64 results found.

Bipolar Disorder, Major Depressive Episode, or Suicidal Ideation Clinical Trial using Ketamine; Midazolam

New York State Psychiatric Institute - Recruiting 18 years to 65 years.
- Ketamine vs. Midazolam in Bipolar Depression.
Ketamine; Midazolam

Major Depressive Disorder, or Depressive Symptoms Clinical Trial using Memory Specificity Training; Education and Support

Medical Research Council - Recruiting 18 years to 65 years.
- A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression.
Memory Specificity Training; Education and Support

Major Depressive Disorder Clinical Trial using desvenlafaxine succinate sustained release; fluoxetine; placebo

Pfizer - Recruiting 7 years to 17 years.
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Fluoxetine-Referenced, Parallel-Group Study To Evaluate The Safety, Efficacy, And Tolerability Of DVS SR In Children And Adolescent Outpatients With Major Depressive Disorder.
desvenlafaxine succinate sustained release; fluoxetine; placebo

Major Depressive Disorder Clinical Trial using DVS SR

Pfizer - Recruiting 7 years to 18 years.
- A 6-Month, Open-Label, Multi-Center, Flexible-Dose Extension Study to the B2061014 Study to Evaluate the Safety, Tolerability and Efficacy of Desvenlafaxine Succinate Sustained-Release (DVS SR) Tablets in the Treatment of Children and Adolescent Outpatients With Major Depressive Disorder.
DVS SR

Major Depressive Disorder, or Vasomotor Symptoms Clinical Trial using desvenlafaxine succinate

Pfizer - Recruiting 18 years or older.
- An Open Label, Non-Interventional Study of the Safety of Desvenlafaxine Succinate (Pristiq) in the Treatment of Major Depressive Disorder (MDD) and Vasomotor Symptoms (VMS) Associated With Menopause in Filipino Adult Patients: a Post Marketing Surveillance Study.
desvenlafaxine succinate

Major Depressive Disorder Clinical Trial using Desvenlafaxine Succinate Sustained-Release; Placebo

Pfizer - Recruiting 7 years to 17 years.
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study To Evaluate the Efficacy, Safety And Tolerability Of Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Children And Adolescent Outpatients With Major Depressive Disorder.
Desvenlafaxine Succinate Sustained-Release; Placebo

Major Depressive Disorder Clinical Trial using DVS SR

Pfizer - Recruiting 7 years to 18 years.
- A 6 Month, Open Label, Multi Center, Flexible Dose Extension Study To The B2061032 Study To Evaluate The Safety, Tolerability And Efficacy Of Desvenlafaxine Succinate Sustained Release (DVS SR) Tablets In The Treatment Of Children And Adolescent Outpatients With Major Depressive Disorder.
DVS SR

Major Depressive Disorder Clinical Trial using Mirtazapine

Lawson Health Research Institute - Recruiting 50 years to 90 years.
- Does LEPR Polymorphism Predict Variability in Weight Gain Induced by Mirtazapine in the Treatment of Late Life Depression?.
Mirtazapine

Depression Disorder, Major Clinical Trial using RO4995819; Placebo

Hoffmann-La Roche - Recruiting 18 years to 65 years.
- A Multi Center, Randomized, Double-blind, Placebo Controlled, Parallel-group Study to Investigate the Efficacy and Safety of RO4995819 Versus Placebo, as Adjunctive Therapy in Patients With Major Depressive Disorder Having Inadequate Response to Ongoing Antidepressant Treatment (ARTDeCo).
RO4995819; Placebo

Major Depressive Disorder Clinical Trial using LY03005; Placebo

Luye Pharma Group Ltd. - Recruiting 18 years to 45 years.
- A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Single Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03005.
LY03005; Placebo

Major Depressive Disorder Clinical Trial

Stanford University - Recruiting 21 years to 70 years.
- Identifying Biological Markers for Severe Depression.

Major Depression Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Brain Inflammation In Major Depressive Disorder.

Major Depressive Disorder Clinical Trial using Pramipexole

New York State Psychiatric Institute - Recruiting 18 years to 50 years.
- Ventrostriatal Dopamine Release and Reward Motivation in MDD.
Pramipexole

Major Depressive Disorder, or Healthy Clinical Trial using PET scan; Rolipram

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 55 years.
- Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE 4) in Depressed Patients.
PET scan; Rolipram

Depression Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- An Investigation to Determine Whether Levels of P11 Protein in Peripheral Blood Cells Correlate With Treatment Response to Citalopram in Patients With Major Depressive Disorder.

Major Depressive Disorder Clinical Trial using Genecept Assay

Genomind, LLC - Recruiting 18 years to 65 years.
- A Six-month Study of the Genecept Assay vs. Treatment as Usual to Evaluate Efficacy of Using Assay Guided Treatment in Outpatient Adults With Treatment Resistant Depression.
Genecept Assay

Depression Clinical Trial using Diazoxide

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- A Pathophysiological Study to Determine if Enhancing Glutamate Transporter Function Produces Antidepressant Effects in Patients With Major Depressive Disorder.
Diazoxide

Major Depressive Disorder Clinical Trial using Etomidate; Propofol; Bilateral temporal MECT; The right temporal MECT; Bilateral frontal MECT

Shanghai Mental Health Center - Recruiting 18 years or older.
- The Efficacy And Cognitive Impairment Of Modified Electroconvulsive Therapy: A Randomized Clinical Trial And Its Standard Technology Promotion Research.
Etomidate; Propofol; Bilateral temporal MECT; The right temporal MECT; Bilateral frontal MECT

Major Depressive Disorder Clinical Trial using HFL rTMS; iTBS

Centre for Addiction and Mental Health - Recruiting 18 years to 59 years.
- A Randomized Controlled Study of Conventional Versus Theta Burst Repetitive Transcranial Magnetic Stimulation in the Treatment of Major Depressive Disorder.
HFL rTMS; iTBS

Anxiety Depression (Mild or Not Persistent), Major Depressive Dis Clinical Trial using Psychosocial Counseling; Usual Care

Universit„tsklinikum Hamburg-Eppendorf - Recruiting 18 years to 65 years.
- Self-Management Support in Primary Care.
Psychosocial Counseling; Usual Care

Major Depressive Disorder, or Dysthymic Disorder Clinical Trial using Combined Cognitive Behavioral and Dilemma-Focused Therapy; Cognitive Behavioral Therapy for Depression

University of Barcelona - Recruiting 18 years to 70 years.
- Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused Intervention.
Combined Cognitive Behavioral and Dilemma-Focused Therapy; Cognitive Behavioral Therapy for Depression

Depressive Disorder, Major Clinical Trial using Whole Body Hyperthermia system

University of Arizona - Recruiting 18 years to 65 years.
- Whole Body Hyperthermia and Major Depression (MDD).
Whole Body Hyperthermia system

Major Depressive Disorder, Major Depressive Disorder, Recurrent, Clinical Trial using Escitalopram oxalate; transcranial direct current stimulation

University of Sao Paulo - Recruiting 18 years to 75 years.
- Escitalopram and Transcranial Direct Current Stimulation in Major Depressive Disorder: a Double-blind, Placebo-controlled, Randomized, Non-inferiority Trial.
Escitalopram oxalate; transcranial direct current stimulation

Major Depressive Disorder, or Treatment Resistant Depression Clinical Trial using Deep Brain Stimulation Model 3387 Model 3389

The University of Texas Health Science Center, Houston - Recruiting 22 years to 65 years.
- Deep Brain Stimulation (DBS) Therapy for Treatment Resistant.
Deep Brain Stimulation Model 3387 Model 3389

Bipolar Disorder Clinical Trial using FK949E; Placebo

Astellas Pharma Inc - Recruiting 20 years to 64 years.
- Phase II/III Study of FK949E - Placebo-controlled, Double-blind, Parallel-group Comparative Study and Open-label, Non-controlled Extension Study in Bipolar Disorder Patients With Major Depressive Episodes -.
FK949E; Placebo

Major Depressive Disorder Clinical Trial using psychometric tests; MRI; transcranial doppler and TPI; explicitative interview

University Hospital, Tours - Recruiting 18 years to 55 years.
- Comparative Study of Physiological and Cerebrovascular Reactivity in Depression, at the Three Phases of Emotion.
psychometric tests; MRI; transcranial doppler and TPI; explicitative interview

Major Depressive Disorder Clinical Trial using Treatment with SSRI

University of California, San Francisco - Recruiting 18 years to 70 years.
- Neurosteroid Metabolism and the Antidepressant Effects of Serotonin Specific Reuptake Inhibitors (SSRI's).
Treatment with SSRI

Major Depressive Disorder With Mixed Features Clinical Trial using Lurasidone; Placebo

Sunovion - Recruiting 18 years to 75 years.
- A Randomized, 6-Week, Double-Blind, Placebo-Controlled, Flexible-Dose, Parallel-Group Study of Lurasidone for the Treatment of Major Depressive Disorder With Mixed Features.
Lurasidone; Placebo

Major Depressive Disorder Clinical Trial using rTMS; Sham Device

Department of Veterans Affairs - Recruiting 18 years to 70 years.
- CSP #556 - The Effectiveness of rTMS in Depressed VA Patients.
rTMS; Sham Device

Major Depressive Disorder Clinical Trial using Placebo; Brexpiprazole

H. Lundbeck A/S - Recruiting 18 years to 75 years.
- Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose Long-term Study to Evaluate the Maintenance of Efficacy and Safety of 1 to 3 mg/Day of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment.
Placebo; Brexpiprazole

Major Depressive Disorder Clinical Trial using Citalopram

New York State Psychiatric Institute - Recruiting 24 years to 75 years.
- Placebo Effects in the Treatment of Depression: Cognitive and Neural Mechanisms.
Citalopram

Depressive Disorder, Major Clinical Trial using Active Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator; Inactive Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator

Cervel Neurotech, Inc. - Recruiting 18 years to 70 years.
- A Prospective, Double-Blind, Randomized, Parallel-Group, Sham-Controlled Feasibility Trial of Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Major Depressive Disorder.
Active Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator; Inactive Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator

Major Depressive Disorder Clinical Trial using CERC-301; Placebo

Cerecor Inc - Recruiting 18 years to 70 years.
- A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Study of CERC-301 in the Adjunctive Treatment of Subjects With Severe Depression and Recent Active Suicidal Ideation Despite Antidepressant Treatment.
CERC-301; Placebo

Major Depressive Disorder, Anxiety, or Comorbidity Clinical Trial using Vilazodone; Citalopram

Massachusetts General Hospital - Recruiting 18 years to 50 years.
- The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives.
Vilazodone; Citalopram

Major Depressive Disorder Clinical Trial using venlafaxine ER 75 mg/day (fixed dose); venlafaxine ER 75 mg/day to 225 mg/day (flexible dose); Placebo

Pfizer - Recruiting 20 years or older.
- A Randomized, Double-Blind, Placebo Controlled, Multicenter Study To Evaluate The Efficacy And Safety Of Venlafaxine ER In Adult Outpatients With Major Depressive Disorder.
venlafaxine ER 75 mg/day (fixed dose); venlafaxine ER 75 mg/day to 225 mg/day (flexible dose); Placebo

Major Depressive Disorder (MDD), or Anxiety Disorder Clinical Trial using Escitalopram

Medical University of Vienna - Recruiting 18 years to 50 years.
- Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders.
Escitalopram

Major Depressive Disorder Clinical Trial using Venlafaxine ER

Pfizer - Recruiting 20 years or older.
- A Open-Label Long-Term Extension Study To Evaluate The Safety And Efficacy Of Venlafaxine Er In Adult Outpatients With Major Depressive Disorder.
Venlafaxine ER

Major Depressive Disorder, or Anxiety Clinical Trial using Brexpiprazole

Otsuka Pharmaceutical Development & Commercialization, Inc. - Recruiting 18 years to 65 years.
- Protocol 331-13-002: An Exploratory, Multicenter, Open-label, Flexible-dose Trial of Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms.
Brexpiprazole

Major Depressive Disorder, Recurrent, Mild, or Depressive Disorde Clinical Trial using Transcranial Magnetic Stimulation (TMS); Magnetic Resonance Spectroscopy and Imaging

Mayo Clinic - Recruiting 10 years to 18 years.
- Cortical Excitability and Inhibition in Children and Adolescents With Major Depressive Disorder.
Transcranial Magnetic Stimulation (TMS); Magnetic Resonance Spectroscopy and Imaging

Major Depressive Disorder Clinical Trial using Repetitive transcranial magnetic stimulation (rTMS)

Mayo Clinic - Recruiting 13 years to 18 years.
- A Randomized, Double-Blinded, Sham-Controlled Trial of Repetitive Transcranial Magnetic Stimulation in Depressed Adolescents.
Repetitive transcranial magnetic stimulation (rTMS)

Depressive Disorder, Major, Bipolar Disorder, Panic Disorder, or Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders.

Major Depressive Disorder Clinical Trial using Cognitive Therapy; Supportive-Expressive Psychodynamic Therapy

University of Pennsylvania - Recruiting 18 years to 65 years.
- A Comparison of Cognitive and Dynamic Therapy for MDD in Community Settings.
Cognitive Therapy; Supportive-Expressive Psychodynamic Therapy

Major Depressive Disorder (MDD) Clinical Trial using Amisulpride; Placebo

Mclean Hospital - Recruiting 18 years to 45 years.
- The Effects of Dopamine on Reward Processing.
Amisulpride; Placebo

Major Depressive Disorder Clinical Trial using Escitalopram; Healthy Control

Wyss Institute at Harvard University - Recruiting 18 years to 65 years.
- Exploring Biomarkers for Depression.
Escitalopram; Healthy Control

Major Depressive Disorder Clinical Trial using Family psychoeducation

Nagoya City University - Recruiting 18 years to 85 years.
- Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression: A Randomized Controlled Trial.
Family psychoeducation

Major Depressive Disorder, Bipolar Disorder, or Biomarker Panel Clinical Trial using MDDScoreTM

University of Utah - Recruiting 13 years to 21 years.
- Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel.
MDDScoreTM

Major Depressive Disorder Clinical Trial using GUILT-INCREASE-CORRELATION; GUILT-STABILIZE-CORRELATION

D'Or Institute for Research and Education - Recruiting 18 years to 65 years.
- Rebalancing Blame Using fMRI Neurofeedback: a Double-blind Controlled Clinical Proof-of-concept Trial in Remitted Major Depressive Disorder.
GUILT-INCREASE-CORRELATION; GUILT-STABILIZE-CORRELATION

Major Depressive Disorder Clinical Trial using desvenlafaxine

University of British Columbia - Recruiting 19 years to 55 years.
- Neurocognition and Work Productivity in Major Depressive Disorder.
desvenlafaxine

Major Depressive Disorder, or Suicidality Clinical Trial using paliperidone; lithium

University of Alabama at Birmingham - Recruiting 19 years to 65 years.
- Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation.
paliperidone; lithium

Major Depressive Disorder, or Dysthymia Clinical Trial using Cognitive Behavior Therapy for Depression

New York State Psychiatric Institute - Recruiting 18 years to 70 years.
- Psychological Mindedness as a Predictor of Success in CBT for Depressed Patients.
Cognitive Behavior Therapy for Depression

Major Depressive Disorder Clinical Trial using Creatine monohydrate or placebo

University of Utah - Recruiting 13 years to 21 years.
- Placebo-Controlled Dose-Ranging Trial of Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder: a Magnetic Resonance Spectroscopy Study.
Creatine monohydrate or placebo

Major Depression, Cancer, Diabetes, or Cardiovascular Diseases Clinical Trial using Desvenlafaxine; Omega 3 Fatty acids; Placebo (for Omega 3 fatty acid supplement)

University of Connecticut Health Center - Recruiting 18 years or older.
- A Randomized, Double-Blind Placebo-controlled Study Evaluating the Efficacy of Omega 3 Fatty Acid Augmentation of Desvenlafaxine for the Treatment of Major Depressive Disorder in Patients With Medical Illness..
Desvenlafaxine; Omega 3 Fatty acids; Placebo (for Omega 3 fatty acid supplement)

Major Depressive Disorder Clinical Trial using tranylcypromine

New York State Psychiatric Institute - Recruiting 18 years to 65 years.
- Developing a Biomarker to Predict Response in Treatment Resistant Depression.
tranylcypromine

Bipolar Disorder, or Major Depressive Disorder Clinical Trial using Enhanced Care; Family-Focused Treatment

University of California, Los Angeles - Recruiting 9 years to 17 years.
- Early Intervention for Youth at Risk for Bipolar Disorder.
Enhanced Care; Family-Focused Treatment

Major Depressive Disorder Clinical Trial using Aripiprazole

Taiwan Otsuka Pharm. Co., Ltd - Recruiting 20 years to 65 years.
- Aripiprazole for the Augmentation of Antidepressant Therapy: An Observational, Outpatients Study in Inadequate Responders Diagnosed With Major Depressive Disorder.
Aripiprazole

Major Depressive Disorder Clinical Trial using Venlafaxine; bupropion; escitalopram; Psychotherapy; Duloxetine

St. Joseph's Healthcare Hamilton - Recruiting 18 years to 70 years.
- EEG Signal Processing as a Predictor of Antidepressant Response.
Venlafaxine; bupropion; escitalopram; Psychotherapy; Duloxetine

Depression, Psychotic Disorders, or Depressive Disorder, Major Clinical Trial

Stanford University - Recruiting 18 years to 85 years.
- Hypothalamic-Pituitary-Adrenal (HPA)/ Dopamine Axis in Psychotic Depression.

Depressive Disorder, Major Clinical Trial using escitalopram

Sheba Medical Center - Recruiting 18 years to 65 years.
- .
escitalopram

Major Depressive Disorder Clinical Trial using SSRI; CBT

University of Pittsburgh - Recruiting 18 years to 55 years.
- Imaging Antidepressant vs. Cognitive Behavior Therapy Effects on Unipolar Depression.
SSRI; CBT

Psychotic Disorders, Depressive Disorder, or Depressive Disorder, Clinical Trial

Stanford University - Recruiting N/A or older.
- Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression.

Major Depressive Disorder Clinical Trial using TMS; Sham TMS

Bayside Health - Recruiting 18 years to 85 years.
- A Double-Blind Sham Controlled Trial of rTMS in Treatment Resistant Major Depression.
TMS; Sham TMS

Bipolar Disorder, or Major Depressive Disorder Clinical Trial using ropinirole

Sheba Medical Center - Recruiting 18 years or older.
- A Placebo Controlled Trial of the Dopamine D-2 Receptor Agonist Ropinirole in Treatment of 60 Patients With Refractory Bipolar I and II Depression..
ropinirole

Major Depressive Disorder Clinical Trial using Standard Quality Improvement; Patient-centered Intervention

Agency for Healthcare Research and Quality (AHRQ) - Recruiting 18 years to 75 years.
- Patient-Centered Depression Care for African Americans.
Standard Quality Improvement; Patient-centered Intervention