46 results found.

Adenocarcinoma, Pancreas, or Neuroendocrine Tumor, Pancreas Clinical Trial using iopromide; CT

Seoul National University Hospital - Recruiting 18 years or older.
- Evaluation of Diagnostic Efficacy of Perfusion CT Using Wide Detector for Staging and Response Prediction After Chemotherapy in Pancreatic Cancer.
iopromide; CT

Pancreatic Cancer Clinical Trial using Gemcitabine; Radiation therapy; pancreaticoduodenectomy

University of Arkansas - Recruiting 18 years or older.
- A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemotherapy With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas.
Gemcitabine; Radiation therapy; pancreaticoduodenectomy

Cancer of the Pancreas Clinical Trial using Pioglitazone

University of Texas Southwestern Medical Center - Recruiting 18 years or older.
- A Phase II Study of Pioglitazone for Patients With Cancer of the Pancreas.
Pioglitazone

Adenocarcinoma of Head of Pancreas, Cholangio Carcinoma, Duodenal Clinical Trial using Open surgery; Laparoscopic surgery

GEM Hospital & Research Center - Recruiting 30 years to 70 years.
- A Prospective Randomized Parallel Group Trial : Laparoscopic Versus Open Pancreatoduodenectomy in Terms of Pathological Radicality & Severity Short Term of Complications According to Expanded Accordion Severity Grading System.
Open surgery; Laparoscopic surgery

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas.
Gemcitabine

Acinar Cell Adenocarcinoma of the Pancreas, Adenocarcinoma of the Clinical Trial using oxaliplatin; irinotecan hydrochloride; leucovorin calcium; fluorouracil; laboratory biomarker analysis

University of Chicago - Recruiting 18 years or older.
- A Genotype-guided Dosing Study of mFOLFIRINOX in Previously Untreated Patients With Advanced Gastrointestinal Malignancies.
oxaliplatin; irinotecan hydrochloride; leucovorin calcium; fluorouracil; laboratory biomarker analysis

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Adenocarcinoma of the Pancreas After Preoperative Chemoradiation Therapy.
Gemcitabine

Hereditary Pancreatitis, or Hereditary Pancreatic Cancer Clinical Trial using MRI

Karolinska University Hospital - Recruiting 18 years or older.
- Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.
MRI

Pancreatic Cancer, Pancreatic Carcinoma Non-resectable, or Locall Clinical Trial using FOLFIRINOX; Algenpantucel-L Immunotherapy; 5-FU Chemoradiation; Gemcitabine; Capecitabine; Nab-Paclitaxel

NewLink Genetics Corporation - Recruiting 18 years or older.
- A Phase III Study of Chemotherapy With or Without Algenpantucel-L (HyperAcuter-Pancreas) Immunotherapy in Subjects With Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer.
FOLFIRINOX; Algenpantucel-L Immunotherapy; 5-FU Chemoradiation; Gemcitabine; Capecitabine; Nab-Paclitaxel

Neoplasms, Pancreas Clinical Trial using cancer stem cell vaccine

Fuda Cancer Hospital, Guangzhou - Recruiting 18 years to 75 years.
- Study of Cancer Stem Cell Vaccine That as a Specific Antigen in Metastatic Adenocarcinoma of the Pancreas.
cancer stem cell vaccine

Hereditary Pancreatic Cancer, Intraductal Papillary Mucinous Neop Clinical Trial using dynamic contrast-enhanced magnetic resonance imaging

OHSU Knight Cancer Institute - Recruiting 18 years to 85 years.
- The Use of Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE MRI) in the Management of Pancreatic Cancer.
dynamic contrast-enhanced magnetic resonance imaging

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Mayo Clinic - Recruiting 18 years or older.
- Phase I Trial of The Combination of Vismodegib and Sirolimus.
vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Colorectal Neoplasms, Gastric Neoplasms, Cholangiocarcinoma, Bile Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- Tumor, Normal Tissue and Specimens From Patients Undergoing Evaluation or Surgical Resection of Solid Tumors.

Pancreatic Cancer Clinical Trial using Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Preoperative Systemic Chemotherapy (Modified FOLFIRINOX) Followed by Radiation Therapy for Patients With High Risk Resectable and Borderline Resectable Adenocarcinoma of the Pancreas.
Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer Clinical Trial using GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Aduro BioTech, Inc. - Recruiting 18 years or older.
- A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma.
GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Liver Cancer, or Pancreatic Cancer Clinical Trial using Intravenous Patient-Controlled Analgesia (IVPCA); Thoracic Epidural Analgesia (TEA); Questionnaires; Pain Assessment

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Randomized Controlled Trial of Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient Controlled Analgesia (3:1) in Patients Undergoing Liver and/or Pancreatic Resection.
Intravenous Patient-Controlled Analgesia (IVPCA); Thoracic Epidural Analgesia (TEA); Questionnaires; Pain Assessment

Colorectal Cancer, or Pancreas Cancer Clinical Trial using Dovitinib

Georgetown University - Recruiting 18 years or older.
- A Pilot Study of Dovitinib as Maintenance and Adjuvant Therapy in Patients With Colorectal and Pancreas Cancers.
Dovitinib

Pancreatic Cancer Clinical Trial using Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Georgetown University - Recruiting 18 years or older.
- A Pilot Study of Molecularly Tailored Therapy for Patients With Metastatic Pancreatic Cancer.
Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Locally Advanced Pancreatic Cancer and Have Started Treatment Wit Clinical Trial using Alecsat

CytoVac A/S - Recruiting 18 years or older.
- A Prospective, Open Phase I Study to Investigate the Tolerability and Efficacy of Administering ALECSAT to Pancreas Cancer Patients.
Alecsat

Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Ca Clinical Trial using ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Northwestern University - Recruiting 18 years or older.
- Ipilimumab and Gemcitabine for Advanced Pancreas Cancer: A Phase Ib Study.
ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Gemcitabine, Dasatinib and Erlotinib in Patients With Advanced Pancreatic Carcinoma.
gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

Pancreas Cancer Clinical Trial using Whipple at the Splenic Artery (WATSA)

Washington University School of Medicine - Recruiting 18 years to 85 years.
- Whipple at the Splenic Artery - A Procedure for Ductal Adenocarcinoma of the Pancreas With Extensive Involvement of the Porto-Mesenteric Axis: A Registry Study.
Whipple at the Splenic Artery (WATSA)

Familial Pancreatic Cancer Clinical Trial using biologic sample preservation procedure; medical chart review; survey administration

Mayo Clinic - Recruiting 18 years or older.
- Biospecimen Resource for Familial Pancreas Research, a Data and Tissue Registry (Also Known as a Bio-repository, Bio-bank, Data and Tissue Database, Data and Tissue Bank, Etc.) to Help Advance Research in Familial Pancreas Disease.
biologic sample preservation procedure; medical chart review; survey administration

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Yale University - Recruiting 18 years or older.
- Phase II Study of Peri-Operative Modified Folfirinox in Localized Pancreatic Cancer.
oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Islet Cell Tumor, Pancreatic Cancer, or Pancreatic Disease Clinical Trial using medical chart review; survey administration; biospecimen collection

Mayo Clinic - Recruiting 18 years or older.
- Biospecimen Resource for Pancreas Research, a Data & Tissue Bank (Also Known as a Bio-repository, Bio-bank, Data & Tissue Database, Data & Tissue Registry, Etc.) to Help Advance Research in Pancreas Disease.
medical chart review; survey administration; biospecimen collection

Cancer of Liver, or Cancer of Pancreas Clinical Trial using Dexmedetomidine

Uppsala University Hospital - Recruiting 18 years to 85 years.
- Effects of Dexmedetomidine on Anaesthesia During IRE Procedures for Solid Tumours.
Dexmedetomidine

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Phase I Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer and Good Performance Status.
6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study: Open-Label Clinical Trial of CPI-613 in Patients With Metastatic Pancreatic Adenocarcinoma and Poor Performance Status.
6,8-bis(benzylthio)octanoic acid

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, or S Clinical Trial using wild-type reovirus; carboplatin; paclitaxel

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A 2-arm Randomized Phase II Study of Carboplatin, Paclitaxel Plus Reovirus Serotype-3 Dearing Strain (Reolysinr) vs. Carboplatin and Paclitaxel in the First Line Treatment of Patients With Recurrent or Metastatic Pancreatic Cancer.
wild-type reovirus; carboplatin; paclitaxel

Patients Must Have Previously Untreated Apparently Resectable Ade Clinical Trial using Paricalcitol

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Randomized Pilot/Pharmacodynamic/Genomic Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer.
Paricalcitol

Early Pancreatic Neoplasia, or Familial Pancreatic Neoplasia Clinical Trial

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study).

Bile Duct Cancer, or Pancreatic Cancer Clinical Trial using Cox2 inhibitor (Celecoxib)

Seoul National University Hospital - Recruiting 19 years to 70 years.
- Prospective, Randomized, Open-label, Controlled Trial of Cyclooxygenase-2 Inhibitor (Celecoxib; Celebrexr) for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer..
Cox2 inhibitor (Celecoxib)

Metastatic Pancreas Cancer Clinical Trial using 5FU, leucovorin, oxaliplatin; Gemcitabine

AHS Cancer Control Alberta - Recruiting 18 years or older.
- A Multicentre, Randomized, Open Label, Phase III Study of Gemcitabine Versus FOLFOX in the First Line Setting for Metastatic Pancreatic Cancer Patients Using Human Equilibrative Nucleoside Transporter 1 (hENT1) Biomarker Testing..
5FU, leucovorin, oxaliplatin; Gemcitabine

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Dinaciclib (SCH727965) and MK-2206 in Metastatic Pancreatic Cancer With an Expansion Cohort in Advanced Pancreatic Cancer.
dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

Pancreatic Cancer Clinical Trial using GVAX pancreatic cancer vaccine; cyclophosphamide

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Randomized Three-arm Neoadjuvant and Adjuvant Feasibility and Toxicity Study of a GM-CSF Secreting Allogeneic Pancreatic Cancer Vaccine Administered Either Alone or in Combination With Either a Single Intravenous Dose or Daily Metronomic Oral Doses of Cyclophosphamide for the Treatment of Patients With Surgically Resected Adenocarcinoma of the Pancreas.
GVAX pancreatic cancer vaccine; cyclophosphamide

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using alisertib; gemcitabine

University of California, Davis - Recruiting 18 years or older.
- Phase I Study of the Combination of MLN8237 and Gemcitabine in Advanced Solid Tumors With Emphasis on Pancreatic Cancer.
alisertib; gemcitabine

Pancreatic Cancer Clinical Trial using protein expression analysis; western blotting; immunohistochemistry staining method; immunologic technique; laboratory biomarker analysis

Fox Chase Cancer Center - Recruiting N/A or older.
- Pharmacodynamic Study of Fibroblast Activity Protein in Patients With Localized Pancreas Cancer Undergoing Surgical Resection.
protein expression analysis; western blotting; immunohistochemistry staining method; immunologic technique; laboratory biomarker analysis

Local Tumor Spread, Advanced Cancer, Metastasized, Pancreatic Can Clinical Trial using Stent; Biliodigestive anastomosis

Universit„tsklinikum Hamburg-Eppendorf - Recruiting 18 years to 90 years.
- Quality of Life After Bilioenteric Anastomosis in Comparison to Endoscopically Placed Stents in Patients With Unresectable Pancreatic Cancer and Jaundice.
Stent; Biliodigestive anastomosis

Pancreatic Cancer Clinical Trial using Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years to 76 years.
- Pilot Study Evaluating An Allogeneic GM-CSF-Transduced Pancreatic Tumor Cell Vaccine (GVAX) and Low Dose Cyclophosphamide Integrated With Fractionated Stereotactic Body Radiation Therapy (SBRT) and FOLFIRINOX Chemotherapy in Patients With Resected Adenocarcinoma of the Pancreas.
Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Adenocarcinoma of the Pancreas, or Metastatic Disease Clinical Trial using AUY922

University Health Network, Toronto - Recruiting 18 years or older.
- A Phase II Single Arm Study of AUY922 in Patients With Metastatic Pancreatic Adenocarcinoma Who Are Resistant to First Line Chemotherapy.
AUY922

Pancreas Cancer Clinical Trial using Lapatinib and Capecitabine

Georgetown University - Recruiting 18 years or older.
- Phase II Study of Lapatinib and Capecitabine in 2nd Line Treatment of Locally Advanced/Metastatic Pancreatic Cancer.
Lapatinib and Capecitabine

Pancreas Cancer Clinical Trial using Secretin Synthetic Human (RG1068)

University Hospital Case Medical Center - Recruiting 18 years or older.
- Evaluation of Efficiency of Secretin-Assisted Computed Tomography Scan and Secretin-Assisted Magnetic Resonance Imaging in Improving Pancreatic Enhancement and Tumor Conspicuity: Prospective Study.
Secretin Synthetic Human (RG1068)

Pancreatic Cancer Clinical Trial using percutaneous fluoro guided celiac plexus neurolysis; EUS guided neurolysis

Asian Institute of Gastroenterology, India - Recruiting 18 years to 75 years.
- A Randomized Trial Comparing Fluoroscopy Guided Percutaneous Technique Versus Endoscopic Ultrasound Guided Technique of Celiac Plexus Neurolysis for Treatment of Pain in Carcinoma Pancreas.
percutaneous fluoro guided celiac plexus neurolysis; EUS guided neurolysis

Pancreas Neoplasms Clinical Trial using Docetaxel; Oxaliplatin

University of Ulm - Recruiting 18 years or older.
- Phase II Study: Docetaxel Plus Oxaliplatin as Second-line Therapy in Patients With Advanced Metastatic Pancreatic Cancer.
Docetaxel; Oxaliplatin

Pancreas Cancer, Bile Duct Cancer, or Ampulla of Vater Cancer Clinical Trial using Enteral Feeding and Total Parental Support

Yonsei University - Recruiting 18 years to 85 years.
- A Prospective, Randomized Trial of Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy.
Enteral Feeding and Total Parental Support

Locally Advanced Pancreatic Cancer Clinical Trial using Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino

Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente - Recruiting 18 years to 75 years.
- A Randomized Phase II Study of Gemcitabine/Cisplatin With or Without Sorafenib to Evaluate the Efficacy and Safety in Patients With Locally Advanced or Metastatic Pancreatic Cancer. MAPS Trial.
Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino