Brown University - Recruiting 18 years or older. - A Dose Finding Study of Eribulin Mesylate and Cetuximab For Patients With Advanced Head and Neck and Colon Cancer With an Expansion Cohort For Head and Neck Cancer: A Brown University Oncology Research Group Study.
NCIC Clinical Trials Group - Recruiting 18 years or older. - A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE).
exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment
Centre Hospitalier Universitaire de NÄ«mes - Recruiting 18 years or older. - Invasiveness and Chemoresistance of Cancer Stem Cells in Colon Cancer: Molecular Characterization and Implications for Therapeutic Strategies.
Odense University Hospital - Recruiting 18 years or older. - The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum: A Prospective Randomized Trial.
Georgetown University - Recruiting 18 years or older. - A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLOFOX or FOLFIRI in Patients With Newly Diagnosed Ras Mutant Positive Metastatic Colorectal Cancer or Patients With Ras Mutant Positive Colorectal Cancer Who Have Just Completed a First Line Therapy With an Oxaliplatin or Irinotecan Plus Fluoropyrimidine and Bevacizumab Containing Regimen.
Hoffmann-La Roche - Recruiting 18 years or older. - Non-interventional Local Study to Describe the Safety, Tolerability and Efficacy of Bevacizumab in Combination With Standard Chemotherapy Regimens as First Line in Patients With Metastatic Cancer of the Colon or the Rectum.
Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older. - Adherence to Comprehensive, Multi-Organ Screening Recommendations in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients.
questionnaires, telephone interview, optional tube of blood drawn; questionnaires, telephone interview and optional tub of blood drawn
National Institutes of Health Clinical Center (CC) - Recruiting 60 years or older. - A Multicenter Phase II Study of Enhancement of Immune Reconstitution and Vaccine Responses With Administration of Glyco-Recombinant Human IL-7 in Older Subjects Following Chemotherapy.
Glycosylated Recombinant Human Interleukin-7; Diphtheria-Tetanus Vaccine; Polio Vaccine; Pneumaococcal Vaccine; Hepatitis A Vaccine; Hepatitis B Vaccine; Influenza Vaccine; PhiX 174
AbbVie - Recruiting 18 years or older. - A Randomized, Placebo-Controlled Crossover Study to Evaluate the Effect of Veliparib (ABT-888) on Cardiac Repolarization in Subjects With Relapsed or Refractory Solid Tumors.
Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older. - ICARuS (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Single-center, Randomized Phase II Trial of Early Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis.
Cytoreductive Surgery; HIPEC with Mitomycin-C; EPIC with FUDR and Leucovorin
Southwest Oncology Group - Recruiting 18 years or older. - A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES).
Onkovis GmbH - Recruiting N/A or older. - Open, Multicenter Observational Study of Oxaliplatin Utilized in Combination Therapy for Adjuvant Treatment of Colon Carcinoma of Stage III After Complete Removal of the Primary Tumor and for Treatment of Metastasizing Colorectal Carcinoma..
Swiss Group for Clinical Cancer Research - Recruiting 18 years or older. - Clinical Function After Total Mesorectal Excision and Rectal Replacement. A Prospective Randomized Trial Comparing Side-to-End Anastomosis, Colon-J-Pouch and Straight Coloanal Anastomosis.
5 cm colon-J-pouch; side-to-end anastomosis; straight coloanal anastomosis
Ottawa Hospital Research Institute - Recruiting 18 years or older. - A Multicentre Randomized Controlled Trial of the Use of Extended Peri-Operative Low Molecular Weight Heparin to Improve Cancer Specific Survival Following Surgical Resection of Colon Cancer.
M.D. Anderson Cancer Center - Recruiting 18 years or older. - Comparative Study of Oncologist Recommended, Home-Based Exercise Program and Relaxation Training for Physical Functioning and Symptom Control in Colon Cancer Patients.
Exercise Program; Telephone-based intervention; Counseling intervention; Questionnaire administration; Relaxation Program
Ohio State University Comprehensive Cancer Center - Recruiting 18 years or older. - A Phase II Study of Panitumumab in Combination With FOLFIRI After Progression on FOLFIRI Plus Bevacizumab in KRAS(Kirsten Rat Sarcoma) Wild-Type Metastatic Colorectal Cancer..
Samsung Medical Center - Recruiting 18 years or older. - A Randomized Phase III Study Investigating the Role of Oxaliplatin Duration (3 Months Versus 6 Months) in Modified FOLFOX-6 or CAPOX Regimen as Adjuvant Therapy for Patients With Stage II/III Colon Cancer.
Samsung Medical Center - Recruiting 18 years or older. - A Prospective Study of Pharmacogenetic Factors and Gene Expression Profile in Patients Receiving Adjuvant Therapy With FOLFOX-6 After Curative Resection of Colon Cancer.
PVS Memorial Hospital - Recruiting 25 years to 75 years. - A Randomised Controlled Trial On Mechanical Bowel Preparation Versus No Mechanical Bowel Preparation In Elective Laparoscopic Surgery For Left Sided Colonic Tumours.
University Hospital, Ghent - Recruiting 18 years to 75 years. - Phase II Study Comparing Normothermic Versus Hyperthermic Intraoperative Chemoperfusion With Oxaliplatin in Patients With Peritoneal Metastases From Appendiceal or Colon Cancer.
University of Utah - Recruiting 18 years to 69 years. - Genetic Events Leading to APC-Dependent Colon Cancer in High-Risk Families; a Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients.
University Hospital Dubrava - Recruiting 20 years to 80 years. - Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer.
Therapeutic conventional colorectal surgery; Therapeutic laparoscopic colorectal surgery; Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
Julius-Maximilians University - Recruiting 19 years to 90 years. - Vaccination of Patients With Advanced Melanoma, Pancreatic, Colon and Cervical Cancer With HLA-A1, -A2 and -B35 Restricted Survivin Peptides.
Hamamatsu University - Recruiting 20 years to 85 years. - Pharmacokinetic and Pharmacodynamic Study of S-1 and Its Effects in Patients With the Digestive Organ Cancer With Reference to Genetic Polymorphism and Activity of CYP2A6 and DPD.