16 results found.

Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Ca Clinical Trial using fulvestrant; anastrozole

Alliance for Clinical Trials in Oncology - Recruiting 18 years or older.
- Alternate Approaches for Clinical Stage II or III Estrogen Receptor Positive Breast Cancer Neoadjuvant Treatment (ALTERNATE) in Postmenopausal Women: A Phase III Study.
fulvestrant; anastrozole

Ductal Breast Carcinoma in Situ, Estrogen Receptor-negative Breas Clinical Trial using therapeutic conventional surgery; radiation therapy; quality-of-life assessment

Roswell Park Cancer Institute - Recruiting 50 years or older.
- Phase II Trial of Single Fraction Radiation Therapy (SFRT) at Roswell Park Cancer Institute for Select Patients With Early Stage Breast Cancer.
therapeutic conventional surgery; radiation therapy; quality-of-life assessment

Advanced Metastatic Breast Cancer Clinical Trial using AZD2014; Fulvestrant

AstraZeneca - Recruiting 18 years or older.
- A Phase I, Open-label, Multicentre, Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AZD2014 Administered Orally in Combination With Intramuscular (IM) Fulvestrant to Patients With Estrogen Receptor Positive (ER+) Advanced, Metastatic Breast Cancer.
AZD2014; Fulvestrant

Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-posit Clinical Trial using zoledronic acid; laboratory biomarker analysis; therapeutic conventional surgery

City of Hope Medical Center - Recruiting N/A or older.
- A Pilot Study of the Impact of a Single Dose of Zoledronic Acid on Biomarkers in Breast Cancer.
zoledronic acid; laboratory biomarker analysis; therapeutic conventional surgery

Estrogen Receptor-positive Breast Cancer, Musculoskeletal Complic Clinical Trial using anastrozole; questionnaire administration; laboratory biomarker analysis; pharmacogenomic studies

Eastern Cooperative Oncology Group - Recruiting 18 years or older.
- A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS).
anastrozole; questionnaire administration; laboratory biomarker analysis; pharmacogenomic studies

Women With Estrogen Receptor Positive Breast Cancer Taking Aromat Clinical Trial using Arm A Directed exercise program; Observation

Christiana Care Health Services - Recruiting 40 years or older.
- Pilot Study for the Effect of Exercise Intervention in Breast Cancer Patients With Arthralgias Receiving Aromatase Inhibitors.
Arm A Directed exercise program; Observation

Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Ca Clinical Trial using docetaxel; carboplatin; trastuzumab; pertuzumab; goserelin acetate; therapeutic conventional surgery; whole breast irradiation; quality-of-life assessment; laboratory biomarker analysis; aromatase inhibition therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients With Hormone Receptor-Positive, HER2-Positive, Large Operable and Locally Advanced Breast Cancer Treated With Neoadjuvant Therapy of Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab (TCHP) With or Without Estrogen Deprivation.
docetaxel; carboplatin; trastuzumab; pertuzumab; goserelin acetate; therapeutic conventional surgery; whole breast irradiation; quality-of-life assessment; laboratory biomarker analysis; aromatase inhibition therapy

Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Ca Clinical Trial using systemic chemotherapy; tamoxifen citrate; anastrozole; exemestane; letrozole

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A PHASE III, RANDOMIZED CLINICAL TRIAL OF STANDARD ADJUVANT ENDOCRINE THERAPY +/-CHEMOTHERAPY IN PATIENTS WITH 1-3 POSITIVE NODES, HORMONE RECEPTOR-POSITIVE AND HER2-NEGATIVE BREAST CANCER WITH RECURRENCE SCORE (RS) OF 25 OR LESS. RXPONDER: A CLINICAL TRIAL RX FOR POSITIVE NODE, ENDOCRINE RESPONSIVE BREAST CANCER.
systemic chemotherapy; tamoxifen citrate; anastrozole; exemestane; letrozole

Estrogen Receptor-positive Breast Cancer, Stage I Breast Cancer, Clinical Trial using tamoxifen citrate; polymerase chain reaction; pharmacological study; gene expression analysis; immunohistochemistry staining method; pharmacogenomic studies; matrix-assisted laser desorption/ionization time of flight mass spectrometry; polymorphism analysis; therapeutic conventional surgery; nucleic acid sequencing; protein analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Pilot Study to Analyze a Novel Mechanism Underlying Response to Tamoxifen Therapy in Breast Cancer Patients.
tamoxifen citrate; polymerase chain reaction; pharmacological study; gene expression analysis; immunohistochemistry staining method; pharmacogenomic studies; matrix-assisted laser desorption/ionization time of flight mass spectrometry; polymorphism analysis; therapeutic conventional surgery; nucleic acid sequencing; protein analysis

Breast Cancer, or Endometrial Cancer Clinical Trial using HLA vaginal gel (HyaloGYNr),; questionnaires

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Single-Arm Clinical Trial Investigating the Feasibility of a Non-Hormonal Vaginal Moisturizer in Hormone-Receptor Positive Postmenopausal Cancer Survivors Experiencing Estrogen Deprivation Symptoms.
HLA vaginal gel (HyaloGYNr),; questionnaires

Breast Cancer Clinical Trial using Enzalutamide; exemestane; Placebo (for enzalutamide)

Medivation, Inc. - Recruiting 18 years or older.
- A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Efficacy and Safety of Enzalutamide in Combination With Exemestane in Patients With Advanced Breast Cancer That Is Estrogen or Progesterone Receptor-Positive and HER2-Normal.
Enzalutamide; exemestane; Placebo (for enzalutamide)

Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-posit Clinical Trial using veliparib; paclitaxel; carboplatin; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of ABT-888 (Veliparib) in Combination With Weekly Carboplatin and Paclitaxel in Advanced Solid Tumors.
veliparib; paclitaxel; carboplatin; pharmacological study; laboratory biomarker analysis

Estrogen Receptor-positive Breast Cancer, Progesterone Receptor-p Clinical Trial using therapeutic estradiol; exemestane; laboratory biomarker analysis; enzyme-linked immunosorbent assay

University of Arizona - Recruiting N/A or older.
- A Pilot Study Of Estradiol Followed By Exemestane For Post-Menopausal Hormone Receptor Positive Metastatic Breast Cancer After Prior Failed Endocrine Therapy: Reversing Endocrine Resistance.
therapeutic estradiol; exemestane; laboratory biomarker analysis; enzyme-linked immunosorbent assay

Breast Cancer Clinical Trial using letrozole; laboratory biomarker analysis; questionnaire administration; breast imaging study; dynamic contrast-enhanced magnetic resonance imaging; neoadjuvant therapy; quality-of-life assessment; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Study of Neoadjuvant Letrozole for Postmenopausal Women With Estrogen Receptor Positive Ductal Carcinoma In SITU (DCIS).
letrozole; laboratory biomarker analysis; questionnaire administration; breast imaging study; dynamic contrast-enhanced magnetic resonance imaging; neoadjuvant therapy; quality-of-life assessment; therapeutic conventional surgery

Breast Cancer Clinical Trial

Korean Breast Cancer Study Group - Recruiting N/A or older.
- Assessment of Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women With Hormone Receptor Positive Breast Cancer.

Breast Cancer Clinical Trial using Zoladex+AI; TAM

Fudan University - Recruiting 18 years or older.
- A Randomized ,Open Label Study Comparing the Efficacy of Zoladexr Combined With Arimidexr for 3-2 Years After Selective Estrogen Receptor Modulators (SERMs) as an Adjuvant Therapy for 2-3 Years Versus Continuing Tamoxifen up to 5 Years for Premenopausal Early Breast Cancer Patients With Hormone Receptor Positive, Lymph Node Positive or Tumorò 4cm..
Zoladex+AI; TAM