48 results found.

Secondary Hyperparathyroidism; Chronic Kidney Disease Clinical Trial using AMG 416; cinacalcet

Amgen - Recruiting 18 years to 85 years.
- A Multicenter, Multiple-dose, Two-arm, Active-controlled, Double-blind, Double-dummy Study to Compare the Therapeutic Efficacy and Safety of Oral Doses of Cinacalcet HCl With Intravenous Doses of AMG 416 in Hemodialysis Subjects With Secondary Hyperparathyroidism.
AMG 416; cinacalcet

Hyperparathyroidism, Secondary Clinical Trial using AMG 416

Amgen - Recruiting 18 years or older.
- A Multicenter Single-arm Extension Study to Describe the Long-term Efficacy and Safety of AMG 416 in the Treatment of Secondary Hyperparathyroidism in Subjects With Chronic Kidney Disease on Hemodialysis.
AMG 416

Chronic Renal Failure Requiring Hemodialysis Clinical Trial using Epoetin Hospira

Hospira, Inc. - Recruiting 18 years to 80 years.
- A Phase 3 Long-Term Safety Study of Subcutaneous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment.
Epoetin Hospira

Chronic Kidney Insufficiency, Hemodialysis Treatment, or Diuresis Clinical Trial using Hydrochlorothiazide and furosemide

Corporacion Parc Tauli - Recruiting 18 years to 90 years.
- Randomized Open Clinical Trial to Compare the Effectiveness of the Administration of Diuretics in Hemodialysis Patients With Residual Renal Function in Single Centre.
Hydrochlorothiazide and furosemide

Anemia, or Kidney Failure, Chronic Clinical Trial using Sotatercept

Celgene Corporation - Recruiting 18 years or older.
- A Phase 2 Multicenter, Randomized, Open-Label , Multiple-Dose Study of Intravenous and Subcutaneous Administration of Sotatercept (ACE-011) in Subjects With End-Stage Kidney Disease on Hemodialysis Switched From Erythropoiesis Stimulating Agents With Staggered Dose Group Escalation in Part 1 Followed by a Parallel Group, Active Controlled Study of Selected Dose(s) and Regimen(s) in Part 2: To Evaluate the Pharmacokinetics, Safety, Tolerability, Efficacy, Dosing Regimen, and Pharmacodynamics of Sotatercept.
Sotatercept

End Stage Renal Disease Clinical Trial using Dialysis session of at least 4.25 hours

University of Pennsylvania - Recruiting 18 years or older.
- Time to Reduce Mortality in End-Stage Renal Disease (TiME) Trial.
Dialysis session of at least 4.25 hours

Arteriovenous Fistula Clinical Trial using SRM003; Participating Site's standard practice

Shire Development LLC - Recruiting 18 years or older.
- A Phase 2, Single-blind, Randomized, Controlled, Multi-center Study to Evaluate the Efficacy and Safety of SRM003 (Vascugelr) in Improving the Rate of Arteriovenous Fistula Maturation and Use in Subjects Undergoing Surgery for Creation of an Arteriovenous Fistula for Hemodialysis Access.
SRM003; Participating Site's standard practice

Arteriovenous Graft Clinical Trial using SRM003; Participating Site's standard practice

Shire Development LLC - Recruiting 18 years or older.
- A Phase 2, Single-blind, Randomized, Controlled, Multi-center Study to Evaluate the Efficacy and Safety of SRM003 (Vascugelr) in the Treatment of Subjects With Vascular Injury Resulting From Arteriovenous Graft Surgery for Hemodialysis Access.
SRM003; Participating Site's standard practice

End Stage Renal Disease, Kidney Disease, or Protein Energy Wastin Clinical Trial using PINTA 745; Placebo

Pinta Biotherapeutics - Recruiting 18 years to 85 years.
- A Randomized, Double-blind, Pilot Study of PINTA 745, an Anti-myostatin Peptibody, in Patients With End Stage Renal Disease Who Require Maintenance Hemodialysis and Have Protein Energy Wasting.
PINTA 745; Placebo

Chronic Kidney Disease Clinical Trial using No intervention

Janssen Inc. - Recruiting 18 years or older.
- A Prospective, Observational, Randomized Comparative Study of Case Managed Versus Non-case Managed Initiation of Hemodialysis.
No intervention

Kidney Failure, Chronic Clinical Trial using ticagrelor

AstraZeneca - Recruiting 18 years to 80 years.
- A Single Dose, Randomized, Open-Label, Parallel Group Study Comparing the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Ticagrelor in Hemodialyisis Patients to Subjects With Normal Renal Function.
ticagrelor

Renal Failure Chronic Requiring Hemodialysis Clinical Trial using intensive sodium management

Renal Research Institute - Recruiting 18 years or older.
- A Multi-center, Randomized, Controlled and Prospective Pilot Study on the Effects of Intensified Sodium Management on Hospitalization in Chronic Hemodialysis Patients..
intensive sodium management

Renal Failure Clinical Trial using 2008 Sorbent System

Renal Research Institute - Recruiting 18 years to 88 years.
- Hemodialysis With the 2008 Sorbent System: A Pilot Evaluation of Different Treatment Prescriptions.
2008 Sorbent System

Anaemia Clinical Trial using GSK1278863; Placebo; rhEPO

GlaxoSmithKline - Recruiting 18 years or older.
- A Phase IIB, Randomized, Blinded, Dose-ranging, Active-controlled, Parallel-group, Multi-center Study to Evaluate the Dose Response Relationship of GSK1278863 Over the First 4 Weeks of Treatment and Evaluate the Safety and Efficacy of GSK1278863 Over 24 Weeks in Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Switch From Recombinant Human Erythropoietin.
GSK1278863; Placebo; rhEPO

Anaemia Clinical Trial using GSK1278863; Placebo

GlaxoSmithKline - Recruiting 20 years or older.
- A 4-Week, Phase II, Randomized, Double-Blind, Dose-Ranging, Placebo-Controlled, Parallel-Group, Multi-Center Study to Evaluate the Safety, Efficacy and Pharmacokinetics of GSK1278863 in Japanese Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease.
GSK1278863; Placebo

Renal Failure Clinical Trial using pharmacokinetic monitoring

Midwestern University - Recruiting N/A or older.
- Pharmacokinetic Assessment of Ceftazidime in Intermittent Hemodialysis Patients.
pharmacokinetic monitoring

Chronic Renal Failure Clinical Trial using Fragmin

Pfizer - Recruiting 18 years to 75 years.
- A Phase IIIb Open Label Study To Optimize The Single Bolus Dose Of Dalteparin Sodium For The Prevention Of Clotting Within The Extracorporeal System During Hemodialysis Procedures For Patients With Chronic Renal Insufficiency: The Parrot Study.
Fragmin

Hemodialysis, or Hyperphosphatemia Clinical Trial using Lanthanum Carbonate; Calcium Carbonate

Translational Research Informatics Center, Kobe, Hyogo, Japan - Recruiting N/A or older.
- Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate on Cardiovascular Mortality and Morbidity in Patients With Chronic Kidney Disease on Hemodialysis (CKD5D).
Lanthanum Carbonate; Calcium Carbonate

Dialysis Access Malfunction Clinical Trial using Angiography with IVUS

Baylor Research Institute - Recruiting 18 years or older.
- A Prospective Randomized Feasibility Trial Comparing Angiography and Angiography With IVUS for Treatment of Hemodialysis Access Failures.
Angiography with IVUS

Anemia Clinical Trial using methoxy polyethylene glycol-epoetin beta [Mircera]

Hoffmann-La Roche - Recruiting 5 years to 17 years.
- An Open Label Multi-center, Multiple Dose Study to Determine the Optimum Starting Dose of Intravenous MIRCERA for Maintenance Treatment of Anemia in Pediatric Patients With Chronic Kidney Disease on Dialysis..
methoxy polyethylene glycol-epoetin beta [Mircera]

Chronic Renal Failure Clinical Trial using Rivaroxaban 10 mg

AZ Sint-Jan AV - Recruiting 18 years or older.
- Finding the Optimal Dose of Rivaroxaban in Hemodialysis Patients.
Rivaroxaban 10 mg

Anemia, or Renal Insufficiency, Chronic Clinical Trial using BAY85-3934; Epoetin alfa/beta

Bayer - Recruiting 18 years or older.
- A Randomized, Parallel Group, Open-label, Multicenter Study to Investigate the Efficacy and Safety of Oral BAY85-3934 and Active Comparator (Epoetin Alfa / Beta) in the Maintenance Treatment of Subjects With Anemia Associated With Chronic Kidney Disease Who Are on Dialysis and on Treatment With an Erythropoiesis-stimulating Agent in the United States and Japan.
BAY85-3934; Epoetin alfa/beta

Anemia Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Non-interventional Study on the Use of Mircera in the Treatment of Chronic Renal Anemia in Patients With Chronic Kidney Disease Stages III-IV Not on Dialysis and in Patients on Stage V on Hemodialysis.

Chronic Kidney Disease Clinical Trial using The FLEX System will be used to percutaneously create a fistula in CKD patients who require hemodialysis vascular access

TVA Medical Inc. - Recruiting 18 years or older.
- Novel Endovascular Access Trial (NEAT): A Study of the FLEX System for Percutaneous AV Fistula Creation in Hemodialysis Patients.
The FLEX System will be used to percutaneously create a fistula in CKD patients who require hemodialysis vascular access

End-stage Renal Disease, or Kidney Failure, Chronic Clinical Trial using HAVG graft implantation

Humacyte, Inc. - Recruiting 18 years to 75 years.
- A Pilot Study for Evaluation of the Safety and Efficacy of Humacyte's Human Acellular Vascular Graft for Use as a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease.
HAVG graft implantation

Uremic Pruritus Clinical Trial using Nalfurafine hydrochloride 2.5æg; Nalfurafine hydrochloride 5æg; Nalfurafine hydrochloride 10æg; Placebo

Mitsubishi Tanabe Pharma Corporation - Recruiting 18 years or older.
- A Phase 2, Randomized, Double-blind, Placebo-controlled, Fixed-dose, Parallel-group, Multicenter, Efficacy, and Safety Study of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis.
Nalfurafine hydrochloride 2.5æg; Nalfurafine hydrochloride 5æg; Nalfurafine hydrochloride 10æg; Placebo

Hyperphosphatemia Clinical Trial using Lanthanum Carbonate (Fosrenol, BAY77-1931) - chewable tablet

Bayer - Recruiting N/A or older.
- Special Drug Use Investigation of Fosrenol (Long-term Investigation for Patients With Hemodialysis).
Lanthanum Carbonate (Fosrenol, BAY77-1931) - chewable tablet

Vitamin K1 to Slow the Progression of Thoracic Aortic and Coronar Clinical Trial using Vitamin K1

RWTH Aachen University - Recruiting 18 years or older.
- Vitamin K1 to Slow Progression of Vascular Calcification in Hemodialysis Patients.
Vitamin K1

Chronic Renal Failure Requiring Hemodialysis Clinical Trial using Epoetin Hospira

Hospira, Inc. - Recruiting 18 years to 80 years.
- A Phase 3 Long-Term Safety Study of Intravenous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment.
Epoetin Hospira

End Stage Renal Disease Clinical Trial using Treatment modification

The Rogosin Institute - Recruiting N/A or older.
- Treatment Modification and Symptom Burden in High-Risk Dialysis Patients.
Treatment modification

Stage 5 Chronic Kidney Disease Clinical Trial using Multidisciplinary, intensive and collaborative care

National University, Singapore - Recruiting 21 years or older.
- Impact of a Multidisciplinary Intensive Management Clinic on Clinical, Patient-Reported and Economic Outcomes in Multi-Ethnic Asian Incident Hemodialysis Patients.
Multidisciplinary, intensive and collaborative care

Severe Sepsis, or Septic Shock Clinical Trial using continuous veno-venous hemodialysis

Johannes Gutenberg University Mainz - Recruiting 18 years or older.
- Cerebrovascular Autoregulation in Patients With Severe Sepsis and Septic Shock, Influence of Renal Replacement Therapy.
continuous veno-venous hemodialysis

Septic Shock, or Acute Renal Failure (as Defined by the 'Failure' Clinical Trial using hemodialysis

Centre Hospitalier Universitaire Dijon - Recruiting 18 years or older.
- Early Initiation of Dialysis at the Failure Stage Versus Deferred Dialysis in Intensive Care Unit Patients in Premature Phase of the Septic Shock Who Develop Acute Renal Insufficiency. Randomized, Controlled Superiority Trial. IDEAL-ICU (Initiation od Dialysis Early vs Late in Intensive Care Unit) Study Group..
hemodialysis

Hemodialysis Patients Clinical Trial using Three months of regular perdialytic physical activity (cycling)

Hospices Civils de Lyon - Recruiting 18 years or older.
- Effects of Regular Perdialytic Physical Activity on the Peripheral Microcirculation in Chronic Hemodialysis Patients.
Three months of regular perdialytic physical activity (cycling)

Kidney Failure, Chronic, or End Stage Renal Disease, Requiring Di Clinical Trial using NxStage System One

NxStage Medical - Recruiting 18 years or older.
- Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStager System OneT.
NxStage System One

End-stage Renal Disease Clinical Trial

Kyungpook National University - Recruiting 18 years or older.
- A Prospective, Multicenter, Observational Study to Evaluate the Impact of Peritoneal Dialysis Compared With Hemodialysis on Iron Metabolism and Hepcidin.

Chronic Hepatitis C, Chronic Hepatitis B, Biopsy, or Hemodialysis Clinical Trial using Percutaneous liver biopsy

National Taiwan University Hospital - Recruiting N/A or older.
- Safety Profiles of Percutaneous Liver Biopsy in Hemodialysis Patients With Chronic Hepatitis C Pre-treated With 1-Deamino-8- D-Arginine Vasopressin.
Percutaneous liver biopsy

Kidney Failure, Chronic Clinical Trial using Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.

Consorzio Mario Negri Sud - Recruiting 18 years or older.
- Effects of the Dose of Erythropoiesis Stimulating Agents on Cardiac-cerebrovascular Outcomes Quality of Life and Costs in Hemodialysis Patients. The Clinical Evaluation of the DOSe of Erythropoietins (C.E. DOSE) Trial.
Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.

Chronic Kidney Disease, or Hemodialysis Clinical Trial

Renal Research Institute - Recruiting 18 years to 88 years.
- Red Blood Cell Lifespan and Inflammation in Dialysis Patients.

Hemodialysis, End-stage Renal Disease, Hypertension, or Intradial Clinical Trial

University of Texas Southwestern Medical Center - Recruiting 18 years to 85 years.
- Mechanisms and Treatment of Intradialytic Hypertension - Sodium.

Renal Failure Clinical Trial using a pre-heparin-coated hemodialysis filter; Hepran

Oslo University Hospital - Recruiting 18 years to 90 years.
- The Effect of a Heparin-coated Dialysis Filter (Evodial) on Clotting and Intravascular Coagulation During Hemodialysis (HD) When Compared to a Conventional Polyflux Filter (170H).
a pre-heparin-coated hemodialysis filter; Hepran

Hemodialysis Clinical Trial using Sub-total Parathyroidectomy

Guangdong General Hospital - Recruiting 18 years to 80 years.
- Sub-total Parathyroidectomy Reduces Vascular Calcification in Haemodialysis Patients.
Sub-total Parathyroidectomy

Hypertension, or Hemodialysis Clinical Trial using BP education and BP self-regulation; Supportive Educative Nursing Intervention

Wayne State University - Recruiting 18 years or older.
- Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nursing Intervention.
BP education and BP self-regulation; Supportive Educative Nursing Intervention

End-Stage Renal Disease Clinical Trial using Cool Dialysate

National Institute of Nursing Research (NINR) - Recruiting 21 years to 75 years.
- The Effects of Hemodialysis on the Sleep/Wake Cycle.
Cool Dialysate