210 results found.

Colorectal Cancer Metastatic Clinical Trial using TheraSphere

BTG International Inc. - Recruiting 18 years or older.
- A Phase III Clinical Trial Evaluating TheraSpherer in Patients With Metastatic Colorectal Carcinoma of the Liver Who Have Failed First Line Chemotherapy.
TheraSphere

Metastatic Colorectal Cancer, Metastatic Gastric Cancer, Metastat Clinical Trial using CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract Cancers.
CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

Colorectal Cancer Metastatic Clinical Trial using AFLIBERCEPT AVE0005; FOLFIRI

Sanofi - Recruiting 18 years or older.
- A Multicenter, Single Arm, Open Label Clinical Trial to Evaluate the Safety and Health-Related Quality of Life of Aflibercept in Patients With Metastatic Colorectal Cancer (mCRC) Previously Treated With an Oxaliplatin-Containing Regimen.
AFLIBERCEPT AVE0005; FOLFIRI

Colorectal Cancer Clinical Trial using panitumumab; erlotinib hydrochloride; irinotecan hydrochloride

Northwestern University - Recruiting 18 years or older.
- A Randomized Phase II Study of Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Irinotecan as Second Line Therapy in Patients With Metastatic Colorectal Cancer.
panitumumab; erlotinib hydrochloride; irinotecan hydrochloride

Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer Clinical Trial using exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE).
exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

Colorectal Cancer Clinical Trial using bevacizumab; FOLFIRI regimen; mFOLFOX6

Genentech - Recruiting 18 years or older.
- A Randomized Phase II Study of Bevacizumab/mFOLFOX6 Versus Bevacizumab/Folfiri With Biomarker Stratification in Patients With Previously Untreated Metastatic Colorectal Cancer.
bevacizumab; FOLFIRI regimen; mFOLFOX6

Colorectal Neoplasms Clinical Trial using Regorafenib (BAY73- 4506)

Bayer - Recruiting 18 years or older.
- An Open-label Phase III Study of Regorafenib in Patients With Metastatic Colorectal Cancer (mCRC) Who Have Progressed After Standard Therapy.
Regorafenib (BAY73- 4506)

Metastatic Colorectal Cancer Clinical Trial using Metastases resection; Bevacizumab; 5 FU (5Fluorouracile); Oxaliplatine; Irinotecan

Cliniques universitaires Saint-Luc- Université Catholique de Louvain - Recruiting 18 years or older.
- Randomized Phase 2 Study Comparing Pathological Responses on Colorectal Cancer Metastases After Preoperative Treatment Combining Bevacizumab With FOLFOX or FOLFIRI.
Metastases resection; Bevacizumab; 5 FU (5Fluorouracile); Oxaliplatine; Irinotecan

Colorectal Cancer, Breast Cancer, Coronary Heart Disease, or Diab Clinical Trial using risk assessment survey; decision support for providers for prevention based on risk

Brigham and Women's Hospital - Recruiting 18 years to 75 years.
- Health Information Technology (HIT) Enhanced Family History Documentation and Management in Primary Care.
risk assessment survey; decision support for providers for prevention based on risk

Metastatic Colorectal Cancer Clinical Trial using Metastases Resection; 5-Fluorouracile; leucovorin L; Oxaliplatin; Irinotecan; Cetuximab

Cliniques universitaires Saint-Luc- Université Catholique de Louvain - Recruiting 18 years or older.
- Randomised Phase 2 Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors.
Metastases Resection; 5-Fluorouracile; leucovorin L; Oxaliplatin; Irinotecan; Cetuximab

Colorectal Neoplasms Clinical Trial using Samples and follow up

Centre Hospitalier Universitaire de NÄ«mes - Recruiting 18 years or older.
- Invasiveness and Chemoresistance of Cancer Stem Cells in Colon Cancer: Molecular Characterization and Implications for Therapeutic Strategies.
Samples and follow up

Solid Tumors, Melanoma, or Metastatic Colorectal Cancer Clinical Trial using CEP-32496

Teva Pharmaceutical Industries - Recruiting 18 years or older.
- An Open-Label, Phase 1/Phase 2, Single-Agent Study of CEP-32496 in Patients With Advanced Solid Tumors in Phase 1 and in Patients With Advanced Melanoma and Metastatic Colorectal Cancer With BRAF Mutation in Phase 2.
CEP-32496

Metastatic Colorectal Cancer Clinical Trial using FOLFOXIRI + Cetuximab; FOLFOXIRI

Sun Yat-sen University - Recruiting 18 years to 75 years.
- A Phase II Study to Evaluate the Surgical Conversion Rate in Patients Receiving FOLFOXIRI +/- Cetuximab for Unresectable Wild-Type KRAS/NRAS Colorectal Cancer With Metastases Confined to the Liver.
FOLFOXIRI + Cetuximab; FOLFOXIRI

Colorectal Cancer Clinical Trial using Korean Red Ginseng; Placebo

Korea Ginseng Corporation - Recruiting 20 years or older.
- A Study of Korean Red Ginseng for Evaluation of Improvement of Cancer-related Fatigue in Patients With Colorectal Cancer With Chemotherapy: A Randomized, Double-blind, Placebo-Controlled, Parallel, Multicenter Trial.
Korean Red Ginseng; Placebo

Cetuximab-induced Papulopustular (Acneiform) Rash Who Have, or Me Clinical Trial using Topical Dapsone 5% Gel; Moisturizer; oral antibiotics

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase III Randomized Double-blind Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT.
Topical Dapsone 5% Gel; Moisturizer; oral antibiotics

Colorectal Cancer Clinical Trial using COLOHYBRITEST OR VALIHYBRITEST

Assistance Publique - H“pitaux de Paris - Recruiting 50 years to 75 years.
- Validation of a Non Invasive methylateDNA Test for te Diagnosis of Colorectal Tumour in Asymptomatic Individuals.
COLOHYBRITEST OR VALIHYBRITEST

Colorectal Cancer Clinical Trial using pharmacodynamic purposes of 89Zr-labelled cetuximab and kinase activity profiles

VU University Medical Center - Recruiting 18 years or older.
- Treatment Optimization of Cetuximab in Patients With Metastatic Colorectal Cancer Based on Tumor Uptake of 89Zr-labeled Cetuximab Assessed by PET.
pharmacodynamic purposes of 89Zr-labelled cetuximab and kinase activity profiles

Colorectal Cancer, Dermatologic Complications, Lung Cancer, or Th Clinical Trial using assessment of therapy complications; psychosocial assessment and care; quality-of-life assessment

Southwest Oncology Group - Recruiting N/A or older.
- S1013: A Prospective Study of Epidermal Growth Factor Receptor (HER-1/EGFR) Inhibitor-Induced Dermatologic Toxicity: Validation of the Functional Assessment of Cancer Therapy-EGFRI 18(FACT-EGFRI 18) Questionnaire for EGFRI-Induced Skin Toxicities.
assessment of therapy complications; psychosocial assessment and care; quality-of-life assessment

Multi-organ Metastatic Colorectal Cancer Clinical Trial using XELOX regimen according to standard procedures; FOLFOX regimen according to standard procedures; Surgery; radiofrequency ablation (RFA); transarterial chemo-embolization using irinotecan drug-eluted beads ((DEBIRI-)TACE); stereotactic body radiation therapy (SBRT); Bevacizumab; tumor biopsy

VU University Medical Center - Recruiting 18 years or older.
- A Randomized Multicenter Clinical Trial for Patient With Multi-organ, Colorectal Cancer Metastases Comparing the Combination of Chemotherapy and Maximal Tumor Debulking Versus Chemotherapy Alone..
XELOX regimen according to standard procedures; FOLFOX regimen according to standard procedures; Surgery; radiofrequency ablation (RFA); transarterial chemo-embolization using irinotecan drug-eluted beads ((DEBIRI-)TACE); stereotactic body radiation therapy (SBRT); Bevacizumab; tumor biopsy

Colorectal Cancer Clinical Trial

Dutch Colorectal Cancer Group - Recruiting 18 years or older.
- The PICNIC Project: a ProspectIve Data CollectioN Initiative on Colorectal Cancer.

Colorectal Cancer, Liver Metastasis, or Colorectal Adenocarcinoma Clinical Trial using Sulindac; Placebo

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Phase 2 Prospective Randomized Double Blind Trial Comparing Metastasectomy Plus Sulindac Versus Metastasectomy Alone in Patients With Stage IV Colorectal Cancer.
Sulindac; Placebo

Lung or Prostatic Neoplasms, Colorectal or Kidney Neoplasms, Panc Clinical Trial using NK cells +CliniMACs CD3 and CD56 systems

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity With Bortezomib.
NK cells +CliniMACs CD3 and CD56 systems

Metastatic Cancer, Metastatic Melanoma, Renal Cancer, Colorectal Clinical Trial using Anti-VEGFR2 CAR CD8 plus PBL; Cyclophosphamide; Aldesleukin; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-VEGFR2 Gene Engineered CD8+ Lymphocytes.
Anti-VEGFR2 CAR CD8 plus PBL; Cyclophosphamide; Aldesleukin; Fludarabine

Colorectal Neoplasms, Gastric Neoplasms, Cholangiocarcinoma, Bile Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- Tumor, Normal Tissue and Specimens From Patients Undergoing Evaluation or Surgical Resection of Solid Tumors.

Colorectal Neoplasms Clinical Trial using folic acid; folic acid calcium vitamin D3; calcium

Shanghai Jiao Tong University School of Medicine - Recruiting 50 years to 80 years.
- A Randomize Controlled Trial of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer.
folic acid; folic acid calcium vitamin D3; calcium

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Observational Study of Avastin Plus 5-FU Based Chemotherapy as First Line Treatment for Chinese Patients With Metastatic Colorectal Cancer..

Colorectal Cancer Clinical Trial using bevacizumab [Avastin]; leucovorin; 5-fluorouracil; irinotecan; oxaliplatin; capecitabine [Xeloda]; fluoropyrimidine-based chemotherapy

Hoffmann-La Roche - Recruiting 18 years to 75 years.
- STEAM (SEQUENTIAL TRIPLET AND AVASTIN MAINTENANCE): FOLFOXIRI/BEVACIZUMAB REGIMENS (CONCURRENT AND SEQUENTIAL) VS. FOLFOX/BEVACIZUMAB IN FIRST-LINE METASTATIC COLORECTAL CANCER.
bevacizumab [Avastin]; leucovorin; 5-fluorouracil; irinotecan; oxaliplatin; capecitabine [Xeloda]; fluoropyrimidine-based chemotherapy

Colorectal Neoplasms Clinical Trial using Regorafenib (Stivarga, BAY73-4506); Placebo

Bayer - Recruiting 18 years or older.
- A Randomized, Double-blind, Placebo-controlled Phase-III Study of Adjuvant Regorafenib Versus Placebo for Patients With Stage IV Colorectal Cancer After Curative Treatment of Liver Metastases.
Regorafenib (Stivarga, BAY73-4506); Placebo

Colorectal Cancer Clinical Trial using Vitamin C; Vitamin B6; Folic acid; Vitamin B6 plus folic acid

Taichung Veterans General Hospital - Recruiting 18 years to 85 years.
- .
Vitamin C; Vitamin B6; Folic acid; Vitamin B6 plus folic acid

Breast Cancer, Colorectal Cancer, Gastric Cancer, Malignant Melan Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- OCCURRENCE RATE OF COLON CANCER, BREAST CANCER, GASTRIC CANCER AND MALIGNANT MELANOMA IN TURKEY & DIAGNOSIS AND TREATMENT CHARACTERISTICS.

Colorectal Cancer, or Adenoma Clinical Trial using Standard Colonoscopy; G-EYE(TM) Colonoscopy

Smart Medical Systems Ltd. - Recruiting 50 years or older.
- G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate - Randomized Tandem Study With Different Endoscopist.
Standard Colonoscopy; G-EYE(TM) Colonoscopy

Colorectal Cancer Clinical Trial using Cancer Symptom Questionnaire; Biomarker Testing

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Assessment of Targeted Therapy Against Colorectal Cancer (ATTACC) Screening Protocol.
Cancer Symptom Questionnaire; Biomarker Testing

Cancer Clinical Trial using Part 1 Cohort 1: Dabrafenib plus Panitumumab; Part 1 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 3A: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 3B: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 4: Dabrafenib plus Trametinib plus Panitumumab; Part 2 Cohort 1: Dabrafenib plus Panitumumab; Part 2 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 3 Cohort 1: Dabrafenib plus Panitumumab; Part 3 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 3 Cohort 3: 5-fluorouracil-based chemotherapy

GlaxoSmithKline - Recruiting 18 years or older.
- An Open-Label, Three-Part, Phase I/II Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of the MEK Inhibitor GSK1120212, BRAF Inhibitor GSK2118436 and the Anti-EGFR Antibody Panitumumab in Combination in Subjects With BRAF-mutation V600E or V600K Positive Colorectal Cancer.
Part 1 Cohort 1: Dabrafenib plus Panitumumab; Part 1 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 3A: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 3B: Dabrafenib plus Trametinib plus Panitumumab; Part 1 Cohort 4: Dabrafenib plus Trametinib plus Panitumumab; Part 2 Cohort 1: Dabrafenib plus Panitumumab; Part 2 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 3 Cohort 1: Dabrafenib plus Panitumumab; Part 3 Cohort 2: Dabrafenib plus Trametinib plus Panitumumab; Part 3 Cohort 3: 5-fluorouracil-based chemotherapy

Colon Cancer Clinical Trial using chemotherapy and GI-4000; GI-4000

Georgetown University - Recruiting 18 years or older.
- A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLOFOX or FOLFIRI in Patients With Newly Diagnosed Ras Mutant Positive Metastatic Colorectal Cancer or Patients With Ras Mutant Positive Colorectal Cancer Who Have Just Completed a First Line Therapy With an Oxaliplatin or Irinotecan Plus Fluoropyrimidine and Bevacizumab Containing Regimen.
chemotherapy and GI-4000; GI-4000

Colorectal Cancer Clinical Trial using PD-0332991, 5-FU, oxaliplatin

Georgetown University - Recruiting 18 years or older.
- A Phase I Study of the CDK4/6 Inhibitor PD-0332991, 5-Fluorouracil, and Oxaliplatin in Patients With Advanced Refractory Colorectal Cancer.
PD-0332991, 5-FU, oxaliplatin

Colorectal Cancer, or Pancreas Cancer Clinical Trial using Dovitinib

Georgetown University - Recruiting 18 years or older.
- A Pilot Study of Dovitinib as Maintenance and Adjuvant Therapy in Patients With Colorectal and Pancreas Cancers.
Dovitinib

Colorectal Cancer Clinical Trial using Early urinary catheter removal

Stanford University - Recruiting 18 years or older.
- Early Removal of Urinary Catheters in Patients After Rectal Surgery: a Prospective Study.
Early urinary catheter removal

Advanced Solid Tumors, Carcinoid, Colorectal Cancer, Locally Adva Clinical Trial using FOLFOX6; Conatumumab; Ganitumab; Bevacizumab

Amgen - Recruiting 18 years or older.
- A Phase 2 Open Label Extension Study of Conatumumab and AMG 479.
FOLFOX6; Conatumumab; Ganitumab; Bevacizumab

Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, or Pai Clinical Trial using Air insufflation method.; Water Immersion method.; Water Exchange method.

Presidio Ospedaliero Santa Barbara - Recruiting 50 years to 70 years.
- A Randomized, Controlled Trial Comparing Air Insufflation, Water Immersion and Water Exchange for Adenoma Detection Rate in Screening Colonoscopy.
Air insufflation method.; Water Immersion method.; Water Exchange method.

Colorectal Cancers Clinical Trial using RENCA macrobeads

The Rogosin Institute - Recruiting 18 years or older.
- A Phase IIb, Nonrandomized, Open-Label Trial With Mouse Renal Adenocarcinoma (RENCA) Cell Containing Agarose-Agarose Macrobeads Compared With Best Supportive Care in Patients With Treatment-Resistant, Metastatic Colorectal Carcinoma.
RENCA macrobeads

Metastatic Colorectal Cancer Clinical Trial using Blood analysis by EPISPOT and Cellsearch

University Hospital, Montpellier - Recruiting 18 years or older.
- Assessment by EPISPOT of Circulating Tumor Cells as an Early Predictive Marker of Response to Chemotherapy and Targeted Therapy in Patients With Metastatic Colorectal Cancer in First Line of Treatment.
Blood analysis by EPISPOT and Cellsearch

Colorectal Cancer Clinical Trial

Chinese University of Hong Kong - Recruiting 18 years or older.
- The Impact of Nursing and Pharmacy Care Between Xelodar and 5-Fluoruracil Regimens in the Management of Colorectal Cancer (CRC) in Hong Kong.

Colorectal Neoplasm Clinical Trial using Regorafenib (Stivarga, BAY 73-4506)

Bayer - Recruiting 18 years or older.
- RECORA- Regorafenib in Patients With Metastatic Colorectal Cancer (mCRC) After Failure of Standard Therapy.
Regorafenib (Stivarga, BAY 73-4506)

Precancerous Condition Clinical Trial using naproxen; placebo; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase Ib Biomarker Trial of Naproxen in Patients at Risk for DNA Mismatch Repair Deficient Colorectal Cancer.
naproxen; placebo; laboratory biomarker analysis

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Non-interventional Study of Avastinr First-line in Metastatic Colorectal Cancer (Koralle).

Metastatic Colorectal Cancer Clinical Trial using Xeloda

Samsung Medical Center - Recruiting 18 years or older.
- A Phase III Trial of XELOX (Xeloda/Oxaliplatin) Followed by Xeloda Maintenance Versus Best Supportive Care (BSC) in Metastatic Colorectal Cancer.
Xeloda

Metastatic Colorectal Cancer Clinical Trial using MEK162; Panitumumab

Novartis - Recruiting 18 years or older.
- A Phase Ib/II, Open-label, Multi-center, Dose Escalation Study of MEK162 in Combination With Panitumumab in Adult Patients With Mutant RAS or Wild-type RAS Metastatic Colorectal Cancer.
MEK162; Panitumumab

Colorectal Neoplasms Clinical Trial using Capecitabine

Sun Yat-sen University - Recruiting 18 years to 80 years.
- Phase II Clinical Trial: Capecitabine Maintenance Therapy in Colorectal Cancer Patients With Stage IIIC and R0-R1 Resected Stage IV.
Capecitabine

Adenomatous Polyp, Colorectal Cancer, or Obesity Clinical Trial using metformin hydrochloride; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 35 years to 80 years.
- A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction Among Patients With a History of Colorectal Adenomas and Elevated Body Mass Index.
metformin hydrochloride; pharmacological study; laboratory biomarker analysis

Metastatic Colorectal Cancer Clinical Trial using Cetuximab; Capecitabine

Swiss Group for Clinical Cancer Research - Recruiting 70 years or older.
- Cetuximab Monotherapy and Cetuximab Plus Capecitabine as First-line Treatment in Elderly Patients With KRAS- and BRAF Wild-type Metastatic Colorectal Cancer. A Multicenter Phase II Trial.
Cetuximab; Capecitabine

Colorectal Cancer Clinical Trial using Folfox plus Bevacizumab and reolysin; Folfox plus Bevacizumab

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Randomized Phase II Study of Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Patients With Metastatic Colorectal Cancer..
Folfox plus Bevacizumab and reolysin; Folfox plus Bevacizumab

Colorectal Cancer Clinical Trial using GS-6624; FOLFIRI; Placebo to match GS-6624

Gilead Sciences - Recruiting 18 years or older.
- A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GS-6624 Combined With FOLFIRI as Second Line Treatment for Metastatic KRAS Mutant Colorectal Adenocarcinoma That Has Progressed Following a First Line Oxaliplatin- and Fluoropyrimidine-Containing Regimen..
GS-6624; FOLFIRI; Placebo to match GS-6624

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- AN OPEN-LABEL, MULTICENTER, NON-INTERVENTION, OBSERVATIONAL STUDY TO ASSESS THE EFFECT OF FIRST LINE BEVACIZUMAB TREATMENT WITH FLUOROPYRIMIDINE-BASED CHEMOTHERAPY (CTX) IN PATIENTS WITH METASTATIC COLORECTAL CANCER.

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Non-interventional Local Study to Describe the Safety, Tolerability and Efficacy of Bevacizumab in Combination With Standard Chemotherapy Regimens as First Line in Patients With Metastatic Cancer of the Colon or the Rectum.

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 75 years or older.
- Non Interventional Study Evaluating Efficacy and Safety in a Cohort of Elderly Patients of First Line Therapy With Avastin r Regimen for Metastatic Colorectal Cancer..

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 70 years or older.
- Prospective Non-interventional Study to Collect Data on the Use of Avastin and Conventional Chemotherapy for the Treatment of Previously Untreated Metastatic Colorectal Cancer in Patients >/= 70 Years.

Colorectal Cancer, Neoplasm Metastasis Clinical Trial using bevacizumab [Avastin]; 5-FU based doublet chemotherapy

Hoffmann-La Roche - Recruiting 18 years to 75 years.
- A Multi-center, Single-arm, Pilot Study of 5-FU Based Doublet Chemotherapy Plus Bevacizumab as Neoadjuvant Therapy for Patients With Previously Untreated Unresectable Liver-only Metastases From Colorectal Cancer.
bevacizumab [Avastin]; 5-FU based doublet chemotherapy

Colorectal Cancer Clinical Trial using Cetuximab; Neratinib

National Surgical Adjuvant Breast and Bowel Project (NSABP) - Recruiting 18 years or older.
- A Phase I/II Dose-Escalation Study Evaluating the Combination of Neratinib and Cetuximab in Patients With 'Quadruple Wild-Type' (KRAS/NRAS/BRAF/PIK3CA Wild-Type) Metastatic Colorectal Cancer Resistant to Cetuximab.
Cetuximab; Neratinib

Colorectal Cancer Clinical Trial

National Surgical Adjuvant Breast and Bowel Project (NSABP) - Recruiting 18 years or older.
- NSABP Patient Registry and Biospecimen Profiling Repository.

Locally Advanced Tumor, Metastatic Solid Tissue Tumors, Liver Can Clinical Trial using DCVax-Direct

Northwest Biotherapeutics - Recruiting 18 years to 75 years.
- A PHASE I/II CLINICAL TRIAL EVALUATING DCVax-Direct, AUTOLOGOUS ACTIVATED DENDRITIC CELLS FOR INTRATUMORAL INJECTION, IN PATIENTS WITH SOLID TUMORS.
DCVax-Direct

Metastatic Colorectal Cancer Clinical Trial using aflibercept + FOLFIRI

CR-CSSS Champlain-Charles-Le Moyne - Recruiting 18 years or older.
- A Phase II Exploratory Study to Identify Biomarkers Predictive of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer Who Have Failed First-Line Therapy.
aflibercept + FOLFIRI

Colorectal Cancer Clinical Trial using RAD011; FOLFOX; Bevacizumab

University of Utah - Recruiting N/A or older.
- A Phase I/II Study of RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma.
RAD011; FOLFOX; Bevacizumab

Colorectal Cancer Metastatic Clinical Trial using aflibercept AVE0005

Sanofi - Recruiting 20 years or older.
- A Single-Arm Phase II Study in Japan to Assess the Efficacy and Safety of Aflibercept Administered Every Two Weeks in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer Who Progressed During or Following an Oxaliplatin-Based Regimen.
aflibercept AVE0005

Colorectal Cancer Metastatic, Liver Metastases, or KRAS Wild Type Clinical Trial using FOLFOX6; Bevacizumab; Panitumumab; Surgery

European Organisation for Research and Treatment of Cancer - EORTC - Recruiting 18 years to 75 years.
- Randomized Phase II Trial Evaluating the Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab as Perioperative Treatment in Patients With Resectable Liver Metastases From Wild Type KRAS Colorectal Cancer.
FOLFOX6; Bevacizumab; Panitumumab; Surgery

Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Clinical Trial using ziv-aflibercept; leucovorin calcium; irinotecan hydrochloride; fluorouracil

City of Hope Medical Center - Recruiting 18 years or older.
- A Prospective Study of Short Infusion of Ziv-Aflibercept in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer.
ziv-aflibercept; leucovorin calcium; irinotecan hydrochloride; fluorouracil

Metastatic Colorectal Cancer, Colon Cancer, or Rectal Cancer Clinical Trial using IMMU-130

Immunomedics, Inc. - Recruiting 18 years or older.
- A Phase I/II Study of Once or Twice Weekly IMMU-130 (hMN-14-SN38, Antibody-Drug Conjugate) in Patients With Colorectal Cancer..
IMMU-130

Colorectal Cancer, or Advanced Colorectal Cancer Clinical Trial using Tumour markers testing

European Organisation for Research and Treatment of Cancer - EORTC - Recruiting 18 years or older.
- Screening Platform of the EORTC for Clinical Trials in Advanced Colorectal Cancer 'SPECTAcolor'.
Tumour markers testing

Colorectal Cancer, or Non-Small Cell Lung Cancer Clinical Trial

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting 18 years or older.
- Correlation of Single Nucleotide Polymorphism (SNP) Profile of Domain III of EGFR to Skin and/or Eye Toxicity and Disease Response to Treatment With Cetuximab or Panitumumab - SNP and Cetuximab or Panitumumab Response.

Breast Cancer, Colorectal Cancer, Lung Cancer, Melanoma (Skin), o Clinical Trial

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting N/A or older.
- Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer.

Prostatic Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Mela Clinical Trial using Interactive Voice Response (IVR) Reminders

Michigan State University - Recruiting 21 years or older.
- Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR.
Interactive Voice Response (IVR) Reminders

Colorectal Cancer Clinical Trial using bevacizumab [Avastin]; XELOX; mFOLFOX6; FOLFIRI

Hoffmann-La Roche - Recruiting 18 years or older.
- An Australian Translational Study to Evaluate the Prognostic Role of Inflammatory Markers in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab (Avastin) [ASCENT].
bevacizumab [Avastin]; XELOX; mFOLFOX6; FOLFIRI

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Program for Assessment of Capecitabine (Xeloda) Based First-line Therapies in Metastatic Colorectal Cancer (AXEL Study).

Colorectal Cancer Clinical Trial using bevacizumab [Avastin]; mFOLFOX6

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multi-center, Open-label Clinical Trial to Evaluate the Objective Response Rate of Bevacizumab in Combination With Modified FOLFOX-6 Followed by One Year of Maintenance With Bevacizumab Alone in Patients With Initially Not or Borderline Resectable Colorectal Liver Metastases (The CLMO-001 Trial).
bevacizumab [Avastin]; mFOLFOX6

Colorectal Cancer Clinical Trial using gene sequencing

Norwegian University of Science and Technology - Recruiting 20 years or older.
- Exom-sekvensering for † Identifisere hoyrisiko Genvarianter i en Familie Predisponert for Colorectal Cancer.
gene sequencing

Colorectal Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Non-interventional Multicenter Study of First-line Avastinr (Bevacizumab) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer.

Hereditary Nonpolyposis Colorectal Cancer, or Colon Cancer Clinical Trial using questionnaires, telephone interview, optional tube of blood drawn; questionnaires, telephone interview and optional tub of blood drawn

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Adherence to Comprehensive, Multi-Organ Screening Recommendations in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients.
questionnaires, telephone interview, optional tube of blood drawn; questionnaires, telephone interview and optional tub of blood drawn

Neoplasms, Neoplasm Metastasis, Melanoma, Carcinoma, Non-Small-Ce Clinical Trial using LY3009120 capsule

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 1 Study of LY3009120 in Patients With Advanced or Metastatic Cancer.
LY3009120 capsule

Colorectal Neoplasms Clinical Trial using Geriatric intervention

Oslo University Hospital - Recruiting 65 years or older.
- Geriatric Intervention in Elderly Surgical Patients With Colorectal Cancer - a Randomized, Controlled Trial..
Geriatric intervention

Colorectal Cancer Metastatic Clinical Trial using Regorafenib (BAY 73-4506); FOLFIRI; Placebo

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- Multi-Center, Randomized, Placebo-Controlled Phase II Study of Regorafenib in Combination With FOLFIRI Versus Placebo With FOLFIRI as Second-Line Therapy in Patients With Metastatic Colorectal Cancer.
Regorafenib (BAY 73-4506); FOLFIRI; Placebo

Patients That Have Been Diagnosed With Cancer, or Patients Eligib Clinical Trial

NovellusDx - Recruiting 18 years to 85 years.
- An Observational Study to Assess the Oncogenic Status of Colorectal Cancer Patients That Have Undergone Surgery.

Pancreatic Cancer, or Colorectal Cancer Clinical Trial using Cancer macrobead placement in abdominal cavity

The Rogosin Institute - Recruiting 18 years or older.
- An Open-Label Phase 2 Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Cell-Containing Agarose-Agarose Macrobeads in the Treatment of Patients With Treatment-Resistant, Metastatic Pancreatic or Colorectal Adenocarcinoma.
Cancer macrobead placement in abdominal cavity

Colorectal Cancer Clinical Trial using Qualitative fecal immunochemical test; Quantitative fecal immunochemical test; Colonoscopy; Cost analysis; Anxiety scores; Patient satisfaction scores

University of Malaya - Recruiting 50 years or older.
- Evaluating the Effectiveness of Screening Strategies Using Quantitative Versus Qualitative Fecal Immunochemical Test (FIT) to Prioritize Urgency of Colonoscopy Referral - a Randomized Controlled Trial Protocol.
Qualitative fecal immunochemical test; Quantitative fecal immunochemical test; Colonoscopy; Cost analysis; Anxiety scores; Patient satisfaction scores

Colorectal Cancer Clinical Trial using Dacomitinib; PD-0325901; Irinotecan; Docetaxel; Capecitabine

The Netherlands Cancer Institute - Recruiting 18 years or older.
- Phase I/II Study With the Combination of Dacomitinib and PD-0325901 in Advanced KRAS Mutation Positive Colorectal, Non-small Cell Lung and Pancreatic Cancer.
Dacomitinib; PD-0325901; Irinotecan; Docetaxel; Capecitabine

Colorectal Cancer Metastatic Clinical Trial using AFLIBERCEPT AVE0005; OXALIPLATIN; CAPECITABINE

Sanofi - Recruiting 18 years or older.
- A Single-Arm, Open Label Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient.
AFLIBERCEPT AVE0005; OXALIPLATIN; CAPECITABINE

Colorectal Neoplasms, Colorectal Carcinoma, or Colorectal Tumors Clinical Trial using ISIS 183750; Irinotecan

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase I/II Study of ISIS 183750 in Combination With Irinotecan in Irinotecan-refractory Colorectal Cancer.
ISIS 183750; Irinotecan

Metastatic Colorectal Cancer, or EGFR-Expressing Metastatic CRC Clinical Trial using Sorafenib (Bay 43-9006); cetuximab; proteomic profiling; immunoenzyme technique; immunohistochemistry staining method; laboratory biomarker analysis; pharmacological study; biopsy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase II Study of BAY 43-9006 (Sorafenib) in Combination With Cetuximab (Erbitux ) in EGFR Expressing Metastatic Colorectal Cancer (CRC).
Sorafenib (Bay 43-9006); cetuximab; proteomic profiling; immunoenzyme technique; immunohistochemistry staining method; laboratory biomarker analysis; pharmacological study; biopsy

Metastatic Colorectal Cancer Clinical Trial using BKM120; Panitumumab

NCIC Clinical Trials Group - Recruiting 18 years or older.
- Phase I/II Study of the P13Kinase Inhibitor BKM120 Given in Combination With Panitumumab in Patients With Metastatic or Advanced RAS-Wild Type Colorectal Cancer..
BKM120; Panitumumab

Colorectal Cancer Clinical Trial using Cetuximab; Bevacizumab; Irinotecan; Oxaliplatin; 5-FU; Folinic Acid

Technische Universit„t Dresden - Recruiting 18 years or older.
- Open, Randomized, Multicenter Phase II Trial With Cetuximab /5-FU/FA/Irinotecan or Cetuximab/5-FU/FA /Irinotecan/Oxaliplatin in K-ras/B-raf Wild Type Patients or With Irinotecan/Oxaliplatin/5-FU/FA With or Without Bevacizumab in K-ras Mutant Patients as Neoadjuvant Treatment in Patients With Non- Resectable Colorectal Liver Metastases..
Cetuximab; Bevacizumab; Irinotecan; Oxaliplatin; 5-FU; Folinic Acid

Stage III Colon Cancer Clinical Trial using AVX701

Duke University - Recruiting 18 years or older.
- A Pilot Study of Active Immunotherapy With CEA(6D) VRP Vaccine (AVX701) in Patients With Stage III Colorectal Cancer.
AVX701

Colorectal Cancer Clinical Trial using Methylene Blue MMXr; Placebo

Cosmo Technologies Ltd - Recruiting 50 years to 75 years.
- The Safety and Efficacy of Methylene Blue MMXr Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy.
Methylene Blue MMXr; Placebo

Colorectal Cancer Clinical Trial using Travasol (amino acid injection); Insulin

McGill University Health Center - Recruiting 18 years or older.
- Enhancing the Anabolic Effect of Perioperative Nutrition With Insulin While Maintaining Normoglycemia.
Travasol (amino acid injection); Insulin

Colorectal Cancer, or Healthy, no Evidence of Disease Clinical Trial using linaclotide acetate; placebo; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years to 65 years.
- Phase I, Randomized, Placebo-Controlled Trial of Linaclotide to Demonstrate Colorectal Bioactivity in Healthy Volunteers.
linaclotide acetate; placebo; pharmacological study; laboratory biomarker analysis

Colorectal Cancer, Dysgeusia, or Oral Complications of Chemothera Clinical Trial using questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; bovine lactoferrin

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study of Bovine Lactoferrin in Patients With Colorectal Carcinoma Receiving Oxaliplatin-Based Chemotherapy and Self-Reported Taste Disturbances.
questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; bovine lactoferrin

Ras-wildtype Colorectal Cancer Clinical Trial using Erythromycin; Doxycycline

AIO-Studien-gGmbH - Recruiting 18 years or older.
- Comparison of Two Preemptive Treatment Strategies of Panitumumab Mediated Skin Toxicity and Assessment of Quality of Life in Patients With Ras-wildtype Colorectal Cancer.
Erythromycin; Doxycycline

Metastatic Colorectal Cancer Clinical Trial using combination panitumumab and vemurafenib

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Pilot Study of Vemurafenib and Panitumumab Combination Therapy in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer.
combination panitumumab and vemurafenib

Colorectal Cancer, or Peritoneal Carcinomatosis Clinical Trial using Indocyanine Green

Jules Bordet Institute - Recruiting 18 years or older.
- Feasibility Study of the (Intravenously Injected) Indocyanine Green (ICG) Imaging of Tumoral Implants in Patients With Peritoneal Carcinomatosis From Colorectal Cancer.
Indocyanine Green

Colorectal Cancer Clinical Trial

Samsung Medical Center - Recruiting 18 years or older.
- .

Colorectal Neoplasms Clinical Trial using BAY73-4506_Regorafenib

Bayer - Recruiting N/A or older.
- Drug Use Investigation of Regorafenib/ STIVARGA for Unresectable, Metastatic or Recurrent Colorectal Cancer.
BAY73-4506_Regorafenib

Solid Tumours of Epithelial Origin, or Metastatic Colorectal Canc Clinical Trial using ColoAd1

PsiOxus Therapeutics Ltd - Recruiting 18 years or older.
- A Clinical Study Of ColoAd1 Administered by Sub-Acute Fractionated Intravenous Injection: Dose Escalation in Metastatic Epithelial Solid Tumours and Randomised Controlled Trial in Metastatic Colorectal Cancer.
ColoAd1

Colorectal Cancer Clinical Trial

Milton S. Hershey Medical Center - Recruiting 18 years or older.
- Prevalence of Stem Cell and Prognostic Markers in Circulating Tumor Cells of Patients With Metastatic Colorectal Cancer Undergoing Chemotherapy.

Metastatic Colorectal Cancer Clinical Trial

National Cancer Institute, Naples - Recruiting 18 years or older.
- Multicentered Observational Prospective Cohort Study on the Treatment of Metastatic Colorectal Cancer and the Role of Evaluating K-Ras.

Colorectal Cancer Clinical Trial using Colonoscopic examination

University Health Network, Toronto - Recruiting 35 years to 49 years.
- Colorectal Cancer Screening in Cancer Survivors Treated With Radiation Therapy.
Colonoscopic examination

Appendix Cancer, or Colorectal Cancer Clinical Trial using Cytoreductive Surgery; HIPEC with Mitomycin-C; EPIC with FUDR and Leucovorin

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- ICARuS (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Single-center, Randomized Phase II Trial of Early Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis.
Cytoreductive Surgery; HIPEC with Mitomycin-C; EPIC with FUDR and Leucovorin

Colorectal Cancer Metastatic Clinical Trial using Sorafenib Plus Capecitabine (SorCape)

University of Florida - Recruiting 18 years or older.
- Sorafenib Plus Capecitabine (SorCape) in Previously Treated Metastatic Colorectal Cancer.
Sorafenib Plus Capecitabine (SorCape)

Colorectal Cancer Clinical Trial using Simvastatin

Samsung Medical Center - Recruiting 20 years or older.
- A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer Patients.
Simvastatin

Peripheral Neuropathy Clinical Trial using Glutamine

Ankara Education and Research Hospital - Recruiting 20 years to 65 years.
- The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy in Colorectal Cancer Patients. Randomized Trial.
Glutamine

Colorectal Neoplasms Clinical Trial using Eflornithine placebo & sulindac placebo; eflornithine & sulindac placebo; Eflornithine placebo & sulindac; Eflornithine plus sulindac

Southwest Oncology Group - Recruiting 18 years or older.
- A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon Cancer, Phase III - Preventing Adenomas of the Colon With Eflornithine and Sulindac (PACES).
Eflornithine placebo & sulindac placebo; eflornithine & sulindac placebo; Eflornithine placebo & sulindac; Eflornithine plus sulindac

Colorectal Cancer, or Metastatic Cancer Clinical Trial using floxuridine; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Multi-Institutional Efficacy and Safety Study of Chemotherapy With Selective Internal Radiation Treatment Using Y-90 Microspheres (CHEMO-SIRT) in Patients With Colorectal Cancer Liver Metastasis.
floxuridine; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

Metastatic Breast Cancer, Colorectal Cancer, or Prostate Cancer Clinical Trial using Foxy-5

WntResearch AB - Recruiting 18 years or older.
- Phase I Dose Escalating Study to Evaluate the Safety, Tolerability, Anti-Tumour Activity and Pharmacokinetic and Pharmacodynamic Profiles of Foxy-5 in Patients With Metastatic Breast, Colorectal or Prostate Cancer.
Foxy-5

Colorectal Cancer Clinical Trial using medical chart review; survey administration; fecal occult blood test; screening colonoscopy

National Cancer Institute (NCI) - Recruiting 50 years to 74 years.
- Tailored Navigation in CRC Screening.
medical chart review; survey administration; fecal occult blood test; screening colonoscopy

Colorectal Cancer Clinical Trial using informational intervention; medical chart review; screening questionnaire administration; study of socioeconomic and demographic variables; barium enema injection; colon imaging study; screening colonoscopy; sigmoidoscopy

National Cancer Institute (NCI) - Recruiting 50 years to 79 years.
- Increasing Colon Cancer Screening in Primary Care Among African Americans.
informational intervention; medical chart review; screening questionnaire administration; study of socioeconomic and demographic variables; barium enema injection; colon imaging study; screening colonoscopy; sigmoidoscopy

Carcinoma Clinical Trial

Onkovis GmbH - Recruiting N/A or older.
- Open, Multicenter Observational Study of Oxaliplatin Utilized in Combination Therapy for Adjuvant Treatment of Colon Carcinoma of Stage III After Complete Removal of the Primary Tumor and for Treatment of Metastasizing Colorectal Carcinoma..

Colorectal Cancer Clinical Trial

National University Hospital, Singapore - Recruiting 21 years or older.
- .

Colorectal Cancer Clinical Trial using Telephone Interview; Questionnaire

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Cancer Survivorship in Lynch Syndrome: Impact on Patients and Families.
Telephone Interview; Questionnaire

Colorectal Cancer Clinical Trial using 5 cm colon-J-pouch; side-to-end anastomosis; straight coloanal anastomosis

Swiss Group for Clinical Cancer Research - Recruiting 18 years or older.
- Clinical Function After Total Mesorectal Excision and Rectal Replacement. A Prospective Randomized Trial Comparing Side-to-End Anastomosis, Colon-J-Pouch and Straight Coloanal Anastomosis.
5 cm colon-J-pouch; side-to-end anastomosis; straight coloanal anastomosis

Adenomatous Polyp Clinical Trial using eflornithine; acetylsalicylic acid; placebo; laboratory biomarker analysis; telephone-based intervention

National Cancer Institute (NCI) - Recruiting 40 years or older.
- Randomized Phase II Trial of Aspirin and Difluoromethylornithine (DFMO) in Patients at High Risk of Colorectal Cancer.
eflornithine; acetylsalicylic acid; placebo; laboratory biomarker analysis; telephone-based intervention

Colorectal Cancer Clinical Trial using Progressive Group

St. Michael's Hospital, Toronto - Recruiting N/A or older.
- Do Progressive Levels of Simulation Fidelity Enhance Colonoscopic Skill Acquisition and Transfer in Novice Endoscopic Trainees?.
Progressive Group

Colorectal Cancer Clinical Trial using two stage hepatectomy

Centre Hospitalier Universitaire, Amiens - Recruiting 18 years or older.
- Associating Liver Partition and Portal Vein Ligation (ALPPS) for Potentially Resectable Liver Metastasis From Colorectal Cancer: Prospective Evaluation of the Early Two-stage Hepatectomy by the Simon's Methods.
two stage hepatectomy

Colorectal Cancer Clinical Trial using Exercise Program; Telephone-based intervention; Counseling intervention; Questionnaire administration; Relaxation Program

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Comparative Study of Oncologist Recommended, Home-Based Exercise Program and Relaxation Training for Physical Functioning and Symptom Control in Colon Cancer Patients.
Exercise Program; Telephone-based intervention; Counseling intervention; Questionnaire administration; Relaxation Program

Colorectal Cancer Clinical Trial using NKTR-102; irinotecan

Nektar Therapeutics - Recruiting 18 years or older.
- A Multicenter, Open-Label, Randomized, Phase 2 Study to Evaluate the Efficacy and Safety of NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naive, KRAS-Mutant, Metastatic Colorectal Cancer (mCRC).
NKTR-102; irinotecan

Major Advanced Solid Tumors Other Than Colorectal Clinical Trial using PM01183

PharmaMar - Recruiting 18 years or older.
- Phase I Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM01183 on Days 1 and 8 Every Three Weeks (q3wk) in Non-Colorectal Cancer (Non-CRC) Patients.
PM01183

Total Exenteration,, Anterior or Posterior Pelvic Exenteration, G Clinical Trial using questionnaires/interviews

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Prospective Study of Quality of Life in Patients Undergoing Pelvic Exenteration.
questionnaires/interviews

Metastatic Colorectal Cancer Clinical Trial using Aflibercept

Brown University - Recruiting 18 years or older.
- BrUOG C261:Single Agent Adjuvant Aflibercept for Patients With Resected or Ablated Metastatic Colorectal Cancer: A Randomized Phase II Study.
Aflibercept

Colorectal Cancer, or Head and Neck Cancer Clinical Trial using Doxycycline; Hydrocortisone 1% cream; Sunscreen; Moisturizer; Clindamycin; Medrol-dose pack (Steroid)

James Graham Brown Cancer Center - Recruiting 18 years or older.
- Preemptive Therapy Study of Cetuximab(Erbituxr)Induced Skin Rash Using Doxycycline, Sunscreen, Hydrocortisone and Moisturizer in Colorectal and Head and Neck Cancer Patients.
Doxycycline; Hydrocortisone 1% cream; Sunscreen; Moisturizer; Clindamycin; Medrol-dose pack (Steroid)

Colorectal Cancer Screening Clinical Trial using MyCRCS+Prefs; MyCRCS+Prefs+Barriers

Virginia Commonwealth University - Recruiting 50 years to 75 years.
- An Interactive Preventive Health Record to Increase Colorectal Cancer Screening.
MyCRCS+Prefs; MyCRCS+Prefs+Barriers

Colorectal Cancer Clinical Trial using Questionnaire

M.D. Anderson Cancer Center - Recruiting N/A to 60 years.
- Screening and Risk Communication for First Degree Relatives of Colorectal Cancer Patients.
Questionnaire

Colorectal Cancer Metastatic Clinical Trial using Aflibercept AVE0005; Placebo

Sanofi - Recruiting 18 years or older.
- A Multinational, Randomized, Double-Blind Study of Aflibercept Versus Placebo With Irinotecan/ 5-FU Combination (FOLFIRI) in Patients With Metastatic Colorectal Cancer (MCRC) After Failure of an Oxaliplatin Based Regimen.
Aflibercept AVE0005; Placebo

Colorectal Neoplasms Clinical Trial using Nadroparin; Placebo

Fudan University - Recruiting 18 years to 80 years.
- Study of The Effect of Low Molecular Weight Heparin on Survival in Patients With Advanced Colorectal Cancer.
Nadroparin; Placebo

Colorectal Cancer, or Head and Neck Cancer Clinical Trial using Nilotinib + Cetuximab

Georgetown University - Recruiting 18 years or older.
- A Phase I Study of the BCR-ABL Tyrosine Kinase Inhibitor Nilontinib and Cetuximab in Patients With Solid Tumors That Can be Treated With Cetuximab.
Nilotinib + Cetuximab

Colorectal Cancer Clinical Trial using LGX818; Cetuximab; BYL719

Novartis - Recruiting 18 years or older.
- A Phase lb/II Multi-center, Open-label, Dose Escalation Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in Patients With BRAF Mutant Metastatic Colorectal Cancer.
LGX818; Cetuximab; BYL719

Colorectal Cancer Clinical Trial using Rehabilitation program

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Benefit of Rehabilitation Program in Colorectal Laparoscopic Surgery.
Rehabilitation program

First Recently-diagnosed Colorectal Cancer Clinical Trial using Blood sample; tissue samples from abdominal subcutaneous adipose

Centre Hospitalier Universitaire Dijon - Recruiting 45 years or older.
- Consumption of Fatty Acids, Metabolism of Adipose Tissue and Risk of Colorectal Cancer: AGARIC Case Control Study.
Blood sample; tissue samples from abdominal subcutaneous adipose

Colorectal Cancer Clinical Trial using Surgical resection of recurrent colorectal cancer; Chemokine-modulatory (CKM) regimen

University of Pittsburgh - Recruiting 18 years or older.
- Randomized Phase I/II Evaluation of Neoadjuvant Administration of a Chemokine-Modulatory Regimen in Patients With Recurrent Resectable Colorectal Cancer.
Surgical resection of recurrent colorectal cancer; Chemokine-modulatory (CKM) regimen

Breast Cancer, Prostate Cancer, or Colorectal Cancer Clinical Trial

Viatar LLC - Recruiting 18 years or older.
- Collection of Blood Specimens for Circulating Tumor Cell Analysis.

MSI Positive Colorectal Cancer, MSI Negative Colorectal Cancer, o Clinical Trial using MK-3475

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors.
MK-3475

Colorectal Cancer Clinical Trial using FDG PET-CT; Diffusion MRI; Blood samples (plasma preparation and CTC)

Jules Bordet Institute - Recruiting 18 years or older.
- Correlating the Tumoral Metabolic Progression Index Measured by Serial FDG PET-CT and Apparent Diffusion Coefficient Measured by MRI to Patient's Outcome in Advanced Colorectal Cancer.
FDG PET-CT; Diffusion MRI; Blood samples (plasma preparation and CTC)

Colorectal Neoplasms, or Metastatic Disease Clinical Trial using Regorafenib

Spanish Cooperative Group for Digestive Tumour Therapy (TTD) - Recruiting 18 years or older.
- A Phase II Study of Single-agent Regorafenib in the First Line Treatment of Frail and/or Unfit for Polychemotherapy Patients With Metastatic Colorectal Cancer (mCRC).
Regorafenib

Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of Clinical Trial using panitumumab; irinotecan hydrochloride; fluorouracil; leucovorin calcium

Ohio State University Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Panitumumab in Combination With FOLFIRI After Progression on FOLFIRI Plus Bevacizumab in KRAS(Kirsten Rat Sarcoma) Wild-Type Metastatic Colorectal Cancer..
panitumumab; irinotecan hydrochloride; fluorouracil; leucovorin calcium

Carcinoma Clinical Trial

Onkovis GmbH - Recruiting N/A or older.
- Open, Multicenter Observational Study of Irinotecan Utilized in Mono- or Combination Therapy for the Treatment of Advanced Colorectal Carcinoma..

Metastatic Colorectal Cancer Clinical Trial using FOLFOXIRI + Panitumumab; FOLFOXIRI

AIO-Studien-gGmbH - Recruiting 18 years or older.
- An Open-label 2:1 Randomized Phase II Study of Panitumumab Plus FOLFOXIRI or FOLFOXIRI Alone as First-line Treatment of Patients With Non-resectable Metastatic Colorectal Cancer and K-ras Wild Type.
FOLFOXIRI + Panitumumab; FOLFOXIRI

Colorectal Cancer Clinical Trial using EndoVe endoscopic electroporation

Mercy University Hospital, Cork, Ireland - Recruiting 18 years or older.
- Treatment of Inoperable Colorectal Cancer With Electrochemotherapy Through an Endoscopic System.
EndoVe endoscopic electroporation

Breast Cancer, Pancreatic Cancer, Colorectal Cancer, Non-small-ce Clinical Trial using MORAb-066

Morphotek - Recruiting 18 years or older.
- A Phase I Study of the Safety, Tolerability, and PK of MORAb-066, a Humanized Monoclonal Antibody to Human TF, in Patients With Advanced or Metastatic Breast, Pancreatic, Colorectal, or NSCLC (Adenocarcinoma) Malignancies.
MORAb-066

Colorectal Cancer Clinical Trial using panitumumab; cyclosporine; irinotecan hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomised Clinical Trial of Treatment for Fluorouracil-Resistant Advanced Colorectal Cancer Comparing Standard Single-Agent Irinotecan Versus Irinotecan Plus Panitumumab and Versus Irinotecan Plus Ciclosporin [Panitumumab, Irinotecan & Ciclosporin in COLOrectal Cancer Therapy (PICCOLO)].
panitumumab; cyclosporine; irinotecan hydrochloride

Breast Cancer, Colorectal Cancer, Esophageal Cancer, Head and Nec Clinical Trial using 18F-fluoromisonidazole; fluorescence angiography; laboratory biomarker analysis; infrared thermography; magnetic resonance imaging; therapeutic conventional surgery; [18F]-ML-10; fludeoxyglucose F 18; rubidium Rb-82

National Cancer Institute (NCI) - Recruiting N/A or older.
- Tumor Angiogenesis in Non-Small Cell Lung (NSCLC), Colorectal, Breast, Esophageal, Head and Neck Cancer: Radiology-Pathology and Prognostic Correlation.
18F-fluoromisonidazole; fluorescence angiography; laboratory biomarker analysis; infrared thermography; magnetic resonance imaging; therapeutic conventional surgery; [18F]-ML-10; fludeoxyglucose F 18; rubidium Rb-82

Colorectal Cancer Clinical Trial using polymorphism analysis; laboratory biomarker analysis; questionnaire administration

National Cancer Institute (NCI) - Recruiting 18 years to 69 years.
- A Population Based Study of Genetic Predisposition and Gene-Environment Interactions in Colorectal Cancer in East Anglia.
polymorphism analysis; laboratory biomarker analysis; questionnaire administration

Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of Clinical Trial using Akt inhibitor MK2206; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 2 Study of MK-2206 in Previously Treated Metastatic Colorectal Cancer Patients Enriched for PTEN Loss and PIK3CA Mutation.
Akt inhibitor MK2206; laboratory biomarker analysis; pharmacological study

Metastatic Pancreatic Cancer, or Metastatic Colorectal Cancer Clinical Trial using NPC-1C/NEO-102

Precision Biologics, Inc - Recruiting 18 years to 85 years.
- A Phase 1/2A Therapeutic, Open Label, Multi-Center Clinical Trial of NPC-1C, a Chimeric Monoclonal Antibody, in Adults With Recurrent, Locally Advanced Unresectable or Metastatic Pancreatic and Colorectal Cancer After Standard Therapy.
NPC-1C/NEO-102

Pancreatic Adenocarcinoma, or Colorectal Cancer Clinical Trial

Oslo University Hospital - Recruiting N/A or older.
- The Process of Metastasis in Colorectal Cancer Tumour Biology and Prognostic Factors in Pancreatic Cancer.

Metastatic Colorectal Cancer Patients Clinical Trial using Gemcitabine + Pemetrexed

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori - Recruiting 18 years or older.
- A Phase II Study to Evaluate Activity and Toxicity of Gemcitabine in Combination With Pemetrexed Long Term Infusion in the Treatment of Pretreated Metastatic Colorectal Cancer Patients.
Gemcitabine + Pemetrexed

Colorectal Cancer Clinical Trial using OCV-103 and OCV-104

Otsuka Pharmaceutical Co., Ltd. - Recruiting 20 years or older.
- A Phase 1 Study of OCV-C02 in Patients With Advanced or Relapsed Colorectal Cancer Who Are Refractory or Intolerant to Standard Chemotherapy.
OCV-103 and OCV-104

Colorectal Cancer Clinical Trial using Xenon; Desflurane

Centre Leon Berard - Recruiting 18 years or older.
- Phase II Study, Randomized, Monocentric, Single-blind, Comparing the Efficacy of Gases Xenon and Desflurane , in Association With a Thoracic Epidural Analgesia in Maintenance Phase of a Colorectal Oncologic Surgery.
Xenon; Desflurane

Stage IV Colorectal Cancer Clinical Trial using Vitamin C

Thomas Jefferson University - Recruiting 18 years or older.
- Phase I/II Study of Intravenous Ascorbic Acid in Combination With Irinotecan Versus Irinotecan Alone for Advanced Colorectal Cancer.
Vitamin C

Colorectal Cancer, or Breast Cancer Clinical Trial using Exercise training; Exercise training plus metformin; Metformin; Educational information

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- Randomized Phase II Study of Exercise and Metformin in Colorectal and Breast Cancer Survivors.
Exercise training; Exercise training plus metformin; Metformin; Educational information

Colorectal Cancer Clinical Trial using capecitabine; 5-fluorouracil; Surgical Resection; Radiation therapy

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- A Biologic Study of Global Gene Expression, NF-Kappa B and p53 in Adenocarcinoma of the Rectum..
capecitabine; 5-fluorouracil; Surgical Resection; Radiation therapy

Colorectal Cancer, or Metastasis Clinical Trial using Bevacizumab + blood samples

Centre Leon Berard - Recruiting 18 years or older.
- Exploration of New Biologic Factors' Predictive Value , Especially Circulating VE-cadherin in Metastatic Colorectal Adenocarcinoma Patients Treated With Bevacizumab.
Bevacizumab + blood samples

Rectal Cancer, Colon Cancer, Metastasis, or Adenocarcinoma Clinical Trial using Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Phase I/II Pharmacodynamic Study of Hydroxychloroquine in Combination With FOLFOX Plus Bevacizumab to Inhibit Autophagy in Colorectal Cancer.
Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Rectal Cancer, or Colon Cancer Clinical Trial using polyethylene glycol; No Preparation

PVS Memorial Hospital - Recruiting 25 years to 75 years.
- A Randomised Controlled Trial On Mechanical Bowel Preparation Versus No Mechanical Bowel Preparation In Elective Laparoscopic Surgery For Left Sided Colonic Tumours.
polyethylene glycol; No Preparation

Metastatic Colorectal Cancer Clinical Trial using fluorouracil/irinotecan/levo-folinic acid/bevacizumab

University of Rome Tor Vergata - Recruiting N/A or older.
- Observational Study of the Impact of Circulating T Regulatory Cells (Tregs) on Clinical Outcome of Metastatic Colorectal Cancer (MCRC) Patients Treated With Standard Fluorouracil/Irinotecan/Bevacizumab First Line Therapy.
fluorouracil/irinotecan/levo-folinic acid/bevacizumab

Colorectal Cancer Clinical Trial using Aspirin

University of California, Irvine - Recruiting 18 years to 80 years.
- Phase IIA Clinical Biomarker Trial of Aspirin and Arginine Restriction in Colorectal Cancer Patients.
Aspirin

Colorectal and Ovarian Cancer Patients With Liver Metastasis Clinical Trial using EMD525797

Merck KGaA - Recruiting 18 years or older.
- A Phase I, Open-label, Dose-escalation Study to Investigate the Safety, Tolerability, PD and PK of EMD 525797 Using DCE-MRI as a PK Measure of Response in Colorectal and Ovarian Cancer Patients With Liver Metastases After Failure of Standard Therapy.
EMD525797

Breast Cancer, Non-small Cell Lung Cancer, Colorectal Cancer, Gen Clinical Trial

University Health Network, Toronto - Recruiting 18 years or older.
- Integrated Molecular Profiling in Advanced Cancers Trial.

Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors Clinical Trial using Sorafenib and irinotecan combination; Sorafenib monotherapy; Irinotecan monotherapy

Centre Val d'Aurelle - Paul Lamarque - Recruiting 18 years or older.
- A Randomized Phase II Trial Assessing Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors After Failure of All Drugs Known to be Effective.
Sorafenib and irinotecan combination; Sorafenib monotherapy; Irinotecan monotherapy

Colorectal Neoplasms, Neoplasm Metastasis, or Liver Neoplasms Clinical Trial using Cetuximab; chemotherapy of mFOLFOX6 or FOLFIRI

Fudan University - Recruiting 18 years to 75 years.
- Study of Cetuximab in Combination With Chemotherapy for the First Treatment of Metastatic Colorectal Cancer.
Cetuximab; chemotherapy of mFOLFOX6 or FOLFIRI

Colorectal Cancer Clinical Trial

Diskapi Teaching and Research Hospital - Recruiting N/A or older.
- Cohort Study on Patients Underwent Colorectal Surgery.

Metastatic Colorectal Cancer Clinical Trial

Institut National de la Sant‚ Et de la Recherche M‚dicale, France - Recruiting 18 years or older.
- Molecularly Imprinted Polymer Sensors of Modified Nucleosides for Non-invasive Monitoring of Cancer Therapy : Effect of Chemotherapy on Cancerous Proliferation Based on the Dynamic Excretion of Urinary Nucleosides..

Colorectal Cancer Clinical Trial using mechanical bowel preparation; enema

European Institute of Oncology - Recruiting 18 years to 80 years.
- Effect of Mechanical Bowel Preparation With Polyethylene Glycol Plus Bowel Enema (Glycerine 5%) vs Bowel Enema Alone in Patients Candidates to Colorectal Resection for Malignancy. Prospective, Randomized Clinical Trial.
mechanical bowel preparation; enema

Metastatic Colorectal Cancer Clinical Trial using Perfusion CT scan

University of Oxford - Recruiting 18 years or older.
- Perfusion Computed Tomography Pilot Study in the NCRN FOXFIRE Clinical Trial to Determine Blood Flow to Liver Metastases.
Perfusion CT scan

Colorectal Cancer, Breast Cancer, or Cervical Cancer Clinical Trial using Coach Intervention (COACH)

Johns Hopkins Bloomberg School of Public Health - Recruiting 65 years to 74 years.
- Evaluating Coaches for Older Adults Cancer Care and Health.
Coach Intervention (COACH)

Colorectal Cancer Clinical Trial using capecitabine; fluorouracil; oxaliplatin

Cancer Research UK, Glasgow - Recruiting 18 years or older.
- Short Course Oncology Therapy - A Study of Adjuvant Chemotherapy in Colorectal Cancer.
capecitabine; fluorouracil; oxaliplatin

Colorectal Cancer With Liver Metastasis Clinical Trial using perihepatic lymphadenectomy

Gachon University Gil Medical Center - Recruiting 18 years to 80 years.
- Prospective Phase II Trial on Prophylactic Perihepatic Lymphadenectomy in Patients With Colorectal Cancer With Liver Metastasis.
perihepatic lymphadenectomy

Colorectal Cancer Screening Clinical Trial using Patient Navigation

Institut National de la Sant‚ Et de la Recherche M‚dicale, France - Recruiting 50 years to 74 years.
- The Patient Navigator to Reduce Social Inequalities. A French Interventional Trial in Public Health.
Patient Navigation

Colorectal Cancer, Pain, or Other Complications Clinical Trial using Ropivacaine + opioid epidurally; Morphine

™rebro University, Sweden - Recruiting 40 years to 80 years.
- Epidural or Patient-controlled Analgesia for Colorectal Cancer Surgery. Long-term Outcomes..
Ropivacaine + opioid epidurally; Morphine

Metastatic Colorectal Cancer Clinical Trial using Capecitabine; Bevacizumab; Irinotecan

University Hospital of Crete - Recruiting 18 years to 72 years.
- A Phase II Study of Irinotecan, Capecitabine and Avastin in Patients With Metastatic Colorectal Cancer, Who Have Progressed After 1ST Line Therapy With Folfox/Avastin..
Capecitabine; Bevacizumab; Irinotecan

Metastatic Colorectal Cancer Clinical Trial using Biomarker sampling

Helsinki University Central Hospital - Recruiting 18 years or older.
- A Population-based Prospective Study to Evaluate Clinical Behaviour, Resectability and Survival in 1st Line Metastatic Colorectal Cancer (CRC) Patients in Finland.
Biomarker sampling

Hepatocellular Cancer, Non-small Cell Lung Cancer, Renal Cell Can Clinical Trial using Avastin; Suntent; Nexavar

Medical University Innsbruck - Recruiting 18 years or older.
- Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients.
Avastin; Suntent; Nexavar

Metastatic Colorectal Cancer Clinical Trial using Capecitabine (Xeloda), Oxaliplatin, Irinotecan, Bevacizumab

King Faisal Specialist Hospital & Research Center - Recruiting 14 years to 85 years.
- A Phase I-II Trial of Capecitabine (Xeloda), Oxaliplatin and Irinotecan in Combination With Bevacizumab in 1st Line Treatment of Metastatic Colorectal Cancer.
Capecitabine (Xeloda), Oxaliplatin, Irinotecan, Bevacizumab

Colorectal Carcinoma Clinical Trial using axitinib

Gustave Roussy, Cancer Campus, Grand Paris - Recruiting 18 years or older.
- Assessment of the Tumor Vascular Effects of the Pan-vegfr Tyrosine Kinase Inhibitor Axitinib Using Dynamic Contrast-enhanced Ultrasonography (Dce-us) in Patients With Refractory Metastatic Colorectal Cancer.
axitinib

Colorectal Cancer Clinical Trial using curative resection for colorectal cancer; intra-operative 5-FU chemotherapy

Sun Yat-sen University - Recruiting 18 years to 75 years.
- A Prospective,Single-center,Randomized,Controlled Phase III Clinical Study Comparing Efficacy and Safety of Intraoperative Chemotherapy With 5-Fluorouracil Plus Curative Resection Versus Surgery Alone for Patients With Colorectal Cancer.
curative resection for colorectal cancer; intra-operative 5-FU chemotherapy

Inflammatory Bowel Disease, or Colorectal Cancer Clinical Trial

UMC Utrecht - Recruiting 18 years to 70 years.
- Risk Factors for Colorectal Cancer in Patients With Inflammatory Bowel Disease Undergoing Surveillance: a Prospective Cohort Study.

Colorectal Cancer Clinical Trial using Multi-modality imaging

Radboud University - Recruiting 18 years or older.
- Multi-modality Imaging in the Prediction of Response to Systemic Treatment in Colorectal Cancer.
Multi-modality imaging

Colorectal Cancer Clinical Trial

University of Puerto Rico - Recruiting 15 years or older.
- Familial Colorectal Cancer In Puerto Rico: A Feasibility Study.

Colorectal Cancer Clinical Trial using laboratory biomarker analysis; computed tomography; magnetic resonance imaging; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 50 years or older.
- A Randomised Controlled Trial to Assess the Cost-effectiveness of Intensive Versus no Scheduled Follow-up in Patients Who Have Undergone Resection for Colorectal Cancer With Curative Intent. (FACS - Follow-up After Colorectal Surgery).
laboratory biomarker analysis; computed tomography; magnetic resonance imaging; quality-of-life assessment

Colorectal Cancer Clinical Trial using loss of heterozygosity analysis; microsatellite instability analysis; mutation analysis; counseling intervention

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Outcomes in Education and Counseling for HNPCC Testing.
loss of heterozygosity analysis; microsatellite instability analysis; mutation analysis; counseling intervention

Colorectal Cancer Clinical Trial using bevacizumab; capecitabine; fluorouracil; irinotecan hydrochloride; diagnostic laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years to 80 years.
- Phase II Study Evaluating the Association of Bevacizumab and Chemotherapy of the Type Modified FOLFIRI 3 in Patients With Metastatic Colorectal Adenocarcinoma.
bevacizumab; capecitabine; fluorouracil; irinotecan hydrochloride; diagnostic laboratory biomarker analysis

Colorectal Cancer Clinical Trial using cetuximab; irinotecan hydrochloride; conventional surgery; neoadjuvant therapy; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years to 74 years.
- Neoadjuvant Conformal Radiotherapy and Concomitant CPT-11 and EGFR Inhibition With Cetuximab in Patients With Rectal Cancer Phase I Study.
cetuximab; irinotecan hydrochloride; conventional surgery; neoadjuvant therapy; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

Colorectal Cancer, or Primary Peritoneal Cavity Cancer Clinical Trial using fluorouracil; leucovorin calcium; oxaliplatin; hyperthermia treatment

National Cancer Institute (NCI) - Recruiting 18 years to 70 years.
- Phase III Study Evaluating the Use of Systemic Chemotherapy and Chemohyperthemia Intraperitoneal Preoperatively (CHIP) and After Maximum Resection of Peritoneal Carcinomatosis Originating With Colorectal Cancer.
fluorouracil; leucovorin calcium; oxaliplatin; hyperthermia treatment

Colorectal Cancer Clinical Trial using SB injection

SBPharmaceutical IND, Co., LTD - Recruiting 18 years or older.
- Phase ?,Open Label Clinical Trial to Investigate Safety and Efficacy of SB Injection in Patients With Advanced and Metastatic Colorectal Cancer.
SB injection

Colorectal Cancer Clinical Trial using Co-signed Letter; Control

University of Paris 5 - Rene Descartes - Recruiting 50 years to 74 years.
- Does the Invitation by the General Practitioner Improve Patients' Participation in Colorectal Cancer Screening? A Cluster Randomised Controlled Study..
Co-signed Letter; Control

Metastatic Colorectal Cancer Clinical Trial using AMG386 and bevacizumab

Austin Health - Recruiting N/A or older.
- Open Label Phase II Study Evaluating the Combination of Bevacizumab and AMG386 Without Chemotherapy as First Line Treatment of Advanced Colorectal Cancer.
AMG386 and bevacizumab

Colorectal Cancer Clinical Trial using FOLFIRI regimen; fluorouracil; irinotecan hydrochloride; leucovorin calcium; zibotentan; laboratory biomarker analysis; pharmacogenomic studies

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase II Study of Irinotecan, 5-Fluorouracil and Folinic Acid (FOLFIRI) With or Without the Addition of an Endothelin Receptor Antagonist in Patients With Metastatic Colorectal Cancer After Failure of Oxaliplatin-Containing Chemotherapy.
FOLFIRI regimen; fluorouracil; irinotecan hydrochloride; leucovorin calcium; zibotentan; laboratory biomarker analysis; pharmacogenomic studies

Colorectal Neoplasms Clinical Trial using sorafenib; FOLFIRI

Fudan University - Recruiting 18 years to 75 years.
- A Phase ? Open Label, Non Randomized Study, in Which Sorafenib is Used in Combination With Irinotecan, Leucovorin and Fluorouracil in Patients With Advanced Colorectal Cancer After Failure of Oxaliplatin Treatment.
sorafenib; FOLFIRI

Colorectal Cancer Clinical Trial using 5-fluorouracil and Capecitabine

State Key Laboratory of Cancer Biology - Recruiting 18 years to 90 years.
- Clinical Trial on Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III Among Chinese Population.
5-fluorouracil and Capecitabine

Colorectal Cancer Clinical Trial using S-1, leucovorin, oxaliplatin

Peking University - Recruiting 20 years to 80 years.
- A Multicenter Feasibility Study With S-1, Oxaliplatin and Oral Leucovorin (SOL) for the Patients With Untreated Metastatic Colorectal Cancer.
S-1, leucovorin, oxaliplatin

Colorectal Cancer Screening Clinical Trial using multilingual navigator

Massachusetts General Hospital - Recruiting 52 years to 79 years.
- Improving Colorectal Cancer Screening Rates by Lowering Barriers in Low Income and Non-English Speaking Populations: The Chelsea Colorectal Cancer Screening Project.
multilingual navigator

Rectal Cancer Clinical Trial using Short course of radiotherapy; Radiochemotherapy

Polish Colorectal Cancer Study Group - Recruiting 18 years or older.
- The Randomised Study of Preoperative Radiotherapy and Local Excision for Radiosensitive Rectal Cancer.
Short course of radiotherapy; Radiochemotherapy

Rectal Cancer Clinical Trial using Short course of radiotherapy; Radiochemotherapy

Polish Colorectal Cancer Study Group - Recruiting 18 years to 75 years.
- Short-course Preoperative Radiotherapy With Consolidating Chemotherapy vs. Preoperative Chemoradiation in Patients With Unresectable Rectal Cancer: Phase III Study.
Short course of radiotherapy; Radiochemotherapy

Colonic Neoplasms Clinical Trial using Therapeutic conventional colorectal surgery; Therapeutic laparoscopic colorectal surgery; Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest

University Hospital Dubrava - Recruiting 20 years to 80 years.
- Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer.
Therapeutic conventional colorectal surgery; Therapeutic laparoscopic colorectal surgery; Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest

Advanced Colorectal Cancer Clinical Trial using Nimotuzumab and chemotherapy

Peking University - Recruiting 18 years or older.
- Phase IIa Study of Nimotuzumab Plus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer With Wild Type K-ras.
Nimotuzumab and chemotherapy

Colorectal Cancer Clinical Trial

Hamamatsu University - Recruiting 18 years or older.
- Comparative Study of Fecal RNA Test With Immunochemical Fecal Occult Blood Test for Detecting Colorectal Cancer and Adenoma.

Colorectal Cancer Clinical Trial using FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Open- Labeled, Prospective Study to Determine the Efficacy of Pre- Operative Chemotherapy With Six Cycles of Modified FOLFOX 6 Followed by Total Mesorectal Excision (TME) Followed by an Additional Six Cycles of FOLFOX 6.
FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

Colorectal Cancer Screening Clinical Trial using Water infusion; Air insufflation

East Bay Institute for Research and Education - Recruiting 50 years to 80 years.
- Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance.
Water infusion; Air insufflation

Cognition, Fatigue, or Colorectal Neoplasm Clinical Trial using Neuropsychological Testing

University Health Network, Toronto - Recruiting 18 years to 75 years.
- Cognitive Function and Fatigue in Cancer Patients After Chemotherapy: A Longitudinal Controlled Study in Patients With Colorectal Cancer.
Neuropsychological Testing

Colorectal Cancer Clinical Trial using bevacizumab; fluorouracil; irinotecan hydrochloride; leucovorin calcium

National Cancer Institute (NCI) - Recruiting 18 years to 74 years.
- Chemotherapy With FOLFIRI Plus Bevacizumab (AvastinR) in Patients With Metastatic Colorectal Cancer Bearing Genotype UGT1A1*1/UGT1A1*1 or UGT1A1*1/UGT1A1*1/UGT1A1*28: Prospective, Phase II, Multicenter Study.
bevacizumab; fluorouracil; irinotecan hydrochloride; leucovorin calcium

Colorectal Cancer Clinical Trial

Royal Marsden NHS Foundation Trust - Recruiting 18 years or older.
- SS-GCC1- Screening Study of Genetic Changes in Colorectal Cancer.

Colorectal Cancer Clinical Trial using laparoscopic surgery; open surgery

Beijing Friendship Hospital - Recruiting 18 years to 75 years.
- .
laparoscopic surgery; open surgery

Colorectal Surgery Clinical Trial using Transrectal vacuum assisted drainage

Hvidovre University Hospital - Recruiting 18 years or older.
- Transrectal Vacuum Assisted Drainage: A NEW METHOD OF TREATING ANASTOMOTIC LEAKAGE AFTER RECTAL RESECTION. A Prospective Randomized Multicenter Study in Cooperation With 'The Danish Colorectal Cancer Group'.
Transrectal vacuum assisted drainage

Colonic Neoplasms Clinical Trial

Samsung Medical Center - Recruiting N/A or older.
- Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer.

Colorectal Cancer, Liver Neoplasms, Hepatocellular Carcinoma, Gal Clinical Trial using interventionally implanted hepatic arterial port catheter

Charite University, Berlin, Germany - Recruiting 18 years or older.
- Open One-Arm Therapy Optimizing Trial on Regional Chemotherapy of the Liver Through an Interventionally Implanted A.Hepatica Port System in Patients With Liver Metastases or Primary Liver Neoplasms..
interventionally implanted hepatic arterial port catheter