53 results found.

Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesop Clinical Trial using radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Trial Evaluating The Addition Of Trastuzumab To Trimodality Treatment Of Her2-Overexpressing Esophageal Adenocarcinoma.
radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

Metastatic Colorectal Cancer, Metastatic Gastric Cancer, Metastat Clinical Trial using CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract Cancers.
CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

Esophageal Cancer Clinical Trial using early oral feeding

Henan Cancer Hospital - Recruiting 18 years to 80 years.
- Early Oral Feeding Following Thoracolaparoscopic Oesophagectomy in Patients With Esophageal Cancer: a Randomized Clinical Trial.
early oral feeding

Esophageal Cancer Clinical Trial using wireless pulse oximeter (Wipox)

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- A Prospective Trial to Evaluate Whether Variations in Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy.
wireless pulse oximeter (Wipox)

Esophageal Cancer, or Gastric Cancer Clinical Trial using Afatinib (BIBW 2992)

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Afatinib (BIBW 2992) in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer.
Afatinib (BIBW 2992)

Esophageal Cancer, Bile Duct Neoplasms, Gastric Cancer, Liver Can Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Collection of Tissue, Blood and Other Specimens From Patients With Benign and Malignant Tumors of the Soft Tissue, Gastrointestinal Tract, and Other Intra-abdominal Sites..

Stomach Neoplasms; Esophageal Neoplasms; Metastatic Gastric Cance Clinical Trial using AUY922; BYL719

Novartis - Recruiting 18 years or older.
- A Phase IB, Multicenter, Open-label Dose Escalation Study of the PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric Cancer Carrying a Molecular Alteration of PIK3CA or an Amplification of HER2.
AUY922; BYL719

Cervical Cancer, Endometrial Cancer, Esophageal Cancer, Prostate Clinical Trial using Brachytherapy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- A Natural History Study of Patients Receiving High Dose Rate Brachytherapy.
Brachytherapy

Metastatic Cancers Other Than Melanoma That Express ESO Antigen, Clinical Trial using Anti-NY ESO-1 mTCR PBL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- Phase II Study of Metastatic Cancer That Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 Murine TCR-Gene Engineered Lymphocytes.
Anti-NY ESO-1 mTCR PBL; Aldesleukin; Cyclophosphamide; Fludarabine

Gastric Cancer Clinical Trial using trastuzumab [Herceptin]; capecitabine; cisplatin

Hoffmann-La Roche - Recruiting 18 years or older.
- .
trastuzumab [Herceptin]; capecitabine; cisplatin

Gastric Cancer Clinical Trial using trastuzumab [Herceptin]; Oxaliplatin; capecitabine; Radiation

Hoffmann-La Roche - Recruiting 18 years to 75 years.
- Safety and Tolerability of Oxaliplatin-Capecitabine-Trastuzumab Combination and Chemoradiotherapy in Adjuvant Setting in Operated HER2+ Patients With Gastric or Gastroesophageal Junction Adenocarcinoma: A Phase II Study (TOXAG Study).
trastuzumab [Herceptin]; Oxaliplatin; capecitabine; Radiation

Esophageal Cancer, Gastroesophageal Reflux Disease, Esophageal Di Clinical Trial using Survey of client health, personal habits, family history; Blood specimen for non-DNA and DNA parts; Biopsy of esophageal/stomach tissue, lymph nodes, tumor; Biopsies from routine clinical surveillance endoscopies

University of Pittsburgh - Recruiting 18 years or older.
- Esophageal Cancer Risk Registry.
Survey of client health, personal habits, family history; Blood specimen for non-DNA and DNA parts; Biopsy of esophageal/stomach tissue, lymph nodes, tumor; Biopsies from routine clinical surveillance endoscopies

Esophagectomy, or Esophageal Cancer Clinical Trial using Questionnaires

University of Pittsburgh - Recruiting 18 years or older.
- Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life.
Questionnaires

Gastric Cancer Clinical Trial using Rilotumumab; Placebo

Amgen - Recruiting 18 years or older.
- A Phase 3, Multicenter, Randomized, Double-Blind, Placebo Controlled Study of Rilotumumab (AMG102) With Epirubicin, Cisplatin, and Capecitabine (ECX) as First-line Therapy in Advanced MET-Positive Gastric or Gastroesophageal Junction Adenocarcinoma.
Rilotumumab; Placebo

Lung Cancer, Esophageal Cancer, Mesothelioma, Gastrointestinal Ne Clinical Trial using Mithramycin

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Phase II Evaluation of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum.
Mithramycin

Esophageal Cancer, Sleep Disturbance, or Quality of Life Clinical Trial using psychological counseling; prevention of sleep disorders in ICU

University of Padova - Recruiting 18 years or older.
- Quality of Life After Esophagectomy for Cancer - QOLEC1.
psychological counseling; prevention of sleep disorders in ICU

Esophageal Cancer, or Quality of Life Clinical Trial using nutritional counseling; respirology counseling

University of Padova - Recruiting 18 years or older.
- Quality of Life After Esophagectomy for Cancer - Step 2.
nutritional counseling; respirology counseling

Lung Cancer, Esophageal Cancer, Malignant Pleural Mesothelioma, S Clinical Trial using H1299 Lysate Vaccine; Cyclophosphamide; Celecoxib

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum.
H1299 Lysate Vaccine; Cyclophosphamide; Celecoxib

Locally Advanced (Unresectable) or Metastatic Adenocarcinoma of t Clinical Trial using Ipilimumab; Best Supportive care (BSC)

Bristol-Myers Squibb - Recruiting 18 years or older.
- A Randomized, Open-label, Two-arm Phase II Trial Comparing the Efficacy of Sequential Ipilimumab Versus Best Supportive Care Following First-line Chemotherapy in Subjects With Unresectable Locally Advanced/Metastatic Gastric or Gastro-esophageal Junction Cancer.
Ipilimumab; Best Supportive care (BSC)

Barrett's Esophagus, or Esophageal Neoplasms Clinical Trial using Radiofrequency Ablation(RFA) by HALO device.; Endoscopic mucosal resection(EMR) by mucosectomy kit.

Midwest Biomedical Research Foundation - Recruiting 18 years or older.
- Endoscopic Resection or Ablation for Patients With Dysplasia or Intramucosal Cancer in Barrett's Esophagus.
Radiofrequency Ablation(RFA) by HALO device.; Endoscopic mucosal resection(EMR) by mucosectomy kit.

Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesop Clinical Trial using oxaliplatin; leucovorin calcium; fluorouracil; therapeutic conventional surgery; radiation therapy; carboplatin; paclitaxel

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase II Trial of Modified FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Response Based Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced Adenocarcinoma of the Esophagus, Gastro-esophageal Junction, and Gastric Cardia.
oxaliplatin; leucovorin calcium; fluorouracil; therapeutic conventional surgery; radiation therapy; carboplatin; paclitaxel

Esophageal Cancer, or Gastric Cancer Clinical Trial using Regorafenib; 5-Fluorouracil; Leucovorin; Oxaliplatin

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Phase II Study of FOLFOX Plus Regorafenib in Patients With Unresectable or Metastatic Esophagogastric Cancer.
Regorafenib; 5-Fluorouracil; Leucovorin; Oxaliplatin

Esophageal Cancer Clinical Trial using Radiation Therapy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase I Study of Evaluating the Safety of Using a Simultaneous Integrated Boost for Dose Escalation in Patients With Esophageal Cancer.
Radiation Therapy

Mesolthelioma, Esophageal Cancer, or Lung Cancer Clinical Trial using Celecoxib; ISCOMATRIX (TM) Adjuvant; Autologous Tumor Cell Vaccine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Epigenetically-Modified Autologous Tumor Cell Vaccines With ISCOMATRIX(TM) Adjuvant and Oral Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thoracic Sarcomas, and Malignant Pleural Mesotheliomas.
Celecoxib; ISCOMATRIX (TM) Adjuvant; Autologous Tumor Cell Vaccine

Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cance Clinical Trial using FOLFOX regimen; docetaxel; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

Southwest Oncology Group - Recruiting 18 years or older.
- A Randomized Phase II Pilot Study Prospectively Evaluating Treatment for Patients Based on ERCC1(Excision Repair Cross-Complementing 1) for Advanced/Metastatic Esophageal, Gastric or Gastroesophageal Junction (GEJ) Cancer.
FOLFOX regimen; docetaxel; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

Esophageal Neoplasms, Adenocarcinoma of the Gastroesophageal Junc Clinical Trial using DKN-01; Paclitaxel

Dekkun Corporation - Recruiting 30 years or older.
- A Two Part, Phase 1, Multi-Center, Open-Label Study of DKN-01 in Combination With Weekly Paclitaxel in Patients With Relapsed or Refractory Esophageal Cancer or Gastro-Esophageal Junction Tumors.
DKN-01; Paclitaxel

Esophageal Cancer, or Esophageal Stenosis Clinical Trial using Partially covered SEMS; Fully covered SEMS

Foundation for Liver Research - Recruiting 18 years or older.
- A Randomized Comparison of a Fully Covered Self Expandable Metal Stent Versus a Partially Covered Self Expandable Metal Stent in Malignant Esophageal Strictures.
Partially covered SEMS; Fully covered SEMS

Esophageal Neoplasms Clinical Trial using Pronase; Control No pronase plus Dimethicone and sodium bicarbonate

Xijing Hospital of Digestive Diseases - Recruiting 18 years to 75 years.
- .
Pronase; Control No pronase plus Dimethicone and sodium bicarbonate

Esophageal Cancer, Esophageal Dysplasia, Stomach Cancer, or Stoma Clinical Trial using Hybrid knife; IT knife

Xijing Hospital of Digestive Diseases - Recruiting 18 years to 80 years.
- Comparison of O-type Hybrid Knife and IT Knife in Endoscopic Submucosal Dissection for Upper Gastrointestinal Neoplasms: a Prospective Randomized Controlled Trial.
Hybrid knife; IT knife

Localized Stage I-III Esophageal Cancer, or Gastroesophageal Junc Clinical Trial using nutritional and functional assessments

Memorial Sloan-Kettering Cancer Center - Recruiting 65 years or older.
- A Nutritional Management Algorithm in Older Patients With Locally Advanced Esophageal Cancer.
nutritional and functional assessments

Gastric Cancer Clinical Trial using albumin-bounded paclitaxel; S-1

Chinese Academy of Medical Sciences - Recruiting 18 years or older.
- Pase 2 Study of Albumin-bounded Paclitaxel Plus S-1 as First-line Chemotherapy for Locally Advanced or Metastatic Gastric or Gastro-esophageal Adenocarcinoma.
albumin-bounded paclitaxel; S-1

Stomach Cancer, Gastro-Esophageal(GE) Junction Cancer, Gastric (S Clinical Trial using Blood draw; Tissue tumor biopsy

Stanford University - Recruiting 18 years or older.
- Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma.
Blood draw; Tissue tumor biopsy

Hepatocellular Carcinoma, or Esophageal Cancer Clinical Trial

National Taiwan University Hospital - Recruiting 20 years to 90 years.
- Serum Biomarker Study for the Prognosis of Patients With Hepatocellular Carcinoma and Esophageal Cancer Undergoing Radiotherapy Using Multiplex Proximity Ligation Assay.

Esophageal Cancer, or Precancerous Condition Clinical Trial using erlotinib hydrochloride; laboratory biomarker analysis; biopsy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Chemoprevention Trial Using Erlotinib in Barrett's Esophagus With High-Grade Dysplasia.
erlotinib hydrochloride; laboratory biomarker analysis; biopsy

Esophageal Cancer Clinical Trial using cisplatin; fluorouracil; radiation therapy

National Cancer Institute (NCI) - Recruiting 20 years to 74 years.
- An Investigational Study of Chemoradiosensitivity Prediction With Genetic Profiling of Esophageal Biopsy for Squamous Cell Carcinoma of the Esophagus.
cisplatin; fluorouracil; radiation therapy

Breast Cancer, Colorectal Cancer, Esophageal Cancer, Head and Nec Clinical Trial using 18F-fluoromisonidazole; fluorescence angiography; laboratory biomarker analysis; infrared thermography; magnetic resonance imaging; therapeutic conventional surgery; [18F]-ML-10; fludeoxyglucose F 18; rubidium Rb-82

National Cancer Institute (NCI) - Recruiting N/A or older.
- Tumor Angiogenesis in Non-Small Cell Lung (NSCLC), Colorectal, Breast, Esophageal, Head and Neck Cancer: Radiology-Pathology and Prognostic Correlation.
18F-fluoromisonidazole; fluorescence angiography; laboratory biomarker analysis; infrared thermography; magnetic resonance imaging; therapeutic conventional surgery; [18F]-ML-10; fludeoxyglucose F 18; rubidium Rb-82

Esophageal Neoplasm, or Gastric Neoplasm Clinical Trial using Omegaven

University Hospitals, Leicester - Recruiting 18 years or older.
- Phase II Trial of Palliative Epirubicin, Oxaliplatin & Capecitabine (EOX) Chemotherapy Combined With Omega-3 Fish Oil Infusion (Omegaven) in Patients With Oesophagogastric Carcinoma.
Omegaven

Esophageal Cancer Clinical Trial using Neoadjuvant chemoradiotherapy; Adjuvant chemoradiotherapy

Zhejiang Cancer Hospital - Recruiting 18 years to 65 years.
- Prospective Randomized Phase ? Trial Comparing Preoperative Chemoradiotherapy (Paclitaxel and Carboplatin) Followed by Surgery to Surgery Followed by Postoperative Chemoradiotherapy (Paclitaxel and Carboplatin) for Esophageal Cancer.
Neoadjuvant chemoradiotherapy; Adjuvant chemoradiotherapy

Esophageal Squamous Cell Carcinoma Clinical Trial using S-1; Radiation therapy

Fudan University - Recruiting 18 years or older.
- Phase II Study of S-1 in Combination With Radiotherapy in Esophageal Squamous Cell Carcinoma.
S-1; Radiation therapy

Esophageal Cancer, or Gastric Cancer Clinical Trial using Oxaliplatin; Folinic Acid; 5-Fluorouracil; Ziv-aflibercept; Ziv-aflibercept Placebo

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- Randomized, Double-Blind, Placebo Controlled Phase II Study of FOLFOX +/- Ziv-Aflibercept in Patients With Advanced Esophageal and Gastric Cancer.
Oxaliplatin; Folinic Acid; 5-Fluorouracil; Ziv-aflibercept; Ziv-aflibercept Placebo

Esophageal Cancer Clinical Trial using HANAROSTENT TM covered Esophageal Stent

Weill Medical College of Cornell University - Recruiting 18 years or older.
- Prospective Evaluation of a New Covered Metal Stent for Malignant Lesions of the Esophagus.
HANAROSTENT TM covered Esophageal Stent

Esophageal Cancer Clinical Trial using S-1 and Paclitaxel; Paclitaxel and Cisplatin; 5-FU and Cisplatin

Peking University - Recruiting 18 years to 75 years.
- Combination Treatment of S-1 With Paclitaxel Versus Paclitaxel+Cisplatin and 5-Fu+Cisplatin as First-line Treatment in Advanced Esophageal Cancer.
S-1 and Paclitaxel; Paclitaxel and Cisplatin; 5-FU and Cisplatin

Esophageal Squamous Cell Carcinoma Resectable Clinical Trial using Nimotuzumab combined with paclitaxel and cisplatin

Zhejiang Cancer Hospital - Recruiting 18 years to 70 years.
- A Prospective, Single Arm, Multicenter, Phase II Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma.
Nimotuzumab combined with paclitaxel and cisplatin

Esophageal Cancer Clinical Trial using submucosal injection needle ; EUS; ordinary endosonography(EUS)

Sun Yat-sen University - Recruiting 18 years to 65 years.
- Efficacy Study of Endoscopic Ultrasound Combining With Submucosal Saline Injection for Pretreatment Staging of T1a and T1b in Patients With Early Esophageal Cancer.
submucosal injection needle ; EUS; ordinary endosonography(EUS)

Esophageal Cancer Clinical Trial using chemoradiotherapy; thalidomide; without thalidomide

Changzhou No.2 People's Hospital - Recruiting 20 years to 80 years.
- A Phase II Clinical Trial on VEGF Expression Interfered by Thalidomide Combined With Concurrent Chemoradiotherapy in Esophageal Cancer.
chemoradiotherapy; thalidomide; without thalidomide

Esophageal Carcinoma, or Esophageal Cancer Clinical Trial using Esophagectomy

UMC Utrecht - Recruiting 18 years to 75 years.
- Robot-assisted Minimally Invasive Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer. The ROBOT-trial: a Monocenter Randomized Controlled Trial..
Esophagectomy

Esophageal Cancer, or Gastro-esophageal Junction Cancer Clinical Trial using Home visits; standard

Odense University Hospital - Recruiting 18 years or older.
- Prospective, Randomized Trial of the Effects on HRQoL, Cost-Utility and Reintervention Rate, of Nurse Home Visits, in Patients With SEMS Treated Malignant Disease in the Esophagus and Cardia..
Home visits; standard

Esophageal Squamous Cell Carcinoma Clinical Trial using Nimotuzumab; Radiation therapy; radiation therapy; chemotherapy

Fudan University - Recruiting 18 years to 75 years.
- A Randomized Phase II Trial Evaluating The Addition Of Nimotuzumab To Chemoradiation For Patients With Esophageal Squamous Cell Carcinoma After Radical Esophagectomy Who Suffer With Lymph Nodes Recurrence.
Nimotuzumab; Radiation therapy; radiation therapy; chemotherapy

Esophageal Neoplasms Clinical Trial

Maastricht Radiation Oncology - Recruiting 18 years or older.
- Consequences of Positron-Emission-Tomography/Computed Tomography (PET/CT) Based Radiotherapy Treatment Planning for Clinical Outcome in Esophageal Cancer Patients.

Esophageal Cancer Clinical Trial using DCF

Wakayama Medical University - Recruiting 20 years or older.
- Phase I/II Trial of Combination Chemotherapy With Docetaxel, Cisplatin and 5-FU for Unresectable Advanced Esophageal Cancer..
DCF

Esophageal Cancer Clinical Trial using ERCC1 pathways analysis

University of Cologne - Recruiting 18 years or older.
- Prospective Study to Analyze the Predictive Role of Factors Implicated in the Signaling Pathway of ERCC1 in Response to Treatment With Neoadjuvant Radiochemotherapy in Patients With Esophageal Cancer.
ERCC1 pathways analysis

Esophageal Cancer Clinical Trial using Prosure; Ensure Plus

University of Dublin, Trinity College - Recruiting 18 years to 80 years.
- Randomized Double Blinded Trial to Investigate Effects of an Enteral Nutritional Supplement Enriched With Eicosapentaenoic Acid on Body Composition,Complications,Stress Response,Immune Function & Quality of Life in After Esophagectomy.
Prosure; Ensure Plus

Gastric Cancer, Esophageal Cancer, Pancreatic Cancer, or Colon Ca Clinical Trial using S-1

Hamamatsu University - Recruiting 20 years to 85 years.
- Pharmacokinetic and Pharmacodynamic Study of S-1 and Its Effects in Patients With the Digestive Organ Cancer With Reference to Genetic Polymorphism and Activity of CYP2A6 and DPD.
S-1