46 results found.

Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer, or Clinical Trial using cabozantinib-s-malate; sunitinib malate; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Randomized Phase II Study Comparing Cabozantinib With Commercially Supplied Sunitinib in Patients With Previously Untreated Locally Advanced or Metastatic Renal Cell Carcinoma.
cabozantinib-s-malate; sunitinib malate; laboratory biomarker analysis

Kidney Cancer Clinical Trial using Percutaneous Optical Biopsy (OCT and DRS)

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years or older.
- Optical Biopsy to Improve the Diagnosis of Kidney Cancer: a Prospective, Observational, Multicentre, In-vivo Study.
Percutaneous Optical Biopsy (OCT and DRS)

Distal Urethral Cancer, Metastatic Transitional Cell Cancer of th Clinical Trial using eribulin mesylate; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I/II Study of E7389 Halichondrin B Analog (NSC # 707389) in Metastatic Urothelial Tract Cancer and Renal Insufficiency.
eribulin mesylate; laboratory biomarker analysis; pharmacological study

Kidney Cancer Clinical Trial using everolimus; placebo

Southwest Oncology Group - Recruiting 18 years or older.
- EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study.
everolimus; placebo

Kidney Cancer Clinical Trial using Contrast Enhanced Intraoperative Ultrasound; DEFINITY; Phone Call

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Feasibility Study of Contrast Enhanced Intraoperative Ultrasound for Detection and Characterization of Renal Mass Undergoing Open Partial Nephrectomy.
Contrast Enhanced Intraoperative Ultrasound; DEFINITY; Phone Call

Renal Cancer, or Von Hippel Lindau Clinical Trial using ZACTIMA (Vandetanib) (ZD6474)

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase 2 Study of ZD6474 (Vandetanib) in Patients With Von Hippel Lindau Disease and Renal Tumors.
ZACTIMA (Vandetanib) (ZD6474)

Syndrome Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- The Birt Hogg-Dube Syndrome: Identification of the Disease Gene and Characterization of the Predisposition of Renal Cancer.

Lung or Prostatic Neoplasms, Colorectal or Kidney Neoplasms, Panc Clinical Trial using NK cells +CliniMACs CD3 and CD56 systems

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity With Bortezomib.
NK cells +CliniMACs CD3 and CD56 systems

Renal Cell Carcinoma, Graft-Versus-Host Disease, or Engraftment S Clinical Trial using Pentostatin; Sirolimus; Cyclophosphamide; Allogeneic Hematopoietic Stem Cell Transplant; Th2 Cell Transplantation; Th2 Cells in Allogeneic HSCT

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 75 years.
- Low Intensity Allogeneic Hematopoietic Stem Cell Transplantation Therapy of Metastatic Renal Cell Carcinoma Using Early and Multiple Donor Lymphocyte Infusions Consisting of Sirolimus-Generated Donor Th2 Cells.
Pentostatin; Sirolimus; Cyclophosphamide; Allogeneic Hematopoietic Stem Cell Transplant; Th2 Cell Transplantation; Th2 Cells in Allogeneic HSCT

Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, or Cancer Clinical Trial using Laser-Assisted Angle Selection System; Block-Assisted Angle Selection System

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy.
Laser-Assisted Angle Selection System; Block-Assisted Angle Selection System

Renal Cell Carcinoma Clinical Trial using Bevacizumab; Ixempra (Ixbepilone [BMS-247550]

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase II Multi-Center Study of Bevacizumab in Combination With Ixabepilone in Subjects With Advanced Renal Cell Carcinoma.
Bevacizumab; Ixempra (Ixbepilone [BMS-247550]

Clear Cell Renal Cell Carcinoma, or Stage IV Renal Cell Cancer Clinical Trial using entinostat; aldesleukin; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18; positron emission tomography; computed tomography

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase I/II Study of High Dose Interleukin 2, Aldesleukin, in Combination With the Histone Deacetylase Inhibitor Entinostat in Patients With Metastatic Renal Cell Carcinoma.
entinostat; aldesleukin; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18; positron emission tomography; computed tomography

Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Sta Clinical Trial using bevacizumab; anti-endoglin monoclonal antibody TRC105; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Study of Bevacizumab Alone or in Combination With TRC 105 for Advanced Renal Cell Cancer.
bevacizumab; anti-endoglin monoclonal antibody TRC105; laboratory biomarker analysis; pharmacological study

Kidney Neoplasms Clinical Trial using Sunitinib malate; Placebo

Pfizer - Recruiting 18 years or older.
- Sunitinib Treatment Of Renal Adjuvant Cancer (S-TRAC): A Randomized Double Blind Phase 3 Study Of Adjuvant Sunitinib VS. Placebo In Subjects At High Risk Of Recurrent RCC.
Sunitinib malate; Placebo

Renal Impairment, Kidney Diseases, Urologic Diseases, Cancer, Hyp Clinical Trial using Renal hypothermia

Ottawa Hospital Research Institute - Recruiting 18 years or older.
- A Randomized Controlled Trial of Renal Hypothermia During Partial Nephrectomy.
Renal hypothermia

Kidney Cancer Clinical Trial using stereotactic radiosurgery; Renal Biopsy; Serum Blood Markers

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- Evaluation of a Radio-Surgical Approach for the Treatment of Kidney Tumors in Poor Surgical Candidates.
stereotactic radiosurgery; Renal Biopsy; Serum Blood Markers

Adult Primary Liver Cancer, or Kidney Tumor Clinical Trial using ultrasound elasticity imaging

Stanford University - Recruiting 19 years or older.
- US Elastography for Characterizing Focal Lesions in the Liver and Kidney.
ultrasound elasticity imaging

Cancer of Kidney and Renal Pelvis, or Cancer of Liver Clinical Trial using Dexmedetomidine

Uppsala University Hospital - Recruiting 18 years to 80 years.
- Effects of Dexmedetomidine on Periprocedural Pain During Radiofrequency Ablation of Liver and Kidney Tumours.
Dexmedetomidine

Hepatic Complications, Renal Failure, or Unspecified Adult Solid Clinical Trial using dabrafenib; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 and Pharmacokinetic Study of Dabrafenib (GSK2118436B) in Patients With BRAFV600X Mutations and Renal or Hepatic Dysfunction.
dabrafenib; pharmacological study; laboratory biomarker analysis

Prostate Cancer Clinical Trial

Yonsei University - Recruiting 20 years to 85 years.
- .

Clear Cell Renal Cell Carcinoma, Stage I Renal Cell Cancer, Stage Clinical Trial using pazopanib hydrochloride; therapeutic conventional surgery

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Pazopanib to Enable Partial Nephrectomy.
pazopanib hydrochloride; therapeutic conventional surgery

Leiomyomatosis, or Kidney Neoplasms Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene and Characterization of the Predisposition to Renal Cancer.

Kidney Cancer Clinical Trial using Contrast-enhanced Ultrasound; Perflutren lipid

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- LCCC 1219: A Prospective Pilot Study Evaluating Renal Lesions Through Contrast-enhanced US in Patients With Renal Cancer and in Those With a Risk Factor for Renal Malignancy.
Contrast-enhanced Ultrasound; Perflutren lipid

Kidney Cancer Clinical Trial using aldesleukin; bevacizumab

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Study of Bevacizumab and Aldesleukin in Patients With Metastatic Renal Cell Carcinoma (RCC): A Cytokine Working Group (CWG) Study.
aldesleukin; bevacizumab

Kidney Cancer Clinical Trial using sunitinib malate; gene expression analysis; reverse transcriptase-polymerase chain reaction; western blotting; immunohistochemistry staining method; laboratory biomarker analysis; adjuvant therapy; neoadjuvant therapy; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Biomarkers of Tumor Angiogenesis and Response to Sunitinib Maleate in Renal Cell Carcinoma.
sunitinib malate; gene expression analysis; reverse transcriptase-polymerase chain reaction; western blotting; immunohistochemistry staining method; laboratory biomarker analysis; adjuvant therapy; neoadjuvant therapy; therapeutic conventional surgery

Kidney Cancer Clinical Trial using motexafin gadolinium; sunitinib malate; comparative genomic hybridization; gene expression analysis; mutation analysis; polymorphism analysis; immunohistochemistry staining method; iodine I-124 girentuximab; laboratory biomarker analysis; pharmacological study; adjuvant therapy; neoadjuvant therapy; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Histopathologic and Imaging Study of Renal Cell Carcinoma Vasculature in the Setting of Sunitinib Therapy Prior to Cytoreductive Nephrectomy.
motexafin gadolinium; sunitinib malate; comparative genomic hybridization; gene expression analysis; mutation analysis; polymorphism analysis; immunohistochemistry staining method; iodine I-124 girentuximab; laboratory biomarker analysis; pharmacological study; adjuvant therapy; neoadjuvant therapy; therapeutic conventional surgery

Renal Cell Cancer Metastatic, or Kidney Cancer Metastatic Clinical Trial using Interleukin-2

Western Regional Medical Center - Recruiting 18 years or older.
- Phase II Trial of Moderate Dose Bolus Interleukin-2 in Metastatic Kidney Cancer.
Interleukin-2

Kidney Cancer Clinical Trial using Pazopanib; Temsirolimus; Quality of Life Assessment; Benadryl

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Randomized Phase 2 Trial of Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma.
Pazopanib; Temsirolimus; Quality of Life Assessment; Benadryl

Recurrent Renal Cell Cancer, Stage I Renal Cell Cancer, or Stage Clinical Trial using fluorescence imaging; laparoscopic surgery; indocyanine green

City of Hope Medical Center - Recruiting 18 years or older.
- A Prospective Investigation of the Use of the Fluorescence Imaging on the da Vinci Surgical System for Intraoperative Near Infrared Imaging of Renal Cortical Tumors.
fluorescence imaging; laparoscopic surgery; indocyanine green

Kidney Cancer Clinical Trial using Bevacizumab; Temsirolimus

Hellenic Cooperative Oncology Group - Recruiting 18 years or older.
- Phase II Study of Efficacy and Safety of Bevacizumab in Combination With Temsirolimus, After 1st Line Anti-VEGF Treatment in Patients With Advanced Renal Cancer.
Bevacizumab; Temsirolimus

Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Sta Clinical Trial using ziv-aflibercept; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase II Study to Determine the Effect of 2 Different Doses AVE0005 (VEGF Trap) in Patients With Metastatic Renal Cell Carcinoma.
ziv-aflibercept; laboratory biomarker analysis

Advanced Solid Tumors, Kidney Disease, or Renal Impairment Clinical Trial using AMG 386 + Paclitaxel; AMG 386

Amgen - Recruiting 18 years or older.
- An Open-label Pharmacokinetic Study of AMG 386 in Advanced Cancer Subjects With Normal and Impaired Renal Function.
AMG 386 + Paclitaxel; AMG 386

Kidney Cancer Clinical Trial using Pazopanib; Bevacizumab; Everolimus

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial.
Pazopanib; Bevacizumab; Everolimus

Kidney Cancer Clinical Trial using Evaluation

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Phase II Metastasectomy Study for Patients With Renal Cell Carcinoma..
Evaluation

Chemotherapeutic Agent Toxicity, Sarcoma, or Unspecified Childhoo Clinical Trial using gene expression analysis; polymorphism analysis; management of therapy complications

National Cancer Institute (NCI) - Recruiting N/A to 20 years.
- CYP3A5 Genotype as a Potential Risk Factor for the Development of Ifosamide Nephrotoxicity in Children.
gene expression analysis; polymorphism analysis; management of therapy complications

Recurrent Renal Cell Cancer, or Stage IV Renal Cell Cancer Clinical Trial using stereotactic body radiation therapy; therapeutic conventional surgery; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Immunologic Impact of Stereotactic Body Radiation Therapy (SBRT) in Renal Cell Carcinoma.
stereotactic body radiation therapy; therapeutic conventional surgery; laboratory biomarker analysis

Kidney Cancer Clinical Trial using gene expression analysis; protein expression analysis; diagnostic laboratory biomarker analysis; immunoenzyme technique; immunohistochemistry staining method

City of Hope Medical Center - Recruiting N/A or older.
- Development of a Blood Test of Anti-IMP3 Autoantibody for the Detection of Renal Cell Carcinoma With Metastasis and Metastatic Potential.
gene expression analysis; protein expression analysis; diagnostic laboratory biomarker analysis; immunoenzyme technique; immunohistochemistry staining method

Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma Clinical Trial using laboratory biomarker analysis; cytology specimen collection procedure

Children's Oncology Group - Recruiting N/A to 29 years.
- Renal Tumors Classification, Biology, and Banking Study.
laboratory biomarker analysis; cytology specimen collection procedure

Kidney Cancer Clinical Trial using Voluven (Hydroxyethyl starch 130/0,4); Sodium Chloride 9mg/ml

Regional Hospital Holstebro - Recruiting 18 years or older.
- Effect of Hydroxyethyl Starch on Renal Handling of Salt and Water, Blood Pressure-regulating Hormones, Proteins and Circulatory System of Patients Undergoing Kidney Removal by Keyhole Surgery.
Voluven (Hydroxyethyl starch 130/0,4); Sodium Chloride 9mg/ml

Metastatic Melanoma, or Renal Cell Cancer Clinical Trial using aldesleukin

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Studies on the Mechanism of Action of High-Dose IL-2 in Metastatic Melanoma and Renal Cell Cancer.
aldesleukin

Kidney Cancer Clinical Trial using everolimus

Baylor College of Medicine - Recruiting 18 years or older.
- Neoadjuvant Everolimus(RAD001)for Advanced RCC Before Cytoreductive Nephrectomy, With Correlative Tumor Studies (Protocol #: 06-08-20-01).
everolimus

Renal Cell Carcinoma, Kidney Neoplasm, Renal Cancer, or Kidney Ca Clinical Trial using Yttrium-90 conjugated chimeric G250 (90Y-cG250)

Ludwig Institute for Cancer Research - Recruiting N/A or older.
- Cohort Study of Increasing Doses of Yttrium-90 Conjugated to Chimeric Monoclonal Antibody cG250 (90Y-DOTA-cG250) in Patients With Advanced Renal Cancer.
Yttrium-90 conjugated chimeric G250 (90Y-cG250)

Cervical Cancer, Hpv, or Warts Clinical Trial using Quadrivalent HPV for types 6, 11, 16 and 18

Medstar Research Institute - Recruiting 9 years to 17 years.
- Immunogenicity Of A Prophylactic Quadrivalent Human Papillomavirus (Types 6, 11, 16, And 18) L1 Virus-Like Particle Vaccine In Male And Female Adolescent Transplant Recipients..
Quadrivalent HPV for types 6, 11, 16 and 18

Carcinoma, Renal Cell Clinical Trial using Radiofrequency ablation; Interferon-alpha; Radiofrequency ablation; Sunitinib maleate; Sunitinib maleate

Kidney Cancer Research Bureau - Recruiting 18 years to 85 years.
- Phase II Trial of Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients With Small Primary Tumor.
Radiofrequency ablation; Interferon-alpha; Radiofrequency ablation; Sunitinib maleate; Sunitinib maleate

Kidney Cancer, or Metastatic Cancer Clinical Trial using sunitinib malate

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Study, Multicenter, Open-label, Evaluating Efficacy of Treatment With Sutentr (Sunitinib) in Patients With Previously Untreated or Recurrent Brain Metastases Originating From Renal Cancer.
sunitinib malate

Kidney Cancer Clinical Trial using therapeutic allogeneic lymphocytes; cyclophosphamide; cyclosporine; fludarabine phosphate; allogeneic bone marrow transplantation; peripheral blood stem cell transplantation

National Cancer Institute (NCI) - Recruiting 18 years to 65 years.
- Phase II Trial in Intrafamilial Allogeneic Cell Transplant in Patients With Metastatic Kidney Cancer.
therapeutic allogeneic lymphocytes; cyclophosphamide; cyclosporine; fludarabine phosphate; allogeneic bone marrow transplantation; peripheral blood stem cell transplantation