53 results found.

Epilepsy, or Pregnancy Clinical Trial

Emory University - Recruiting 14 years to 45 years.
- Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs.

Epilepsy Clinical Trial using USL261; Placebo

Upsher-Smith Laboratories - Recruiting 14 years to 65 years.
- A Randomized, Double-blind, Placebo-controlled Study of the Safety and Efficacy of Intranasal Midazolam (USL261) in the Outpatient Treatment of Subjects With Seizure Clusters. ARTEMIS-1: Acute Rescue Therapy in Epilepsy With Midazolam Intranasal Spray-1.
USL261; Placebo

Epilepsy, or Partial-onset Seizures Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 16 years to 70 years.
- A Multi-center, Open-label, Uncontrolled, Long-term, Extension Study to Evaluate the Safety and Efficacy of Lacosamide as Adjunctive Therapy in Japanese and Chinese Adults With Partial-onset Seizures With or Without Secondary Generalization.
Lacosamide

Epilepsy Clinical Trial using USL261

Upsher-Smith Laboratories - Recruiting 14 years to 66 years.
- An Open-Label Safety Study of USL261 in the Outpatient Treatment of Subjects With Seizure Clusters.
USL261

Epilepsy, or Partial Seizures Clinical Trial using Levetiracetam; Carbamazepine

UCB, Inc. - Recruiting 16 years or older.
- An Open-label, Randomized, Parallel-group, Active-controlled Study Comparing the Efficacy and Safety of Levetiracetam to Carbamazepine Used as Monotherapy in Subjects Newly or Recently Diagnosed as Epilepsy and Partial-onset Seizures.
Levetiracetam; Carbamazepine

Epilepsy Clinical Trial using Lacosamide; Placebo

UCB, Inc. - Recruiting 4 years to 17 years.
- A Multicenter, Double Blind, Randomized, Placebo Controlled, Parallel Group Study to Investigate the Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects With Epilepsy ò4 Years to <17 Years of Age With Partial Onset Seizures.
Lacosamide; Placebo

Epilepsy Clinical Trial using Levetiracetam; Topiramate

UCB, Inc. - Recruiting 16 years to 80 years.
- A Randomized, Open-label, Parallel Group, Multi-center, Comparative, Phase IV Trial of Levetiracetam (LEV) Versus Topiramate (TPM) as Adjunctive Therapy to Evaluate Efficacy and Safety in Adult Subjects With Refractory Partial Onset Seizures.
Levetiracetam; Topiramate

Epilepsy Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 1 Month to 18 years.
- A MULTI-CENTER, OPEN-LABEL, EXPLORATORY STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF LACOSAMIDE AS ADJUNCTIVE THERAPY IN SUBJECTS ò1 MONTH TO <18 YEARS WITH EPILEPSY SYNDROMES ASSOCIATED WITH GENERALIZED SEIZURES..
Lacosamide

Epilepsy, Partial Seizures Clinical Trial using Pregabalin add-on therapy

Pfizer - Recruiting 4 years to 16 years.
- A Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study of the Efficacy and Safety of Pregabalin As Adjunctive Therapy in Children 4 -16 Years of Age With Partial Onset Seizures.
Pregabalin add-on therapy

Epilepsy, Partial Seizures Clinical Trial using Pregabalin

Pfizer - Recruiting 1 Month to 65 years.
- A 12-Month Open-Label Study To Evaluate The Safety And Tolerability Of Pregabalin As Adjunctive Therapy In Children 1 Month To 16 Years Of Age With Partial Onset Seizures And Child And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures.
Pregabalin

Generalized Tonic Clonic Seizures Clinical Trial using Pregabalin Dose Level 1; Pregabalin Dose Level 2; Placebo

Pfizer - Recruiting 5 years to 65 years.
- A Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center Trial of Pregabalin As Adjunctive Therapy in Pediatric and Adult Subjects With Primary Generalized Tonic Clonic Seizures - Protocol A0081105.
Pregabalin Dose Level 1; Pregabalin Dose Level 2; Placebo

Focal Epilepsy Clinical Trial using Lacosamide

Lawson Health Research Institute - Recruiting 18 years to 65 years.
- Lacosamide IV and EEG/EKG (LIVE) Study.
Lacosamide

Epilepsy, or Monotherapy Clinical Trial using Lacosamide; Carbamazepine-Controlled Release

UCB, Inc. - Recruiting 16 years or older.
- A Multicenter, Double-blind, Double-dummy, Randomized, Positive- Controlled Study Comparing the Efficacy and Safety of Lacosamide (200 to 600 mg/Day) to Controlled Release Carbamazepine (400 to 1200 mg/Day), Used as Monotherapy in Subjects (ò 16 Years) Newly or Recently Diagnosed With Epilepsy and Experiencing Partial-onset or Generalized Tonic-clonic Seizures..
Lacosamide; Carbamazepine-Controlled Release

Epilepsy, or Monotherapy Clinical Trial using Lacosamide; Carbamazepine-Controlled Release (CBZ-CR)

UCB, Inc. - Recruiting N/A or older.
- A Multicenter, Double-blind, Double-dummy, Follow up Study Evaluating the Long-term Safety of Lacosamide in Comparison With Controlled-release Carbamazepine Used as Monotherapy in Subjects With Partial-onset or Generalized Tonic-clonic Seizures ò16 Years of Age Coming From the SP0993 Study..
Lacosamide; Carbamazepine-Controlled Release (CBZ-CR)

Epilepsy, or Temporal Lobe Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Assessment of [11C]DPA-713 in Temporal Lobe Epilepsy.

Seizures, Epilepsy, Partial Epilepsy, or Depression Clinical Trial using Buspirone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- A Phase Two Clinical Trial of Buspirone Therapy in Localization-Related Epilepsy.
Buspirone

Epilepsy Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 60 years.
- Imaging Serotoninergic Neurotransmission in Epilepsy.

Epilepsy, Epilepsy, Temporal Lobe, or Partial Epilepsy Clinical Trial using Surgery

National Institutes of Health Clinical Center (CC) - Recruiting 8 years or older.
- Surgery as a Treatment for Medically Intractable Epilepsy.
Surgery

Epilepsy Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years or older.
- Evaluation and Treatment of Patients With Epilepsy.

Epilepsies, Partial Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 60 years.
- Positron Emission Tomography Measurement of Neuroinflammation and P-glycoprotein in Localization-Related Epilepsy.

Glioblastoma Multiforme Clinical Trial using ketogenic diet

Mid-Atlantic Epilepsy and Sleep Center, LLC - Recruiting 18 years to 65 years.
- Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study.
ketogenic diet

Focal Epilepsy With and Without Secondary Generalization Clinical Trial

UCB, Inc. - Recruiting 18 years or older.
- A Non-interventional, Observational Study Evaluating Changes in Drug Load and Seizure Frequency Using Vimpat (Lacosamide) in Daily Clinical Practice in Combination Therapy With Sodium Channel Blocking Anti-epileptic Drugs (AEDs) or Non Sodium Channel Blocking AEDs.

Autistic Disorder, Seizures, or Irritability Clinical Trial using N-Acetyl Cysteine (NAC)

Nationwide Children's Hospital - Recruiting 6 years to 21 years.
- Pilot Study of N-acetyl Cysteine for Refractory Generalized Epilepsy in Children With Autism.
N-Acetyl Cysteine (NAC)

Epilepsy Clinical Trial using Muscimol

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Trial of Intracerebral Infusion in Patients With Medically Intractable Epilepsy.
Muscimol

Drug Resistant Partial Onset Seizure Clinical Trial using ganaxolone; Placebo

Marinus Pharmaceuticals - Recruiting 18 years or older.
- A Multicenter, Double Blind, Randomized, Placebo-Controlled Trial to Determine the Efficacy and Safety of Ganaxolone as Adjunctive Therapy for Adults With Drug-Resistant Partial-Onset Seizures Followed by Long-term Open-Label Treatment.
ganaxolone; Placebo

Seizure, Epilepsy, or Cerebral Malaria Clinical Trial using Oral Levetiracetam; Standard AED

University of Rochester - Recruiting 24 Months to 83 Months.
- .
Oral Levetiracetam; Standard AED

Tuberous Sclerosis Complex Clinical Trial

University of Alabama at Birmingham - Recruiting N/A to 6 Months.
- Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC.

Refractory Epilepsy Clinical Trial

Medtronic International Trading Sarl - Recruiting 18 years or older.
- Medtronic Registry for Epilepsy (MORE).

Seizures, or Epilepsy Clinical Trial using Patient Education

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Increasing Self-Efficacy and Outcome Expectations For Exercise in Adults With Epilepsy: An Educational Motivation Intervention - E-MOVE.
Patient Education

Partial Epilepsy Clinical Trial using YKP3089; Placebo

SK Life Science - Recruiting 18 years to 70 years.
- A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Response Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures, With Optional Open-Label Extension.
YKP3089; Placebo

Tuberous Sclerosis Complex-associated Refractory Seizures Clinical Trial using RAD001; Placebo

Novartis - Recruiting 1 year to 65 years.
- A Three-arm, Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Two Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) Who Have Refractory Partial-onset Seizures.
RAD001; Placebo

Epilepsy Clinical Trial using Electroencephalography; Electroencephalography and additional experimental tasks

Rennes University Hospital - Recruiting 18 years or older.
- Contribution of High Resolution EEG Functional Connectivity Measures to Presurgical Evaluation of Patients With Intractable Epilepsy.
Electroencephalography; Electroencephalography and additional experimental tasks

Traumatic Brain Injury Clinical Trial using valproate acid

Xijing Hospital - Recruiting 16 years to 65 years.
- Clinical Study on the Neuroprotection and Epilepsy Prevention of Valproate Acid Administered After Severe Traumatic Brain Injury.
valproate acid

Epilepsy Clinical Trial using Night Watch Seizure Detection Device and Warning System

Brain Sentinel - Recruiting 2 years or older.
- A Pivotal, Phase III Trial of Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients.
Night Watch Seizure Detection Device and Warning System

Epilepsy Clinical Trial using Vinpocetine

Emory University - Recruiting 18 years to 60 years.
- Cognitive Effects of Vinpocetine in Healthy Adults and Patients With Epilepsy.
Vinpocetine

Epilepsy Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 1 Month to 17 years.
- A Multicenter, Open-Label Study To Investigate The Safety, Tolerability, And Pharmacokinetics Of Lacosamide (LCM) Oral Solution (Syrup) As Adjunctive Therapy In Children With Partial-Onset Seizures.
Lacosamide

Seizure Disorder Clinical Trial using External Trigeminal Nerve Stimulation (eTNS)

NeuroSigma, Inc. - Recruiting 18 years to 65 years.
- External Trigeminal Nerve Stimulation for Epilepsy.
External Trigeminal Nerve Stimulation (eTNS)

Epilepsy Clinical Trial

New York University School of Medicine - Recruiting 18 years to 40 years.
- Women With Epilepsy: Pregnancy Outcomes and Deliveries.

Epilepsy Clinical Trial using Enhanced walking program

Children's Hospital of Eastern Ontario - Recruiting 8 years to 14 years.
- Enhancing Physical Activity in Children With Epilepsy: Impacts on Health and Quality of Life.
Enhanced walking program

Epilepsy Clinical Trial

Swedish Medical Center - Recruiting 10 years to 65 years.
- A Combined fMRI and Electrophysiological Study of Human Sensory Perception.

Epilepsy, or Seizures Clinical Trial

Capital District Health Authority, Canada - Recruiting 17 years or older.
- Neuroimaging Predictors of Treatment Failure in Adult New-onset Epilepsy.

Idiopathic Generalized Epilepsy Clinical Trial using Apomorphine (Experimental product)

Institut National de la Sant‚ Et de la Recherche M‚dicale, France - Recruiting 18 years to 40 years.
- Dopaminergic Reactivity In Idiopathic Generalized Epilepsy: A 'Proof Of Concept' Clinical, Pharmacological And Neurophysiological Study.
Apomorphine (Experimental product)

Epilepsy Clinical Trial

Columbia University - Recruiting 18 years to 65 years.
- Best Practices and Challenges in Medication Adherence for Individuals With Epilepsy.

Epilepsy, Seizures, Cognition Disorders, or Neuronal Migration Di Clinical Trial

Harvard University Faculty of Medicine - Recruiting N/A or older.
- Human Epilepsy Genetics--Neuronal Migration Disorders Study.

Epilepsy Clinical Trial

Beth Israel Deaconess Medical Center - Recruiting 18 years to 45 years.
- Comparison of Different Antiepileptic Drug Monotherapies for the Occurrence of Premenstrual Dysphoric Disorder Among Women With Epilepsy.

Epilepsy, or Glioma Clinical Trial

VU University Medical Center - Recruiting 18 years or older.
- Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy.

Epilepsy Clinical Trial using atkins diet; ability to follow low carbohydrate diet

University Health Network, Toronto - Recruiting 18 years or older.
- Efficacy, Tolerability and Long-Term Adherence of a Modified Ketogenic Diet (Atkins) in the Management of Pharmacoresistant Epilepsy.
atkins diet; ability to follow low carbohydrate diet