47 results found.

Adenocarcinoma, Pancreas, or Neuroendocrine Tumor, Pancreas Clinical Trial using iopromide; CT

Seoul National University Hospital - Recruiting 18 years or older.
- Evaluation of Diagnostic Efficacy of Perfusion CT Using Wide Detector for Staging and Response Prediction After Chemotherapy in Pancreatic Cancer.
iopromide; CT

Pancreatic Cancer Clinical Trial using Gemcitabine; Radiation therapy; pancreaticoduodenectomy

University of Arkansas - Recruiting 18 years or older.
- A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemotherapy With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas.
Gemcitabine; Radiation therapy; pancreaticoduodenectomy

Adenocarcinoma of Head of Pancreas, Cholangio Carcinoma, Duodenal Clinical Trial using Open surgery; Laparoscopic surgery

GEM Hospital & Research Center - Recruiting 30 years to 70 years.
- A Prospective Randomized Parallel Group Trial : Laparoscopic Versus Open Pancreatoduodenectomy in Terms of Pathological Radicality & Severity Short Term of Complications According to Expanded Accordion Severity Grading System.
Open surgery; Laparoscopic surgery

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas.
Gemcitabine

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Adenocarcinoma of the Pancreas After Preoperative Chemoradiation Therapy.
Gemcitabine

Pancreatic Diseases, Pancreatic Neoplasms, or Pancreatitis Clinical Trial using No interventions, this is an observational study

Aalborg Universityhospital - Recruiting 18 years or older.
- Cell-free DNA Promoter Hypermethylation in Plasma From Patients With Pancreatic Adenocarcinoma, Compared to Patients With Pancreatitis and Pancreatitis and Patients Screened for, But Not Having Pancreatic Adenocarcinoma.'.
No interventions, this is an observational study

Pancreatic Neoplasms Clinical Trial using Oxaliplatin; Irinotecan; Leucovorin; Fluorouracil; laboratory biomarker analysis; flow cytometry; immunohistochemistry staining method; pharmacological study; PF-04136309

Washington University School of Medicine - Recruiting 18 years or older.
- Phase IB Study of FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma.
Oxaliplatin; Irinotecan; Leucovorin; Fluorouracil; laboratory biomarker analysis; flow cytometry; immunohistochemistry staining method; pharmacological study; PF-04136309

Neoplasms, Pancreas Clinical Trial using cancer stem cell vaccine

Fuda Cancer Hospital, Guangzhou - Recruiting 18 years to 75 years.
- Study of Cancer Stem Cell Vaccine That as a Specific Antigen in Metastatic Adenocarcinoma of the Pancreas.
cancer stem cell vaccine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Ipilimumab; Vaccine; FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase 2, Multicenter Study of FOLFIRINOX Followed by Ipilimumab in Combination With Allogeneic GM-CSF Transfected Pancreatic Tumor Vaccine (GVAX) in the Treatment of Metastatic Pancreatic Cancer.
Ipilimumab; Vaccine; FOLFIRINOX

Metastatic Pancreatic Adenocarcinoma Clinical Trial using PEGPH20; Oxaliplatin; Leucovorin; Irinotecan; 5-fluorouracil

Southwest Oncology Group - Recruiting 18 years or older.
- S1313, A Phase IB/II Randomized Study of Modified FOLFIRINOX + Pegylated Recombinant Human Hyaluronidase (PEGPH20) Versus Modified FOLFIRINOX Alone in Patients With Good Performance Status Metastatic Pancreatic Adenocarcinoma.
PEGPH20; Oxaliplatin; Leucovorin; Irinotecan; 5-fluorouracil

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Mayo Clinic - Recruiting 18 years or older.
- Phase I Trial of The Combination of Vismodegib and Sirolimus.
vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Pancreatic Cancer Clinical Trial using Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Preoperative Systemic Chemotherapy (Modified FOLFIRINOX) Followed by Radiation Therapy for Patients With High Risk Resectable and Borderline Resectable Adenocarcinoma of the Pancreas.
Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer Clinical Trial using GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Aduro BioTech, Inc. - Recruiting 18 years or older.
- A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma.
GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Adenocarcinoma, or Pancreatic Neoplasms Clinical Trial using X-82; Everolimus

Washington University School of Medicine - Recruiting 18 years or older.
- A Phase I/II Study of X-82, an Oral Anti-VEGFR Tyrosine Kinase Inhibitor, With Everolimus for Patients With Pancreatic Neuroendocrine Tumors.
X-82; Everolimus

Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Ca Clinical Trial using ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Northwestern University - Recruiting 18 years or older.
- Ipilimumab and Gemcitabine for Advanced Pancreas Cancer: A Phase Ib Study.
ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Gemcitabine, Dasatinib and Erlotinib in Patients With Advanced Pancreatic Carcinoma.
gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

Melanoma, Breast Neoplasms, Lobular Carcinoma, Triple-negative Br Clinical Trial using LGK974

Novartis - Recruiting 18 years or older.
- A Phase I, Open-label, Dose Escalation Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands.
LGK974

Left-sided Pancreatic Cancer, or Ductal Adenocarcinoma Clinical Trial using Radical Antegrade Modular Pancreatectomy with Splenectomy; Radical Antegrade Modular Pancreatectomy without splenectomy

Yonsei University - Recruiting 20 years to 80 years.
- .
Radical Antegrade Modular Pancreatectomy with Splenectomy; Radical Antegrade Modular Pancreatectomy without splenectomy

KRAS Mutated Colorectal Adenocarcinoma, Metastatic Pancreatic Ade Clinical Trial using MEK162 + AMG 479

Novartis - Recruiting 18 years or older.
- A Phase Ib/II Open-label, Multi-center Study of the Combination of MEK162 Plus AMG 479 (Ganitumab) in Adult Patients With Selected Advanced Solid Tumors.
MEK162 + AMG 479

Pancreatic Cancer Clinical Trial using TH-302; Nab-paclitaxel; Gemcitabine

EMD Serono - Recruiting 18 years or older.
- An Open-Label, Phase I Dose Escalation Trial of TH-302 in Combination With Gemcitabine and Nab-Paclitaxel in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma.
TH-302; Nab-paclitaxel; Gemcitabine

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Yale University - Recruiting 18 years or older.
- Phase II Study of Peri-Operative Modified Folfirinox in Localized Pancreatic Cancer.
oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Pancreatic Adenocarcinoma Clinical Trial

Centre Hospitalier Departemental Vendee - Recruiting 18 years or older.
- PAncreatic Adenocarcinoma in Hospital.

Pancreatic Adenocarcinoma Clinical Trial using NovoTTF-100L; Gemcitabine

NovoCure Ltd. - Recruiting 18 years or older.
- An Open Label Pilot Study of NovoTTF-100L Concomitant With Gemcitabine for Front-line Therapy of Advanced Pancreatic Adenocarcinoma.
NovoTTF-100L; Gemcitabine

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Phase I Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer and Good Performance Status.
6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study: Open-Label Clinical Trial of CPI-613 in Patients With Metastatic Pancreatic Adenocarcinoma and Poor Performance Status.
6,8-bis(benzylthio)octanoic acid

Pancreatic Cancer, or Colorectal Cancer Clinical Trial using Cancer macrobead placement in abdominal cavity

The Rogosin Institute - Recruiting 18 years or older.
- An Open-Label Phase 2 Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Cell-Containing Agarose-Agarose Macrobeads in the Treatment of Patients With Treatment-Resistant, Metastatic Pancreatic or Colorectal Adenocarcinoma.
Cancer macrobead placement in abdominal cavity

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, or S Clinical Trial using wild-type reovirus; carboplatin; paclitaxel

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A 2-arm Randomized Phase II Study of Carboplatin, Paclitaxel Plus Reovirus Serotype-3 Dearing Strain (Reolysinr) vs. Carboplatin and Paclitaxel in the First Line Treatment of Patients With Recurrent or Metastatic Pancreatic Cancer.
wild-type reovirus; carboplatin; paclitaxel

Metastatic Pancreatic Cancer, or Pancreatic Cancer Clinical Trial using IMMU-107; placebo; Gemcitabine

Immunomedics, Inc. - Recruiting 18 years or older.
- An International, Multi-Center, Double-Blind, Randomized, Phase III Trial of 90Y-Clivatuzumab Tetraxetan Plus Low-Dose Gemcitabine Versus Placebo Plus Low-Dose Gemcitabine in Patients With Metastatic (Stage IV) Pancreatic Adenocarcinoma Who Received at Least Two Prior Treatments (PANCRIT-1).
IMMU-107; placebo; Gemcitabine

Patients Must Have Previously Untreated Apparently Resectable Ade Clinical Trial using Paricalcitol

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Randomized Pilot/Pharmacodynamic/Genomic Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer.
Paricalcitol

Stage IA Pancreatic Adenocarcinoma, Stage IB Pancreatic Adenocarc Clinical Trial using nab-paclitaxel; gemcitabine

Fudan University - Recruiting 18 years to 75 years.
- A Phase II, Single-arm Study to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients With Pancreatic Cancer After Curative Resection.
nab-paclitaxel; gemcitabine

Pancreatic Cancer Metastatic Clinical Trial using Dasatinib; mFOLFOX6

University of Florida - Recruiting 18 years or older.
- Phase II Study of 5-Fluorouracil, Oxaliplatin Plus Dasatinib (FOLFOX-D) in First-line Metastatic Pancreatic Adenocarcinoma.
Dasatinib; mFOLFOX6

Pancreatic Ductal Adenocarcinoma Clinical Trial using The risk assessment questionnaire; Blood specimens; tumor tissue samples will be requested

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma.
The risk assessment questionnaire; Blood specimens; tumor tissue samples will be requested

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Dinaciclib (SCH727965) and MK-2206 in Metastatic Pancreatic Cancer With an Expansion Cohort in Advanced Pancreatic Cancer.
dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

Pancreatic Cancer Clinical Trial using GVAX pancreatic cancer vaccine; cyclophosphamide

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Randomized Three-arm Neoadjuvant and Adjuvant Feasibility and Toxicity Study of a GM-CSF Secreting Allogeneic Pancreatic Cancer Vaccine Administered Either Alone or in Combination With Either a Single Intravenous Dose or Daily Metronomic Oral Doses of Cyclophosphamide for the Treatment of Patients With Surgically Resected Adenocarcinoma of the Pancreas.
GVAX pancreatic cancer vaccine; cyclophosphamide

Solid Tumors, Untreated Pancreatic Adenocarcinoma, Pancreatic Can Clinical Trial using PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Plexxikon - Recruiting 18 years or older.
- A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX7486 as a Single Agent and in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced Solid Tumors.
PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Breast Cancer, Pancreatic Cancer, Colorectal Cancer, Non-small-ce Clinical Trial using MORAb-066

Morphotek - Recruiting 18 years or older.
- A Phase I Study of the Safety, Tolerability, and PK of MORAb-066, a Humanized Monoclonal Antibody to Human TF, in Patients With Advanced or Metastatic Breast, Pancreatic, Colorectal, or NSCLC (Adenocarcinoma) Malignancies.
MORAb-066

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using alisertib; gemcitabine

University of California, Davis - Recruiting 18 years or older.
- Phase I Study of the Combination of MLN8237 and Gemcitabine in Advanced Solid Tumors With Emphasis on Pancreatic Cancer.
alisertib; gemcitabine

Pancreatic Adenocarcinoma, or Colorectal Cancer Clinical Trial

Oslo University Hospital - Recruiting N/A or older.
- The Process of Metastasis in Colorectal Cancer Tumour Biology and Prognostic Factors in Pancreatic Cancer.

Stage IV Pancreatic Cancer Clinical Trial using nab-paclitaxel; Cisplatin; gemcitabine

Pancreatic Cancer Research Team - Recruiting 18 years or older.
- A Phase 1b/2 Pilot Trial of Nab-Paclitaxel Plus Cisplatin Plus Gemcitabine (Nabplagem) in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma (PDA).
nab-paclitaxel; Cisplatin; gemcitabine

Pancreatic Cancer Clinical Trial using Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years to 76 years.
- Pilot Study Evaluating An Allogeneic GM-CSF-Transduced Pancreatic Tumor Cell Vaccine (GVAX) and Low Dose Cyclophosphamide Integrated With Fractionated Stereotactic Body Radiation Therapy (SBRT) and FOLFIRINOX Chemotherapy in Patients With Resected Adenocarcinoma of the Pancreas.
Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Pancreatic Adenocarcinoma Clinical Trial using Gemcitabine

University of Tehran - Recruiting 18 years to 80 years.
- EUS-guided Intratumoral Gemcitabine Therapy in Locally Advanced Unresectable Pancreatic Cancer: A Phase 1 Study.
Gemcitabine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Ludwig-Maximilians - University of Munich - Recruiting 18 years to 75 years.
- Phase II Study to Evaluatate the Efficacy of Gemcitabine Plus Erlotinib for RASH-positive Patients With Metastatic Pancreatic Cancer and Friendly Risk Circumstances.
Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Pancreatic Cancer Stage II, or Pancreatic Cancer Stage III Clinical Trial using Neoadjuvant gemcitabine, capecitabine, and docetaxel; Gemcitabine, capecitabine, docetaxel followed by radiotherapy

Columbia University - Recruiting 18 years or older.
- Phase II Study: Neoadjuvant Gemcitabine, Docetaxel and Capecitabine Followed by Neoadjuvant Radiation Therapy With Gemcitabine and Capecitabine in the Treatment of Stage II and III Pancreatic Adenocarcinoma.
Neoadjuvant gemcitabine, capecitabine, and docetaxel; Gemcitabine, capecitabine, docetaxel followed by radiotherapy

Pancreatic Cancer Clinical Trial using capecitabine; cisplatin; epirubicin; gemcitabine

IRCCS San Raffaele - Recruiting 18 years to 75 years.
- Randomized Phase II-III Trial of Peri- or Post-Operative Chemotherapy in Resectable Pancreatic Adenocarcinoma.
capecitabine; cisplatin; epirubicin; gemcitabine

Pancreatic Adenocarcinoma Clinical Trial using 5 Fluorouracil; Leucovorin; Irinotecan; Oxaliplatin

NorthShore University HealthSystem - Recruiting 18 years or older.
- A Pilot Study of Neoadjuvant and Adjuvant mFOLFIRINOX in Localized, Resectable Pancreatic Adenocarcinoma.
5 Fluorouracil; Leucovorin; Irinotecan; Oxaliplatin

Adenocarcinoma of the Pancreas, or Metastatic Disease Clinical Trial using AUY922

University Health Network, Toronto - Recruiting 18 years or older.
- A Phase II Single Arm Study of AUY922 in Patients With Metastatic Pancreatic Adenocarcinoma Who Are Resistant to First Line Chemotherapy.
AUY922