66 results found.

Parkinson's Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and Schizophrenia.

Parkinson's Disease, Essential Tremor, or Dystonia Clinical Trial using Deep Brain Stimulation

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Deep Brain Stimulation Surgery for Movement Disorders.
Deep Brain Stimulation

Idiopathic Parkinson's Disease Clinical Trial

UCB, Inc. - Recruiting N/A or older.
- A Multicenter, Non-interventional Study With Neupro® to Evaluate the Perception of Pain Associated With Idiopathic Parkinson's Disease.

Idiopathic Parkinson's Disease Clinical Trial using Rotigotine; Placebo Patch

UCB, Inc. - Recruiting 20 years or older.
- Double Blind, Placebo-controlled, Parallel, Multicenter, Randomized Interventional Phase IV Study to Evaluate the Efficacy of Rotigotine in Depressive Symptoms in Idiopathic Parkinson's Disease Patients.
Rotigotine; Placebo Patch

Idiopathic Parkinson's Disease Clinical Trial using Rotigotine; Placebo Patch

UCB, Inc. - Recruiting 30 years or older.
- A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Study of The Efficacy And Safety of Rotigotine Transdermal Patch In Chinese Subjects With Advanced-stage, Idiopathic Parkinson's Disease Who Are Not Well Controlled On Levodopa.
Rotigotine; Placebo Patch

Parkinson's Disease Clinical Trial using active light therapy : Light therapy: DayVia lamp 10000 lux; Placebo light therapy

University Hospital, Strasbourg, France - Recruiting 45 years to 75 years.
- Light Therapy in Parkinson's Disease : Effect on Motor Symptoms, Sleep, Circadian Rhythms, and Mood.
active light therapy : Light therapy: DayVia lamp 10000 lux; Placebo light therapy

Parkinson's Disease Clinical Trial using Rasagiline; Placebo

Teva Pharmaceutical Industries - Recruiting 45 years to 80 years.
- A 24-Week, Multicenter, Randomized, Double-blind, Placebo-Controlled, Add-on, Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease.
Rasagiline; Placebo

Parkinson's Disease Clinical Trial using Deep Brain Stimulation (DBS)

Boston Scientific Corporation - Recruiting 18 years or older.
- Registry of Deep Brain Stimulation With the VERCISET System: Vercise DBS Registry.
Deep Brain Stimulation (DBS)

Parkinson's Disease Clinical Trial using Convection enhanced delivery/AAV2-GDNF

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects With Advanced Parkinson's Disease.
Convection enhanced delivery/AAV2-GDNF

Parkinson Disease, or Multiple System Atrophy Clinical Trial using Intranasal Insulin

University of Massachusetts, Worcester - Recruiting 18 years or older.
- A Double-blinded Placebo-controlled Single-center Study to Evaluate the Efficacy of Intranasal Insulin 40 International Units Day as Treatment for Subjects With Parkinson Disease and Multiple System Atrophy.
Intranasal Insulin

Parkinson Disease Clinical Trial

Chang Gung Memorial Hospital - Recruiting 40 years to 80 years.
- Diagnosis of Parkinson's Disease Using Diffusion Magnetic Resonance Imaging.

Movement Disorders, or Parkinson's Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- A Longitudinal Study Assessing the Pathophysiology of Movement Disorders Utilizing the QMAT at Home Testing Device.

Parkinson Disease, Autonomic Nervous System Diseases, or Pure Aut Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- Biomarkers of Risk of Parkinson Disease.

Parkinson's Disease, or Essential Tremor Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders.

Parkinson's Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 80 years.
- Metabolic Phenotyping of Subjects With Mutations Associated With Hereditary Parkinson's Disease.

Parkinson's Disease Clinical Trial using biweekly treatment intervention

Zia, Al Raza - Recruiting 18 years or older.
- Effect on Parkinson's Disease After Therapeutic Induction of CranioSacral Integrated Therapy.
biweekly treatment intervention

Parkinson's Disease Clinical Trial using Transcranial Magnetic Stimulation (TMS)

University of Florida - Recruiting 18 years to 80 years.
- Evaluating Cortical Physiology Following Unilateral and Bilateral Subthalamic Deep Brain Stimulation in Parkinson's Disease.
Transcranial Magnetic Stimulation (TMS)

Parkinson's Disease Clinical Trial using Osteopathic Manipulative Medicine Treatment; Light Touch sham

New York Institute of Technology - Recruiting 18 years or older.
- Effect of Osteopathic Manipulative Medicine on Pulmonary Function and Speech in Parkinson's Disease.
Osteopathic Manipulative Medicine Treatment; Light Touch sham

Parkinson's Disease Clinical Trial using ExAblate Transcranial MRgFUS; Sham ExAblate Transcranial MRgFUS

InSightec - Recruiting 30 years or older.
- A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate Transcranial MR Guided Focused Ultrasound for Unilateral Thalamotomy in the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease..
ExAblate Transcranial MRgFUS; Sham ExAblate Transcranial MRgFUS

Parkinson's Disease Clinical Trial

National Parkinson Foundation - Recruiting N/A or older.
- National Parkinson Foundation Quality Improvement Initiative.

Parkinson Disease Clinical Trial

Seoul National University Hospital - Recruiting N/A or older.
- Temporal Relationship Between Motor Fluctuations and Nonmotor Fluctuations.

Parkinson's Disease, or HIV Infections Clinical Trial

KineMed - Recruiting 18 years or older.
- Cellular and Molecular Kinetics of Cerebrospinal Fluid (CSF) Using Heavy Water Labeling Method: A Study of Healthy Controls, CNS HIV Infection, Parkinson's Disease and Other Neurodegenerative Diseases.

Parkinson's Disease Clinical Trial using LY03003; Neupro

Luye Pharma Group Ltd. - Recruiting 18 years or older.
- A Randomized, Double-blinded, Multiple Ascending Dose Study in Patients With Early-stage Parkinson's Disease to Evaluate the Pharmacokinetics and Safety of LY03003 Following Intramuscular Injections.
LY03003; Neupro

Parkinson's Disease, Tremor, or Bradykinesia Clinical Trial using Automated Programming

Great Lakes NeuroTechnologies Inc. - Recruiting 18 years or older.
- DBS-Expert: Automated Deep Brain Stimulation Programming Using Functional Mapping - Phase I.
Automated Programming

Parkinson's Disease Clinical Trial using Glycerol Phenylbutyrate

University of Colorado, Denver - Recruiting 21 years to 80 years.
- Phenylbutyrate Response As a Biomarker for Alpha-Synuclein Clearance From Brain.
Glycerol Phenylbutyrate

Parkinson's Disease Clinical Trial

Rush University Medical Center - Recruiting 30 years to 90 years.
- Lipopolysaccharide Binding Protein as a Potential Biomarker of Parkinson's Disease.

Idiopathic Parkinson's Disease Clinical Trial

University of Saskatchewan - Recruiting N/A or older.
- Vascular Abnormalities in Idiopathic Parkinson's Disease.

Parkinson's Disease Clinical Trial

New York University School of Medicine - Recruiting 21 years or older.
- Psychiatric and Cognitive Manifestations of Parkinson's Disease: A Prospective Cohort Study.

Parkinson's Disease, or Mild Cognitive Impairment Clinical Trial using Memory and Problem-Solving Intervention; Supportive Therapy

Virginia Commonwealth University - Recruiting 18 years or older.
- A Randomized Controlled Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease.
Memory and Problem-Solving Intervention; Supportive Therapy

Parkinson's Disease Clinical Trial using Florbetapir F-18

Chang Gung Memorial Hospital - Recruiting 20 years to 80 years.
- Imaging Non-motor Symptoms of Parkinson's Disease by Novel 18F-DTBZ and Florbetapir F-18 PET.
Florbetapir F-18

Parkinson's Disease Clinical Trial using PET

Hospices Civils de Lyon - Recruiting 40 years to 70 years.
- Pathophysiology of Non Motor Signs and Compensatory Mechanisms in Parkinson's Disease: Role of the Serotoninergic and Dopaminergic Lesions Studied by PET.
PET

Gastroparesis Clinical Trial using GSK962040 (25 mg tablet); Placebo

GlaxoSmithKline - Recruiting 40 years to 80 years.
- A Randomized, Double-blind, Placebo-controlled, Parallel Group, Dose Ranging Study to Assess the Effect of Repeat Doses of GSK962040 on the Pharmacokinetics of L-DOPA in Subjects With Parkinson's Disease Exhibiting Delayed Gastric Emptying.
GSK962040 (25 mg tablet); Placebo

Idiopathic Parkinson's Disease Clinical Trial using Istradefylline 40 mg; Istradefylline 20 mg; Placebo

Kyowa Hakko Kirin Pharma, Inc. - Recruiting 30 years or older.
- A Phase 3, 12-week, Double-Blind, Placebo-Controlled, Randomized, Multicenter Study to Evaluate the Efficacy of Oral Istradefylline 20 and 40 mg/Day as Treatment for Subjects With Moderate to Severe Parkinson's Disease.
Istradefylline 40 mg; Istradefylline 20 mg; Placebo

Parkinson Disease Clinical Trial

Department of Veterans Affairs - Recruiting 21 years to 95 years.
- CSP #468F - Long Term Study of Deep Brain Stimulation for Parkinson's Disease: A Longitudinal Follow-Up Study of the VA/NINDS CSP #468 Cohort.

Parkinson's Disease Clinical Trial using Rifaximin

Mayo Clinic - Recruiting 18 years or older.
- Weight Loss in Parkinson's Disease and the Potential Role of Small Bowel Bacterial Overgrowth.
Rifaximin

Parkinson's Disease Clinical Trial using rhythmic auditory stimulation

Chang Gung University - Recruiting 20 years or older.
- .
rhythmic auditory stimulation

Parkinson's Disease Clinical Trial using DBS stimulator setting alteration; virtual reality simulator

University of Alabama at Birmingham - Recruiting 19 years or older.
- The Effect of Low Frequency STN DBS on Sleep and Vigilance in PD Patients.
DBS stimulator setting alteration; virtual reality simulator

Parkinson's Disease Clinical Trial using Oxaloacetate (OAA); Placebo

University of Kansas - Recruiting 30 years or older.
- A Pilot Double-Blind, Parallel Group, Placebo Controlled Study of Oxaloacetate in Subjects With Treated Parkinson's Disease (PD).
Oxaloacetate (OAA); Placebo

Parkinson's Disease Clinical Trial

University of Miami - Recruiting 18 years to 65 years.
- Fatigue and Cardiac Sympathetic Denervation in Parkinson Disease.

Parkinson's Disease Clinical Trial using Pramipexole / Rasagiline Mesylate once daily; Placebo

Pharma Two B Ltd. - Recruiting 35 years to 75 years.
- A Phase 2B, Twelve-week Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study, To Determine the Safety, Tolerability and Efficacy of Two Doses of Once Daily P2B001 in Subjects With Early Parkinson's Disease.
Pramipexole / Rasagiline Mesylate once daily; Placebo

Parkinson's Disease Clinical Trial

AbbVie - Recruiting 18 years or older.
- Levodopa Carbidopa Intestinal Gel Home Titration Using Telemedicine: Evaluation of Use of Resources.

Parkinson's Disease Clinical Trial

University of Texas Southwestern Medical Center - Recruiting 30 years or older.
- Longitudinal, Single-center Prospective Study to Assess Progression of Clinical Features and Biologic Markers of Parkinson's Disease Subjects of Varying Levels of Disease Severity.

Parkinson's Disease Clinical Trial using RM-131; Placebo

Rhythm Pharmaceuticals, Inc. - Recruiting 18 years to 80 years.
- A Phase 2, Randomized, Double-blind, Placebo-controlled, Multiple Dose, Parallel Group Study to Evaluate the Pharmacodynamics, Efficacy and Safety of RM-131 Administered to Patients With Parkinson's Disease and Chronic Constipation Dissatisfied With Current Therapy.
RM-131; Placebo

Parkinson's Disease Clinical Trial

Bastyr University - Recruiting 18 years or older.
- Cannabis and Parkinson's Disease Tremor: A Natural History Study.

Advanced Parkinson's Disease Clinical Trial using ABT-SLV187

AbbVie - Recruiting 30 years or older.
- An Open-Label, Single-Arm, Baseline-Controlled, Multicenter Study to Evaluate the Efficacy, Safety and Tolerability of ABT-SLV187 Monotherapy in Subjects With Advanced Parkinson's Disease and Persistent Motor-Complications Despite Optimized Treatment With Available Anti-Parkinsonian Medications.
ABT-SLV187

Parkinson's Disease Clinical Trial

AbbVie - Recruiting 18 years or older.
- Analysis of MOtor and NOn Motor Symptoms, Quality of Life and Occurence of Dyskinesias in Advanced Parkinson's Disease Patients With 2 to 4 Hours 'Off-time' and Without Troublesome Dyskinesias Under Duodopa TREATment - a Multi-country Post-marketing Observational Study -MONOTREAT.

Advanced Parkinson's Disease Clinical Trial using Levodopa-Carbidopa Intestinal Gel

AbbVie - Recruiting 30 years or older.
- An Open-Label, Two Part, Multicenter Study to Assess the Safety and Efficacy of Levodopa Carbidopa Intestinal Gel (LCIG) for the Treatment of Non-Motor Symptoms in Subjects With Advanced Parkinson's Disease.
Levodopa-Carbidopa Intestinal Gel

Parkinson's Disease Clinical Trial

AbbVie - Recruiting 18 years or older.
- Global REsponsE During iNFusIon of a gEl With LevoDopa/Carbidopa (GREENFIELD).

Essential Tremor, Parkinson's Disease, or Dystonia Clinical Trial using WINCS (Wireless Instantaneous Neurochemical Concentration Sensing System)

Mayo Clinic - Recruiting 18 years to 90 years.
- Neurotransmitter Measurements Using Wireless Instantaneous Neurotransmitter Concentration System (WINCS) During Deep Brain Stimulation Neurosurgery..
WINCS (Wireless Instantaneous Neurochemical Concentration Sensing System)

Parkinson Disease Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Expanding the Phenotype of the LRRK-2 Mutation in Individuals With History of Parkinson s Disease and Their Relatives: a Prospective Study.

Parkinson Disease, or Accidental Falls Clinical Trial using Vitamin D; calcium; Placebo

Department of Veterans Affairs - Recruiting 50 years or older.
- The Effects of Vitamin D on Balance in Persons With PD.
Vitamin D; calcium; Placebo

Parkinson's Disease Clinical Trial using PD, DBS

University of Chicago - Recruiting 45 years or older.
- Effects of the Stimulation Frequency of STN DBS on Swallowing Function in Patients With Parkinson's Disease.
PD, DBS

Healthy, Mood Disorder, Parkinson's Disease, or Schizophrenia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers With 3.0 Tesla MRI and Magnetoencephalography.

Parkinsons's Disease Clinical Trial using Continuous Apomorphine infusion; Usual dopaminergic per os treatment

Rennes University Hospital - Recruiting 18 years or older.
- Prospective, Randomised, Comparative Study Comparing Efficacy of Continuous Apomorphine Infusion Versus Usual Dopaminergic Per os Treatment on Cognitive and Neuropsychological Functions in Parkinson's Disease: a Clinical and PET-scan Study.
Continuous Apomorphine infusion; Usual dopaminergic per os treatment

Parkinson's Disease, or Cognitive Impairment Clinical Trial using Atomoxetine; Placebo

Medical University of South Carolina - Recruiting 35 years to 75 years.
- Atomoxetine Treatment for Cognitive Impairment in Parkinson's Disease (ATM-Cog).
Atomoxetine; Placebo

Parkinson Disease, or Cognitive Impairment Clinical Trial

University of Washington - Recruiting 18 years or older.
- Pacific Northwest Udall Center (PANUC) Clinical Core.

Parkinson Disease Clinical Trial using Varenicline; Sugar pill

Rush University Medical Center - Recruiting 40 years to 90 years.
- Varenicline for the Treatment of Postural and Gait Dysfunction in Parkinson Disease.
Varenicline; Sugar pill

Parkinson's Disease Clinical Trial using Deep brain stimulation of the subthalamic nucleus

Oslo University Hospital - Recruiting 18 years to 75 years.
- Prognostic Factors in Parkinson's Disease Patients Treated With Deep Brain Stimulation of the Subthalamic Nucleus (STN-DBS) - a Prospective Randomized Double-blind Study (The NORSTIM Study).
Deep brain stimulation of the subthalamic nucleus

Alzheimer Disease, Stroke, Parkinson's Disease, Lewy Body Dementi Clinical Trial using Computerized tests and Electrophysiological measurements

Centre Hospitalier Universitaire, Amiens - Recruiting 18 years to 85 years.
- Assessment of Social-emotional Functioning in Stroke, Frontotemporal Dementia, Alzheimer and Parkinson Diseases.
Computerized tests and Electrophysiological measurements

Parkinson's Disease Clinical Trial

Washington University School of Medicine - Recruiting 40 years to 70 years.
- Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in PD Without Dementia.

Parkinson's Disease, Depression, or Anxiety Clinical Trial

Washington University School of Medicine - Recruiting 40 years or older.
- Mapping Mood in the Subthalamic Nucleus in PD.

Parkinson's Disease Clinical Trial using placebo; rasagiline

Istanbul University - Recruiting N/A or older.
- The Effects of Rasagiline on Cognitive Deficits Associated With Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study Over 3 Months.
placebo; rasagiline