University of British Columbia - Recruiting 16 years to 90 years. - Ultrasound Guided Sciatic Perineural Catheter vs Surgically Placed Sciatic Stump Catheter for Below Knee Amputations: Is There A Difference in Patient Outcomes.
Pfizer - Recruiting 18 years to 75 years. - A Randomized Double Blind Placebo Controlled Parallel Group Study of the Efficacy and Safety of Concomitant Administration of Celecoxib and Pregabalin Compared With Celecoxib Monotherapy, in Patients With Chronic Low Back Pain Having a Neuropathic Component.
Teva Pharmaceutical Industries - Recruiting 18 years to 80 years. - A 6-Month, Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) at 15 to 90 mg Every 12 Hours for Relief of Moderate to Severe Pain in Patients With Chronic Low Back Pain Who Require Opioid Treatment for an Extended Period of Time.
Grnenthal GmbH - Recruiting 18 years or older. - An Open-label, Multi-site Trial to Describe the Safety and Tolerability of Oral Cebranopadol Administered for 26 Weeks in Subjects With Cancer-related Pain Who Have Completed Treatment in the KF6005/07 Trial..
National Institutes of Health Clinical Center (CC) - Recruiting 6 years or older. - Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Young Adults With Chronic Illness and Their Parents.
Grnenthal GmbH - Recruiting 18 years or older. - Efficacy, Safety, and Tolerability of Oral Cebranopadol Versus Morphine Sulfate PR in Subjects With Chronic Moderate to Severe Pain Related to Cancer..
University of Indianapolis - Recruiting 20 years to 60 years. - Astymr Treatment Compared With Eccentric Exercise in the Management of Chronic Mid-substance Achilles Tendinopathy: A Multisite a Randomized Controlled Trial.
Universidad de Almeria - Recruiting 18 years to 60 years. - Effects of Myofascial Soft Tissue Release and Mobilization With Impulse Technique Torsion in Subjects With Chronic Non-specific Low Back Pain: A Randomized Clinical Trial.
Myofascial Soft Tissue Release; Mobilization with impulse technique.
University of Nove de Julho - Recruiting 40 years to 80 years. - Influence of an Exercise Program for Trunk Stabilization Performed in Stable and Unstable Surfaces for Chronic Low Back Pain: Single-blind, Randomized Controlled Clinical Trial..
University of Alabama at Birmingham - Recruiting 19 years or older. - Randomized Single Blinded Control Trial Comparing EUS Guided Celiac Plexus Block (CPB) Versus Sham Treatment for Pain Management in Small Duct Chronic Pancreatitis.
Purdue Pharma LP - Recruiting 18 years or older. - A Randomized, Double-blind, Double-dummy, Placebo-controlled, Active-controlled, Parallel-group, Multicenter Trial of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess the Analgesic Efficacy (Compared to Placebo) and the Management of Opioid-induced Constipation (Compared to Oxycodone Controlled-release Tablets (OXY)) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain and a History of Opioid-induced Constipation Who Require Around-the-clock Opioid Therapy.
Kimberly-Clark Corporation - Recruiting 21 years or older. - A Prospective, Randomized, Multi-Center, Open-Label Clinical Trial Comparing Disc Biacuplasty With Medical Management for Discogenic Lumbar Back Pain.
Coastal Orthopedics & Sports Medicine - Recruiting 18 years or older. - A Prospective, Single Center, Double Blind, Randomized, Sham Controlled, Crossover Study to Evaluate the Clinical Efficacy of Radiofrequency Nerve Ablation Using Simplicity III Versus Sham for the Treatment of Chronic Low Back Pain Associated With Sacroiliac Joint Dysfunction.
SI-BONE, Inc. - Recruiting 21 years to 70 years. - A Multicenter Randomized Controlled Post-market Clinical Follow-up Trial Comparing the Effectiveness and Safety of the iFuse Implant Systemr Versus Conservative Management for Patients With Chronic, Disabling SI Joint Pain..
MedtronicNeuro - Recruiting 18 years or older. - Post-market, Randomized, Controlled, Prospective Study Evaluating a Treatment Conversion to Low Dose Intrathecal Morphine (IT) From Conventional Medical Management (CMM) for Maintenance of Pain Control and Improvement of Opioid-related Side Effects. (CONVERT Targeted Drug Delivery [TDD]).
SynchroMed Infusion System and Intrathecal Morphine Sulfate
Collegium Pharmaceutical, Inc. - Recruiting 18 years to 75 years. - A Phase 3, Multi-Center, Randomized, Double-blind, Placebo-Controlled, Safety, Tolerability, and Efficacy Study of Oxycodone DETERxT Versus Placebo in Opioid-Experienced and Opioid-Naive Subjects With Moderate-to-Severe Chronic Low Back Pain.
University of Sao Paulo General Hospital - Recruiting 20 years to 60 years. - Effectiveness of Acupuncture and Electroacupuncture in Patients With Chronic Nonspecific Low Back Pain: Randomized Clinical Trial.
University Hospital of Ferrara - Recruiting 18 years to 75 years. - Effects of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Orofacial Pain Unresponsive to Conventional Treatment. A Randomized Controlled Trial..
Jazz Pharmaceuticals - Recruiting 18 years or older. - Patient Registry of Intrathecal Ziconotide Management (PRIZM): An Open-Label, Long Term, Multi-Center, Observational Study of PRIALTr (Ziconotide) Solution, Intrathecal Infusion, in Patients With Severe Chronic Pain.
GW Pharmaceuticals Ltd. - Recruiting 18 years or older. - A Double Blind, Randomized, Placebo Controlled, Parallel Group Study of Sativexr in Relieving Persistent Pain in Patients With Advanced Cancer, Who Experience Inadequate Analgesia During Optimized Chronic Opioid Therapy..
Hpital Ambroise Par - Recruiting 18 years to 60 years. - Comparison of the Efficacy of Repetitive Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation of the Motor Cortex in Patients With Neuropathic Pain Due to Chronic Radiculopathy.
GW Pharmaceuticals Ltd. - Recruiting 18 years or older. - A Double Blind, Randomized, Placebo-controlled, Parallel Group Study of Sativexr Oromucosal Spray (Sativexr; Nabiximols) as Adjunctive Therapy in Relieving Uncontrolled Persistent Chronic Pain in Patients With Advanced Cancer, Who Experience Inadequate Analgesia During Optimized Chronic Opioid Therapy.
Clobetasol Oral Rinse; Chronic GVHD organ staging; Assessment of Oral GVHD; Numeric rating scales for oral pain; Oral Global Scale; Painometer (POM) Assessment; Oral Health Impact Profile-OHIP-14; Biopsy of buccal mucosa; Short ACTH stimulation test
IRCCS Policlinico S. Matteo - Recruiting 60 years or older. - A COMPARATIVE STUDY BETWEEN TWO PHARMACOLOGICAL ASSOCIATIONS OXYCODONE/NALOXONE AND CODEINE / PARACETAMOL IN TREATMENT OF MODERATE-SEVERE CHRONIC PAIN DUE TO OSTEOARTHRITIS OF KNEE AND/OR HIP.
Grnenthal GmbH - Recruiting 18 years to 80 years. - Efficacy, Safety and Tolerability of Multiple Doses of Oral Cebranopadol in Subjects With Moderate to Severe Chronic Pain Due to Diabetic Peripheral Neuropathy..
GW Pharmaceuticals Ltd. - Recruiting 18 years or older. - A Multicenter, Non-comparative, Open-label Extension Study to Assess the Long Term Safety of Sativexr Oromucosal Spray (Nabiximols) as Adjunctive Therapy in Patients With Uncontrolled Persistent Chronic Cancer-related Pain.
Synergy Pharmaceuticals Inc. - Recruiting 18 years to 75 years. - A Randomized, 4-Week, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Assess the Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) in Patients With Non-malignant Chronic Pain Receiving Opioid Therapy.
Assistance Publique - Hpitaux de Paris - Recruiting 18 years to 60 years. - Effectiveness of a Short, Intensive and Standardised Spa Therapy for Subacute and Chronic Low Back Pain on Return to Work for Patients in Sick Leave From 4 to 24 Weeks Duration : a Randomized Controlled Trial Using a Modified Zelen Method.
Spa therapy, exercise and educational therapy; Usual care
Assistance Publique - Hpitaux de Paris - Recruiting 18 years to 60 years. - Evaluation of the Analgesic Effect of a Prototype Device of Virtual Reality in a Population of Patients With Chronic Low Back Pain. A Randomized Controlled Trial Using a Modified ZELEN Method.
KK Women's and Children's Hospital - Recruiting 21 years to 70 years. - Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain- Functional Brain Imaging, Quantitative Sensory Testing, Psychological and Genetic Screening: Prospective Cohort Study.
Purdue Pharma LP - Recruiting 18 years or older. - A Randomized, Double-blind, Double-dummy, Placebo-controlled, Active-controlled, Parallel-group, Multicenter Trial of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess the Analgesic Efficacy (Compared to Placebo) and the Management of Opioid-induced Constipation (Compared to Oxycodone Controlled-release Tablets (OXY)) in Opioid-experienced Subjects With Uncontrolled Moderate to Severe Chronic Low Back Pain and a History of Opioid-induced Constipation Who Require Around-the-clock Opioid Therapy.
Hospital Vall d'Hebron - Recruiting 18 years to 70 years. - Clinical Trial, Randomized, Controlled, Parallel, to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed With Chronic Fatigue Syndrome..
Taipei Medical University - Recruiting 20 years to 85 years. - Therapeutic Effects of Monochromatic Infrared Energy Therapy on Patients With Chronic Low Back Pain: A Double-Blind, Randomized, Placebo-Controlled Study.
Hospital de Clinicas de Porto Alegre - Recruiting 18 years or older. - Effect of Transcranial Direct Current Stimulation and Electro Acupuncture in Pain, Functional Capability and Cortical Excitability in Patients With Osteoarthritis..
tDCS and EAC sham; tDCS sham and EAC sham; tDCS sham and EAC; tDCS and EAC
Radboud University - Recruiting 18 years or older. - ë9-THC (Namisolr) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain: a Randomized, Double-blinded, Placebo-controlled, Parallel Design.
Florida State University - Recruiting 18 years or older. - Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy: Exploration of Cognitive, Affective, and Physiological Mechanisms.
Mindfulness-Oriented Recovery Enhancement; Conventional Support Group (SG)
Luzerner Kantonsspital - Recruiting 18 years or older. - Investigating the Effect of Intra-operative Infiltration With Local Anaesthesia on the Development of Chronic Postoperative Pain After Inguinal Hernia Repair. A Randomized Placebo Controlled Triple Blinded and Group Sequential Study Design.
Infiltration with Saline; Infiltration with Bupivacaine
University of California, Irvine - Recruiting 18 years or older. - Double Blind, Placebo Controlled, Crossover Pilot Trial on the Effect of Optically Modified Polyethylene Terephthalate Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain.
specific mattress cover, placebo garment mattress cover
Smerud Medical Research International AS - Recruiting 18 years or older. - Study of the Efficacy, Safety and Tolerability of Topical 2PX (Strontium Chloride Hexahydrate) in Patients With Chronic, Moderate-to-severe Lower Limb Post-amputation Stump Pain..
University Health Network, Toronto - Recruiting 18 years to 65 years. - Use of the Cannabinoid Nabilone for the Promotion of Sleep in Chronic, Non-Malignant Pain Patients: A Placebo-Controlled, Randomized, Crossover Insomnia Pilot Study.
iTech Medical, Inc. - Recruiting 18 years to 62 years. - Multi-Center, Multi-National Study to Demonstrate That Muscle Pattern Recognition is a Reliable and Valid Evaluation Tool for Patients Who Present With Acute, Sub-Acute, or Chronic Symptoms of Neck or Back Pain of a Musculoskeletal Origin.