300 results found.

Hereditary Neoplastic Syndrome, or Tuberous Sclerosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- Cutaneous Tumorigenesis in Patients With Tuberous Sclerosis.

Myelodysplastic Syndrome Clinical Trial using Antibiotic and antifungal drugs

Gruppo Italiano Malattie EMatologiche dell'Adulto - Recruiting 18 years or older.
- Observational Prospective Multicenter Study to Evaluate the Infective Risk in Myelodysplastic Syndrome Patients: Antimicrobial Prophylaxis and Granulocyte Growth Factors..
Antibiotic and antifungal drugs

Systemic Lupus Erythematosus, or Antiphospholipid Syndrome Clinical Trial

Hospital for Special Surgery, New York - Recruiting 18 years to 45 years.
- Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS).

Tourette Disorder, or Tourette Syndrome Clinical Trial using placebo; extended-release guanfacine (Intuniv)

Yale University - Recruiting 6 years to 17 years.
- Guanfacine in Children With Tic Disorders: A Multi-site Study.
placebo; extended-release guanfacine (Intuniv)

Glomerulonephritis, Lupus Nephritis, Membranous Glomerulonephriti Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 5 years or older.
- Studies of Immunologically-Mediated Kidney Diseases.

Hematological Malignancies, Certain Lysosomal Storage and Peroxis Clinical Trial using A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)

Center for International Blood and Marrow Transplant Research - Recruiting N/A or older.
- A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications.
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)

Mucopolysaccharidosis II, MPS II, or Hunter Syndrome Clinical Trial

Shire Development LLC - Recruiting 2 years to 18 years.
- A Prospective, Longitudinal, Observational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II).

Community Acquired Respiratory Disease Syndrome Clinical Trial using Methylprednisolone

Department of Veterans Affairs - Recruiting 18 years or older.
- CSP #574 - Extend Steroid (in) CAP(e) (ESCAPe): A Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Evaluate the Safety and Efficacy of Methylprednisolone in Hospitalized Veterans With Severe Community-Acquired Pneumonia.
Methylprednisolone

Rett Syndrome Clinical Trial using dextromethorphan; placebo

Hugo W. Moser Research Institute at Kennedy Krieger, Inc. - Recruiting 2 years to 10 years.
- Placebo Controlled Trial of Dextromethorphan in Rett Syndrome.
dextromethorphan; placebo

Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflam Clinical Trial using ACZ885

Novartis - Recruiting N/A to 4 years.
- A One-year Open-label, Multicenter Trial to Assess Efficacy, Safety and Tolerability of Canakinumab (ACZ885) and the Efficacy and Safety of Childhood Vaccinations in Patients Aged 4 Years or Younger With Cryopyrin Associated Periodic Syndromes (CAPS).
ACZ885

Acute Coronary Syndrome With ST Elevation on Electrocardiogram, A Clinical Trial

Niguarda Hospital - Recruiting 18 years to 80 years.
- Evaluation of Tryptase as a Biomarker of Coronary Heart Disease.

Traumatic Brain Injury With Brief Loss of Consciousness, or Post- Clinical Trial using Hyperbaric oxygen (HBO2) at 1.5 atms; Sham control 1.2 atms

U.S. Army Medical Research and Materiel Command - Recruiting 18 years to 65 years.
- Brain Injury and Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms After Mild Traumatic Brain Injury (BIMA) Protocol.
Hyperbaric oxygen (HBO2) at 1.5 atms; Sham control 1.2 atms

Long QT Syndrome Clinical Trial

Pediatrix Medical Group - Recruiting N/A to 20 years.
- Multicenter Evaluation of Children and Young Adults With Genotype Positive Long QT Syndrome.

Marfan Syndrome Clinical Trial using Irbesartan 150-300mg capsules daily for 6 months; Doxycycline 100-200mg capsules daily for 6 months; Doxycycline placebo capsules daily for 6 months; Irbesartan placebo capsules daily for 6 months

University of Oxford - Recruiting 13 years or older.
- A Randomised, Double-blind, Placebo-controlled Pilot Trial of Irbesartan, Doxycycline and a Combination on Markers of Vascular Dysfunction in the Marfan Syndrome, Using Cardiovascular Magnetic Resonance Imaging.
Irbesartan 150-300mg capsules daily for 6 months; Doxycycline 100-200mg capsules daily for 6 months; Doxycycline placebo capsules daily for 6 months; Irbesartan placebo capsules daily for 6 months

Myelodysplastic Syndromes, or Leukemia, Myelomonocytic, Chronic Clinical Trial using Azacitidine; Volasertib

Boehringer Ingelheim - Recruiting 18 years or older.
- An Open Label Phase I Dose Escalation Trial to Investigate the Maximum Tolerated Dose, Safety, Pharmacokinetics and Efficacy of Intravenous Volasertib in Combination With Subcutaneous Azacitidine in Patients With Previously Untreated High-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) Ineligible for High-intensity Therapy.
Azacitidine; Volasertib

Leukemia, or Lymphoma Clinical Trial using Rasburicase; Allopurinol

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Randomized Phase 2 Study to Evaluate the Efficacy of Rasburicase in Patients at Risk for TLS During Two Cycles of Chemotherapy.
Rasburicase; Allopurinol

Kidney Disease, Nephrotic Syndrome, Glomerular Disease, Glomerulo Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- The Nephrotic Syndrome Study Network (NEPTUNE).

Disorder Related to Bone Marrow Transplantation, Leukemia, or Tra Clinical Trial using Fludarabine; Clofarabine; Busulfan; Thymoglobulin; Stem Cell Infusion; Tacrolimus; Methotrexate

M.D. Anderson Cancer Center - Recruiting 3 years to 70 years.
- A Randomized Study of Once Daily Fludarabine-Clofarabine Versus Fludarabine Alone Combined With Intervenous Busulfan Followed by Allogeneic Hemopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS).
Fludarabine; Clofarabine; Busulfan; Thymoglobulin; Stem Cell Infusion; Tacrolimus; Methotrexate

Keratoconjunctivitis Sicca, or Dry Eye Syndrome Clinical Trial using dexamethasone, artificial tears

Baylor College of Medicine - Recruiting 18 years or older.
- Effects of Conventional Dry Eye Treatments on the Ocular Surface Response to Low Humidity Environment in Patients With Keratoconjunctivitis Sicca..
dexamethasone, artificial tears

Down Syndrome Clinical Trial using ELND005; Placebo

Elan Pharmaceuticals - Recruiting 18 years to 45 years.
- A 4-Week Randomized, Double-Blind, Placebo-Controlled, Phase 2a Safety and PK Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia.
ELND005; Placebo

Endogenous Cushing's Syndrome Clinical Trial using COR-003

Cortendo AB - Recruiting 18 years or older.
- An Open Label Study to Assess the Safety and Efficacy of COR--003 (2S, 4R-ketoconazole) in the Treatment of Endogenous Cushing's Syndrome.
COR-003

Fragile X Syndrome Clinical Trial using acamprosate; Placebo

Children's Hospital Medical Center, Cincinnati - Recruiting 5 years to 23 years.
- Double-Blind, Placebo-Controlled Proof of Concept Study in Youth With Fragile X Syndrome.
acamprosate; Placebo

Williams Syndrome Clinical Trial

Massachusetts General Hospital - Recruiting 14 years to 70 years.
- Characterization of Fat Distribution and Glucose Metabolism in Individuals With and Without Williams Syndrome.

Acute Respiratory Distress Syndrome (ARDS) Clinical Trial using PEEP of 5 or 15 cm H2O

Hospices Civils de Lyon - Recruiting 18 years or older.
- Bedside Assessment of PEEP-induced Lung Recruitment by Using Digital Chest-X-ray in ARDS Patients. A Multicenter Prospective Study..
PEEP of 5 or 15 cm H2O

Atrial Fibrillation, or Acute Coronary Syndrome Clinical Trial using Ticagrelor + Apixaban + ASA; Ticagrelor + Apixaban

Medical University of Vienna - Recruiting 18 years to 40 years.
- The Effect of Ticagrelor and Apixaban With or Without Acetylsalicylic Acid on Markers of Coagulation Activation at the Site of Thrombus Formation in Vivo in Healthy Male Subjects and in an ex Vivo Perfusion Chamber Model at High and Low Shear Rate.
Ticagrelor + Apixaban + ASA; Ticagrelor + Apixaban

Basal Cell Carcinoma Clinical Trial

Genentech - Recruiting 18 years or older.
- A Prospective Observational Study of Treatment Patterns and Effectiveness and Safety Outcomes in Advanced Basal Cell Carcinoma and Basal Cell Carcinoma Nevus Syndrome Patients.

Multiple Sclerosis Clinical Trial using Vitamin D; Placebo; Imaging; Lumbar puncture; Blood sampling; Urine samples

Centre Hospitalier Universitaire de NÄ«mes - Recruiting 18 years to 50 years.
- Multicentric, Randomized, Double-blind Versus Placebo Study Evaluating the Efficacy of Treatment With Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of Multiple Sclerosis (MS) After a Clinically Isolated Syndrome (CIS). Comparison of Conversion Rates After 2 Years..
Vitamin D; Placebo; Imaging; Lumbar puncture; Blood sampling; Urine samples

POEMS Syndrome Clinical Trial using Lenalidomide, Dexamethasone

Peking Union Medical College Hospital - Recruiting 18 years or older.
- An Open-label Phase II Study to Determine the Efficacy and Safety of Lenalidomide Plus Dexamethasone (LDex) in Patients With Newly Diagnosed POEMS Syndrome.
Lenalidomide, Dexamethasone

Coronary Artery Disease, or Acute Coronary Syndrome Clinical Trial using Ticagrelor 180mg; Prasugrel 10mg; Ticagrelor 90mg

University of Florida - Recruiting 18 years to 74 years.
- Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor: The SWAP (SWitching Anti Platelet)-3 Study.
Ticagrelor 180mg; Prasugrel 10mg; Ticagrelor 90mg

Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, or Myelodys Clinical Trial using Allopurinol; Keppra; Busulfan; Cyclophosphamide; Cyclosporine A; Mycophenolate mofetil; Allogeneic hematopoietic stem cell transplant; Filgrastim; antithymocyte globulin

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 44 years.
- Busulfan and Cyclophosphamide Followed By Allogeneic Hematopoietic Cell Transplantation In Patients With Hematological Malignancies.
Allopurinol; Keppra; Busulfan; Cyclophosphamide; Cyclosporine A; Mycophenolate mofetil; Allogeneic hematopoietic stem cell transplant; Filgrastim; antithymocyte globulin

Li-Fraumeni Syndrome, or Cardiovascular Capacity Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Metabolic Regulation by Tumor Suppressor p53 in Li-Fraumeni Syndrome.

Hurler Syndrome Clinical Trial using IRT Laronidase

Masonic Cancer Center, University of Minnesota - Recruiting 6 Months to 3 years.
- Intrathecal Enzyme Replacement Therapy For Patients With Mucopolysaccharidosis Type I (Hurler Syndrome).
IRT Laronidase

T-cell Lymphomas, T-cell Leukemia, Sezary Syndrome, Mycosis Fungo Clinical Trial using A-dmDT390-bisFv(UCHT1)

Angimmune LLC - Recruiting 18 years or older.
- A Phase I/II Study of A-dmDT390-bisFv(UCHT1) Fusion Protein in Patients With Surface CD3+ Malignant T Cell Diseases.
A-dmDT390-bisFv(UCHT1)

Hurler Syndrome Clinical Trial using Laronidase

Masonic Cancer Center, University of Minnesota - Recruiting N/A to 14 years.
- Pilot Study of Administration of Intravenous Laronidase Following Allogeneic Transplantation for Hurler Syndrome.
Laronidase

Acute Lung Injury, Acute Respiratory Distress Syndrome, or Respir Clinical Trial using IV Ganciclovir; Placebo

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- A Randomized Double-Blind Placebo-Controlled Trial of Ganciclovir/Valganciclovir for Prevention of Cytomegalovirus Reactivation in Acute Injury of the Lung and Respiratory Failure (The GRAIL Study).
IV Ganciclovir; Placebo

Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Myeloid Leukemia, Mul Clinical Trial using Dasatinib; laboratory biomarker analysis

Barbara Ann Karmanos Cancer Institute - Recruiting 18 years or older.
- Phase I/II Study of Dasatinib in Recipients of Allogeneic Stem Cell Transplantation for Hematologic Malignancies..
Dasatinib; laboratory biomarker analysis

MonoMAC, Myelodysplastic Syndrome, or Immunodeficiency Clinical Trial using Reduced-Intensity Hematopoietic Stem Cell; Fludarabine; Total Body Irradiation (TBI); Filgrastim; Sirolimus; Tacrolimus; Ursodiol

National Institutes of Health Clinical Center (CC) - Recruiting 12 years to 60 years.
- Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for Patients With GATA2 Mutations.
Reduced-Intensity Hematopoietic Stem Cell; Fludarabine; Total Body Irradiation (TBI); Filgrastim; Sirolimus; Tacrolimus; Ursodiol

Cushing's Disease,, Acromegaly,, Neuroendocrine Tumors,, Pituitar Clinical Trial using Pasireotide

Novartis - Recruiting 18 years or older.
- An Open Label, Multi-center Pasireotide Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Pasireotide Study and Are Judged by the Investigator to Benefit From Continued Pasireotide Treatment.
Pasireotide

Obesity Hypoventilation Syndrome Clinical Trial using BiPAP - A40; BiPAP - ST

Association Nationale pour le Traitement à Domicile de l'Insuffisance Respiratoire - Recruiting 20 years to 80 years.
- Clinical Benefits and Tolerance to a New Ventilatory Mode in Patients With Obesity Hypoventilation Syndrome (OHS)..
BiPAP - A40; BiPAP - ST

Chest Pain, or Acute Coronary Syndrome Clinical Trial using Chest Pain Choice Decision Aid

Mayo Clinic - Recruiting 18 years or older.
- Shared Decision Making in the Emergency Department: The Chest Pain Choice Trial.
Chest Pain Choice Decision Aid

OAB (Overactive Bladder Syndrome and Detrusor Overactivity) Clinical Trial using Placebo (PBS-20% sucrose); hMaxi-K

Ion Channel Innovations - Recruiting 18 years or older.
- Phase 1 Double Blind, Placebo Controlled Study Assessing Safety and Activity Of 2 Escalating Doses of hMaxi-K Gene Transfer By Direct Injection Into the Bladder Wall In Female Subjects With OAB (Overactive Bladder Syndrome and Detrusor Overactivity).
Placebo (PBS-20% sucrose); hMaxi-K

Irritable Bowel Syndrome Clinical Trial using Standard protocol; Individualized protocol; Sham acupuncture/Placebo moxa

New York University School of Medicine - Recruiting 18 years to 70 years.
- Symptom Management for Irritable Bowel Syndrome.
Standard protocol; Individualized protocol; Sham acupuncture/Placebo moxa

Rapid Sequence Induction of General Anesthesia, Sellick Maneuver, Clinical Trial using effective sellick maneuver; sham sellick maneuver

Assistance Publique - Hôpitaux de Paris - Recruiting 18 years or older.
- Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial.
effective sellick maneuver; sham sellick maneuver

Metabolic Syndrome, or Insulin Resistance Clinical Trial using TA-65; Placebo

University of Connecticut - Recruiting 35 years to 70 years.
- The Effects of the Telomerase Activator TA-65 on Insulin Resistance, Inflammation, and Metabolic Syndrome.
TA-65; Placebo

Brain Disorders, Birth Defects, or Craniofacial Differences Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 80 years.
- Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders.

Myelofibrosis, Gaucher Disease, Pulmonary Fibrosis, Hermansky-Pud Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 80 years.
- Clinical and Basic Investigations Into Erdheim-Chester Disease.

HIV-1, HIV Infections, or Acquired Immunodeficiency Syndrome Clinical Trial using E/C/F/TAF; DRV; Pre-existing ARV regimen

Gilead Sciences - Recruiting 18 years or older.
- A Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults.
E/C/F/TAF; DRV; Pre-existing ARV regimen

Leukemia Clinical Trial using Eltrombopag; Hypomethylating Agent (HMA)

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase II Study of Eltrombopag With or Without Continuation of Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS).
Eltrombopag; Hypomethylating Agent (HMA)

Leukemia Clinical Trial using Vosaroxin; Decitabine

M.D. Anderson Cancer Center - Recruiting 60 years or older.
- A Phase I/II Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome.
Vosaroxin; Decitabine

Leukemia Clinical Trial using Ruxolitinib

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase I Study of Ruxolitinib for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS).
Ruxolitinib

Bipolar Disorder, Depression, Anxiety Disorders, Schizophrenia, T Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Brain Procurement for the Human Brain Collection Core.

Leukemia Clinical Trial using Clofarabine; Idarubicin; Cytarabine; Fludarabine

M.D. Anderson Cancer Center - Recruiting 18 years to 60 years.
- Phase I/II Randomized Study of Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia and High-Risk Myelodysplastic Syndrome.
Clofarabine; Idarubicin; Cytarabine; Fludarabine

Coronary Arteriosclerosis, or Non ST Segment Elevation Acute Coro Clinical Trial using OrbusNeich R stentT; Everolimus Eluting Stent (EES)

OrbusNeich - Recruiting 20 years or older.
- Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE): Assessment of a Novel DES Platform For Percutaneous Coronary Revascularization in Patients With Ischemic Coronary Disease and NSTEMI Acute Coronary Syndrome.
OrbusNeich R stentT; Everolimus Eluting Stent (EES)

Leukemia Clinical Trial using Cladribine; Cytarabine; Decitabine

M.D. Anderson Cancer Center - Recruiting 60 years or older.
- Phase II Study of Cladribine Plus Low Dose Cytarabine (LDAC) Induction Followed By Consolidation With Cladribine Plus LDAC Alternating With Decitabine in Patients With Untreated Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS).
Cladribine; Cytarabine; Decitabine

Idiopathic Nephrotic Syndrome Clinical Trial using DNA chip dedicated to the pharmacogenetic of steroids

Assistance Publique - H“pitaux de Paris - Recruiting 6 Months to 16 years.
- Factors of Steroid Dependency in Idiopathic Nephrotic Syndrome.
DNA chip dedicated to the pharmacogenetic of steroids

Cushing Syndrome Related to Cortisolic Adenoma Clinical Trial using analyze the role of glucocorticoid in AT distribution.

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Comparative Study of Subcutaneous and Visceral Adipose Tissue in Patients Affected by Cushing Syndrome Versus 2 Controls Population.
analyze the role of glucocorticoid in AT distribution.

HIV, Acquired Immunodeficiency Syndrome, or Cardiovascular Diseas Clinical Trial using Exercise Program; Control Group

University of Miami - Recruiting N/A to 25 years.
- Atherosclerotic Risk and Response to Exercise Intervention in HIV+ Children.
Exercise Program; Control Group

Respiratory Distress Syndrome, Adult Clinical Trial using ART Strategy; ARDSNet Strategy

Hospital do Coracao - Recruiting 18 years or older.
- Randomized Controlled Trial of Maximum Alveolar Recruitment Maneuver Plus Titrated PEEP Versus ARDSNet Strategy for ARDS.
ART Strategy; ARDSNet Strategy

Acute Respiratory Distress Syndrome (ARDS), or Mechanical Ventila Clinical Trial using Bronchoalveolar lavage (BAL) before day 2 , between days 5-7 and days 10-14 of evolution.

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Involvement of Fibrocytes in Repair Processes During Acute Respiratory Distress Syndrome (Validation Study-2).
Bronchoalveolar lavage (BAL) before day 2 , between days 5-7 and days 10-14 of evolution.

Sleep, Sleep Deprivation, or Insufficient Sleep Syndrome Clinical Trial using Sleep:wake 1; Sleep:wake 2

Brigham and Women's Hospital - Recruiting 18 years to 35 years.
- Sleep Duration Required to Restore Performance During Chronic Sleep Restriction.
Sleep:wake 1; Sleep:wake 2

Acute Myeloid Leukemia (AML), or Myelodysplastic Syndrome (MDS) Clinical Trial using Treosulfan

Center for International Blood and Marrow Transplant Research - Recruiting N/A to 21 years.
- A Phase II Study of Treosulfan/Fludarabine/Low Dose Total Body Irradiation as a Preparative Regimen for Children With AML/MDS Undergoing Allogeneic Hematopoietic Cell Transplantation.
Treosulfan

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using E/C/F/TAF

Gilead Sciences - Recruiting 12 years to 17 years.
- A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents.
E/C/F/TAF

Acute Myeloid Leukemia (AML), or Myelodysplastic Syndrome (MDS) Clinical Trial

Fred Hutchinson Cancer Research Center - Recruiting 18 years to 80 years.
- Feasibility and Outcomes of Allogeneic Hematopoietic Cell Transplantation (HCT) Compared to Conventional Chemotherapy for Older and Medically Infirm Patients Diagnosed With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes: A Prospective Observational Study.

Myelodysplastic Syndrome Clinical Trial using Oral Azacitidine; Placebo

Celgene Corporation - Recruiting 18 years or older.
- A Phase 3, Multicenter, Randomized, Double-blind Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo Plus Best Supportive Care in Subjects With Red Blood Cell Transfusion-dependent Anemia and Thrombocytopenia Due to IPSS Lower-risk Myelodysplastic Syndromes.
Oral Azacitidine; Placebo

HIV Infections Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Cohort Observational Study Evaluating Predictors, Incidence and Immunopathogenesis of Immune Reconstitution Syndrome (IRIS) in HIV-1 Infected Patients With CD4 Count Less Than or Equal to 100 Cells/microL Who Are Initiating Antiretroviral Therapy.

Primary Sjogren's Syndrome, or Myositis Clinical Trial using Exercise training

University of Sao Paulo - Recruiting 18 years to 80 years.
- Effects of Exercise Training in Primary Sjogren's Syndrome and Myositis.
Exercise training

Irritable Bowel Syndrome Clinical Trial using Glucose; Fructose; Fructans

University of Nottingham - Recruiting 18 years to 65 years.
- Fructose and Fructans and Irritable Bowel Syndrome: MRI Study of Underlying Mechanisms.
Glucose; Fructose; Fructans

Sj”gren's Syndrome Clinical Trial using Baminercept; Placebo

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 18 years to 75 years.
- A Randomized, Double-blind, Placebo-controlled Phase II Clinical Trial of Baminercept, a Lymphotoxin-beta Receptor Fusion Protein, for the Treatment of Primary Sj”gren's Syndrome (ASJ02).
Baminercept; Placebo

Myelodysplastic Syndromes (MDS), or Acute Myelogenous Leukemia (A Clinical Trial using low dose 5'-azacitidine

Memorial Sloan-Kettering Cancer Center - Recruiting 1 year to 75 years.
- A Single Arm Phase II Trial of Maintenance Low Dose 5'-Azacitidine Post T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Myelodysplastic Syndrome and Acute Myelogenous Leukemia With High Risk for Post-Transplant Relapse.
low dose 5'-azacitidine

Non ST Segment Elevation Acute Coronary Syndrome Clinical Trial using Ticagrelor; Clopidogrel

Catholic University of the Sacred Heart - Recruiting 50 years to 80 years.
- Effects of TIcaGREloR on Circulating Microparticles and Micro-RNAs in Patients With Non ST Elevation Acute Coronary Syndromes.
Ticagrelor; Clopidogrel

Down Syndrome Clinical Trial

Hoffmann-La Roche - Recruiting 12 years to 30 years.
- A Screening Protocol to Assess Adult and Adolescent Individuals With Down Syndrome for Eligibility to Participate in an Upcoming Study to Evaluate the Efficacy, Safety and Tolerability of RG1662 (Study BP27832).

Rett Syndrome Clinical Trial using Administration of a high dose of desipramine; Administration of a low dose of desipramine; Administration of a placebo

Assistance Publique Hopitaux De Marseille - Recruiting 4 years to 18 years.
- Pilot Study of the Effects of the Desipramine on the Neurovegetative Parameters of the Child With Rett Syndrome.
Administration of a high dose of desipramine; Administration of a low dose of desipramine; Administration of a placebo

Prader Willi Syndrome, or Hypoglycemia Clinical Trial using Infants with Prader-Willi Syndrome

University of Florida - Recruiting 2 Months to 12 Months.
- Hypoglycemia in Prader-Willi Syndrome: A Prospective Study.
Infants with Prader-Willi Syndrome

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myel Clinical Trial using fludarabine phosphate; cyclophosphamide; total-body irradiation; iodine I 131 monoclonal antibody BC8; allogeneic bone marrow transplantation; tacrolimus; mycophenolate mofetil

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- Hematopoietic Bone Marrow Transplantation for Patients With High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS) Using Related HLA-Mismatched Donors: A Trial Using Radiolabeled Anti-CD45 Antibody Combined With Immunosuppression Before and After Transplantation.
fludarabine phosphate; cyclophosphamide; total-body irradiation; iodine I 131 monoclonal antibody BC8; allogeneic bone marrow transplantation; tacrolimus; mycophenolate mofetil

Chronic Prostatitis/Chronic Pelvic Pain Syndrome, or Prostatitis Clinical Trial

Northwestern University - Recruiting 18 years or older.
- Chemokine Mechanisms in Chronic Pelvic Pain.

Obesity, Abdominal Clinical Trial using Urine sample; Blood sample; Assessment of sleep apnea syndrome; Electrocardiogram; Glucose tolerance test; Echocardiography; cardiac and abdominal magnetic resonance imaging; Ambulatory blood pressure monitoring; Echotracking; Pulse wave velocity; Composition of body mass by Dual x-ray absorptiometry

Central Hospital, Nancy, France - Recruiting 43 years to 72 years.
- Role of the Renin Angiotensin Aldosterone System and Remodeling of the Matrix Cardiac Extra Cellular in the Mechanisms of Transition to Heart Failure in Abdominal Obesity: Prospective Longitudinal Study R2C2 II.
Urine sample; Blood sample; Assessment of sleep apnea syndrome; Electrocardiogram; Glucose tolerance test; Echocardiography; cardiac and abdominal magnetic resonance imaging; Ambulatory blood pressure monitoring; Echotracking; Pulse wave velocity; Composition of body mass by Dual x-ray absorptiometry

Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Clinical Trial using standard follow-up care; medical chart review; quality-of-life assessment

Fred Hutchinson Cancer Research Center - Recruiting 18 years to 75 years.
- Phase 2 Study of Early Discharge and Outpatient Management of Adult Patients Following Intensive Chemotherapy for MDS and Non-APL AML.
standard follow-up care; medical chart review; quality-of-life assessment

Acute Coronary Syndrome Clinical Trial using Atorvastatin; Placebo

Hospital do Coracao - Recruiting 18 years or older.
- A Randomized, Multicenter Clinical Trial to Assess the Effect of Atorvastatin in Patients With Acute Coronary Syndrome and Intended Percutaneous Coronary Intervention.
Atorvastatin; Placebo

Intensive Care Unit, or Population at High Risk for ARDS Developm Clinical Trial using sRAGE

University Hospital, Clermont-Ferrand - Recruiting 18 years or older.
- Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients.
sRAGE

Acute Myocardial Infarction, or Artery; Deformity, Coronary (Acqu Clinical Trial using angioplasty

Umberto I Hospital, Frosinone Italy - Recruiting 18 years or older.
- Study of ABSORB Stent in Acute Coronary Syndrome.
angioplasty

Abusive Head Trauma, or Early Literacy Clinical Trial using Ready To Learn (RTL); All Babies Cry (ABC)

Women and Infants Hospital of Rhode Island - Recruiting 18 years or older.
- Can we Promote Early Literacy and Prevent Shaken Baby Syndrome in the Well Child Nursery?.A Randomized Controlled Study, The Early ABC Study..
Ready To Learn (RTL); All Babies Cry (ABC)

Job's Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES).

Myeldysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia, B Clinical Trial using Clofarabine; Lenalidomide

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Clofarabine Followed by Lenalidomide for Treatment of High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Clofarabine; Lenalidomide

Irritable Bowel Syndrome Clinical Trial using STW5 (Iberogast, BAY98-7411); Placebo

Bayer - Recruiting 18 years or older.
- A Double-blind, Randomised, Placebo-controlled Study on the Efficacy of Iberogastr (STW5) in Patients With Irritable Bowel Syndrome.
STW5 (Iberogast, BAY98-7411); Placebo

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Clinical Trial using tolvaptan

Otsuka Pharmaceutical Development & Commercialization, Inc. - Recruiting 18 years or older.
- A Phase 1b, Multicenter, Pilot, Randomized, Double-blind Trial to Determine the Pharmacokinetics and Pharmacodynamics of Orally Administered Tolvaptan 3.75, 7.5, and 15 mg Tablets in Subjects With Syndrome of Inappropriate Antidiuretic Hormone Secretion.
tolvaptan

Acquired Immune Deficiency Syndrome Clinical Trial using No intervention

Janssen Korea, Ltd., Korea - Recruiting 18 years or older.
- Regulatory Post Marketing Surveillance of Intelence Tablet.
No intervention

Primary Immune Deficiency Disorders, Common Variable Immunodefici Clinical Trial using Gammaplex (5%); Gammaplex 10

Bio Products Laboratory - Recruiting 2 years to 55 years.
- A Phase III, Multicenter, Open-label, Randomized, Two-Period, Crossover Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplexr 10 and Gammaplexr 5% in Primary Immunodeficiency Diseases.
Gammaplex (5%); Gammaplex 10

Nervous System Malformations, Arthropathy, Neurogenic, Urticaria, Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- A Long-Term Outcome Study With the IL-1 Receptor Antagonist Anakinra/Kineret in Patients With Neonatal Onset Multisystem Inflammatory Disease (NOMID/CINCA Syndrome) A Therapeutic Approach to Study the Pathogenesis of This Disease.

Neuroendocrine Tumors, Von Hippel-Lindau Syndrome, or Hippel-Lind Clinical Trial using 68Gallium DOTATATE; 111 In- Octreotide

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Evaluation of (68)Gallium- DOTATATE PET/CT for Detecting Primary and Metastatic Neuroendocrine Tumors.
68Gallium DOTATATE; 111 In- Octreotide

Autoimmune Disease, Lymphatic Disease, Lymphoproliferative Disord Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated With an Expansion of CD4-8-/TCR Alpha/Beta+ T Cells.

Hematologic Neoplasms, Neural Tube Defects, or Myeloproliferative Clinical Trial using therapeutic allogeneic lymphocytes; Sirolimus

National Institutes of Health Clinical Center (CC) - Recruiting 11 years to 90 years.
- Allogeneic HSCT Without Preparative Chemotherapy or With Low-Intensity Preparative Chemotherapy Using Sirolimus and Sirolimus-Generated Donor Th2 Cells for Therapy of Refractory Leukemia, Lymphoma, Myeloma, or Myelodysplastic Syndrome.
therapeutic allogeneic lymphocytes; Sirolimus

Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disea Clinical Trial using Cyclophosphamide; rituximab; Methotrexate; Sirolimus; Cyclosporine; Doxorubicin hydrochloride; Etoposide; Fludarabine phosphate; Prednisone; Vincristine sulfate; Cytarabine; Tacrolimus; Alemtuzumab

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 74 years.
- Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the Treatment of Leukemias, Lymphomas, and Pre-malignant Blood Disorders.
Cyclophosphamide; rituximab; Methotrexate; Sirolimus; Cyclosporine; Doxorubicin hydrochloride; Etoposide; Fludarabine phosphate; Prednisone; Vincristine sulfate; Cytarabine; Tacrolimus; Alemtuzumab

Movement Disorder, Tourette Syndrome, or Healthy Volunteer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 60 years.
- Investigation of Neurofeedback With Real-Time fMRI in Healthy Volunteers and Patients With Hyperkinetic Movement Disorders.

Sj(SqrRoot)(Delta)Gren s Syndrome, or Xerostomia Clinical Trial using Dexamethasone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Randomized Within-Subject, Double-Blind, Placebo-Controlled Study of Dexamethasone Irrigation of the Parotid Glands in Primary Sj(SqrRoot)(Delta)Gren's Syndrome Subjects.
Dexamethasone

MDS Clinical Trial using Darbepoetin alfa; Placebo

Amgen - Recruiting 18 years or older.
- A Multicenter, Randomised, Double-blind, Placebo-controlled Study of Darbepoetin Alfa for the Treatment of Anaemic Subjects With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS).
Darbepoetin alfa; Placebo

Mood Disorders, Premenstrual Syndrome, PMS, PMDD, Depression, or Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 50 years.
- 5HT1A and SERT Imaging During Pharmacologically Induced Hypogonadotropic Hypogonadism With and Without Estrogen and Progesterone Replacement.

Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberr Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Ocular Impact of X Chromosome Karyotype and Sex Hormones in Turner Syndrome.

Progressive Multifocal Leukoencephalopathy, Immune Reconstitution Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years or older.
- Natural History Study of Progressive Multifocal Leukoencephalopathy (PML).

Acute Coronary Syndrome Clinical Trial

AstraZeneca - Recruiting 18 years or older.
- Study on the Prevention of Cardiovascular Events by Antiplatelet Agents After Acute Coronary Syndrome.

Myelodysplastic Syndrome Clinical Trial using pracinostat; Placebo; Azacitidine

MEI Pharma, Inc. - Recruiting 18 years or older.
- A Phase 2 Randomized Double-Blind Placebo-Controlled Study of Pracinostat in Combination With Azacitidine in Patients With Previously Untreated International Prognostic Scoring System (IPSS) Intermediate Risk-2 or High-Risk Myelodysplastic Syndrome (MDS).
pracinostat; Placebo; Azacitidine

Myelodysplastic Syndromes, or Thrombocytopenia Clinical Trial using Eltrombopag

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS).
Eltrombopag

Immunologic Deficiency Syndrome, or Infection Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Detection and Characterization of Host Defense Defects.

Chronic Granulomatous Disease, Healthy, Immunologic Disease, Leuk Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 65 years.
- Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells.

Li-Fraumeni Syndrome Clinical Trial using Metformin

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome.
Metformin

Sjogren's Syndrome, or Xerostomia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 12 years to 80 years.
- Evaluation of Salivary Gland Dysfunction.

Albinism, Intestinal Disease, Kidney Disease, Myocardial Disease, Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 1 year to 80 years.
- Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome.

Polyostotic Fibrous Dysplasia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 1 year or older.
- Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome.

Chediak Higashi Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 1 Month or older.
- Investigations Into Chediak-Higashi Syndrome and Related Disorders.

Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- The Birt Hogg-Dube Syndrome: Identification of the Disease Gene and Characterization of the Predisposition of Renal Cancer.

Fatigue, Fibromyalgia, Pain, Complex Regional Pain Syndrome, or R Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Evaluation and Diagnosis of Potential Research Subjects With Pain and Fatigue Syndromes.

Hemangioblastoma, Hereditary Neoplastic Syndrome, Hippel Lindau D Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders.

Communication Disorder, Healthy, Stuttering, Tourette Syndrome, o Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 85 years.
- Multimodal Studies of Language Production and Comprehension in Normal Volunteers and Patients With Neurologically-Based Language Impairments.

Autoimmune Lymphoproliferative Syndrome, or Lymphoma Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 5 years or older.
- Use of Fluorodeoxyglucose Positron Emission Tomography With Computed Tomography for the Evaluation of Autoimmune Lymphoproliferative Syndrome Lymphadenopathy Suggestive of Lymphoma..

Immunologic Deficiency Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Molecular and Clinical Studies of Primary Immunodeficiency Diseases.

Developmental Delay Disorders, Chromosome Deletion, Mental Retard Clinical Trial using dTR Melatonin (NIH CC PDS); Phototherapy (Bright Light); Melatonin CR

National Institutes of Health Clinical Center (CC) - Recruiting 5 years to 45 years.
- A Phase One Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS).
dTR Melatonin (NIH CC PDS); Phototherapy (Bright Light); Melatonin CR

Tic Disorder, or Tourette Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- Understanding the Anatomy and Physiology of the Sensory Experience and Its Role in Generating Tics in Tourette Syndrome.

Rheumatoid Arthritis, Lupus Erythematosus, Systemic, or Sjogren's Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 24 years or older.
- Agricultural Health Study: Health Follow-up.

Myelodysplastic Syndrome (MDS), Hematologic Neoplasms, Hematologi Clinical Trial using Cord Blood Transplant

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications.
Cord Blood Transplant

Abnormalities, Craniopharyngioma, Cushing's Syndrome, Endocrine D Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 3 years to 70 years.
- A Clinical and Genetic Investigation of Pituitary Tumors and Related Hypothalmic Disorders.

Renal Cell Carcinoma, Graft-Versus-Host Disease, or Engraftment S Clinical Trial using Pentostatin; Sirolimus; Cyclophosphamide; Allogeneic Hematopoietic Stem Cell Transplant; Th2 Cell Transplantation; Th2 Cells in Allogeneic HSCT

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 75 years.
- Low Intensity Allogeneic Hematopoietic Stem Cell Transplantation Therapy of Metastatic Renal Cell Carcinoma Using Early and Multiple Donor Lymphocyte Infusions Consisting of Sirolimus-Generated Donor Th2 Cells.
Pentostatin; Sirolimus; Cyclophosphamide; Allogeneic Hematopoietic Stem Cell Transplant; Th2 Cell Transplantation; Th2 Cells in Allogeneic HSCT

PMDD, PMS, or Depression Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 50 years.
- The Treatment of Menstrually-Related Mood Disorders With the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron).

Craniosynostosis, or Muenke Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis).

Hematologic Disease, Lymphoma, Multiple Myeloma, Myelodysplastic Clinical Trial using Stem cell transplantation

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 80 years.
- Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients With Debilitating Hematologic Diseases.
Stem cell transplantation

Cushing Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- New Imaging Modalities in the Evaluation of Patients With Ectopic Cushing's Syndrome.

Pleuropulmonary Blastoma, Cystic Nephroma, Ovarian Sertoli-Leydig Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Dicer1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study.

Li-Fraumeni Syndrome, Neoplasms, or Tp53 Mutations Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 3 years or older.
- Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome.

Male Factor Infertility, Female Factor Infertility, or Turner Syn Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- The Clinical Study of Patients With Y Chromosome Variants.

Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain, or Fat Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Evaluation and Treatment Protocol for Potential Research Participants With Digestive Disorders.

Scapular Pain Clinical Trial using scapular exercise

Mae Fah Luang University Hospital - Recruiting 18 years to 50 years.
- Effects of Scapular Exercise on Patients With Scapulocostal Syndrome.
scapular exercise

Williams Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 5 years to 55 years.
- Defining the Brain Phenotype of Children With Williams Syndrome.

Adrenal Hyperplasia, Polycystic Ovarian Syndrome, Oligomenorrhea, Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 16 years to 29 years.
- Adrenal Hyperplasia Among Young Patients With Polycystic Ovarian Syndrome.

Hypereosinophilic Syndrome Clinical Trial using Corticosteroids

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Assessment of Glucocorticoid Responsiveness and Mechanisms of Resistance in Hypereosinophilic Syndromes.
Corticosteroids

Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficie Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 14 years or older.
- Characterization and Management of Patients With HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy.

KERATOCONJUNCTIVITIS SICCA, XEROSTOMIA, SICCA SYNDROME, or PRIMAR Clinical Trial using Laser 3R 790nm infrared Ga AIAs; Laser 3R 790 nm infrared GaAIAs

Federal University of Sao Paulo - Recruiting 18 years to 80 years.
- Low Level Laser Therapy For The Treatment Of Xerostomia In Primary Sjogren`s Syndrome.
Laser 3R 790nm infrared Ga AIAs; Laser 3R 790 nm infrared GaAIAs

Obesity, Stress, or Irritable Bowel Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 13 years to 45 years.
- Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain.

Hearing Impairment Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Non-Syndromic Hereditary Hearing Impairment - Gene Mapping: India/Pakistan Protocol.

Atopic Dermatitis, Netheron's Syndrome, Piebaldism, Hyper IgE Syn Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 80 years.
- Natural History of Atopic Dermatitis and Other Genetic/Congenital Diseases Associated With Allergic Inflammation.

HNPCC Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Living in Lynch Syndrome Limbo: Exploring the Meaning of Uncertain Genetic Test Results.

Autism Spectrum Disorder, Obsessive Compulsive Disorder, Pediatri Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Diagnosis and Treatment of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders.

Aplastic Anemia, Leukemia, Myelodysplastic Syndrome (MDS), or Lym Clinical Trial using Cord Blood Units

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients.
Cord Blood Units

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using Elvitegravir; RTV-boosted PI

Gilead Sciences - Recruiting N/A to 17 years.
- A Phase 2/3 Multicenter, Open-Label, Multicohort, Two-Part Study Evaluating the Pharmacokinetics (PK), Safety, and Antiviral Activity of Elvitegravir (EVG)Administered With a Background-Regimen (BR) Containing a Ritonavir-Boosted Protease Inhibitor (PI/r) in HIV-1 Infected, Antiretroviral Treatment-Experienced Pediatric Subjects.
Elvitegravir; RTV-boosted PI

Carcinoid Syndrome Clinical Trial using Telotristat etiprate tablets (250 mg); Placebo tablets

Lexicon Pharmaceuticals - Recruiting 18 years or older.
- A Phase 3, Randomized, Placebo-controlled, Parallel Group, Multicenter, Double-blind Study to Evaluate the Efficacy and Safety of Telotristat Etiprate (LX1606) in Patients With Carcinoid Syndrome Not Adequately Controlled by Somatostatin Analog (SSA) Therapy.
Telotristat etiprate tablets (250 mg); Placebo tablets

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adul Clinical Trial using pretargeted radioimmunotherapy; cyclosporine; mycophenolate mofetil; total-body irradiation; nonmyeloablative allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; fludarabine phosphate; pharmacological study

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- Hematopoietic Cell Transplantation for Patients With High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS) Using Radiolabeled DOTA-Biotin Pretargeted by BC8 Antibody-Streptavidin Conjugate.
pretargeted radioimmunotherapy; cyclosporine; mycophenolate mofetil; total-body irradiation; nonmyeloablative allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; fludarabine phosphate; pharmacological study

Body Composition, Beneficial, Paresis, or Impaired Glucose Tolera Clinical Trial using wt loss; Meal Pattern; meal pattern; even; skew

Purdue University - Recruiting 19 years to 50 years.
- Effects of Dietary Protein Patterning on wt Loss and Resistance Training-induced Changes in Body Comp, Skeletal Muscle, and Indices of Metabolic Syndrome.
wt loss; Meal Pattern; meal pattern; even; skew

Myelodysplastic Syndrome Clinical Trial using TL32711; 5-Azacitidine

TetraLogic Pharmaceuticals - Recruiting 18 years or older.
- A Phase 1b/2a, Open-label, Non-randomized Study of Birinapant in Combination With 5-azacitidine in Subjects With Myelodysplastic Syndrome Who Are Na‹ve, Refractory or Have Relapsed to 5-azacitidine Therapy.
TL32711; 5-Azacitidine

Myofascial Pain Syndrome Clinical Trial using Thai massage

Mae Fah Luang University Hospital - Recruiting 18 years to 40 years.
- Effects of Thai Massage on EMG.
Thai massage

Tourette Syndrome Clinical Trial using AZD5213 and placebo

AstraZeneca - Recruiting 12 years to 17 years.
- A 6-month, Multicenter, Randomized, Safety, Tolerability, Pharmacokinetic, and Preliminary Efficacy Study of AZD5213 in Adolescents With Tourette's Disorder.
AZD5213 and placebo

Myofascial Pain Syndrome Clinical Trial using Thai massage

Mae Fah Luang University Hospital - Recruiting 18 years to 40 years.
- Effects of Traditional Thai Massage on Pain and Pain Related Parameters in Patients With Upper Back Pain.
Thai massage

Acute Severe Respiratory Failure, or Acute Respiratory Distress S Clinical Trial

European Society of Intensive Care Medicine - Recruiting 16 years or older.
- A Multicentre, Prospective, Observational, 4-week Inception Cohort Study Being Carried Out by the Acute Respiratory Failure Section of ESICM.

Carcinoid Syndrome Clinical Trial using Telotristat etiprate tablets (250 mg)

Lexicon Pharmaceuticals - Recruiting 18 years or older.
- A Multicenter, Long-term Extension Study to Further Evaluate the Safety and Tolerability of Telotristat Etiprate (LX1606).
Telotristat etiprate tablets (250 mg)

Complex Regional Pain Syndrome (CRPS) Clinical Trial using Transcranial Magnetic Stimulation (TMS)

Stanford University - Recruiting 18 years or older.
- Transcranial Magnetic Stimulation for CRPS.
Transcranial Magnetic Stimulation (TMS)

Orbital Ischemic Syndrome, or Orbital Pseudotumor Clinical Trial

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Survey of Patients With Idiopathic Orbital Inflammation Syndrome (IOIS): Clinical, Morphological and Pathological Features and Treatment Outcomes.

Metabolic Syndrome X, Diastolic Dysfunction, or Insulin Resistanc Clinical Trial using Lifestyle Counseling; Metformin

Universidade do Porto - Recruiting 40 years to 64 years.
- Metformin in the Diastolic Dysfunction of Metabolic Syndrome: MET-DIME Trial.
Lifestyle Counseling; Metformin

Gastric Cancer With Metabolic Syndrome or Metabolic Disease Clinical Trial using subtotal gastrectomy with gastroduodenostomy; subtotal gastrectomy with Roux-en-Y gastrojejunostomy,; total gastrectomy with Rou-en-Y esophagojejunostomy

Yonsei University - Recruiting 20 years to 80 years.
- .
subtotal gastrectomy with gastroduodenostomy; subtotal gastrectomy with Roux-en-Y gastrojejunostomy,; total gastrectomy with Rou-en-Y esophagojejunostomy

Dysmetabolic Iron Overload Syndrome, or Metabolic Syndrome X Clinical Trial using dysmetabolic iron overload syndrome

University Hospital, Clermont-Ferrand - Recruiting 18 years or older.
- Impact of Dysmetabolic Iron Overload Syndrome on Polarization Capacity of Macrophages.
dysmetabolic iron overload syndrome

Acute Respiratory Distress Syndrome, Mechanical Ventilation, or T Clinical Trial using Rocuronium

University Medical Center Nijmegen - Recruiting 18 years or older.
- Reducing High Respiratory Drive to Facilitate Supported Ventilation in ARDS Patients: a Pilot Study.
Rocuronium

Hunter Syndrome Clinical Trial using idursulfase-IT; No IT treatment

Shire Human Genetic Therapies, Inc. - Recruiting N/A to 18 years.
- A Controlled, Randomized, Two-arm, Open-label, Assessor-blinded, Multicenter Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elapraser in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment.
idursulfase-IT; No IT treatment

Hypereosinophilic Syndrome Clinical Trial using mepolizumab

GlaxoSmithKline - Recruiting 12 years or older.
- A Compassionate Use Open-Label Study of Anti IL-5 (Mepolizumab) Treatment in Subjects With Hypereosinophilic Syndrome.
mepolizumab

Leukemia Clinical Trial using Quizartinib; Cytarabine; AZA

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase I/II Study of the Combination of Quizartinib (AC220) With 5-Azacytidine or Low-Dose Cytarabine for the Treatment of Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Phase I/Phase II.
Quizartinib; Cytarabine; AZA

Deep Vein Thrombosis, Venous Thrombosis, Postphlebitic Syndrome, Clinical Trial using Recombinant tissue plasminogen activator (rt-PA)

Washington University School of Medicine - Recruiting 16 years to 75 years.
- Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis--The ATTRACT Trial.
Recombinant tissue plasminogen activator (rt-PA)

Rett Syndrome Clinical Trial using NNZ-2566; Placebo

Neuren Pharmaceuticals Limited - Recruiting 16 years to 45 years.
- A Phase II Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Escalation Study of NNZ-2566 in Rett Syndrome.
NNZ-2566; Placebo

Churg-Strauss Syndrome Clinical Trial using Mepolizumab; Placebo

GlaxoSmithKline - Recruiting 18 years or older.
- A Double-blind, Randomised, Placebo-controlled Study to Investigate the Efficacy and Safety of Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis in Subjects Receiving Standard of Care Therapy.
Mepolizumab; Placebo

Acute Coronary Syndrome Clinical Trial

AstraZeneca - Recruiting N/A or older.
- A Retrospective Swedish Cohort Study on Health Outcomes, Life Expectancy, Resource Use and Costs in Patients With a History of Myocardial Infarction and Additional Risk Factors for Atherothrombosis.

Agammaglobulinemia, Common Variable Immunodeficiency, or Immunolo Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 85 years.
- Studies of Immune Regulation in Patients With Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes.

Acute Coronary Syndrome Clinical Trial using alirocumab SAR236553 (REGN727); placebo

Sanofi - Recruiting 40 years or older.
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome.
alirocumab SAR236553 (REGN727); placebo

Carpal Tunnel Syndrome Clinical Trial using mechanical traction; Care as usual

University of Tilburg - Recruiting 18 years to 80 years.
- Study of the Effectiveness of Mechanical Traction as a Non-Surgical Treatment for Carpal Tunnel Syndrome Compared to Care as Usual: a Randomized Controlled Trial.
mechanical traction; Care as usual

Acute Coronary Syndrome, or Adverse Reaction to Antiplatelet Agen Clinical Trial using Ticagrelor mashed pills; Ticagrelor integral pills

Careggi Hospital - Recruiting 18 years or older.
- Mojito Study (Mashed Or Just Integral Pill of TicagrelOr ? ).
Ticagrelor mashed pills; Ticagrelor integral pills

Metabolic Syndrome Clinical Trial using High Linoleic Safflower Oil

Ohio State University - Recruiting 50 years to 69 years.
- HEALTHY OILS FOR WOMEN: REDUCING VISCERAL ADIPOSE TISSUE IN WOMEN WITH METABOLIC SYNDROME (HOW STUDY).
High Linoleic Safflower Oil

Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leu Clinical Trial using ex vivo-expanded cord blood progenitor cell infusion; umbilical cord blood transplantation; double-unit umbilical cord blood transplantation; fludarabine phosphate; cyclophosphamide; total-body irradiation; cyclosporine; mycophenolate mofetil; laboratory biomarker analysis

Fred Hutchinson Cancer Research Center - Recruiting 6 Months to 45 years.
- Multi-center, Open-label Randomized Study of Single or Double Myeloablative Cord Blood Transplantation With or Without Infusion of Off-The-shelf ex Vivo Expanded Cryopreserved Cord Blood Progenitor Cells in Patients With Hematologic Malignancies.
ex vivo-expanded cord blood progenitor cell infusion; umbilical cord blood transplantation; double-unit umbilical cord blood transplantation; fludarabine phosphate; cyclophosphamide; total-body irradiation; cyclosporine; mycophenolate mofetil; laboratory biomarker analysis

Acute Coronary Syndrome Clinical Trial using Acetylsalicylic acid (Aspirin, BAY 81-8781)

Bayer - Recruiting 18 years or older.
- A Prospective, Randomized, Verum Controlled, Open Label, Parallel Group Multi-center Phase III Clinical Trial to Demonstrate the Superiority of 500 or 250 mg Aspirinr i.v. (BAY 81-8781) Treatment Versus 300 mg Aspirinr N Tablets p.o. (BAY e4465A) in Patients With Acute Coronary Syndrome, Measured by Time Dependent Thromboxane Inhibition.
Acetylsalicylic acid (Aspirin, BAY 81-8781)

Irritable Bowel Syndrome With Constipation (IBS-C) Clinical Trial using Placebo; Linaclotide

AstraZeneca - Recruiting 18 years or older.
- A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C).
Placebo; Linaclotide

Acute Coronary Syndrome Clinical Trial using Prasugrel; Clopidogrel

Klinikum der Universitaet Muenchen - Recruiting 18 years to 80 years.
- Platelet Function Guided Prasugrel Therapy in ACS Patients Undergoing PCI.
Prasugrel; Clopidogrel

Prader-Willi Syndrome, or Obesity Clinical Trial using Group 1; Group 2

University of Florida - Recruiting N/A to 60 years.
- Prader-Willi Syndrome and Early-onset Morbid Obesity Natural History Clinical Protocol.
Group 1; Group 2

Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Clinical Trial using clofarabine; cytarabine; busulfan; Plerixafor; cyclophosphamide; antithymocyte globulin (rabbit); stem cells; Tacrolimus; mycophenolate mofetil

St. Jude Children's Research Hospital - Recruiting N/A to 21 years.
- T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant.
clofarabine; cytarabine; busulfan; Plerixafor; cyclophosphamide; antithymocyte globulin (rabbit); stem cells; Tacrolimus; mycophenolate mofetil

Mycoses, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Bone Marro Clinical Trial using anti-thymocyte globulin; cyclosporine

Stanford University - Recruiting 18 years or older.
- A Phase II Study of Non-myeloablative Allogeneic Transplantation Using Total Lymphoid Irradiation (TLI) and Antithymocyte Globulin (ATG) In Patients With Cutaneous T Cell Lymphoma.
anti-thymocyte globulin; cyclosporine

Fragile X Syndrome Clinical Trial using NNZ-2566; Placebo

Neuren Pharmaceuticals Limited - Recruiting 14 years to 40 years.
- A Phase II Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Fixed-Dose Study of NNZ-2566 in Fragile X Syndrome.
NNZ-2566; Placebo

Acute Myeloid Leukemia Clinical Trial using PF-04449913; Low dose ARA-C (LDAC); Decitabine; Daunorubicin; Cytarabine; Pf-04449913

Pfizer - Recruiting 18 years or older.
- A Phase 1B/2 Study To Evaluate The Safety And Efficacy Of PF-04449913, An Oral Hedgehog Inhibitor, In Combination With Intensive Chemotherapy, Low Dose Ara-C Or Decitabine In Patients With Acute Myeloid Leukemia Or High Risk Myelodysplastic Syndrome.
PF-04449913; Low dose ARA-C (LDAC); Decitabine; Daunorubicin; Cytarabine; Pf-04449913

Eisenmenger Syndrome Clinical Trial using Macitentan 10 mg, oral tablet, to be taken once daily.; Matching placebo oral tablet, to be taken once daily.

Actelion - Recruiting 12 years to 70 years.
- A Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase 3 Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome..
Macitentan 10 mg, oral tablet, to be taken once daily.; Matching placebo oral tablet, to be taken once daily.

Acute Lung Injury, or Acute Respiratory Distress Syndrome Clinical Trial

Mayo Clinic - Recruiting 18 years or older.
- Identifying Patients at Risk of Developing Acute Lung Injury at the Time of Hospital Admission:Toward the Prevention of Acute Lung Injury (ALI).

Premenstrual Syndrome, or Mastodynia Clinical Trial using 20mg VAC BNO 1095 FCT; Placebo

Bionorica SE - Recruiting 18 years to 45 years.
- Prospective, Double-blind, Placebo-controlled, Parallel-group, Multi-centre Randomized Clinical Trial to Proof Efficacy and Safety of 20 mg (2 Tablets of 10 mg) VAC BNO 1095 FCT in Patients Suffering From Cyclic Mastodynia and PMS.
20mg VAC BNO 1095 FCT; Placebo

Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML); Clinical Trial using CliniMACS CD34+ Reagent System; Thiotepa; Cyclophosphamide; Alemtuzumab; Tacrolimus; Melphalan; Busulfan; Fludarabine

Columbia University - Recruiting N/A to 22 years.
- CD34+ Stem Cell Selection for Patients Receiving a Matched or Partially Matched Family or Unrelated Adult Donor Allogeneic Stem Cell Transplant for Malignant Disease.
CliniMACS CD34+ Reagent System; Thiotepa; Cyclophosphamide; Alemtuzumab; Tacrolimus; Melphalan; Busulfan; Fludarabine

Chronic Pelvic Pain Syndrome, or Bladder Pain Syndrome Clinical Trial using doxycycline; placebo

University Hospital Inselspital, Berne - Recruiting 18 years or older.
- Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective, Randomised,Placebo-controlled, Double-blind Study.
doxycycline; placebo

Precancerous Condition Clinical Trial using naproxen; placebo; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase Ib Biomarker Trial of Naproxen in Patients at Risk for DNA Mismatch Repair Deficient Colorectal Cancer.
naproxen; placebo; laboratory biomarker analysis

SLE Glomerulonephritis Syndrome, WHO Class V Clinical Trial using Acthar gel

Ohio State University - Recruiting 18 years or older.
- An Open Label Randomized Phase IV Study of the Safety and Efficacy of ACTHAR GEL in Patients With Membranous (Class V) Lupus Nephritis.
Acthar gel

Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Mycosi Clinical Trial using carfilzomib; romidepsin; laboratory biomarker analysis

Northwestern University - Recruiting 18 years or older.
- A Randomized Phase I Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma.
carfilzomib; romidepsin; laboratory biomarker analysis

Rett's Syndrome Clinical Trial using fingolimod (FTY720)

University Hospital, Basel, Switzerland - Recruiting 6 years or older.
- A Phase 1 Clinical Study to Assess Safety and Efficacy of Oral Fingolimod (FTY720) in Children With Rett Syndrome..
fingolimod (FTY720)

Metabolic Syndrome Clinical Trial using Niacin; Saturated meal; Monounsaturated meal; Polyunsaturated meal

National Research Council, Spain - Recruiting 18 years or older.
- OLIVE OIL ON NAMPT AND ITS RELATION WITH POSTPRANDIAL INFLAMMATION AND ATHEROSCLEROSIS IN THE SETTING OF METABOLIC SYNDROME. The OLNAMS Project.
Niacin; Saturated meal; Monounsaturated meal; Polyunsaturated meal

Compartment Syndrome Clinical Trial using Magellanr

Arteriocyte, Inc. - Recruiting 18 years to 65 years.
- Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield Trauma Study Protocol.
Magellanr

Adult Patients With Low- and Int-1-risk Myelodysplastic Syndrome Clinical Trial using Erythropoietin alpha; Deferasirox

Novartis - Recruiting 18 years or older.
- An Open-label, Phase II, Randomized, Pilot Study to Assess the Effect in Term of Erythroid Improvement of Deferasirox Combined With Erythropoietin Compared to Erythropoietin Alone in Patients With Low- and Int-1-risk Myelodysplastic Syndrome..
Erythropoietin alpha; Deferasirox

Metabolic Syndrome, or Coronary Artery Disease Clinical Trial

Ankara University - Recruiting 18 years to 80 years.
- Angiotensin Converting Enzyme Inhibitor Therapy and Periprocedural Myocardial Infarction in Patients With Metabolic Syndrome.

Respiratory Distress Syndrome Clinical Trial using ECALMIST; InSure

University of Manitoba - Recruiting 24 Weeks to 31 Weeks.
- ECALMIST (Early CPAP And Large Volume Minimal Invasive Surfactant Therapy) Versus InSurE (Intubate, Surfactant, Extubate) in Preterm Infants With Respiratory Distress Syndrome (RDS): Prospective Randomised Control Clinical Trial.
ECALMIST; InSure

Osteoarthritis, Cardiovascular Risk Factors, Cardiovascular Disea Clinical Trial using Cardiovascular risk factors diagnoses collection.; History of cardiovascular disease; Cardiovascular risk factors association

Hospital Parc Taul¡, Sabadell - Recruiting 50 years or older.
- Prevalence of Cardiovascular Risk Factors Between Patients With Knee or Hand Osteoarthritis.
Cardiovascular risk factors diagnoses collection.; History of cardiovascular disease; Cardiovascular risk factors association

Carpal Tunnel Syndrome Clinical Trial using Group One; Control Group Two

University of Missouri-Columbia - Recruiting N/A or older.
- Early Motion Following Carpal Tunnel Release, a Randomized Control Trial.
Group One; Control Group Two

Myelodysplastic Syndrome, or MDS Clinical Trial using pracinostat; Azacitidine; Decitabine

MEI Pharma, Inc. - Recruiting 18 years or older.
- A Phase II Simon Two-Stage Study of the Addition of Pracinostat to a Hypomethylating Agent (HMA) in Patients With Myelodysplastic Syndrome (MDS) Who Have Failed to Respond or Maintain a Response to the HMA Alone.
pracinostat; Azacitidine; Decitabine

Multiple Myeloma Clinical Trial

University of Arkansas - Recruiting 18 years or older.
- Engraftment Syndrome After Autologous Stem Cell Transplant: Retrospective Review in Patients With Multiple Myeloma.

Metabolic Syndrome X Clinical Trial using Ezetimibe; Placebo

Laval University - Recruiting 18 years to 60 years.
- Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study.
Ezetimibe; Placebo

Chronic Obstructive Pulmonary Disease, or Metabolic Syndrome Clinical Trial using Roflumilast; Placebo

Laval University - Recruiting 40 years to 80 years.
- Impact of Roflumilast on Visceral Adiposity and MetaBolic Profile in Chronic Obstructive Lung Disease: a Randomized and Controlled Trial: the RAMBO Trial..
Roflumilast; Placebo

Acute Coronary Syndrome Clinical Trial

Chattanooga-Hamilton County Hospital Authority - Recruiting 18 years or older.
- Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction.

Wegeners Granulomatosis, Microscopic Polyangiitis, Churg Strauss Clinical Trial

University of British Columbia - Recruiting N/A to 20 years.
- Chronic Childhood Vasculitis: Characterizing the Individual Rare Diseases to Improve Patient Outcomes.

Angelman Syndrome Clinical Trial using MINOCYCLINE; PLACEBO (for Minocycline)

Puerta de Hierro University Hospital - Recruiting 6 years to 30 years.
- Randomized Clinical Trial, Placebo Compared to Evaluate the Efficacy and Safety of Minocycline in Angelman Syndrome.
MINOCYCLINE; PLACEBO (for Minocycline)

Diastolic Heart Failure Clinical Trial using Perhexiline; Placebo

University of Aberdeen - Recruiting 16 years to 90 years.
- Randomised Double Blind Placebo Controlled Trial of Perhexiline in Heart Failure With Preserved Ejection Fraction Syndrome (HFpEF).
Perhexiline; Placebo

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adul Clinical Trial using iodine I 131 monoclonal antibody BC8; fludarabine phosphate; total-body irradiation; allogeneic hematopoietic stem cell transplantation; cyclosporine; mycophenolate mofetil; peripheral blood stem cell transplantation

Fred Hutchinson Cancer Research Center - Recruiting 16 years to 50 years.
- A Phase II Trial Combining Radiolabeled BC8 (Anti-CD45) Antibody With Fludarabine and Low Dose TBI Followed by Related or Unrelated PBSC Infusion and Post-Transplant Immunosuppression for Patients With Advanced AML or High Risk Myelodysplastic Syndrome.
iodine I 131 monoclonal antibody BC8; fludarabine phosphate; total-body irradiation; allogeneic hematopoietic stem cell transplantation; cyclosporine; mycophenolate mofetil; peripheral blood stem cell transplantation

Chest Pain, Acute Coronary Syndrome, Chest Pain Atypical Syndrome Clinical Trial

Wake Forest Baptist Health - Recruiting 21 years or older.
- The HEART Pathway: Bridging the Gap Between Operations, Research, and Education.

Hypoplastic Left Heart Syndrome Clinical Trial using autologous cell-based delivery

Mayo Clinic - Recruiting N/A to 18 Months.
- Phase I Safety Study of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Stage II Palliation of Hypoplastic Left Heart Syndrome.
autologous cell-based delivery

Burnout-Syndrome Clinical Trial using Diet and Lifestyle Counseling

Charite University, Berlin, Germany - Recruiting 18 years to 50 years.
- Diet and Lifestyle Modification in Mothers With Burnout-Syndrome: Ayurvedic Versus Conventional Standard Counseling - A Randomized Controlled Clinical Pilot Study.
Diet and Lifestyle Counseling

Neonatal Abstinence Syndrome Clinical Trial using sublingual buprenorphine; oral morphine

Thomas Jefferson University - Recruiting N/A or older.
- A Randomized, Active-Control, Double-Blind, Double-Dummy Clinical Trial Comparing Sublingual Buprenorphine And Morphine Solution For The Treatment Of Neonatal Opioid Abstinence Syndrome.
sublingual buprenorphine; oral morphine

Hypoplastic Left Heart Syndrome (HLHS) Clinical Trial using Collection of umbilical cord blood

Mayo Clinic - Recruiting N/A or older.
- Umbilical Cord Blood Collection and Processing for Cardiac Regeneration in Hypoplastic Left Heart Syndrome Patients.
Collection of umbilical cord blood

Neonatal Abstinence Syndrome Clinical Trial using oral morphine; sublingual buprenorphine

Thomas Jefferson University - Recruiting N/A or older.
- A Randomized, Open Label Clinical Trial of Buprenorphine in the Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines or Are Breastfeeding.
oral morphine; sublingual buprenorphine

Vasculitis Clinical Trial using Hematopoietic Stem Cell Transplant

Northwestern University - Recruiting 16 years to 60 years.
- High Dose Immune Suppression With Hematopoietic Stem Cell Support in Refractory Vasculitis, Necrotizing Vasculitis, Neurovascular Behcet's Disease, and Sjogren's Syndrome.
Hematopoietic Stem Cell Transplant

Hypoplastic Left Heart Syndrome Clinical Trial

Mayo Clinic - Recruiting N/A to 18 Months.
- A PROSPECTIVE STUDY OF PATIENTS WITH HYPOPLASTIC LEFT HEART SYNDROME FOLLOWING STAGE II SURGICAL PALLIATION.

Malformations, Multiple Abnormalies, or Polydactyly Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Genetic and Clinical Studies of Congenital Anomaly Syndromes.

Menkes Disease, Occipital Horn Syndrome, or Unexplained Copper De Clinical Trial using Copper Histidine

National Institutes of Health Clinical Center (CC) - Recruiting N/A to 65 years.
- Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency.
Copper Histidine

Focal Segmental Glomerulosclerosis, or Guillain-Barre Syndrome Clinical Trial using plasma exchange treatment

University Medical Centre Ljubljana - Recruiting 18 years or older.
- Regional Citrate Anticoagulation in Plasma Exchange Treatment.
plasma exchange treatment

Acquired Immune Deficiency Syndrome (AIDS), or HIV Infections Clinical Trial using ATV; DRV; Cobicistat; Background regimen

Gilead Sciences - Recruiting 3 Months to 17 years.
- A Phase 2/3, Multicenter, Open-label, Multicohort, Two-Part Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co), Administered With Background Regimen (BR) in HIV-1 Infected, Treatment-Experienced, Virologically Suppressed Pediatric Subjects.
ATV; DRV; Cobicistat; Background regimen

Rett Syndrome Clinical Trial using Glatiramer Acetate (Copaxoner)

Sheba Medical Center - Recruiting 6 years to 15 years.
- An Open Label, Exploratory Study to Investigate the Treatment Effect og Glatiramer Acetate (Copaxone r) on Girls Woth Rett Syndrome.
Glatiramer Acetate (Copaxoner)

Myelodysplastic Syndromes Clinical Trial using Lenalidomide

Washington University School of Medicine - Recruiting 18 years or older.
- Phase II Trial of High Dose Lenalidomide in Patients With Myelodysplastic Syndrome Refractory to Hypomethylating Agents.
Lenalidomide

Acute Coronary Syndrome, or Arterial Hypertension Clinical Trial using Renal denervation; Metoprolol; Lisinopril

Meshalkin Research Institute of Pathology of Circulation - Recruiting 18 years to 75 years.
- Renal Denervation in Patients After Acute Coronary Syndrome.
Renal denervation; Metoprolol; Lisinopril

Ischemic Stroke Clinical Trial using Qizhitongluo Capsule; Naoxintong Capsule; Aspirin Enteric-coated Tablets; the routine recovery training; placebo

China Academy of Chinese Medical Sciences - Recruiting 35 years to 80 years.
- Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke With Qi Deficiency and Blood Stasis Syndrome: a Multicenter, Randomized,Double-blind,Placebo- and Active-controlled Adaptive Study.
Qizhitongluo Capsule; Naoxintong Capsule; Aspirin Enteric-coated Tablets; the routine recovery training; placebo

Heterotaxy Syndrome Clinical Trial

Children's Hospital Boston - Recruiting N/A to 12 years.
- Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data.

Traumatic Brain Injury, or Post-traumatic Stress Disorder Clinical Trial

International Hyperbaric Medical Foundation - Recruiting 18 years to 65 years.
- Multicenter Observational Study of Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post-Concussion Syndrome (PCS) and/or TBI/Post-Traumatic Stress Disorder (PTSD).

Respiratory Failure, or Acute Respiratory Distress Syndrome Clinical Trial

Southeast University, China - Recruiting 18 years to 85 years.
- Southeast Univerity.

Gastrointestinal Fistula Clinical Trial

Jinling Hospital, China - Recruiting 18 years to 80 years.
- a Prospective Study to Investigate the Role of Enteral Nutrition in Nonthyroidal Illness Syndrome Among Fistula Patients.

Alagille Syndrome Clinical Trial using LUM001

Lumena Pharmaceuticals, Inc. - Recruiting 2 years or older.
- A Multicentre Extension Study to Evaluate the Long-Term Safety and Durability of the Therapeutic Effect of LUM001, an Apical Sodium-Dependent Bile Acid Transporter Inhibitor (ASBTi), in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome.
LUM001

Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrom Clinical Trial using Aldurazyme (laronidase)

Sanofi - Recruiting N/A or older.
- A Multicenter, Multinational, Open-Label Study of the Effects of Aldurazyme (Laronidase) Treatment on Lactation in Women With Mucopolysaccharidosis I (MPS I) and Their Breastfed Infants.
Aldurazyme (laronidase)

Myelodysplastic Syndrome Clinical Trial

Samsung Medical Center - Recruiting 18 years or older.
- Retrospective Study for Predictive Marker for Decitabine Treament in MDS Patients.

Parkinson's Syndrome Clinical Trial using NAV5001

Navidea Biopharmaceuticals - Recruiting 40 years or older.
- Evaluation of the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes.
NAV5001

Leukemia, Myelodysplastic Syndrome, or Lymphoma Clinical Trial using CliniMACS Fractionation system (Arm A); CliniMACS Fractionation system (Arm B)

Memorial Sloan-Kettering Cancer Center - Recruiting 2 years to 70 years.
- Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies.
CliniMACS Fractionation system (Arm A); CliniMACS Fractionation system (Arm B)

Parkinson's Syndrome Clinical Trial using NAV5001; DaTscan

Navidea Biopharmaceuticals - Recruiting 40 years or older.
- Evaluation of the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes.
NAV5001; DaTscan

Leukemia, Multiple Myeloma, Myelodysplastic Syndrome, or Non-Hodg Clinical Trial using Palifermin; Lupron; without the addition of palifermin or Lupron; peripheral blood stem cell transplantation

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years to 60 years.
- An Open Label Randomized Phase II Study of Palifermin With or Without Leuprolide Acetate Versus Control for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation.
Palifermin; Lupron; without the addition of palifermin or Lupron; peripheral blood stem cell transplantation

Restless Legs Syndrome Clinical Trial using Rotigotine

UCB, Inc. - Recruiting 13 years or older.
- An Open-Label, Long-Term, Follow-Up Study To Determine The Safety, Tolerability, and Efficacy of Rotigotine Transdermal System As Monotherapy in Adolescents With Restless Legs Syndrome.
Rotigotine

Restless Legs Syndrome Clinical Trial using Rotigotine

UCB, Inc. - Recruiting 13 years to 17 years.
- A Multicenter, Open-Label, 2-Group, Dose Escalation Study of Monotherapy Administration of Rotigotine in Pediatric Subjects With Idiopathic Restless Legs Syndrome.
Rotigotine

GVHD (Acute or Chronic), Acute Myeloid or Lymphoblastic Leukemia Clinical Trial using milatuzumab

Immunomedics, Inc. - Recruiting 18 years or older.
- A Phase I Study of Milatuzumab (hLL1) for Prevention of Acute Graft Versus Host Disease Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplant in Patients With Hematologic Malignancies.
milatuzumab

Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodyspla Clinical Trial using EPZ-5676

Epizyme, Inc. - Recruiting 18 years or older.
- A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving Translocation of the MLL Gene at 11q23 or Advanced Hematologic Malignancies.
EPZ-5676

Coronary Artery Desease,, Stable Angina,, or Acute Coronary Syndr Clinical Trial using Ticagrelor; Aspirin; Placebo - Ticagrelor; Placebo - Aspirin

Deutsches Herzzentrum Muenchen - Recruiting 18 years or older.
- A Randomized, Parallel Group, Double-Blind Study of Ticagrelor Compared With Aspirin for Prevention of Vascular Events in Patients Undergoing Coronary Artery Bypass Graft Operation TiCAB- Ticagrelor in CABG.
Ticagrelor; Aspirin; Placebo - Ticagrelor; Placebo - Aspirin

Clinically Isolated Syndrome, or Multiple Sclerosis Clinical Trial using tears and cerebrospinal fluid sampling

Lille Catholic University - Recruiting 18 years or older.
- Tear Analysis by Isoelectric Focusing in Clinically Isolated Syndrome as Multiple Sclerosis Criterion Among Patients With or Without Lesions at the Magnetic Resonance Imaging (Oligoclonal Profile of Tears).
tears and cerebrospinal fluid sampling

Menopausal Syndrome Clinical Trial using MELSMON; UNCNT

Unimed Pharmaceuticals - Recruiting 40 years or older.
- Study of Non-inferiority UNCNT Versus MELSMON in Female With Menopausal Syndrome: Randomized Confirmatory Clinical Trial.
MELSMON; UNCNT

Diabetes, Metabolic Syndrome, or Insulin Resistance Clinical Trial using pegvisomant

University of California, San Francisco - Recruiting 18 years to 80 years.
- Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Insulin Resistance But Without Diabetes.
pegvisomant

Human Immunodeficiency Virus (HIV), or Acquired Immune Deficiency Clinical Trial

Columbia University - Recruiting 1 Month to 12 years.
- Enhanced Surveillance and 2 Year Outcomes of Children Enrolled on Antiretroviral Therapy (ART) in Public Health Facilities in the Eastern Cape Province, South Africa.

Growth Disorder, Mental Retardation, or Multiple Abnormalies Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- The Phenotype and Etiology of Proteus Syndrome and Related Overgrowth Disorders.

Autosomal Recessive Polycystic Kidney Disease, Congenital Hepatic Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 6 Months to 80 years.
- Clinical and Molecular Investigations Into Ciliopathies.

Polycystic Ovary Syndrome, or Insulin Resistance Clinical Trial using acupuncture

The First Affiliated Hospital of Guangzhou Medical University - Recruiting 18 years to 49 years.
- The Effect of Acupuncture on Insulin Sensitivity in Insulin Resistance Women With Polycystic Ovary Syndrome A Pilot Study.
acupuncture

Meconium Aspiration Syndrome Clinical Trial using Lung lavage with surfactant; Bolus surfactant

Zekai Tahir Burak Maternity and Teaching Hospital - Recruiting N/A to 7 Days.
- Zekai Tahir Burak Maternity Teaching Hospital.
Lung lavage with surfactant; Bolus surfactant

Irritable Bowel Syndrome Clinical Trial using Mesalazine; Placebo

Karolinska Institutet - Recruiting 18 years to 70 years.
- Mesalazine Treatment in IBS, a Double-blind Placebo-controlled Phase II Intervention Study in Adult Patients.
Mesalazine; Placebo

Prematurity, or Respiratory Distress Syndrome, Infant Clinical Trial using Sudden wean of nasal CPAP; Gradual wean of nasal CPAP

Aarhus University Hospital - Recruiting N/A to 6 Months.
- Weaning of Nasal Continuous Positive Airway Pressure in Infants Born With a Gestational Age Under 32 Weeks: a Randomized Controlled Multicenter Trial.
Sudden wean of nasal CPAP; Gradual wean of nasal CPAP

Systemic Capillary Leak Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 16 years to 80 years.
- Studies in the Pathogenesis of Systemic Capillary Leak Syndrome.

Hypercortisolism, or Cushing Syndrome Clinical Trial using Adrenalectomy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Randomized Control Trial of Adrenalectomy Versus Observation for Subclinical Hypercortisolism.
Adrenalectomy

Acute Coronary Syndrome, or Myocardial Infarction Clinical Trial

Virginia Commonwealth University - Recruiting 18 years or older.
- Point of Care (POC) Biomarkers of Ischemia.

Atypical Hemolytic-Uremic Syndrome Clinical Trial

Alexion Pharmaceuticals - Recruiting N/A or older.
- An Observational, Non-Interventional, Multi-Center, Multi-National Study of Patients With aTypical Hemolytic-Uremic Syndrome (aHUS Registry).

Complication of Transplanted Lung Clinical Trial using Aztreonam Lysine for Inhalation (AZLI); Status Post Lung Transplant

Duke University - Recruiting 18 years or older.
- Aztreonam Lysine for Inhalation (AZLI) in the Treatment of Early Bronchiolitis Obliterans Syndrome (BOS) After Lung Transplantation.
Aztreonam Lysine for Inhalation (AZLI); Status Post Lung Transplant

Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, or Myelod Clinical Trial using Lupron; 18F FLT; Cyclophosphamide; Methotrexate; Tacrolimus; Total Body Irradiation

National Institutes of Health Clinical Center (CC) - Recruiting 8 years to 60 years.
- Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults With Molecular Imaging Evaluation.
Lupron; 18F FLT; Cyclophosphamide; Methotrexate; Tacrolimus; Total Body Irradiation

Irritable Bowel Syndrome Clinical Trial

University of Nottingham - Recruiting 18 years to 75 years.
- Optimising Measurement of Small and Large Bowel Transit During MRI Scanning and Characterising IBS Subtypes and Their Response to Stress Using MRI (Study 1).

Down Syndrome, or Fetal Aneuploidy Clinical Trial

Sequenom, Inc. - Recruiting 18 years or older.
- Collection of Whole Blood Specimens From Pregnant Women at Increased Risk of Fetal Chromosomal Aneuploidy for Use in Development of the SEQureDx Trisomy 21 Test in the Detection of the Relative Quantity of Chromosome 21 Circulating Cell-Free DNA Extracted From Maternal Plasma.

Klinefelter Syndrome Clinical Trial using Seminal analyses and testicular biopsy

Hospices Civils de Lyon - Recruiting 15 years to 55 years.
- Fertility Preservation in Cases of Spermatogenesis Failure : Prospective Study for Klinefelter Syndrome With Non-mosaic Karyotype (47, XXY, Homogeneous).
Seminal analyses and testicular biopsy

Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Clinical Trial using cytarabine; daunorubicin hydrochloride; etoposide; pomalidomide; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years to 65 years.
- A Phase I Study of Pomalidomide Given at the Time of Lymphocyte Recovery Following Induction Timed Sequential Chemotherapy With Cytarabine, Daunorubicin and Etoposide (AcDVP16) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) and High-Risk MDS.
cytarabine; daunorubicin hydrochloride; etoposide; pomalidomide; laboratory biomarker analysis

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myel Clinical Trial using lenalidomide; laboratory biomarker analysis

Albert Einstein College of Medicine of Yeshiva University - Recruiting 60 years to 75 years.
- A Phase I/II Study of Lenalidomide Maintenance After Autologous Stem Cell Transplant for Elderly Patients With Acute Myeloid Leukemia (AML).
lenalidomide; laboratory biomarker analysis

Acute Coronary Syndrome Clinical Trial

Hopital LariboisiŠre - Recruiting 18 years or older.
- Persistent Platelet Reactivity in Acute Coronary Syndrome.

Immune Disorders, Chronic Granulomatous Disease, Genetic Immunolo Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Screening Protocol for Detection and Characterization of Infections and Infection Susceptibility.

Williams Beuren Syndrome Clinical Trial using Minoxidil; Placebo

Hospices Civils de Lyon - Recruiting 6 years to 18 years.
- The Efficacy of Minoxidil in Children With Williams-Beuren Syndrome: a Randomized Clinical Trial..
Minoxidil; Placebo

Cushing's Syndrome, Hereditary Neoplastic Syndrome, Lentigo, Neop Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 3 years or older.
- Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions.

Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leu Clinical Trial using fludarabine phosphate; cyclosporine; sirolimus; mycophenolate mofetil; allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; total-body irradiation

Fred Hutchinson Cancer Research Center - Recruiting N/A or older.
- A Randomized Phase III Study to Determine the Most Promising Postgrafting Immunosuppression for Prevention of Acute GVHD After Unrelated Donor Hematopoietic Cell Transplantation Using Nonmyeloablative Conditioning for Patients With Hematologic Malignancies: A Multi-Center Trial.
fludarabine phosphate; cyclosporine; sirolimus; mycophenolate mofetil; allogeneic hematopoietic stem cell transplantation; peripheral blood stem cell transplantation; total-body irradiation

Retinitis Pigmentosa Syndromic, Congenital Deafness, Usher Syndro Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years or older.
- Natural History and Genetic Studies of Usher Syndrome.

Interstitial Cystitis, or Bladder Pain Syndrome Clinical Trial using AQX-1125

Aquinox Pharmaceuticals, Inc. - Recruiting 18 years to 75 years.
- A Phase 2 Study to Evaluate the Efficacy and Safety of AQX-1125 in Subjects With Interstitial Cystitis/Bladder Pain Syndrome Mediated by the Src Homology-2-domain-containing Inositol 5' Phosphatase [SHIP1] Pathway.
AQX-1125

Atypical Mycobacterium Infections, Cystic Fibrosis, or Job's Synd Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections.

Fragile-X Syndrome Clinical Trial

Novartis - Recruiting N/A or older.
- EXPLAIN - FragilE X Registry: An exPlorative Longitudinal Study for chAracterIzation, Treatment Pathways and patieNt-related Outcomes.

Nephrotic Syndrome, Proteinuria, Autoimmune Disease, Glomerular D Clinical Trial using Rituximab Infusion; Oral Cyclosporine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy.
Rituximab Infusion; Oral Cyclosporine

Fragile X Syndrome Clinical Trial using AFQ056

Novartis - Recruiting 18 years to 46 years.
- An Open-label Study to Evaluate the Long-term Safety, Tolerability and Efficacy of AFQ056 in Adult Patients With Fragile X Syndrome.
AFQ056

Immunologic Deficiency Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Molecular Basis of Primary Immunodeficiencies.

Down Syndrome, or Obstructive Sleep Apnea Syndrome Clinical Trial using Continuous positive airway pressure; Sham or placebo continuous positive airway pressure

Children's Hospital of Philadelphia - Recruiting 8 years to 20 years.
- Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome.
Continuous positive airway pressure; Sham or placebo continuous positive airway pressure

Obstructive Sleep Apnea of Adult, Insomnia, Circadian Rhythm Slee Clinical Trial using CONV care for the diagnosis and treatment of sleep disorders; PCCM for the diagnosis and treatment of sleep disorders

Stanford University - Recruiting 18 years or older.
- Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study (SMART DOCS).
CONV care for the diagnosis and treatment of sleep disorders; PCCM for the diagnosis and treatment of sleep disorders

Chromosome Abnormalities, or Smith Magenis Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS).

MDS (Myelodysplastic Syndrome), Myeloproliferative Disorder, Lymp Clinical Trial using Graft Manipulation (CD34+ Selection)

National Institutes of Health Clinical Center (CC) - Recruiting 2 years to 80 years.
- Peripheral Blood Stem Cell Allotransplantation For Hematological Malignancies Using Ex Vivo CD34 Selection - a Platform For Adoptive Cellular Therapies.
Graft Manipulation (CD34+ Selection)

Abdominal Obesity Metabolic Syndrome, Insulin Resistance, or Hype Clinical Trial using Eplerenone; Placebo

Maastricht University Medical Center - Recruiting 40 years to 65 years.
- Effects of Aldosterone Antagonism on Insulin-mediated Microvascular Function in Subjects With the Metabolic Syndrome.
Eplerenone; Placebo

Emotions, Memory Deficits, or Post-traumatic Syndrome Clinical Trial using Trauma-focused cognitive behavioral therapy

Stanford University - Recruiting 12 years to 17 years.
- Biomarkers of Clinical Response to Cognitive Treatment of PTSD in Youth.
Trauma-focused cognitive behavioral therapy

Hypogonadotropic Hypogonadism, Kallmann Syndrome, or GnRH Deficie Clinical Trial using kisspeptin 112-121; GnRH

Massachusetts General Hospital - Recruiting 18 years to 65 years.
- Administration of Kisspeptin 112-121 to Subjects With Hypogonadotropic Hypogonadism.
kisspeptin 112-121; GnRH

Hypogonadotropic Hypogonadism, Healthy Postmenopausal Women, Prim Clinical Trial using kisspeptin 112-121; GnRH

Massachusetts General Hospital - Recruiting 21 years to 60 years.
- Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling.
kisspeptin 112-121; GnRH

Glucose Transporter Type-1 Deficiency Syndrome (Glut1 DS) Clinical Trial using Triheptanoin

Cook Children's Health Care System - Recruiting 1 year to 18 years.
- An Open-Label Trial of Triheptanoin in Patients With Glucose Transporter Type-1 Deficiency Syndrome (GLUT1 DS).
Triheptanoin

Delayed Puberty, Kallmann Syndrome, Hypogonadotropic Hypogonadism Clinical Trial using kisspeptin 112-121

Massachusetts General Hospital - Recruiting 13 years to 17 years.
- Kisspeptin in the Evaluation of Delayed Puberty.
kisspeptin 112-121

Carpal Tunnel Syndrome Clinical Trial using Ultrasound; methylprednisolone

Universit‚ de Sherbrooke - Recruiting 18 years to 65 years.
- Syndrome du Tunnel Carpien - Essai Clinique randomis‚ ‚valuant l'efficacit‚ de l'Utilisation de l'‚chographie Lors de l'Infiltration de corticost‚ro‹des.
Ultrasound; methylprednisolone

Toxic Epidermal Necrolysis, or Stevens-Johnson Syndrome Clinical Trial using Palifermin

Yale University - Recruiting 18 years or older.
- Palifermin Treatment of Toxic Epidermal Necrolysis.
Palifermin

Concussion, Post-concussion Syndrome, Mild Traumatic Brain Injury Clinical Trial using Aerobic Training Intervention; Stretching Intervention

Children's Hospital Medical Center, Cincinnati - Recruiting 12 years to 17 years.
- Aerobic Training for Management of Post-Concussion Syndrome in Adolescents.
Aerobic Training Intervention; Stretching Intervention

Coronary Heart Disease, Unstable Angina, or Blood Stasis Syndrome Clinical Trial using Xuesaitong soft capsule; Xuesaitong soft capsule Placebo

Guang'an Men Hospital - Recruiting 30 years to 75 years.
- The Analysis of Blood Stasis Syndromeand of Coronary Heart Disease Related MicroRNA Genomics and Target Gene Regulatory Networks.
Xuesaitong soft capsule; Xuesaitong soft capsule Placebo

Acquired Immunodeficiency Syndrome, or HIV Infections Clinical Trial using EVG/COBI/FTC/TDF

Gilead Sciences - Recruiting 12 years to 17 years.
- A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/ Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents.
EVG/COBI/FTC/TDF

Bladder Pain Syndrome, Pentosan Polysulfate, or Hydrodistension Clinical Trial

Samsung Medical Center - Recruiting N/A or older.
- The Efficacy of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy in Patients With Bladder Pain Syndrome.

Proteinuria, or Idiopathic Membranous Nephropathy Clinical Trial using Repository Corticotropin Injection; Placebo

Questcor Pharmaceuticals, Inc. - Recruiting 18 years or older.
- A Randomized, Placebo-Controlled, Parallel-Group, Double-Blind Study of H.P. Acthar Gel (Acthar) in Treatment-Resistant Subjects With Persistent Proteinuria and Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy (iMN).
Repository Corticotropin Injection; Placebo

Metabolic Syndrome Clinical Trial using glucose and insulin testing

Vanderbilt University - Recruiting 18 years to 70 years.
- Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism.
glucose and insulin testing

Myelodysplastic Syndrome, or Leukemia Clinical Trial using Cord Blood Infusion; Busulfan; Fludarabine; Rituximab; ATG; Cyclophosphamide; Clofarabine; Total Body Irradiation (TBI); Melphalan; Tacrolimus; Mycophenolate Mofetil; G-CSF

M.D. Anderson Cancer Center - Recruiting 1 year to 80 years.
- Cord Blood Expansion on Mesenchymal Stem Cells.
Cord Blood Infusion; Busulfan; Fludarabine; Rituximab; ATG; Cyclophosphamide; Clofarabine; Total Body Irradiation (TBI); Melphalan; Tacrolimus; Mycophenolate Mofetil; G-CSF

Heterozygous Carriers of Gitelman Syndrome Clinical Trial using Blood sample; Urine sample; Blood pressure

Assistance Publique - H“pitaux de Paris - Recruiting 18 years to 75 years.
- Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter.
Blood sample; Urine sample; Blood pressure

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adul Clinical Trial using DEC-205/NY-ESO-1 fusion protein CDX-1401; poly ICLC; decitabine; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Phase I Study of DEC205mAb-NY ESO 1 Fusion Protein (CDX-1401) Given With Adjuvant polyICLC in Conjunction With 5-Aza-2'Deoxycytidine (Decitabine) in Patients With MDS or Low Blast Count AML.
DEC-205/NY-ESO-1 fusion protein CDX-1401; poly ICLC; decitabine; laboratory biomarker analysis

Metabolic Syndrome, Cardiovascular Disease, Atherosclerosis, or O Clinical Trial using My Everyday Health

Baptist Health South Florida - Recruiting 18 years or older.
- Baptist Employee Healthy Heart Study (BEHHS) - A Novel Web-based Approach to Reduce Cardiovascular Disease Risk in a Diverse Employee Population With Metabolic Syndrome Via Diet and Lifestyle Change.
My Everyday Health

Persian Gulf War Syndrome in Veteran Clinical Trial using Hubbard detoxification program

University at Albany - Recruiting N/A or older.
- Pilot Study of Application of the Hubbard Detoxification Program to Veterans With Gulf War Illness.
Hubbard detoxification program

Cushing Syndrome Clinical Trial using F-DOPA PET Scan; Mifepristone; Ga-DOTATATE; Octreoscan; CT, MRI

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients With Ectopic Cushing Syndrome.
F-DOPA PET Scan; Mifepristone; Ga-DOTATATE; Octreoscan; CT, MRI

Interstitial Cystitis Clinical Trial

Asan Medical Center - Recruiting 20 years or older.
- Experimental Study of Biomarker in Patient With Interstitial Cystitis/Painful Bladder.

Interstitial Cystitis Clinical Trial using Hyaluronic acid/chondroitin sulfate

Asan Medical Center - Recruiting 20 years or older.
- The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome..
Hyaluronic acid/chondroitin sulfate

Acute Myeloid Leukemia, Infantile Leukemia (Both AML and ALL), My Clinical Trial using Sorafenib; Cytarabine; Clofarabine

St. Jude Children's Research Hospital - Recruiting N/A to 31 years.
- A Pilot Pharmacokinetic, Pharmacodynamic and Feasibility Study of Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies.
Sorafenib; Cytarabine; Clofarabine

Traumatic Brain Injury, Cerebrovascular Accident (CVA), or Acquir Clinical Trial using Conventional rehabilitation.; Novel rehabilitation approach

Baycrest - Recruiting 18 years or older.
- Managing the Dysexecutive Syndrome Following Traumatic Brain Injury: An Ecologically Valid Rehabilitation Approach.
Conventional rehabilitation.; Novel rehabilitation approach