Lawson Health Research Institute - Recruiting 2 years to 5 years. - FOR HEALTH: A Family-ORiented Healthy Eating, Activity and Lifestyle Training With Hands-on Experience for Overweight and Obese Preschool Children and Their Families - a Pilot Trial..
Multidisciplinary, family-centered lifestyle intervention with behavioral counseling
Central Hospital, Nancy, France - Recruiting 43 years to 72 years. - Role of the Renin Angiotensin Aldosterone System and Remodeling of the Matrix Cardiac Extra Cellular in the Mechanisms of Transition to Heart Failure in Abdominal Obesity: Prospective Longitudinal Study R2C2 II.
Urine sample; Blood sample; Assessment of sleep apnea syndrome; Electrocardiogram; Glucose tolerance test; Echocardiography; cardiac and abdominal magnetic resonance imaging; Ambulatory blood pressure monitoring; Echotracking; Pulse wave velocity; Composition of body mass by Dual x-ray absorptiometry
MemorialCare Health System - Recruiting 18 years or older. - Comparing Anti-XA Levels in Post-Cesarean Patients With BMI >35 Undergoing Enoxaparin Thromboprophylaxis With Weight Based Dosing Twice Daily Versus Fixed Dose 40 Milligrams Daily.
USGI Medical - Recruiting 22 years to 60 years. - A RANDOMIZED, SUBJECT AND EVALUATOR-BLINDED, PARALLEL-GROUP, MULTICENTER CLINICAL TRIAL USING AN ENDOSCOPIC SUTURING DEVICE (G-CATH EZT SUTURE ANCHOR DELIVERY CATHETER) FOR PRIMARY WEIGHT LOSS.
placement of g-Cath EZ suture anchors; Sham procedure; Diet and Exercise
National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 50 years. - A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple Dose, 2-Period Crossover Study to Evaluate the Effect of RM-493 on Energy Expenditure in Obese Subjects.
University of Illinois at Chicago - Recruiting 4 years to 17 years. - Family Nutrition, Physical Activity (FNPA) Tool: a Motivational Interviewing-based Practice Intervention to Address Pediatric Health Behaviors.
Laboratorios Silanes S.A. de C.V. - Recruiting 8 years to 18 years. - Effect of an Intervention Program With Healthy Habits Plus Metformin or Conjugated Linoleic Acid Over Clinical Parameters and Molecular Pathways of Insulin Resistance in Obese Pediatric Patients.
metformin; Conjugated Linoleic Acid; Placebo; Healthy habits program
University of Zurich - Recruiting 18 years to 75 years. - A Lifestyle Intervention Study Investigating the Role of Interleukin-6 in the Beneficial Effect of Exercise on Beta-cell Function in Obese People and Patients With Type 2 Diabetes.
University of Ulm - Recruiting 14 years to 25 years. - Effectiveness and Safety of Weight Loss Surgery in Adolescents With Extreme Obesity Within a Structured Pre- and Post-surgery Treatment Program, Subproject 3.
National Cancer Institute (NCI) - Recruiting 35 years to 80 years. - A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction Among Patients With a History of Colorectal Adenomas and Elevated Body Mass Index.
rebro County Council - Recruiting 18 years to 60 years. - Obesity Treatment With LCD(Low Calorie Diet) in Primary Health Care - Long Term Effects With or Without Internet Based CBT (Cognitive Behavioral Therapy) , for Weight Stability.
Assistance Publique Hopitaux De Marseille - Recruiting 18 years or older. - Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics.
Aliz Pharma - Recruiting 18 years to 50 years. - A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZP-531 in Healthy Volunteers, Overweight/Obese Volunteers and Patients With Type 2 Diabetes Mellitus.
University of Reading - Recruiting 22 years to 55 years. - Investigating the Effects of Prebiotic-based Snacks on Perceived Feelings of 'Satisfaction' and on the Balance of Bacteria in the Human Gut (NutriSAT).
Copenhagen University Hospital at Herlev - Recruiting 18 years to 42 years. - An Optimized Programming of Healthy Children (APPROACH) - The Most Favourable Dietary Protein:Carbohydrate Ratio During Pregnancy in the Context of New Nordic Diet.
Baptist Health South Florida - Recruiting 18 years or older. - Baptist Employee Healthy Heart Study (BEHHS) - A Novel Web-based Approach to Reduce Cardiovascular Disease Risk in a Diverse Employee Population With Metabolic Syndrome Via Diet and Lifestyle Change.
USGI Medical - Recruiting 20 years to 60 years. - A Randomized Controlled Multicenter Feasibility Study of an IncisionLEss Operating Platform for Primary ObeSiTy vs. Diet-exercise Alone: The MILEPOST Study.
g-CathTM EZ Suture Anchor Delivery Catheter; Diet and Exercise Control Group
Lawson Health Research Institute - Recruiting 18 years to 75 years. - Perineural Ultrasound-Guided Axillary Brachial Plexus Block: Influence of Obesity on Block Performance Time, Failure Rate and Incidence of Acute Complications.
Centre Hospitalier Universitaire Dijon - Recruiting 18 years or older. - Search for Biological Markers of Orosensory Perception of Fatty Acids in Healthy Subjects and Possible Modifications in Patients With Type 2 Diabetes and in Obese Non-diabetic Patients..
Measure the threshold of detection for linoleic acid; Oral stimulation tests; Venous blood samples; Samples for genetic studies (ancillary study)
Universit de Sherbrooke - Recruiting 18 years to 65 years. - Effectiveness and Efficacity of Presurgery Supervised Physical Activity Training on Health of Obese Individuals Waiting for Bariatric Surgery.
New York University School of Medicine - Recruiting 14 years to 17 years. - A Prospective, Open-label Study to Evaluate the Safety and Efficacy of Lap-Bandr Adjustable Gastric Band (LAGBr) Operations in the Treatment of Morbidly Obese Adolescents (Ages 14-17).
Assuta Hospital Systems - Recruiting 14 years to 65 years. - A Prospective Trial for Laparoscopic Adjustable Gastric Banding in Morbidly Obese Patients: Report on Weight Loss, Metabolic Changes and Quality of Life.
University of Rome Tor Vergata - Recruiting 18 years to 75 years. - Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet - A Cross Over Interventional Study.
Hazelnuts; Chocolate; Red wine; Olive Oil; Wild mixed greens; Chestnut; No Dietary Supplement
University of Manitoba - Recruiting 30 years to 75 years. - Lentils as a Functional Food to Improve Glucose Tolerance and Decrease Cardiovascular Disease Risk in Hypercholesterolemic Overweight Individuals.
AGIR Dom - Recruiting 18 years to 80 years. - Comparison of 3 Exercise Training Modalities in Obese Patient With Sleep Apnea Syndrome Treated by Continue Positive Airway Pressure : a Randomized Controlled Study.
InovoBiologic Inc. - Recruiting 18 years to 75 years. - A Randomized, Double Blind, Placebo Controlled Trial Evaluating the Effects of a Highly Viscous Non-starch Polysaccharide (PolyGlycopleXr - PGXr), on Glycemic Control, Cardiometabolic Risk Factors and Weight Loss in Overweight and Obese Type II Diabetics Enrolled in a Medically Supervised Weight Management Program..
University of Modena and Reggio Emilia - Recruiting 18 years to 50 years. - Pregnancy Complications in Women With BMI>25 kg/m2 Enrolled in a Healthy Lifestyle and Eating Habits Program: a Randomized Controlled Trial..
Specific Therapeutic Lifestyle Changes program during pregnancy; Generic dietary and behavioral counselling about lifestyle during pregnancy
University of Chile - Recruiting 25 years to 40 years. - Calorie Restriction Retards the Aging Process by Inducing Sirtuins and Uncoupling Protein 3, Thereby Reducing the Production of Reactive Oxygen Species..
energy restricted mediterranean-type diet; 25 % calorie restriction
University of Turku - Recruiting 18 years or older. - Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota (NAMI): Pre-, Peri- and Postnatal Programming and Origins of Disease: Early Targeting the Epidemics of Allergy and Overweight.
Dietary counselling and placebo; Dietary counselling and probiotics; Placebo capsules; Probiotics; Prebiotics
University Hospital, Lille - Recruiting 18 years to 65 years. - Comparison of Gastric By-Pass and Optimized Medical Treatment in Obese Diabetic Patients in Terms of Mortality, Glycemic Control, and Cost Effectiveness - Prospective, Multicenter, Randomized Study.
CPL Associates - Recruiting 18 years to 95 years. - Comparison Of Endotoxin Concentration And Intestinal Microbiologic Flora Before And After Roux-En-Y Gastric Bypass Or Gastric Banding Surgery In Morbidly Obese Patients With Type 2 Diabetes Mellitus.
University Hospital, Montpellier - Recruiting 18 years to 65 years. - Impact of the Preservation of the Gastric Antrum in the Technique of Sleeve Gastrectomy for the Treatment of the Morbid Obesity: a Prospective,Controlled, Randomized, Multicentrique Study..
Baker IDI Heart and Diabetes Institute - Recruiting 18 years to 30 years. - The Effect of Moxonidine and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension: a Randomised, Double Blind, Active Comparator Clinical Trial.
Helsinki University Central Hospital - Recruiting 20 years to 60 years. - Fructose Consumption Aggravates Dysregulation of Postprandial Lipid Metabolism in Obese Hypertriglyceridemic Men With High Cardiometabolic Risk Profile and Associates With Liver Fat Deposition.
Polish Academy of Sciences - Recruiting 20 years to 50 years. - The Influence of Beta-glucan 1.3D-1.6D, Added to the Low-calorie Diet, on Insulin Sensitivity and the Expression of Selected Proinflammatory Cytokines in Adipose Tissue and Peripheral Blood Mononuclear Cells in Obese Humans.
LG Electronics Inc. - Recruiting 20 years to 70 years. - A Randomized, Open, Parallel, Multi-center Trial to Evaluate Weight Loss Efficacy of Smart Care Service in Obese Patients With Metabolic Syndrome..
King's College Hospital NHS Trust - Recruiting 18 years or older. - The Effect of Weight Loss Surgery on Preservation of Kidney Function and Cardiovascular Disease Risk Factors in Obese Patients With Stages 3-4 Chronic Kidney Disease: a Randomised Controlled Trial.
laparoscopic sleeve gastrectomy; weight management program
Hospices Civils de Lyon - Recruiting 18 years to 60 years. - Validation of the Quark RMR Calorimeter (Cosmed) Versus Deltatrac II (GE Health Care Clinical Systems) for Measuring Energy Expenditure at Rest and in Dynamic Phase After a Meal in Adult Healthy and Obese Volunteers.
University of Surrey - Recruiting 18 years or older. - A 24-Week, National, Single-Centre, Open-Labelled, Randomised, Parallel-Group Trial Comparing Energy Expenditure With Insulin Detemir Versus NPH Insulin Using a Basal-Bolus Regimen With Insulin Aspart as the Mealtime Insulin in Subjects With Type 2 Diabetes.
Glostrup University Hospital, Copenhagen - Recruiting 18 years or older. - Incretin Physiology and Beta-Cell Function Before and After Remission of Type 2 Diabetes - Effects of Long-Term Weight Loss Following Laparoscopic Adjustable Gastric Banding.
Oral glucose tolerance test (OGTT), isoglycemic iv. clamp, liquid meal test, gastric emptying rate
Garvan Institute of Medical Research - Recruiting 18 years to 70 years. - The Role of Adipocyte-Derived Inflammatory Cytokines in the Pathogenesis of Diabetes, Dyslipidaemia, Atherosclerosis and Gastro-Oesophageal Reflux Disease: the Effects of Medical and Surgical Weight Loss.