Hoffmann-La Roche - Recruiting 18 years to 65 years. - A Multi Center, Randomized, Double-blind, Placebo Controlled, Parallel-group Study to Investigate the Efficacy and Safety of RO4995819 Versus Placebo, as Adjunctive Therapy in Patients With Major Depressive Disorder Having Inadequate Response to Ongoing Antidepressant Treatment (ARTDeCo).
National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years. - An Investigation to Determine Whether Levels of P11 Protein in Peripheral Blood Cells Correlate With Treatment Response to Citalopram in Patients With Major Depressive Disorder.
Genomind, LLC - Recruiting 18 years to 65 years. - A Six-month Study of the Genecept Assay vs. Treatment as Usual to Evaluate Efficacy of Using Assay Guided Treatment in Outpatient Adults With Treatment Resistant Depression.
Karolinska Institutet - Recruiting 18 years to 65 years. - Cognitive Behavior Therapy Versus a Return to Work Intervention for Sick-listed Patients With Subclinical Common Mental Illness in Primary Care: a Randomized Controlled Trial.
University of Sao Paulo - Recruiting 18 years to 75 years. - Escitalopram and Transcranial Direct Current Stimulation in Major Depressive Disorder: a Double-blind, Placebo-controlled, Randomized, Non-inferiority Trial.
Escitalopram oxalate; transcranial direct current stimulation
Cervel Neurotech, Inc. - Recruiting 18 years to 70 years. - A Prospective, Double-Blind, Randomized, Parallel-Group, Sham-Controlled Feasibility Trial of Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Major Depressive Disorder.
Active Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator; Inactive Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator
Cerecor Inc - Recruiting 18 years to 70 years. - A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Study of CERC-301 in the Adjunctive Treatment of Subjects With Severe Depression and Recent Active Suicidal Ideation Despite Antidepressant Treatment.
University Hospital, Bonn - Recruiting 20 years to 75 years. - Assessment of Efficacy, Safety and Effects on Quality of Life of Deep Brain Stimulation to the Medial Forebrain Bundle in Patients With Treatment Resistant Major Depression (FORESEE II: FOREbrain Stimulation dEprEssion).
Deep Brain Stimulation with Activa PC Multi-program Neurostimulator
Karolinska Institutet - Recruiting 18 years to 65 years. - Cognitive Behavior Therapy Versus a Return to Work Intervention for Sick-listed Patients With Common Mental Illness in Primary Care: a Randomized Clinical Trial.
University of Connecticut Health Center - Recruiting 18 years or older. - A Randomized, Double-Blind Placebo-controlled Study Evaluating the Efficacy of Omega 3 Fatty Acid Augmentation of Desvenlafaxine for the Treatment of Major Depressive Disorder in Patients With Medical Illness..
University of Trier - Recruiting 18 years to 65 years. - Neuropattern - Clinical Trial of a Psychobiological Stress Diagnostic Tool (Neuropattern - Erprobung Einer Psychobiologischen Stressdiagnostik).
Stanford University - Recruiting N/A or older. - Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression.
Sheba Medical Center - Recruiting 18 years or older. - A Placebo Controlled Trial of the Dopamine D-2 Receptor Agonist Ropinirole in Treatment of 60 Patients With Refractory Bipolar I and II Depression..