86 results found.

Chronic Obstructive Pulmonary Disease Clinical Trial using Inspiratory muscle training

University Hospital, Brest - Recruiting 18 years or older.
- Effects of Inspiratory Muscle Training (IMT) on Dyspnea in COPD During Pulmonary Rehabilitation: Randomized Controlled Trial.
Inspiratory muscle training

Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, or Clinical Trial

Lund University - Recruiting 35 years to 80 years.
- Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) and Cardiovascular Diseases in Smokers/Ex-Smokers Attending Primary Care - Longitudinal Study.

Pulmonary Disease, Chronic Obstructive Clinical Trial using placebo; ipratropium bromide

Boehringer Ingelheim - Recruiting 50 years to 75 years.
- Peri-operative Intervention With Nebulized Ipratropium Bromide in Chinese Patients With Chronic Obstructive Pulmonary Disease (COPD): a Randomized, Double-blind, Placebo-controlled, Parallel-group, Multi-centre Trial..
placebo; ipratropium bromide

Pulmonary Disease, Chronic Obstructive Clinical Trial using tiotropium; placebo; olodaterol

Boehringer Ingelheim - Recruiting 40 years or older.
- A Randomised, Double-blind, Placebo- and Active-controlled Parallel Group Study to Assess the Efficacy of 12 Weeks of Once Daily Treatment of Two Doses of Orally Inhaled Tiotropium + Olodaterol Fixed Dose Combination (Delivered by the Respimat Inhaler) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
tiotropium; placebo; olodaterol

Pulmonary Disease, Chronic Obstructive Clinical Trial using olodaterol; tiotropium; placebo

Boehringer Ingelheim - Recruiting 40 years or older.
- A Randomised, Double-blind, Placebo- and Active-controlled Parallel Group Study to Assess the Efficacy of 12 Weeks of Once Daily Treatment of Two Doses of Orally Inhaled Tiotropium+ Olodaterol Fixed Dose Combination (Delivered by the Respimat Inhaler) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
olodaterol; tiotropium; placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using olodaterol; tiotropium; Placebo

Boehringer Ingelheim - Recruiting 40 years or older.
- A Randomised, Placebo-controlled, Double-blind, Single Dose, Cross-over Study to Evaluate the Efficacy and Safety of Orally Inhaled Tiotropium + Olodaterol as Both a Fixed Dose Combination and a Free Combination (Both Delivered by the Respimatr Inhaler) in Patients With Chronic Obstructive Pulmonary Disease (COPD).
olodaterol; tiotropium; Placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using Placebo to BI 113608 high dose b.i.d.; Placebo to BI 113608 low dose b.i.d.; BI 113608 high dose b.i.d.; Placebo to BI 113608 medium dose b.i.d.; BI 113608 low dose b.i.d.; BI 113608 medium dose b.i.d.

Boehringer Ingelheim - Recruiting 40 years to 80 years.
- Randomized, Placebo-controlled, Double-blind Within Dose Groups, Multiple Rising-dose Study to Evaluate Safety, Tolerability, and PK of Oral BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With COPD Associated With Chronic Bronchitis.
Placebo to BI 113608 high dose b.i.d.; Placebo to BI 113608 low dose b.i.d.; BI 113608 high dose b.i.d.; Placebo to BI 113608 medium dose b.i.d.; BI 113608 low dose b.i.d.; BI 113608 medium dose b.i.d.

Pulmonary Disease, Chronic Obstructive Clinical Trial using Combivent Respimat via ventilator adapter

Boehringer Ingelheim - Recruiting 40 years or older.
- Open Label, Non-randomised, 1-day Trial to Characterize the Performance of an Adapter Device Designed to Permit Use of the Respimatr Inhaler Device With Patients Requiring Mechanical Ventilation..
Combivent Respimat via ventilator adapter

Pulmonary Disease, Chronic Obstructive Clinical Trial using Tiotropium Bromide 2.5 æg; Indacterol 300 æg; Tiotropium Bromide 18 æg; Indacterol 150 æg

Boehringer Ingelheim - Recruiting 40 years or older.
- Post-Marketing Observational Study of the Impact of Adherence to Treatment With Once-Daily Administered Long-Acting Bronchodilators (LABAs / LAMAs) on Patients Health Related Quality of Life in COPD Patients.
Tiotropium Bromide 2.5 æg; Indacterol 300 æg; Tiotropium Bromide 18 æg; Indacterol 150 æg

Pulmonary Disease, Chronic Obstructive Clinical Trial using Group1:Spirivar Respimatr; Group2:Hirobrizr/Oslifr/Onbrezr Breezhalerr

Boehringer Ingelheim - Recruiting 18 years or older.
- Cross-sectional Study to Assess the Handling , Patient Satisfaction, and Preference for Inhalation Devices in Patients With Chronic Obstructive Pulmonary Disease (COPD)..
Group1:Spirivar Respimatr; Group2:Hirobrizr/Oslifr/Onbrezr Breezhalerr

Pulmonary Disease, Chronic Obstructive Clinical Trial using fluticasone propionate; salmeterol; placebo; tiotropium; olodaterol

Boehringer Ingelheim - Recruiting 40 years or older.
- Randomized, Double-blind, Double-dummy, Active-controlled, 4 Period Complete Cross-over Study to Compare the Effect on Lung Function of 6 Weeks Once Daily Treatment With Orally Inhaled Tiotropium+Olodaterol Fixed Dose Combination Delivered by the Respimatr Inhaler vs. 6 Weeks Twice Daily Treatment With Fluticasone Propionate+Salmeterol Fixed Dose Combination Delivered by the Accuhalerr in Patients With Chronic Obstructive Pulmonary Disease (COPD).
fluticasone propionate; salmeterol; placebo; tiotropium; olodaterol

Chronic Obstructive Pulmonary Disease (COPD) With Cachexia Clinical Trial using Placebo; BYM338

Novartis - Recruiting 40 years to 80 years.
- A Randomized, Double Blind, Placebo Controlled, Multi-centre Study to Asses the Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of BYM338 in Chronic Obstructive Pulmonary Disease Patients With Cachexia.
Placebo; BYM338

COPD Clinical Trial using Ergometer Training; Motivation

Institut fr Pneumologie Hagen Ambrock eV - Recruiting 18 years to 80 years.
- German: Effekte Eines Telemonitorisch berwachten Ergometertrainings Bei Patienten Mit Einer COPD Nach Exazerbation: Eine Prospektiv Randomisierte Studie.
Ergometer Training; Motivation

COPD Clinical Trial using Hydrolyzed casein protein; Hydrolyzed casein protein + carbohydrates; Hydrolyzed casein protein + leucine; Hydrolyzed casein protein + carbohydrates + leucine

Texas A&M University - Recruiting 45 years or older.
- Casein Protein and Leucine Supplementation to Induce Anabolism in COPD Patients and Healthy Elderly.
Hydrolyzed casein protein; Hydrolyzed casein protein + carbohydrates; Hydrolyzed casein protein + leucine; Hydrolyzed casein protein + carbohydrates + leucine

COPD Clinical Trial using ASM-024; Placebo

Asmacure Lt‚e - Recruiting 40 years or older.
- A Randomized, Double-blind, Placebo-controlled, Two-Way Crossover Study to Evaluate the Safety, Tolerability and Clinical Activity of ASM-024 Administered by Dry Power Inhalation to Patients With GOLD 2 (Moderate) or GOLD 3 (Severe) Chronic Obstructive Pulmonary Disease (COPD).
ASM-024; Placebo

Chronic Obstructive Pulmonary Disease Clinical Trial using Home mechanical ventilation

Fundaci¢ Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau - Recruiting N/A to 80 years.
- Home Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease (COPD) Who Develop Nocturnal Hypercapnic Response Associated to Oxygen Therapy.
Home mechanical ventilation

Lung Cancer, Tuberculosis, Bronchiectasis, Pneumonia, Acute Bronc Clinical Trial using Chest X-ray; computed tomography of the chest; Bronchoscopy

University of Milan - Recruiting 18 years or older.
- Multicenter, Prospective, Observational Study on Epidemiology and Diagnosis of Haemoptysis.
Chest X-ray; computed tomography of the chest; Bronchoscopy

Chronic Obstructive Pulmonary Disease Clinical Trial using Levofloxacin 500mg

University of Monastir - Recruiting 18 years or older.
- Evaluation of Two Strategies of Antibiotic Treatment With Levofloxacin in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Short Treatment-versus Treatment Guided by Markers of Inflammation.
Levofloxacin 500mg

Chronic Obstructive Pulmonary Disease Clinical Trial using High flow therapy

Institut fr Pneumologie Hagen Ambrock eV - Recruiting 20 years to 80 years.
- Respiratory Physiology Measurements Under Transnasal High Flow Therapy in Patients With Tracheostoma After Long Term Ventilation.
High flow therapy

Chronic Obstructive Pulmonary Disease, or COPD Exacerbation Clinical Trial

Cantonal Hosptal, Baselland - Recruiting 40 years or older.
- Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort COPD-Management: Eine Klinisch-epidemiologische Verlaufsbeobachtung in Hausarztpraxen.

Pulmonary Disease, Chronic Obstructive Clinical Trial using fluticasone propionate/salmeterol 50/250mcg; fluticasone propionate/salmeterol placebo; tiotropium bromide 18mcg; tiotropium bromide placebo; fluticasone propionate/salmeterol 50/250mcg and tiotropium 18mcg

GlaxoSmithKline - Recruiting 40 years to 80 years.
- Evaluating the Control of COPD Symptoms in Patients Treated With Tiotropium Bromide 18mcg Once Daily Alone, ADOAIR 50/250mcg Twice Daily Alone or ADOAIR 50/250mcg Plus Tiotropium Bromide 18mcg.
fluticasone propionate/salmeterol 50/250mcg; fluticasone propionate/salmeterol placebo; tiotropium bromide 18mcg; tiotropium bromide placebo; fluticasone propionate/salmeterol 50/250mcg and tiotropium 18mcg

Chronic Obstructive Pulmonary Disease Clinical Trial using JNJ 49095397; Placebo

Janssen Research & Development, LLC - Recruiting 40 years to 80 years.
- A Phase 2, Randomized, Double-blind, Placebo-controlled, Efficacy and Safety Study of Inhaled JNJ 49095397 (RV568) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease.
JNJ 49095397; Placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using Spirometry

GlaxoSmithKline - Recruiting 40 years or older.
- Assessment of Comorbidities in Chronic Obstructive Pulmonary Disease (COPD) in European Symptomatic Subjects From Primary Care.
Spirometry

Pulmonary Disease, Chronic Obstructive Clinical Trial using FF/VI; Existing Maintenance Therapy

GlaxoSmithKline - Recruiting 40 years or older.
- A 12-month, Open Label, Randomised, Effectiveness Study to Evaluate Fluticasone Furoate (FF, GW685698)/Vilanterol (VI, GW642444) Inhalation Powder Delivered Once Daily Via a Novel Dry Powder Inhaler (NDPI) Compared With the Existing COPD Maintenance Therapy Alone in Subjects With Chronic Obstructive Pulmonary Disease (COPD).
FF/VI; Existing Maintenance Therapy

Pulmonary Disease, Chronic Obstructive Clinical Trial using fluticasone furoate/vilanterol; fluticasone furoate; vilanterol; Placebo

GlaxoSmithKline - Recruiting 40 years to 80 years.
- A Clinical Outcomes Study to Compare the Effect of Fluticasone Furoate/Vilanterol Inhalation Powder 100/25mcg With Placebo on Survival in Subjects With Moderate Chronic Obstructive Pulmonary Disease (COPD) and a History of or at Increased Risk for Cardiovascular Disease.
fluticasone furoate/vilanterol; fluticasone furoate; vilanterol; Placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using GSK2256294

GlaxoSmithKline - Recruiting 18 years or older.
- A Study to Evaluate the Effect of Age, Food and Gender on Tolerability and Pharmacokinetics of GSK2256294 Following a Single Oral Administration in Healthy Fed and Fasted Elderly Subjects. This Study Will Also Evaluate the Biliary Metabolites in Healthy Young Males Following a Single Dose of GSK2256294.
GSK2256294

Chronic Obstructive Pulmonary Disease Clinical Trial using Quercetin

University of Michigan - Recruiting 40 years to 80 years.
- Phase I/II Study to Determine the Safety and Efficacy of Quercetin in COPD Patients.
Quercetin

Pulmonary Hypertension, or Chronic Obstructive Pulmonary Disease Clinical Trial using Inhaled NO; Placebo

INO Therapeutics - Recruiting 40 years to 80 years.
- A Placebo-Controlled, Double-Blind, Parallel, Randomized, Two-Part, Clinical Dose-Confirming Study Of Pulsed, Inhaled Nitric Oxide (iNO) In Subjects With World Health Organization (WHO) Group 3 Pulmonary Hypertension (PH) Associated With Chronic Obstructive Pulmonary Disease (COPD) On Long Term Oxygen Therapy (LTOT) INHALE 1.
Inhaled NO; Placebo

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial using AZD4721; Placebo; AZD5069

AstraZeneca - Recruiting 18 years to 50 years.
- A Phase I Study in Healthy Volunteers to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD4721 After Once Daily Administration of Multiple Ascending Doses for 10 Days, and an Open-label Comparison With the Pharmacodynamics of AZD5069 Given Twice Daily for 3 Days.
AZD4721; Placebo; AZD5069

Asthma,, or Pulmonary Disease, Chronic Obstructive Clinical Trial using Medical tests

Janssen Research & Development, LLC - Recruiting 18 years to 70 years.
- A Multicenter Longitudinal Study for Disease Profiling of Asthma and Chronic Obstructive Pulmonary Disease.
Medical tests

Pulmonary Disease, Chronic Obstructive Clinical Trial using Fatiguing exercise

Laval University - Recruiting 50 years to 75 years.
- Muscle Oxygenation and Metabolism in Response to a Localized Fatigue-inducing Exercise in Patients With Chronic Obstructive Pulmonary Disease.
Fatiguing exercise

Chronic Obstructive Pulmonary Disease, or Metabolic Syndrome Clinical Trial using Roflumilast; Placebo

Laval University - Recruiting 40 years to 80 years.
- Impact of Roflumilast on Visceral Adiposity and MetaBolic Profile in Chronic Obstructive Lung Disease: a Randomized and Controlled Trial: the RAMBO Trial..
Roflumilast; Placebo

Chronic Obstructive Pulmonary Disease Clinical Trial

University of British Columbia - Recruiting 19 years to 95 years.
- Clinical Implementation and Outcomes Evaluation of Blood-Based Biomarkers for Chronic Obstructive Pulmonary Disease Management.

Pulmonary Disease, Chronic Obstructive Clinical Trial using Self-Management and Motivational Interviewing

Mayo Clinic - Recruiting 40 years or older.
- Multicomponent Intervention to Decrease COPD-related Hospitalizations.
Self-Management and Motivational Interviewing

HIV, COPD, Chronic Obstructive Pulmonary Disease, or Smoking Clinical Trial using Examination of the interaction of HIV directly on the small airway epithelium

Weill Medical College of Cornell University - Recruiting 18 years or older.
- HIV-related Accelerated Aging of the Airway Epithelium.
Examination of the interaction of HIV directly on the small airway epithelium

COPD, Exercise, or Resistance Training Clinical Trial using Resistance training; Endurance training

Rigshospitalet, Denmark - Recruiting 40 years to 80 years.
- The Effects of Physical Exercise Training on in Patients With Chronic Obstructive Pulmonary Disease.
Resistance training; Endurance training

Pulmonary Disease, Chronic Obstructive Clinical Trial using Telemedicine

Aalborg University - Recruiting N/A or older.
- Effectiveness and Cost-effectiveness of Telemedicine for Chronic Obstructive Pulmonary Disease: The Danish 'TeleCare North' Pragmatic Cluster-randomized Trial..
Telemedicine

Pulmonary Disease, Chronic Obstructive Clinical Trial using Fluticasone Furoate/Vilanterol; Vilanterol; Placebo

GlaxoSmithKline - Recruiting 40 years or older.
- A 24-week Study to Evaluate the Effect of Fluticasone Furoate/Vilanterol 100/25 Mcg Inhalation Powder Delivered Once-daily Via a Novel Dry Powder Inhaler on Arterial Stiffness Compared With Placebo and Vilanterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)..
Fluticasone Furoate/Vilanterol; Vilanterol; Placebo

Invasive Pulmonary Aspergillosis, or Chronic Obstructive Pulmonar Clinical Trial using caspofungin

The First Affiliated Hospital of Guangzhou Medical University - Recruiting 18 years or older.
- Prospective, Open-label Study of the Efficacy and Safety of Caspofungin for the Treatment of Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease.
caspofungin

Pulmonary Disease, Chronic Obstructive Clinical Trial using tiotropium bromide; Placebo

Boehringer Ingelheim Pharmaceuticals - Recruiting 40 years or older.
- A Randomized, Placebo-controlled, Double-blind, Parallel Group, Multi Center Study to Assess the Safety and Efficacy of Tiotropium Bromide (18 æg) Delivered Via the HandiHalerr in Chronic Obstructive Pulmonary Disease (COPD) Subjects Recovering From Hospitalization for an Acute Exacerbation (Hospital Discharge Study 1).
tiotropium bromide; Placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using self-monitoring for patients with severe COPD; nurse-monitoring for patients with severe COPD

Regione Veneto - Recruiting 18 years or older.
- RENEWING HEALTH - Large Scale Pilot in Veneto Region: Life-long Monitoring in COPD.
self-monitoring for patients with severe COPD; nurse-monitoring for patients with severe COPD

Chronic Obstructive Pulmonary Disease Clinical Trial

AstraZeneca - Recruiting N/A or older.
- Oxis 9mcg Turbuhaler Clinical Experience Investigation.

Chronic Obstructive Pulmonary Disease Clinical Trial

AstraZeneca - Recruiting N/A or older.
- Symbicort Turbuhaler 30/60 Special Clinical Experience Investigation for Long-term Use for COPD Patients.

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial using QVA149; Tiotropium; placebo

Novartis - Recruiting 40 years or older.
- A Placebo and Active Controlled Study to Assess the Long-term Safety of Once Daily QVA149 for 52 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients With Moderate to Severe Airflow Limitation.
QVA149; Tiotropium; placebo

Chronic Obstructive Pulmonary Disease Clinical Trial using Adipose-Derived Stem Cell (ADSC) Therapy

Ageless Regenerative Institute - Recruiting 18 years to 80 years.
- An Open-label, Non-Randomized, Multi-Center Study to Assess the Safety and Effects of Intra-venous Implantation of Autologous Adipose-Derived Stem Cells in Patients With Chronic Obstructive Pulmonary Disease.
Adipose-Derived Stem Cell (ADSC) Therapy

Chronic Obstructive Pulmonary Disease, or Patients Hospitalized f Clinical Trial using PEP

University Hospital, Brest - Recruiting 18 years or older.
- Frequency of Diagnostic Symptomatic Pulmonary Embolism's in Patients Hospitalized for Clinical Exacerbation of Chronic Obstructive Pulmonary Disease (COPD).
PEP

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial using NVA237; Long-acting beta 2-agonist (LABA); Placebo

Novartis - Recruiting 40 years or older.
- A Multi-center, Randomized, Double-blind, 52-week Study to Assess the Safety of NVA237 Compared to QAB149 in Patients With Chronic Obstructive Pulmonary Disease (COPD) Who Have Moderate to Severe Airflow Limitation.
NVA237; Long-acting beta 2-agonist (LABA); Placebo

Diabetes Mellitus (DM), Congestive Heart Failure (CHF), or Chroni Clinical Trial using Community Paramedicine; Usual Care

St. Michael's Hospital, Toronto - Recruiting 18 years or older.
- The Expanding Paramedicine in the Community (Study).
Community Paramedicine; Usual Care

Pulmonary Disease, Chronic Obstructive Clinical Trial using CNTO 6785; Placebo

Janssen Research & Development, LLC - Recruiting 40 years to 75 years.
- A Randomized, Placebo Controlled Double-Blind, Multi-Center, Phase II Study to Assess the Efficacy and Safety of CNTO6785 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease.
CNTO 6785; Placebo

Pulmonary Disease, Chronic Obstructive Clinical Trial using tiotropium bromide; Placebo

Boehringer Ingelheim Pharmaceuticals - Recruiting 40 years or older.
- A Randomized, Placebo-controlled, Double-blind, Parallel Group, Multi Center Study to Assess the Safety and Efficacy of Tiotropium Bromide (18 æg) Delivered Via the HandiHalerr in Chronic Obstructive Pulmonary Disease (COPD) Subjects Recovering From Hospitalization for an Acute Exacerbation (Hospital Discharge Study 2).
tiotropium bromide; Placebo

Remote Patient Monitoring in COPD Patients Clinical Trial using Remote Patient Monitoring; Usual care

Novartis - Recruiting 40 years or older.
- A 52-week Multi-center Randomized Trial to Evaluate Remote Patient Monitoring Using the EXACT Patient-reported Outcome Tool on Reduction of Hospitalizations From Exacerbations in Patients With Chronic Obstructive Pulmonary Disease as Compared to Those Managed by Usual Care.
Remote Patient Monitoring; Usual care

Pulmonary Disease, Chronic Obstructive Clinical Trial using Aclidinium Bromide / Formoterol Fumarate; Salmeterol / Fluticasone

Almirall, S.A. - Recruiting 40 years or older.
- A Randomised, Double-blind, Double-dummy, Active-controlled Study Evaluating the Efficacy, Safety and Tolerability of Twice-daily Aclidinium Bromide/Formoterol Fumarate Compared With Twice-daily Salmeterol/Fluticasone Propionate for 24 Weeks Treatment in Symptomatic Patients With Chronic Obstructive Pulmonary Disease (COPD).
Aclidinium Bromide / Formoterol Fumarate; Salmeterol / Fluticasone

COPD Clinical Trial using Peforomist-Placebo; Perforomist, nebulization, COPD

Dey - Recruiting 40 years or older.
- A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety of Long-Term Use of Perforomistr (Formoterol Fumarate) Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease (COPD).
Peforomist-Placebo; Perforomist, nebulization, COPD

Pulmonary Disease, Chronic Obstructive Clinical Trial using Fluticasone Furoate; Vilanterol

GlaxoSmithKline - Recruiting 40 years or older.
- A Randomised, Double-Blind, Placebo-Controlled, Cross-Over, Single-Centre Study to Investigate the Acute Lung Deflation Effects of Fluticasone Furoate/Vilanterol Inhalation Powder 100/25mcg Once Daily on Cardiac Biventricular Function and Arterial Stiffness in Adults With Chronic Obstructive Pulmonary Disease (COPD).
Fluticasone Furoate; Vilanterol

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial using Implementation educational programme

Medical Universtity of Lodz - Recruiting 18 years or older.
- Tailored Implementation for Chronic Diseases..
Implementation educational programme

Chronic Obstructive Pulmonary Disease Clinical Trial using niv plus oxygen therapy; oxygen therapy

Guangzhou Institute of Respiratory Disease - Recruiting 30 years to 80 years.
- The Efficacy of Non-invasive Mechanical Ventilation as a Rescue Therapy for Relieving Dyspnea in Patients With Stable Severe COPD.
niv plus oxygen therapy; oxygen therapy

Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmo Clinical Trial using Life Completion; Attention Control

Department of Veterans Affairs - Recruiting 18 years or older.
- Outlook: An Intervention to Improve Quality of Life in Serious Illness Study.
Life Completion; Attention Control

Non Small Cell Lung Cancer, or Chronic Obstructive Pulmonary Dise Clinical Trial

University of Virginia - Recruiting 18 years or older.
- The Use of Circulating Tumor Cells in Non-Small Cell Lung Cancer: Novel Isolation Methods and Clinical Applications.

Chronic Obstructive Pulmonary Disease Clinical Trial using NVA237; Tiotropium; Placebo to NVA237; Placebo to tiotropium; Salbutamol

Novartis - Recruiting 40 years or older.
- A Randomized, Double-blind, Multicenter, 2-period Single-dose Cross-over Study to Assess the Early Bronchodilation of Glycopyrronium Bromide (44 æg o.d.) Compared to Tiotropium (18 æg. o.d.) in Patients With Moderate to Severe COPD (FAST Study).
NVA237; Tiotropium; Placebo to NVA237; Placebo to tiotropium; Salbutamol

Chronic Obstructive Pulmonary Disease, COPD, or Chronic Bronchiti Clinical Trial using Inhaled HS home treatment

University of North Carolina, Chapel Hill - Recruiting 40 years to 80 years.
- Novel Therapies for Muco-Obstructive Lung Diseases: Sustained Effects of Hypertonic Saline on Mucociliary Clearance and Clinical Tolerability in Subjects With Chronic Bronchitis.
Inhaled HS home treatment

COPD Clinical Trial using bambuterol; Placebo

The First Affiliated Hospital of Guangzhou Medical University - Recruiting 40 years to 80 years.
- A 12-week, Double-blind, Multicenter, 3-crossover, Placebo Controlled and Randomized Trial to Investigate the Efficacy and Safety of 10mg and 5mg Bambuterol Tablets Once Daily in Patients With Chronic Obstructive Pulmonary Disease (COPD).
bambuterol; Placebo

Chronic Obstructive Pulmonary Disease Clinical Trial using Fiberoptic bronchoscopy; blood draw; intravenous catheter

Department of Veterans Affairs - Recruiting 18 years to 80 years.
- Apoptotic Cell Ingestion by Normal Human Alveolar Macrophages.
Fiberoptic bronchoscopy; blood draw; intravenous catheter

Lung Cancer, Chronic Obstructive Pulmonary Disease, Emphysema, or Clinical Trial using Lung surgery

Hopital Foch - Recruiting 18 years to 75 years.
- Relationship Between Blood, Hair and Lung Metals/Metalloids Concentration (Cadmium, Iron, Copper, Nickel, Chrome, Arsenic, Vanadium, Beryllium, and Zinc) and Lung Cancer or Chronic Obstructive Pulmonary Disease..
Lung surgery

High Blood Pressure Clinical Trial using Placebo; Nebivolol

University of Chicago - Recruiting 40 years to 75 years.
- Nebivolol in Chronic Obstructive Pulmonary Disease.
Placebo; Nebivolol

Chronic Obstructive Pulmonary Disease, or Lung Cancer Clinical Trial

Katholieke Universiteit Leuven - Recruiting 25 years or older.
- Serum, Plasma, DNA and Tissue Bank of Patients With Chronic Obstructive Pulmonary Disease, Lung Cancer and Smoking Controls..

Lung Transplantation, or Chronic Obstructive Pulmonary Disease Clinical Trial

Katholieke Universiteit Leuven - Recruiting 18 years to 80 years.
- Confocal Laser Micro-endoscopy: New Insights in COPD and Lung Transplant Recipients.

Chronic Obstructive Pulmonary Disease Clinical Trial

Katholieke Universiteit Leuven - Recruiting 40 years or older.
- Adherence to Medication and Its Impact on COPD Exacerbations: The AMICE Prospective Study.

Pulmonary Disease, Chronic Obstructive, or Lung Diseases, Obstruc Clinical Trial using Blood drawing; Bronchoalveolar lavage during indicated bronchoscopy

University of Michigan - Recruiting 40 years or older.
- Innate and Adaptive Immunity in COPD Exacerbations: Clinically-Indicated Bronchoscopies.
Blood drawing; Bronchoalveolar lavage during indicated bronchoscopy

Chronic Obstructive Pulmonary Disease Clinical Trial using Altitude exposure

University of Zurich - Recruiting 18 years to 75 years.
- Nocturnal Breathing and Sleep in Patients With Chronic Obstructive Pulmonary Disease Staying at Altitude.
Altitude exposure

Chronic Obstructive Pulmonary Disease, or Type 2 Diabetes Clinical Trial using Tool; Self-management Support Program

Maastricht University Medical Center - Recruiting 40 years to 70 years.
- RCT It's LiFe! to Evaluate the Effectiveness of the Monitoring and Feedback Tool and the Corresponding Counseling Protocol (Self-management Support Program) to be Executed by Practice Nurses in Primary Care.
Tool; Self-management Support Program

Chronic Obstructive Pulmonary Disease, or Multiple Comorbidity Clinical Trial using 40 minute standardized education session; Individualized action plan; Individualized care plan; Standardized reinforcement/motivational interviewing and action plan teach-back sessions; Tele-home monitoring; Coordinated and improved communication; Priority access; Dictated patient summary; in-hospital rehabilitation/self-management program; Smoking cessation; Action plan Respirologist; Web based self management materials

Toronto East General Hospital - Recruiting 50 years or older.
- Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities: A Randomized Controlled Trial.
40 minute standardized education session; Individualized action plan; Individualized care plan; Standardized reinforcement/motivational interviewing and action plan teach-back sessions; Tele-home monitoring; Coordinated and improved communication; Priority access; Dictated patient summary; in-hospital rehabilitation/self-management program; Smoking cessation; Action plan Respirologist; Web based self management materials

COPD Clinical Trial using Lysozyme hydrochloride; Placebo

Eisai Inc. - Recruiting 20 years to 84 years.
- Effects of Lysozyme On Acute Exacerbation of Chronic Obstructive Pulmonary Disease : A Randomised Placebo-Controlled Study.
Lysozyme hydrochloride; Placebo

Chronic Obstructive Pulmonary Disease Clinical Trial

Columbia University - Recruiting 50 years to 75 years.
- Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary (MESA-COPD).

CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA, or HEALTHY SUBJECT Clinical Trial using SALBUTAMOL

Imperial College London - Recruiting 18 years or older.
- Improving Inhaler Treatment and Small Airways Assessment in Chronic Obstructive Pulmonary Disease (COPD).
SALBUTAMOL

Hypertension, Pulmonary, or Pulmonary Disease, Chronic Obstructiv Clinical Trial

Wissenschaftliches Institut Bethanien e.V - Recruiting 18 years or older.
- Chronisch Obstruktive Lungenerkrankung Und Pulmonale Hypertonie: Pr„valenz Und Lebensqualit„t.

COPD Clinical Trial using Exercise training

Universidade Norte do Paraná - Recruiting 50 years or older.
- Effects of Two Training Protocols in Physical Activity in Daily Life and Balance in Patients With COPD: Land Versus Water.
Exercise training

Chronic Obstructive Pulmonary Disease (COPD) Clinical Trial

Cardiff University - Recruiting 35 years to 80 years.
- Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE).

Chronic Obstructive Pulmonary Disease and Allied Conditions Clinical Trial using Roflumilast; Placebo

LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology - Recruiting 40 years to 80 years.
- Effects of ROFLUMILAST on Markers of Subclinical Atherosclerosis In Stable COPD; the ELASTIC-trial.
Roflumilast; Placebo

Chronic Obstructive Pulmonary Disease Clinical Trial using AVAPS-AE; AVAPS-AE mode of ventilator therapy

Philips Respironics - Recruiting 18 years or older.
- Engineering Validation of the AVAPS-AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD)Patients.
AVAPS-AE; AVAPS-AE mode of ventilator therapy

Chronic Obstructive Pulmonary Disease Clinical Trial using theophylline; placebo

Hospital Son Espases - Recruiting 45 years to 90 years.
- Multicenter 52 Weeks Double Blind Placebo-controlled Trial for the Assessment of Theophylline on Top of Combination Therapy in Severe COPD.
theophylline; placebo

Obesity, or Chronic Obstructive Pulmonary Disease Clinical Trial using Ventilator setting changes

Bridgeport Hospital - Recruiting 18 years or older.
- What Ventilator Settings Are Most Comfortable for Patients With COPD or Obesity..
Ventilator setting changes

Chronic Obstructive Pulmonary Disease Clinical Trial

UPECLIN HC FM Botucatu Unesp - Recruiting 40 years to 95 years.
- Three-Years Follow-up of Diagnostic and Prognostic Markers in Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease, or Asthma Clinical Trial

Bispebjerg Hospital - Recruiting 18 years or older.
- Trefoil Peptides in Lung Diseases.

Emphysema, or Chronic Obstructive Pulmonary Disease Clinical Trial using Bronchoscopic Lung Volume Reduction (BLVR)

LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology - Recruiting 40 years to 75 years.
- A Multi-Center, Prospective, Clinical Trial Designed to Study the Efficacy of One-Way Valve Implantation Based on a New Treatment Algorithm in Patients With Heterogeneous Emphysema.
Bronchoscopic Lung Volume Reduction (BLVR)

Chronic Obstructive Pulmonary Disease, or Acute Respiratory Failu Clinical Trial

University Hospital, Grenoble - Recruiting 18 years or older.
- Predictive Factors of Endothelial Function in Chronic Obstructive Disease Patients at the End of a Acute Exacerbation..

Chronic Obstructive Pulmonary Disease Clinical Trial

Imperial College London - Recruiting 38 years to 80 years.
- The Effect of Inhaled Mannitol on Ciliary Beat Frequency in COPD Patients.