Bayer - Recruiting 18 years or older. - A Randomized Controlled Trial of Rivaroxaban for the Prevention of Major Cardiovascular Events in Patients With Coronary or Peripheral Artery Disease (COMPASS - Cardiovascular OutcoMes for People Using Anticoagulation StrategieS).
Amgen - Recruiting 18 years or older. - A Randomized, Double-Blind, Multi-center, Placebo-controlled, Parallel-group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden as Measured by Intravascular Ultrasound in Subjects Undergoing Coronary Catheterization..
University of Florida - Recruiting 18 years to 74 years. - A Pharmacodynamic Study Comparing Prasugrel Versus Ticagrelor in Patients With Coronary Artery Disease Undergoing PCI With CYP2C19 Loss-of-function Genotypes: A Feasibility Study With Point-of-care Pharmacodynamic and Genetic Testing.
Kips Bay Medical, Inc. - Recruiting 21 years or older. - Post-market Study to Evaluate Post-implant Patency Rates of the eSVS Mesh in the Treatment of Saphenous Vein Graphs During Coronary Artery Bypass Grafting Versus Saphenous Vein Grafts Without the eSVS Mesh Via Coronary Angiography and Duplex Ultra-Sonography Results.
OrbusNeich - Recruiting 20 years or older. - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE): Assessment of a Novel DES Platform For Percutaneous Coronary Revascularization in Patients With Ischemic Coronary Disease and NSTEMI Acute Coronary Syndrome.
OrbusNeich R stentT; Everolimus Eluting Stent (EES)
ECRI bv - Recruiting 21 years or older. - A Single-arm Trial to Evaluate the Effectiveness of PCI of de Novo 3-vessel Disease Applying the SYNTAX Score II With Pressure Wire Functional Assessment and IVUS Guidance, Using an Everolimus-eluting Stent With Biodegradable Abluminal Coating.
Neograft Technologies, Incorporated - Recruiting 18 years to 80 years. - First-In-Human Study to Demonstrate the Preliminary Safety and Efficacy of the Angioshield System to Provide Mechanical Support for Vein Grafts Used in CABG Surgery.
Hellenic Cardiovascular Research Society - Recruiting 18 years to 79 years. - A Single Center Phase II Assessor -Blinded RaNdomised Active Controlled Parallel-Group Trial to COmpare Ticagrelor Versus Clopidogrel on the REduction of ArteriaL STiffness and Wave Reflections in Patients With CoronarY Artery Disease. The NOVELTY Study.
National Taiwan University Hospital - Recruiting 20 years to 75 years. - Using Non-invasive Near Infra-red Spectroscopy to Measure the Regional Tissue Perfusion in Patients Receiving Off-pump Coronary Artery Bypass Graft Surgery.
Imperial College London - Recruiting 18 years to 85 years. - Defining a Gold Standard for Ischaemia: Effects of Interventional Revascularisation Versus Optimum Medical Therapy on Exercise Capacity in Patients With Stable Coronary Artery Disease.
New York University School of Medicine - Recruiting 18 years or older. - Effect of Left Versus Right Radial Artery Access on Radiation Exposure in Patients With Predictors of Potential Trans-radial Access Failure.
Randomized left versus right radial artery approach
Deutsches Herzzentrum Muenchen - Recruiting 18 years or older. - Intracoronary Stenting and Antithrombotic Regimen: Testing of a Six-week Versus a Six-month Clopidogrel Treatment Regimen in Patients With Concomitant Aspirin and Oral Anticoagulant Therapy Following Drug-eluting Stenting.
Novartis - Recruiting 18 years or older. - A Multicenter, Double Blind, Randomized, Parallel Group, Placebo-controlled Study to Evaluate the Effects of Intravenous Serelaxin Infusion on Micro- and Macrovascular Function in Patients With Coronary Artery Disease.
Rigshospitalet, Denmark - Recruiting 18 years or older. - Entire Danish Initiative To ImrpOve Revascularization Strategies (EDITORS) - A Randomised Evaluation of Clinical Outcome After Acute or Deferred Invasive Intervention Integrated With MDCT Imaging in Patients With Acute Coronary Syndromes.
St. Petersburg State Pavlov Medical University - Recruiting 18 years to 80 years. - Influence of the Administration of Autologous Bone Marrow Mononuclear Cells for the Duration of Functioning Aorto-coronary Bypass Grafts in the Surgical Treatment of Coronary Heart Disease.
coronary artery bypass grafting with administration of autologous bone marrow stem cells
Rigshospitalet, Denmark - Recruiting 18 years or older. - CardioPAT Project - Reducing the Need for Allogenic Blood Transfusion After On-pump Cardiac Surgery With Intra- and Postoperative Use of a New Device: a Randomized Trial.
China National Center for Cardiovascular Diseases - Recruiting 18 years or older. - The China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Prospective Study of Revascularization in Patients With Three-vessel Coronary Heart Disease.
Imperial College London - Recruiting 18 years to 90 years. - Prospective, Multi-center, Double Blind, Randomised Study to Test the Safety of Deferral of Stenting in Physiological Non-significant Lesions in a Clinical Population of Intermediate Stenoses Using iFR and FFR.
University of Ottawa Heart Institute - Recruiting 18 years or older. - Ecologically Optimizing Exercise Maintenance in Men and Women Post-Cardiac Rehabilitation: A Randomized Controlled Trial of Efficacy With Economics.
University of Roma La Sapienza - Recruiting 18 years to 80 years. - 'Potential Effect of Acute and Chronic Caffeine Administration on Platelet Reactivity in Patient With Coronary Artery Disease on Dual Antiplatelet Therapy'.
Vitebsk Regional Clinical Hospital - Recruiting 18 years to 80 years. - Comparative Effectiveness of the Minimally Invasive Coronary Artery Bypass Grafting (MICS CABG) Versus Off Pump (OPCABG) and on Pump Coronary Artery Bypass Grafting (ONCABG) in Patients With Multi-vessel Coronary Disease.
National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 85 years. - Preliminary Assessment of Direct Intra-Myocardial Injection of Autologous Bone Marrow-derived Stromal Cells on Patients Undergoing Revascularization for CAD With Depressed Left Ventricular Function.
Janssen Research & Development, LLC - Recruiting 18 years to 95 years. - A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Oral Rivaroxaban With Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects With Chronic Heart Failure and Significant Coronary Artery Disease Following a Hospitalization for Exacerbation of Heart Failure.
Rivaroxaban; Placebo; Standard of care for heart failure and coronary artery disease
Biotronik AG - Recruiting 18 years or older. - BIOLUX RCT - Clinical Performance of the Pantera LUX Paclitaxel Releasing Balloon Versus the Drug Eluting Orsiro Hybrid Stent System in Patients With In-stent Restenosis - a Randomized Controlled Trial.
Municipal Hospital Ostrava - Recruiting 18 years to 75 years. - Official Title Verification of the Safety of Early Discharge (Within 72 Hours) in Low Risk Patients After Acute ST-segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. Open Randomized Study..
University Hospital Heidelberg - Recruiting 18 years to 90 years. - Comprehensive 'Bio-Imaging' Using Quantitative Coronary Plaque Composition Assessment and the High-sensitive Troponin T for the Prediction of Cardiac Outcomes..
Bayer - Recruiting 18 years or older. - Multicenter Open-label Study to Evaluate Efficacy of Gadobutrol-enhanced Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Significant Coronary Artery Disease (CAD) in Subjects With Known or Suspected CAD by a Blinded Image Analysis.
University Hospital, Bordeaux - Recruiting 18 years or older. - Randomized Comparison of Endocardial Versus Epicardial - From the Coronary Sinus - Left Ventricular Pacing for Resynchronization in Heart Failure..
Resynchronization using a transeptal approach; Resynchronization using a coronary sinus approach
Abbott Vascular - Recruiting 18 years or older. - Evaluate the Continued Safety and Effectiveness of the XIENCE PRIME EECSS in a Cohort of Real-world Patients Receiving the XIENCE PRIME EECSS During Commercial Use..
XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
National Taiwan University Hospital - Recruiting 30 years to 70 years. - Development and Evaluation of a Web-based Group Cognitive-behavioral Therapy Program for Coronary Artery Heart Disease Patients.
Sino Medical Sciences Technology Inc. - Recruiting 18 years or older. - A Prospective, Multicenter, RAndomized, CoNtrolled, Study Comparing the Safety and Efficacy Between BuMA eG Based BioDegradable Polymer Stent and EXCEL Biodegradable Polymer Sirolimus-eluting Stent in 'ReAl-World' Practice (PANDA-III).
JW Medical Systems Ltd - Recruiting 18 years to 75 years. - A Prospective Multicenter Single-Arm Observational Registry Study to Assess the Safety and Efficacy of EXCEL-II With Sirolimus Eluting Stent for the Treatment of Patients With de Novo Coronary Artery . (CREDIT-III Trial).
University of Roma La Sapienza - Recruiting 18 years to 90 years. - 'Impact of Cigarette Smoking on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With P2Y12 Inhibitors' - Trial COPTER -.
Rigshospitalet, Denmark - Recruiting 50 years or older. - Myocardial Perfusion 320 MDCT Guided Treatment Strategy for the Clinical Management of Patient With Recent Acute-onset Chest Pain. A Randomized Controlled Trial.
Medical Care Center Prof. Mathey, Prof. Schofer, Ltd. - Recruiting 18 years to 75 years. - Postmarketing Surveillance Registry to Monitor Everolimus-eluting Bioresorbable Vascular Scaffold Following Rotational Atherectomy for the Treatment of Complex Coronary Lesions - The ASSURE ROT Registry.
Deutsches Herzzentrum Muenchen - Recruiting 18 years or older. - Intracoronary Scaffold Assessment a Randomised Evaluation of Absorb in Myocardial Infarction (ISAR-Absorb MI) A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction.
Capital District Health Authority, Canada - Recruiting 20 years to 75 years. - The Effects of a 12-week Cardiovascular Rehabilitation Exercise Program on Inflammatory Markers and Traditional Coronary Artery Disease Risk Factors in Patients With Rheumatoid Arthritis.
Duke University - Recruiting 45 years to 75 years. - Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Haukeland University Hospital - Recruiting 18 years to 80 years. - Ringer`s Acetat Versus Balanced Hydroxyethyl-starch as Primesolution in the Heart-lung Maschine During Cardio-pulmonary-bypass. Postoperatively Fluid Balance and Cardiac Function.
Kuopio University Hospital - Recruiting 30 years to 80 years. - Endocardial VEGF-D Gene Therapy for the Treatment of Severe Coronary Heart Disease - A Phase 1 Single-blinded Placebo-controlled Phase 1 Clinical Trial.
Medtronic Vascular - Recruiting 18 years or older. - Resolute Integrity US A Postapproval Study of the Medtronic ResoluteT Integrity Zotarolimus-Eluting Coronary Stent System in the Treatment of De Novo Lesions in Native Coronary Arteries With a Reference Vessel Diameter of 2.25 mm to 4.2 mm.
Maastricht University Medical Center - Recruiting 18 years or older. - Maastricht Biomarker CT Study. Relation Between Cardiovascular Biomarkers and Coronary Atherosclerosis in Patients Undergoing Multi Detector Cardiac Computed Tomography..
Svelte Medical Systems Europe - Recruiting 18 years or older. - Acrobat Coronary Stent System Effectiveness European Study (European Multicenter Effectiveness Randomized Study of Svelte Medical Systems Acrobat Stent on a Wire Compared to Other BMS PCI in de Novo Coronary Lesions) ACES Trial.
Rapid City Regional Hospital, Inc - Recruiting 18 years or older. - A Single Center, Randomized, Open Label, Multiple Dose, Crossover Study of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients With Stable Coronary Artery Disease.
University of Roma La Sapienza - Recruiting 18 years or older. - PROgenitor Cells Role in Restenosis and Progression of Coronary ATherosclerosis After Percutaneous Coronary Intervention (PROCREATION) Study.
Cardiovascular Institute & Fuwai Hospital - Recruiting 18 years to 75 years. - Investigator Initiated Prospective Study to Investigate the Best Anti-platelet Treatment in High Thrombotic Risk PCI Patients..
The First Hospital of Nanjing Medical University - Recruiting 18 years to 75 years. - Safety and Effectiveness Study of Percutaneous Catheter-based Renal Sympathetic Denervation as a Method of Secondary Prevention for Patients After Percutaneous Coronary Intervention..
St. Louis University - Recruiting 18 years or older. - Utilization of Lexiscan (Regadenoson)in the Cardiac Catheterization Lab to Achieve Maximal Hyperemia for Coronary Physiologic Assessment With Fractional Flow Reserve.
Johannes Gutenberg University Mainz - Recruiting 18 years to 75 years. - Effects of Clopidogrel vs Prasugel vs Ticagrelor on Endothelial Function, Inflammatory and Oxidative Stress Parameters and Platelet Function in Patients Undergoing Coronary Artery Stenting. A Randomised, Prospective Study..
University of Alberta - Recruiting 18 years or older. - Assessment of Patients With Suspected CAD: What is the Best Initial Imaging Strategy? Cardiac Computed Tomographic Angiography,(CCTA) vs Stress Echocardiography (SE) vs SPECT.
Kyoto University, Graduate School of Medicine - Recruiting 20 years or older. - Intensive Blood Pressure and LDL Lowering for Better Survival and Cardiovascular Outcome in Diabetic Patients With Coronary Artery Disease: Randomized Controlled Trial.
Cardiocentro Ticino - Recruiting N/A or older. - Incremental Value of Signal Processed Surface Electrocardiography (IECG) for Detecting Ischemic Heart Disease: Comparison With Computed Tomography Coronary Angiography (CTCA).
Chinese PLA General Hospital - Recruiting 18 years to 75 years. - A Prospective,Randomized, Placebo-Controlled Study of Intramyocardial Injection of Autologous Bone-Marrow Mononuclear Cells in Patients With Severe, Chronic Ischemic Heart Disease Undergoing Coronary Bypass Surgery.
bone marrow mononuclear cells injection; placebo intramyocardial injection
Taichung Veterans General Hospital - Recruiting 18 years to 70 years. - Screen of Diabetes Mellitus by Oral Glucose Tolerance Test in Subjects Receiving Catheterization or Multi-detector Computed Tomography (MDCT) for Coronary Artery Disease.
UMC Utrecht - Recruiting 18 years to 80 years. - Randomized Comparison of Drug Eluting Balloon/Bare Metal Stent Versus Drug Eluting Stent Versus Bare Metal Stent for the Treatment of Patients With Acute ST-elevation Myocardial Infarction.
Drug eluting balloon; Bare metal stent; Drug eluting stent
Harbin Medical University - Recruiting 18 years to 75 years. - Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for Surface Coverage After Two Types of Drug-eluting Stent Implantation (A Pilot Study).
Clearstream Technologies Ltd. - Recruiting 18 years or older. - OCT Evaluation of Stent Struts Re-endothelization in Patients With Acute Coronary Syndromes: a Comparison of the IntrepideT Stent vs. TaxusT.
Intrepide Trapidil eluting stent; Taxus drug eluting stent
Samsung Medical Center - Recruiting 18 years or older. - Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion? (COPE Study): Long-Term Follow-up Study.
A.O. Ospedale Papa Giovanni XXIII - Recruiting 18 years or older. - In-Vivo Vascular Response of Sirolimus-,Paclitaxel- and Zotarolimus-Eluting Stents in Long Lesions Requiring Overlapping. A Prospective, Randomized, Controlled Study Using Optical Coherence Tomography.
sirolimus drug eluting coronary stent CypherT (Cordis Corp, Johnson & Johnson Co); paclitaxel polymer drug eluting stent Taxus LibertT (Boston Scientific, Natick MS); zotarolimus drug eluting coronary stent EndeavorT (Medtronic, Santa Rosa, CA); Libert bare metal coronary stent LibertT BMS(Boston Scientific, Natick, MS)
Heart Center Bad Krozingen - Recruiting 18 years or older. - Prospective, Randomized, Single-Center Evaluation of the CypherT Sirolimus Eluting Coronary Stent System in the Treatment of Bifurcated Coronary Lesions.
PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique