49 results found.

Insulin Resistance Clinical Trial using Metreleptin

National Institutes of Health Clinical Center (CC) - Recruiting 5 years or older.
- Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance.
Metreleptin

Branched-chain Amino Acid Metabolism, or Insulin Sensitivity Clinical Trial using Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training; GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery

Duke University - Recruiting 30 years to 65 years.
- Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes: Responses to Exercise Training and Gastric Bypass Surgery.
Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training; GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery

Essential Hypertension Complicated by Type 2 Diabetes Mellitus Clinical Trial using Azilsartan; Telmisartan

Takeda - Recruiting 20 years or older.
- A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-R.
Azilsartan; Telmisartan

Metabolic Syndrome, or Insulin Resistance Clinical Trial using TA-65; Placebo

University of Connecticut - Recruiting 35 years to 70 years.
- The Effects of the Telomerase Activator TA-65 on Insulin Resistance, Inflammation, and Metabolic Syndrome.
TA-65; Placebo

Abdominal Obesity, Insulin Resistance, or Hypertriglyceridemia Clinical Trial using Acipimox; Placebo

Massachusetts General Hospital - Recruiting 18 years to 55 years.
- The Effects of Short Term Acipimox Treatment on Skeletal Muscle Phosphocreatine Recovery in Obesity.
Acipimox; Placebo

Prediabetes, Insulin Resistance, or Vascular Diseases Clinical Trial using Time-Restricted Feeding; Grazing

Pennington Biomedical Research Center - Recruiting 30 years to 65 years.
- Time-Restricted Feeding to Improve Glucose Tolerance and Vascular Condition in Obese Humans.
Time-Restricted Feeding; Grazing

Diabetes Mellitus, or Insulin Resistance Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Studies of Molecular Genetics of Insulin Secretion, Insulin Action, and Diabetes Mellitus.

Morbid Obesity, Diabetes Mellitus Type 2, Insulin Resistance, Obs Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Study of the Phenotype of Overweight and Obese Adults.

Glucose Metabolism, or Insulin Resistance Clinical Trial using CP-945,598; Hypoglycemic Clamp; Euglycemic-Hyperinsulinemic Clamp

National Institutes of Health Clinical Center (CC) - Recruiting 21 years to 55 years.
- The Roles of Endocannabinoids in Insulin Secretion and Action.
CP-945,598; Hypoglycemic Clamp; Euglycemic-Hyperinsulinemic Clamp

Depression, or Impaired Glucose Tolerance Clinical Trial using The Blues Program; Hey Durham

National Institutes of Health Clinical Center (CC) - Recruiting 12 years to 17 years.
- Mood and Insulin Resistance in Adolescents At-Risk for Diabetes.
The Blues Program; Hey Durham

Metabolic Syndrome X, Diastolic Dysfunction, or Insulin Resistanc Clinical Trial using Lifestyle Counseling; Metformin

Universidade do Porto - Recruiting 40 years to 64 years.
- Metformin in the Diastolic Dysfunction of Metabolic Syndrome: MET-DIME Trial.
Lifestyle Counseling; Metformin

Gastric Cancer With Metabolic Syndrome or Metabolic Disease Clinical Trial using subtotal gastrectomy with gastroduodenostomy; subtotal gastrectomy with Roux-en-Y gastrojejunostomy,; total gastrectomy with Rou-en-Y esophagojejunostomy

Yonsei University - Recruiting 20 years to 80 years.
- .
subtotal gastrectomy with gastroduodenostomy; subtotal gastrectomy with Roux-en-Y gastrojejunostomy,; total gastrectomy with Rou-en-Y esophagojejunostomy

Obesity Clinical Trial using metformin; Conjugated Linoleic Acid; Placebo; Healthy habits program

Laboratorios Silanes S.A. de C.V. - Recruiting 8 years to 18 years.
- Effect of an Intervention Program With Healthy Habits Plus Metformin or Conjugated Linoleic Acid Over Clinical Parameters and Molecular Pathways of Insulin Resistance in Obese Pediatric Patients.
metformin; Conjugated Linoleic Acid; Placebo; Healthy habits program

Obesity, Insulin Resistance, Overweight, or Diabetes Mellitus, Ty Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 8 years to 25 years.
- Natural History of Type 2 Diabetes Mellitus in Children and Young Adults.

Insulin Resistance, Type 2 Diabetes Mellitus, Obesity, Androgen D Clinical Trial using Acyline; Testosterone 1.62% gel; Letrozole; Placebo gel (for Testosterone 1.62% gel); Placebo pill (for Letrozole)

University of Washington - Recruiting 25 years to 55 years.
- Androgen-mediated Pathways in the Regulation of Insulin Sensitivity in Men.
Acyline; Testosterone 1.62% gel; Letrozole; Placebo gel (for Testosterone 1.62% gel); Placebo pill (for Letrozole)

Metabolic Syndrome X Clinical Trial using Ezetimibe; Placebo

Laval University - Recruiting 18 years to 60 years.
- Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study.
Ezetimibe; Placebo

Insulin Resistance, or Hypertension Clinical Trial using Renal denervation using Medtronic Symplicity System (mono-electrode)

Ume† University - Recruiting 18 years or older.
- Metabolic and Cardiovascular Effects of Renal Denervation.
Renal denervation using Medtronic Symplicity System (mono-electrode)

Acromegaly Clinical Trial

Massachusetts General Hospital - Recruiting 18 years to 75 years.
- Ectopic Lipid Deposition and Insulin Resistance in After Treatment of Acromegaly.

Insulin Resistance Clinical Trial using Omega-3; placebo

Mayo Clinic - Recruiting 18 years to 65 years.
- Dietary Omega-3 Fatty Acids as a Therapeutic Strategy in Insulin Resistant Humans.
Omega-3; placebo

Type 1 Diabetes Clinical Trial using Metformin; Placebo

T1D Exchange Clinic Network Coordinating Center - Recruiting 12 years to 19 years.
- Metformin Therapy for Overweight Adolescents With Type 1 Diabetes (T1D)--Insulin Clamp Ancillary Study for Assessment of Insulin Resistance.
Metformin; Placebo

Inflammation, Macrophage Infiltration, or Cardiovascular Disease Clinical Trial using Sitagliptin; Placebo

Washington University School of Medicine - Recruiting 18 years to 65 years.
- A Double Blind, Randomized, Placebo Controlled Study to Determine the Physiological Effectiveness of Januvia (100 mg/d) for Reducing Inflammation and Increasing Endothelial Progenitor Cell Number in Human Immunodeficiency Virus (HIV) Infected Men and Women With Insulin Resistance and Central Adiposity..
Sitagliptin; Placebo

Diabetes, Metabolic Syndrome, or Insulin Resistance Clinical Trial using pegvisomant

University of California, San Francisco - Recruiting 18 years to 80 years.
- Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Insulin Resistance But Without Diabetes.
pegvisomant

Obesity, or Insulin Resistance Clinical Trial using Omega3 and an hypocaloric diet.; Sunflower oil with an hypocaloric diet.

Coordinaci¢n de Investigaci¢n en Salud, Mexico - Recruiting 12 years to 18 years.
- The Impact of Using omega3 Long-chain Polyunsaturated Fatty Acids in Weight Loss and Insulin Resistance in Obese Adolescents.
Omega3 and an hypocaloric diet.; Sunflower oil with an hypocaloric diet.

Polycystic Ovary Syndrome, or Insulin Resistance Clinical Trial using acupuncture

The First Affiliated Hospital of Guangzhou Medical University - Recruiting 18 years to 49 years.
- The Effect of Acupuncture on Insulin Sensitivity in Insulin Resistance Women With Polycystic Ovary Syndrome A Pilot Study.
acupuncture

Obesity, Insulin Resistance, or Diabetes Clinical Trial using Every Little Step Counts Intervention

Arizona State University - Recruiting 14 years to 16 years.
- Community-Based Diabetes Prevention Program for Obese Latino Youth: Every Little Step Counts.
Every Little Step Counts Intervention

CHB Patients Without Significant Alcohol Consumption or Other Kno Clinical Trial

Seoul National University Boramae Hospital - Recruiting 20 years to 80 years.
- Association Between Insulin Resistance and Hepatic Fibrosis in Combined Chronic Hepatitis B and Non-alcoholic Fatty Liver Disease.

Obesity, Hyperglycemia, or Insulin Resistance Clinical Trial using Bifidobacterium animalis ssp. lactis 420; Polydextrose

Danisco - Recruiting 18 years to 65 years.
- The Effect of Separate or Combined Supplementation of Probiotic (Bifidobacterium Lactis B420) and Polydextrose on Body Fat Mass.
Bifidobacterium animalis ssp. lactis 420; Polydextrose

Insulin Resistance Clinical Trial

University of California, San Francisco - Recruiting 18 years to 60 years.
- Impact of Hepatitis C on Insulin Sensitivity and Insulin Secretion in Latinos.

Abdominal Obesity Metabolic Syndrome, Insulin Resistance, or Hype Clinical Trial using Eplerenone; Placebo

Maastricht University Medical Center - Recruiting 40 years to 65 years.
- Effects of Aldosterone Antagonism on Insulin-mediated Microvascular Function in Subjects With the Metabolic Syndrome.
Eplerenone; Placebo

Spinal Cord Injury, or Insulin Resistance Clinical Trial using Insulin iontophoresis; Placebo Iontophoresis; Acetylcholine Iontophoresis; Heat application

James J. Peters Veterans Affairs Medical Center - Recruiting 20 years to 69 years.
- Insulin Resistance and Microvascular Blood Flow in Spinal Cord Injury.
Insulin iontophoresis; Placebo Iontophoresis; Acetylcholine Iontophoresis; Heat application

Obesity, Insulin Resistance, Triglycerides, or Diabetes Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 30 years to 65 years.
- Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and Contractors.

Insulin Sensitivity/Resistance, Obesity, or Weight Loss Clinical Trial using PART 2: 12 week calorie restriction weight loss program

Garvan Institute of Medical Research - Recruiting 26 years to 75 years.
- Insulin-sensitive Obesity: Prospective and Interventional Studies.
PART 2: 12 week calorie restriction weight loss program

Sub-optimal Vitamin D Status, Pre-diabetes, or Insulin Resistance Clinical Trial using Vitamin D3 supplementation

Queen's University, Belfast - Recruiting 18 years or older.
- Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in People at High Risk of Type 2 Diabetes and Cardiovascular Disease (The DIR Study).
Vitamin D3 supplementation

Insulin Resistance, or Chronic Heart Failure Clinical Trial using Metformini hydrochloridum (Siofor 1000 tbl, Berlin); placebo

Institute for Clinical and Experimental Medicine - Recruiting 40 years to 70 years.
- Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes.
Metformini hydrochloridum (Siofor 1000 tbl, Berlin); placebo

Diabetes Mellitus Type 2 in Obese, or Obesity Clinical Trial

Mayo Clinic - Recruiting 21 years to 55 years.
- Epigenetics and the Origin of Muscle Insulin Resistance in Humans.

Type 2 Diabetes Clinical Trial using Mirtoselect

University of Aberdeen - Recruiting 40 years to 70 years.
- Study of Acute Oral Administration of Anthocyanins on Insulin Resistance.
Mirtoselect

Hypoglycaemia Clinical Trial using GLP-1; Placebo (Saline); TNF-alfa; OGTT; IVGTT

Rigshospitalet, Denmark - Recruiting 18 years to 40 years.
- Mechanisms of Insulin Resistance in Critical Illness: Role of Systemic Inflammation and GLP-1.
GLP-1; Placebo (Saline); TNF-alfa; OGTT; IVGTT

Obesity, or Insulin Resistance Clinical Trial using Insulin; NG-monomethyl-L-arginine

Mayo Clinic - Recruiting 18 years to 50 years.
- Regulation of the Plasma Triglyceride Extraction in Muscle in Insulin Resistance.
Insulin; NG-monomethyl-L-arginine

Obesity, or Insulin Resistance Clinical Trial using Low-Carbohydrate Diet; Low-Fat Diet

Stanford University - Recruiting 18 years to 50 years.
- Do Genotype Patterns Predict Weight Loss Success for Low Carb vs. Low Fat Diets?.
Low-Carbohydrate Diet; Low-Fat Diet

Insulin Resistance Clinical Trial using Estradiol

University of Colorado, Denver - Recruiting 45 years to 70 years.
- TIME PAST MENOPAUSE, DURATION OF ESTROGEN DEFICIENCY, AND INSULIN ACTION.
Estradiol

Hyperprolactinemia, or Insulin Resistance Clinical Trial using Cabergoline

University of Aarhus - Recruiting 18 years to 70 years.
- Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment.
Cabergoline

Metabolic Syndrome, Non Alcoholic Fatty Liver Disease, or Insulin Clinical Trial using glucomannan; lifestyle intervention

Bambino Ges— Hospital and Research Institute - Recruiting 4 years to 16 years.
- Study of the Efficacy and Tolerability of Glucomannan on Children Affected by NAFLD.
glucomannan; lifestyle intervention

Metabolic Syndrome, Insulin Resistance, or Dyslipidemia Clinical Trial using Glucose; Fructose; High-Fructose Corn Syrup; No sugar (Aspartame)

University of California, Davis - Recruiting 18 years to 40 years.
- Effects of 2-weeks Fructose & HFCS Consumption on Dyslipidemia & Insulin Resistance.
Glucose; Fructose; High-Fructose Corn Syrup; No sugar (Aspartame)

Metabolic Syndrome Clinical Trial using vitamin D3 (cholecalciferol)

Allina Health System - Recruiting 18 years or older.
- Randomized, Controlled Trial of Vitamin D Replenishment in Metabolic Syndrome.
vitamin D3 (cholecalciferol)

Type 2 Diabetes Mellitus Clinical Trial using Pistachios; control diet

Institut Investigacio Sanitaria Pere Virgili - Recruiting 25 years to 65 years.
- Effect of Pistachio Intake on Insulin Resistance and Type 2 Diabetes Mellitus.
Pistachios; control diet

Insulin Resistance, Diabetes, or End Stage Renal Disease Clinical Trial

IRCCS Policlinico S. Matteo - Recruiting 18 years to 70 years.
- Insulin Resistance And End Stage Renal Disease: The Role Of Retinol Binding Protein 4.

Obesity Clinical Trial using Exercise Group; Health Education Group

University of Pittsburgh - Recruiting 60 years to 75 years.
- Muscle Lipid and Insulin Resistance in the Elderly.
Exercise Group; Health Education Group

Hypertension, Insulin Resistance, or Dyslipidemia Clinical Trial using Telmisartan

Stanford University - Recruiting 10 years to 18 years.
- Randomized, Placebo Controlled, Double Blind Trial of Telmisartan in Hypertensive, Obese Adolescents.
Telmisartan

Hepatitis C, or Hepatitis B Clinical Trial using Pegasys; Copegus.

University Health Network, Toronto - Recruiting 18 years to 85 years.
- Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Anti-Viral Therapy.
Pegasys; Copegus.