54 results found.

Osteoarthritis, Knee, or Osteonecrosis Clinical Trial

AO Clinical Investigation and Documentation - Recruiting 40 years or older.
- A Focused Registry on the Conservative Treatment of Osteoarthritis of the Knee.

Osteoarthritis Clinical Trial using Crespine gel; Intragel; Crespine plus gel; Monovisc

October 6 University - Recruiting 20 years to 70 years.
- Intra-articular Hyaluronic Acid Knee Injection: Randomized Control Trial..
Crespine gel; Intragel; Crespine plus gel; Monovisc

Osteoarthritis Clinical Trial using Exercise training; Resistance training with vascular occlusion

University of Sao Paulo - Recruiting 50 years to 65 years.
- Effects of Strength Training Associated With Vascular Occlusion in Patients With Knee Osteoarthritis.
Exercise training; Resistance training with vascular occlusion

Osteoarthritis, Osteoarthritis, Knee, or Osteonecrosis Clinical Trial using Signature Custom Guides; Conventional Instrumentation

Biomet, Inc. - Recruiting 21 years or older.
- A Global Comparison of Signature Guides and Conventional Instrumentation in the Oxford Partial Knee.
Signature Custom Guides; Conventional Instrumentation

Osteoarthritis of the Knee Clinical Trial using Visionaire; Standard surgical technique

Smith & Nephew, Inc. - Recruiting 40 years to 75 years.
- PATIENT-MATCHED INSTRUMENTATION Versus (vs) STANDARD INSTRUMENTATION: A RANDOMIZED CLINICAL TRIAL COMPARING POSTOPERATIVE AXIAL ALIGNMENT and COMPONENT POSITION.
Visionaire; Standard surgical technique

Osteoarthritis of the Knee Clinical Trial using Hydros; Hydros-TA; Triamcinolone Acetonide

Carbylan BioSurgery, Inc. - Recruiting 40 years to 85 years.
- A Multi-center, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Hydros and Hydros-TA Joint Therapies for Management of Pain Associated With Osteoarthritis in the Knee.
Hydros; Hydros-TA; Triamcinolone Acetonide

Knee Osteoarthritis Clinical Trial using Serum and urine samples collections; Imaging (x-rays and MRI)

Artialis - Recruiting 45 years to 80 years.
- Evaluation of the Prognostic Value of Biological Markers, Coll2-1 and Coll2-1NO2 in Patients With Symptomatic Knee Osteoarthritis.
Serum and urine samples collections; Imaging (x-rays and MRI)

Knee Osteoarthritis Clinical Trial using TPX-100 50mg; TPX-100 100mg; TPX-100 200mg; TPX-100 20mg; Placebo

OrthoTrophix, Inc - Recruiting 25 years to 75 years.
- A Randomized, Double-blind, Placebo-controlled, Multi-dose Phase 2 Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees.
TPX-100 50mg; TPX-100 100mg; TPX-100 200mg; TPX-100 20mg; Placebo

Osteoarthritis of the Knee Clinical Trial using X0002; Placebo

Techfields Pharma Co. Ltd - Recruiting 35 years to 85 years.
- A Phase 2, Multicenter, Randomized, Double Blind, Placebo Controlled, Parallel Group, Dose Range Finding Study to Evaluate the Efficacy and Safety of X0002 Spray Versus Placebo in Subjects With Osteoarthritis.
X0002; Placebo

Osteoarthritis Clinical Trial using Tranexamic Acid (TXA); î-Aminocaproic Acid (EACA)

Miller Orthopedic Specialists - Recruiting 18 years to 90 years.
- A Randomized Controlled Trial of Tranexamic Acid and î-Aminocaproic Acid to Reduce Blood Loss Following Total Knee Arthroplasty.
Tranexamic Acid (TXA); î-Aminocaproic Acid (EACA)

Osteoarthritis Knee Clinical Trial using Gel-One; PBS

Seikagaku Corporation - Recruiting 40 years to 80 years.
- A Multi-Center, Randomized, Double-Blind, Phosphate Buffered Saline-Controlled Study to Evaluate Effectiveness and Safety of a Single Intra-Articular Injection of Gel-Oner for the Treatment of Osteoarthritis of the Knee With Open-Label Safety Extension.
Gel-One; PBS

Osteoarthritis of the Knee Clinical Trial using Intensive physiotherapy; Home physiotherapy exercises

University of Edinburgh - Recruiting 16 years or older.
- Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study (TRIO-Physio).
Intensive physiotherapy; Home physiotherapy exercises

Osteoarthritis, or Total Knee Arthroplasty Clinical Trial using CPM; CAM I; CAM II

University of Rostock - Recruiting 50 years to 80 years.
- Effectiveness of New Interventional Approaches to Improve Physical Function Following Total Knee Arthroplasty.
CPM; CAM I; CAM II

Osteoarthritis, Cardiovascular Risk Factors, Cardiovascular Disea Clinical Trial using Cardiovascular risk factors diagnoses collection.; History of cardiovascular disease; Cardiovascular risk factors association

Hospital Parc Taul¡, Sabadell - Recruiting 50 years or older.
- Prevalence of Cardiovascular Risk Factors Between Patients With Knee or Hand Osteoarthritis.
Cardiovascular risk factors diagnoses collection.; History of cardiovascular disease; Cardiovascular risk factors association

Osteoarthritis, Knee Clinical Trial using TKA with Journey II BCS Total Knee System

Smith & Nephew, Inc. - Recruiting N/A or older.
- A Retro-Prospective, Non-randomized, Consecutive Series, SIngle Cohort, Multicenter Adaptive Design Study to Evaluate the Outcomes of Total Knee Arthroplasty (TKA) Using JOURNEYT II BCS TotaL Knee SystEm (The NIMBLE Study).
TKA with Journey II BCS Total Knee System

Bicompartmental Osteoarthritis Clinical Trial using iDuo G2

ConforMIS, Inc. - Recruiting 18 years or older.
- A Prospective, Multicenter Study of the ConforMIS iDuo(R) G2 Bicompartmental Knee Repair System.
iDuo G2

Osteoarthritis Clinical Trial

ConforMIS, Inc. - Recruiting 18 years or older.
- Study Comparing Fit of the iTotal Versus Standard Total Knee Implants.

Leg Length Inequality, Osteoarthritis, Knee, or Osteoarthritis, H Clinical Trial using Shoe lift correction for leg length inequality

University of North Carolina, Chapel Hill - Recruiting 55 years or older.
- Defining and Correcting Limb Length Inequality in Adults With Knee or Hip Symptoms.
Shoe lift correction for leg length inequality

Osteoarthritis Clinical Trial using Wich prosthesis is used

Hvidovre University Hospital - Recruiting 18 years or older.
- Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties. A Randomized Controlled Trial Evaluating Early Component Migration by RSA and Patient Reported Outcome..
Wich prosthesis is used

Knee Osteoarthritis Clinical Trial using Educational and exercise program; Usual care

Assistance Publique - H“pitaux de Paris - Recruiting 50 years to 85 years.
- Evaluation of an Educational Program Associated With Exercises (EDEX) Before Total Knee Arthroplasty.
Educational and exercise program; Usual care

Osteoarthritis Clinical Trial using Complex Ayurvedic Treatment; Conventional Care

Charite University, Berlin, Germany - Recruiting 40 years to 70 years.
- The CARAKA-Trial: Complex Ayurvedic Treatment in Osteoarthritis of the Knee Against Standard Care.A Multicentre, Randomized, Controlled Clinical Trial Based on Traditional Ayurveda-Diagnosis..
Complex Ayurvedic Treatment; Conventional Care

Knee Osteoarthritis Clinical Trial using Euflexxa; Magnetic Resonance Imaging (MRI)

University of California, San Francisco - Recruiting 18 years to 80 years.
- Quantifications of Biochemical Changes of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection Using Novel MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) Techniques.
Euflexxa; Magnetic Resonance Imaging (MRI)

Osteoarthritis of the Knee Clinical Trial using iTotal G2 CR Knee Replacement System

ConforMIS, Inc. - Recruiting 18 years or older.
- A Prospective, Multicenter Study to Evaluate the ConforMIS iTotalr (CR) Knee Replacement System.
iTotal G2 CR Knee Replacement System

Osteoarthritis,, Rheumatoid Arthritis,, Traumatic Arthritis,, or Clinical Trial using Zimmer Persona Total Knee System

Zimmer, Inc. - Recruiting 18 years to 75 years.
- Persona Outcomes Led Assessment Research in Total Knee Arthroplasty.
Zimmer Persona Total Knee System

Knee Osteoarthritis Clinical Trial using Transcutaneous Electrical Nerve Stimulation; Physical Therapy Exercises; No Intervention

Creighton University - Recruiting 19 years to 65 years.
- Corticospinal Excitability and Rehab in Knee Osteoarthritis.
Transcutaneous Electrical Nerve Stimulation; Physical Therapy Exercises; No Intervention

Osteoarthritis of the Knee Clinical Trial using Ampion

Ampio Pharmaceuticals. Inc. - Recruiting 35 years to 85 years.
- A Phase 3 Randomized, Placebo-controlled, Double-blind Study to Evaluate the Safety and Efficacy of a Single Intra-articular Injection of AmpionTM (<5 Kilodalton Ultrafiltrate of 5% Human Serum Albumin) in Adults With Pain Due to Osteoarthritis (OA) of the Knee.
Ampion

Knee Osteoarthritis Clinical Trial using Regenexx SD; Exercise Therapy

Regenerative Sciences, LLC - Recruiting 18 years to 70 years.
- A Randomized Controlled Trial of RegenexxT SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to Total Knee Arthroplasty.
Regenexx SD; Exercise Therapy

Chronic Pain Clinical Trial using Codeine/paracetamol; Oxycodone/naloxone

IRCCS Policlinico S. Matteo - Recruiting 60 years or older.
- A COMPARATIVE STUDY BETWEEN TWO PHARMACOLOGICAL ASSOCIATIONS OXYCODONE/NALOXONE AND CODEINE / PARACETAMOL IN TREATMENT OF MODERATE-SEVERE CHRONIC PAIN DUE TO OSTEOARTHRITIS OF KNEE AND/OR HIP.
Codeine/paracetamol; Oxycodone/naloxone

Knee Osteoarthritis Clinical Trial using arthroplasty

Nantes University Hospital - Recruiting 18 years or older.
- Regenerative Medicine of Articular Cartilage: Characterization and Comparison of Chondrogenic Potential and Immunomodulatory Adult Mesenchymal Stem Cells.
arthroplasty

Knee Osteoarthritis Clinical Trial using Hyaluronic Acid and TH; Hyaluronic Acid; Saline

Anika Therapeutics, Inc. - Recruiting 40 years to 75 years.
- A Randomized, Double-Blind, Placebo Controlled, Multi-Center Study of a Single Injection Cross-Linked Sodium Hyaluronate Combined With Triamcinolone Hexacetonide (Cingal) to Provide Symptomatic Relief of Osteoarthritis of the Knee.
Hyaluronic Acid and TH; Hyaluronic Acid; Saline

Osteoarthritis of the Knee Clinical Trial using Apitox, purified honeybee toxin, lyophilized in saline; histamine

Apimeds, Inc. - Recruiting 30 years to 85 years.
- A Multicenter, Randomized, Double Blind, Active Controlled, Parallel Group, Clinical Study, to Evaluate the Safety and Efficacy of Apitox vs Histamine in Subjects With Refractory Osteoarthritis Pain and Inflammation of the Knee.
Apitox, purified honeybee toxin, lyophilized in saline; histamine

Knee Osteoarthritis Clinical Trial using Synvisc-One Injection; Sham Injection

The Cleveland Clinic - Recruiting 21 years or older.
- Investigating the Efficacy of Synvisc-Oner (Hylan G-F 20) as Adjunctive Therapy for Patients With Knee Osteoarthritis (OA) Requiring Physical Therapy.
Synvisc-One Injection; Sham Injection

Osteoarthritis of the Knee Clinical Trial using Cabbage leave wraps; Diclofenac Gel

Universit„t Duisburg-Essen - Recruiting 18 years or older.
- Randomised Controlled Trial on the Efficacy of Cabbage Leaf Wraps in Symptomatic Primary Osteoarthritis of the Knee.
Cabbage leave wraps; Diclofenac Gel

Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Fe Clinical Trial using NexGen LPS-Flex Mobile Bearing Knee

Zimmer, Inc. - Recruiting N/A or older.
- Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee.
NexGen LPS-Flex Mobile Bearing Knee

Osteoarthritis of the Knee Clinical Trial using Trophic factors from umbilical cord mesenchymal stem cells

Translational Biosciences - Recruiting 18 years to 80 years.
- Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis.
Trophic factors from umbilical cord mesenchymal stem cells

Osteoarthritis, or Degenerative Joint Disease Clinical Trial using Motivational Interviewing (MI); Financial Incentives

Brigham and Women's Hospital - Recruiting 40 years or older.
- .
Motivational Interviewing (MI); Financial Incentives

Knee Osteoarthritis Clinical Trial

University of Milan - Recruiting 40 years to 80 years.
- Prospective Evaluation of Biomarkers Variability in Knee Prosthetic Surgery.

Osteoarthritis, Knee, Arthritis, or Pain Clinical Trial using EMPI Select TENS; Placebo EMPI Select TENS

The Cleveland Clinic - Recruiting 18 years to 85 years.
- Prospective Evaluation of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Relief Following Total Knee Arthroplasty (TKA).
EMPI Select TENS; Placebo EMPI Select TENS

Osteoarthritis Clinical Trial using the prosthesis GMK r without the ancillary MyKnee r LBS; Matched patient cutting blocks MyKnee r LBS

Nantes University Hospital - Recruiting 18 years or older.
- Medico-economic Interest of the Patient Matched Cutting Blocks (Ancillary) MyKnee r LBS During the Poses of Complete Prosthesis of Knee GMK r. Multicentric, Prospective, Controlled, Opened, Randomised Study About a Medical Device..
the prosthesis GMK r without the ancillary MyKnee r LBS; Matched patient cutting blocks MyKnee r LBS

Knee Osteoarthritis Clinical Trial using Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks; Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks; Placebo

Hanlim Pharm. Co., Ltd. - Recruiting 35 years to 75 years.
- For 12 Weeks, the Multi-center, Randomized, Double-blinded, Clinical Study to Evaluate the Efficacy and Safety of Entelon Tab. 150mg Compared With Celebrex Capsule in Patients With Osteoarthritis of Knee (Phase III).
Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks; Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks; Placebo

Unilateral Knee Osteoarthritis Clinical Trial using Exercise in eccentric or concentric mode

University Hospital, Clermont-Ferrand - Recruiting 40 years to 70 years.
- Assessing the Impact of Isokinetic Muscular Strengthening in Eccentric Mode in the Medical Treatment of Knee Osteoarthritis..
Exercise in eccentric or concentric mode

Osteoarthritis, Knee, or Chronic Pain Clinical Trial using tDCS and EAC sham; tDCS sham and EAC sham; tDCS sham and EAC; tDCS and EAC

Hospital de Clinicas de Porto Alegre - Recruiting 18 years or older.
- Effect of Transcranial Direct Current Stimulation and Electro Acupuncture in Pain, Functional Capability and Cortical Excitability in Patients With Osteoarthritis..
tDCS and EAC sham; tDCS sham and EAC sham; tDCS sham and EAC; tDCS and EAC

Osteoarthritis Knee Clinical Trial using Standardized Acupuncture; sham acupuncture; Individualized Acupuncture; Waiting

DongGuk University - Recruiting 20 years to 80 years.
- Clinical Trial to Evaluate and Compare the Efficacy and Safety of Individualized and Standardized Acupuncture for Knee Osteoarthritis Patients: Randomized, Single-blind, Controlled Study.
Standardized Acupuncture; sham acupuncture; Individualized Acupuncture; Waiting

Osteoarthritis, Knee Clinical Trial using Oxford Uni Knee

University of Aarhus - Recruiting 18 years or older.
- Oxford Partial Knee Replacement: A Randomized Clinical Trial of Three Implant Types..
Oxford Uni Knee

Unilateral Primary Osteoarthritis of Knee, or Primary Osteoarthri Clinical Trial using Placebo TENS; Intense TENS (EMPI Select TENS)

University of Iowa - Recruiting 30 years or older.
- Effect of TENS on Hyperalgesia, Pain With Movement, and Function After TKR.
Placebo TENS; Intense TENS (EMPI Select TENS)

Knee Osteoarthritis Clinical Trial using preoperative neuromuscular training; knee OA School

University of Zurich - Recruiting 60 years to 85 years.
- Effect of Pre-surgery Neuromuscular Physiotherapy (PT) on Functional Outcome After Total Knee Replacement (TKR): A Single-blinded Randomized Controlled Trial..
preoperative neuromuscular training; knee OA School

Osteoarthritis Clinical Trial using Hylan GF-20 alone; Triamcinolone

University of Sao Paulo General Hospital - Recruiting 45 years to 80 years.
- Prospective And Randomized Study Evaluating Tthe Effect Of The Association Of Triamcinolone To The Viscosupplementation Of The Knee.
Hylan GF-20 alone; Triamcinolone

Knee Osteoarthritis Clinical Trial using Osteopathic evaluation; Osteopathic evaluation with treatment

Capital District Health Authority, Canada - Recruiting 50 years to 75 years.
- .
Osteopathic evaluation; Osteopathic evaluation with treatment

Osteoarthritis of the Knee Clinical Trial using celecoxib; placebo

University Hospitals of Cleveland - Recruiting 45 years or older.
- A Double-Blind, Placebo-Controlled, Randomized, Crossover Pilot Study of the Efficacy of Celecoxib 200 mg QD in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee..
celecoxib; placebo

Osteoarthritis Clinical Trial using Proactive care and rehabilitation

University of Aarhus - Recruiting N/A or older.
- From Efficacy to Effectiveness of a Proactive Perioperative Care and Rehabilitation in Patients Undergoing Primary Total Hip or Knee Replacement.
Proactive care and rehabilitation

Osteoarthritis Clinical Trial using flex-a-new (food supplement)

Rabin Medical Center - Recruiting 18 years to 85 years.
- .
flex-a-new (food supplement)

Knee Osteoarthritis Clinical Trial using celecoxib

University Hospitals of Cleveland - Recruiting 45 years to 85 years.
- A Double-Blind, Placebo-Controlled, Crossover Pilot Study of the Efficacy of Celecoxib 200 Mg Qd in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee.
celecoxib