43 results found.

Metastatic Colorectal Cancer, Metastatic Gastric Cancer, Metastat Clinical Trial using CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract Cancers.
CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

Neoplasms, Pancreas Clinical Trial using cancer stem cell vaccine

Fuda Cancer Hospital, Guangzhou - Recruiting 18 years to 75 years.
- Study of Cancer Stem Cell Vaccine That as a Specific Antigen in Metastatic Adenocarcinoma of the Pancreas.
cancer stem cell vaccine

Pancreatic Cancer Patients Diagnosed With Locally Advanced or Met Clinical Trial using L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine

Philogen S.p.A. - Recruiting 18 years to 70 years.
- Phase I Study of the Tumor-targeting Human L19IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Gemcitabine in Patients With Advanced Pancreatic Cancer.
L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Ipilimumab; Vaccine; FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase 2, Multicenter Study of FOLFIRINOX Followed by Ipilimumab in Combination With Allogeneic GM-CSF Transfected Pancreatic Tumor Vaccine (GVAX) in the Treatment of Metastatic Pancreatic Cancer.
Ipilimumab; Vaccine; FOLFIRINOX

Lung or Prostatic Neoplasms, Colorectal or Kidney Neoplasms, Panc Clinical Trial using NK cells +CliniMACs CD3 and CD56 systems

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity With Bortezomib.
NK cells +CliniMACs CD3 and CD56 systems

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Mayo Clinic - Recruiting 18 years or older.
- Phase I Trial of The Combination of Vismodegib and Sirolimus.
vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Metastatic Cancer, Pancreatic Cancer, Mesothelioma, Ovarian Cance Clinical Trial using Fludarabine; Cycolphosphamide; Aldesleukin

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-mesothelin Gene Engineered Lymphocytes.
Fludarabine; Cycolphosphamide; Aldesleukin

2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer Clinical Trial using GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Aduro BioTech, Inc. - Recruiting 18 years or older.
- A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma.
GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Metastatic Pancreatic Cancer Clinical Trial using Veliparib and 5-FU and Oxaliplatin and Leucovorin

Georgetown University - Recruiting 18 years or older.
- A Phase I/II Study of ABT-888 in Combination With 5-fluorouracil and Oxaliplatin (Modified FOLFOX-6) in Patients With Metastatic Pancreatic Cancer.
Veliparib and 5-FU and Oxaliplatin and Leucovorin

Pancreatic Cancer Clinical Trial using Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Georgetown University - Recruiting 18 years or older.
- A Pilot Study of Molecularly Tailored Therapy for Patients With Metastatic Pancreatic Cancer.
Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Gemcitabine, Dasatinib and Erlotinib in Patients With Advanced Pancreatic Carcinoma.
gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

Stage IV Pancreatic Cancer Clinical Trial using Ascorbic Acid

Thomas Jefferson University - Recruiting 18 years or older.
- Phase II, Open Label Study of Intravenous Ascorbic Acid in Combination With Gemcitabine and Erlotinib in the Treatment of Metastatic Pancreatic Cancer.
Ascorbic Acid

Pancreatic Cancer Clinical Trial using TH-302; Nab-paclitaxel; Gemcitabine

EMD Serono - Recruiting 18 years or older.
- An Open-Label, Phase I Dose Escalation Trial of TH-302 in Combination With Gemcitabine and Nab-Paclitaxel in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma.
TH-302; Nab-paclitaxel; Gemcitabine

Locally Advanced Tumor, Metastatic Solid Tissue Tumors, Liver Can Clinical Trial using DCVax-Direct

Northwest Biotherapeutics - Recruiting 18 years to 75 years.
- A PHASE I/II CLINICAL TRIAL EVALUATING DCVax-Direct, AUTOLOGOUS ACTIVATED DENDRITIC CELLS FOR INTRATUMORAL INJECTION, IN PATIENTS WITH SOLID TUMORS.
DCVax-Direct

Metastatic Pancreatic Cancer, or Pancreatic Cancer Clinical Trial using Folfirinox

Yale University - Recruiting 18 years or older.
- Phase II Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer.
Folfirinox

Breast Cancer, Colorectal Cancer, Lung Cancer, Melanoma (Skin), o Clinical Trial

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting N/A or older.
- Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer.

Pancreatic Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Impact on Survival of Cutaneous Reactions in Erlotinib Plus Gemcitabine Treated Patients With Metastatic Pancreatic Cancer Under Conditions of Daily Routine Practice.

Pancreatic Cancer Clinical Trial using LY2495655; Placebo

Eli Lilly and Company - Recruiting 18 years or older.
- A Randomized Phase 2 Placebo-Controlled Study of LY2495655 in Patients With Advanced or Metastatic Pancreatic Cancer Receiving Chemotherapy.
LY2495655; Placebo

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Phase I Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer and Good Performance Status.
6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study: Open-Label Clinical Trial of CPI-613 in Patients With Metastatic Pancreatic Adenocarcinoma and Poor Performance Status.
6,8-bis(benzylthio)octanoic acid

Pancreatic Cancer, or Colorectal Cancer Clinical Trial using Cancer macrobead placement in abdominal cavity

The Rogosin Institute - Recruiting 18 years or older.
- An Open-Label Phase 2 Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Cell-Containing Agarose-Agarose Macrobeads in the Treatment of Patients With Treatment-Resistant, Metastatic Pancreatic or Colorectal Adenocarcinoma.
Cancer macrobead placement in abdominal cavity

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, or S Clinical Trial using wild-type reovirus; carboplatin; paclitaxel

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A 2-arm Randomized Phase II Study of Carboplatin, Paclitaxel Plus Reovirus Serotype-3 Dearing Strain (Reolysinr) vs. Carboplatin and Paclitaxel in the First Line Treatment of Patients With Recurrent or Metastatic Pancreatic Cancer.
wild-type reovirus; carboplatin; paclitaxel

Metastatic Pancreatic Cancer, or Pancreatic Cancer Clinical Trial using IMMU-107; placebo; Gemcitabine

Immunomedics, Inc. - Recruiting 18 years or older.
- An International, Multi-Center, Double-Blind, Randomized, Phase III Trial of 90Y-Clivatuzumab Tetraxetan Plus Low-Dose Gemcitabine Versus Placebo Plus Low-Dose Gemcitabine in Patients With Metastatic (Stage IV) Pancreatic Adenocarcinoma Who Received at Least Two Prior Treatments (PANCRIT-1).
IMMU-107; placebo; Gemcitabine

Metastatic Pancreatic Cancer Clinical Trial using ABI-007; Gemcitabine; simplified LV5FU2

Groupe Cooperateur Multidisciplinaire en Oncologie (GERCOR) - Recruiting 18 years or older.
- Randomized Phase II Study of Weekly ABI-007 Plus Gemcitabine or Simplified LV5FU2 as First-line Therapy in Patients With Metastatic Pancreatic Cancer.
ABI-007; Gemcitabine; simplified LV5FU2

Metastatic Pancreatic Cancer Clinical Trial using mFOLFIRINOX

Sun Yat-sen University - Recruiting 18 years to 65 years.
- Phase ? Trial to Investigate the Efficacy and Safety of mFOLFIRINOX in Patients With Metastatic Pancreatic Cancer in China.
mFOLFIRINOX

Pancreatic Cancer Metastatic Clinical Trial using Dasatinib; mFOLFOX6

University of Florida - Recruiting 18 years or older.
- Phase II Study of 5-Fluorouracil, Oxaliplatin Plus Dasatinib (FOLFOX-D) in First-line Metastatic Pancreatic Adenocarcinoma.
Dasatinib; mFOLFOX6

Metastatic Pancreas Cancer Clinical Trial using 5FU, leucovorin, oxaliplatin; Gemcitabine

AHS Cancer Control Alberta - Recruiting 18 years or older.
- A Multicentre, Randomized, Open Label, Phase III Study of Gemcitabine Versus FOLFOX in the First Line Setting for Metastatic Pancreatic Cancer Patients Using Human Equilibrative Nucleoside Transporter 1 (hENT1) Biomarker Testing..
5FU, leucovorin, oxaliplatin; Gemcitabine

Metastatic Pancreatic Cancer Clinical Trial using TL-118

Tiltan Pharma Ltd. - Recruiting 18 years or older.
- .
TL-118

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Dinaciclib (SCH727965) and MK-2206 in Metastatic Pancreatic Cancer With an Expansion Cohort in Advanced Pancreatic Cancer.
dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

Solid Tumors, Untreated Pancreatic Adenocarcinoma, Pancreatic Can Clinical Trial using PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Plexxikon - Recruiting 18 years or older.
- A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX7486 as a Single Agent and in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced Solid Tumors.
PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Breast Cancer, Pancreatic Cancer, Colorectal Cancer, Non-small-ce Clinical Trial using MORAb-066

Morphotek - Recruiting 18 years or older.
- A Phase I Study of the Safety, Tolerability, and PK of MORAb-066, a Humanized Monoclonal Antibody to Human TF, in Patients With Advanced or Metastatic Breast, Pancreatic, Colorectal, or NSCLC (Adenocarcinoma) Malignancies.
MORAb-066

Metastatic Pancreatic Cancer, or Metastatic Colorectal Cancer Clinical Trial using NPC-1C/NEO-102

Precision Biologics, Inc - Recruiting 18 years to 85 years.
- A Phase 1/2A Therapeutic, Open Label, Multi-Center Clinical Trial of NPC-1C, a Chimeric Monoclonal Antibody, in Adults With Recurrent, Locally Advanced Unresectable or Metastatic Pancreatic and Colorectal Cancer After Standard Therapy.
NPC-1C/NEO-102

Stage IV Pancreatic Cancer Clinical Trial using nab-paclitaxel; Cisplatin; gemcitabine

Pancreatic Cancer Research Team - Recruiting 18 years or older.
- A Phase 1b/2 Pilot Trial of Nab-Paclitaxel Plus Cisplatin Plus Gemcitabine (Nabplagem) in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma (PDA).
nab-paclitaxel; Cisplatin; gemcitabine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Ludwig-Maximilians - University of Munich - Recruiting 18 years to 75 years.
- Phase II Study to Evaluatate the Efficacy of Gemcitabine Plus Erlotinib for RASH-positive Patients With Metastatic Pancreatic Cancer and Friendly Risk Circumstances.
Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Adenocarcinoma of the Pancreas, or Metastatic Disease Clinical Trial using AUY922

University Health Network, Toronto - Recruiting 18 years or older.
- A Phase II Single Arm Study of AUY922 in Patients With Metastatic Pancreatic Adenocarcinoma Who Are Resistant to First Line Chemotherapy.
AUY922

Metastatic Pancreatic Cancer Clinical Trial using Erlotinib

Taipei Veterans General Hospital, Taiwan - Recruiting 18 years or older.
- The Role of Epidermal Growth Factor Receptor (EGFR) and the Downstream Gene KRAS in Pancreatic Cancer Patients Receiving Gemcitabine Combined With Erlotinib Therapy.
Erlotinib

Pancreatic Cancer Clinical Trial using Positron-Emission Tomography (PET) 18F-FLT

AHS Cancer Control Alberta - Recruiting 18 years or older.
- An Imaging Pilot Study of 18F-fluoro-3'-Deoxy-3'-L-fluorothymidine (18F-FLT) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Who Will be Treated With Gemcitabine.
Positron-Emission Tomography (PET) 18F-FLT

Pancreatic Carcinoma Clinical Trial using Gemzar; Revlimid

Karolinska University Hospital - Recruiting 19 years or older.
- Phase I/II Study of Lenalidomide and Gemcitabine as First-line Treatment in Patients With Locally Advanced or Metastatic Pancreatic Cancer.
Gemzar; Revlimid

Pancreas Cancer Clinical Trial using Lapatinib and Capecitabine

Georgetown University - Recruiting 18 years or older.
- Phase II Study of Lapatinib and Capecitabine in 2nd Line Treatment of Locally Advanced/Metastatic Pancreatic Cancer.
Lapatinib and Capecitabine

Locally Advanced Pancreatic Cancer, or Metastatic Pancreatic Canc Clinical Trial using gemcitabine; erlotinib; metformin; placebo

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years to 80 years.
- A Phase II, Randomized, Placebo Controlled Study to Evaluate the Efficacy of the Combination of Gemcitabine, Erlotinib and Metformin in Patients With Locally Advanced and Metastatic Pancreatic Cancer.
gemcitabine; erlotinib; metformin; placebo

Pancreatic Cancer Clinical Trial using efavirenz; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Trial to Assess the Efficacy of Efavirenz as Second-line Monotherapy for the Treatment of Advanced Pancreatic Adenocarcinomas..
efavirenz; quality-of-life assessment

Pancreas Neoplasms Clinical Trial using Docetaxel; Oxaliplatin

University of Ulm - Recruiting 18 years or older.
- Phase II Study: Docetaxel Plus Oxaliplatin as Second-line Therapy in Patients With Advanced Metastatic Pancreatic Cancer.
Docetaxel; Oxaliplatin

Locally Advanced Pancreatic Cancer Clinical Trial using Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino

Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente - Recruiting 18 years to 75 years.
- A Randomized Phase II Study of Gemcitabine/Cisplatin With or Without Sorafenib to Evaluate the Efficacy and Safety in Patients With Locally Advanced or Metastatic Pancreatic Cancer. MAPS Trial.
Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino