Ethicon, Inc. - Recruiting 18 years or older. - A Non-Investigational Post-Market Trial Using EVARRESTT Fibrin Sealant Patch as an Adjunct to Hemostasis in Soft Tissue Bleeding During Intra-Abdominal, Retroperitoneal, Pelvic and Non-Cardiac Thoracic Surgery.
Paion UK Ltd. - Recruiting 18 years or older. - A Randomized, Single-blind Phase II Study Evaluating the Efficacy, Safety and Pharmacokinetics of Remimazolam in General Anesthesia in Adult Patients Undergoing Cardiac Surgery, Including Follow-up Sedation in the PACU/ICU.
Rigshospitalet, Denmark - Recruiting 18 years or older. - CardioPAT Project - Reducing the Need for Allogenic Blood Transfusion After On-pump Cardiac Surgery With Intra- and Postoperative Use of a New Device: a Randomized Trial.
University Hospital, Basel, Switzerland - Recruiting 18 years or older. - Novel Biomarkers (TIMP-2 and IGFBP7) of Tubular Renal Cell Damage for the Prediction of the Cardiac Surgery Associated Acute Kidney Injury (CSA-AKI) - A Feasibility Study.
University of Erlangen-Nrnberg Medical School - Recruiting 40 years to 85 years. - Phase 4 Study of Postoperative Pain Therapy With Hydromorphone Using Patient-Controlled Target-Controlled Infusion (TCI-PCA) vs. Patient-Controlled Analgesia (PCA) After Elective Cardiac Surgery.
INO Therapeutics - Recruiting N/A to 80 years. - Examination of Safety and Effectiveness of IK-3001 (Nitric Oxide for Inhalation) in Japanese Subjects With Pulmonary Hypertension Associated With Cardiac Surgery - Multi-Center, Open-Label, Clinical Study.
Massachusetts General Hospital - Recruiting 18 years or older. - Understanding 'Heparin Resistance' in Cardiac Surgery: Altered Heparin Responsiveness and Its Association With Acute Inflammatory Reactions.
University of Belgrade - Recruiting N/A or older. - Prospective Case-control Study on the Incidence of Incisional Hernias at 12 Months After Closure of Midline Laparotomies in Patients Treated for Abdominal Aortic Aneurysm.
Emory University - Recruiting 18 years to 80 years. - Prospective Study Aim to Determine the Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Cardiac Surgery Patients With Perioperative Hyperglycemia.
Rennes University Hospital - Recruiting 18 years or older. - Hemodynamic Indices Predictive of a Beneficial Response to Fluid Expansion in Case of Hemodynamic Failure After Cardiac Surgery With Altered Preoperative Ejection Fraction (LVEFó45%): Sensibility and Specificity of Respiratory Variations of Pulse Pressure (?PP), Photoplethysmography (?POP), Perfusion Index (PVI), End Expiratory Occlusion Test, and Passive Leg Rising Test, Compared With Fluid Expansion..
University of Pennsylvania - Recruiting 18 years or older. - The Effect of Standard vs Aggressive Dosing Regimens for Epsilon-aminocaproic Acid on a Quantifiable Parameter of Fibrinolysis as Measured by Thromboelastography.
Haukeland University Hospital - Recruiting 18 years to 80 years. - Ringer`s Acetat Versus Balanced Hydroxyethyl-starch as Primesolution in the Heart-lung Maschine During Cardio-pulmonary-bypass. Postoperatively Fluid Balance and Cardiac Function.
Thrasos Innovation, Inc. - Recruiting 18 years to 85 years. - A Multi-Center, Parallel-Group, Randomized, Double Blind, Adaptive Study Investigating the Safety and Efficacy of THR-184 in Patients at Increased Risk of Developing Cardiac Surgery Associated-Acute Kidney Injury (CSA-AKI).
NHS Greater Glasgow and Clyde - Recruiting N/A to 5 years. - Effect of Remote Ischaemic Preconditioning in Cardiac Dysfunction and End-organ Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Children..
Bambino Ges Hospital and Research Institute - Recruiting N/A to 10 years. - Phase III Study of Furosemide Continuous Infusion Versus Ethacrynic Acid Continuous Infusion in Children Undergoing Cardiac Surgery: Randomized Double Blind Controlled Clinical Trial.
University of Alberta - Recruiting 18 years or older. - GLutamine Enterally After carDiac Surgery for Inflammation Attenuation and ouTcOme impRovement (GLADIATOR): A Phase II Randomized, Blinded, Placebo-Controlled Trial.
National Taiwan University Hospital - Recruiting 18 years or older. - Early Diagnosis of Postoperative Acute Renal Failure - Using Biomarker to Predict the Outcome of Cardiac Surgery Associated Acute Kidney Injury.
Chinese PLA General Hospital - Recruiting 18 years to 75 years. - A Prospective,Randomized, Placebo-Controlled Study of Intramyocardial Injection of Autologous Bone-Marrow Mononuclear Cells in Patients With Severe, Chronic Ischemic Heart Disease Undergoing Coronary Bypass Surgery.
bone marrow mononuclear cells injection; placebo intramyocardial injection
University of Bari - Recruiting 18 years to 80 years. - Effects of the Administration Of Antithrombin on the Coagulation Status and on the Inflammatory Response in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery.
Medical University of Vienna - Recruiting 19 years to 90 years. - Is Global Longitudinal Peak Systolic Strain (GLPSS) Derived From Transesophageal Echocardiography a Reliable Measure of Systolic Function? A Multicenter-Study to Compare GLPSS With Ejection Fraction Derived From Biplane Simpson's Method on TTE and TEE in Patients Undergoing Elective Cardiac and Non-Cardiac Surgery.
St. Michael's Hospital, Toronto - Recruiting 18 years or older. - A Phase II, Double Blind Randomized Controlled Trial to Determine the Safety and Efficacy of 12.5mg of Oral Sildenafil (Viagra) Compared to Placebo to Decrease Pulmonary Hypertension in Cardiac Patients After Cardiopulmonary Bypass.
Instituto de Ciencias del Corazon - Recruiting 18 years or older. - Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study: a Multicenter, Prospective, Randomized Trial Comparing the State-of-the-Art Therapeutic Strategy Versus Early Surgery Strategy in Infective Endocarditis.