Boehringer Ingelheim - Recruiting 18 years or older. - The Comparative Safety and Effectiveness of Warfarin and Dabigatran Utilized in the Department of Defense (DoD) Non-Valvular Atrial Fibrillation (NVAF) Patient Population-A Retrospective Database Analysis.
Boehringer Ingelheim - Recruiting 18 years or older. - A Prospective, Open Label Study Evaluating the Efficacy of Two Management Strategies (Pantoprazole 40 mg q.a.m. and Taking PradaxaÂ® With Food (Within 30 Minutes After a Meal) on Gastrointestinal Symptoms (GIS) in Patients Newly on Treatment With PradaxaÂ® 150 mg b.i.d., 110 mg b.i.d. or 75 mg b.i.d. for the Prevention of Stroke and Systemic Embolism in Patients With Non-valvular Atrial Fibrillation (NVAF).
pantoprazole; Pradaxa (dabigatran etexilate); Pradaxa, within 30 minutes after a meal
Boehringer Ingelheim - Recruiting 19 years or older. - A Regulatory Requirement Non-interventional Study to Monitor the Safety and Effectiveness of Pradaxa (Dabigatran Etexilate Mesilate, 110 mg or 150 mg b.i.d.) in Korean Patients With Non-valvular Atrial Fibrillation(SPARK: Safety Study of Pradaxa in AF Patients by Regulatory Requirement of Korea).
Boehringer Ingelheim - Recruiting 18 years or older. - GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment In PAtients With Atrial Fibrillation (Phase II/III - EU/EEA Member States).
Toray Industries (America), Inc. - Recruiting 18 years or older. - A Pilot Study Evaluating the Safety and Effectiveness of the Toray Satake Balloon Thermal Ablation System for the Treatment of Paroxysmal Atrial Fibrillation.
Medical University of Vienna - Recruiting 18 years to 40 years. - The Effect of Ticagrelor and Apixaban With or Without Acetylsalicylic Acid on Markers of Coagulation Activation at the Site of Thrombus Formation in Vivo in Healthy Male Subjects and in an ex Vivo Perfusion Chamber Model at High and Low Shear Rate.
Bayer - Recruiting 18 years or older. - Belgian Real Life Non-interventional Study (NIS) on XareltoÂ® in Non-valvular Atrial Fibrillation (AF) Patients Treated for the Prevention of Stroke and Systemic Embolism (BOX-AF).
RWTH Aachen University - Recruiting 18 years or older. - Influence of Rivaroxaban Compared to Vitamin K Antagonist Treatment Upon Development of Cardiovascular Calcification in Patients With Atrial Fibrillation and/ or Pulmonary Embolism.
Bayer - Recruiting 18 years or older. - An Open-label, International, Multicenter, Interventional Study Exploring the Efficacy of Once-daily Oral Rivaroxaban (BAY 59-7939) for the Treatment of Left Atrial/Left Atrial Appendage Thrombus in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter.
St. Jude Medical - Recruiting 18 years or older. - A Prospective, Randomized, Multicenter, Interventional Study to Evaluate the Safety and Effectiveness of the TactiCath Percutaneous Ablation Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation Using Contact Force Assisted Radiofrequency Ablation.
Catheter ablation for the treatment of paroxysmal atrial fibrillation
Centre Hospitalier Universitaire de Saint Etienne - Recruiting 18 years or older. - Comparison of Treatment of Atrial Fibrillation (AF) Between Surgical Ultrasonic Technology (EPICOR) or Drug Therapy (Cordarone) for Patients With AF Requiring Mitral Valve Surgery.
Cardioangiologisches Centrum Bethanien - Recruiting 18 years to 80 years. - Catheter Ablation of Drug-refractory Persistent Atrial Fibrillation With the HeartLight(TM) Laser Balloon in Comparison With Irrigated Radiofrequency Current Ablation.
HeartLight(TM) Laser Balloon; irrigated radiofrequency current ablation
Janssen Scientific Affairs, LLC - Recruiting 18 years or older. - An Open-label, Randomized, Controlled, Multicenter Study Exploring Two Treatment Strategies of Rivaroxaban and a Dose-Adjusted Oral Vitamin K Antagonist Treatment Strategy in Subjects With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention.
Bayer - Recruiting 18 years or older. - XANTUS-EL, Xareltor on Prevention of Stroke and Noncentral Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in Eastern EU, Middle East, Africa (EMEA) and Latin America (LATAM): A Noninterventional Study.
Boehringer Ingelheim - Recruiting 18 years or older. - A Prospective, Open Label Study to Evaluate the Pharmacokinetics of Dabigatran in Non-valvular Atrial Fibrillation (NVAF) Patients With Severely Impaired Renal Function on Dabigatran Etexilate 75 mg BID Therapy.
Janssen Scientific Affairs, LLC - Recruiting 18 years or older. - A Randomized, Open-label, Active-controlled Multi-center Study to Assess Safety of Uninterrupted Rivaroxaban vs. Usual Care in Subjects Undergoing Catheter Ablation Therapy for Atrial Fibrillation.
rivaroxaban; uninterrupted vitamin K antagonist (VKA)
Deutsches Herzzentrum Muenchen - Recruiting 18 years or older. - Intracoronary Stenting and Antithrombotic Regimen: Testing of a Six-week Versus a Six-month Clopidogrel Treatment Regimen in Patients With Concomitant Aspirin and Oral Anticoagulant Therapy Following Drug-eluting Stenting.
Bayer - Recruiting 18 years or older. - Xareltor on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in Asia: A Non-interventional Study.
University Hospital, Basel, Switzerland - Recruiting 50 years or older. - Canakinumab for the Prevention of Recurrences After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation (CONVERT-AF) Trial - A Randomized Double Blind Placebo Controlled Study.
Karolinska Institutet - Recruiting 18 years or older. - Observational Prospective Case-control Study on Prevalence and Impact of Subclinical Hyperthyroidism in Patients Undergoing Atrial Fibrillation Ablation.
Medtronic International Trading Sarl - Recruiting 18 years to 75 years. - A Controlled, Prospective, Non-Inferiority, Parallel-Group, Randomised, Interventional, Open, Blinded Outcome Assessment (PROBE-Design), Multi-centre Trial, Comparing Efficacy and Safety of Isolation of the Pulmonary Veins With a Cryoballoon Catheter Versus a Radiofrequency Ablation With a ThermoCool Catheter in Patients With Paroxysmal Atrial Fibrillation.
Electrical isolation of the pulmonary veins; Electrical isolation of pulmonary veins
Meshalkin Research Institute of Pathology of Circulation - Recruiting 18 years to 65 years. - Left Atrium Reduction Versus no Left Atrium Reduction for Patients With Enlarged Left Atria and Persistent or Long Standing Persistent Atrial Fibrillation Undergoing Mitral Valve Surgery.
maze procedure; mitral valve surgery; left atrial reduction
Bayer - Recruiting 18 years or older. - Prospective Multicenter Observational Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients.
Pierre Fabre Medicament - Recruiting 18 years or older. - Efficacy and Safety Study of F373280 for Maintenance of Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation and Chronic Heart Failure. International, Multicentric, Randomised, Double-blind, Placebo Controlled Study..
Odense University Hospital - Recruiting 65 years to 90 years. - Detection of Subclinical Atrial Fibrillation in High Risk Patients (> 65 Years, Hypertension, Diabetes Mellitus) Using Implantable Loop Recorder.
AtriCure, Inc. - Recruiting 18 years to 80 years. - Feasibility Clinical Investigation of a Minimally Invasive Surgically Deployed AtriCure AtriClip Left Atrial Appendage Exclusion System for Stroke Prophylaxis in Patients With Non-Valvular Atrial Fibrillation and in Whom Long Term Oral Anticoagulation Therapy is Medically Contraindicated.
Otsuka Pharmaceutical Development & Commercialization, Inc. - Recruiting 18 years to 85 years. - A Multi-center, Parallel-group, Double-blind, Placebo-controlled, Randomized, Ascending Dose Trial to Determine the Safety, Tolerability, Pharmacokinetics and Efficacy of Intravenous Infusions of OPC-108459 Administered to Subjects With Paroxysmal and Persistent Atrial Fibrillation.
University of Pennsylvania - Recruiting 18 years or older. - Second Randomization Study to Assess Efficacy of Different Ablation Strategies in Achieving Long-Term Arrhythmia Control in Patients With Persistent or Long Standing Persistent Atrial Fibrillation: RASTA XT Study.
Texas Cardiac Arrhythmia Research Foundation - Recruiting 18 years to 75 years. - Effect of Catheter Ablation on the Prevalence, Clinical Manifestation and MRI Findings of Migraine in AF Patients With or Without a Previous History of Migraine.
Texas Cardiac Arrhythmia Research Foundation - Recruiting 18 years or older. - Freedom From Atrial Arrhythmia in Atrial Fibrillation Patients After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation.
Pulmonary vein antrum isolation (PVAI); PVAI plus left atrial posterior wall (LAPW) isolation
The First Hospital of Nanjing Medical University - Recruiting 18 years to 75 years. - Safety and Effectiveness Study of Percutaneous Catheter-based Renal Sympathetic Denervation in Patients With Drug-resistant Hypertension and Symptomatic Atrial Fibrillation.
The First Hospital of Nanjing Medical University - Recruiting 18 years to 75 years. - Safety and Effectiveness Study of Percutaneous Catheter-based Sympathetic Denervation of the Renal Arteries in Patients With Hypertension and Paroxysmal Atrial Fibrillation.
Mount Sinai School of Medicine - Recruiting 18 years or older. - Surgical Ablation Versus No Surgical Ablation for Patients With Persistent or Longstanding Persistent Atrial Fibrillation (AF) Undergoing Mitral Valve Surgery.
Mitral valve surgery with ligation/excision of left atrial appendage with ablation; Mitral valve surgery with ligation/excision of left atrial appendage
Diakron Pharmaceuticals - Recruiting 18 years to 50 years. - A Randomized, Double-blind, Placebo-controlled, Stepwise Study of the Pharmacokinetics (PK), Pharmacodynamics (PD), PK/PD Characteristics and Safety of Multiple Once-daily Oral Dosing of DPOC-4088 in Healthy Young Male Subjects.
Asklepios proresearch - Recruiting 18 years to 75 years. - Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation - Pulmonary Vein Isolation With or Without Ablation of Complex Fragmented Atrial Potentials.
pulmonary vein isolation; pulmonary vein isolation with additional ablation of fragmented potentials
Asklepios proresearch - Recruiting 30 years to 75 years. - Ablation at St. George Hospital - Prospective Randomized Comparison of Manual and Mechanical Remote Robotic Catheter Ablation for Drug-Refractory Atrial Fibrillation.
Pulmonary vein isolation with radiofrequency current
Hadassah Medical Organization - Recruiting 18 years or older. - Warfarin Induction Regimen Based Upon CYP2C9, VKORC1 Factor VII Genotyping, PMR and INR Monitoring, as Compared to the Conventional Regimen: a Prospective Controlled Study.
St. Antonius Hospital - Recruiting 30 years to 70 years. - Atrial Fibrillation: Ablation or Surgical Treatment; A Randomized Study Comparing Non-Pharmacologic Therapy in Patients With Drug-Refractory Atrial Fibrillation.