241 results found.

Prostate Cancer Clinical Trial using Abiraterone Acetate; Prednisone 5 mg twice daily; Prednisone 5 mg once daily; Prednisone 2.5 mg twice daily; Dexamethasone 0.5 mg once daily

Janssen Pharmaceutica N.V., Belgium - Recruiting 18 years or older.
- A Randomized Phase 2 Study Evaluating Abiraterone Acetate With Different Steroid Regimens for Preventing Symptoms Associated With Mineralocorticoid Excess in Asymptomatic, Chemotherapy-naïve and Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients.
Abiraterone Acetate; Prednisone 5 mg twice daily; Prednisone 5 mg once daily; Prednisone 2.5 mg twice daily; Dexamethasone 0.5 mg once daily

Prostate Cancer Clinical Trial using radiation therapy

Swiss Group for Clinical Cancer Research - Recruiting 18 years to 75 years.
- Dose Intensified Salvage Radiotherapy in Biochemically Relapsed Prostate Cancer Without Macroscopic Disease. A Randomized Phase III Trial..
radiation therapy

Glioblastoma Multiforme, Squamous Cell Carcinoma of Head and Neck Clinical Trial using CC-115

Celgene Corporation - Recruiting 18 years or older.
- A Phase 1a/b, Multicenter, Open Label, Dose-Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Dual DNA-PK and TOR Kinase Inhibitor, CC-115, Administered Orally to Subjects With Advanced Solid Tumors, and Hematologic Malignancies..
CC-115

Prostate Cancer Clinical Trial using bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; orteronel; triptorelin

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) With a GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT With a GNRH Agonist and TAK-700 For Men With High Risk Prostate Cancer.
bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; orteronel; triptorelin

Prostate Cancer Clinical Trial using Best Systemic Therapy (BST); Best Systemic Therapy (BST) + Surgery or Radiation Therapy; Questionnaires; Phone Call/Email

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Randomized, Phase II Trial of Best Systemic Therapy or Best Systemic Therapy (BST) Plus Definitive Treatment (Radiation or Surgery) of the Primary Tumor in Metastatic (M1) Prostate Cancer (PC).
Best Systemic Therapy (BST); Best Systemic Therapy (BST) + Surgery or Radiation Therapy; Questionnaires; Phone Call/Email

Prostatic Neoplasms Clinical Trial using VT-122; Placebo

Vicus Therapeutics - Recruiting 18 years or older.
- A Randomized, Placebo Controlled, Multicenter Phase 2 Study of Etodolac and Propranolol in Patients With Clinically Progressive Prostate Cancer.
VT-122; Placebo

Prostate Cancer, Erectile Dysfunction Following Radical Prostatec Clinical Trial using Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Case Comprehensive Cancer Center - Recruiting 21 years or older.
- Improving Erectile Function and Quality of Life After Prostate Cancer Treatment.
Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Prostate Cancer, Castration Resistant Prostate Cancer, Pain, or P Clinical Trial using cabozantinib; mitoxantrone; prednisone

Exelixis - Recruiting 18 years or older.
- A Phase 3, Randomized, Double-blind, Controlled Trial of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer.
cabozantinib; mitoxantrone; prednisone

Prostate Cancer, or Metastatic (Spread to Other Areas of the Body Clinical Trial using BKM120

Duke University - Recruiting 18 years or older.
- Phase II Study of BKM120 in Men With Metastatic Castration-Resistant Prostate Cancer.
BKM120

Prostate Cancer Clinical Trial using tasquinimod; tasquinimod 0.25 mg; 0.5 mg; tasquinimod 0.25 mg; 0.5 mg; 1.0 mg

Duke University - Recruiting 18 years to 79 years.
- The CATCH Prostate Cancer Trial: Cabazitaxel And Tasquinimod in Men With Castration-Resistant Heavily Pre-treated Prostate Cancer.
tasquinimod; tasquinimod 0.25 mg; 0.5 mg; tasquinimod 0.25 mg; 0.5 mg; 1.0 mg

Prostatic Neoplasms Clinical Trial using BAY2010112

Bayer - Recruiting 18 years or older.
- An Open-label, Phase I, Dose-escalation Study to Characterize the Safety, Tolerability, Pharmacokinetics, and Maximum Tolerated Dose of BAY2010112 Given Once Daily by Subcutaneous Administration in Subjects With Castration-resistant Prostate Cancer.
BAY2010112

Prostate Cancer Clinical Trial using GDC-0068; GDC-0980; placebo; abiraterone; prednisone

Genentech - Recruiting 18 years or older.
- A Phase Ib/II Study of GDC-0068 Or GDC-0980 With Abiraterone Acetate Versus Abiraterone Acetate in Patients With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy.
GDC-0068; GDC-0980; placebo; abiraterone; prednisone

Prostate Cancer Clinical Trial using Muscadine Plus Grape Skin Extract

Johns Hopkins University - Recruiting 18 years or older.
- Phase I/II Study of Safety and Efficacy of Muscadine Plus (MPX) in Men With Prostate Cancer: a Randomized,Double-blind,Placebo Controlled Study of the Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer.
Muscadine Plus Grape Skin Extract

Prostate Cancer Clinical Trial using Enzalutamide

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer (CRPC) With Correlative Assessment of Androgen Receptor (AR) Signaling and Whole-exome and Transcriptome Sequencing.
Enzalutamide

Prostate Cancer Clinical Trial using Robot-assisted prostate biopsy

Sidney Kimmel Comprehensive Cancer Center - Recruiting 35 years to 75 years.
- .
Robot-assisted prostate biopsy

Prostatic Neoplasms Clinical Trial using Radium-223 dichloride (Xofigo, BAY88-8223)

Bayer - Recruiting 18 years or older.
- A Re-treatment Safety Study of Radium-223 Dichloride in Subjects With Castration-resistant Prostate Cancer With Bone Metastases Who Received an Initial Course of Six Doses of Radium-223 Dichloride 50 kBq/kg Every Four Weeks.
Radium-223 dichloride (Xofigo, BAY88-8223)

Castrate Resistant Prostate Cancer, Chemotherapy Naive Prostate C Clinical Trial using Pasireotide; Everolimus; Laboratory biomarker analysis

Thomas Jefferson University - Recruiting 18 years or older.
- An Open Label Randomized Phase II Study of SOM230 and Everolimus in Castrate-Resistant, Chemotherapy-Na‹ve Prostate Cancer Patients.
Pasireotide; Everolimus; Laboratory biomarker analysis

Prostate Cancer Clinical Trial using Eovist; MRI Scan; Percutaneous needle biopsy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Pilot Study of Eovist (Gadoxetate) Enhanced MRI for the Detection of Prostate Cancer.
Eovist; MRI Scan; Percutaneous needle biopsy

Prostate Cancer Clinical Trial using Abiraterone acetate; Abiraterone acetate plus degarelix; Degarelix

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase 2, Randomized, 3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy.
Abiraterone acetate; Abiraterone acetate plus degarelix; Degarelix

Prostate Cancer, Radiotherapy, or MRI Clinical Trial using FLAME boost; standard arm

UMC Utrecht - Recruiting 18 years or older.
- FLAME: Single Blind Randomized Phase III Trial to Investigate the Benefit of a Focal Lesion Ablative Microboost in Prostate Cancer.
FLAME boost; standard arm

Prostate Cancer Clinical Trial using Multiparametric MRI; Prostate biopsy

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- A Phase II, Prospective Study of MRI in the Reclassification of Men Considering Active Surveillance in Prostate Cancer.
Multiparametric MRI; Prostate biopsy

Prostatic Neoplasms Clinical Trial using Radium-223 dichloride (Xofigo, BAY88-8223)

Bayer - Recruiting 18 years or older.
- A Single-arm, International, Prospective, Interventional, Open-label, Multicenter Study of Radium-223 Dichloride in the Treatment of Patients With Castration-Resistant Prostate Cancer (CRPC) With Bone Metastasis.
Radium-223 dichloride (Xofigo, BAY88-8223)

Prostate Cancer Clinical Trial using bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; triptorelin; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer.
bicalutamide; buserelin; flutamide; goserelin acetate; leuprolide acetate; triptorelin; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

Castration-resistant Prostate Cancer Clinical Trial using BEZ235; BKM120

Novartis - Recruiting 18 years or older.
- Phase Ib Dose Finding Study of Abiraterone Acetate Plus BEZ235 or BKM120 in Patients With Castration-resistant Prostate Cancer..
BEZ235; BKM120

Metastatic Castrate-Resistant Prostate Cancer (mCRPC),, Efficacy, Clinical Trial using Intermittent dosing of AZD5363

AstraZeneca - Recruiting 18 years or older.
- A Phase Ib Multicentre Study of AZD5363 Monotherapy to Assess Anti-Tumour Activity,Safety,Tolerability,and Pharmacokinetics in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC)(PYRUS).
Intermittent dosing of AZD5363

Prostate Cancer Clinical Trial using Questionnaire

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Radiation Therapy for Rising Prostate Specific Antigen (PSA) Post-prostatectomy.
Questionnaire

Prostate Cancer Clinical Trial using TAK-700; Bicalutamide

Southwest Oncology Group - Recruiting 18 years or older.
- A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 With Androgen Deprivation Therapy + Bicalutamide in Patients With Newly Diagnosed Metastatic Sensitive Prostate Cancer.
TAK-700; Bicalutamide

Prostate Cancer Clinical Trial using Software for acquiring ultrasound and endoscopic images

University Hospital, Grenoble - Recruiting 18 years to 90 years.
- Merging of Endoscopic and Ultrasound Images for Laparoscopic Surgery.
Software for acquiring ultrasound and endoscopic images

Prostate Cancer Clinical Trial using blood draw

Memorial Sloan-Kettering Cancer Center - Recruiting 30 years or older.
- Evaluation of Molecular Forms of PSA and Human Kallikrein 2 in a Cohort of Patients With Locally Resected Prostate Cancer But Biochemical Recurrence.
blood draw

Prostate Cancer Clinical Trial using CyberKnife Stereotactic Ablative Body Radiation Therapy

Riverside Community Hospital, California - Recruiting 18 years or older.
- Prospective Evaluation of CyberKnife Stereotactic Radiosurgery for Low and Intermediate Risk Prostate Cancer.
CyberKnife Stereotactic Ablative Body Radiation Therapy

Prostate Cancer Clinical Trial using PROSTVAC-F/TRICOM; PROSTVAC-V/TRICOM; Enzalutamide (Xtandi)

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase II Trial of Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer.
PROSTVAC-F/TRICOM; PROSTVAC-V/TRICOM; Enzalutamide (Xtandi)

Cervical Cancer, Endometrial Cancer, Esophageal Cancer, Prostate Clinical Trial using Brachytherapy

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- A Natural History Study of Patients Receiving High Dose Rate Brachytherapy.
Brachytherapy

Prostate Cancer Clinical Trial using Ferumoxytol

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Evaluation of Ferumoxytol Enhanced MRI for the Detection of Lymph Node Involvement in Prostate Cancer.
Ferumoxytol

Prostate Cancer Clinical Trial using LHRH; Docetaxel; Conformal RT

Proton Collaborative Group - Recruiting 18 years to 75 years.
- Phase 2/3 Study of Dose-escalated External Beam Radiation Therapy With or Without Chemotherapy for High Risk Adenocarcinoma of the Prostate.
LHRH; Docetaxel; Conformal RT

Prostate Cancer Clinical Trial using Proton Radiation Hypofractionation; Proton Radiation Standard Fractionation

Proton Collaborative Group - Recruiting 18 years or older.
- A Phase III Prospective Randomized Trial of Standard-fractionation vs. Hypo-fractionation With Proton Radiation Therapy for Low Risk Adenocarcinoma of the Prostate.
Proton Radiation Hypofractionation; Proton Radiation Standard Fractionation

Prostate Cancer Clinical Trial using Metformin; Placebo

University Health Network, Toronto - Recruiting 18 years to 79 years.
- A Randomized, Double-Blind, Placebo-Controlled Trial of Metformin in Reducing Progression Among Men on Expectant Management for Low Risk Prostate Cancer: The MAST (Metformin Active Surveillance Trial) Study.
Metformin; Placebo

Prostate Cancer Clinical Trial using Proton Radiation; Androgen Suppression Therapy

Proton Collaborative Group - Recruiting 18 years or older.
- Phase III Study of Mildly Hypo-fractionated Image Guided Proton Beam Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Adenocarcinoma of the Prostate.
Proton Radiation; Androgen Suppression Therapy

Breast Cancer, Healthy Volunteer, or Prostate Cancer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated Skin.

Prostatic Neoplasms Clinical Trial using Cabozantinib; Docetaxel; Prednisone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase I Study of Cabozantinib (XL184) Plus Docetaxel and Prednisone in Metastatic Castrate Resistant Prostate Cancer.
Cabozantinib; Docetaxel; Prednisone

Prostate Cancer Clinical Trial using Fluvastatin; Pimonidazole

University Health Network, Toronto - Recruiting 18 years to 75 years.
- Novel Window of Opportunity Trial to Evaluate the Impact of Statins to Oppose Prostate Cancer.
Fluvastatin; Pimonidazole

Prostate Cancer Metastatic Clinical Trial using CABAZITAXEL (XRP6258); DOCETAXEL (XRP6976); prednisone

Sanofi - Recruiting 18 years or older.
- Phase II Trial to Evaluate Benefit of Early Switch From First-Line Docetaxel/Prednisone to Cabazitaxel/Prednisone and the Opposite Sequence, Exploring Molecular Markers and Mechanisms of Taxane Resistance in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC) Who Have Not Received Prior Chemotherapy.
CABAZITAXEL (XRP6258); DOCETAXEL (XRP6976); prednisone

Prostatic Neoplasms Clinical Trial using Radium-223 dichloride (Xofigo, BAY88-8223)

Bayer - Recruiting 20 years or older.
- A Single-arm, Open-label, Multicenter, Phase II Study of BAY88-8223 in the Treatment of Japanese Patients With Symptomatic Castration-resistant Prostate Cancer (CRPC) With Bone Metastases.
Radium-223 dichloride (Xofigo, BAY88-8223)

Prostate Cancer, Metastatic Prostate Cancer, or Castration-resist Clinical Trial

Astellas Pharma Inc - Recruiting N/A or older.
- A Prospective, Longitudinal, Multinational, Observational Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk for Poor Clinical Outcomes After Experiencing Biochemical Failure Following Definitive Prostate Cancer Therapy, Men With Castration-Resistant Prostate Cancer and Men With Metastatic Prostate Cancer at Initial Diagnosis.

Lung Function Clinical Trial using AirSeal; Olympus UHI-3

Universit„tsklinikum Hamburg-Eppendorf - Recruiting 18 years or older.
- Investigation of the Possible Advantages of the AirSeal-system Compared to Conventional CO2 Insufflation Systems in Terms of Lung Function and Hemodynamics in Robot-assisted Laparoscopic Radical Prostate Ectomy.
AirSeal; Olympus UHI-3

Prostatic Neoplasms Clinical Trial using Radium-223 dichloride (BAY88-8223)

Bayer - Recruiting 18 years or older.
- Radium-223 Dichloride (Alpharadin) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases.
Radium-223 dichloride (BAY88-8223)

Prostate Cancer Clinical Trial using Arm B: Helical Tomotherapy Intensity Modulated Radiotherapy; Arm A: 3D-Conformal Radiation

Ottawa Hospital Research Institute - Recruiting 18 years or older.
- Randomized Phase III Trial of 3D Conformal Radiotherapy Versus Helical Tomotherapy IMRT in High-Risk Prostate Cancer.
Arm B: Helical Tomotherapy Intensity Modulated Radiotherapy; Arm A: 3D-Conformal Radiation

Prostate Cancer Clinical Trial

Washington University School of Medicine - Recruiting 18 years or older.
- Prostate Cancer Prospective Cohort.

Advanced Castrate-resistant Prostate Cancer (CRPC);, Squamous Non Clinical Trial using AZD8186

AstraZeneca - Recruiting 18 years or older.
- A Phase I, Open-label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumour Activity of Ascending Doses of AZD8186 in Patients With Advanced Castrate-resistant Prostate Cancer (CRPC), Squamous Non-Small Cell Lung Cancer (sqNSCLC), Triple Negative Breast Cancer (TNBC) and Patients With Known PTEN-deficient Advanced Solid Malignancies, With Expansion to Assess the Pharmacodynamic Activity of AZD8186 Within Prospectively-validated PTEN Deficient Tumours.
AZD8186

Fallopian Tube, Primary Peritoneal Cancer, or Solid Tumors (eg Br Clinical Trial using ABT-767

AbbVie - Recruiting 18 years or older.
- A Phase 1 Study of ABT-767 in BRCA1 or BRCA2 Mutation Carriers With Advanced Solid Tumors and in Subjects With High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer.
ABT-767

Prostatic Neoplams, Prostate Cancer, Neoplasm, Prostate, or Neopl Clinical Trial using AMG 386; Abiraterone; Prednisone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate Cancer.
AMG 386; Abiraterone; Prednisone

Castrate Resistent Prostate Cancer Clinical Trial using BPX-201 vaccine plus AP1903

Bellicum Pharmaceuticals - Recruiting 18 years or older.
- A Phase I Study of BPX-201 Vaccine Plus AP1903 in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC).
BPX-201 vaccine plus AP1903

Prostate Cancer Clinical Trial using Radiation

New York University School of Medicine - Recruiting 18 years or older.
- Phase I Study of Hypo-Fractionated Radiation Therapy (HRT) for Localized Prostate Cancer.
Radiation

Prostate Cancer Clinical Trial using Fascial suturing; Lymph node template

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- A Randomized Trial of Modifications to Radical Prostatectomy.
Fascial suturing; Lymph node template

Prostate Cancer Clinical Trial using Survey

M.D. Anderson Cancer Center - Recruiting N/A or older.
- Active Surveillance in Prostate Cancer: A Prospective Cohort Study.
Survey

Metastatic Castration-resistant Prostate Cancer, or Metastatic Br Clinical Trial using Abiraterone acetate

Janssen Research & Development, LLC - Recruiting N/A or older.
- A Phase 3b Multicenter, Open-label Abiraterone Acetate Long-term Safety Study.
Abiraterone acetate

Prostate Cancer Clinical Trial using Prostate Biopsy, Focal Brachytherapy , Assessment of QOL

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- Phase II Study Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy Early Stage, Low Volume in Prostate Cancer.
Prostate Biopsy, Focal Brachytherapy , Assessment of QOL

Prostate Cancer Metastatic Clinical Trial using PROSTVAC-V; PROSTVAC-F; GM-CSF; GM-CSF Placebo; Placebo

Bavarian Nordic, Inc. - Recruiting 18 years or older.
- A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer.
PROSTVAC-V; PROSTVAC-F; GM-CSF; GM-CSF Placebo; Placebo

Prostate Cancer Clinical Trial using PROSTVAC-F/TRICOM; PROSTVAC-V/TRICOM; Enzalutamide (Xtandi)

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Randomized Phase II Trial Combining Vaccine Therapy With PROSTVAC /TRICOM and Enzalutamide vs. Enzalutamide Alone in Men With Metastatic Castration Resistant Prostate Cancer.
PROSTVAC-F/TRICOM; PROSTVAC-V/TRICOM; Enzalutamide (Xtandi)

Prostate Cancer Clinical Trial using Everolimus, lupron, bicalutamide, and radiation

University of Michigan Cancer Center - Recruiting 18 years or older.
- A Multi-institutional Phase I and Biomarker Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk Prostate Cancer.
Everolimus, lupron, bicalutamide, and radiation

Prostatic Neoplasms, or Prostate Cancer Clinical Trial

Stanford University - Recruiting 18 years or older.
- Quality of Life Following Radical Prostatectomy.

Prostate Cancer Clinical Trial using AdV-tk + valacyclovir; Placebo + valacyclovir

Advantagene, Inc. - Recruiting 18 years or older.
- A Randomized Controlled Trial of ProstAtakT as Adjuvant to Up-front Radiation Therapy For Localized Prostate Cancer.
AdV-tk + valacyclovir; Placebo + valacyclovir

Prostate Cancer, Metastatic Castrate-Resistant Prostate Cancer, o Clinical Trial using OGX-427; Abiraterone Acetate; Prednisone

Hoosier Oncology Group - Recruiting 18 years or older.
- The Pacific Clinical Trial: A Randomized Phase II Study Evaluating OGX-427 in Patients With Metastatic Castrate-Resistant Prostate Cancer (MCRPC)Who Have Prostate-Specific Antigen (PSA) Progression While Receiving Abiraterone: Hoosier Oncology Group GU12-159.
OGX-427; Abiraterone Acetate; Prednisone

Cancer of Prostate, Cancer of the Prostate, Neoplasms, Prostate, Clinical Trial using sipuleucel-T

Dendreon - Recruiting 18 years or older.
- An Open-Label Study Study of Sipuleucel-T in European Men With Metastatic, Castrate Resistant Prostate Cancer.
sipuleucel-T

Prostatic Neoplasms, or Prostate Cancer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Evaluation of Local Response of Prostate Cancer to Irradiation Using Multiparametric MRI and MR-Guided Biopsies.

Prostate Cancer Clinical Trial using DSTP3086S

Genentech - Recruiting 18 years or older.
- A Phase I, Open-Label Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With Metastatic Castration-Resistant Prostate Cancer.
DSTP3086S

Healthy, no Evidence of Disease, or Prostate Cancer Clinical Trial using selenium; placebo; laboratory biomarker analysis; pharmacological study; Se-methyl-seleno-L-cysteine

National Cancer Institute (NCI) - Recruiting 40 years to 80 years.
- Phase I Multiple Dose Study of 12-Week Treatment by Se-Methyl-L-Cysteine(MSC) and L SeMet in Adult Males.
selenium; placebo; laboratory biomarker analysis; pharmacological study; Se-methyl-seleno-L-cysteine

Prostate Cancer Clinical Trial using MRI examination

Radboud University - Recruiting N/A or older.
- Prostate Cancer Localization With a Multiparametric MR Approach.
MRI examination

Castration-resistant Prostate Cancer Clinical Trial using F-Choline-PET

University Hospital, Grenoble - Recruiting 18 years or older.
- F-choline PET in Early Response Assessment for Castration Resistant Prostatic Cancer Treated by Abiraterone Acetate or Enzalutamide.
F-Choline-PET

Prostate Cancer Clinical Trial using PSMA ADC

Progenics Pharmaceuticals, Inc. - Recruiting 18 years or older.
- A Phase 2, Open-label, Multicenter Study of PSMA ADC in Subjects With Metastatic Castration-resistant Prostate Cancer.
PSMA ADC

Prostate Cancer, or Prostatic Neoplasms Clinical Trial using Panobinostat; Bicalutamide

New York University School of Medicine - Recruiting 18 years or older.
- Phase I/II Randomized Trial of LBH589 (Panobinostat) at Two Dose Levels Combined With Bicalutamide (Casodex) in Men With Castration-resistant Prostate Cancer.
Panobinostat; Bicalutamide

Prostate Neoplasms, or Prostate Cancer Clinical Trial using Cohort 4; Cohort 3; Cohort 2; Cohort 1

Cougar Biotechnology, Inc. - Recruiting 18 years or older.
- A Phase 1b Safety Study of Abiraterone Acetate (JNJ-212082) and Docetaxel in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Cohort 4; Cohort 3; Cohort 2; Cohort 1

Adenocarcinoma of the Prostate, Bone Metastases, Hormone-resistan Clinical Trial using sipuleucel-T; external beam radiation therapy; laboratory biomarker analysis

City of Hope Medical Center - Recruiting 18 years or older.
- Randomized Phase II Trial of Sipuleucel T Immunotherapy Preceded by Sensitizing Radiation Therapy and Sipuleucel-T Alone in Patients With Castrate Resistant Metastatic Prostate Cancer.
sipuleucel-T; external beam radiation therapy; laboratory biomarker analysis

Recurrent Prostate Cancer Clinical Trial using High Intensity Focused Ultrasound

USHIFU, LLC - Recruiting 40 years to 85 years.
- A Multicenter Clinical Study of the Sonablater 450 (Sonablate) for the TreAtment of Locally Recurrent Prostate Cancer With HIFU (STAR Trial).
High Intensity Focused Ultrasound

Prostate Cancer Clinical Trial

Stanford University - Recruiting 18 years to 80 years.
- Photoacoustic Imaging (PAI) of the Prostate: A Clinical Feasibility Study.

Prostate Cancer Clinical Trial

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- Molecular Studies and Clinical Correlations in Human Prostatic Disease.

Breast Cancer, or Prostate Cancer Clinical Trial

Centre Val d'Aurelle - Paul Lamarque - Recruiting 18 years to 80 years.
- Multicenter Prospective Evaluation of a Predictive Test of Late Toxicities After Radiotherapy by the Rate of Radiation Induced CD8 T-Lymphocyte Apoptosis: Application to Breast and Prostate Cancers..

Asian Chemo-na‹ve Patients With Metastatic Castrate-resistant Pro Clinical Trial using Tasquinimod; Placebo

Ipsen - Recruiting 20 years or older.
- A Phase III, Randomised, Double-Blind, Placebo-Controlled Study Of Tasquinimod In Asian Chemo-Na‹ve Patients With Metastatic Castrate-Resistant Prostate Cancer.
Tasquinimod; Placebo

Prostate Cancer, Hormone-resistant Prostate Cancer, Recurrent Pro Clinical Trial using laboratory biomarker analysis; questionnaire administration; doxorubicin-GnRH agonist conjugate AEZS-108

University of Southern California - Recruiting 18 years or older.
- A Phase I/II Trial of AN-152 [AEZS-108) in Castration- and Taxane-Resistant Prostate Cancer.
laboratory biomarker analysis; questionnaire administration; doxorubicin-GnRH agonist conjugate AEZS-108

Metastatic Prostate Cancer Clinical Trial using cabacitaxel

Tampere University Hospital - Recruiting 18 years or older.
- Open, Single-arm, Multicenter, Phase II Trial Investigating the Safety of Biweekly Cabazitaxel in Metastatic Castration Resistant Prostate Cancer Patients Previously Treated With a Docetaxel-containing Regimen.
cabacitaxel

Carcinoma Clinical Trial

Onkovis GmbH - Recruiting N/A or older.
- Open, Multicenter Observational Study of Docetaxel Utilized in Mono- or Combination Therapy for Treatment of Breast Cancer, NSCLC, Prostate Carcinoma, Adenocarcinoma of Stomach and Advanced Squamous Cell Carcinoma of Head/Neck Region..

Prostate Cancer Clinical Trial using Mitotane

University Health Network, Toronto - Recruiting 18 years or older.
- A Safety and Feasibility Study of Mitotane in Prostate Cancer.
Mitotane

Diarrhea, Hormone-resistant Prostate Cancer, Recurrent Prostate C Clinical Trial using cabazitaxel; prednisone; octreotide pamoate; questionnaire administration; octreotide acetate

University of Southern California - Recruiting 18 years or older.
- A Phase II Clinical Trial of Cabazitaxel Plus Prednisone With Octreotide in the Treatment of Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel.
cabazitaxel; prednisone; octreotide pamoate; questionnaire administration; octreotide acetate

Prostate Cancer Clinical Trial

AHS Cancer Control Alberta - Recruiting 18 years or older.
- Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences.

Prostate Cancer Clinical Trial using Sulforadex; alpha-cyclodextrin

Evgen Pharma - Recruiting 18 years to 45 years.
- A Randomised, Double-blind, Placebo-controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Pharmacodynamics of Sulforadexr in Healthy Male Subjects Following Daily Dosing for 7 Days.
Sulforadex; alpha-cyclodextrin

Androgen-independent Prostate Cancer Clinical Trial using Realisation of blood sample, urinary sample and tumor biopsy

Institut Paoli-Calmettes - Recruiting 18 years or older.
- Analysis of the Mechanisms of Actions of Hsp27 Responsible of the Androgen-independent Evolution in Prostate Cancer.
Realisation of blood sample, urinary sample and tumor biopsy

Prostate Cancer Clinical Trial using Docetaxel, Reolysin and Prednisone; Docetaxel and Prednisone

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Randomized Phase II Study of Reolysin in Combination With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Patients With Metastatic Castration Resistant Prostate Cancer.
Docetaxel, Reolysin and Prednisone; Docetaxel and Prednisone

Obesity, or Prostate Cancer Clinical Trial using Weight Loss; No Weight Loss Group

Department of Veterans Affairs - Recruiting N/A or older.
- Effect of Weight Loss on Prostate Cancer Pathology.
Weight Loss; No Weight Loss Group

Prostate Cancer Clinical Trial using CABAZITAXEL (XRP6258); Prednisone; Ciprofloxacin; G-CSF (Granulocyte colony-stimulating factor)

Sanofi - Recruiting 18 years or older.
- A Phase IV, Multicenter, National, Non-comparative, Open-label Study of Cabazitaxel, Combined With Prednisone and Prophylaxis of Neutropenia Complications in the Second-line Treatment of Patients With Metastatic Castration-resistant Prostate Cancer and After Failure of Docetaxel-based Chemotherapy. Descriptive Assessment of the Circulating Tumor Cells in This Context..
CABAZITAXEL (XRP6258); Prednisone; Ciprofloxacin; G-CSF (Granulocyte colony-stimulating factor)

Clinically Localized Prostate Cancer Clinical Trial using Stereotactic Body Radiation Therapy (SBRT)

Georgetown University - Recruiting 18 years or older.
- Quality of Life in Patients With Clinically Localized Prostate Cancer Treated With Stereotactic Body Radiation Therapy (SBRT).
Stereotactic Body Radiation Therapy (SBRT)

Bone Metastases, or Castration-Resistant Prostate Cancer Clinical Trial using Alpharadinr (Radium-223 dichloride) + docetaxel; Docetaxel

Algeta ASA - Recruiting 18 years or older.
- A Phase I/IIa Study of Safety and Efficacy of Alpharadinr With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer.
Alpharadinr (Radium-223 dichloride) + docetaxel; Docetaxel

Metastatic Castration-resistant Prostate Cancer Clinical Trial using Taxotere; Jevtana

Gustave Roussy, Cancer Campus, Grand Paris - Recruiting 18 years or older.
- A Study of Patient Preference Between Cabazitaxel and Docetaxel in First-line Chemotherapy for Metastatic Castrate-resistant Prostate Cancer.
Taxotere; Jevtana

Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Pro Clinical Trial using stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

City of Hope Medical Center - Recruiting 19 years or older.
- Stereotactic Body Radiation Therapy to the Prostate Fossa: Phase I Dose Escalation Study.
stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Prostate Cancer Clinical Trial using Supervised 1:1 exercise; Supervised group exercise; Home-based exercise

University Health Network, Toronto - Recruiting N/A or older.
- A Pilot RCT and Economic Analysis of Three Exercise Delivery Methods in Men With Prostate Cancer on ADT.
Supervised 1:1 exercise; Supervised group exercise; Home-based exercise

Prostatic Neoplasms Clinical Trial using CFG920

Novartis - Recruiting 18 years or older.
- A Phase I/II, Multicenter, Open-label Dose Finding Study of Oral CFG920 in Patients With Metastatic Castration-resistant Prostate Cancer.
CFG920

Prostate Cancer, or Radiation Toxicity Clinical Trial using medical chart review; questionnaire administration; quality-of-life assessment; brachytherapy; radiation therapy

University of California, San Francisco - Recruiting N/A or older.
- Pre-Operative Gleason Score and PSA and Clinical Stage in Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer.
medical chart review; questionnaire administration; quality-of-life assessment; brachytherapy; radiation therapy

Prostate Cancer Clinical Trial using Orteronel; Bicalutamide

European Organisation for Research and Treatment of Cancer - EORTC - Recruiting 18 years or older.
- Phase II Randomized Comparative Trial of TAK-700 (Orteronel) Versus Bicalutamide in Metastatic Prostate Cancer Patients Failing 1st Line Treatment With LHRH Agonists or Surgical Castration..
Orteronel; Bicalutamide

Castration-Resistant Prostate Cancer Clinical Trial

Dendreon - Recruiting 18 years or older.
- A Study to Evaluate Characteristics Predictive of a Positive Imaging Study for Distant Metastases in Patients With Castration-Resistant Prostate Cancer.

Prostate Cancer Clinical Trial using Fluorocholine (18F-FCH) Injection; PET scan; Whole body MRI

University Health Network, Toronto - Recruiting 18 years or older.
- 18F-FCH-PET/MR in Staging of High-Risk Prostate Cancer: A Multiparametric Approach.
Fluorocholine (18F-FCH) Injection; PET scan; Whole body MRI

Prostate Cancer Clinical Trial using Purified isoflavones; Methyl cellulose blend

H. Lee Moffitt Cancer Center and Research Institute - Recruiting 30 years to 80 years.
- Phase II Clinical Trial of Purified Isoflavones in Prostate Cancer: Comparing Safety, Effectiveness and Mechanism of Action Between African American and Caucasian Men.
Purified isoflavones; Methyl cellulose blend

Prostate Cancer Clinical Trial using APC-100

Adamis Pharmaceuticals Corporation - Recruiting 18 years or older.
- Phase 1/2a, Open-Label, Dose-Escalation and Safety Study of APC-100 [Pentamethylchromanol, 2,2,5,7,8-Pentamethyl-6] in Men With Advanced Prostate Cancer.
APC-100

Prostate Cancer Clinical Trial using Degarelix; Goserelin

Ferring Pharmaceuticals - Recruiting 18 years or older.
- An Open-label, Multi-centre, Randomised, Parallel-group Trial, Comparing Efficacy and Safety of Degarelix One-month Dosing Regimen With Goserelin in Chinese Patients With Prostate Cancer Requiring Androgen Ablation Therapy.
Degarelix; Goserelin

Prostate Cancer Clinical Trial using PET/CT; PET/MRI

New York University School of Medicine - Recruiting 18 years or older.
- Multimodality Imaging Assessment of Sipuleucel T Treatment and in Vivo Immune Response of Metastatic Castration Resistant Prostate Cancer Patients.
PET/CT; PET/MRI

Prostate Cancer Clinical Trial using Prohibitin-TP01

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A First-in-Man, Phase I Evaluation of A Single Cycle of Prohibitin Targeting Peptide 1 in Patients With Castrate-Resistant Prostate Cancer and No Standard Treatment Options.
Prohibitin-TP01

Lymphoceles, or Prostate Cancer Clinical Trial using Intuitive Vessel Sealer

OhioHealth - Recruiting 18 years or older.
- A Pilot Clinical Trial for the Prevention of Lymphoceles After Robotic Pelvic Lymph Node Dissections for Prostate Malignancies Using the da Vincir EndoWristr OneT Vessel Sealer.
Intuitive Vessel Sealer

Metastatic Prostate Cancer Clinical Trial using sipuleucel-T; enzalutamide

Dendreon - Recruiting 18 years or older.
- A Randomized, Open-label, Phase 2 Study of Sipuleucel-T With Concurrent Versus Sequential Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer.
sipuleucel-T; enzalutamide

Prostate Cancer Clinical Trial using Degarelix; Casodex; LHRH Agonist

University Health Network, Toronto - Recruiting 18 years to 75 years.
- Phase II Randomized Open Label Study of Neo-Adjuvant Degarelix vs. LHRH Agonist in Prostate Cancer Patients Prior to Radical Prostatectomy.
Degarelix; Casodex; LHRH Agonist

Metastatic Castration Sensitive Prostate Cancer Clinical Trial using Degarelix; Ipilimumab; Radical Prostatectomy

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase 2 Study Combining Ipilimumab and Degarelix With Radical Prostatectomy in Men With Newly Diagnosed Metastatic Castration Sensitive Prostate Cancer.
Degarelix; Ipilimumab; Radical Prostatectomy

Breast Cancer, Prostate Cancer, Lung Cancer, Lymphoma Cancer, or Clinical Trial using group intervention and questionnaires; individual phone intervention and questionnaires

Memorial Sloan-Kettering Cancer Center - Recruiting 70 years or older.
- Pilot of a Geriatric Group Psychoeducational Intervention for Elderly Patients With Cancer.
group intervention and questionnaires; individual phone intervention and questionnaires

Prostate Cancer, Salivary Gland Cancer, Endometrial Cancer, Squam Clinical Trial using OPB-111001

Otsuka Novel Products GmbH - Recruiting 18 years or older.
- A Two-part Phase 1/2a, Open-label, Dose Escalation Study to Evaluate the Tolerability and Preliminary Antitumour Activity of OPB-111001 in Patients With Advanced Cancers That Are Poorly Responsive to Standard Anticancer Treatment.
OPB-111001

Prostate Cancer Clinical Trial using Healthy bones pamphlet

University Health Network, Toronto - Recruiting 50 years or older.
- A Phase II RCT of Strategies to Improve Bone Health in Men on ADT.
Healthy bones pamphlet

Head and Neck Cancer, or Prostate Cancer Clinical Trial using MRI scanner with sequence

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers.
MRI scanner with sequence

Prostate Cancer Clinical Trial using questionnaire administration; quality-of-life assessment; image-guided radiation therapy; intensity-modulated radiation therapy; radiation therapy treatment planning/simulation

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting 18 years or older.
- A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0M0 Prostate Cancer.
questionnaire administration; quality-of-life assessment; image-guided radiation therapy; intensity-modulated radiation therapy; radiation therapy treatment planning/simulation

Prostate Cancer Clinical Trial using Enzalutamide; Abiraterone; Placebo for Enzalutamide; Prednisone

Medivation, Inc. - Recruiting 18 years or older.
- A Phase 4, Randomized, Double-Blind, Placebo-Controlled Study of Continued Enzalutamide Treatment Beyond Progression in Patients With Chemotherapy-Na‹ve Metastatic Castration-Resistant Prostate Cancer.
Enzalutamide; Abiraterone; Placebo for Enzalutamide; Prednisone

Prostate Cancer Clinical Trial

Yonsei University - Recruiting 20 years to 85 years.
- .

Prostate Cancer Clinical Trial using Hypofractionated Proton Therapy

Provision Center for Proton Therapy - Recruiting 18 years or older.
- A Phase II Study of Hypofractionated Image Guided Proton Therapy for Low and Intermediate Risk Prostate Cancer.
Hypofractionated Proton Therapy

Prostate Cancer Clinical Trial using Cancer Macrobead placement in abdominal cavity

The Rogosin Institute - Recruiting 18 years or older.
- An Open-Label, Phase 2 Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Cell-Containing Agarose- Agarose Macrobeads in the Treatment of Patients With Castration-Resistant Prostate Cancer Resistant to Docetaxel.
Cancer Macrobead placement in abdominal cavity

Cervical Cancer, or Prostate Cancer Clinical Trial using Hyperthermia; HDR brachytherapy

University of California, San Francisco - Recruiting 18 years or older.
- Pilot Study of a Catheter-based Ultrasound Hyperthermia System.
Hyperthermia; HDR brachytherapy

Prostate Cancer Clinical Trial using Flutamide; Sargramostim; recombinant fowlpox-prostate apecific antigen vaccine; recombinant vaccinia prostate specific antigen vaccine

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- A Randomized Phase II Trial Combining Vaccine Therapy With PROSTVAC/TRICOM and Flutamide vs. Flutamide Alone in Men With Androgen Insensitive, Non-Metastatic (D0.5) Prostate Cancer.
Flutamide; Sargramostim; recombinant fowlpox-prostate apecific antigen vaccine; recombinant vaccinia prostate specific antigen vaccine

Prostate Cancer, or Prostatic Neoplasms Clinical Trial using Visualase Thermal Therapy System

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- MR Image Guided Focal Therapy in Prostate Cancer.
Visualase Thermal Therapy System

Prostate Cancer Clinical Trial using Decipher Questionnaire

GenomeDx Biosciences Corp - Recruiting N/A or older.
- ASSESSing the Impact of Decipher on Practice Decision Making in Prostate Cancer After Surgery.
Decipher Questionnaire

Prostate Cancer Clinical Trial using Cabozantinib; Abiraterone

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- A Dose Finding Clinical Trial of Cabozantinib (XL 184) Administered in Combination With Abiraterone in Castration Resistant Prostate Cancer.
Cabozantinib; Abiraterone

Prostate Cancer Patients Undergoing Radical Prostatectomy Clinical Trial using Prehabilitation (PREHAB)

University of Guelph-Humber - Recruiting 45 years to 85 years.
- A Multicentre, Pilot Randomized Controlled Trial to Examine the Effects of Prehabilitation on Functional Outcomes After Radical Prostatectomy.
Prehabilitation (PREHAB)

Prostate Cancer Metastatic Clinical Trial using Cabozantinib

University of Michigan Cancer Center - Recruiting 18 years or older.
- A Phase II Trial of Cabozantinib (XL184) in Patients With Castrate-Resistant Prostate Cancer Metastatic to Bone.
Cabozantinib

Prostate Cancer Clinical Trial using Post-operative Adaptive Radiation Therapy

University Health Network, Toronto - Recruiting 18 years or older.
- A Feasibility Study of Post-operative Adaptive Radiation Therapy for Localized Prostate Cancer.
Post-operative Adaptive Radiation Therapy

Prostate Cancer, Castration Resistant Prostate Cancer, or Prostat Clinical Trial using cabozantinib; abiraterone; prednisone

Exelixis - Recruiting 18 years or older.
- A Randomized Phase 2 Study of Cabozantinib (XL184) in Combination With Abiraterone in Chemotherapy Na‹ve Subjects With Bone-Metastatic Castration-Resistant Prostate Cancer.
cabozantinib; abiraterone; prednisone

Prostate Cancer Clinical Trial using Preference Based Decision Aid

University of Pennsylvania - Recruiting 45 years or older.
- Treatment Preference and Patient Centered Prostate Cancer Care.
Preference Based Decision Aid

Prostate Cancer Clinical Trial using IMRT to 45 Gy; prostate bed proton boost of 21.6 CGE; Proton (prostate bed) to 70.2 CGE; IMRT to 45 Gy; proton boost to prostate bed to 25.2 CGE; Proton to 66.6 CGE

University of Florida - Recruiting 18 years or older.
- Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy.
IMRT to 45 Gy; prostate bed proton boost of 21.6 CGE; Proton (prostate bed) to 70.2 CGE; IMRT to 45 Gy; proton boost to prostate bed to 25.2 CGE; Proton to 66.6 CGE

Prostate Cancer Clinical Trial using Abiraterone; Prednisone

Massachusetts General Hospital - Recruiting 18 years or older.
- Investigator-Initiated, Pilot Translational Study of Circulating Tumor Cells to Identify Predictive Factors of Response to Abiraterone Acetate in Men With Castration-Resistant Prostate Cancer.
Abiraterone; Prednisone

Prostate Cancer Clinical Trial using Prostate cancer radiotherapy using real-time tracking

Royal North Shore Hospital - Recruiting 35 years to 85 years.
- Phase I Feasibility Study of Prostate Cancer Radiotherapy Using Realtime Dynamic Multileaf Collimator Adaptation and Radiofrequency Tracking (Calypso).
Prostate cancer radiotherapy using real-time tracking

Prostate Cancer Clinical Trial using antiandrogen therapy; releasing hormone agonist therapy; DNA analysis; RNA analysis; comparative genomic hybridization; gene expression analysis; laboratory biomarker analysis; diffusion-weighted magnetic resonance imaging; magnetic resonance spectroscopic imaging

National Cancer Institute (NCI) - Recruiting N/A or older.
- A Study of Changes in the Prostate Following Androgen Deprivation to Investigate Therapy Response and Resistance in Clinical Prostate Cancer.
antiandrogen therapy; releasing hormone agonist therapy; DNA analysis; RNA analysis; comparative genomic hybridization; gene expression analysis; laboratory biomarker analysis; diffusion-weighted magnetic resonance imaging; magnetic resonance spectroscopic imaging

Castration Resistant Prostate Cancer Clinical Trial using SOM230

Novartis - Recruiting 18 years or older.
- Phase 1 Study to Evaluate Safety, and Preliminary Efficacy of Pasireotide LAR in Castration Resistant Prostate Cancer.
SOM230

Prostate Neoplasms Clinical Trial using Abiraterone acetate; Prednisone; ADT (androgen deprivation therapy); Placebo

Janssen Research & Development, LLC - Recruiting 18 years or older.
- A Randomized, Double-blind, Comparative Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Subjects With High-Risk, Metastatic Hormone-naive Prostate Cancer (mHNPC).
Abiraterone acetate; Prednisone; ADT (androgen deprivation therapy); Placebo

Prostate Cancer Clinical Trial using ARN-509; LHRH Agonist

Aragon Pharmaceuticals, Inc. - Recruiting 18 years or older.
- The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer.
ARN-509; LHRH Agonist

Prostate Cancer Clinical Trial using Magnetic Nanoparticle Injection

University College London Hospitals - Recruiting N/A or older.
- Magnetic Nanoparticle Thermoablation-Retention and Maintenance in the Prostate:A Phase 0 Study in Men.
Magnetic Nanoparticle Injection

Prostate Cancer Clinical Trial using Cabozantinib; Androgen Ablation Therapy

M.D. Anderson Cancer Center - Recruiting N/A or older.
- An Observational Study of XL-184 Cabozantinib and Androgen Ablation in Patients With Androgen-Dependent Metastatic Prostate Cancer.
Cabozantinib; Androgen Ablation Therapy

Oligometastatic Prostate Cancer Clinical Trial using SBRT/SHRT

University of Florida - Recruiting 18 years or older.
- Phase II Stereotactic Body Radiotherapy (SBRT) and Stereotactic Hypofractionated Radiotherapy (SHRT) for Oligometastatic Prostate Cancer.
SBRT/SHRT

Prostate Adenocarcinoma Clinical Trial using Stereotactic Ablative Radiation

Sunnybrook Health Sciences Centre - Recruiting 18 years or older.
- Two StereoTactic Ablative Adaptive Radiotherapy Treatments for Localized Prostate Cancer.
Stereotactic Ablative Radiation

Prostate Cancer Clinical Trial using Tivozanib; Enzalutamide

Massachusetts General Hospital - Recruiting 18 years or older.
- Phase 2 Combination Trial of Tivozanib and Enzalutamide in Men With Advanced Prostate Cancer.
Tivozanib; Enzalutamide

Prostate Cancer Clinical Trial

AbbVie - Recruiting 18 years or older.
- Canadian Real Life Evaluation of Exercise and Diet in Patients Treated With Lupronr for the Management of Prostate Cancer:(CRONOS II).

Nonmetastatic Castration-Resistant Prostate Cancer Clinical Trial using Enzalutamide; Placebo

Medivation, Inc. - Recruiting 18 years or older.
- A Multinational, Phase 3, Randomized, Double Blind, Placebo Controlled, Efficacy and Safety Study of Enzalutamide in Patients With Nonmetastatic Castration Resistant Prostate Cancer.
Enzalutamide; Placebo

Prostate Cancer Clinical Trial using Prostate HistoScanning

Advanced Medical Diagnostics s.a. - Recruiting 18 years or older.
- Diagnostic Performance of Prostate HistoScanningTM (PHS) in Men at Risk of Prostate Cancer Scheduled for an Initial Prostate Biopsy.
Prostate HistoScanning

Adenocarcinoma of Prostate, or Progression of Prostate Cancer Clinical Trial using Cabazitaxel; Pelvic radiotherapy; prostate radiotherapy

UNICANCER - Recruiting 18 years to 75 years.
- A Randomized Phase III, Factorial Design, of Cabazitaxel and Pelvic Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse.
Cabazitaxel; Pelvic radiotherapy; prostate radiotherapy

Prostate Cancer Clinical Trial using 18F-Fluoroazomycin Arabinoside (18F-FAZA)

University Health Network, Toronto - Recruiting 18 years or older.
- A Feasibility Study of Hypoxia Imaging in Patients With Prostate Cancer Using Positron Emission Tomography (PET) With 18F-Fluoroazomycin Arabinoside (18F-FAZA).
18F-Fluoroazomycin Arabinoside (18F-FAZA)

Patients With Prostate Cancer Clinical Trial using Volumetric Modulated Arc Therapy (VMAT) and High-Dose Rate (HDR) Radiotherapy; No Active Treatment - completed Prior Radiation

University Health Network, Toronto - Recruiting 18 years or older.
- Tumor Targeted Radiotherapy for Patients With Localized Prostate Cancer.
Volumetric Modulated Arc Therapy (VMAT) and High-Dose Rate (HDR) Radiotherapy; No Active Treatment - completed Prior Radiation

Prostate Cancer Clinical Trial using High Quality Volume CT Scan; MRI Scan

University Health Network, Toronto - Recruiting 18 years or older.
- Prostate Delineation During Radiation Treatment Planning for Prostate Cancer: Comparison of High Quality Volume Computerized Tomography With Conventional Tomography and Magnetic Resonance Imaging.
High Quality Volume CT Scan; MRI Scan

Prostate Cancer Clinical Trial using whole-mount sectioning of the prostate

University Health Network, Toronto - Recruiting 18 years or older.
- Salvage Prostatectomy After Radiotherapy: Whole-Mount Histopathological Validation for Tumor-Targeted Salvage HDR Brachytherapy.
whole-mount sectioning of the prostate

Prostate Cancer Patients Who Have Brachytherapy Seed Implant Clinical Trial using MRI Scan

University Health Network, Toronto - Recruiting 18 years or older.
- Identifying Prostate Brachytherapy Seeds Using MRI.
MRI Scan

Patients With Prostate Cancer Clinical Trial using MRI Guided Needles to deliver HDR Brachytherapy

University Health Network, Toronto - Recruiting 18 years or older.
- MRI-Guided HDR Brachytherapy for Prostate Cancer.
MRI Guided Needles to deliver HDR Brachytherapy

Prostate Cancer Clinical Trial using Immediate diet and exercise intervention; Delayed diet and exercise intervention

University of Alabama at Birmingham - Recruiting 19 years or older.
- Exploring the Impact of Negative Energy Balance in Men With Prostate Cancer.
Immediate diet and exercise intervention; Delayed diet and exercise intervention

Progression of Prostate Cancer Clinical Trial using Whole Body MRI; Focal Salvage Therapy; MRI Targeted biopsies

University College London Hospitals - Recruiting 18 years or older.
- An Evaluation of a Novel Imaging Based Complex Diagnostic and Therapeutic Pathway Intervention for Men Who Fail Radiotherapy for Prostate Cancer..
Whole Body MRI; Focal Salvage Therapy; MRI Targeted biopsies

Prostate Cancer Clinical Trial using 3-dimensional conformal radiation therapy (3D-CRT); intensity-modulated radiation therapy (IMRT); samarium Sm 153 lexidronam pentasodium

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- A Phase II Trial of Samarium 153 Followed by Salvage Prostatic Fossa 3D-CRT or IMRT Irradiation in High-Risk, Clinically Non-Metastatic Prostate Cancer After Radical Prostatectomy.
3-dimensional conformal radiation therapy (3D-CRT); intensity-modulated radiation therapy (IMRT); samarium Sm 153 lexidronam pentasodium

Pharmacogenetic Study Clinical Trial using Abiraterone Acetate

Centre Antoine Lacassagne - Recruiting 18 years to 90 years.
- Pharmacogenetic Study in Castration-resistant Prostate Cancer Patients Treated With Abiraterone Acetate.
Abiraterone Acetate

Lung Cancer, or Solid Tumor (Not Breast or Prostate Cancers) Clinical Trial using Cabozantinib

Massachusetts General Hospital - Recruiting 18 years or older.
- Phase II Trial of Cabozantinib (XL184) in Patients With Advanced Solid (Non-breast, Non-prostate) Malignancies and Bony Metastases.
Cabozantinib

PROSTATE CANCER Clinical Trial using Targeted biopsies of the prostate

University College London Hospitals - Recruiting 18 years or older.
- .
Targeted biopsies of the prostate

Perioperative/Postoperative Complications, or Prostate Cancer Clinical Trial using robot-assisted laparoscopic surgery; questionnaire administration; intraoperative complication management/prevention

City of Hope Medical Center - Recruiting 18 years or older.
- A Prospective Randomized Trial of Pelvic Drain Placement Versus no Pelvic Drain Placement After Robotic Assisted Laparoscopic Prostatectomy (RALP) in Patients With Prostate Cancer.
robot-assisted laparoscopic surgery; questionnaire administration; intraoperative complication management/prevention

Prostate Cancer Clinical Trial using Itraconazole

University of California, San Francisco - Recruiting 18 years or older.
- Hedgehog Inhibition as a Non-Castrating Approach to Hormone Sensitive Prostate Cancer: A Phase II Study of Itraconazole in Biochemical Relapse.
Itraconazole

Metastatic Breast Cancer, Colorectal Cancer, or Prostate Cancer Clinical Trial using Foxy-5

WntResearch AB - Recruiting 18 years or older.
- Phase I Dose Escalating Study to Evaluate the Safety, Tolerability, Anti-Tumour Activity and Pharmacokinetic and Pharmacodynamic Profiles of Foxy-5 in Patients With Metastatic Breast, Colorectal or Prostate Cancer.
Foxy-5

Prostate Cancer Clinical Trial using bicalutamide; flutamide; radiation therapy

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- A Phase III Trial of Short Term Androgen Deprivation With Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients With a Rising PSA After Radical Prostatectomy.
bicalutamide; flutamide; radiation therapy

Metastatic Castration- Resistant Prostate Cancer (mCRCP) Clinical Trial using Enzalutamide

Astellas Pharma Inc - Recruiting N/A or older.
- A Multicenter, Single-Arm, Open-Label, Post-Marketing Safety Study to Evaluate the Risk of Seizure Among Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated With Enzalutamide Who Are at Potential Increased Risk of Seizure.
Enzalutamide

Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment Clinical Trial using hypofractionated radiation therapy

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- A Randomized Phase II Trial of Hypofractionated Radiotherapy for Favorable Risk Prostate Cancer.
hypofractionated radiation therapy

Prostate Cancer Clinical Trial using High Intensity Focused Ultrasound

Jewish General Hospital - Recruiting 50 years or older.
- Focal Therapy Using High Intensity Focused Ultrasound (ABLATHERMr) for Localised Prostate Cancer.
High Intensity Focused Ultrasound

Castration Refractory Prostate Cancer, or CRPC Clinical Trial using VT-464 Dose Level 1: given orally twice daily in 28 day cycles; VT-464 Dose Level 2: given orally twice daily in 28 day cycles; VT-464 Dose Level 3: given orally twice daily in 28 day cycles

Viamet Pharmaceuticals, Inc. - Recruiting 18 years or older.
- A Phase 1/2 Open-Label, Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT-464 in Chemotherapy-Na‹ve Patients With Castration-Refractory Prostate Cancer.
VT-464 Dose Level 1: given orally twice daily in 28 day cycles; VT-464 Dose Level 2: given orally twice daily in 28 day cycles; VT-464 Dose Level 3: given orally twice daily in 28 day cycles

Distal Urethral Cancer, Metastatic Transitional Cell Cancer of th Clinical Trial using gemcitabine hydrochloride; cisplatin; placebo; bevacizumab; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma.
gemcitabine hydrochloride; cisplatin; placebo; bevacizumab; laboratory biomarker analysis

Metastatic Castration Resistant Prostate Cancer (CRPC) Clinical Trial using Hamsa-1T TL-118

Tiltan Pharma Ltd. - Recruiting 18 years or older.
- A Phase IIB Clinical Trial of the Anti-Angiogenic Drug Combination Hamsa-1T in Metastatic Castration Resistant Prostate Cancer (CRPC).
Hamsa-1T TL-118

Cancer, Cataract, Low Bone Mineral Density, Osteopenia, Osteoporo Clinical Trial using Denosumab; Placebo

Amgen - Recruiting 30 years or older.
- A Double-blind, Placebo-controlled Study to Evaluate New or Worsening Lens Opacifications in Subjects With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss Due to Androgen-Deprivation Therapy.
Denosumab; Placebo

Prostate Cancer Clinical Trial using focal salvage HDR prostate brachytherapy

Sunnybrook Health Sciences Centre - Recruiting 18 years or older.
- Pilot Study of Focal Salvage HDR Prostate Brachytherapy.
focal salvage HDR prostate brachytherapy

Prostate Cancer Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 40 years to 90 years.
- A Case-Control Study of Prostate Cancer in the Greater Baltimore Area: An Epidemiological Study of Genetic Risk Factors for Prostate Cancer in African-American and Caucasian Males.

Prostate Cancer Clinical Trial using Irreversible Electroporation

Clinical Research Office of the Endourological Society - Recruiting N/A or older.
- The Safety and Efficacy of Irreversible Electroporation for the Ablation of Prostate Cancer Assessed by Procedural Related Side Effects and Post Prostatectomy Histology: A Prospective Human In-Vivo Study..
Irreversible Electroporation

Prostate Cancer Clinical Trial using ADT Therapy; Axitinib; Prostatectomy

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Pre-surgical Androgen Deprivation Therapy With or Without Axitinib in Previously Untreated Prostate Cancer Patients With Known or Suspected LymphNode Metastasis.
ADT Therapy; Axitinib; Prostatectomy

Prostate Cancer Clinical Trial using Radiotherapy with IMRT and CyberKnife Boost

Georgetown University - Recruiting 18 years or older.
- Phase II Study to Evaluate the Efficacy of Intensity Modulated Radiation Therapy With Hypofractionated Radiosurgical Boosts in the Treatment of Clinically Localized Prostate Cancer.
Radiotherapy with IMRT and CyberKnife Boost

Prostate Cancer Clinical Trial using [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone

Memorial Sloan-Kettering Cancer Center - Recruiting N/A or older.
- [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer.
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone

Prostate Cancer Clinical Trial using GTx-758 125 mg; GTx-758 250 mg

GTx - Recruiting 18 years or older.
- Phase II, Open Label Study of the Effect of GTx-758 as Secondary Hormonal Therapy on Serum PSA and Serum Free Testosterone Levels in Men With Metastatic Castration Resistant Prostate Cancer Maintained on Androgen Deprivation Therapy.
GTx-758 125 mg; GTx-758 250 mg

Prostate Cancer Clinical Trial using Proton Beam Therapy; Questionnaire

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Phase II Trial of Hypofractionated Proton Beam Therapy in Men With Localized Prostate Adenocarcinoma.
Proton Beam Therapy; Questionnaire

Prostate Cancer Clinical Trial using ASP3550; Goserelin

Astellas Pharma Inc - Recruiting 20 years or older.
- ASP3550 Phase III Study - An Open-Label, Active-Controlled, Parallel-Arm Study, Comparing ASP3550 With Goserelin Acetate in Patients With Prostate Cancer -.
ASP3550; Goserelin

Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Pro Clinical Trial using Akt inhibitor MK2206; bicalutamide; clinical observation

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Androgen Receptor Modulation Phase II, Randomized Study of MK-2206 - Bicalutamide Combination in Patients With Rising PSA at High-Risk of Progression After Primary Therapy.
Akt inhibitor MK2206; bicalutamide; clinical observation

Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage II Clinical Trial using cholecalciferol; genistein; placebo; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase IIA, Randomized Placebo-Controlled Trial of Single High Dose Cholecalciferol and Daily Genistein (G-2535) Versus Placebo in Men With Early Stage Prostate Cancer Undergoing Prostatectomy.
cholecalciferol; genistein; placebo; laboratory biomarker analysis; pharmacological study

Breast Cancer, Prostate Cancer, or Colorectal Cancer Clinical Trial

Viatar LLC - Recruiting 18 years or older.
- Collection of Blood Specimens for Circulating Tumor Cell Analysis.

Prostate Cancer, Erectile Dysfunction Following Radical Prostatec Clinical Trial using Intensive Fitness Intervention; TRIMM

Johns Hopkins University - Recruiting 40 years to 65 years.
- Health Interventions in Men Undergoing Radical Prostatectomy- A Randomized Controlled Clinical Trial.
Intensive Fitness Intervention; TRIMM

Prostate Cancer Clinical Trial using Cabazitaxel; Intensity Modulated Radiation Therapy (IMRT); Anti-Androgen Therapy: Bicalutamide; Luteinizing Hormone-Releasing Hormone (LHRH) Agonist

Thomas Jefferson University - Recruiting 18 years or older.
- Phase I Trial of Weekly Cabazitaxel With Concurrent Intensity Modulated Radiation Therapy and Androgen Deprivation Therapy for the Treatment of Locally Advanced High Risk Adenocarcinoma of the Prostate.
Cabazitaxel; Intensity Modulated Radiation Therapy (IMRT); Anti-Androgen Therapy: Bicalutamide; Luteinizing Hormone-Releasing Hormone (LHRH) Agonist

Prostate Cancer, or Sexual Dysfunction Clinical Trial using laboratory biomarker analysis; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- HIFU Lesion Control in Patients With Non-metastatic Progressive Prostate Cancer.
laboratory biomarker analysis; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

Prostate Cancer Clinical Trial using gonadotrophin releasing hormone; cyproterone acetate; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A to 79 years.
- Intermittent Hormone Therapy for Newly Diagnosed Metastatic Prostate Cancer.
gonadotrophin releasing hormone; cyproterone acetate; quality-of-life assessment

Prostate Cancer Clinical Trial using pharmacological study; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- An Evaluation of Lesion Control Using Focal Ablation With High Intensity Focused Ultrasound in the Treatment of Non-Metastatic Progressive Prostate Cancer.
pharmacological study; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

Patients Scheduled for Prostate Biopsy Because of Increased Serum Clinical Trial using urinary PCA3 test using Progensar PCA3 assay kit (Gen-Probe)

Hospices Civils de Lyon - Recruiting 18 Months or older.
- Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis.
urinary PCA3 test using Progensar PCA3 assay kit (Gen-Probe)

Prostate Cancer, or Radiation Therapy Clinical Trial using Curcumin; Placebo

Shahid Beheshti Medical University - Recruiting 50 years to 80 years.
- Radiation Therapy With or Without Curcumin Supplement in Treating Patients With Prostate Cancer.
Curcumin; Placebo

Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage Clinical Trial using stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- High-Dose Stereotactic Body Radiation Therapy in Treating Patients With Low-, Intermediate-, or High-Risk Localized Prostate Cancer.
stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Prostate Cancer Clinical Trial using Degarelix

British Columbia Cancer Agency - Recruiting 40 years to 80 years.
- Phase II Trial Assessing the Feasibility and Toxicity of Degarelix in Achieving Prostate Downsizing Prior to Treatment With Permanent Seed Prostate Brachytherapy.
Degarelix

Prostate Cancer Clinical Trial using CyberKnife Boost

Boston Medical Center - Recruiting 18 years or older.
- Phase II Study of Hypofractionated Stereotactic Body Radiation Therapy as a Boost to the Prostate for Treatment of Localized, Non-Metastatic, High Risk Prostate Cancer.
CyberKnife Boost

Breast Cancer, Lung Cancer, Metastatic Cancer, Multiple Myeloma, Clinical Trial using assessment of therapy complications

Southwest Oncology Group - Recruiting N/A or older.
- S0702: A Prospective Observational Multicenter Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients With Bone Metastases Starting Zoledronic Acid Treatment.
assessment of therapy complications

Prostate Cancer Clinical Trial using exercise intervention; nutritional supplementation; quality-of-life assessment; questionnaire administration; pharmacological study; laboratory biomarker analysis

USC/Norris Comprehensive Cancer Center - Recruiting 50 years or older.
- Exercise and Whey Protein Supplementation as Adjunctive Therapy for Patients With Prostate Cancer Receiving Androgen Deprivation Therapy.
exercise intervention; nutritional supplementation; quality-of-life assessment; questionnaire administration; pharmacological study; laboratory biomarker analysis

Prostate Cancer Clinical Trial using hypofractionation

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate.
hypofractionation

Prostate Cancer Clinical Trial using hypofractionated helical IMRT

University of Heidelberg - Recruiting 18 years to 80 years.
- Hypofractionated Helical Intensity-Modulated Radiotherapy of the Prostate Bed After Prostatectomy With or Without the Pelvic Lymph Nodes - the PRIAMOS Trial.
hypofractionated helical IMRT

Adenocarcinoma of the Prostate Clinical Trial using Radiation Therapy; Androgen Deprivation Therapy (ADT)

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- Stereotactic Body Radiation Therapy and Short-Term Androgen Ablation for Intermediate-Risk, Localized, Adenocarcinoma of the Prostate.
Radiation Therapy; Androgen Deprivation Therapy (ADT)

Prostate Cancer, Benign Prostatic Hyperplasia, or Enlarged Prosta Clinical Trial using BOTOX

The University of Texas Health Science Center, Houston - Recruiting 50 years or older.
- H-25362: Effect of Botulinum Neurotoxin Type A Prostate Injections on Neurogenesis and Gene Profile Expression in Men With Localized Prostate Cancer and Lower Urinary Tract Symptoms/BPH (Protocol # 05-09-30-03).
BOTOX

Prostate Cancer Clinical Trial using 177Lu-J591; Ketoconazole; Hydrocortisone; 111In-J591

Weill Medical College of Cornell University - Recruiting 18 years or older.
- A Randomized Phase 2 Trial of 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With High-Risk Castrate Biochemically Relapsed Prostate Cancer After Local Therapy.
177Lu-J591; Ketoconazole; Hydrocortisone; 111In-J591

Prostate Cancer Clinical Trial using Cabozantinib

Cedars-Sinai Medical Center - Recruiting 18 years or older.
- A Phase II Study of Cabozantinib (XL184) Therapy in Castrate Resistant Prostate Cancer (CRPC) With Visceral Metastases.
Cabozantinib

Melanoma, Castrate Resistant Prostate Cancer, or Renal Cancer Clinical Trial using Naltrexone

Brown University - Recruiting 18 years or older.
- Low Dose Naltrexone for Metastatic Melanoma, Castrate Resistant Prostate Cancer and Renal Cancer: A Phase II Brown University Oncology Group Research Project.
Naltrexone

Prostate Cancer Clinical Trial using questionnaires

University of Erlangen-Nrnberg Medical School - Recruiting 18 years or older.
- Evaluation of Socioeconomic Aspects Before and After Primary Radiation Therapy (Percutaneous or Interstitial or Combined Percutaneous and Interstitial) in Patients With Prostate Cancer.
questionnaires

Prostate Cancer, or Castrate Resistant Prostate Cancer Clinical Trial using sipuleucel-T; ipilimumab

Prostate Oncology Specialists, Inc. - Recruiting 18 years or older.
- Phase 1 Study of Sipuleucel-T and Ipilimumab in Combination for Advanced Prostate Cancer.
sipuleucel-T; ipilimumab

Prostatic Cancer Clinical Trial using Hyaluronic acid

Ume† University - Recruiting 18 years to 75 years.
- Initiating Phase II-III Study to Evaluate the Technique and Effects of Separating the Prostate From the Rectum With Hyaluronic Acid During Radiotherapy.
Hyaluronic acid

Metastatic Castration Resistant Prostate Cancer Patients Clinical Trial using metastasis biopsy

Gustave Roussy, Cancer Campus, Grand Paris - Recruiting 18 years or older.
- Prostate Cancer Evaluation of TaRgets in Genito Urinary Screening Program.
metastasis biopsy

Prostate Cancer Clinical Trial using Goldlock; Visicoil smallest size; Visicoil larger size; Bard goldmarker smallest size; Bard goldmarker larger size

University Hospital, Ghent - Recruiting 18 years or older.
- The Implantation Under Echography of Fiducial Markers in the Intraprostatic Lesion and Prostate.
Goldlock; Visicoil smallest size; Visicoil larger size; Bard goldmarker smallest size; Bard goldmarker larger size

Prostate Cancer Clinical Trial using Pantoprazole

University Health Network, Toronto - Recruiting 18 years or older.
- Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate Cancer - a Single Arm Phase II Clinical Trial With a Predefined Reference Group (PANDORA).
Pantoprazole

Prostate Cancer Clinical Trial using Choline-PET

Bangalore Institute of Oncology - Recruiting N/A or older.
- Evaluation of the Incidence of Choline-PET Detected Nodal Metastases Among Newly Diagnosed Prostate Cancer Patients With Presumed Absence of Nodal and Distant Metastases..
Choline-PET

Prostate Cancer Clinical Trial using bicalutamide; goserelin acetate; clinical observation

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Intermittent Androgen Deprivation in Patients With Stage D2 Prostate Cancer, Phase III.
bicalutamide; goserelin acetate; clinical observation

Prostate Cancer Clinical Trial using ExAblate MRgFUS for prostate cancer

InSightec - Recruiting N/A to 75 years.
- Safety, Compatibility and Imaging Quality of ExAblate Prostate Applicator for Prostate Cancer.
ExAblate MRgFUS for prostate cancer

Prostate Cancer Clinical Trial using performance of PET/CT and whole-body MRI

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Role of PET/CT With Fluorine-18 Tracers and of Diffusion Weighted Whole-body MRI in the Early Detection of Bone Metastases in Prostate Cancer.
performance of PET/CT and whole-body MRI

Prostatic Neoplasms, Cancer of Prostate, Prostate Cancer, or Pros Clinical Trial using Laparoscopic Radical Prostatectomy (without a simulator); Laparoscopic Radical Prostatectomy (with a simulator)

Assistance Publique - H“pitaux de Paris - Recruiting N/A or older.
- A Prospective Randomized Study to Evaluate the Clinical Impact of a Laparoscopic Radical Prostatectomy Online Simulator.
Laparoscopic Radical Prostatectomy (without a simulator); Laparoscopic Radical Prostatectomy (with a simulator)

Prostate Cancer Clinical Trial

University of Lausanne Hospitals - Recruiting N/A to 80 years.
- Impact of F-18-Fluorocholine PET/CT and MR Imaging/ Spectroscopy in the Management of Primary and Recurrent Prostate Cancer.

Prostate Cancer Clinical Trial using MRI assisted TRUS guided biopsy

Canadian Urology Research Consortium - Recruiting 18 years or older.
- Active Surveillance Magnetic Resonance Imaging Study.
MRI assisted TRUS guided biopsy

Locally Advanced Prostate Cancer Clinical Trial using TNFeradeT Biologic

GenVec - Recruiting N/A or older.
- A PHASE I SAFETY AND TOLERABILITY TRIAL OF RADIOTHERAPY, ANDROGEN DEPRIVATION, AND INTRATUMORAL INJECTIONS OF AdGVEGR.TNF.11D (TNFeradeTM) FOR PATIENTS WITH LOCALLY ADVANCED PROSTATE CANCER.
TNFeradeT Biologic

Prostate Cancer Clinical Trial using Prostate HistoScanning; Multi-parametric MRI; Transperineal prostate mapping biopsy; Image guided biopsies

University College London Hospitals - Recruiting 20 years or older.
- PICTURE - Prostate Imaging (Multi-parametric MRI and Prostate HistoScanningT) Compared to Transperineal Ultrasound Guided Biopsy for Significant Prostate Cancer Risk Evaluation..
Prostate HistoScanning; Multi-parametric MRI; Transperineal prostate mapping biopsy; Image guided biopsies

Prostate Cancer Clinical Trial using sildenafil 100mg

Seoul National University Bundang Hospital - Recruiting N/A or older.
- Early Start of Oral Sildenafil 100mg for Erectile Dysfunction After Robotic Assisted Laparoscopic Radical Prostatectomy.
sildenafil 100mg

Prostate Cancer Clinical Trial

Toowoomba Regional Cancer Research Centre - Recruiting N/A or older.
- A Phase 2 Clinical Trial Exploring 3-Dimensional Imaging of Androgen Deprivation Induced Osteoporosis, Radiotherapy Hypofractionation and the Prognostic Significance of Micrometastatic Disease in Men With Prostate Cancer.

Prostate Cancer Clinical Trial using Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine

Biotech Equity Partners Pty Ltd - Recruiting 18 years or older.
- A Phase I, Open-label, Dose Escalation Study to Assess the Safety and Tolerability of FP253 in Combination With Fludarabine Phosphate.
Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine

Prostate Cancer Clinical Trial using cyproterone acetate; releasing hormone agonist therapy; hypofractionated radiation therapy; intensity-modulated radiation therapy

National Cancer Institute (NCI) - Recruiting N/A or older.
- Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer: CHHIP.
cyproterone acetate; releasing hormone agonist therapy; hypofractionated radiation therapy; intensity-modulated radiation therapy

Prostate Cancer Clinical Trial

Sir Mortimer B. Davis - Jewish General Hospital - Recruiting N/A or older.
- A Prospective Study Assessing the Predictive Value of TMPRSS2-ERG Gene Fusion and PTEN Deletion in High Risk Prostate Cancer Patients.

Prostate Cancer, Cervical Cancer, or Anal Canal Cancers Clinical Trial using Intensity-Modulated Radiation Therapy

Centre Ren‚ Gauducheau - Recruiting 18 years or older.
- Medico-economic Evaluation Comparing Conformal Radiotherapy With Intensity Modulation (IMRT) Performed by, Helical Tomotherapy (Hi Art) and Dynamic Arc Therapy (RapidArc, VMAT) in Cancers With Pelvic Lymph Node Irradiation (Prostate, Cervix, Anal Canal).
Intensity-Modulated Radiation Therapy

Prostate Cancer Clinical Trial using flutamide; triptorelin; neoadjuvant therapy; radiation therapy

National Cancer Institute (NCI) - Recruiting N/A to 74 years.
- Multicentre Randomized Trial Assessing the Efficacy of a Short Neoadjuvant and Concomitant Hormone Therapy to an Exclusive Curative Cornformational Radiotherapy of Locolized Prostate Cancer With Intermediate Prognosis.
flutamide; triptorelin; neoadjuvant therapy; radiation therapy

Prostate Cancer Clinical Trial using counseling intervention; educational intervention; quality-of-life assessment; therapeutic conventional surgery; iodine I 125; palladium Pd 103

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Surgery and Brachytherapy: A Randomized Evaluation. Randomized Controlled Trial of Brachytherapy Versus Radical Prostatectomy in Good Risk Prostate Cancer: A Feasibility Study.
counseling intervention; educational intervention; quality-of-life assessment; therapeutic conventional surgery; iodine I 125; palladium Pd 103

Prostate Cancer Clinical Trial using goserelin acetate; adjuvant therapy; radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase III Randomized Study of Adjuvant Radiotherapy With Versus Without Concurrent Goserelin in Patients Who Have Undergone Surgery for Recurrent or Refractory Prostate Cancer.
goserelin acetate; adjuvant therapy; radiation therapy

Prostate Cancer Clinical Trial using Flutamide; Leuprolide Acetate

University of Washington - Recruiting 21 years or older.
- A Prospective Study of Intermittent Androgen Suppression in Men With Localized Prostate Cancer Who Have Biochemical Relapse After Radiation Therapy or Radical Prostatectomy.
Flutamide; Leuprolide Acetate

Breast Cancer, Depression, Long-term Effects of Cancer Treatment, Clinical Trial using educational intervention; informational intervention; internet-based intervention; questionnaire administration; study of socioeconomic and demographic variables; survey administration; psychosocial assessment and care; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- Cancer Information Service Research Consortium: Years 2006-2011 Program Narrative and Overview.
educational intervention; informational intervention; internet-based intervention; questionnaire administration; study of socioeconomic and demographic variables; survey administration; psychosocial assessment and care; quality-of-life assessment

Bladder Cancer, or Prostate Cancer Clinical Trial using Multiphoton microscopy

Weill Medical College of Cornell University - Recruiting 21 years to 85 years.
- Use of Multiphoton Microscopy in the Diagnosis of Cancer.
Multiphoton microscopy

Previous Negative Biopsy Clinical Trial using Robotic Transperineal Biopsy

Singapore General Hospital - Recruiting N/A or older.
- Study of Prostate Cancer Detection With in House Developed Robot.
Robotic Transperineal Biopsy

Prostate Cancer Clinical Trial

National Taiwan University Hospital - Recruiting 35 years to 90 years.
- The Effectiveness of 18F-fluorocholine PET in Detecting, Staging and Following-up Prostate Cancer.

Prostate Cancer, or Psychosocial Effects of Cancer and Its Treatm Clinical Trial using questionnaire administration; survey administration; psychosocial assessment and care

National Cancer Institute (NCI) - Recruiting 18 years or older.
- PROSTATE CANCER SYMPTOM MANAGEMENT FOR LOW LITERACY MEN.
questionnaire administration; survey administration; psychosocial assessment and care

Prostate Cancer Clinical Trial using docetaxel; sorafenib tosylate

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Study of Sorafenib in Combination With Docetaxel in Patients With Androgen-Independent Prostate Cancer.
docetaxel; sorafenib tosylate

Prostate Cancer Clinical Trial using High Intensity Focused Ultrasound

Lawson Health Research Institute - Recruiting 40 years to 80 years.
- Feasibility Study for Locally Recurrent Prostate Cancer Treatment Following Radiation Failure With High Intensity Focused Ultrasound (HIFU).
High Intensity Focused Ultrasound

Prostate Cancer Clinical Trial using Telephone Interpersonal Counselling Intervention; Telephone delivered education only

University of Arizona - Recruiting 21 years or older.
- .
Telephone Interpersonal Counselling Intervention; Telephone delivered education only

Prostate Cancer Clinical Trial using Endomicroscopy

Optiscan Pty Ltd - Recruiting 18 years or older.
- In Vivo Confocal Endomicroscopy During da Vinci Robot Assisted Prostatectomy: Feasibility Study.
Endomicroscopy

Prostatic Neoplasms Clinical Trial using Samarium Sm-153 lexidronam + Docetaxel

Cytogen Corporation - Recruiting N/A or older.
- Phase I/II Trial of Samarium Sm-153 Lexidronam Combined With Docetaxel for Patients With Androgen-Independent Prostate Cancer.
Samarium Sm-153 lexidronam + Docetaxel

Obesity, or Prostate Cancer Clinical Trial using Bariatric Surgery

Maimonides Medical Center - Recruiting 20 years to 60 years.
- Effect of Lap-Band Induced Weight Loss on Serum PSA Levels, Testosterone, Estrogen and Other Serum Markers.
Bariatric Surgery

Metastatic Prostate Cancer Clinical Trial using 177Lu-CYT-500

Cytogen Corporation - Recruiting 18 years or older.
- A Phase 1 Study of Radiolabeled Monoclonal Antibody 7E11-C5.3(177Lu-meO-DOTA-7E11;CYT-500) in Patients With Progressive Androgen-Independent Prostate Cancer.
177Lu-CYT-500

Breast Cancer, Prostate Cancer, Vertebral Metastasis, or Pain Clinical Trial using Vertebroplasty

McGill University Health Center - Recruiting 35 years to 75 years.
- Challenging the Paradigm in Pain Relief for Advanced Breast and Prostate Cancer Patients With Vertebral Metastasis: Vertebral Augmentation With Cement Plus Radiotherapy Versus Radiotherapy. A Randomized, Prospective, Double Blind Pilot Study.
Vertebroplasty

Prostate Cancer Clinical Trial using Taxotere; Celecoxib

Department of Veterans Affairs, New Jersey - Recruiting 18 years or older.
- A Phase II Trial of Combination Therapy With Celecoxib and Taxotere for the Treatment of Stage D3 Prostate Cancer.
Taxotere; Celecoxib

Prostate Cancer Clinical Trial using Epirubicin; Estramustine Phosphate; Celecoxib

Department of Veterans Affairs, New Jersey - Recruiting 18 years or older.
- A Phase II Trial of Epirubicin With Estramustine Phosphate and Celecoxib for the Treatment of Hormone Resistant Prostate Cancer (HRPC).
Epirubicin; Estramustine Phosphate; Celecoxib