Smith & Nephew, Inc. - Recruiting 40 years to 75 years. - PATIENT-MATCHED INSTRUMENTATION Versus (vs) STANDARD INSTRUMENTATION: A RANDOMIZED CLINICAL TRIAL COMPARING POSTOPERATIVE AXIAL ALIGNMENT and COMPONENT POSITION.
Carbylan BioSurgery, Inc. - Recruiting 40 years to 85 years. - A Multi-center, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Hydros and Hydros-TA Joint Therapies for Management of Pain Associated With Osteoarthritis in the Knee.
OrthoTrophix, Inc - Recruiting 25 years to 75 years. - A Randomized, Double-blind, Placebo-controlled, Multi-dose Phase 2 Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees.
Techfields Pharma Co. Ltd - Recruiting 35 years to 85 years. - A Phase 2, Multicenter, Randomized, Double Blind, Placebo Controlled, Parallel Group, Dose Range Finding Study to Evaluate the Efficacy and Safety of X0002 Spray Versus Placebo in Subjects With Osteoarthritis.
Seikagaku Corporation - Recruiting 40 years to 80 years. - A Multi-Center, Randomized, Double-Blind, Phosphate Buffered Saline-Controlled Study to Evaluate Effectiveness and Safety of a Single Intra-Articular Injection of Gel-Oner for the Treatment of Osteoarthritis of the Knee With Open-Label Safety Extension.
Smith & Nephew, Inc. - Recruiting N/A or older. - A Retro-Prospective, Non-randomized, Consecutive Series, SIngle Cohort, Multicenter Adaptive Design Study to Evaluate the Outcomes of Total Knee Arthroplasty (TKA) Using JOURNEYT II BCS TotaL Knee SystEm (The NIMBLE Study).
Hvidovre University Hospital - Recruiting 18 years or older. - Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties. A Randomized Controlled Trial Evaluating Early Component Migration by RSA and Patient Reported Outcome..
Charite University, Berlin, Germany - Recruiting 40 years to 70 years. - The CARAKA-Trial: Complex Ayurvedic Treatment in Osteoarthritis of the Knee Against Standard Care.A Multicentre, Randomized, Controlled Clinical Trial Based on Traditional Ayurveda-Diagnosis..
University of California, San Francisco - Recruiting 18 years to 80 years. - Quantifications of Biochemical Changes of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection Using Novel MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) Techniques.
Ampio Pharmaceuticals. Inc. - Recruiting 35 years to 85 years. - A Phase 3 Randomized, Placebo-controlled, Double-blind Study to Evaluate the Safety and Efficacy of a Single Intra-articular Injection of AmpionTM (<5 Kilodalton Ultrafiltrate of 5% Human Serum Albumin) in Adults With Pain Due to Osteoarthritis (OA) of the Knee.
Regenerative Sciences, LLC - Recruiting 18 years to 70 years. - A Randomized Controlled Trial of RegenexxT SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to Total Knee Arthroplasty.
IRCCS Policlinico S. Matteo - Recruiting 60 years or older. - A COMPARATIVE STUDY BETWEEN TWO PHARMACOLOGICAL ASSOCIATIONS OXYCODONE/NALOXONE AND CODEINE / PARACETAMOL IN TREATMENT OF MODERATE-SEVERE CHRONIC PAIN DUE TO OSTEOARTHRITIS OF KNEE AND/OR HIP.
Nantes University Hospital - Recruiting 18 years or older. - Regenerative Medicine of Articular Cartilage: Characterization and Comparison of Chondrogenic Potential and Immunomodulatory Adult Mesenchymal Stem Cells.
Anika Therapeutics, Inc. - Recruiting 40 years to 75 years. - A Randomized, Double-Blind, Placebo Controlled, Multi-Center Study of a Single Injection Cross-Linked Sodium Hyaluronate Combined With Triamcinolone Hexacetonide (Cingal) to Provide Symptomatic Relief of Osteoarthritis of the Knee.
Apimeds, Inc. - Recruiting 30 years to 85 years. - A Multicenter, Randomized, Double Blind, Active Controlled, Parallel Group, Clinical Study, to Evaluate the Safety and Efficacy of Apitox vs Histamine in Subjects With Refractory Osteoarthritis Pain and Inflammation of the Knee.
Apitox, purified honeybee toxin, lyophilized in saline; histamine
The Cleveland Clinic - Recruiting 21 years or older. - Investigating the Efficacy of Synvisc-Oner (Hylan G-F 20) as Adjunctive Therapy for Patients With Knee Osteoarthritis (OA) Requiring Physical Therapy.
Nantes University Hospital - Recruiting 18 years or older. - Medico-economic Interest of the Patient Matched Cutting Blocks (Ancillary) MyKnee r LBS During the Poses of Complete Prosthesis of Knee GMK r. Multicentric, Prospective, Controlled, Opened, Randomised Study About a Medical Device..
the prosthesis GMK r without the ancillary MyKnee r LBS; Matched patient cutting blocks MyKnee r LBS
Hanlim Pharm. Co., Ltd. - Recruiting 35 years to 75 years. - For 12 Weeks, the Multi-center, Randomized, Double-blinded, Clinical Study to Evaluate the Efficacy and Safety of Entelon Tab. 150mg Compared With Celebrex Capsule in Patients With Osteoarthritis of Knee (Phase III).
Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks; Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks; Placebo
Hospital de Clinicas de Porto Alegre - Recruiting 18 years or older. - Effect of Transcranial Direct Current Stimulation and Electro Acupuncture in Pain, Functional Capability and Cortical Excitability in Patients With Osteoarthritis..
tDCS and EAC sham; tDCS sham and EAC sham; tDCS sham and EAC; tDCS and EAC
DongGuk University - Recruiting 20 years to 80 years. - Clinical Trial to Evaluate and Compare the Efficacy and Safety of Individualized and Standardized Acupuncture for Knee Osteoarthritis Patients: Randomized, Single-blind, Controlled Study.
University of Zurich - Recruiting 60 years to 85 years. - Effect of Pre-surgery Neuromuscular Physiotherapy (PT) on Functional Outcome After Total Knee Replacement (TKR): A Single-blinded Randomized Controlled Trial..
preoperative neuromuscular training; knee OA School
University of Sao Paulo General Hospital - Recruiting 45 years to 80 years. - Prospective And Randomized Study Evaluating Tthe Effect Of The Association Of Triamcinolone To The Viscosupplementation Of The Knee.
University Hospitals of Cleveland - Recruiting 45 years or older. - A Double-Blind, Placebo-Controlled, Randomized, Crossover Pilot Study of the Efficacy of Celecoxib 200 mg QD in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee..
University Hospitals of Cleveland - Recruiting 45 years to 85 years. - A Double-Blind, Placebo-Controlled, Crossover Pilot Study of the Efficacy of Celecoxib 200 Mg Qd in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee.