42 results found.

Pneumonia, or Blood Stream Infection Clinical Trial using colistin and meropenem; colistin and placebo

Kaye, Keith, M.D., M.P.H. - Recruiting 18 years to 95 years.
- Randomized Controlled Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli.
colistin and meropenem; colistin and placebo

Community Acquired Respiratory Disease Syndrome Clinical Trial using Methylprednisolone

Department of Veterans Affairs - Recruiting 18 years or older.
- CSP #574 - Extend Steroid (in) CAP(e) (ESCAPe): A Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Evaluate the Safety and Efficacy of Methylprednisolone in Hospitalized Veterans With Severe Community-Acquired Pneumonia.
Methylprednisolone

Ventilator Associated Pneumonia (VAP), Infection, Antibiotic-Asso Clinical Trial using L. rhamnosus GG - Probiotic

McMaster University - Recruiting 18 years or older.
- Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial.
L. rhamnosus GG - Probiotic

Mechanical Ventilation for More Than 48 Hours Clinical Trial using 0.12% chlorhexidine solution; Placebo

Sinaloa Pediatric Hospital - Recruiting 1 Month to 18 years.
- Chlorhexidine Gluconate for Prevention of Ventilator Associated Pneumonia in a Pediatric Intensive Care Unit..
0.12% chlorhexidine solution; Placebo

Respiratory Tract Infection, Bronchitis, Bronchiolitis, or Pneumo Clinical Trial using xTAG RVP v3

Luminex Molecular Diagnostics - Recruiting N/A or older.
- A Two Arm, Multi-Centre Clinical Evaluation of the xTAG Respiratory Viral Panel v3 Test in Patients With Clinical Signs and Symptoms of Respiratory Tract Infection.
xTAG RVP v3

Rapid Sequence Induction of General Anesthesia, Sellick Maneuver, Clinical Trial using effective sellick maneuver; sham sellick maneuver

Assistance Publique - Hôpitaux de Paris - Recruiting 18 years or older.
- Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial.
effective sellick maneuver; sham sellick maneuver

Nosocomial Pneumonia (NP),, or Ventilator-associated Pneumonia (V Clinical Trial using ceftazidime-avibactam; meropenem

AstraZeneca - Recruiting 18 years to 90 years.
- A Phase III, Randomized, Multicentre, Double-blind, Double-dummy, Parallel-group Comparative Study to Determine the Efficacy, Safety And Tolerability of Ceftazidime-Avibactam Versus Meropenem in the Treatment of Nosocomial Pneumonia Including Ventilator-Associated Pneumonia in Hospitalized Adults.
ceftazidime-avibactam; meropenem

Community-acquired Bacterial Pneumonia Clinical Trial using Solithromycin; Moxifloxacin

Cempra Pharmaceuticals - Recruiting 18 years or older.
- A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxifloxacin in the Treatment of Adult Patients With Community-Acquired Bacterial Pneumonia.
Solithromycin; Moxifloxacin

Severe Pneumonia Clinical Trial

Asan Medical Center - Recruiting 16 years or older.
- Detection and Characterization of Lower Respiratory Infections in Critically Ill Patients.

Pneumonia, Bacterial Clinical Trial using Amikacin Inhalation Solution (BAY41-6551); Aerosolized Placebo

Bayer - Recruiting 18 years or older.
- A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of BAY 41-6551 as Adjunctive Therapy in Intubated and Mechanically-Ventilated Patients With Gram-Negative Pneumonia.
Amikacin Inhalation Solution (BAY41-6551); Aerosolized Placebo

Pneumonia Clinical Trial using Tested Surplus Clinical Specimens

Curetis AG - Recruiting 18 years or older.
- Detection of Microorganisms and Antibiotic Resistance Genes in Lower Respiratory Tract (LRT) Samples, Using the Curetis UnyveroTM LRT Application.
Tested Surplus Clinical Specimens

BSI Due to CRE, or Nosocomial Pneumonia Due to CRE Clinical Trial using plazomicin; colistin; meropenem; tigecycline

Achaogen, Inc. - Recruiting 18 years to 85 years.
- A Phase 3, Multicenter, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE).
plazomicin; colistin; meropenem; tigecycline

Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Interst Clinical Trial using Aerobic Exercise Training

National Institutes of Health Clinical Center (CC) - Recruiting 21 years to 80 years.
- The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease.
Aerobic Exercise Training

HIV, Respiratory Infections, Fungal Pneumonia, Viral Pneumonia, o Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years or older.
- Multiplex Microarray Chip-Based Diagnosis of Respiratory Infections.

Pneumocystis Pneumonia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 3 years or older.
- Studies of Human Pneumocystis Infection.

Community Acquired Pneumonia Clinical Trial using BPS; Guideline

Hospital General de Ni¤os Pedro de Elizalde - Recruiting 3 Months to 5 years.
- Efficacy of BPS (Bacterial Pneumonia Score) Guided Antibiotic Use in Children With Community Acquired Pneumonia on Reducing Antibiotic Use as Compared to Standard Care Practice (Current Guidelines for CAP) in the Era of Pneumococcal Vaccine.
BPS; Guideline

Community-acquired Bacterial Pneumonia Clinical Trial using Solithromycin; Moxifloxacin

Cempra Pharmaceuticals - Recruiting 18 years or older.
- A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in the Treatment of Adult Patients With Community-Acquired Bacterial Pneumonia.
Solithromycin; Moxifloxacin

Lung Cancer, Tuberculosis, Bronchiectasis, Pneumonia, Acute Bronc Clinical Trial using Chest X-ray; computed tomography of the chest; Bronchoscopy

University of Milan - Recruiting 18 years or older.
- Multicenter, Prospective, Observational Study on Epidemiology and Diagnosis of Haemoptysis.
Chest X-ray; computed tomography of the chest; Bronchoscopy

Pneumonia, Pneumococcal Infection, or Pathogen Resistance Clinical Trial using Colistimethate (Colistin)Sodium-Intravenous; Colistimethate (Colistin)Sodium-Aerosolized

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 18 years to 45 years.
- A Phase 1, Open-Labeled Study of the Safety, Tolerability and Pharmacokinetics of Aerosolized Colistimethate Sodium After Multiple Doses Administered Separately or in Combination With Intravenous Colistimethate Sodium in Healthy Adults.
Colistimethate (Colistin)Sodium-Intravenous; Colistimethate (Colistin)Sodium-Aerosolized

Pneumonia, Bacterial Clinical Trial using Ciprofloxacin (Cipro, BAYQ3939)

Bayer - Recruiting 20 years or older.
- A Prospective, Non-randomized, Open-label, Non-controlled, Multicenter Study to Evaluate the Safety, Efficacy and Pharmacokinetics/ Pharmacodynamics of BAYQ3939 (400 mg BID and 400 mg TID) in Hospitalized Patients With Severe Bacterial Pneumonia or Bacterial Pneumonia With a Poor Response to Other Antimicrobials.
Ciprofloxacin (Cipro, BAYQ3939)

Pneumonia, Bacterial Clinical Trial using Amikacin Inhalation Solution (BAY41-6551); Aerosolized Placebo

Bayer - Recruiting 18 years or older.
- A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of BAY 41-6551 as Adjunctive Therapy in Intubated and Mechanically-Ventilated Patients With Gram-Negative Pneumonia.
Amikacin Inhalation Solution (BAY41-6551); Aerosolized Placebo

Pneumonia, or Peritonitis Clinical Trial

University of Oxford - Recruiting 18 years or older.
- Functional Genomic Influences on Disease Progression and Outcome in Sepsis Due to Pneumonia or Peritonitis.

Bone Marrow Transplant Infection, Infection in Marrow Transplant Clinical Trial using Ribavirin

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- An Open Label Randomized Controlled Trial To Prevent the Progression of Respiratory Syncytial Virus Upper Respiratory Tract Infection to Lower Respiratory Tract Infection in Patients After Hematopoietic Stem Cell Transplant.
Ribavirin

Pneumonia Clinical Trial using Lung Ultrasound; Chest X-Ray

Mount Sinai School of Medicine - Recruiting N/A or older.
- Comparative Effectiveness of Lung Ultrasound vs. Chest X-ray for the Diagnosis of Pneumonia in the Emergency Department.
Lung Ultrasound; Chest X-Ray

Pneumocystis Jiroveci Pneumonia Clinical Trial

National Taiwan University Hospital - Recruiting 20 years or older.
- A Pharmacokinetic and Pharmacogenetic Study in Patients Receiving Sulfamethoxazole-trimethoprim Therapy.

Pneumonia, Bacterial Clinical Trial using Amikacin fosfomycin inhalation solution; Aerosolized placebo

Cardeas Pharma - Recruiting 18 years to 80 years.
- A Randomized Blinded, Placebo-Controlled, Phase 2 Study of Aerosolized Amikacin and Fosfomycin Delivered Via the Investigational eFlowr Inline System in Mechanically Ventilated Patients With Gram-negative Bacterial Pneumonia (IASIS).
Amikacin fosfomycin inhalation solution; Aerosolized placebo

Pneumonia Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting N/A or older.
- Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage From Patients With Lung Infiltrates.

Infections, or Community Acquired Pneumonia Clinical Trial using Ceftaroline fosamil; Ceftriaxone; amoxicillin clavulanate

Cerexa, Inc. - Recruiting 2 Months to 18 years.
- A Multicenter, Randomized, Observer-Blinded, Active-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Ceftaroline Versus Ceftriaxone in Pediatric Subjects With Community-acquired Bacterial Pneumonia Requiring Hospitalization.
Ceftaroline fosamil; Ceftriaxone; amoxicillin clavulanate

Infections, or Pneumonia Clinical Trial using Ceftaroline fosamil; IV Ceftriaxone and Vancomycin

Cerexa, Inc. - Recruiting 2 Months to 18 years.
- A Multicenter, Randomized, Observer-Blinded, Active-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Ceftaroline Versus Ceftriaxone Plus Vancomycin in Pediatric Subjects With Complicated Community-acquired Bacterial Pneumonia (CABP).
Ceftaroline fosamil; IV Ceftriaxone and Vancomycin

Pneumonia Clinical Trial using TR-701 FA IV; Linezolid

Cubist Pharmaceuticals - Recruiting 18 years or older.
- A Phase 3 Randomized Double-blind Study Comparing TR-701 FA and Linezolid in Ventilated Gram-positive Nosocomial Pneumonia.
TR-701 FA IV; Linezolid

Pneumonia Clinical Trial using Lung sound analyzer

RWTH Aachen University - Recruiting 18 years to 90 years.
- Monitoring of Lung Sounds of Patients With Pneumonia.
Lung sound analyzer

Coagulopathy, or Nosocomial Pneumonia Clinical Trial using Vitamin C; Vitamin E; Saline (for Vitamin C); Placebo (for Vitamin E)

University of Alabama at Birmingham - Recruiting 19 years or older.
- Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma.
Vitamin C; Vitamin E; Saline (for Vitamin C); Placebo (for Vitamin E)

Ventilator-associated Bacterial Pneumonia Clinical Trial using Colistin; Meropenem

Fundaci¢n P£blica Andaluza para la gesti¢n de la Investigaci¢n en Sevilla - Recruiting 18 years or older.
- Randomized, Open Label, Multicenter, Non-inferiority Trial to Compare Safety and Efficacy of Colistin vs. Meropenem in VAP Caused by CR-GNB.
Colistin; Meropenem

Intensive Care Unit Syndrome, or Community-acquired Pneumonia Clinical Trial using Levofloxacin

University Hospital, Toulouse - Recruiting 18 years or older.
- Population Pharmacokinetics of Levofloxacin in Intensive Care Patients With Severe Community-acquired Pneumonia..
Levofloxacin

Ventilator Associated Pneumonia Clinical Trial using AnapnoGuard 100,; routine mechanical ventilator

Hospitech Respiration - Recruiting 18 years or older.
- Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated ICU Patients Using the AnapnoGuard System.
AnapnoGuard 100,; routine mechanical ventilator

Malaria, Pneumonia, or Diarrhoea Clinical Trial using Technology supported supervision; Community supported supervision; Integrated community case management

Malaria Consortium Africa - Recruiting N/A or older.
- Integrated Community Case Management of Common Childhood Diseases: Mozambique and Uganda.
Technology supported supervision; Community supported supervision; Integrated community case management

Diarrhoea, Malaria, Pneumonia, Breastfeeding, or Under-nutrition Clinical Trial using Local radio campaign to reduce under-five child mortality

London School of Hygiene and Tropical Medicine - Recruiting N/A to 5 years.
- Can Mass Media Campaigns Reduce Child Mortality.
Local radio campaign to reduce under-five child mortality

Community Acquired Pneumonia Clinical Trial using Intervention group; Control group

Hospital Galdakao-Usansolo - Recruiting 18 years or older.
- SUITABILITY OF ANTIBIOTIC TREATMENT FOR COMMUNITY-ACQUIRED PNEUMONIA.
Intervention group; Control group

Ventilator Associated Pneumonia Clinical Trial using lateral-Trendelenburg position

Policlinico Hospital - Recruiting 18 years or older.
- Prospective, Randomized, Multi-Center Trial of Lateral Trendelenburg Versus Semi-Recumbent Body Position in Mechanically Ventilated Patients For The Prevention of Ventilator-Associated Pneumonia.
lateral-Trendelenburg position

Respiratory Tract Infections, Bronchiolitis Obliterans, Cryptogen Clinical Trial using Prednisone; Azithromycin; Montelukast; Symbicort

Maisonneuve-Rosemont Hospital - Recruiting 18 years or older.
- Does Increasing Immunosuppression Prevent Transplant-associated Lung-disease Triggered by Viral Respiratory Tract Infection Following Allogeneic Stem Cell Transplant? A Pilot Study.
Prednisone; Azithromycin; Montelukast; Symbicort

Asthma, Cystic Fibrosis, Chronic Lung Disease, or Pneumonia Clinical Trial

Maastricht University Medical Center - Recruiting 6 years to 18 years.
- Optimising and Standardising Measurements of Inflammatory Markers in Exhaled Breath (EB) and Exhaled Breath Condensate (EBC).

Enterobacteriaceae Infections, Bacteremia, Pneumonia, Skin Diseas Clinical Trial using Risk factors for infections due to ESBL+ Enterobacteriaceae; Risk factors for inadequate initial antimicrobial therapy; Overall and 30-day mortality in bad first antibiotic therapy

University of Siena - Recruiting 16 years or older.
- Infections Caused by Enterobacteriaceae Producing Extended-Spectrum á-Lactamases in Italy: Molecular Epidemiology, Clinical Impact, Treatment Outcome and Risk Factors.
Risk factors for infections due to ESBL+ Enterobacteriaceae; Risk factors for inadequate initial antimicrobial therapy; Overall and 30-day mortality in bad first antibiotic therapy