300 results found.

Breast Cancer, or Neoplasm Metastasis Clinical Trial using Standard supportive care (packed RBC transfusion); epoetin alfa + packed RBC transfusion

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Randomized, Open-label, Multicenter, Phase 3 Study of Epoetin Alfa Plus Standard Supportive Care Versus Standard Supportive Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy.
Standard supportive care (packed RBC transfusion); epoetin alfa + packed RBC transfusion

Extraocular Retinoblastoma Clinical Trial using autologous bone marrow transplantation; autologous hematopoietic stem cell transplantation; in vitro-treated peripheral blood stem cell transplantation; cisplatin; cyclophosphamide; etoposide; filgrastim; carboplatin; vincristine sulfate; thiotepa; radiation therapy

Children's Oncology Group - Recruiting N/A to 10 years.
- A Trial of Intensive Multi-Modality Therapy for Extra-Ocular Retinoblastoma.
autologous bone marrow transplantation; autologous hematopoietic stem cell transplantation; in vitro-treated peripheral blood stem cell transplantation; cisplatin; cyclophosphamide; etoposide; filgrastim; carboplatin; vincristine sulfate; thiotepa; radiation therapy

Prostate Cancer Clinical Trial using Abiraterone Acetate; Prednisone 5 mg twice daily; Prednisone 5 mg once daily; Prednisone 2.5 mg twice daily; Dexamethasone 0.5 mg once daily

Janssen Pharmaceutica N.V., Belgium - Recruiting 18 years or older.
- A Randomized Phase 2 Study Evaluating Abiraterone Acetate With Different Steroid Regimens for Preventing Symptoms Associated With Mineralocorticoid Excess in Asymptomatic, Chemotherapy-naïve and Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients.
Abiraterone Acetate; Prednisone 5 mg twice daily; Prednisone 5 mg once daily; Prednisone 2.5 mg twice daily; Dexamethasone 0.5 mg once daily

Head and Neck Cancer, or Colon Cancer Clinical Trial using Head and neck; Colon

Brown University - Recruiting 18 years or older.
- A Dose Finding Study of Eribulin Mesylate and Cetuximab For Patients With Advanced Head and Neck and Colon Cancer With an Expansion Cohort For Head and Neck Cancer: A Brown University Oncology Research Group Study.
Head and neck; Colon

Metastatic Breast Cancer Clinical Trial using Cisplatin; Metronomic Cyclophosphamide

Centre Jean Perrin - Recruiting 18 years or older.
- .
Cisplatin; Metronomic Cyclophosphamide

Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent S Clinical Trial using soy isoflavones; laboratory biomarker analysis; survey administration

National Cancer Institute (NCI) - Recruiting 19 years to 79 years.
- A Phase II Trial of Preoperative Soy Isoflavone Supplementation and Molecular Markers in the Prevention of Head and Neck Squamous Carcinoma.
soy isoflavones; laboratory biomarker analysis; survey administration

B-cell Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Rec Clinical Trial using fludarabine phosphate; rituximab; total-body irradiation; allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; cyclosporine; mycophenolate mofetil; laboratory biomarker analysis; pharmacological study

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- Nonmyeloablative Conditioning With Pre- and Post-Transplant Rituximab Followed by Related or Unrelated Donor Hematopoietic Cell Transplantation for Patients With Advanced Chronic Lymphocytic Leukemia: A Multi-Center Trial.
fludarabine phosphate; rituximab; total-body irradiation; allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; cyclosporine; mycophenolate mofetil; laboratory biomarker analysis; pharmacological study

Adult Primary Hepatocellular Carcinoma, Localized Unresectable Ad Clinical Trial using sorafenib tosylate; placebo; doxorubicin hydrochloride; doxorubicin-eluting beads; cisplatin; mitomycin C

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Randomized, Double-Blind Trial of Chemoembolization With or Without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients With and Without Vascular Invasion.
sorafenib tosylate; placebo; doxorubicin hydrochloride; doxorubicin-eluting beads; cisplatin; mitomycin C

Advanced Malignancy, Advanced Solid Tumors, Cancer, Oncology, Onc Clinical Trial using AMG 232

Amgen - Recruiting 18 years or older.
- A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 232 in Adult Subjects With Advanced Solid Tumors.
AMG 232

Healthy, no Evidence of Disease Clinical Trial using retinoid 9cUAB30; placebo; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years to 65 years.
- A Randomized, Double-blind, Phase I Dose-escalation Study of the Novel Retinoid 9cUAB30.
retinoid 9cUAB30; placebo; laboratory biomarker analysis; pharmacological study

Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesop Clinical Trial using radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Trial Evaluating The Addition Of Trastuzumab To Trimodality Treatment Of Her2-Overexpressing Esophageal Adenocarcinoma.
radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

Adenocarcinoma, Pancreas, or Neuroendocrine Tumor, Pancreas Clinical Trial using iopromide; CT

Seoul National University Hospital - Recruiting 18 years or older.
- Evaluation of Diagnostic Efficacy of Perfusion CT Using Wide Detector for Staging and Response Prediction After Chemotherapy in Pancreatic Cancer.
iopromide; CT

Sarcoma Clinical Trial using Specimen protocol

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma.
Specimen protocol

Recurrent Melanoma, or Stage IV Melanoma Clinical Trial using NA17.A2 peptide vaccine; recombinant MAGE-3.1 antigen; recombinant interleukin-12; MART-1 antigen; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase II Study of Multipeptide Vaccination With or Without IL-12, Then Combined With Regulatory T Cell Depletion Using Daclizumab in Patients With Metastatic Melanoma.
NA17.A2 peptide vaccine; recombinant MAGE-3.1 antigen; recombinant interleukin-12; MART-1 antigen; laboratory biomarker analysis

Renal Cell Carcinoma Clinical Trial using everolimus and bevacizumab

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase II Trial of Everolimus and Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma (RCC).
everolimus and bevacizumab

Colorectal Cancer Metastatic Clinical Trial using TheraSphere

BTG International Inc. - Recruiting 18 years or older.
- A Phase III Clinical Trial Evaluating TheraSpherer in Patients With Metastatic Colorectal Carcinoma of the Liver Who Have Failed First Line Chemotherapy.
TheraSphere

Carcinoma, Renal Cell Clinical Trial using Sorafenib (Nexavar, BAY43-9006)

Bayer - Recruiting 18 years or older.
- Nexavar Dose Evaluation Study in Patients With Advanced Renal Cell Carcinoma.
Sorafenib (Nexavar, BAY43-9006)

Metastatic Colorectal Cancer, Metastatic Gastric Cancer, Metastat Clinical Trial using CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract Cancers.
CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

Ovarian Cancer Clinical Trial using MK-1775; Placebo; paclitaxel; carboplatin

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- A Randomized, Phase II Study Evaluating MK-1775 in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Adult Patients With Platinum Sensitive p53 Mutant Ovarian Cancer.
MK-1775; Placebo; paclitaxel; carboplatin

Advanced Cancers Clinical Trial using Lorazepam; Placebo; Haloperidol decanoate; Questionnaires

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Preliminary Double-Blind Randomized Controlled Trial of Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer Admitted to a Palliative Care Unit.
Lorazepam; Placebo; Haloperidol decanoate; Questionnaires

Colorectal Cancer Metastatic Clinical Trial using AFLIBERCEPT AVE0005; FOLFIRI

Sanofi - Recruiting 18 years or older.
- A Multicenter, Single Arm, Open Label Clinical Trial to Evaluate the Safety and Health-Related Quality of Life of Aflibercept in Patients With Metastatic Colorectal Cancer (mCRC) Previously Treated With an Oxaliplatin-Containing Regimen.
AFLIBERCEPT AVE0005; FOLFIRI

Metastatic Breast Cancer Clinical Trial using Palbociclib; Fulvestrant; Placebo

Pfizer - Recruiting 18 years or older.
- Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Of Fulvestrant (Faslodex?) With Or Without PD-0332991 (Palbociclib) +/- Goserelin In Women With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer Whose Disease Progressed After Prior Endocrine Therapy.
Palbociclib; Fulvestrant; Placebo

Neutropenia Clinical Trial using HM10460A (45 æg/kg); HM10460A (135 æg/kg); HM10460A (270 æg/kg); Pegfilgrastim 6mg

Spectrum Pharmaceuticals, Inc - Recruiting 18 years or older.
- Phase 2, Open-Label, Dose-Ranging Study of HM10460A or Pegfilgrastim Use for the Management of Neutropenia in Patients With Breast Cancer Who Are Candidates for Adjuvant and Neoadjuvant Chemotherapy With the Docetaxel + Cyclophosphamide (TC) Regimen.
HM10460A (45 æg/kg); HM10460A (135 æg/kg); HM10460A (270 æg/kg); Pegfilgrastim 6mg

Brain and Central Nervous System Tumors, Cognitive/Functional Eff Clinical Trial using modafinil; placebo

University of South Florida - Recruiting 6 years to 17 years.
- A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor.
modafinil; placebo

Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Clinical Trial

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- The Collection and Storage of Umbilical Cord Blood for Transplantation.

Diffuse Intrinsic Pontine Glioma Clinical Trial using Bevacizumab; Erlotinib; Temozolomide; Irradiation

Dana-Farber Cancer Institute - Recruiting 3 years to 18 years.
- Phase II Trial of Molecularly Determined Treatment of Children and Young Adults With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas.
Bevacizumab; Erlotinib; Temozolomide; Irradiation

Prostate Cancer Clinical Trial using radiation therapy

Swiss Group for Clinical Cancer Research - Recruiting 18 years to 75 years.
- Dose Intensified Salvage Radiotherapy in Biochemically Relapsed Prostate Cancer Without Macroscopic Disease. A Randomized Phase III Trial..
radiation therapy

Melanoma (Skin) Clinical Trial using gene expression analysis; polymerase chain reaction; polymorphism analysis; matrix-assisted laser desorption/ionization time of flight mass spectrometry; medical chart review

Case Comprehensive Cancer Center - Recruiting N/A or older.
- Identification of Genomic Lesions Promoting Nodal Metastasis in Malignant Melanoma.
gene expression analysis; polymerase chain reaction; polymorphism analysis; matrix-assisted laser desorption/ionization time of flight mass spectrometry; medical chart review

Breast Cancer Clinical Trial using physiologic testing; screening questionnaire administration; breast imaging study; radiomammography; study of high risk factors

Case Comprehensive Cancer Center - Recruiting 50 years or older.
- Longitudinal Changes in Mammographic Density and Risk of Breast Cancer.
physiologic testing; screening questionnaire administration; breast imaging study; radiomammography; study of high risk factors

Non Small Cell Lung Cancer (NSCLC) Clinical Trial using MK-3475; Docetaxel

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- A Phase II/III Randomized Trial of Two Doses of MK-3475 (SCH900475) Versus Docetaxel in Previously Treated Subjects With Non-Small Cell Lung Cancer.
MK-3475; Docetaxel

Non- Small Cell Lung Cancer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Pilot Study of Inpatient Hospice With Procurement of Tissue on Expiration in Thoracic Malignancies.

Colorectal Cancer Clinical Trial using panitumumab; erlotinib hydrochloride; irinotecan hydrochloride

Northwestern University - Recruiting 18 years or older.
- A Randomized Phase II Study of Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Irinotecan as Second Line Therapy in Patients With Metastatic Colorectal Cancer.
panitumumab; erlotinib hydrochloride; irinotecan hydrochloride

Breast Neoplasms, Ovarian Neoplasms, Colonic Neoplasms, Prostatic Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers.

Smoking Cessation, or Smoking Clinical Trial using Smoking cessation training, support, and telephone follow-up; Smoking cessation intervention; Weekly Telephone Coaching

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Enhancing Cancer Outreach for Low-income Adults With Innovative Smoking Cessation.
Smoking cessation training, support, and telephone follow-up; Smoking cessation intervention; Weekly Telephone Coaching

Breast Cancer Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Clinical Significance of Germline BRCA Mutations.

Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Clinical Trial using bortezomib; mitoxantrone hydrochloride; etoposide; cytarabine; flow cytometry

Case Comprehensive Cancer Center - Recruiting 18 years to 70 years.
- A Phase I Study of Bortezomib in Combination With MEC (Mitoxantrone, Etoposide, and Intermediate-Dose Cytarabine) for Relapsed/ Refractory Acute Myelogenous Leukemia (AML).
bortezomib; mitoxantrone hydrochloride; etoposide; cytarabine; flow cytometry

Oral Cancer Clinical Trial using Fluorescence Spectroscopy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Fluorescence and Reflectance Spectroscopy for Diagnostic Assessment of Oral Mucosal Lesions.
Fluorescence Spectroscopy

Bladder Cancer Clinical Trial using cisplatin; fluorouracil; mitomycin C

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- A Phase II Protocol for Patients With Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent With Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging.
cisplatin; fluorouracil; mitomycin C

Breast Cancer Clinical Trial using gene expression analysis; immunohistochemistry staining method; laboratory biomarker analysis

Case Comprehensive Cancer Center - Recruiting N/A or older.
- Assessment of Candidate Protein Expression in Human Breast Cancer Specimens.
gene expression analysis; immunohistochemistry staining method; laboratory biomarker analysis

Tissue Analysis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 19 years or older.
- Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI).

Glioblastoma Multiforme, Squamous Cell Carcinoma of Head and Neck Clinical Trial using CC-115

Celgene Corporation - Recruiting 18 years or older.
- A Phase 1a/b, Multicenter, Open Label, Dose-Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Dual DNA-PK and TOR Kinase Inhibitor, CC-115, Administered Orally to Subjects With Advanced Solid Tumors, and Hematologic Malignancies..
CC-115

Rectal Cancer Clinical Trial using nitroglycerin

University of Texas Southwestern Medical Center - Recruiting 18 years to 90 years.
- Phase I Dose Escalation Trial of Nitroglycerin in Addition to 5-flourouracil and Radiation Therapy for Neo-adjuvant Treatment of Operable Rectal Cancer.
nitroglycerin

Average-risk Patients for Colon Cancer Clinical Trial using Stool DNA Test; biopsies of rectal and colon mucosa; Questionnaires

Case Comprehensive Cancer Center - Recruiting 30 years to 80 years.
- Screening and Risk Factors of Colon Neoplasia.
Stool DNA Test; biopsies of rectal and colon mucosa; Questionnaires

Prostate Cancer Clinical Trial using bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; orteronel; triptorelin

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) With a GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT With a GNRH Agonist and TAK-700 For Men With High Risk Prostate Cancer.
bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; orteronel; triptorelin

Quality of Life Clinical Trial using quality of life

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Brody Belt - Alternative Method of Securing a Patient's Urinary Drainage Bag.
quality of life

Pancreatic Cancer Clinical Trial using Gemcitabine; Radiation therapy; pancreaticoduodenectomy

University of Arkansas - Recruiting 18 years or older.
- A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemotherapy With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas.
Gemcitabine; Radiation therapy; pancreaticoduodenectomy

Gallbaldder Cancer, or Gallstones Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Pilot Study of Gallbladder Cancer in Chile.

Non Treated Cancer of Upper Aero Digestive Tract Clinical Trial using interview; questionnaires

Centre Oscar Lambret - Recruiting 18 years or older.
- Determinants of the Consultation Delay in Cancers of the Upper Aero Digestive Tract.
interview; questionnaires

Metastatic Melanoma, or Skin Cancer Clinical Trial using Cyclophosphamide; Fludarabine; Young TIL

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- A Pilot Study of the Administration of Young Tumor Infiltrating Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen in Metastatic Melanoma.
Cyclophosphamide; Fludarabine; Young TIL

Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms, O Clinical Trial using GyneGals Support Group

Women's College Hospital - Recruiting 18 years or older.
- A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer.
GyneGals Support Group

Pediatric Cancer Clinical Trial using Education; Cotinine Education

University of South Florida - Recruiting 2 years to 12 years.
- Cotinine Feedback as an Intervention to Change Parental/Caregiver Smoking Behavior Around Children With Cancer.
Education; Cotinine Education

Women at Increased Risk for Developing Breast Carcinoma Clinical Trial using Mammography (CESM) and MRI

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- Comparison of Contrast Enhanced Mammography to Breast MRI in Screening Patients at Increased Risk for Breast Cancer.
Mammography (CESM) and MRI

Prostate Cancer Clinical Trial using Best Systemic Therapy (BST); Best Systemic Therapy (BST) + Surgery or Radiation Therapy; Questionnaires; Phone Call/Email

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Randomized, Phase II Trial of Best Systemic Therapy or Best Systemic Therapy (BST) Plus Definitive Treatment (Radiation or Surgery) of the Primary Tumor in Metastatic (M1) Prostate Cancer (PC).
Best Systemic Therapy (BST); Best Systemic Therapy (BST) + Surgery or Radiation Therapy; Questionnaires; Phone Call/Email

Cancer Clinical Trial using Questionnaires

Centre Oscar Lambret - Recruiting 18 years to 55 years.
- Cancer of the Upper Aero-digestive Tract and Future Socioprofessional.
Questionnaires

Cancer of the Pancreas Clinical Trial using Pioglitazone

University of Texas Southwestern Medical Center - Recruiting 18 years or older.
- A Phase II Study of Pioglitazone for Patients With Cancer of the Pancreas.
Pioglitazone

Chronic Pulmonary Disorder Clinical Trial using breathing techniques; Self-Administered Baseline and Transition Dyspnea Indexes

Memorial Sloan-Kettering Cancer Center - Recruiting 19 years or older.
- Breath Training Exercise for the Reduction of Chronic Dyspnea: a Pilot Study.
breathing techniques; Self-Administered Baseline and Transition Dyspnea Indexes

Prostatic Neoplasms Clinical Trial using VT-122; Placebo

Vicus Therapeutics - Recruiting 18 years or older.
- A Randomized, Placebo Controlled, Multicenter Phase 2 Study of Etodolac and Propranolol in Patients With Clinically Progressive Prostate Cancer.
VT-122; Placebo

Recurrent Melanoma, Stage IA Melanoma, Stage IB Melanoma, Stage I Clinical Trial using fluorescein sodium injection; diagnostic microscopy; therapeutic conventional surgery; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Pilot Study of Feasibility of Performing Intravital Microscopy in Melanoma Patients.
fluorescein sodium injection; diagnostic microscopy; therapeutic conventional surgery; laboratory biomarker analysis

Prostate Cancer, Erectile Dysfunction Following Radical Prostatec Clinical Trial using Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Case Comprehensive Cancer Center - Recruiting 21 years or older.
- Improving Erectile Function and Quality of Life After Prostate Cancer Treatment.
Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Stage IA Endometrial Carcinoma, Stage IB Endometrial Carcinoma, S Clinical Trial using lymph node mapping; sentinel lymph node biopsy; isosulfan blue; indocyanine green solution; therapeutic conventional surgery; lymphadenectomy

Case Comprehensive Cancer Center - Recruiting N/A or older.
- Sentinel Lymph Node Mapping for Endometrial Cancer.
lymph node mapping; sentinel lymph node biopsy; isosulfan blue; indocyanine green solution; therapeutic conventional surgery; lymphadenectomy

Ovarian Cancer Clinical Trial using IMAB027

Ganymed Pharmaceuticals AG - Recruiting 18 years or older.
- A First-in-human Dose Escalation and Dose Finding Phase 1/2 Trial of IMAB027 in Patients With Recurrent Advanced Ovarian Cancer (OVAR).
IMAB027

Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, or Clinical Trial

Lund University - Recruiting 35 years to 80 years.
- Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) and Cardiovascular Diseases in Smokers/Ex-Smokers Attending Primary Care - Longitudinal Study.

Breast Cancer Clinical Trial using Aerobic Activity; Dietician Counseling; Yoga; Cognitive Behavior Therapy; Smoking Cessation Counseling; Questionnaires; Saliva Samples; Dietary Assessment; Blood Samples

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- The Role of Lifestyle Factors in Breast Cancer-Related Outcomes.
Aerobic Activity; Dietician Counseling; Yoga; Cognitive Behavior Therapy; Smoking Cessation Counseling; Questionnaires; Saliva Samples; Dietary Assessment; Blood Samples

Hematopoietic/Lymphoid Cancer, Non-hodgkin Lymphoma,B Cell, or Re Clinical Trial using Biological: anti-CD19-CAR vector-transduced T cells genetically engineered lymphocyte therapy

Chinese PLA General Hospital - Recruiting 50 years to 80 years.
- Anti-CD19 Chimeric Antigen Receptor Modified T Cells Infusion in Mantle Cell Lymphoma.
Biological: anti-CD19-CAR vector-transduced T cells genetically engineered lymphocyte therapy

Breast Cancer Clinical Trial using Nutrition Education; Acupuncture

Mount Sinai School of Medicine - Recruiting 18 years or older.
- Comparison of Weight Loss Among Early Stage Breast Cancer Patients Post Chemotherapy: Nutrition Education in Combination With Weight Loss Acupuncture Vs. Nutrition Education Alone.
Nutrition Education; Acupuncture

Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Diffuse Large Clinical Trial using GS-9973

Gilead Sciences - Recruiting 18 years or older.
- A Phase 2, Open-Label Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacodynamics of GS-9973 in Subjects With Relapsed or Refractory Hematologic Malignancies.
GS-9973

Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, G Clinical Trial using Rindopepimut (CDX-110) with GM-CSF; Temozolomide; KLH

Celldex Therapeutics - Recruiting 18 years or older.
- An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF With Adjuvant Temozolomide in Patients With Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma.
Rindopepimut (CDX-110) with GM-CSF; Temozolomide; KLH

Hematological Malignancies, Certain Lysosomal Storage and Peroxis Clinical Trial using A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)

Center for International Blood and Marrow Transplant Research - Recruiting N/A or older.
- A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications.
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)

Glioblastoma Clinical Trial using Selinexor

Karyopharm Therapeutics, Inc - Recruiting 18 years or older.
- A Phase II, Two-tier Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Patients With Recurrent Glioblastoma After Failure of Radiation Therapy and Temozolomide.
Selinexor

Stage IB Breast Cancer, or Stage II Breast Cancer Clinical Trial using regional nodal XRT; chestwall XRT; WBI

National Surgical Adjuvant Breast and Bowel Project (NSABP) - Recruiting 18 years or older.
- A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy.
regional nodal XRT; chestwall XRT; WBI

Carcinoma, Non-Small-Cell Lung Clinical Trial using afatinib

Boehringer Ingelheim - Recruiting 18 years or older.
- An Open Label Trial of Afatinib (Giotrif) in Treatment-naive (1st Line) or Chemotherapy Pre-treated Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s).
afatinib

Head and Neck Neoplasms Clinical Trial using methotrexate; afatinib

Boehringer Ingelheim - Recruiting 18 years or older.
- A Randomised, Open-label, Phase III Study to Evaluate the Efficacy and Safety of Oral Afatinib (BIBW 2992) Versus Intravenous Methotrexate in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma Who Have Progressed After Platinum-based Therapy.
methotrexate; afatinib

Neoplasms Clinical Trial using BI 853520

Boehringer Ingelheim - Recruiting 18 years or older.
- An Open Label Phase I Dose Finding Study of BI 853520 Administered Orally in a Continuous Dosing Schedule in Patients With Various Advanced or Metastatic Non-hematologic Malignancies.
BI 853520

Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bon Clinical Trial using Denosumab; Zoledronic acid

Amgen - Recruiting 18 years or older.
- A Randomized, Double-Blind, Multicenter Study of Denosumab Compared With Zoledronic Acid (Zometar) in the Treatment of Bone Disease in Subjects With Newly Diagnosed Multiple Myeloma.
Denosumab; Zoledronic acid

Head and Neck Neoplasms Clinical Trial using Placebo; Afatinib

Boehringer Ingelheim - Recruiting 18 years or older.
- A Randomised, Double-blind, Placebo-controlled, Phase III Study to Evaluate the Efficacy and Safety of Afatinib (BIBW 2992) as Adjuvant Therapy After Chemo-radiotherapy in Primary Unresected Patients With Stage III, IVa, or IVb Loco-regionally Advanced Head and Neck Squamous Cell Carcinoma.
Placebo; Afatinib

Carcinoma, Non-Small-Cell Lung Clinical Trial using Afatinib

Boehringer Ingelheim - Recruiting 18 years or older.
- An Open Label, Multicentre, Single Arm Trial to Assess the Safety of Afatinib for Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s).
Afatinib

Non-Small Cell Lung Cancer Clinical Trial using Denosumab; Zometa

Amgen - Recruiting 18 years or older.
- A Randomized, Double-blind, Multi-center Phase 2 Trial of Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer.
Denosumab; Zometa

Non-small Cell Lung Cancer Clinical Trial using MK-3475

Merck Sharp & Dohme Corp. - Recruiting 20 years or older.
- An Open-label, Non-randomized, Multi-center Phase Ib Study of MK-3475 in Subjects With PD-L1 Positive Advanced Non-Small Cell Lung Cancer.
MK-3475

Childhood Mixed Glioma, Untreated Childhood Anaplastic Astrocytom Clinical Trial using veliparib; temozolomide; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting N/A to 21 years.
- A Phase I/II Study of ABT-888, an Oral Poly(ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children With Newly Diagnosed Diffuse Pontine Gliomas (DIPG).
veliparib; temozolomide; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy; pharmacological study; laboratory biomarker analysis

Carcinoma, Non-Small-Cell Lung Clinical Trial using Dose escalation followed by treatment with MTD

Boehringer Ingelheim - Recruiting 18 years or older.
- A Phase 1b Study of Intermittent Administration of High Doses of the Irreversible EGFR Inhibitor Afatinib as a Means of Achieving Plasma Levels Active Against Non-small Cell Lung Cancer With Known T790M Mutations.
Dose escalation followed by treatment with MTD

Breast Neoplasms, or Stomach Neoplasms Clinical Trial using Herceptin; afatinib; trastuzumab

Boehringer Ingelheim - Recruiting 18 years or older.
- Phase I Trial of Afatinib in Combination With 3 Weekly Trastuzumab in Patients With Tumours Overexpressing HER2. Once the MTD of Afatinib With 3 Weekly Trastuzumab Was Established the Safety of This Dose Will be Assessed Also in Combination With Weekly Trastuzumab..
Herceptin; afatinib; trastuzumab

Neoplasms Clinical Trial using BI 853520

Boehringer Ingelheim - Recruiting 20 years or older.
- An Open-label Phase I Dose Finding Study of BI 853520 Administered Orally in a Continuous Dosing Schedule in Japanese and Taiwanese Patients With Various Advanced or Metastatic Solid Tumours.
BI 853520

Advanced Cancer Clinical Trial using Dasatinib; Bevacizumab; Paclitaxel

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Phase I Trial of Dasatinib (Src Inhibitor), Bevacizumab (Anti-VEGF Monoclonal Antibody) and Metronomic Paclitaxel in Patients With Advanced Malignancies.
Dasatinib; Bevacizumab; Paclitaxel

Prostate Cancer, Castration Resistant Prostate Cancer, Pain, or P Clinical Trial using cabozantinib; mitoxantrone; prednisone

Exelixis - Recruiting 18 years or older.
- A Phase 3, Randomized, Double-blind, Controlled Trial of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer.
cabozantinib; mitoxantrone; prednisone

Non-Small Cell Lung Cancer, Anemia, Cancer, or Lung Cancer Clinical Trial using darbepoetin alfa 500 mcg Q3W; placebo

Amgen - Recruiting 18 years or older.
- A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long-term Safety and Efficacy of Darbepoetin Alfa Administered at 500 µg Once-Every-3-Weeks in Anemic Subjects With Advanced Stage Non-small Cell Lung Cancer Receiving Multi-cycle Chemotherapy.
darbepoetin alfa 500 mcg Q3W; placebo

Neoplasms Clinical Trial using BI 836845

Boehringer Ingelheim - Recruiting 18 years or older.
- A Phase I Dose Escalation Trial of Weekly Intravenous Administrations of BI 836845 in Patients With Advanced Solid Cancers With Repeated Administrations in Patients Showing Clinical Benefit.
BI 836845

Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Clinical Trial using veliparib; cyclophosphamide; doxorubicin hydrochloride; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Study of ABT-888 in Combination With Cyclophosphamide in Solid Tumors or Non-Hodgkins Lymphoma.
veliparib; cyclophosphamide; doxorubicin hydrochloride; laboratory biomarker analysis; pharmacological study

Vaginal Cancer Clinical Trial using Magnetic Resonance Imaging (MRI); Diffusion Weighted Magnetic Resonance Imaging (DWMR)

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Magnetic Resonance Imaging of Gynecologic Malignancies Involving the Vagina.
Magnetic Resonance Imaging (MRI); Diffusion Weighted Magnetic Resonance Imaging (DWMR)

Cancer, Solid Tumor Clinical Trial using MK-3475 1 mg/kg; MK-3475 3 mg/kg; MK-3475 10 mg/kg; MK-3475 MEL; MK-3475 NSCLC; MK-3475 MEL Low Dose; MK-3475 MEL High Dose; MK-3475 NSCLC Low Dose; MK-3475 NSCLC High Dose; MK-3475 NSCLC Medium Dose

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- Phase I Study of Single Agent MK-3475 in Patients With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, and Non-Small Cell Lung Carcinoma.
MK-3475 1 mg/kg; MK-3475 3 mg/kg; MK-3475 10 mg/kg; MK-3475 MEL; MK-3475 NSCLC; MK-3475 MEL Low Dose; MK-3475 MEL High Dose; MK-3475 NSCLC Low Dose; MK-3475 NSCLC High Dose; MK-3475 NSCLC Medium Dose

Liver Cancer Clinical Trial using yttrium Y 90 glass microspheres; Cisplatin; Mitomycin; Doxorubicin

Northwestern University - Recruiting 18 years or older.
- An Investigator Initiated Multicenter Prospective Randomized Study of Chemoembolization Versus Radioembolization for the Treatment of Hepatocellular Carcinoma (PREMIERE Trial).
yttrium Y 90 glass microspheres; Cisplatin; Mitomycin; Doxorubicin

Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adeno Clinical Trial using veliparib; pegylated liposomal doxorubicin hydrochloride; carboplatin; bevacizumab; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Pegylated Liposomal Doxorubicin (PLD), Carboplatin, and NCI Supplied Veliparib (ABT-888), and NCI Supplied Bevacizumab in Recurrent Platinum Sensitive Ovarian, Primary Peritoneal and Fallopian Tube Cancer.
veliparib; pegylated liposomal doxorubicin hydrochloride; carboplatin; bevacizumab; laboratory biomarker analysis

Recurrent Non-small Cell Lung Cancer, or Stage IV Non-small Cell Clinical Trial using cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Trial of XL184 (Cabozantinib) Plus Erlotinib in Patients With Advanced EGFR-Mutant Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Therapy.
cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

Metastatic Breast Cancer Clinical Trial using Paclitaxel; Bevacizumab; Letrozole; Anastrozole; Exemestane; Fulvestrant; Goserelin; leuprorelin acetate

Japan Breast Cancer Research Group - Recruiting 20 years to 75 years.
- Bevacizumab Plus Paclitaxel Optimization Study With Interventional Maintenance Endocrine Therapy in Advanced or Metastatic ER-positive HER2-negative Breast Cancer -BOOSTER Trial, a Multicenter Randomized Phase II Study-.
Paclitaxel; Bevacizumab; Letrozole; Anastrozole; Exemestane; Fulvestrant; Goserelin; leuprorelin acetate

Brain Cancer Clinical Trial using Vorinostat; Bevacizumab

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma.
Vorinostat; Bevacizumab

Leukemia, or Lymphoma Clinical Trial using Rasburicase; Allopurinol

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Randomized Phase 2 Study to Evaluate the Efficacy of Rasburicase in Patients at Risk for TLS During Two Cycles of Chemotherapy.
Rasburicase; Allopurinol

B-cell Childhood Acute Lymphoblastic Leukemia, Peripheral T-cell Clinical Trial using dexamethasone; mitoxantrone hydrochloride; temsirolimus; vincristine sulfate; pegaspargase; methotrexate; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 1 year to 21 years.
- A Phase 1 Study of Temsirolimus in Combination With Intensive Re-Induction Therapy for Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma.
dexamethasone; mitoxantrone hydrochloride; temsirolimus; vincristine sulfate; pegaspargase; methotrexate; laboratory biomarker analysis; pharmacological study

Skin Cancer Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting 10 years or older.
- In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin.

Glioblastoma, or Recurrent Metastatic Cancer to the Brain Clinical Trial using ExAblate 4000

InSightec - Recruiting 18 years to 70 years.
- A Feasibility Study to Evaluate the Safety and Feasibility of Transcranial MRI-Guided Focused Ultrasound Surgery in the Treatment of Brain Lesions.
ExAblate 4000

Carcinoma, or Lymphoma Clinical Trial using rh IL-15

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase I Study of a Continuous Intravenous Infusion of Recombinant Human Interleukin IL-15 (rhIL-15) in Adults With Metastatic Cancers.
rh IL-15

Mixed Muellerian Cancer, Cervical Cancer, Ovarian Cancer, Breast Clinical Trial using Carboplatin; Olaparib; Treatment Effect

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Pharmacokinetic/Pharmacodynamic Study With a Phase I Run-In With a PARP Inhibitor (Olaparib) in Combination With Carboplatin for Refractory or Recurrent Women's Cancers.
Carboplatin; Olaparib; Treatment Effect

Cancer, or Solid Tumor Clinical Trial using MK-3475

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- A Phase Ib Multi-Cohort Study of MK-3475 in Subjects With Advanced Solid Tumors.
MK-3475

HER2 Positive Metastatic Breast Cancers Clinical Trial using ONT-380; Capecitabine; Trastuzumab

Oncothyreon Inc. - Recruiting 18 years or older.
- A Phase 1b, Open-label Study to Assess the Safety and Tolerability of ONT-380 Combined With Capecitabine and Trastuzumab, Alone and in Combination in HER2+ Metastatic Breast Cancer.
ONT-380; Capecitabine; Trastuzumab

Hepatic Complications, Liver Metastases, or Unspecified Adult Sol Clinical Trial using trametinib; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Single Agent Trametinib (GSK1120212) in Advanced Cancer Patients With Hepatic Dysfunction.
trametinib; pharmacological study; laboratory biomarker analysis

Melanoma Clinical Trial using Dabrafenib

Memorial Sloan-Kettering Cancer Center - Recruiting 16 years or older.
- A Phase 2 Trial of Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation.
Dabrafenib

Breast Cancer Clinical Trial using Verbal and Written Instruction; Verbal and Written Plus Simulation

Memorial Sloan-Kettering Cancer Center - Recruiting 19 years or older.
- A Comparison of Strategies for Injection Teaching: Verbal and Written Instruction Versus Verbal and Written Plus Simulation in Patients With Breast Cancer and Their Caregivers.
Verbal and Written Instruction; Verbal and Written Plus Simulation

Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer Clinical Trial using exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE).
exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

Prostate Cancer, or Metastatic (Spread to Other Areas of the Body Clinical Trial using BKM120

Duke University - Recruiting 18 years or older.
- Phase II Study of BKM120 in Men With Metastatic Castration-Resistant Prostate Cancer.
BKM120

Breast Cancer, Lobular Carcinoma, or Invasive Breast Cancer Clinical Trial using Tissue specimen

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ.
Tissue specimen

Recurrent Childhood Medulloblastoma, Recurrent Childhood Pineobla Clinical Trial using temozolomide; irinotecan hydrochloride; bevacizumab

National Cancer Institute (NCI) - Recruiting N/A to 21 years.
- Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, a COG Randomized Phase II Screening Trial.
temozolomide; irinotecan hydrochloride; bevacizumab

Transplantation Infection Clinical Trial using Cidofovir; No Cidofovir

M.D. Anderson Cancer Center - Recruiting 6 years or older.
- A Phase II Randomized Study of Cidofovir Versus Best Supportive Care for Polyomavirus Hominis Type I (BK) Virus Related Hemorrhagic Cystitis After Stem Cell Transplant.
Cidofovir; No Cidofovir

Prostate Cancer Clinical Trial using tasquinimod; tasquinimod 0.25 mg; 0.5 mg; tasquinimod 0.25 mg; 0.5 mg; 1.0 mg

Duke University - Recruiting 18 years to 79 years.
- The CATCH Prostate Cancer Trial: Cabazitaxel And Tasquinimod in Men With Castration-Resistant Heavily Pre-treated Prostate Cancer.
tasquinimod; tasquinimod 0.25 mg; 0.5 mg; tasquinimod 0.25 mg; 0.5 mg; 1.0 mg

Recurrent Small Cell Lung Cancer Clinical Trial using veliparib; temozolomide; placebo; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Multi-center, Randomized, Double-Blind Phase II Study Comparing ABT-888, a PARP Inhibitor, Versus Placebo With Temozolomide in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer.
veliparib; temozolomide; placebo; laboratory biomarker analysis

Glioma, or Metastatic Brain Cancer Clinical Trial using ExAblate Transcranial System

InSightec - Recruiting 18 years to 75 years.
- A Study to Evaluate the Safety and Feasibility of Transcranial MRI-Guided Focused Ultrasound Surgery in the Treatment of Brain Tumors.
ExAblate Transcranial System

Disorder Related to Bone Marrow Transplantation, Leukemia, or Tra Clinical Trial using Fludarabine; Clofarabine; Busulfan; Thymoglobulin; Stem Cell Infusion; Tacrolimus; Methotrexate

M.D. Anderson Cancer Center - Recruiting 3 years to 70 years.
- A Randomized Study of Once Daily Fludarabine-Clofarabine Versus Fludarabine Alone Combined With Intervenous Busulfan Followed by Allogeneic Hemopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS).
Fludarabine; Clofarabine; Busulfan; Thymoglobulin; Stem Cell Infusion; Tacrolimus; Methotrexate

Insular Thyroid Cancer, Recurrent Thyroid Cancer, Stage I Follicu Clinical Trial using cabozantinib-s-malate; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Study of Cabozantinib in Patients With Radioiodine-Refractory Differentiated Thyroid Cancer Who Progressed on First-Line VEGFR-Targeted Therapy.
cabozantinib-s-malate; laboratory biomarker analysis

Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Clinical Trial using tivantinib; cetuximab; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase II Trial of ARQ 197 (Tivantinib) /Cetuximab Versus Cetuximab in Patients With Recurrent/Metastatic Head and Neck Cancer.
tivantinib; cetuximab; laboratory biomarker analysis

HIV Infection, or Unspecified Adult Solid Tumor, Protocol Specifi Clinical Trial using cabozantinib-s-malate; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase I Trial of Cabozantinib (XL184) for Advanced Solid Tumors in Persons With HIV Infection.
cabozantinib-s-malate; pharmacological study; laboratory biomarker analysis

Recurrent Thyroid Cancer Clinical Trial using lapatinib ditosylate; dabrafenib; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Dabrafenib in Combination With Lapatinib in BRAF Mutant Thyroid Cancer.
lapatinib ditosylate; dabrafenib; pharmacological study; laboratory biomarker analysis

Untreated Childhood Anaplastic Astrocytoma, Untreated Childhood A Clinical Trial using WEE1 inhibitor MK-1775; radiation therapy; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 37 Months to 21 years.
- A Phase 1 Study of MK-1775 Concurrent With Local Radiation Therapy for the Treatment of Newly Diagnosed Children With Diffuse Intrinsic Pontine Gliomas.
WEE1 inhibitor MK-1775; radiation therapy; pharmacological study; laboratory biomarker analysis

Recurrent Melanoma, Stage IIIA Melanoma, Stage IIIB Melanoma, Sta Clinical Trial using dabrafenib; ipilimumab; trametinib; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Sequential Safety and Biomarker Study of BRAF-MEK Inhibition on the Immune Response in the Context of CTLA-4 Blockade for BRAF Mutant Melanoma.
dabrafenib; ipilimumab; trametinib; laboratory biomarker analysis

Recurrent Neuroblastoma Clinical Trial using temozolomide; irinotecan hydrochloride; temsirolimus; monoclonal antibody Ch14.18; sargramostim; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting N/A or older.
- A Phase II Randomized Trial of Irinotecan/Temozolomide With Temsirolimus (NSC# 683864) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408) in Children With Refractory, Relapsed or Progressive Neuroblastoma.
temozolomide; irinotecan hydrochloride; temsirolimus; monoclonal antibody Ch14.18; sargramostim; laboratory biomarker analysis

Patients Seen at a Urology Consultation Clinical Trial using Questionnaire

Centre Hospitalier Universitaire Dijon - Recruiting 50 years to 70 years.
- STUDY OF PREFERENCES IN MEN FACED WITH THE DIFFERENT TREATMENT OPTIONS FOR LOCALIZED PROSTRATE CANCER WITH A GOOD OR INTERMEDIATE PROGNOSIS.
Questionnaire

Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer, or Clinical Trial using cabozantinib-s-malate; sunitinib malate; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Randomized Phase II Study Comparing Cabozantinib With Commercially Supplied Sunitinib in Patients With Previously Untreated Locally Advanced or Metastatic Renal Cell Carcinoma.
cabozantinib-s-malate; sunitinib malate; laboratory biomarker analysis

Myeloma Clinical Trial using Pomalidomide; Dexamethasone; G-CSF; Phone Calls

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Phase I/II Study of Pomalidomide and Dexamethasone With Growth Factor Support in Patients With Relapsed/Refractory Multiple Myeloma.
Pomalidomide; Dexamethasone; G-CSF; Phone Calls

Multiple Myeloma Clinical Trial using lenalidomide; pidilizumab; pharmacological study; laboratory biomarker analysis

Ohio State University Comprehensive Cancer Center - Recruiting 18 years or older.
- Phase I/II Study of Lenalidomide in Combination With Anti-PD-1 Monoclonal Antibody CT-011 in Patients With Relapsed/Refractory Multiple Myeloma.
lenalidomide; pidilizumab; pharmacological study; laboratory biomarker analysis

Joint Pain, or Breast Cancer Clinical Trial using Walk with Ease

University of North Carolina, Chapel Hill - Recruiting 21 years or older.
- Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy.
Walk with Ease

Myeloma Clinical Trial using Thalidomide; Lenalidomide; Questionnaires

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Pilot Study of Thalidomide to Overcome Lenalidomide Resistance in Patients Suffering Biochemical Progression on Maintenance Therapy After Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma.
Thalidomide; Lenalidomide; Questionnaires

Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Ca Clinical Trial using fulvestrant; anastrozole

Alliance for Clinical Trials in Oncology - Recruiting 18 years or older.
- Alternate Approaches for Clinical Stage II or III Estrogen Receptor Positive Breast Cancer Neoadjuvant Treatment (ALTERNATE) in Postmenopausal Women: A Phase III Study.
fulvestrant; anastrozole

Rectal Cancer Clinical Trial

Uppsala University - Recruiting 18 years or older.
- IPC Status as a Surgical Quality Marker in Rectal Cancer Surgery.

Adenocarcinoma of Head of Pancreas, Cholangio Carcinoma, Duodenal Clinical Trial using Open surgery; Laparoscopic surgery

GEM Hospital & Research Center - Recruiting 30 years to 70 years.
- A Prospective Randomized Parallel Group Trial : Laparoscopic Versus Open Pancreatoduodenectomy in Terms of Pathological Radicality & Severity Short Term of Complications According to Expanded Accordion Severity Grading System.
Open surgery; Laparoscopic surgery

Carcinoma, Hepatocellular Clinical Trial using Everolimus; Tacrolimus; Myfortic; CellCept

Baylor Research Institute - Recruiting 18 years or older.
- A 36 Month Multi-center, Open Label, Randomized, Comparator Study to Evaluate the Efficacy and Safety of Everolimus Immunosuppression Treatment in Liver Transplantation for Hepatocellular Carcinoma Exceeding Milan Criteria.
Everolimus; Tacrolimus; Myfortic; CellCept

Malignant Neoplasm Clinical Trial using computer-assisted intervention; Standard educational information

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- Tailoring Patient Education to Perceived Risk for Falls in Hospitalized Oncology Patients: A Pilot Study.
computer-assisted intervention; Standard educational information

Colorectal Carcinoma Clinical Trial using BBI608; Placebo; Best Supportive Care

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Phase III Randomized Study of BBI608 and Best Supportive Care Versus Placebo and Best Supportive Care in Patients With Pretreated Advanced Colorectal Carcinoma.
BBI608; Placebo; Best Supportive Care

Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, G Clinical Trial using Bevacizumab; Rindopepimut (CDX-110) with GM-CSF; KLH

Celldex Therapeutics - Recruiting 18 years or older.
- A Phase II Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma.
Bevacizumab; Rindopepimut (CDX-110) with GM-CSF; KLH

Advanced Soft Tissue Sarcoma Clinical Trial using TRC105 and Pazopanib

Tracon Pharmaceuticals Inc. - Recruiting 18 years or older.
- A Phase 1B Dose-escalation Study of TRC105 in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma.
TRC105 and Pazopanib

Myeloproliferative Neoplasms Clinical Trial using Ruxolitinib; Decitabine

Mount Sinai School of Medicine - Recruiting 18 years or older.
- Multicenter Phase I/II Trial of Ruxolitinib in Combination With Decitabine in Patients With Accelerated Phase Myeloproliferative Neoplasm (MPN) or Post-MPN AML.
Ruxolitinib; Decitabine

Solid Tumors Clinical Trial using thioureidobutyronitrile

Cellceutix Pharmaceuticals - Recruiting 18 years or older.
- A Phase 1, Open-Label, Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of Kevetrin (Thioureidobutyronitrile) Administered Intravenously, in Patients With Advanced Solid Tumors.
thioureidobutyronitrile

Indolent Non-Hodgkin's Lymphoma, Follicular Lymphoma, Small Lymph Clinical Trial using Idelalisib

Gilead Sciences - Recruiting 18 years or older.
- Single-agent CAL-101 for Previously Teated Low-grade Lymphoma: A Phase 1/2 Study of Safety, Efficacy, and Flow-cytometric Assessment of Tumor-cell Signaling Events.
Idelalisib

To Improve the Informed Consent Process Clinical Trial using Consent Form Specific Format 1 or 2

Medical College of Wisconsin - Recruiting 18 years or older.
- Easy-to-Read Informed Consent (ETRIC) for Hematopoietic Cell Transplantation Clinical Trials (BMT CTN 1205).
Consent Form Specific Format 1 or 2

Solid Cancers Clinical Trial using letrozole; fulvestrant; GDC-0032

Genentech - Recruiting 18 years or older.
- An Open-Label, Phase I/II, Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Patients With Locally Advanced or Metastatic Solid Tumors and in Combination With Endocrine Therapy in Patients With Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer.
letrozole; fulvestrant; GDC-0032

Colorectal Cancer Clinical Trial using bevacizumab; FOLFIRI regimen; mFOLFOX6

Genentech - Recruiting 18 years or older.
- A Randomized Phase II Study of Bevacizumab/mFOLFOX6 Versus Bevacizumab/Folfiri With Biomarker Stratification in Patients With Previously Untreated Metastatic Colorectal Cancer.
bevacizumab; FOLFIRI regimen; mFOLFOX6

Ovarian Cancer Clinical Trial

Genentech - Recruiting 18 years or older.
- Patient Reported Symptoms in Ovarian Cancer.

Non-Small Cell Lung Cancer Clinical Trial using onartuzumab [MetMAb]; erlotinib [Tarceva]; Placebo

Genentech - Recruiting 18 years or older.
- A Randomized, Phase III, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Onartuzumab (Metmab) in Combination With Tarceva (Erlotinib) in Patients With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Standard Chemotherapy for Advanced/Metastatic Disease.
onartuzumab [MetMAb]; erlotinib [Tarceva]; Placebo

Prostatic Neoplasms Clinical Trial using BAY2010112

Bayer - Recruiting 18 years or older.
- An Open-label, Phase I, Dose-escalation Study to Characterize the Safety, Tolerability, Pharmacokinetics, and Maximum Tolerated Dose of BAY2010112 Given Once Daily by Subcutaneous Administration in Subjects With Castration-resistant Prostate Cancer.
BAY2010112

Endometrial Cancer Clinical Trial using AEZS-108 / zoptarelin doxorubicin; doxorubicin

AEterna Zentaris - Recruiting 18 years or older.
- Randomized Controlled Study Comparing AEZS-108 With Doxorubicin as Second Line Therapy for Locally Advanced, Recurrent or Metastatic Endometrial Cancer..
AEZS-108 / zoptarelin doxorubicin; doxorubicin

Breast Cancer Clinical Trial using GDC-0941; placebo; fulvestrant; GDC-0980

Genentech - Recruiting 18 years or older.
- A Phase II, Double-Blind, Placebo Controlled, Randomized Study of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in Patients Resistant to Aromatase Inhibitor Therapy.
GDC-0941; placebo; fulvestrant; GDC-0980

Breast Cancer Clinical Trial using GDC-0941; Placebo; paclitaxel

Genentech - Recruiting 18 years or older.
- A Phase II, Randomized Study of Paclitaxel With GDC-0941 Versus Paclitaxel With Placebo in Patients With Locally Recurrent or Metastatic Breast Cancer.
GDC-0941; Placebo; paclitaxel

Non-Small Cell Lung Cancer Clinical Trial using MPDL3280A

Genentech - Recruiting 18 years or older.
- A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients With PD-L1-Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer.
MPDL3280A

Non-Small Cell Lung Cancer, Ovarian Cancer Clinical Trial using DNIB0600A

Genentech - Recruiting 18 years or older.
- A Phase I, Open-Label Study of the Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Patients With Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer.
DNIB0600A

Ovarian Cancer, Pancreatic Cancer Clinical Trial using DMUC5754A

Genentech - Recruiting 18 years or older.
- A Phase I, Open-Label, Dose Escalation Study of the Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer.
DMUC5754A

Breast Cancer Clinical Trial

Genentech - Recruiting 18 years or older.
- An Observational Cohort Study Of Treatment Patterns And Outcomes In Patients With HER2 Positive (Her2+) Metastatic Breast Cancer (SystHERs Registry (Systematic Therapies for HER2+ Metastatic Breast Cancer Study))..

Head and Neck Cancer Clinical Trial using MEHD7945A; cisplatin; 5-FU; carboplatin; paclitaxel

Genentech - Recruiting 18 years or older.
- A Phase 1b Open-Label Study of the Safety and Pharmacokinetics of MEHD7945A in Combination With Either Cisplatin and 5-FU or Paclitaxel and Carboplatin in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck.
MEHD7945A; cisplatin; 5-FU; carboplatin; paclitaxel

Ovarian Cancer Clinical Trial using DNIB0600A; carboplatin; bevacizumab [Avastin]

Genentech - Recruiting 18 years or older.
- A Phase Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of DNIB0600A in Combination With Carboplatin (With or Without Bevacizumab) in Patients With Platinum-Sensitive Ovarian Cancer.
DNIB0600A; carboplatin; bevacizumab [Avastin]

Colorectal Neoplasms Clinical Trial using Regorafenib (BAY73- 4506)

Bayer - Recruiting 18 years or older.
- An Open-label Phase III Study of Regorafenib in Patients With Metastatic Colorectal Cancer (mCRC) Who Have Progressed After Standard Therapy.
Regorafenib (BAY73- 4506)

Ovarian Cancer, Epithelial Tumors, Malignant, Fallopian Tube Canc Clinical Trial using DNIB0600A; pegylated liposomal doxorubicin

Genentech - Recruiting 18 years or older.
- A RANDOMIZED, OPEN-LABEL, MULTICENTER, PHASE II TRIAL EVALUATING THE SAFETY AND ACTIVITY OF DNIB0600A COMPARED TO PEGYLATED LIPOSOMAL DOXORUBICIN ADMINISTERED INTRAVENOUSLY TO PATIENTS WITH PLATINUM-RESISTANT OVARIAN CANCER.
DNIB0600A; pegylated liposomal doxorubicin

Ovarian Cancer, Pancreatic Cancer Clinical Trial using DMOT4039A

Genentech - Recruiting 18 years or older.
- A Phase I, Open Label Study of the Safety and Pharmacokinetics of Escalating Doses of DMOT4039A in Patients With Unresectable Pancreatic or Platinum Resistant Ovarian Cancer.
DMOT4039A

Esophageal Cancer Clinical Trial using early oral feeding

Henan Cancer Hospital - Recruiting 18 years to 80 years.
- Early Oral Feeding Following Thoracolaparoscopic Oesophagectomy in Patients With Esophageal Cancer: a Randomized Clinical Trial.
early oral feeding

Prostate Cancer Clinical Trial using GDC-0068; GDC-0980; placebo; abiraterone; prednisone

Genentech - Recruiting 18 years or older.
- A Phase Ib/II Study of GDC-0068 Or GDC-0980 With Abiraterone Acetate Versus Abiraterone Acetate in Patients With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy.
GDC-0068; GDC-0980; placebo; abiraterone; prednisone

Breast Cancer Clinical Trial using GDC-0032; Docetaxel; Paclitaxel

Genentech - Recruiting 18 years or older.
- A Phase Ib Open-Label, Dose-Escalation Study of the Safety and Pharmacology of GDC-0032 in Combination With Either Docetaxel or Paclitaxel in Patients With HER2-Negative, Locally Advanced or Metastatic Breast Cancer.
GDC-0032; Docetaxel; Paclitaxel

Gastric Cancer Clinical Trial using GDC-0068; Placebo; mFOLFOX6

Genentech - Recruiting 18 years or older.
- A Randomized, Phase II, Placebo Controlled Study of GDC-0068, an Inhibitor to Akt, in Combination With Fluoropyrimidine Plus Oxaliplatin in Patients With Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma.
GDC-0068; Placebo; mFOLFOX6

Non-Small Cell Lung Cancer Clinical Trial using GDC-0941; carboplatin; paclitaxel; bevacizumab; Placebo

Genentech - Recruiting 18 years or older.
- A Phase II, Double-Blind, Placebo-Controlled, Randomized Study Evaluating the Safety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without GDC-0941 in Patients With Previously Untreated Advanced or Recurrent Non-small Cell Lung Cancer.
GDC-0941; carboplatin; paclitaxel; bevacizumab; Placebo

Bladder Cancer Clinical Trial using Computed Tomography Urography (CTU); Intravenous Urography (IVU)

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Pilot Study Assessing the Technical Efficacy of Computed Tomography Urography (CTU) vs Intravenous Urography (IVU) With Particular Focus on Patients at Risk of Urothelial Tumors.
Computed Tomography Urography (CTU); Intravenous Urography (IVU)

Acute Leukemia Clinical Trial using FLT PET/CT; MRI

Masonic Cancer Center, University of Minnesota - Recruiting 18 years to 55 years.
- Positron Emission Tomography (PET) Imaging in Patients With High Risk Hematological Malignancies Receiving Total Body Irradiation (TBI) or Total Marrow Irradiation (TMI) as Part of a Hematopoietic Stem Cell Transplant.
FLT PET/CT; MRI

Metastatic Breast Cancer Clinical Trial using PF-05280014; Paclitaxel; Herceptin®

Pfizer - Recruiting 18 years or older.
- A Phase 3 Randomized, Double-Blind Study Of PF-05280014 Plus Paclitaxel Versus Trastuzumab Plus Paclitaxel For The First-Line Treatment Of Patients With HER2-Positive Metastatic Breast Cancer.
PF-05280014; Paclitaxel; Herceptin®

Hodgkin's Disease Clinical Trial using Gemcitabine; Fludarabine; Melphalan; Antithymocyte Globulin; Allogeneic Stem Cell Infusion; Tacrolimus; Filgrastim (G-CSF); Methotrexate

M.D. Anderson Cancer Center - Recruiting N/A to 65 years.
- Allogeneic Stem Cell Transplantation Followed By Adoptive Immunotherapy for Patients With Relapsed and Refractory Hodgkin's Disease.
Gemcitabine; Fludarabine; Melphalan; Antithymocyte Globulin; Allogeneic Stem Cell Infusion; Tacrolimus; Filgrastim (G-CSF); Methotrexate

Leukemia, Myelogenous, Chronic Clinical Trial using Nilotinib

M.D. Anderson Cancer Center - Recruiting 16 years or older.
- Therapy of Early Chronic Phase Chronic Myelogenous Leukemia (CML) With Oral Nilotinib.
Nilotinib

Bone Metabolism Biomarkers, Bone Mineral Density, or Physical Fit Clinical Trial using Vitamin D3; Physical Activity

University of Rochester - Recruiting 18 years or older.
- The Effect of High-Dose Vitamin D and Physical Activity on Bone Health in Breast Cancer Patients Receiving Hormonal Therapy.
Vitamin D3; Physical Activity

Confirmed Diagnosis of ß-thalassemia Major Clinical Trial using Autologous CD34+ cells transduced with TNS9.3.55

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase I Clinical Trial for the Treatment of ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene.
Autologous CD34+ cells transduced with TNS9.3.55

Metastatic Breast Cancer Clinical Trial using Anakinra plus Standard of Care

Baylor Research Institute - Recruiting 18 years to 80 years.
- Pilot Safety and Blood Immune Cell Transcriptional Profiling Study of Anakinra Plus the Physician's Chemotherapy Choice in Metastatic Breast Cancer Patients.
Anakinra plus Standard of Care

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, or Myelodys Clinical Trial using Allopurinol; Keppra; Busulfan; Cyclophosphamide; Cyclosporine A; Mycophenolate mofetil; Allogeneic hematopoietic stem cell transplant; Filgrastim; antithymocyte globulin

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 44 years.
- Busulfan and Cyclophosphamide Followed By Allogeneic Hematopoietic Cell Transplantation In Patients With Hematological Malignancies.
Allopurinol; Keppra; Busulfan; Cyclophosphamide; Cyclosporine A; Mycophenolate mofetil; Allogeneic hematopoietic stem cell transplant; Filgrastim; antithymocyte globulin

HER-2 Gene Amplification, Esophagus Cancer, Gastroesophageal Junc Clinical Trial using MM-111; Paclitaxel; Trastuzumab

Merrimack Pharmaceuticals - Recruiting 18 years or older.
- Randomized, Open Label, Phase 2 Study of MM-111 and Paclitaxel With Trastuzumab in Patients With HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach Who Have Failed Front Line Metastatic or Locally Advanced Therapy.
MM-111; Paclitaxel; Trastuzumab

HER2 Positive Breast Cancers Clinical Trial using ONT-380; T-DM1

Oncothyreon Inc. - Recruiting 18 years or older.
- A Phase 1b, Open-label Study to Assess the Safety and Tolerability of ONT-380 Combined With T-DM1.
ONT-380; T-DM1

Leukemia, or Myelodysplastic Syndromes Clinical Trial using filgrastim; busulfan; cyclosporine; fludarabine phosphate; melphalan; mycophenolate mofetil; umbilical cord blood transplantation

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 2 years.
- Hematopoietic Cell Transplantation in the Treatment of Infant Leukemia Using Double Umbilical Cord Transplantation.
filgrastim; busulfan; cyclosporine; fludarabine phosphate; melphalan; mycophenolate mofetil; umbilical cord blood transplantation

Osteosarcoma Clinical Trial using Tissue Procurement

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors.
Tissue Procurement

Leukemia Clinical Trial using sargramostim; busulfan; cyclophosphamide; dexamethasone; etoposide; bone marrow transplantation; hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; total-body irradiation

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 70 years.
- Autologous Peripheral Blood Stem Cell Transplant for Acute Non-Lymphocytic Leukemia (ANLL).
sargramostim; busulfan; cyclophosphamide; dexamethasone; etoposide; bone marrow transplantation; hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; total-body irradiation

Hodgkin's Lymphoma Clinical Trial using Panobinostat; Ifosfamide; Mesna; Carboplatin; Etoposide; Pegfilgrastim

M.D. Anderson Cancer Center - Recruiting 16 years or older.
- Phase I Study of Panobinostat Plus ICE Chemotherapy Followed by a Randomized Phase-II Study of ICE Compared With Panobinostat Plus ICE for Patients With Relapsed and Refractory Classical Hodgkin Lymphoma.
Panobinostat; Ifosfamide; Mesna; Carboplatin; Etoposide; Pegfilgrastim

Advanced Cancer Clinical Trial using crizotinib

Pfizer - Recruiting 18 years or older.
- A Phase I Study To Evaluate The Effect Of Hepatic Impairment On The Pharmacokinetics And Safety Of Crizotinib In Advanced Cancer Patients.
crizotinib

Metastatic Colorectal Cancer Clinical Trial using Metastases resection; Bevacizumab; 5 FU (5Fluorouracile); Oxaliplatine; Irinotecan

Cliniques universitaires Saint-Luc- Université Catholique de Louvain - Recruiting 18 years or older.
- Randomized Phase 2 Study Comparing Pathological Responses on Colorectal Cancer Metastases After Preoperative Treatment Combining Bevacizumab With FOLFOX or FOLFIRI.
Metastases resection; Bevacizumab; 5 FU (5Fluorouracile); Oxaliplatine; Irinotecan

Breast Cancer, or Lymphedema Clinical Trial using Supportive care (lymphedema education); Lymphedema Survey; bilateral upper extremities (BUE) measurements

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- Effect of Intensive Education on Breast Cancer Patient's Understanding of Lymphedema.
Supportive care (lymphedema education); Lymphedema Survey; bilateral upper extremities (BUE) measurements

Colon Cancer Clinical Trial

AHS Cancer Control Alberta - Recruiting 18 years or older.
- Thymidylate Synthase Polymorphisms as a Predictor of Toxicity to Capecitabine Based Adjuvant Chemotherapy in Colon Cancer Treatment.

Cancer Clinical Trial using anti-thymocyte globulin; rituximab; clofarabine; stem cell transplantation

Masonic Cancer Center, University of Minnesota - Recruiting N/A or older.
- Conditioning for Graft Failure After Hematopoietic Stem Cell Transplantation.
anti-thymocyte globulin; rituximab; clofarabine; stem cell transplantation

Hurler Syndrome Clinical Trial using IRT Laronidase

Masonic Cancer Center, University of Minnesota - Recruiting 6 Months to 3 years.
- Intrathecal Enzyme Replacement Therapy For Patients With Mucopolysaccharidosis Type I (Hurler Syndrome).
IRT Laronidase

Dyskeratosis Congenita, or Aplastic Anemia Clinical Trial using Campath 1H; Cyclophosphamide; Fludarabine; Total Body Irradiation; Stem Cell Transplantation; antithymocyte globulin; Methylprednisolone

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 70 years.
- Hematopoietic Stem Cell Transplant For Patients With Dyskeratosis Congenita and Severe Aplastic Anemia.
Campath 1H; Cyclophosphamide; Fludarabine; Total Body Irradiation; Stem Cell Transplantation; antithymocyte globulin; Methylprednisolone

Acute Myelogenous Leukemia Clinical Trial using Fludarabine; Cytarabine; G-CSF (Filgrastim, Neupogen); Idarubicin

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Phase 2 Study of Fludarabine, Cytarabine, Filgrastim and Idarubicin in Newly Diagnosed Core Binding Factor Associated Acute Myelogenous Leukemia.
Fludarabine; Cytarabine; G-CSF (Filgrastim, Neupogen); Idarubicin

Leukemia, Lymphoma, or Multiple Myeloma and Plasma Cell Neoplasm Clinical Trial using busulfan; cyclophosphamide; Stem cell infusion; Total body irradiation

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 55 years.
- Unrelated or Partially Matched Allogeneic Donor Stem Cells for Lymphoma, Myeloma, and Chronic Lymphocytic Leukemia.
busulfan; cyclophosphamide; Stem cell infusion; Total body irradiation

Lung Neoplasm, or Cell Hypoxia Clinical Trial using 18F-FAZA; 18F-Fluorodeoxyglucose (18F-FDG)

AHS Cancer Control Alberta - Recruiting 18 years or older.
- A Study to See if a New Type of Imaging Can Help Our Understanding of the Course of Non-small Cell Lung Cancer in Patients Undergoing Treatment With Radiotherapy or Chemoradiotherapy.
18F-FAZA; 18F-Fluorodeoxyglucose (18F-FDG)

Rectal Cancer Clinical Trial using folfox; short course Radiotherapy

Yonsei University - Recruiting 18 years or older.
- A Phase 2 Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis.
folfox; short course Radiotherapy

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas.
Gemcitabine

Juvenile Myelomonocytic Leukemia Clinical Trial using Stem Cell Transplant

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 18 years.
- Hematopoietic Cell Transplantation in Children With Juvenile Myelomonocytic Leukemia.
Stem Cell Transplant

Colon Cancer Clinical Trial using Questionnaire

M.D. Anderson Cancer Center - Recruiting 14 years or older.
- Prognostic Molecular and Environmental Factors in High-Risk Stage II and Stage III Colon Cancer Patients.
Questionnaire

Childhood Germ Cell Tumor, Ovarian Cancer, or Teratoma Clinical Trial using carboplatin; etoposide; ifosfamide; paclitaxel; thiotepa; autologous hematopoietic stem cell transplantation; Mesna; filgrastim

Masonic Cancer Center, University of Minnesota - Recruiting 10 years to 69 years.
- Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors.
carboplatin; etoposide; ifosfamide; paclitaxel; thiotepa; autologous hematopoietic stem cell transplantation; Mesna; filgrastim

Healthy Clinical Trial using Mexican or American foods

Fred Hutchinson Cancer Research Center - Recruiting 18 years to 45 years.
- Metabolic Response to Western vs. Indigenous Diets in Hispanic Women.
Mexican or American foods

Chondrosarcoma Clinical Trial using Proton Beam Therapy

M.D. Anderson Cancer Center - Recruiting N/A or older.
- Phase II Evaluation of Proton Beam Therapy for Skull Base Chondrosarcoma.
Proton Beam Therapy

Advanced Cancer Clinical Trial using Questionnaire; Actigraph

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- The Brief Sleep Disturbance Scale: Measuring Sleep Disturbance Among Cancer Patients.
Questionnaire; Actigraph

Prostate Cancer Clinical Trial using Muscadine Plus Grape Skin Extract

Johns Hopkins University - Recruiting 18 years or older.
- Phase I/II Study of Safety and Efficacy of Muscadine Plus (MPX) in Men With Prostate Cancer: a Randomized,Double-blind,Placebo Controlled Study of the Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer.
Muscadine Plus Grape Skin Extract

Hurler Syndrome Clinical Trial using Laronidase

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 14 years.
- Pilot Study of Administration of Intravenous Laronidase Following Allogeneic Transplantation for Hurler Syndrome.
Laronidase

Acute Lung Injury, Acute Respiratory Distress Syndrome, or Respir Clinical Trial using IV Ganciclovir; Placebo

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- A Randomized Double-Blind Placebo-Controlled Trial of Ganciclovir/Valganciclovir for Prevention of Cytomegalovirus Reactivation in Acute Injury of the Lung and Respiratory Failure (The GRAIL Study).
IV Ganciclovir; Placebo

Advanced Cancer Clinical Trial using LY2835219; Fulvestrant

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 1 Study of a CDK 4/6 Dual Inhibitor in Participants With Advanced Cancer.
LY2835219; Fulvestrant

Epithelial Cancer Clinical Trial using Lapatinib; Radiation therapy

Virginia Commonwealth University - Recruiting 18 years or older.
- A Randomized Study of Lapatinib With Radiation Versus Radiation Alone in Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease.
Lapatinib; Radiation therapy

Retroviridae Infections, or Cancer Clinical Trial using Blood Tests; Questionnaires

M.D. Anderson Cancer Center - Recruiting N/A or older.
- Long-Term Follow-Up Study of Recipients of Gene Transfer Research Protocols.
Blood Tests; Questionnaires

Esophageal Cancer Clinical Trial using wireless pulse oximeter (Wipox)

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- A Prospective Trial to Evaluate Whether Variations in Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy.
wireless pulse oximeter (Wipox)

Non-Hodgkin's Lymphoma, Multiple, Mycosis Fungoides, Hodgkin's Ly Clinical Trial using Dasatinib

Barbara Ann Karmanos Cancer Institute - Recruiting 18 years or older.
- Phase I/II Study of Dasatinib in Recipients of Autologous Stem Cell Transplantation for Hematologic Malignancies..
Dasatinib

Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Myeloid Leukemia, Mul Clinical Trial using Dasatinib; laboratory biomarker analysis

Barbara Ann Karmanos Cancer Institute - Recruiting 18 years or older.
- Phase I/II Study of Dasatinib in Recipients of Allogeneic Stem Cell Transplantation for Hematologic Malignancies..
Dasatinib; laboratory biomarker analysis

Breast Cancer Clinical Trial using doxorubicin hydrochloride; enalapril maleate

Masonic Cancer Center, University of Minnesota - Recruiting 18 years or older.
- The Effect of Enalapril on Doxorubicin Exposure in Adjuvant Breast Cancer Treatment.
doxorubicin hydrochloride; enalapril maleate

Breast Cancer Clinical Trial using Paclitaxel; BKM120 matching placebo; BKM120

Novartis - Recruiting 18 years or older.
- A Randomized, Double-blind, Placebo Controlled, Phase II/III Study of BKM120 Plus Paclitaxel in Patients With HER2 Negative Inoperable Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Pathway Activation..
Paclitaxel; BKM120 matching placebo; BKM120

Colorectal Cancer, Breast Cancer, Coronary Heart Disease, or Diab Clinical Trial using risk assessment survey; decision support for providers for prevention based on risk

Brigham and Women's Hospital - Recruiting 18 years to 75 years.
- Health Information Technology (HIT) Enhanced Family History Documentation and Management in Primary Care.
risk assessment survey; decision support for providers for prevention based on risk

Non-small Cell Lung Carcinoma Clinical Trial using chemotherapy

Yonsei University - Recruiting 18 years or older.
- .
chemotherapy

Acinar Cell Adenocarcinoma of the Pancreas, Adenocarcinoma of the Clinical Trial using oxaliplatin; irinotecan hydrochloride; leucovorin calcium; fluorouracil; laboratory biomarker analysis

University of Chicago - Recruiting 18 years or older.
- A Genotype-guided Dosing Study of mFOLFIRINOX in Previously Untreated Patients With Advanced Gastrointestinal Malignancies.
oxaliplatin; irinotecan hydrochloride; leucovorin calcium; fluorouracil; laboratory biomarker analysis

Metastatic Advanced Gastric Cancer Clinical Trial using Docetaxel 60 mg/m2, epirubicin 60 mg/m2, q3wks

Yonsei University - Recruiting 20 years or older.
- .
Docetaxel 60 mg/m2, epirubicin 60 mg/m2, q3wks

Advanced Cancer, Metastatic Cancer, Lymphoma, Metastatic Breast C Clinical Trial using LY3023414; Midazolam; Letrozole

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 1 First-in-Human Dose Study of LY3023414 in Patients With Advanced Cancer.
LY3023414; Midazolam; Letrozole

CD20+, B-cell Lymphomas, Mantle Cell Lymphoma, Non-Mantle Cell Lo Clinical Trial using Everolimus and Rituximab

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Trial of Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in CD20+, B-cell Lymphomas and Hodgkin's Lymphoma.
Everolimus and Rituximab

Metastatic Colorectal Cancer Clinical Trial using Metastases Resection; 5-Fluorouracile; leucovorin L; Oxaliplatin; Irinotecan; Cetuximab

Cliniques universitaires Saint-Luc- Université Catholique de Louvain - Recruiting 18 years or older.
- Randomised Phase 2 Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors.
Metastases Resection; 5-Fluorouracile; leucovorin L; Oxaliplatin; Irinotecan; Cetuximab

HER2-positive Breast Cancer, Recurrent Breast Cancer, Stage IA Br Clinical Trial using laboratory biomarker analysis; pharmacological study; questionnaire administration; fluorine F 18-clevudine; positron emission tomography/computed tomography

University of Southern California - Recruiting 18 years or older.
- Development of an In Vivo Cell Proliferation Marker for PET Assessment of Chemotherapeutic Response in Cancer.
laboratory biomarker analysis; pharmacological study; questionnaire administration; fluorine F 18-clevudine; positron emission tomography/computed tomography

Colorectal Neoplasms Clinical Trial using Samples and follow up

Centre Hospitalier Universitaire de NÄ«mes - Recruiting 18 years or older.
- Invasiveness and Chemoresistance of Cancer Stem Cells in Colon Cancer: Molecular Characterization and Implications for Therapeutic Strategies.
Samples and follow up

Rectal Cancer Clinical Trial using Surgery after 11 weeks of delay after chemoradiotherapy.; Surgery after 7 weeks of delay after chemoradiotherapy

Assistance Publique - Hôpitaux de Paris - Recruiting 18 years or older.
- Randomized Control Trial Comparing the Impact of a Lengthening of the Interval Between the Radiochemotherapy and Surgery (7 Weeks vs. 11 Weeks) on Complete Pathological Response in Rectal Cancer.
Surgery after 11 weeks of delay after chemoradiotherapy.; Surgery after 7 weeks of delay after chemoradiotherapy

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Adenocarcinoma of the Pancreas After Preoperative Chemoradiation Therapy.
Gemcitabine

Solid Tumor, Ovarian Cancer, Non-small Cell Lung Cancer, Chronic Clinical Trial

Cancer Centre of Monoclonal Therapy, LLC - Recruiting 18 years or older.
- Prognostic Potential of Cell Surface Markers and Pim Kinases in Patients With Selected Refractory or Relapsed Hematologic Malignancies or Solid Tumors.

Pancreatic Diseases, Pancreatic Neoplasms, or Pancreatitis Clinical Trial using No interventions, this is an observational study

Aalborg Universityhospital - Recruiting 18 years or older.
- Cell-free DNA Promoter Hypermethylation in Plasma From Patients With Pancreatic Adenocarcinoma, Compared to Patients With Pancreatitis and Pancreatitis and Patients Screened for, But Not Having Pancreatic Adenocarcinoma.'.
No interventions, this is an observational study

Relapsed B-Cell Acute Lymphoblastic Leukemia Clinical Trial using leukapheresis or collection of PBMCs; cyclophosphamide; modified T cells

Memorial Sloan-Kettering Cancer Center - Recruiting N/A to 26 years.
- A Phase I Trial of Autologous T-Lymphocytes Genetically Targeted to the B-Cell Specific Antigen CD19 in Pediatric and Young Adult Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia.
leukapheresis or collection of PBMCs; cyclophosphamide; modified T cells

Colon Cancer, Rectum Cancer, or Liver Metastases Clinical Trial using Lap+Lus

Odense University Hospital - Recruiting 18 years or older.
- The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum: A Prospective Randomized Trial.
Lap+Lus

Breast Cancer Clinical Trial

University of Kentucky - Recruiting 18 years to 65 years.
- A Pilot Study of Working Women and Breast Cancer.

Prostate Cancer Clinical Trial using Enzalutamide

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer (CRPC) With Correlative Assessment of Androgen Receptor (AR) Signaling and Whole-exome and Transcriptome Sequencing.
Enzalutamide

Hereditary Pancreatitis, or Hereditary Pancreatic Cancer Clinical Trial using MRI

Karolinska University Hospital - Recruiting 18 years or older.
- Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.
MRI

Malignant Neoplasm Clinical Trial using fluorine F 18 d-FMAU; positron emission tomography; computed tomography

University of Southern California - Recruiting 19 years or older.
- 18F-FMAU for Imaging in Cancer Patients.
fluorine F 18 d-FMAU; positron emission tomography; computed tomography

Stage III Non-small Cell Lung Cancer Clinical Trial using 1 MRI scan

UMC Utrecht - Recruiting 18 years or older.
- MRI for Radiotherapy Treatment Planning of Stage III NSCLC: an MRI Optimization Study in Healthy Volunteers and Patients.
1 MRI scan

Prostate Cancer Clinical Trial using Robot-assisted prostate biopsy

Sidney Kimmel Comprehensive Cancer Center - Recruiting 35 years to 75 years.
- .
Robot-assisted prostate biopsy

Carcinoma, Squamous Cell, Mouth Neoplasms, Oropharyngeal Neoplasm Clinical Trial

Centre Hospitalier Universitaire de NÄ«mes - Recruiting 30 years to 80 years.
- Pharmacogenetic and Pharmacokinetic Aspects of the Response to Chemotherapy Induction Using Docetaxel, Cisplatin and 5-Fluorouracile (TPF)in ORL Cancers.

Diffuse Large B-cell Lymphoma, or Follicle Center Lymphoma Clinical Trial using Zevalin (ibritumomab tiuxetan)

Spectrum Pharmaceuticals, Inc - Recruiting 60 years or older.
- A Phase 3, Open-label, Multicenter, Randomized Study of Sequential Zevalin (Ibritumomab Tiuxetan) Versus Observation in Patients at Least 60 Years of Age With Newly Diagnosed Diffuse Large B-cell Lymphoma in PET-negative Complete Remission After R-CHOP or R-CHOP-like Therapy.
Zevalin (ibritumomab tiuxetan)