma Clinical Trial

Ohio State University - Recruiting 18 years or older.
- Inflammatory Mediators and microRNA Analysis in Premenstrual Asthma.

Depression, or Asthma Clinical Trial using Escitalopram; Placebo

University of Texas Southwestern Medical Center - Recruiting 18 years to 70 years.
- Antidepressant Treatment at an Inner City Asthma Clinic.
Escitalopram; Placebo

Asthma Clinical Trial using without interventions

AstraZeneca - Recruiting 18 years or older.
- The Asthma Control Rate Achieved by Budesonide/Formoterol in Clinical Practice in China.
without interventions

Asthma Clinical Trial using ALAIR Catheter. Radiofrequency system.

Fundaci¢ Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau - Recruiting 18 years or older.
- Study of Physiopathological Mechanisms and Results of Treatment With Bronchial Thermoplasty in Severe Asthma.
ALAIR Catheter. Radiofrequency system.

Obesity, Diabetes, Hypertension, or Asthma/COPD With Tobacco Depe Clinical Trial using CHW Goal Support

University of Pennsylvania - Recruiting N/A or older.
- Community Health Worker Support to Help Patients Control Chronic Disease.
CHW Goal Support

Asthma Clinical Trial

Brigham and Women's Hospital - Recruiting 6 years to 60 years.
- ALXR/FPR Mediated Signaling in Severe Asthma (AMSA)-The Severe Asthma Research Program (SARP) III.

Asthma Clinical Trial

Genentech - Recruiting N/A or older.
- The Xolair Pregnancy Registry: An Observational Study of the Use and Safety of Xolair (Omalizumab) During Pregnancy.

Asthma Clinical Trial using Facebook group

Massachusetts General Hospital - Recruiting 14 years to 17 years.
- Implementation of ACT Through Facebook for Teenagers With Asthma.
Facebook group

Asthma Clinical Trial

Children's Hospital Boston - Recruiting 4 years to 15 years.
- Allergens in Inner-City Schools and Childhood Asthma.

Asthma Clinical Trial using Bronchial provocation test

University Medical Centre Groningen - Recruiting 18 years to 65 years.
- Determining the Optimal Dry Powder Adenosine Provocation Test to Assess Small Airways Disease.
Bronchial provocation test

Asthma, or Rhinitis Clinical Trial using regular treatment

Universita di Verona - Recruiting 5 years or older.
- Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis.
regular treatment

Asthma Clinical Trial using Budesonide

University of California, San Francisco - Recruiting 18 years to 70 years.
- Role of miRNAs in Th2-driven Inflammation in Asthma.
Budesonide

Acute Asthma Clinical Trial using Tailored asthma management program; Generic web-based education

Henry Ford Health System - Recruiting 13 years to 19 years.
- Feasibility of an ED-initiated Online Asthma Management Program for Urban Teens (Puff City-ED).
Tailored asthma management program; Generic web-based education

Premature Birth, Bronchopulmonary Dysplasia, or Asthma Clinical Trial

Indiana University - Recruiting 2 Months to 36 Months.
- Assessment of Lung Structure and Function of Infants Born Prematurely.

Asthma, COPD, or Healthy Clinical Trial using HXe MRI lung ventilation

Xemed LLC - Recruiting 21 years to 75 years.
- Study of Hyperpolarized Xenon (MagniXene) in Patients With Obstructive Pulmonary Diseases (Asthma and COPD) to Assess Regional Lung Function by Delineating Regions of Abnormal Lung Ventilation.
HXe MRI lung ventilation

Asthma Clinical Trial

Capital Institute of Pediatrics, China - Recruiting 4 years to 12 years.
- A Prospective Observational Study in a Tertiary Pediatric Hospital in Beijing to Understand the Accuracy of Bronchodilator Response (BDR) in Chinese Controller Naive Asthmatic Children Between the Age of 4~12 Years Old.

Bronchial Asthma, or Allergic Rhinitis Clinical Trial using sublingual house dust mites allergen extract; placebo in sublingual applicator

Medical Universtity of Lodz - Recruiting 6 years to 18 years.
- Assessment of Effectiveness and Safety of Annual Sublingual Immunotherapy in Children With Bronchial Asthma and/or Allergic Rhinitis Allergic to House Dust Mites.
sublingual house dust mites allergen extract; placebo in sublingual applicator

Asthma, or Rhinitis Clinical Trial using Diagnostic tests, medical interview and questionnaires

Universidade do Porto - Recruiting 3 years to 90 years.
- Control and Burden of Asthma and Rhinitis.
Diagnostic tests, medical interview and questionnaires

Asthma Clinical Trial using NIPPV (PALMtop PTV); Volumetric CO2 (NM3); USCOM

Vanderbilt University - Recruiting 2 years to 18 years.
- A Randomized Controlled Trial of Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations.
NIPPV (PALMtop PTV); Volumetric CO2 (NM3); USCOM

Asthma Clinical Trial using Wee Wheezers

Montefiore Medical Center - Recruiting 2 years to 9 years.
- A Randomized Controlled Trial of a Community Health Worker Home-Based Asthma Intervention.
Wee Wheezers

Asthma, or Severe Persistent Asthma Clinical Trial

Wake Forest School of Medicine - Recruiting 6 years or older.
- The Severe Asthma Research Program at Wake Forest University - Longitudinal Phenomics and Genetics of Severe Asthma..

CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA, or HEALTHY SUBJECT Clinical Trial using SALBUTAMOL

Imperial College London - Recruiting 18 years or older.
- Improving Inhaler Treatment and Small Airways Assessment in Chronic Obstructive Pulmonary Disease (COPD).
SALBUTAMOL

Aspirin Sensitive Rhinosinusitis/Asthma Clinical Trial using omalizumab

The Cleveland Clinic - Recruiting 18 years or older.
- A Placebo Controlled, Double-Blind Investigation of the Therapeutic Utility of Xolair (Omalizumab) for Attenuating Aspirin Induced Bronchospasm in Patients With Aspirin Exacerbated Respiratory Disease (AERD) Undergoing Aspirin Desentization.
omalizumab

T Cell Response to Asthma in HIV-infected Patients Before and Aft Clinical Trial using HAART

The HIV Netherlands Australia Thailand Research Collaboration - Recruiting 2 years to 18 years.
- Allergen Specific T Effector and T Regulatory Cell Response to Common Aeroallergens Following Immune Restoration in HIV-infected Children.
HAART

Asthma, Cystic Fibrosis, Chronic Lung Disease, or Pneumonia Clinical Trial

Maastricht University Medical Center - Recruiting 6 years to 18 years.
- Optimising and Standardising Measurements of Inflammatory Markers in Exhaled Breath (EB) and Exhaled Breath Condensate (EBC).

Asthma Clinical Trial using bronchoscopy

Imperial College London - Recruiting 18 years to 60 years.
- Evaluating the Role of Oxidant/Anti-oxidant Balance and the Relationship of Asthma Severity on Airway Smooth Muscle Proliferation, Migration and Cytokine Release..
bronchoscopy

Bronchial Asthma, or Nitric Oxide Clinical Trial

Mahidol University - Recruiting 7 years to 60 years.
- Association Between Fractional Exhaled Nitric Oxide and Asthma Control.

Asthma Clinical Trial

Tel-Aviv Sourasky Medical Center - Recruiting 5 years to 17 years.
- Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis..

Asthma Clinical Trial using Multisystemic Therapy; Home-based, Non-Directive Family Support

National Heart, Lung, and Blood Institute (NHLBI) - Recruiting 12 years to 16 years.
- Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma.
Multisystemic Therapy; Home-based, Non-Directive Family Support

Asthma Clinical Trial

Bispebjerg Hospital - Recruiting 15 years to 19 years.
- Airway Responsiveness and Inflammation in Adolescent Elite Swimmers: a 3-Year Prospective Follow-up Study.

Chronic Obstructive Pulmonary Disease, or Asthma Clinical Trial

Bispebjerg Hospital - Recruiting 18 years or older.
- Trefoil Peptides in Lung Diseases.

Asthma Clinical Trial using BMEC-1217B

Medigreen Biotechnology Corp. - Recruiting 20 years to 40 years.
- A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalating Safety Study of BMEC-1217B, in Healthy Volunteers.
BMEC-1217B

Asthma Clinical Trial using nippv

Postgraduate Institute of Medical Education and Research - Recruiting N/A or older.
- Non Invasive Ventilation in Acute Asthma.
nippv

Asthma Clinical Trial

National Heart, Lung, and Blood Institute (NHLBI) - Recruiting 2 years to 4 years.
- Asthma Surveillance and Education in Preschool Settings.

Chronic Obstructive Pulmonary Disease Clinical Trial

Imperial College London - Recruiting 38 years to 80 years.
- The Effect of Inhaled Mannitol on Ciliary Beat Frequency in COPD Patients.

Asthma Clinical Trial using Pictorial asthma action plan

Children's Mercy Hospital Kansas City - Recruiting 6 years to 18 years.
- Relative Effectiveness of Pictorial and Written Asthma Action Plans for Pediatric Asthma.
Pictorial asthma action plan

Asthma, COPD, or Cough Clinical Trial

National Taiwan University Hospital - Recruiting 18 years or older.
- Association Between Sputum and Plasma Levels of Nociceptin and Substance P With Cough Severity and Airway Hyperreactivity in Patients With Asthma, COPD and Chronic Cough.