31 results found.

Renal Function, or Liver Transplantation Clinical Trial using living donor liver transplantation

Samsung Medical Center - Recruiting 20 years to 70 years.
- Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Liver Transplantation.
living donor liver transplantation

Carcinoma, Hepatocellular Clinical Trial using Everolimus; Tacrolimus; Myfortic; CellCept

Baylor Research Institute - Recruiting 18 years or older.
- A 36 Month Multi-center, Open Label, Randomized, Comparator Study to Evaluate the Efficacy and Safety of Everolimus Immunosuppression Treatment in Liver Transplantation for Hepatocellular Carcinoma Exceeding Milan Criteria.
Everolimus; Tacrolimus; Myfortic; CellCept

Heart Transplantation, Kidney Transplantation, Liver Transplantat Clinical Trial

Genentech - Recruiting N/A or older.
- The Mycophenolate Pregnancy Registry.

Renal Function, or Liver Transplant Clinical Trial using Introduction of everolimus with reduced cyclosporine or tacrolimus dose, the earliest 1 month and the latest 6 months after liver transplantation.

Novartis - Recruiting 1 Month to 17 years.
- A 24-month, Multi-center, Single Arm, Prospective Study to Evaluate Renal Function, Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients..
Introduction of everolimus with reduced cyclosporine or tacrolimus dose, the earliest 1 month and the latest 6 months after liver transplantation.

Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, or Clinical Trial using donor pain management/ Pre-operative OR Set-up

Northwestern University - Recruiting 21 years to 60 years.
- A2ALL-Patients Safety System Improvements in Living Donor Liver Transplant.
donor pain management/ Pre-operative OR Set-up

De Novo Autoimmune Hepatitis Clinical Trial using Pediatric transplant subject with d-AIH; Pediatric transplant subject with acute rejection; Pediatric transplant subject with chronic rejection; Adult non-transplant patients with auto-immune hepatitis; Adult non-transplant subjects with chronic hepatitis C virus; Pediatric control subjects

Yale University - Recruiting 3 Months to 50 years.
- De Novo Autoimmune Hepatitis in Pediatric Liver Transplantation.
Pediatric transplant subject with d-AIH; Pediatric transplant subject with acute rejection; Pediatric transplant subject with chronic rejection; Adult non-transplant patients with auto-immune hepatitis; Adult non-transplant subjects with chronic hepatitis C virus; Pediatric control subjects

Acute Kidney Injury Clinical Trial

Universitaire Ziekenhuizen Leuven - Recruiting 18 years or older.
- The Role of Biomarkers in the Early Detection of Acute Kidney Injury Induced by Liver Transplantation : an Observational Analysis..

Liver Transplantation, Hyperglycemia, or Rejection Clinical Trial using Insulin

Northwestern University - Recruiting 18 years to 80 years.
- Prospective, Randomized, Open-Label, Controlled Study to Evaluate the Safety and Efficacy of Intensive Glycemic Control on Outcomes Following Liver Transplantation.
Insulin

Hepatitis B, Cirrhosis, or Awaiting Organ Transplant Clinical Trial using HBV vaccine

Fundaci¢n P£blica Andaluza para la gesti¢n de la Investigaci¢n en Sevilla - Recruiting 18 years to 65 years.
- Open-label, Phase III, Randomized, Clinical Trial to Evaluate the Efficacy of Two Different Hepatitis B Virus (HBV) Vaccination Schemes in Patients With Hepatic Cirrhosis Candidates to Liver Transplantation.
HBV vaccine

Liver Transplantation Clinical Trial using Everolimus + reduced tacrolimus; Standard tacrolimus

Novartis - Recruiting 18 years or older.
- A 24 Month, Randomized, Controlled, Study to Evaluate the Efficacy and Safety of Concentration-controlled Everolimus Plus Reduced Tacrolimus Compared to Standard Tacrolimus in Recipients of Living Donor Liver Transplants.
Everolimus + reduced tacrolimus; Standard tacrolimus

Liver Transplantation, or Kidney Transplantation Clinical Trial using rTPA Treatment

The Cleveland Clinic - Recruiting 18 years or older.
- Enhancing DCD Utilization With Thrombolytic Therapy.
rTPA Treatment

Cholangiocarcinoma Clinical Trial using Observation data collection study.

Washington University School of Medicine - Recruiting 18 years to 70 years.
- Prospective Registry Study of Neoadjuvant Chemoradiation in Conjunction With Liver Transplantation for Cholangiocarcinoma With Induction Gemcitabine, Followed by 3D Conformal Radiation With 5-FU as a Radiosensitizer, and Maintenance Xeloda Therapy Until Liver Transplantation.
Observation data collection study.

Side Effects of Calcineurin Inhibitors, Renal Toxicity, Hepatic F Clinical Trial using Liver biopsy

Thomas Jefferson University - Recruiting 18 years or older.
- Sirolimus Switching From Calcinurin Inhibitors (CNI) 90 - 180 Days After Liver Transplantation.
Liver biopsy

Islet Transplantation in Diabetes Mellitus Type 1, Clinical Trial using Reparixin; Placebo

Domp‚ s.p.a. - Recruiting 18 years to 70 years.
- A Phase 3, Multicenter, Randomized, Double-blind, Parallel Assignment Study to Assess the Efficacy and Safety of Reparixin in Pancreatic Islet Transplantation.
Reparixin; Placebo

Liver Cirrhosis Clinical Trial

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico - Recruiting 18 years to 65 years.
- Insulin Secretion and Sensitivity in Subjects With Liver Cirrhosis Undergoing Orthotopic Liver Transplantation (OLT): Pre- and Post-OLT Analysis.

Liver Transplantation Clinical Trial using MultiStem

University Hospital Regensburg - Recruiting 18 years to 65 years.
- Safety and Feasibility of Multipotent Adult Progenitor Cells for Immunomodulation Therapy After Liver Transplantation: A Phase I Study of the MiSOT Study Consortium.
MultiStem

Chronic Hepatitis C Clinical Trial using Sofosbuvir; RBV; PEG

Gilead Sciences - Recruiting 18 years or older.
- An Open-Label Study of GS-7977 + Ribavirin With or Without Peginterferon Alfa-2a in Subjects With Chronic HCV Infection Who Participated in Prior Gilead HCV Studies.
Sofosbuvir; RBV; PEG

Hepatitis C, Chronic Clinical Trial using Simprenavir; Daclatasvir; Ribavarin

Janssen R&D Ireland - Recruiting 18 years or older.
- Phase 2, Open-Label Study to Investigate the Pharmacokinetics, Efficacy, Safety, and Tolerability of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052) and Ribavirin (RBV) in Subjects With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation.
Simprenavir; Daclatasvir; Ribavarin

Kidney Transplantation, Liver Transplantation, Heart Transplantat Clinical Trial using Advagraf; Prograf

Astellas Pharma Inc - Recruiting 5 years to 16 years.
- A Phase II, Open-Label, Multi-Center Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From a Prografr Based Immunosuppressive Regimen to a Tacrolimus Prolonged Release, Advagrafr Based Immunosuppressive Regimen, Including a Long-Term Follow-Up.
Advagraf; Prograf

Evidence of Liver Transplantation Clinical Trial

Chang Gung Memorial Hospital - Recruiting 20 years or older.
- Trends of Immunosuppression Therapy and Their Effectiveness in Patients With Liver Transplantation.

Hepatocellular Carcinoma Clinical Trial using Sirolimus; m-TOR inhibitor free

Seoul National University Hospital - Recruiting 18 years to 80 years.
- A Randomized Phase ?, Trial With Sirolimus-containing Versus mTOR-inhibitor Free Immunosuppression in Patients Undergoing Living Donor Liver Transplantation for Hepatocellular Carcinoma Exceeding Milan Criteria.
Sirolimus; m-TOR inhibitor free

Hepatocellular Carcinoma Clinical Trial using COMBIG-DC

Immunicum AB - Recruiting 18 years or older.
- A Phase I Open-label Study to Evaluate Safety and Immunologic Response of COMBIG-DC Administered Intra-tumorally in Patients With Hepatocellular Carcinoma.
COMBIG-DC

Early Allograft Dysfunction, Ischemic Reperfusion Injury, Liver T Clinical Trial using Tacrolimus

Republican Scientific and Practical Center for Organ and Tissue Transplantation - Recruiting 18 years to 69 years.
- A Randomized Study of Effect of Preimplantation Portal Vein and Hepatic Artery Liver Flushing With Tacrolimus on Ischemia-reperfusion Injury, Allograft Dysfunction and Liver Histology.
Tacrolimus

Childhood Hepatoblastoma, Stage I Childhood Liver Cancer, Stage I Clinical Trial using therapeutic conventional surgery; cisplatin; fluorouracil; vincristine sulfate; doxorubicin hydrochloride; irinotecan hydrochloride; liver transplantation; laboratory biomarker analysis

Children's Oncology Group - Recruiting N/A to 21 years.
- Treatment of Children With All Stages of Hepatoblastoma.
therapeutic conventional surgery; cisplatin; fluorouracil; vincristine sulfate; doxorubicin hydrochloride; irinotecan hydrochloride; liver transplantation; laboratory biomarker analysis

Kidney Transplantation, or Liver Transplantation Clinical Trial using Prevenar13; Pneumovax

Helsinki University Central Hospital - Recruiting 18 years to 70 years.
- Immunogenicity of Repeated Dose 13-valent Pneumococcal Conjugate Vaccine Compared to the Existing Recommended Protocol of Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients.
Prevenar13; Pneumovax

Phenylketonuria Clinical Trial using Preparative Radiation Therapy; Hepatocyte Transplant; Immunosuppression; Liver Evaluation

University of Pittsburgh - Recruiting 18 years or older.
- Hepatocyte Transplantation for Phenylketonuria.
Preparative Radiation Therapy; Hepatocyte Transplant; Immunosuppression; Liver Evaluation

Liver Damage Clinical Trial using The Medtronic Portable Bypass System (PBSr)

Columbia University - Recruiting 18 years to 90 years.
- Hypothermic Machine Preservation of Extended Criteria Liver Allografts for Transplantation.
The Medtronic Portable Bypass System (PBSr)

Hepatocellular Carcinoma Clinical Trial using LC Bead loaded with doxorubicin

University of Pittsburgh - Recruiting 18 years or older.
- LC Drug Eluting Bead for Regional Chemoembolization to Downstage Unresectable Hepatocellular Carcinoma (HCC) to Liver Transplantation.
LC Bead loaded with doxorubicin

Liver Cirrhosis Clinical Trial using Plasma pheresis, Right portal vein embolization

Seoul National University Hospital - Recruiting 20 years to 70 years.
- Evaluation of Liver Regeneration With Autologous Peripheral Stem Cells Transplantation in the Patient Needed Extensive Hepatectomy.
Plasma pheresis, Right portal vein embolization

Liver Transplantation, or Fungal Infection Clinical Trial using Caspofungin

Grupo de Estudio de Infecciones en Transplantados - Recruiting 18 years or older.
- Prophylaxis With Caspofungin for the Prevention of Invasive Fungal Infections in High-Risk Liver Transplant Recipients.
Caspofungin