60 results found.

Breast Cancer, or Neoplasm Metastasis Clinical Trial using Standard supportive care (packed RBC transfusion); epoetin alfa + packed RBC transfusion

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Randomized, Open-label, Multicenter, Phase 3 Study of Epoetin Alfa Plus Standard Supportive Care Versus Standard Supportive Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy.
Standard supportive care (packed RBC transfusion); epoetin alfa + packed RBC transfusion

Melanoma (Skin) Clinical Trial using gene expression analysis; polymerase chain reaction; polymorphism analysis; matrix-assisted laser desorption/ionization time of flight mass spectrometry; medical chart review

Case Comprehensive Cancer Center - Recruiting N/A or older.
- Identification of Genomic Lesions Promoting Nodal Metastasis in Malignant Melanoma.
gene expression analysis; polymerase chain reaction; polymorphism analysis; matrix-assisted laser desorption/ionization time of flight mass spectrometry; medical chart review

Glioblastoma Multiforme, Squamous Cell Carcinoma of Head and Neck Clinical Trial using CC-115

Celgene Corporation - Recruiting 18 years or older.
- A Phase 1a/b, Multicenter, Open Label, Dose-Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Dual DNA-PK and TOR Kinase Inhibitor, CC-115, Administered Orally to Subjects With Advanced Solid Tumors, and Hematologic Malignancies..
CC-115

Rectal Cancer Clinical Trial using folfox; short course Radiotherapy

Yonsei University - Recruiting 18 years or older.
- A Phase 2 Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis.
folfox; short course Radiotherapy

Malignant Melanoma With Metastasis Clinical Trial using Vaccine consisting of a peptide derived from the protein IDO

Herlev Hospital - Recruiting 18 years to 80 years.
- Peptide Vaccination in Combination With Either Ipilimumab or Vemurafenib for the Treatment of Patients With Unresectable Stage III or IV Malignant Melanoma A Phase I Study (First in Man).
Vaccine consisting of a peptide derived from the protein IDO

Prostatic Neoplasms Clinical Trial using Radium-223 dichloride (Xofigo, BAY88-8223)

Bayer - Recruiting 18 years or older.
- A Single-arm, International, Prospective, Interventional, Open-label, Multicenter Study of Radium-223 Dichloride in the Treatment of Patients With Castration-Resistant Prostate Cancer (CRPC) With Bone Metastasis.
Radium-223 dichloride (Xofigo, BAY88-8223)

Colorectal Cancer, Liver Metastasis, or Colorectal Adenocarcinoma Clinical Trial using Sulindac; Placebo

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Phase 2 Prospective Randomized Double Blind Trial Comparing Metastasectomy Plus Sulindac Versus Metastasectomy Alone in Patients With Stage IV Colorectal Cancer.
Sulindac; Placebo

Brain Metastasis, or Cancer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- A Pilot Study to Evaluate Neuropsychological Outcome Measures and Their Relationship With Prognosis in Patients Receiving Radiation Therapy for Brain Metastases.

Breast Neoplasm, or Metastasis Clinical Trial using Eribulina

Medica Scientia Innovation Research - Recruiting 18 years or older.
- A Phase IIa Prospective, Multicenter, Open and Not Controlled of the Efficacy and Tolerability on the First Line Treatment With Eribulin as a Unic Agent on Patients With HER2 Negative Metastatic Breast Cancer Previously Treated With Taxanes.
Eribulina

Brain Cancer Clinical Trial using Diffusion kurtosis imaging (DKI)

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Assessment of Early Response by Diffusion Kurtosis Imaging in Patients With Brain Metastasis.
Diffusion kurtosis imaging (DKI)

Colorectal Cancer, Neoplasm Metastasis Clinical Trial using bevacizumab [Avastin]; 5-FU based doublet chemotherapy

Hoffmann-La Roche - Recruiting 18 years to 75 years.
- A Multi-center, Single-arm, Pilot Study of 5-FU Based Doublet Chemotherapy Plus Bevacizumab as Neoadjuvant Therapy for Patients With Previously Untreated Unresectable Liver-only Metastases From Colorectal Cancer.
bevacizumab [Avastin]; 5-FU based doublet chemotherapy

Bone Metastases, or Castration-Resistant Prostate Cancer Clinical Trial using Alpharadinr (Radium-223 dichloride) + docetaxel; Docetaxel

Algeta ASA - Recruiting 18 years or older.
- A Phase I/IIa Study of Safety and Efficacy of Alpharadinr With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer.
Alpharadinr (Radium-223 dichloride) + docetaxel; Docetaxel

Liver Metastasis Clinical Trial

The Leeds Teaching Hospitals NHS Trust - Recruiting 18 years or older.
- Randomised Controlled Trial of Pringle Manoeuvre Versus Portal Vein Clamping in Patients Undergoing Liver Resection for Colorectal Liver Metastasis - A Pilot Study.

Neoplasms, Neoplasm Metastasis, or Lymphoma Clinical Trial using LY3039478

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 1 Study of LY3039478 in Patients With Advanced or Metastatic Cancer.
LY3039478

Neoplasms, Neoplasm Metastasis, Melanoma, Carcinoma, Non-Small-Ce Clinical Trial using LY3009120 capsule

Eli Lilly and Company - Recruiting 18 years or older.
- A Phase 1 Study of LY3009120 in Patients With Advanced or Metastatic Cancer.
LY3009120 capsule

Neoplasm Metastasis, Thyroid Neoplasm, or Thyroid Nodule Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Studies on Thyroid Nodules and Thyroid Cancer.

Spine Metastasis Clinical Trial using SBRT; Radiosurgery

Chinese University of Hong Kong - Recruiting 18 years or older.
- Randomized Phase II Study of Image-Guided Radiosurgery / SBRT for Localized Spine Metastasis.
SBRT; Radiosurgery

Squamous-cell Cervical Carcinoma Stage IB2 to IIB Without Spread Clinical Trial using 18F-FDG-PET

Hospices Civils de Lyon - Recruiting 18 years or older.
- Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy.
18F-FDG-PET

Carcinoma, Non-Small-Cell Lung, or Neoplasm Metastasis Clinical Trial using 34 Gy in a single fraction; 54Gy 18Gy/fr. x 3 fractions; 50Gy (12 x 5 fr.s); 60Gy (7.5Gy x 8fr.)

Institut Catal… d'Oncologia - Recruiting 18 years or older.
- Risk Adapted Free Flattering Filter Based Stereotactic Ablative Radiotherapy (Sabr) in Stage i Nsclc and Lung Metastases.
34 Gy in a single fraction; 54Gy 18Gy/fr. x 3 fractions; 50Gy (12 x 5 fr.s); 60Gy (7.5Gy x 8fr.)

Metastatic Cancer Clinical Trial using conventional surgery; intraoperative radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I/II Study Utilizing the Zeiss INTRABEAM System for the Treatment of a Resected Solitary Brain Metastasis.
conventional surgery; intraoperative radiation therapy

Neoplasm Metastasis Clinical Trial using LY2940680

Eli Lilly and Company - Recruiting 20 years or older.
- A Phase 1 Study of LY2940680 in Japanese Patients With Advanced Solid Tumors.
LY2940680

Neoplasm Metastasis, or Lymphoma Clinical Trial using LY2835219

Eli Lilly and Company - Recruiting 20 years or older.
- A Phase 1 Study of LY2835219 in Japanese Patients With Advanced Cancer.
LY2835219

Non-small Cell Lung Cancer, or Metastasis From Other Cancers Clinical Trial using Stereotactic Radiation

University Health Network, Toronto - Recruiting 18 years or older.
- Lung Stereotactic Radiation Therapy for Patients With Non-small Cell Lung Cancer and Other Cancers.
Stereotactic Radiation

Brain Metastases Clinical Trial using Hypofractionated stereotactic radiotherapy

University Health Network, Toronto - Recruiting 18 years or older.
- Hypofractionated Stereotactic Radiotherapy (HF-SRT) for Large-Volume Brain Metastases.
Hypofractionated stereotactic radiotherapy

Appendix Cancer, or Colorectal Cancer Clinical Trial using Cytoreductive Surgery; HIPEC with Mitomycin-C; EPIC with FUDR and Leucovorin

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- ICARuS (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Single-center, Randomized Phase II Trial of Early Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis.
Cytoreductive Surgery; HIPEC with Mitomycin-C; EPIC with FUDR and Leucovorin

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrent Disease, Clinical Trial using BKM120

Centre Leon Berard - Recruiting 18 years or older.
- A Phase II, Multicenter Trial Aiming to Evaluate the Clinical Interest of a Monotherapy With BKM120 , a PI3K Inhibitor in Patient With Metastatic Head and Neck Cancer Recurrent or Progressive Under Platin and Cetuximab-based Chemotherapy.
BKM120

Colorectal Cancer, or Metastatic Cancer Clinical Trial using floxuridine; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Multi-Institutional Efficacy and Safety Study of Chemotherapy With Selective Internal Radiation Treatment Using Y-90 Microspheres (CHEMO-SIRT) in Patients With Colorectal Cancer Liver Metastasis.
floxuridine; fluorouracil; irinotecan hydrochloride; leucovorin calcium; oxaliplatin

Peutz-Jeghers Syndrome, Neoplastic Processes, or Neoplasm Metasta Clinical Trial using Everolimus

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years or older.
- Pilot Study of Everolimus in the Treatment of Neoplasms in Patients With Peutz-Jeghers Syndrome.
Everolimus

Colorectal Cancer Clinical Trial using two stage hepatectomy

Centre Hospitalier Universitaire, Amiens - Recruiting 18 years or older.
- Associating Liver Partition and Portal Vein Ligation (ALPPS) for Potentially Resectable Liver Metastasis From Colorectal Cancer: Prospective Evaluation of the Early Two-stage Hepatectomy by the Simon's Methods.
two stage hepatectomy

Prostate Cancer Clinical Trial using ADT Therapy; Axitinib; Prostatectomy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Pre-surgical Androgen Deprivation Therapy With or Without Axitinib in Previously Untreated Prostate Cancer Patients With Known or Suspected LymphNode Metastasis.
ADT Therapy; Axitinib; Prostatectomy

Brain Metastasis Clinical Trial using Trental; Vitamin E

University of Cincinnati - Recruiting 18 years or older.
- A Phase II Trial to Evaluate the Use of Trental and Vitamin E for Prophylaxis of Radiation Necrosis.
Trental; Vitamin E

Breast Cancer, or Brain Metastasis Clinical Trial using Radiation therapy Brain metastasis in breast cancer

Institut Paoli-Calmettes - Recruiting 18 years or older.
- Double-blind Randomized Multicenter Phase III Study Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer..
Radiation therapy Brain metastasis in breast cancer

Hepatocellular Carcinoma, Metastasis, or Invasion Clinical Trial using Colchicine

Kaohsiung Medical University Chung-Ho Memorial Hospital - Recruiting 20 years to 90 years.
- Evaluation the Potential of Colchicine for the Palliative Management of Hepatocellular Carcinoma Patients With Distant Metastasis or Large Vessel Invasion.
Colchicine

Pancreatic Adenocarcinoma, or Colorectal Cancer Clinical Trial

Oslo University Hospital - Recruiting N/A or older.
- The Process of Metastasis in Colorectal Cancer Tumour Biology and Prognostic Factors in Pancreatic Cancer.

Kidney Cancer Clinical Trial using gene expression analysis; protein expression analysis; diagnostic laboratory biomarker analysis; immunoenzyme technique; immunohistochemistry staining method

City of Hope Medical Center - Recruiting N/A or older.
- Development of a Blood Test of Anti-IMP3 Autoantibody for the Detection of Renal Cell Carcinoma With Metastasis and Metastatic Potential.
gene expression analysis; protein expression analysis; diagnostic laboratory biomarker analysis; immunoenzyme technique; immunohistochemistry staining method

Central Nervous System (CNS) Metastases, or Brain Metastases Clinical Trial using Topotecan; Temozolomide

The Methodist Hospital System - Recruiting 18 years to 79 years.
- Phase II Trial of Chemotherapy With Temozolomide in Combination With Topotecan for Central Nervous System (CNS) Metastasis of Solid Tumors.
Topotecan; Temozolomide

Neoplasm Metastasis Clinical Trial using Biopsy; Blood samples; Pharmacokinetics; Midazolam clearance test

UMC Utrecht - Recruiting 18 years or older.
- Feasibility Study of Biomarker Development for Response Prediction by Large Scale DNA Mutational Analysis of Metastatic Lesions.
Biopsy; Blood samples; Pharmacokinetics; Midazolam clearance test

Colorectal Cancer, or Metastasis Clinical Trial using Bevacizumab + blood samples

Centre Leon Berard - Recruiting 18 years or older.
- Exploration of New Biologic Factors' Predictive Value , Especially Circulating VE-cadherin in Metastatic Colorectal Adenocarcinoma Patients Treated With Bevacizumab.
Bevacizumab + blood samples

Rectal Cancer, Colon Cancer, Metastasis, or Adenocarcinoma Clinical Trial using Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Phase I/II Pharmacodynamic Study of Hydroxychloroquine in Combination With FOLFOX Plus Bevacizumab to Inhibit Autophagy in Colorectal Cancer.
Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Metastatic Castration Resistant Prostate Cancer Patients Clinical Trial using metastasis biopsy

Gustave Roussy, Cancer Campus, Grand Paris - Recruiting 18 years or older.
- Prostate Cancer Evaluation of TaRgets in Genito Urinary Screening Program.
metastasis biopsy

Colorectal and Ovarian Cancer Patients With Liver Metastasis Clinical Trial using EMD525797

Merck KGaA - Recruiting 18 years or older.
- A Phase I, Open-label, Dose-escalation Study to Investigate the Safety, Tolerability, PD and PK of EMD 525797 Using DCE-MRI as a PK Measure of Response in Colorectal and Ovarian Cancer Patients With Liver Metastases After Failure of Standard Therapy.
EMD525797

Brain Metastasis Clinical Trial using Chloroquine diphosphate

Main Line Health - Recruiting 18 years or older.
- IDO2 Genetic Status Informs the Neoadjuvant Efficacy of Chloroquine in Brain Metastasis Radiotherapy..
Chloroquine diphosphate

Brain Metastasis, or Non Small Cell Lung Cancer Clinical Trial using whole brain radiation(WBI); Icotinib

Guangdong Association of Clinical Trials - Recruiting 18 years to 75 years.
- Phase III Study of Icotinib Treat the Patient With Brain Metastasis EGFR-mutant Non Small Cell Lung Cancer Comparing With Whole Brain Radiotherapy.
whole brain radiation(WBI); Icotinib

Colorectal Neoplasms, Neoplasm Metastasis, or Liver Neoplasms Clinical Trial using Cetuximab; chemotherapy of mFOLFOX6 or FOLFIRI

Fudan University - Recruiting 18 years to 75 years.
- Study of Cetuximab in Combination With Chemotherapy for the First Treatment of Metastatic Colorectal Cancer.
Cetuximab; chemotherapy of mFOLFOX6 or FOLFIRI

Breast Cancer Clinical Trial using ultrasound imaging

Ohio State University Comprehensive Cancer Center - Recruiting 55 years or older.
- Lymph Node Evaluation in the Axilla of Symptomatic Older Women During Breast Sonography..
ultrasound imaging

Soft Tissue Sarcoma, or Lung Metastasis Clinical Trial using chest radiography; chest CT

Centre Oscar Lambret - Recruiting 18 years to 70 years.
- Phase II Study Evaluating Strategies of Lung Surveillance of Patients Operated of High Grade Soft Tissue Sarcoma: Chest Radiograph Versus Chest CT.
chest radiography; chest CT

Breast Neoplasms, Endocrine Breast Diseases, or Neoplasm Metastas Clinical Trial using letrozole; lapatinib; everolimus

University of Maryland - Recruiting 18 years or older.
- GCC 0901- A Phase II Study of Letrozole in Combination With Lapatinib Followed by an Addition of Everolimus in Postmenopausal Women With Advanced Endocrine Resistant Breast Cancer.
letrozole; lapatinib; everolimus

Colorectal Cancer With Liver Metastasis Clinical Trial using perihepatic lymphadenectomy

Gachon University Gil Medical Center - Recruiting 18 years to 80 years.
- Prospective Phase II Trial on Prophylactic Perihepatic Lymphadenectomy in Patients With Colorectal Cancer With Liver Metastasis.
perihepatic lymphadenectomy

Renal Cell Carcinoma, or Pulmonary Metastases Clinical Trial using Sunitinib; Placebo

Association of Urogenital Oncology (AUO) - Recruiting 18 years to 75 years.
- Prospektiv Randomisierte Multizentrische Phase II-Studie Zur Metastasenresektion Von Lungenfiliae (Poor-prognosis) Beim Klarzelligen Nierenzellkarzinom +/- Adjuvante Sunitinibtherapie ber 1 Jahr SMAT - AN 20/04 Der AUO.
Sunitinib; Placebo

Breast Cancer, or Neoplasm Metastasis Clinical Trial using Non pegylated liposomal doxorubicin, trastuzumab, docetaxel

Catharina Ziekenhuis Eindhoven - Recruiting 18 years or older.
- Phase II Multicentre Open Label Study Evaluating the Efficacy and Safety of Liposomal Doxorubicin, Trastuzumab, Docetaxel as First-line Treatment of Patients With HER2 Positive Metastatic Breast Cancer.
Non pegylated liposomal doxorubicin, trastuzumab, docetaxel

Endometrial Neoplasms, or Neoplasm Metastasis Clinical Trial using Tumor biopsy study

University of Bergen - Recruiting N/A or older.
- Prospective Study of Endometrial Cancer Treatment in Relation to Molecular Markers in Curettage Specimens..
Tumor biopsy study

Breast Neoplasms, or Neoplasm Metastasis Clinical Trial

Beijing Cancer Hospital - Recruiting 18 years to 75 years.
- Gene Expression Profiling of Metastatic Breast Cancer Predict the Therapeutic Response to Chemotherapy.

Clear Cell Renal Cell Carcinoma, or Metastasis Clinical Trial using Sunitinib

Korean Urological Oncology Society - Recruiting 18 years or older.
- Neoadjuvant Sunitinib Therapy in Patients With Metastatic Clear Cell Type Renal Cell Carcinoma Patients: a Prospective Study.
Sunitinib

Nonsmall Cell Lung Cancer Clinical Trial using Radiosurgery; Observation

Samsung Medical Center - Recruiting 18 years or older.
- Randomized Phase III Trial of Stereotactic Radiosurgery (SRS) Versus Observation for Patients With Asymptomatic Cerebral Oligo-metastases in Non-small Cell Lung Cancer (NSCLC).
Radiosurgery; Observation

Breast Neoplasms, Neoplasm Metastasis, Gene Expression Profiling, Clinical Trial using cytokine

Beijing Cancer Hospital - Recruiting 18 years to 75 years.
- Gene Expression Profiling of Breast Cancer Cells in Pleural Effusion Prodict the Response of Malignant Pleural Effusion to Immunotherapy.
cytokine

Brain Neoplasms, or Neoplasm Metastasis Clinical Trial using Whole brain radiation therapy arm; Salvage stereotactic radiosurgery arm

Japan Clinical Oncology Group - Recruiting 20 years to 79 years.
- Randomized Phase III Trial of Postoperative Whole Brain Radiation Therapy Compared With Salvage Stereotactic Radiosurgery in Patients With One to Four Brain Metastasis: Japan Clinical Oncology Group Study (JCOG 0504).
Whole brain radiation therapy arm; Salvage stereotactic radiosurgery arm

Breast Cancer, Prostate Cancer, Vertebral Metastasis, or Pain Clinical Trial using Vertebroplasty

McGill University Health Center - Recruiting 35 years to 75 years.
- Challenging the Paradigm in Pain Relief for Advanced Breast and Prostate Cancer Patients With Vertebral Metastasis: Vertebral Augmentation With Cement Plus Radiotherapy Versus Radiotherapy. A Randomized, Prospective, Double Blind Pilot Study.
Vertebroplasty

Cancer, Metastasis, or Pain Clinical Trial using Samarium (153SM)

New York Methodist Hospital - Recruiting 18 years to 80 years.
- Phase I/II Study of the Use of Vertebral Intracavitary Cement and Samarium (VICS) for Painful Vertebral Metastases.
Samarium (153SM)