114 results found.

Adenocarcinoma, Pancreas, or Neuroendocrine Tumor, Pancreas Clinical Trial using iopromide; CT

Seoul National University Hospital - Recruiting 18 years or older.
- Evaluation of Diagnostic Efficacy of Perfusion CT Using Wide Detector for Staging and Response Prediction After Chemotherapy in Pancreatic Cancer.
iopromide; CT

Metastatic Colorectal Cancer, Metastatic Gastric Cancer, Metastat Clinical Trial using CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 66 years.
- A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract Cancers.
CD8+ young TIL; Aldesleukin; Cyclophosphamide; Fludarabine

Pancreatic Cancer Clinical Trial using Gemcitabine; Radiation therapy; pancreaticoduodenectomy

University of Arkansas - Recruiting 18 years or older.
- A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemotherapy With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas.
Gemcitabine; Radiation therapy; pancreaticoduodenectomy

Adenocarcinoma of Head of Pancreas, Cholangio Carcinoma, Duodenal Clinical Trial using Open surgery; Laparoscopic surgery

GEM Hospital & Research Center - Recruiting 30 years to 70 years.
- A Prospective Randomized Parallel Group Trial : Laparoscopic Versus Open Pancreatoduodenectomy in Terms of Pathological Radicality & Severity Short Term of Complications According to Expanded Accordion Severity Grading System.
Open surgery; Laparoscopic surgery

Ovarian Cancer, Pancreatic Cancer Clinical Trial using DMUC5754A

Genentech - Recruiting 18 years or older.
- A Phase I, Open-Label, Dose Escalation Study of the Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer.
DMUC5754A

Ovarian Cancer, Pancreatic Cancer Clinical Trial using DMOT4039A

Genentech - Recruiting 18 years or older.
- A Phase I, Open Label Study of the Safety and Pharmacokinetics of Escalating Doses of DMOT4039A in Patients With Unresectable Pancreatic or Platinum Resistant Ovarian Cancer.
DMOT4039A

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas.
Gemcitabine

Pancreatic Cancer Clinical Trial using Gemcitabine

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Adenocarcinoma of the Pancreas After Preoperative Chemoradiation Therapy.
Gemcitabine

Pancreatic Diseases, Pancreatic Neoplasms, or Pancreatitis Clinical Trial using No interventions, this is an observational study

Aalborg Universityhospital - Recruiting 18 years or older.
- Cell-free DNA Promoter Hypermethylation in Plasma From Patients With Pancreatic Adenocarcinoma, Compared to Patients With Pancreatitis and Pancreatitis and Patients Screened for, But Not Having Pancreatic Adenocarcinoma.'.
No interventions, this is an observational study

Hereditary Pancreatitis, or Hereditary Pancreatic Cancer Clinical Trial using MRI

Karolinska University Hospital - Recruiting 18 years or older.
- Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.
MRI

Pancreatic Cancer, Pancreatic Carcinoma Non-resectable, or Locall Clinical Trial using FOLFIRINOX; Algenpantucel-L Immunotherapy; 5-FU Chemoradiation; Gemcitabine; Capecitabine; Nab-Paclitaxel

NewLink Genetics Corporation - Recruiting 18 years or older.
- A Phase III Study of Chemotherapy With or Without Algenpantucel-L (HyperAcuter-Pancreas) Immunotherapy in Subjects With Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer.
FOLFIRINOX; Algenpantucel-L Immunotherapy; 5-FU Chemoradiation; Gemcitabine; Capecitabine; Nab-Paclitaxel

Neoplasms, Pancreas Clinical Trial using cancer stem cell vaccine

Fuda Cancer Hospital, Guangzhou - Recruiting 18 years to 75 years.
- Study of Cancer Stem Cell Vaccine That as a Specific Antigen in Metastatic Adenocarcinoma of the Pancreas.
cancer stem cell vaccine

Cancer Metastatic to the Liver, Hepatocellular Carcinoma That is Clinical Trial using PV-10 (10% rose bengal disodium)

Provectus Pharmaceuticals - Recruiting 18 years or older.
- A Phase 1 Study to Assess the Safety, Tolerability and Pharmacokinetics of PV-10 Chemoablation of Cancer Metastatic to the Liver or Hepatocellular Carcinoma Not Amenable to Resection or Transplant.
PV-10 (10% rose bengal disodium)

Pancreatic Cancer Clinical Trial using 24 Gy in 3 fractions

UMC Utrecht - Recruiting 18 years or older.
- Cone-beam CT Guided Stereotactic Radiation Therapy for Locally Advanced Pancreatic Cancer.
24 Gy in 3 fractions

Esophageal Cancer, Bile Duct Neoplasms, Gastric Cancer, Liver Can Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Collection of Tissue, Blood and Other Specimens From Patients With Benign and Malignant Tumors of the Soft Tissue, Gastrointestinal Tract, and Other Intra-abdominal Sites..

Hereditary Pancreatic Cancer, Intraductal Papillary Mucinous Neop Clinical Trial using dynamic contrast-enhanced magnetic resonance imaging

OHSU Knight Cancer Institute - Recruiting 18 years to 85 years.
- The Use of Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE MRI) in the Management of Pancreatic Cancer.
dynamic contrast-enhanced magnetic resonance imaging

Pancreatic Cancer Patients Diagnosed With Locally Advanced or Met Clinical Trial using L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine

Philogen S.p.A. - Recruiting 18 years to 70 years.
- Phase I Study of the Tumor-targeting Human L19IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Gemcitabine in Patients With Advanced Pancreatic Cancer.
L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Ipilimumab; Vaccine; FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase 2, Multicenter Study of FOLFIRINOX Followed by Ipilimumab in Combination With Allogeneic GM-CSF Transfected Pancreatic Tumor Vaccine (GVAX) in the Treatment of Metastatic Pancreatic Cancer.
Ipilimumab; Vaccine; FOLFIRINOX

Histologically or Cytologically Confirmed Pancreatic Ca, or Unres Clinical Trial using Gemcitabine; Intra Arterial Catheterization and Embolization; Indwelling Intraarterial Catheter

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Regional Chemotherapy in Locally Advanced Pancreatic Cancer: RECLAP Trial.
Gemcitabine; Intra Arterial Catheterization and Embolization; Indwelling Intraarterial Catheter

Lung or Prostatic Neoplasms, Colorectal or Kidney Neoplasms, Panc Clinical Trial using NK cells +CliniMACs CD3 and CD56 systems

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity With Bortezomib.
NK cells +CliniMACs CD3 and CD56 systems

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Mayo Clinic - Recruiting 18 years or older.
- Phase I Trial of The Combination of Vismodegib and Sirolimus.
vismodegib; sirolimus; positron emission tomography; computed tomography; pharmacological study; laboratory biomarker analysis; fludeoxyglucose F 18

Metastatic Cancer, Pancreatic Cancer, Mesothelioma, Ovarian Cance Clinical Trial using Fludarabine; Cycolphosphamide; Aldesleukin

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-mesothelin Gene Engineered Lymphocytes.
Fludarabine; Cycolphosphamide; Aldesleukin

Pancreatic Cancer Clinical Trial using Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Preoperative Systemic Chemotherapy (Modified FOLFIRINOX) Followed by Radiation Therapy for Patients With High Risk Resectable and Borderline Resectable Adenocarcinoma of the Pancreas.
Oxaliplatin; Irinotecan; 5-FU; Gemcitabine; Radiation Therapy

Pancreatic Carcinoma Non-resectable Clinical Trial using CyberKnifer Stereotactic Body Radiotherapy(SBRT)Boost

Ottawa Hospital Research Institute - Recruiting 19 years to 80 years.
- Phase I Time-to-Event Continual Reassessment (TITE-CRM) Dose Escalation Trial of CyberKnifer Stereotactic Body Radiotherapy (SBRT) Boost With Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Pancreatic Cancer.
CyberKnifer Stereotactic Body Radiotherapy(SBRT)Boost

2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer Clinical Trial using GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Aduro BioTech, Inc. - Recruiting 18 years or older.
- A Phase 2B, Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (With Cyclophosphamide) and CRS 207 Compared to Chemotherapy or to CRS-207 Alone in Adults With Previously-Treated Metastatic Pancreatic Adenocarcinoma.
GVAX Pancreas Vaccine; CRS-207; gemcitabine, capecitabine, 5-FU, irinotecan or erlotinib; cyclophosphamide

Liver Cancer, or Pancreatic Cancer Clinical Trial using Intravenous Patient-Controlled Analgesia (IVPCA); Thoracic Epidural Analgesia (TEA); Questionnaires; Pain Assessment

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Randomized Controlled Trial of Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient Controlled Analgesia (3:1) in Patients Undergoing Liver and/or Pancreatic Resection.
Intravenous Patient-Controlled Analgesia (IVPCA); Thoracic Epidural Analgesia (TEA); Questionnaires; Pain Assessment

Fallopian Tube, Primary Peritoneal Cancer, or Solid Tumors (eg Br Clinical Trial using ABT-767

AbbVie - Recruiting 18 years or older.
- A Phase 1 Study of ABT-767 in BRCA1 or BRCA2 Mutation Carriers With Advanced Solid Tumors and in Subjects With High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer.
ABT-767

Stage IV Pancreatic Cancer Clinical Trial using Gemcitabine; nab-paclitaxel; FOLFIRINOX; Immunohistochemistry (IHC) Analysis; Metformin

Pancreatic Cancer Research Team - Recruiting 18 years or older.
- A Phase II Study of Induction Consolidation and Maintenance Approach for Patients With Advanced Pancreatic Cancer.
Gemcitabine; nab-paclitaxel; FOLFIRINOX; Immunohistochemistry (IHC) Analysis; Metformin

Metastatic Pancreatic Cancer Clinical Trial using Veliparib and 5-FU and Oxaliplatin and Leucovorin

Georgetown University - Recruiting 18 years or older.
- A Phase I/II Study of ABT-888 in Combination With 5-fluorouracil and Oxaliplatin (Modified FOLFOX-6) in Patients With Metastatic Pancreatic Cancer.
Veliparib and 5-FU and Oxaliplatin and Leucovorin

Pancreatic Cancer Clinical Trial using Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Georgetown University - Recruiting 18 years or older.
- A Pilot Study of Molecularly Tailored Therapy for Patients With Metastatic Pancreatic Cancer.
Gem-OX; Gem-5FU; Gem-Tax; Modified FOLFOX-6; Ox-Tax; FOLFIRI; Tax-Iri

Locally Advanced Pancreatic Cancer and Have Started Treatment Wit Clinical Trial using Alecsat

CytoVac A/S - Recruiting 18 years or older.
- A Prospective, Open Phase I Study to Investigate the Tolerability and Efficacy of Administering ALECSAT to Pancreas Cancer Patients.
Alecsat

Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Ca Clinical Trial using ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Northwestern University - Recruiting 18 years or older.
- Ipilimumab and Gemcitabine for Advanced Pancreas Cancer: A Phase Ib Study.
ipilimumab; gemcitabine hydrochloride; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Gemcitabine, Dasatinib and Erlotinib in Patients With Advanced Pancreatic Carcinoma.
gemcitabine hydrochloride; dasatinib; erlotinib hydrochloride

Stage IV Pancreatic Cancer Clinical Trial using OMP-59R5; Gemcitabine; Placebo; Nab-Paclitaxel

OncoMed Pharmaceuticals, Inc. - Recruiting 18 years to 90 years.
- A Phase 1b/2 Study of OMP-59R5 in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer.
OMP-59R5; Gemcitabine; Placebo; Nab-Paclitaxel

Melanoma, Breast Neoplasms, Lobular Carcinoma, Triple-negative Br Clinical Trial using LGK974

Novartis - Recruiting 18 years or older.
- A Phase I, Open-label, Dose Escalation Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands.
LGK974

Stage IV Pancreatic Cancer Clinical Trial using VXM01; Placebo

Vaximm GmbH - Recruiting 18 years or older.
- VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic Cancer to Examine Safety, Tolerability, and Immune Response to the Investigational VEGFR-2 DNA Vaccine VXM01.
VXM01; Placebo

Stage IV Pancreatic Cancer Clinical Trial using Ascorbic Acid

Thomas Jefferson University - Recruiting 18 years or older.
- Phase II, Open Label Study of Intravenous Ascorbic Acid in Combination With Gemcitabine and Erlotinib in the Treatment of Metastatic Pancreatic Cancer.
Ascorbic Acid

Left-sided Pancreatic Cancer, or Ductal Adenocarcinoma Clinical Trial using Radical Antegrade Modular Pancreatectomy with Splenectomy; Radical Antegrade Modular Pancreatectomy without splenectomy

Yonsei University - Recruiting 20 years to 80 years.
- .
Radical Antegrade Modular Pancreatectomy with Splenectomy; Radical Antegrade Modular Pancreatectomy without splenectomy

Pancreatic Cancer, or Stage IV Pancreatic Cancer Clinical Trial using OMP-54F28, Nab-Paclitaxel and Gemcitabine

OncoMed Pharmaceuticals, Inc. - Recruiting 18 years to 90 years.
- A Phase 1b Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer.
OMP-54F28, Nab-Paclitaxel and Gemcitabine

Pancreatic Cancer Clinical Trial using Minocycline; Placebo; Questionnaires

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Randomized, Placebo Controlled-Double Blind Study of Minocycline for Reducing the Symptom Burden for Pancreatic Cancer Patients.
Minocycline; Placebo; Questionnaires

Pancreatic Cancer Clinical Trial using TH-302; Nab-paclitaxel; Gemcitabine

EMD Serono - Recruiting 18 years or older.
- An Open-Label, Phase I Dose Escalation Trial of TH-302 in Combination With Gemcitabine and Nab-Paclitaxel in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma.
TH-302; Nab-paclitaxel; Gemcitabine

Familial Pancreatic Cancer Clinical Trial using biologic sample preservation procedure; medical chart review; survey administration

Mayo Clinic - Recruiting 18 years or older.
- Biospecimen Resource for Familial Pancreas Research, a Data and Tissue Registry (Also Known as a Bio-repository, Bio-bank, Data and Tissue Database, Data and Tissue Bank, Etc.) to Help Advance Research in Familial Pancreas Disease.
biologic sample preservation procedure; medical chart review; survey administration

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Yale University - Recruiting 18 years or older.
- Phase II Study of Peri-Operative Modified Folfirinox in Localized Pancreatic Cancer.
oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; therapeutic conventional surgery; laboratory biomarker analysis

Locally Advanced Tumor, Metastatic Solid Tissue Tumors, Liver Can Clinical Trial using DCVax-Direct

Northwest Biotherapeutics - Recruiting 18 years to 75 years.
- A PHASE I/II CLINICAL TRIAL EVALUATING DCVax-Direct, AUTOLOGOUS ACTIVATED DENDRITIC CELLS FOR INTRATUMORAL INJECTION, IN PATIENTS WITH SOLID TUMORS.
DCVax-Direct

Islet Cell Tumor, Pancreatic Cancer, or Pancreatic Disease Clinical Trial using medical chart review; survey administration; biospecimen collection

Mayo Clinic - Recruiting 18 years or older.
- Biospecimen Resource for Pancreas Research, a Data & Tissue Bank (Also Known as a Bio-repository, Bio-bank, Data & Tissue Database, Data & Tissue Registry, Etc.) to Help Advance Research in Pancreas Disease.
medical chart review; survey administration; biospecimen collection

Metastatic Pancreatic Cancer, or Pancreatic Cancer Clinical Trial using Folfirinox

Yale University - Recruiting 18 years or older.
- Phase II Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer.
Folfirinox

Gastric Cancer, or Pancreatic Cancer Clinical Trial using questionnaire, Blood specimens

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Gastroenteropancreatic and Unknown Primary Neuroendocrine Registry A Collection of Clinical and Epidemiologic Data Combined With Tissue and Blood From Patients With a Diagnosis of Neuroendocrine Tumors.
questionnaire, Blood specimens

Pancreatic Cancer Clinical Trial using Gemcitabine (Gemzar), docetaxel (Taxotere), and capecitabine (Xeloda)

Columbia University - Recruiting 18 years to 75 years.
- A Phase II Study of Gemzar, Taxotere, and Xeloda (GTX) for Adjuvant Pancreatic Cancer.
Gemcitabine (Gemzar), docetaxel (Taxotere), and capecitabine (Xeloda)

Breast Cancer, Colorectal Cancer, Lung Cancer, Melanoma (Skin), o Clinical Trial

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting N/A or older.
- Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer.

Pancreatic Neoplasms Clinical Trial using Ascorbate; Gemcitabine; Radiation therapy

University of Iowa - Recruiting 18 years or older.
- Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I.
Ascorbate; Gemcitabine; Radiation therapy

Pancreatic Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- Impact on Survival of Cutaneous Reactions in Erlotinib Plus Gemcitabine Treated Patients With Metastatic Pancreatic Cancer Under Conditions of Daily Routine Practice.

Pancreatic Cancer Clinical Trial using LY2495655; Placebo

Eli Lilly and Company - Recruiting 18 years or older.
- A Randomized Phase 2 Placebo-Controlled Study of LY2495655 in Patients With Advanced or Metastatic Pancreatic Cancer Receiving Chemotherapy.
LY2495655; Placebo

Pancreatic Cancer Clinical Trial using Kanglaite Injection plus gemcitabine; Gemcitabine

KangLaiTe USA - Recruiting 18 years or older.
- A Randomized Dose Escalation, Safety and Exploratory Efficacy Study of Kanglaite Injection Plus Gemcitabine (G+K) Versus Gemcitabine in Patients With Advanced Pancreatic Cancer.
Kanglaite Injection plus gemcitabine; Gemcitabine

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Phase I Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Modified FOLFIRINOX in Patients With Metastatic Pancreatic Cancer and Good Performance Status.
6,8-bis(benzylthio)octanoic acid; oxaliplatin; leucovorin calcium; irinotecan hydrochloride; fluorouracil; laboratory biomarker analysis

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using 6,8-bis(benzylthio)octanoic acid

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study: Open-Label Clinical Trial of CPI-613 in Patients With Metastatic Pancreatic Adenocarcinoma and Poor Performance Status.
6,8-bis(benzylthio)octanoic acid

Pancreatic Cancer, or Colorectal Cancer Clinical Trial using Cancer macrobead placement in abdominal cavity

The Rogosin Institute - Recruiting 18 years or older.
- An Open-Label Phase 2 Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Cell-Containing Agarose-Agarose Macrobeads in the Treatment of Patients With Treatment-Resistant, Metastatic Pancreatic or Colorectal Adenocarcinoma.
Cancer macrobead placement in abdominal cavity

Colorectal Cancer Clinical Trial using Dacomitinib; PD-0325901; Irinotecan; Docetaxel; Capecitabine

The Netherlands Cancer Institute - Recruiting 18 years or older.
- Phase I/II Study With the Combination of Dacomitinib and PD-0325901 in Advanced KRAS Mutation Positive Colorectal, Non-small Cell Lung and Pancreatic Cancer.
Dacomitinib; PD-0325901; Irinotecan; Docetaxel; Capecitabine

Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, or S Clinical Trial using wild-type reovirus; carboplatin; paclitaxel

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A 2-arm Randomized Phase II Study of Carboplatin, Paclitaxel Plus Reovirus Serotype-3 Dearing Strain (Reolysinr) vs. Carboplatin and Paclitaxel in the First Line Treatment of Patients With Recurrent or Metastatic Pancreatic Cancer.
wild-type reovirus; carboplatin; paclitaxel

Pancreatic Cancer Clinical Trial using on-site pathologist; off-site pathologist

Florida Hospital - Recruiting 18 years to 89 years.
- Comparison of On-Site Verus Off-Site Evaluation of Cholangioscopy-Guided Biopsies of the Bile Duct.
on-site pathologist; off-site pathologist

Tumors, Pancreatic Cancer, Non-small Cell Lung Cancer, or Esophag Clinical Trial using GS-5745 monotherapy and in combination with chemotherapy

Gilead Sciences - Recruiting 18 years or older.
- A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5745 as Monotherapy and in Combination With Chemotherapy in Subjects With Advanced Solid Tumors.
GS-5745 monotherapy and in combination with chemotherapy

Patients With Unresectable Nonmetastatic Locally Advanced Pancrea Clinical Trial using Gemcitabine 1000 mg/m2; Oxaliplatin 100 mg/m2; Hypofractionated radiotherapy (35 Gy in 7 fractions)

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori - Recruiting 18 years to 75 years.
- Phase II Study of Hypofractionated Radio-chemotherapy With Gemcitabine Plus Oxaliplatin for Unresectable Nonmetastatic Locally Advanced Pancreatic Cancer..
Gemcitabine 1000 mg/m2; Oxaliplatin 100 mg/m2; Hypofractionated radiotherapy (35 Gy in 7 fractions)

Metastatic Pancreatic Cancer, or Pancreatic Cancer Clinical Trial using IMMU-107; placebo; Gemcitabine

Immunomedics, Inc. - Recruiting 18 years or older.
- An International, Multi-Center, Double-Blind, Randomized, Phase III Trial of 90Y-Clivatuzumab Tetraxetan Plus Low-Dose Gemcitabine Versus Placebo Plus Low-Dose Gemcitabine in Patients With Metastatic (Stage IV) Pancreatic Adenocarcinoma Who Received at Least Two Prior Treatments (PANCRIT-1).
IMMU-107; placebo; Gemcitabine

Metastatic Pancreatic Cancer Clinical Trial using ABI-007; Gemcitabine; simplified LV5FU2

Groupe Cooperateur Multidisciplinaire en Oncologie (GERCOR) - Recruiting 18 years or older.
- Randomized Phase II Study of Weekly ABI-007 Plus Gemcitabine or Simplified LV5FU2 as First-line Therapy in Patients With Metastatic Pancreatic Cancer.
ABI-007; Gemcitabine; simplified LV5FU2

Obstructive Jaundice, or Pancreatic Cancer Clinical Trial using Stent Dysfunction; Complications

Florida Hospital - Recruiting 19 years or older.
- Multicenter Randomized Trial Comparing Covered Metal and Plastic Stents for Preoperative Biliary Decompression in Pancreatic Cancer.
Stent Dysfunction; Complications

Patients Must Have Previously Untreated Apparently Resectable Ade Clinical Trial using Paricalcitol

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Randomized Pilot/Pharmacodynamic/Genomic Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer.
Paricalcitol

Metastatic Pancreatic Cancer Clinical Trial using mFOLFIRINOX

Sun Yat-sen University - Recruiting 18 years to 65 years.
- Phase ? Trial to Investigate the Efficacy and Safety of mFOLFIRINOX in Patients With Metastatic Pancreatic Cancer in China.
mFOLFIRINOX

Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer, Perito Clinical Trial using Narrow Band Imaging (NBI)

Memorial Sloan-Kettering Cancer Center - Recruiting 19 years or older.
- Narrow Band Imaging (NBI): A Novel Imaging Modality in Minimally Invasive.
Narrow Band Imaging (NBI)

Stage IA Pancreatic Adenocarcinoma, Stage IB Pancreatic Adenocarc Clinical Trial using nab-paclitaxel; gemcitabine

Fudan University - Recruiting 18 years to 75 years.
- A Phase II, Single-arm Study to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients With Pancreatic Cancer After Curative Resection.
nab-paclitaxel; gemcitabine

Pancreatic Cancer Metastatic Clinical Trial using Dasatinib; mFOLFOX6

University of Florida - Recruiting 18 years or older.
- Phase II Study of 5-Fluorouracil, Oxaliplatin Plus Dasatinib (FOLFOX-D) in First-line Metastatic Pancreatic Adenocarcinoma.
Dasatinib; mFOLFOX6

Pancreatic Cancer Clinical Trial using Neoadjuvant chemoradiation; Upfront surgery

Seoul National University Hospital - Recruiting 18 years to 75 years.
- Multicenter Prospective Randomized Phase II/III Study of Neoadjuvant Chemoradiation With Gemcitabine in Patients With Borderline Resectable Pancreatic Cancer.
Neoadjuvant chemoradiation; Upfront surgery

Pancreatic Ductal Adenocarcinoma Clinical Trial using The risk assessment questionnaire; Blood specimens; tumor tissue samples will be requested

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma.
The risk assessment questionnaire; Blood specimens; tumor tissue samples will be requested

Pancreatic Cancer Clinical Trial

Celgene Corporation - Recruiting N/A or older.
- MPACT Extension Study: Multicenter, Survival Data Collection in Subjects Previously Enrolled in Protocol CA046.

Early Pancreatic Neoplasia, or Familial Pancreatic Neoplasia Clinical Trial

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study).

Bile Duct Cancer, or Pancreatic Cancer Clinical Trial using Cox2 inhibitor (Celecoxib)

Seoul National University Hospital - Recruiting 19 years to 70 years.
- Prospective, Randomized, Open-label, Controlled Trial of Cyclooxygenase-2 Inhibitor (Celecoxib; Celebrexr) for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer..
Cox2 inhibitor (Celecoxib)

Metastatic Pancreas Cancer Clinical Trial using 5FU, leucovorin, oxaliplatin; Gemcitabine

AHS Cancer Control Alberta - Recruiting 18 years or older.
- A Multicentre, Randomized, Open Label, Phase III Study of Gemcitabine Versus FOLFOX in the First Line Setting for Metastatic Pancreatic Cancer Patients Using Human Equilibrative Nucleoside Transporter 1 (hENT1) Biomarker Testing..
5FU, leucovorin, oxaliplatin; Gemcitabine

Pancreatic Cancer Clinical Trial

Rauscher, Gregory E., M.D. PA - Recruiting 18 years or older.
- Testing Spectrosense EVA System for Detection of Pancreatic Cancer by Analyzing Volatile Organic Compounds (VOCs) in Exhaled Air.

Pancreatic Cancer Clinical Trial using Gadobutrol

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years or older.
- Functional Magnetic Resonance Imaging of Pancreatic Cancer: a Feasibility and Reproducibility Study.
Gadobutrol

Pancreatic Cancer Clinical Trial using Gadobutrol; [F-18]HX4; Gemcitabine; Radiotherapy; Pancreaticoduodenectomy

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years or older.
- The Role of the Tumor Microenvironment of Pancreatic Cancer to Predict Treatment Outcome.
Gadobutrol; [F-18]HX4; Gemcitabine; Radiotherapy; Pancreaticoduodenectomy

Pancreatic Cancer Clinical Trial using Alcohol Block

Thomas Jefferson University - Recruiting 18 years or older.
- A Randomized, Controlled Trial of Intraoperative Celiac Plexus Neurolysis for Patients With Operable (Resectable and Unresectable) Pancreatic and Periampullary Cancer.
Alcohol Block

Metastatic Pancreatic Cancer Clinical Trial using TL-118

Tiltan Pharma Ltd. - Recruiting 18 years or older.
- .
TL-118

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I Trial of Dinaciclib (SCH727965) and MK-2206 in Metastatic Pancreatic Cancer With an Expansion Cohort in Advanced Pancreatic Cancer.
dinaciclib; Akt inhibitor MK2206; pharmacological study; laboratory biomarker analysis

Pancreatic Cancer Clinical Trial using GVAX pancreatic cancer vaccine; cyclophosphamide

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Randomized Three-arm Neoadjuvant and Adjuvant Feasibility and Toxicity Study of a GM-CSF Secreting Allogeneic Pancreatic Cancer Vaccine Administered Either Alone or in Combination With Either a Single Intravenous Dose or Daily Metronomic Oral Doses of Cyclophosphamide for the Treatment of Patients With Surgically Resected Adenocarcinoma of the Pancreas.
GVAX pancreatic cancer vaccine; cyclophosphamide

Solid Tumors, Untreated Pancreatic Adenocarcinoma, Pancreatic Can Clinical Trial using PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Plexxikon - Recruiting 18 years or older.
- A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX7486 as a Single Agent and in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced Solid Tumors.
PLX7486-TsOH; gemcitabine; nab-Paclitaxel

Breast Cancer, Pancreatic Cancer, Colorectal Cancer, Non-small-ce Clinical Trial using MORAb-066

Morphotek - Recruiting 18 years or older.
- A Phase I Study of the Safety, Tolerability, and PK of MORAb-066, a Humanized Monoclonal Antibody to Human TF, in Patients With Advanced or Metastatic Breast, Pancreatic, Colorectal, or NSCLC (Adenocarcinoma) Malignancies.
MORAb-066

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcin Clinical Trial using alisertib; gemcitabine

University of California, Davis - Recruiting 18 years or older.
- Phase I Study of the Combination of MLN8237 and Gemcitabine in Advanced Solid Tumors With Emphasis on Pancreatic Cancer.
alisertib; gemcitabine

Metastatic Pancreatic Cancer, or Metastatic Colorectal Cancer Clinical Trial using NPC-1C/NEO-102

Precision Biologics, Inc - Recruiting 18 years to 85 years.
- A Phase 1/2A Therapeutic, Open Label, Multi-Center Clinical Trial of NPC-1C, a Chimeric Monoclonal Antibody, in Adults With Recurrent, Locally Advanced Unresectable or Metastatic Pancreatic and Colorectal Cancer After Standard Therapy.
NPC-1C/NEO-102

Pancreatic Adenocarcinoma, or Colorectal Cancer Clinical Trial

Oslo University Hospital - Recruiting N/A or older.
- The Process of Metastasis in Colorectal Cancer Tumour Biology and Prognostic Factors in Pancreatic Cancer.

Pancreatic Cancer Clinical Trial using Blood draw

Dartmouth-Hitchcock Medical Center - Recruiting 18 years or older.
- Assessment of Plasma Ghrelin Levels in Patients With Pancreatic Cancer.
Blood draw

Stage IV Pancreatic Cancer Clinical Trial using nab-paclitaxel; Cisplatin; gemcitabine

Pancreatic Cancer Research Team - Recruiting 18 years or older.
- A Phase 1b/2 Pilot Trial of Nab-Paclitaxel Plus Cisplatin Plus Gemcitabine (Nabplagem) in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma (PDA).
nab-paclitaxel; Cisplatin; gemcitabine

Pancreatic Cancer Clinical Trial using protein expression analysis; western blotting; immunohistochemistry staining method; immunologic technique; laboratory biomarker analysis

Fox Chase Cancer Center - Recruiting N/A or older.
- Pharmacodynamic Study of Fibroblast Activity Protein in Patients With Localized Pancreas Cancer Undergoing Surgical Resection.
protein expression analysis; western blotting; immunohistochemistry staining method; immunologic technique; laboratory biomarker analysis

Local Tumor Spread, Advanced Cancer, Metastasized, Pancreatic Can Clinical Trial using Stent; Biliodigestive anastomosis

Universit„tsklinikum Hamburg-Eppendorf - Recruiting 18 years to 90 years.
- Quality of Life After Bilioenteric Anastomosis in Comparison to Endoscopically Placed Stents in Patients With Unresectable Pancreatic Cancer and Jaundice.
Stent; Biliodigestive anastomosis

Pancreatic Cancer Clinical Trial using Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years to 76 years.
- Pilot Study Evaluating An Allogeneic GM-CSF-Transduced Pancreatic Tumor Cell Vaccine (GVAX) and Low Dose Cyclophosphamide Integrated With Fractionated Stereotactic Body Radiation Therapy (SBRT) and FOLFIRINOX Chemotherapy in Patients With Resected Adenocarcinoma of the Pancreas.
Cyclophosphamide; PANC 10.05 pcDNA-1/GM-Neo and PANC 6.03 pcDNA-1/GM-Neo vaccine; Stereotactic Body Radiation (SBRT); FOLFIRINOX

Pancreatic Adenocarcinoma Clinical Trial using Gemcitabine

University of Tehran - Recruiting 18 years to 80 years.
- EUS-guided Intratumoral Gemcitabine Therapy in Locally Advanced Unresectable Pancreatic Cancer: A Phase 1 Study.
Gemcitabine

Metastatic Pancreatic Adenocarcinoma Clinical Trial using Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Ludwig-Maximilians - University of Munich - Recruiting 18 years to 75 years.
- Phase II Study to Evaluatate the Efficacy of Gemcitabine Plus Erlotinib for RASH-positive Patients With Metastatic Pancreatic Cancer and Friendly Risk Circumstances.
Gemcitabine; Erlotinib; Oxaliplatin; Folinic Acid; Irinotecan; 5-FU

Pancreatic Cancer Stage II, or Pancreatic Cancer Stage III Clinical Trial using Neoadjuvant gemcitabine, capecitabine, and docetaxel; Gemcitabine, capecitabine, docetaxel followed by radiotherapy

Columbia University - Recruiting 18 years or older.
- Phase II Study: Neoadjuvant Gemcitabine, Docetaxel and Capecitabine Followed by Neoadjuvant Radiation Therapy With Gemcitabine and Capecitabine in the Treatment of Stage II and III Pancreatic Adenocarcinoma.
Neoadjuvant gemcitabine, capecitabine, and docetaxel; Gemcitabine, capecitabine, docetaxel followed by radiotherapy

Pancreatic Cancer Clinical Trial using capecitabine; cisplatin; epirubicin; gemcitabine

IRCCS San Raffaele - Recruiting 18 years to 75 years.
- Randomized Phase II-III Trial of Peri- or Post-Operative Chemotherapy in Resectable Pancreatic Adenocarcinoma.
capecitabine; cisplatin; epirubicin; gemcitabine

Adenocarcinoma of the Pancreas, or Metastatic Disease Clinical Trial using AUY922

University Health Network, Toronto - Recruiting 18 years or older.
- A Phase II Single Arm Study of AUY922 in Patients With Metastatic Pancreatic Adenocarcinoma Who Are Resistant to First Line Chemotherapy.
AUY922

Metastatic Pancreatic Cancer Clinical Trial using Erlotinib

Taipei Veterans General Hospital, Taiwan - Recruiting 18 years or older.
- The Role of Epidermal Growth Factor Receptor (EGFR) and the Downstream Gene KRAS in Pancreatic Cancer Patients Receiving Gemcitabine Combined With Erlotinib Therapy.
Erlotinib

Primarily Resectable Pancreatic Cancer Clinical Trial using neoadjuvant Photonradiation

German Cancer Research Center - Recruiting 50 years or older.
- Randomised Phase I/II Trial in Order to Evaluate the Effect of Neoadjuvant Radiation on Tumor Infiltrating T-cells by Neoadjuvant Low-Dose-Radiation Therapy in Primarily Resectable Pancreatic Cancer.
neoadjuvant Photonradiation

Carcinoma, Pancreatic Ductal Clinical Trial using Targeted Therapy Tailored Treatment; Standard Chemotherapy

Grupo Hospital de Madrid - Recruiting 18 years or older.
- Phase II Study of Chemotherapy Selection Based on Therapeutic Targets for the Treatment of Advanced Pancreatic Cancer.
Targeted Therapy Tailored Treatment; Standard Chemotherapy

Pancreatic Cancer Clinical Trial using Positron-Emission Tomography (PET) 18F-FLT

AHS Cancer Control Alberta - Recruiting 18 years or older.
- An Imaging Pilot Study of 18F-fluoro-3'-Deoxy-3'-L-fluorothymidine (18F-FLT) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Who Will be Treated With Gemcitabine.
Positron-Emission Tomography (PET) 18F-FLT

Pancreatic Carcinoma Clinical Trial using Gemzar; Revlimid

Karolinska University Hospital - Recruiting 19 years or older.
- Phase I/II Study of Lenalidomide and Gemcitabine as First-line Treatment in Patients With Locally Advanced or Metastatic Pancreatic Cancer.
Gemzar; Revlimid

Pancreas Cancer Clinical Trial using Lapatinib and Capecitabine

Georgetown University - Recruiting 18 years or older.
- Phase II Study of Lapatinib and Capecitabine in 2nd Line Treatment of Locally Advanced/Metastatic Pancreatic Cancer.
Lapatinib and Capecitabine

Pancreas Cancer Clinical Trial using Secretin Synthetic Human (RG1068)

University Hospital Case Medical Center - Recruiting 18 years or older.
- Evaluation of Efficiency of Secretin-Assisted Computed Tomography Scan and Secretin-Assisted Magnetic Resonance Imaging in Improving Pancreatic Enhancement and Tumor Conspicuity: Prospective Study.
Secretin Synthetic Human (RG1068)

Pancreatic Cancer Clinical Trial using M2ES 7.5mg; M2ES 15mg; M2ES 30mg; M2ES 45mg

Protgen Ltd - Recruiting 18 years to 60 years.
- Phase I Study of M2ES Combined Gemcitabine in Patients With Advanced Pancreatic Cancer.
M2ES 7.5mg; M2ES 15mg; M2ES 30mg; M2ES 45mg

Locally Advanced Pancreatic Cancer, or Metastatic Pancreatic Canc Clinical Trial using gemcitabine; erlotinib; metformin; placebo

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) - Recruiting 18 years to 80 years.
- A Phase II, Randomized, Placebo Controlled Study to Evaluate the Efficacy of the Combination of Gemcitabine, Erlotinib and Metformin in Patients With Locally Advanced and Metastatic Pancreatic Cancer.
gemcitabine; erlotinib; metformin; placebo

Pancreatic Cancer Clinical Trial using percutaneous fluoro guided celiac plexus neurolysis; EUS guided neurolysis

Asian Institute of Gastroenterology, India - Recruiting 18 years to 75 years.
- A Randomized Trial Comparing Fluoroscopy Guided Percutaneous Technique Versus Endoscopic Ultrasound Guided Technique of Celiac Plexus Neurolysis for Treatment of Pain in Carcinoma Pancreas.
percutaneous fluoro guided celiac plexus neurolysis; EUS guided neurolysis

Pancreatic Cancer Clinical Trial using efavirenz; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Trial to Assess the Efficacy of Efavirenz as Second-line Monotherapy for the Treatment of Advanced Pancreatic Adenocarcinomas..
efavirenz; quality-of-life assessment

Pancreas Neoplasms Clinical Trial using Docetaxel; Oxaliplatin

University of Ulm - Recruiting 18 years or older.
- Phase II Study: Docetaxel Plus Oxaliplatin as Second-line Therapy in Patients With Advanced Metastatic Pancreatic Cancer.
Docetaxel; Oxaliplatin

Locally Advanced Pancreatic Cancer Clinical Trial using Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino

Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente - Recruiting 18 years to 75 years.
- A Randomized Phase II Study of Gemcitabine/Cisplatin With or Without Sorafenib to Evaluate the Efficacy and Safety in Patients With Locally Advanced or Metastatic Pancreatic Cancer. MAPS Trial.
Sorafenib 400 mg po bid, continuously; Gemcitabina, Cisplatino

Pancreatic Cancer Clinical Trial using Gemcitabine; Curcumin; Celebrex

Tel-Aviv Sourasky Medical Center - Recruiting 18 years or older.
- .
Gemcitabine; Curcumin; Celebrex

Malignant Melanoma, Pancreatic Cancer, Colon Cancer, or Cervical Clinical Trial using Survivin peptide vaccine

Julius-Maximilians University - Recruiting 19 years to 90 years.
- Vaccination of Patients With Advanced Melanoma, Pancreatic, Colon and Cervical Cancer With HLA-A1, -A2 and -B35 Restricted Survivin Peptides.
Survivin peptide vaccine

Gastric Cancer, Esophageal Cancer, Pancreatic Cancer, or Colon Ca Clinical Trial using S-1

Hamamatsu University - Recruiting 20 years to 85 years.
- Pharmacokinetic and Pharmacodynamic Study of S-1 and Its Effects in Patients With the Digestive Organ Cancer With Reference to Genetic Polymorphism and Activity of CYP2A6 and DPD.
S-1