National University Hospital, Singapore - Recruiting 19 years or older. - A Multicentre Randomised Study Comparing Indwelling Pleural Catheter With Talc Pleurodesis in Patients With a Malignant Pleural Effusion.
Chinese PLA General Hospital - Recruiting 18 years to 60 years. - Open-labled, Randomized, Multicenter Phase III Study of Adjuvant Chemotherapy Comparing Bevacizumab Plus Cisplatin With Cisplatin Regimen in Malignant Pleural Effusion of Advanced Stage Non-Small-Cell Lung Cancer Patients.
University of California, Davis - Recruiting 18 years or older. - TIME1: A 2 X 2 Factorial Trial to Assess Whether Non-Steroidal Anti-Inflammatory Analgesics and Small-Bore Chest Tubes Are Less Painful Than Opiate Analgesics and Large-Bore Chest Tubes in Pleurodesis for Malignant Pleural Effusion..
Large bore chest drain + NSAID based analgesic regimen; Small bore chest drain + NSAID based analgesic regimen; Large bore chest drain + opiate based analgesic regimen; Small bore chest drain + opiate based analgesic regimen