178 results found.

Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesop Clinical Trial using radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Trial Evaluating The Addition Of Trastuzumab To Trimodality Treatment Of Her2-Overexpressing Esophageal Adenocarcinoma.
radiation therapy; paclitaxel; carboplatin; trastuzumab; therapeutic conventional surgery; laboratory biomarker analysis; quality-of-life assessment

Menopause, or Quality of Life Clinical Trial using black cohosh extract; Placebo

Navamindradhiraj University - Recruiting 40 years or older.
- Black Cohosh Extract for the Treatment of Moderate to Severe Menopausal Symptoms: a Randomized-placebo Controlled Trial.
black cohosh extract; Placebo

Colorectal Cancer Metastatic Clinical Trial using AFLIBERCEPT AVE0005; FOLFIRI

Sanofi - Recruiting 18 years or older.
- A Multicenter, Single Arm, Open Label Clinical Trial to Evaluate the Safety and Health-Related Quality of Life of Aflibercept in Patients With Metastatic Colorectal Cancer (mCRC) Previously Treated With an Oxaliplatin-Containing Regimen.
AFLIBERCEPT AVE0005; FOLFIRI

Quality of Life Clinical Trial using quality of life

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Brody Belt - Alternative Method of Securing a Patient's Urinary Drainage Bag.
quality of life

Endometriosis, Botulinum Toxin A, Chronic Pelvic Pain, Pelvic Mus Clinical Trial using Botuninum toxin A

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 50 years.
- The Effectiveness of Botulinum Toxin on Persistent Pelvic Pain in Women With Endometriosis.
Botuninum toxin A

Prostate Cancer, Erectile Dysfunction Following Radical Prostatec Clinical Trial using Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Case Comprehensive Cancer Center - Recruiting 21 years or older.
- Improving Erectile Function and Quality of Life After Prostate Cancer Treatment.
Cognitive-behavioral Meetings; sildenafil citrate; Vacuum Constriction Device

Pulmonary Disease, Chronic Obstructive Clinical Trial using Tiotropium Bromide 2.5 æg; Indacterol 300 æg; Tiotropium Bromide 18 æg; Indacterol 150 æg

Boehringer Ingelheim - Recruiting 40 years or older.
- Post-Marketing Observational Study of the Impact of Adherence to Treatment With Once-Daily Administered Long-Acting Bronchodilators (LABAs / LAMAs) on Patients Health Related Quality of Life in COPD Patients.
Tiotropium Bromide 2.5 æg; Indacterol 300 æg; Tiotropium Bromide 18 æg; Indacterol 150 æg

Atrial Fibrillation Clinical Trial using Rivaroxaban (Xarelto, BAY59-7939)

Bayer - Recruiting 18 years or older.
- Satisfaction and Quality of Life in Patients With a Diagnosis of Non Valvular Atrial Fibrillation Who Take Rivaroxaban for Stroke Prevention.
Rivaroxaban (Xarelto, BAY59-7939)

Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer Clinical Trial using exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE).
exercise intervention; counseling intervention; educational intervention; laboratory biomarker analysis; questionnaire administration; study of socioeconomic and demographic variables; fatigue assessment and management; quality-of-life assessment

Stage I Multiple Myeloma, Stage II Multiple Myeloma, or Stage III Clinical Trial using ixazomib; cyclophosphamide; dexamethasone; pharmacological study; questionnaire administration; quality-of-life assessment

Mayo Clinic - Recruiting 18 years or older.
- Phase 1/2 Trial of MLN9708 in Combination With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma.
ixazomib; cyclophosphamide; dexamethasone; pharmacological study; questionnaire administration; quality-of-life assessment

Lymphedema, Stage IA Cervical Cancer, Stage IA Endometrial Carcin Clinical Trial using therapeutic lymphadenectomy; therapeutic conventional surgery; therapeutic laparoscopic surgery; study of high risk factors; questionnaire administration; psychosocial assessment and care; quality-of-life assessment

Gynecologic Oncology Group - Recruiting 18 years or older.
- The Lymphedema and Gynecologic Cancer (LEG) Study: Incidence, Risk Factors, and Impact in Newly Diagnosed Patients.
therapeutic lymphadenectomy; therapeutic conventional surgery; therapeutic laparoscopic surgery; study of high risk factors; questionnaire administration; psychosocial assessment and care; quality-of-life assessment

Brenner Tumor, Ovarian Clear Cell Cystadenocarcinoma, Ovarian End Clinical Trial using behavioral dietary intervention; exercise intervention; counseling intervention; educational intervention; compliance monitoring; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis

Gynecologic Oncology Group - Recruiting 18 years or older.
- Can Diet and Physical Activity Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer Progression-Free Survival?.
behavioral dietary intervention; exercise intervention; counseling intervention; educational intervention; compliance monitoring; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis

Cancer Survivor Clinical Trial using carvedilol; placebo; pharmacogenomic studies; laboratory biomarker analysis; quality-of-life assessment; polymorphism analysis; microarray analysis; polymerase chain reaction; enzyme-linked immunosorbent assay; questionnaire administration

City of Hope Medical Center - Recruiting 16 years or older.
- Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Congestive Heart Failure (PREVENT-CHF): A Phase IIB Randomized Placebo-Controlled Trial.
carvedilol; placebo; pharmacogenomic studies; laboratory biomarker analysis; quality-of-life assessment; polymorphism analysis; microarray analysis; polymerase chain reaction; enzyme-linked immunosorbent assay; questionnaire administration

Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Pre Clinical Trial using brentuximab vedotin; doxorubicin hydrochloride; vinblastine; dacarbazine; quality-of-life assessment; DNA analysis; RNA analysis; fludeoxyglucose F 18; positron emission tomography; laboratory biomarker analysis; immunohistochemistry staining method; polymorphism analysis

Northwestern University - Recruiting 60 years or older.
- A Phase II Trial of Sequential SGN-35 Therapy With Adriamycin, Vinblastine, and Dacarbazine (S-AVD) for Older Patients With Untreated Hodgkin Lymphoma.
brentuximab vedotin; doxorubicin hydrochloride; vinblastine; dacarbazine; quality-of-life assessment; DNA analysis; RNA analysis; fludeoxyglucose F 18; positron emission tomography; laboratory biomarker analysis; immunohistochemistry staining method; polymorphism analysis

Rheumatoid Arthritis Clinical Trial

AbbVie - Recruiting 18 years or older.
- Long Term Documentation of the Safety and Efficacy as Well as the Effects on Quality of Life and Work Productivity in Patients With Rheumatoid Arthritis Under HUMIRAr (Adalimumab) in Routine Clinical Practice (AGIL).

Quality of Life, or Sexual Activity Clinical Trial using transvaginal resection of Uterine Scar

First Affiliated Hospital, Sun Yat-Sen University - Recruiting N/A or older.
- Safety ,Validity and Quality of (Sexual)Life of Vaginal Operation in The Treatment Of Previous Cesarean Scar Defect.
transvaginal resection of Uterine Scar

Stage I Ovarian Epithelial Cancer, Stage I Primary Peritoneal Cav Clinical Trial using pharmacological study; questionnaire administration; assessment of therapy complications; quality-of-life assessment; carboplatin; paclitaxel; filgrastim

Gynecologic Oncology Group - Recruiting 75 years or older.
- Chemotherapy Toxicity in Elderly Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer.
pharmacological study; questionnaire administration; assessment of therapy complications; quality-of-life assessment; carboplatin; paclitaxel; filgrastim

Ductal Breast Carcinoma in Situ, Estrogen Receptor-negative Breas Clinical Trial using therapeutic conventional surgery; radiation therapy; quality-of-life assessment

Roswell Park Cancer Institute - Recruiting 50 years or older.
- Phase II Trial of Single Fraction Radiation Therapy (SFRT) at Roswell Park Cancer Institute for Select Patients With Early Stage Breast Cancer.
therapeutic conventional surgery; radiation therapy; quality-of-life assessment

Hematologic Malignancies, or Other Diagnoses, Comorbidities, and Clinical Trial

Fred Hutchinson Cancer Research Center - Recruiting 19 years or older.
- Prospective Assessment of Associations Between Pre-transplant Comorbidities and Post-transplant Toxicities and Quality of Life.

Phenylketonuria, or Mild Hyperphenylalaninemia Clinical Trial

The Hospital for Sick Children - Recruiting 18 years or older.
- Neuropsychological and Quality of Life Outcomes in Untreated Adults With Mild Hyperphenylalaninemia With Phenylalanine Levels Between 360 and 600 æmol/L..

Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Ne Clinical Trial using questionnaire administration; cognitive assessment; psychosocial assessment and care; quality-of-life assessment

Children's Oncology Group - Recruiting 1 Month to 21 years.
- Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer.
questionnaire administration; cognitive assessment; psychosocial assessment and care; quality-of-life assessment

Lymphoma Clinical Trial using socio-aesthetic care

University Hospital, Angers - Recruiting 18 years to 65 years.
- Impact of Socio-aesthetic Care in the Quality of Life of Patients Treated for Lymphoma During and After Hospitalization.
socio-aesthetic care

Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Clinical Trial using standard follow-up care; medical chart review; quality-of-life assessment

Fred Hutchinson Cancer Research Center - Recruiting 18 years to 75 years.
- Phase 2 Study of Early Discharge and Outpatient Management of Adult Patients Following Intensive Chemotherapy for MDS and Non-APL AML.
standard follow-up care; medical chart review; quality-of-life assessment

Cataract Clinical Trial using No Clinical Follow up; Quality of Life questionnaire; Patient satisfaction Questionnaire

South Devon Healthcare NHS Foundation Trust - Recruiting 40 years or older.
- Randomised Trial of Four to Six Week Follow Ups vs no Medical Follow up After Uncomplicated Cataract Extraction.
No Clinical Follow up; Quality of Life questionnaire; Patient satisfaction Questionnaire

Compression Fracture of Vertebral Body, Osteoporosis, or Cancer Clinical Trial using Balloon kyphoplasty

Medtronic Spinal and Biologics - Recruiting 65 years or older.
- A Prospective and Multicenter Evaluation of Outcomes for Quality of Life and Activities of Daily Living for Balloon Kyphoplasty in the Treatment of Vertebral Compression Fractures.
Balloon kyphoplasty

Macular Degeneration Clinical Trial using VEGF Trap-Eye (BAY86-5321)

Bayer - Recruiting N/A or older.
- Special Drug Use Investigation of EYLEA for Quality of Life.
VEGF Trap-Eye (BAY86-5321)

Colorectal Cancer, Dermatologic Complications, Lung Cancer, or Th Clinical Trial using assessment of therapy complications; psychosocial assessment and care; quality-of-life assessment

Southwest Oncology Group - Recruiting N/A or older.
- S1013: A Prospective Study of Epidermal Growth Factor Receptor (HER-1/EGFR) Inhibitor-Induced Dermatologic Toxicity: Validation of the Functional Assessment of Cancer Therapy-EGFRI 18(FACT-EGFRI 18) Questionnaire for EGFRI-Induced Skin Toxicities.
assessment of therapy complications; psychosocial assessment and care; quality-of-life assessment

Anxiety Disorder, Recurrent Non-small Cell Lung Cancer, or Stage Clinical Trial using counseling intervention; questionnaire administration; quality-of-life assessment

Stanford University - Recruiting N/A or older.
- Intervention Development for Anxiety in Metastatic NSCLC Patients and Their Caregivers.
counseling intervention; questionnaire administration; quality-of-life assessment

Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lu Clinical Trial using photon beam radiation therapy; proton beam radiation therapy; paclitaxel; carboplatin; etoposide; cisplatin; quality-of-life assessment; questionnaire administration

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Phase III Randomized Trial Comparing Overall Survival After Photon Versus Proton Chemoradiotherapy for Inoperable Stage II-IIIB NSCLC.
photon beam radiation therapy; proton beam radiation therapy; paclitaxel; carboplatin; etoposide; cisplatin; quality-of-life assessment; questionnaire administration

Bronchiolitis Obliterans, Chronic Graft Versus Host Disease, Leuk Clinical Trial using Montelukast sodium; Flow cytometry; Laboratory biomarker analysis; Quality-of-life assessment

National Institutes of Health Clinical Center (CC) - Recruiting 6 years to 80 years.
- Multi-Institutional Prospective Phase II Study of Montelukast for the Treatment of Bronchiolitis Obliterans Following Allogeneic or Autologous Stem Cell Transplantation in Children and Adults.
Montelukast sodium; Flow cytometry; Laboratory biomarker analysis; Quality-of-life assessment

Cancer Caregivers, Health Related Quality of Life, or Informal Ca Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Web-Based Patient Reported Outcome Measurement Information System to Explore Burden, and Stress in Cancer Caregivers (BaSiC2).

Quality of Life, or Breakthrough Cancer Pain Clinical Trial using Fentanyl

Galena Biopharma, Inc. - Recruiting 18 years or older.
- Rapid Evaluation of Lifestyle, Independence, and Elimination of Breakthrough Cancer Pain With Freedom From Oral Discomfort Through the Use of Abstralr (Fentanyl) Sublingual Tablets.
Fentanyl

Ductal Breast Carcinoma in Situ, Invasive Ductal Breast Carcinoma Clinical Trial using Behavioral dietary intervention; Therapeutic conventional surgery; Radiation therapy; Counseling intervention; Quality-of-life assessment

Thomas Jefferson University - Recruiting 18 years or older.
- A Feasibility Pilot Trial Evaluating Caloric Restriction for Oncology Research in Early Stage Breast Cancer Patients.
Behavioral dietary intervention; Therapeutic conventional surgery; Radiation therapy; Counseling intervention; Quality-of-life assessment

Periodontal Disease, or Quality of Life Clinical Trial

University of Michigan - Recruiting N/A or older.
- Oral Health in Breast Cancer Survivors on Aromatase Inhibitors.

Fallopian Tube Cancer, Metastatic Cancer, Ovarian Cancer, or Peri Clinical Trial using carboplatin; cisplatin; paclitaxel; quality-of-life assessment

NCIC Clinical Trials Group - Recruiting 18 years or older.
- A Phase II/III Study of Intraperitoneal (IP) Plus Intravenous (IV) Chemotherapy Versus IV Carboplatin Plus Paclitaxel in Patients With Epithelial Ovarian Cancer Optimally Debulked at Surgery Following Neoadjuvant Intravenous Chemotherapy.
carboplatin; cisplatin; paclitaxel; quality-of-life assessment

B-cell Childhood Acute Lymphoblastic Leukemia, Philadelphia Chrom Clinical Trial using doxorubicin hydrochloride; cytarabine; vincristine sulfate; dexamethasone; pegaspargase; methotrexate; mercaptopurine tablet; leucovorin calcium; cyclophosphamide; thioguanine; quality-of-life assessment; questionnaire administration; laboratory biomarker analysis

Children's Oncology Group - Recruiting 1 year to 30 years.
- Treatment of Patients With Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL).
doxorubicin hydrochloride; cytarabine; vincristine sulfate; dexamethasone; pegaspargase; methotrexate; mercaptopurine tablet; leucovorin calcium; cyclophosphamide; thioguanine; quality-of-life assessment; questionnaire administration; laboratory biomarker analysis

Cancer, or Quality of Life Clinical Trial using self-completion questionnaire

Hospices Civils de Lyon - Recruiting 18 years or older.
- Preliminary Study of Financial Distress and Quality of Life in Patients With Advanced Cancer.
self-completion questionnaire

Dementia, Malnutrition, Depression, Pain, or Quality of Life Clinical Trial using Empowerment; Conversation with nurse

Herlev Hospital - Recruiting 65 years or older.
- Cross-sectorial Patient Participation in Prevention of Loss of Functions in Older Short-stay Medical Patients.
Empowerment; Conversation with nurse

Malignant Neoplasm Clinical Trial using music therapy; caregiver-related intervention or procedure; questionnaire administration; quality-of-life assessment

Children's Oncology Group - Recruiting 11 years to 24 years.
- Music Video for AYA-Parent Communication and Resilience.
music therapy; caregiver-related intervention or procedure; questionnaire administration; quality-of-life assessment

Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Ac Clinical Trial using supersaturated calcium phosphate rinse; placebo; questionnaire administration; quality-of-life assessment

Children's Oncology Group - Recruiting 4 years to 21 years.
- A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation.
supersaturated calcium phosphate rinse; placebo; questionnaire administration; quality-of-life assessment

Esophagectomy, or Esophageal Cancer Clinical Trial using Questionnaires

University of Pittsburgh - Recruiting 18 years or older.
- Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life.
Questionnaires

Prostatic Neoplasms, or Prostate Cancer Clinical Trial

Stanford University - Recruiting 18 years or older.
- Quality of Life Following Radical Prostatectomy.

Breast Cancer Clinical Trial using survey web-based or telephone interview

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years to 64 years.
- Breast Cancer and the Workforce: Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life (BCW).
survey web-based or telephone interview

Female Reproductive Cancer Clinical Trial using mind-body intervention procedure; survey administration; quality-of-life assessment

University of Wisconsin, Madison - Recruiting 18 years or older.
- The Effects of a Media Diversion on Quality of Life in Patients Receiving Chemotherapy for Recurrent Gynecologic Cancers.
mind-body intervention procedure; survey administration; quality-of-life assessment

Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma, C Clinical Trial using quality-of-life assessment; questionnaire administration; cone biopsy; loop electrosurgical excision procedure

Gynecologic Oncology Group - Recruiting 18 years or older.
- Evaluation of Physical Function and Quality of Life (QOL) Before and After Non-Radical Surgical Therapy (Extra Fascial Hysterectomy or Cone Biopsy With Pelvic Lymphadenectomy) for Stage IA1 (LVSI+) and IA2-IB1 (=/<2CM) Cervical Cancer.
quality-of-life assessment; questionnaire administration; cone biopsy; loop electrosurgical excision procedure

Hyponatremia Clinical Trial using Tolvaptan; Placebo; Hepatic Encephalopathy Assessment; Quality of Life Assessment; Vital signs; Blood laboratory tests; Ascites Evaluation; Edema

New York University School of Medicine - Recruiting 18 years or older.
- Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia.
Tolvaptan; Placebo; Hepatic Encephalopathy Assessment; Quality of Life Assessment; Vital signs; Blood laboratory tests; Ascites Evaluation; Edema

Gestational Trophoblastic Tumor, Hydatidiform Mole, Low Risk Meta Clinical Trial using leucovorin calcium; dactinomycin; methotrexate; quality-of-life assessment

Gynecologic Oncology Group - Recruiting 18 years or older.
- A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia.
leucovorin calcium; dactinomycin; methotrexate; quality-of-life assessment

Adenocarcinoma of the Lung, Bronchoalveolar Cell Lung Cancer, Lar Clinical Trial using PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

City of Hope Medical Center - Recruiting 18 years or older.
- Phase I Trial of BKM120 in Combination With Carboplatin and Pemetrexed in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC).
PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

Crohn's Disease Clinical Trial

AbbVie - Recruiting 18 years to 65 years.
- Improvement of Work Productivity and Quality of Life With Anti-TNF Therapies Used in Crohn's Disease in Routine Clinical Practice in Turkey.

Suspected Lung Cancer Clinical Trial using observational study: use of patient questionnaires

Universiteit Antwerpen - Recruiting 18 years or older.
- How Burdensome is the Diagnostic Phase ? Distress and Quality of Life in Patients Suspected of Having a (Serious) Lung Disease.
observational study: use of patient questionnaires

Brenner Tumor, Fallopian Tube Cancer, Ovarian Clear Cell Cystaden Clinical Trial using paclitaxel; docetaxel; carboplatin; bevacizumab; gemcitabine hydrochloride; laboratory biomarker analysis; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination With Bevacizumab (NSC #704865, IND #113912) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. NCI-Supplied Agents: Bevacizumab (NSC #704865, IND #113912).
paclitaxel; docetaxel; carboplatin; bevacizumab; gemcitabine hydrochloride; laboratory biomarker analysis; quality-of-life assessment

Stage II Childhood Hodgkin Lymphoma, Stage III Childhood Hodgkin Clinical Trial using brentuximab vedotin; etoposide; prednisone; doxorubicin; cyclophosphamide; Dacarbazine(R); filgrastim; quality of life assessment; radiation therapy

St. Jude Children's Research Hospital - Recruiting N/A to 18 years.
- Adcetris Substituting Vincristine in the OEPA/COPDac Regimen [Treatment Group 3 (TG3) of Euro-Net C1] With Low Dose Tailored-Field Radiation Therapy for Unfavorable Risk Pediatric Hodgkin Lymphoma.
brentuximab vedotin; etoposide; prednisone; doxorubicin; cyclophosphamide; Dacarbazine(R); filgrastim; quality of life assessment; radiation therapy

Cervical Cancer Clinical Trial using Sonifilan

Asan Medical Center - Recruiting 20 years to 75 years.
- The Impact of Sonifilan on the Quality of Life in Patients With Cervical Cancer.
Sonifilan

Advanced Stage Head and Neck Cancer Clinical Trial using Quality of Life Questionaires & Interview: EORTC QLQ C-30, EORTC QLQ H&N-35, Health Behaviors, Subjective Significance Questionnaire, Qualitative Assessment

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- RECONSTRUCTIVE SURGERY For Head And Neck Cancer Patients: A Prospective Analysis Of Quality Of Life And Symptom Relief.
Quality of Life Questionaires & Interview: EORTC QLQ C-30, EORTC QLQ H&N-35, Health Behaviors, Subjective Significance Questionnaire, Qualitative Assessment

Head and Neck Cancer Clinical Trial using Flexible Fiber-based CO2 Laser, Quality of Life forms; electrocautery resection and quality of life forms

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Flexible Fiber-based CO2 Laser Versus Monopolar Cautery for Resection of Benign, Pre-malignant And Malignant Oral Cavity Lesions: A Single Center Randomized Controlled Trial Assessing Pain and Quality of Life Following Surgery.
Flexible Fiber-based CO2 Laser, Quality of Life forms; electrocautery resection and quality of life forms

Esophageal Cancer, Sleep Disturbance, or Quality of Life Clinical Trial using psychological counseling; prevention of sleep disorders in ICU

University of Padova - Recruiting 18 years or older.
- Quality of Life After Esophagectomy for Cancer - QOLEC1.
psychological counseling; prevention of sleep disorders in ICU

Anorexia, Cachexia, Malignant Neoplasm, or Oral Complications of Clinical Trial using bovine lactoferrin supplement; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study of Bovine Lactoferrin in Cancer Patients Reporting Taste Disturbances While Receiving Chemotherapy.
bovine lactoferrin supplement; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis

Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Clinical Trial using questionnaire administration; quality-of-life assessment; management of therapy complications; exercise intervention

University of Southern California - Recruiting 18 years or older.
- Combined Exercise Program for Early Breast Cancer Survivors.
questionnaire administration; quality-of-life assessment; management of therapy complications; exercise intervention

Esophageal Cancer, or Quality of Life Clinical Trial using nutritional counseling; respirology counseling

University of Padova - Recruiting 18 years or older.
- Quality of Life After Esophagectomy for Cancer - Step 2.
nutritional counseling; respirology counseling

Frontotemporal Dementia, or Alzheimer's Disease Clinical Trial

Norwegian Centre for Ageing and Health - Recruiting N/A to 69 years.
- A Nordic Multicentre Observational Study of Persons With Young Onset Dementia and Their Families - Factors Influencing Quality of Life, Theirs Specific Needs and the Use of Healthcare Resources.

Acromegaly Clinical Trial

Massachusetts General Hospital - Recruiting 18 years to 75 years.
- Effect of Growth Hormone Receptor Antagonism and Somatostatin Analog Administration on Quality of Life.

Knee Joint Pain Clinical Trial using Freedom Total Knee; Total Knee Replacement; Freedom Total Knee System

Maxx Orthopedics Inc - Recruiting 40 years to 80 years.
- A Prospective, Multicenter, Single Arm Adaptive-Design Study to Evaluate the Safety, Functionality, and the Quality of Life of Patients Who Receive the Freedom Total Knee r System.
Freedom Total Knee; Total Knee Replacement; Freedom Total Knee System

Glycogen Storage Disease Type IA, Glycogen Storage Disease Type I Clinical Trial

McGill University Health Center - Recruiting 2 years to 50 years.
- A Comparison of Quality of Sleep and Quality of Life in Patients With Glycogen Storage Disease on Standard and Modified Uncooked Cornstarch.

Recurrent Melanoma, Stage IIIB Melanoma, Stage IIIC Melanoma, or Clinical Trial using ipilimumab; recombinant interferon alfa-2b; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-Risk Melanoma.
ipilimumab; recombinant interferon alfa-2b; quality-of-life assessment

Clinically Localized Prostate Cancer Clinical Trial using Stereotactic Body Radiation Therapy (SBRT)

Georgetown University - Recruiting 18 years or older.
- Quality of Life in Patients With Clinically Localized Prostate Cancer Treated With Stereotactic Body Radiation Therapy (SBRT).
Stereotactic Body Radiation Therapy (SBRT)

Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Pro Clinical Trial using stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

City of Hope Medical Center - Recruiting 19 years or older.
- Stereotactic Body Radiation Therapy to the Prostate Fossa: Phase I Dose Escalation Study.
stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocyti Clinical Trial using ibrutinib; rituximab; bendamustine hydrochloride; laboratory biomarker analysis; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 65 years or older.
- A Randomized Phase III Study of Bendamustine Plus Rituximab Versus Ibrutinib Plus Rituximab Versus Ibrutinib Alone in Untreated Older Patients (ò 65 Years of Age) With Chronic Lymphocytic Leukemia (CLL).
ibrutinib; rituximab; bendamustine hydrochloride; laboratory biomarker analysis; quality-of-life assessment

Prostate Cancer, or Radiation Toxicity Clinical Trial using medical chart review; questionnaire administration; quality-of-life assessment; brachytherapy; radiation therapy

University of California, San Francisco - Recruiting N/A or older.
- Pre-Operative Gleason Score and PSA and Clinical Stage in Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer.
medical chart review; questionnaire administration; quality-of-life assessment; brachytherapy; radiation therapy

Aging Clinical Trial using Home-based, DVD-delivered physical activity; Usual care/Wait list

University of Illinois at Urbana-Champaign - Recruiting 65 years to 85 years.
- Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life.
Home-based, DVD-delivered physical activity; Usual care/Wait list

Lower Extremity Lymphedema, or Endometrial Cancer Clinical Trial

Duke University - Recruiting 18 years or older.
- A Pilot Study of Postoperative Lower-extremity Lymphedema and Quality of Life Among Women Undergoing Endometrial Cancer Staging Surgery.

Tinnitus Clinical Trial using observational research

University of Zurich - Recruiting 18 years or older.
- Research Project About Psychological Strain, Quality of Life and Emotional Awareness in Patients With Tinnitus.
observational research

Quality of Life, or Post ICU Discharge Clinical Trial using Medical, psychological, social

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Multicenter Randomised, Controlled Trial of a Intensive Care Follow -up Programme in Improving Long-term Outcomes of ICU Survivors.
Medical, psychological, social

Breast Cancer Clinical Trial using axillary lymph node dissection; isosulfan blue based lymphatic mapping; quality-of-life assessment; Questionnaire administration

City of Hope Medical Center - Recruiting N/A or older.
- Reducing Extremity Lymphedema Through Axillary Lymphatic Preservation Surgery.
axillary lymph node dissection; isosulfan blue based lymphatic mapping; quality-of-life assessment; Questionnaire administration

Hepatitis C, Chronic Clinical Trial

Hoffmann-La Roche - Recruiting 18 years or older.
- A Prospective, Observational, Multicenter Non-interventional Trial Examining Efficacy of Combination Therapy With PEGASYSr Plus COPEGUSr in Patients With Chronic Hepatitis C, Genotype 2, 3, 1 or 4, Undergoing an Opioid Maintenance-Therapy With Special Focus on Patient Compliance and Quality of Life.

Breast Cancer Clinical Trial using trastuzumab [Herceptin]; Chemotherapy

Hoffmann-La Roche - Recruiting 18 years or older.
- An Open Label, Randomised Phase II Study Assessing Quality of Life Associated With Subcutaneous Trastuzumab Injected Into the Thigh or Upper Arm in Patients With HER2-positive Early Breast Cancer.
trastuzumab [Herceptin]; Chemotherapy

Multiple Sclerosis Clinical Trial using Interferon beta-1b (Betaferon, BAY 86-5046)

Bayer - Recruiting 18 years or older.
- BETASLEEP - SLEEP Quality and Functional Health Status, Fatigue, Comorbidities and Therapeutic Algorithms Among BETAferonr Treated MS Patients.
Interferon beta-1b (Betaferon, BAY 86-5046)

Metastatic Gastrointestinal Carcinoid Tumor, Pulmonary Carcinoid Clinical Trial using pazopanib hydrochloride; placebo; quality-of-life assessment; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Prospective Randomized Phase II Trial of Pazopanib (NSC # 737754, IND 75648) Versus Placebo in Patients With Progressive Carcinoid Tumors.
pazopanib hydrochloride; placebo; quality-of-life assessment; laboratory biomarker analysis

Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Ca Clinical Trial using docetaxel; carboplatin; trastuzumab; pertuzumab; goserelin acetate; therapeutic conventional surgery; whole breast irradiation; quality-of-life assessment; laboratory biomarker analysis; aromatase inhibition therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients With Hormone Receptor-Positive, HER2-Positive, Large Operable and Locally Advanced Breast Cancer Treated With Neoadjuvant Therapy of Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab (TCHP) With or Without Estrogen Deprivation.
docetaxel; carboplatin; trastuzumab; pertuzumab; goserelin acetate; therapeutic conventional surgery; whole breast irradiation; quality-of-life assessment; laboratory biomarker analysis; aromatase inhibition therapy

Prostate Cancer Clinical Trial using questionnaire administration; quality-of-life assessment; image-guided radiation therapy; intensity-modulated radiation therapy; radiation therapy treatment planning/simulation

ICORG- All Ireland Cooperative Oncology Research Group - Recruiting 18 years or older.
- A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0M0 Prostate Cancer.
questionnaire administration; quality-of-life assessment; image-guided radiation therapy; intensity-modulated radiation therapy; radiation therapy treatment planning/simulation

Allergic Rhinitis Clinical Trial

Istanbul University - Recruiting 18 years to 70 years.
- Long Term Follow up in Patients Using Immunotherapy: Efficacy and Impact on Quality of Life.

Tumors Metastatic to Brain, or Unspecified Adult Solid Tumor Clinical Trial using stereotactic radiosurgery; quality-of-life assessment; cognitive assessment

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- Dose Escalation for Larger Brain Metastases: Phase I/II Study.
stereotactic radiosurgery; quality-of-life assessment; cognitive assessment

Tumors Metastatic to Brain Clinical Trial using radiosurgery; therapeutic conventional surgery; quality-of-life assessment

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study.
radiosurgery; therapeutic conventional surgery; quality-of-life assessment

Breast Cancer, Cancer Survivor, Cognitive/Functional Effects, or Clinical Trial using cognitive intervention; questionnaire administration; quality-of-life assessment; blood-oxygen-level-dependent functional magnetic resonance imaging; memory intervention

University of Washington - Recruiting 21 years to 90 years.
- Behavioral and Neural Indices of Cognitive Rehabilitation in Women's Cancer: A Pilot Study..
cognitive intervention; questionnaire administration; quality-of-life assessment; blood-oxygen-level-dependent functional magnetic resonance imaging; memory intervention

Gastro-intestinal Cancer, Lung Cancer, Head and Neck Cancer, or B Clinical Trial using Instructed to read patient education pamphlets

Sunnybrook Health Sciences Centre - Recruiting 18 years or older.
- The Impact of a Patient Education Intervention on Knowledge, Self-efficacy, Symptom Burden, Health Related Quality of Life and Satisfaction With the Experience of Care for Oncology Ambulatory Patients Post Completion of the Edmonton Screening Assessment System.
Instructed to read patient education pamphlets

Breakthrough Cancer Pain Clinical Trial using PecFentr (fentanyl) nasal spray

Archimedes Development Ltd - Recruiting 18 years or older.
- A French, Multicentre, Open-label, Observational Study to Assess Quality of Life and Satisfaction in Subjects Taking PecFentr for the Treatment of Breakthrough Cancer Pain (BTPc).
PecFentr (fentanyl) nasal spray

Ostomy Clinical Trial using Standard; Pre-operative Education; Two-week Post Operative Education

Indiana University - Recruiting 18 years to 90 years.
- A Prospective, Single-Center Study to Assess the Impact of Pre- and Post-Surgical Ostomy Care Education on Patient Outcomes and Quality of Life.
Standard; Pre-operative Education; Two-week Post Operative Education

Sleep Apnea, Obstructive Clinical Trial using Adenotonsillectomy; Observation alone / no intervention

Eastern Virginia Medical School - Recruiting 3 years to 16 years.
- Effect of Adenotonsillectomy on Quality of Life in Children With Mild Obstructive Sleep Apnea.
Adenotonsillectomy; Observation alone / no intervention

Quality of Life Clinical Trial using Exercise Intervention

Universidad Politecnica de Madrid - Recruiting 18 years to 80 years.
- Integrative Exercise and Life Style Intervention Increase Leisure Time Activity in Breast Cancer Patients..
Exercise Intervention

Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III S Clinical Trial using cisplatin; docetaxel; cetuximab; laboratory biomarker analysis; quality-of-life assessment; intensity-modulated radiation therapy

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered With Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck.
cisplatin; docetaxel; cetuximab; laboratory biomarker analysis; quality-of-life assessment; intensity-modulated radiation therapy

Glaucoma, or Quality of Life Clinical Trial

Wills Eye - Recruiting 18 years to 80 years.
- A Prospective, Longitudinal, Observational Cohort Study Examining How Glaucoma Affects Quality of Life and Visual Function Over a 4-Year Period.

Peripheral Artery Disease, Quality of Life, or Wound Healing Clinical Trial using VADOplex system

Asklepios Kliniken Hamburg GmbH - Recruiting 18 years or older.
- Prospektive, Randomisierte Und Kontrollierte Studie Zum Einfluss Des VADOplex-Systems Auf Die Lebensqualit„t im Rahmen Der Behandlung Der Chronisch-kritischen Extremit„tenisch„mie im Stadium IV Nach Fontaine.
VADOplex system

Anxiety Disorder, Depression, Ductal Breast Carcinoma in Situ, Lo Clinical Trial using educational intervention; counseling intervention; psychosocial support for caregiver; questionnaire administration; laboratory biomarker analysis

University of Washington - Recruiting N/A or older.
- Psychoeducation for Spouses/Partners of Women With Breast Cancer.
educational intervention; counseling intervention; psychosocial support for caregiver; questionnaire administration; laboratory biomarker analysis

Bladder Cancer Clinical Trial using quality-of-life assessment; questionnaire administration

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Bladder Cancer Prognosis Programme (Incorporating SELENIB Trial) [QOL].
quality-of-life assessment; questionnaire administration

Colorectal Cancer, Dysgeusia, or Oral Complications of Chemothera Clinical Trial using questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; bovine lactoferrin

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Pilot Study of Bovine Lactoferrin in Patients With Colorectal Carcinoma Receiving Oxaliplatin-Based Chemotherapy and Self-Reported Taste Disturbances.
questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; bovine lactoferrin

Ras-wildtype Colorectal Cancer Clinical Trial using Erythromycin; Doxycycline

AIO-Studien-gGmbH - Recruiting 18 years or older.
- Comparison of Two Preemptive Treatment Strategies of Panitumumab Mediated Skin Toxicity and Assessment of Quality of Life in Patients With Ras-wildtype Colorectal Cancer.
Erythromycin; Doxycycline

Spinal Cord Injuries Clinical Trial

Department of Veterans Affairs - Recruiting 18 years to 89 years.
- Extending Veteran Participation in the Validation of the SCI-QOL/CAT.

Kidney Cancer Clinical Trial using Pazopanib; Temsirolimus; Quality of Life Assessment; Benadryl

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- A Randomized Phase 2 Trial of Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma.
Pazopanib; Temsirolimus; Quality of Life Assessment; Benadryl

Endometriosis Clinical Trial using Visanne (Dienogest, BAY86-5258)

Bayer - Recruiting 18 years or older.
- Study to Characterize Patients Treated With Visanne for Their Endometriosis Under Real-life Practice Conditions and Evaluate Their Quality of Life at Baseline and After 6 Months of Treatment With Visanne..
Visanne (Dienogest, BAY86-5258)

Anorectal Malformation Clinical Trial using Quality of life questionnaire

Nantes University Hospital - Recruiting 6 years to 30 years.
- National Study on the Quality of Life of Patients With Anorectal Malformation (MARQOL).
Quality of life questionnaire

Adult Spinal Cord Neoplasm, Recurrent Adult Spinal Cord Neoplasm, Clinical Trial using therapeutic conventional surgery; quality-of-life assessment

City of Hope Medical Center - Recruiting 18 years or older.
- Comparison of Minimally Invasive Approaches of Spine Tumor Surgery.
therapeutic conventional surgery; quality-of-life assessment

Hematopoietic/Lymphoid Cancer, or Unspecified Adult Solid Tumor, Clinical Trial using questionnaire administration; quality-of-life assessment

City of Hope Medical Center - Recruiting 18 years or older.
- Physical, Emotional and Social Stressors and Their Impact on Quality of Life of Caregivers of Hospitalized Older Adults With Cancer.
questionnaire administration; quality-of-life assessment

Anal Cancer, HIV Infection, or Human Papilloma Virus Infection Clinical Trial using comparison of screening methods; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

AIDS Malignancy Clinical Trials Consortium - Recruiting 18 years or older.
- Screening HIV-Infected Women for Anal Cancer Precursors.
comparison of screening methods; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

Parkinson's Disease Clinical Trial

AbbVie - Recruiting 18 years or older.
- Analysis of MOtor and NOn Motor Symptoms, Quality of Life and Occurence of Dyskinesias in Advanced Parkinson's Disease Patients With 2 to 4 Hours 'Off-time' and Without Troublesome Dyskinesias Under Duodopa TREATment - a Multi-country Post-marketing Observational Study -MONOTREAT.

Tobacco Use Disorder Clinical Trial using smoking cessation intervention; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; ecigarettes

Roswell Park Cancer Institute - Recruiting 18 years or older.
- Exploring Current Smokers' Interest in Using Smokeless Tobacco Products Smokeless Tobacco Substitution for Cigarettes.
smoking cessation intervention; questionnaire administration; quality-of-life assessment; laboratory biomarker analysis; ecigarettes

Quality of Life, Chronic Disease, or Chronic Illness Clinical Trial using Med Complex Children Intervention

Seton Family of Hospitals - Recruiting N/A to 17 years.
- Comprehensive Care of Children With Medical Complexity: Piloting an Innovative Model.
Med Complex Children Intervention

Squamous Cell Carcinoma of the Oropharynx Clinical Trial using questionnaire and semi-structured interviews

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- Surviving Oropharynx Cancer: Long-Term Impact of Human Papillomavirus (HPV) on Quality of Life.
questionnaire and semi-structured interviews

Nonsmall Cell Lung Cancer Cellular Diagnosis Clinical Trial using Anterolateral thoracotomy; Posterolateral thoracotomy; VATS; Anterolateral Thoracotomy

Odense University Hospital - Recruiting 18 years or older.
- Minimally Invasive or Open Surgery for Lung Cancer: Pain, Quality of Life and Economy..
Anterolateral thoracotomy; Posterolateral thoracotomy; VATS; Anterolateral Thoracotomy

Recurrent Non-small Cell Lung Cancer, Stage IIIA Non-small Cell L Clinical Trial using therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Pilot Study of Stereotactic Body Radiation Therapy (SBRT) After TEMLA for Stage III and IV (Oligometastatic) Non-Small Cell Lung Cancer.
therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Adult Acute Erythroid Leukemia (M6), Adult Acute Megakaryoblastic Clinical Trial using asparaginase; daunorubicin hydrochloride; mitoxantrone hydrochloride; sorafenib tosylate; cytarabine; etoposide; bortezomib; pharmacological study; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A to 29 years.
- A Phase III Randomized Trial for Patients With de Novo AML Using Bortezomib and Sorafenib (IND#114480; NSC# 681239, NSC# 724772) for Patients With High Allelic Ratio FLT3/ITD.
asparaginase; daunorubicin hydrochloride; mitoxantrone hydrochloride; sorafenib tosylate; cytarabine; etoposide; bortezomib; pharmacological study; laboratory biomarker analysis; questionnaire administration; quality-of-life assessment

Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmo Clinical Trial using Life Completion; Attention Control

Department of Veterans Affairs - Recruiting 18 years or older.
- Outlook: An Intervention to Improve Quality of Life in Serious Illness Study.
Life Completion; Attention Control

Oropharyngeal Squamous Cell Carcinoma, or Supraglottic Squamous C Clinical Trial using Transoral robotic surgery

University of Virginia - Recruiting 18 years or older.
- A Single Arm Study of Efficacy and Functional Quality of Life in Patients Treated With Transoral Robotic Surgery for Oropharyngeal and Supraglottic Squamous Cell Carcinoma.
Transoral robotic surgery

Asthma Clinical Trial using Exercise

University of Oulu - Recruiting 16 years to 65 years.
- Effects of Regular Exercise on Physical Fitness, Asthma Control and Quality of Life of Adult Asthmatics.
Exercise

Total Exenteration,, Anterior or Posterior Pelvic Exenteration, G Clinical Trial using questionnaires/interviews

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Prospective Study of Quality of Life in Patients Undergoing Pelvic Exenteration.
questionnaires/interviews

Rectal Cancer Clinical Trial using Questionnaire

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Pilot Study for Prospective Discovery of Possible Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations in Patients Undergoing Treatment for Locally Recurrent Rectal Adenocarcinoma.
Questionnaire

Metastatic Cancer, or Unspecified Adult Solid Tumor, Protocol Spe Clinical Trial using bevacizumab; quality-of-life assessment

Northwestern University - Recruiting 18 years or older.
- A Phase II Trial of Bevacizumab in Patients With Recurrent Solid Tumor Brain Metastases Who Have Failed Whole Brain Radiation Therapy.
bevacizumab; quality-of-life assessment

Major Depression Clinical Trial using Deep Brain Stimulation with Activa PC Multi-program Neurostimulator

University Hospital, Bonn - Recruiting 20 years to 75 years.
- Assessment of Efficacy, Safety and Effects on Quality of Life of Deep Brain Stimulation to the Medial Forebrain Bundle in Patients With Treatment Resistant Major Depression (FORESEE II: FOREbrain Stimulation dEprEssion).
Deep Brain Stimulation with Activa PC Multi-program Neurostimulator

Breast Cancer Clinical Trial

City of Hope Medical Center - Recruiting 18 years or older.
- Adjuvant Therapy in Older Versus Younger Women With Breast Cancer: Longitudinal Impact of Adjuvant Chemotherapy on Functional Status, Comorbidity and Quality of Life.

Carcinoma of the Appendix, or Primary Peritoneal Cavity Cancer Clinical Trial using mitomycin C; oxaliplatin; therapeutic conventional surgery; quality-of-life assessment; hyperthermic intraperitoneal chemotherapy

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- A Multi-Center, Open-Label, Randomized Phase II Trial to Evaluate Hematologic Toxicities After HIPEC With Oxaliplatin or Mitomycin C in Patients With Appendiceal Tumors.
mitomycin C; oxaliplatin; therapeutic conventional surgery; quality-of-life assessment; hyperthermic intraperitoneal chemotherapy

Stage I Squamous Cell Carcinoma of the Oropharynx, Stage II Squam Clinical Trial using questionnaire administration; quality-of-life assessment

University of Chicago - Recruiting 18 years or older.
- Patient Preferences in Head and Neck Cancer Treatment Decisions - a Pilot Study of the Durability of Patient Priorities.
questionnaire administration; quality-of-life assessment

Prostate Cancer, Erectile Dysfunction Following Radical Prostatec Clinical Trial using Intensive Fitness Intervention; TRIMM

Johns Hopkins University - Recruiting 40 years to 65 years.
- Health Interventions in Men Undergoing Radical Prostatectomy- A Randomized Controlled Clinical Trial.
Intensive Fitness Intervention; TRIMM

Cancer Survivor, Depression, or Hematopoietic/Lymphoid Cancer Clinical Trial using questionnaire administration; survey administration; quality-of-life assessment; internet-based intervention

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- INSPIRE for Survivorship After Transplant: A Multicenter Randomized Controlled Trial of an Internet and Social-media Program for Long-term Hematopoietic Cell Transplantation Survivors.
questionnaire administration; survey administration; quality-of-life assessment; internet-based intervention

Systemic Scleroderma, or Severe Systemic Sclerosis Clinical Trial using fludarabine phosphate; Mycophenolic Acid; tacrolimus; total-body irradiation; bone marrow transplantation; reduced intensity allogeneic hematopoietic stem cell transplantation; quality-of-life assessment; laboratory biomarker analysis; flow cytometry; biopsy; cyclophosphamide

Fred Hutchinson Cancer Research Center - Recruiting N/A to 70 years.
- Allogeneic Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning for Patients With Severe Systemic Sclerosis.
fludarabine phosphate; Mycophenolic Acid; tacrolimus; total-body irradiation; bone marrow transplantation; reduced intensity allogeneic hematopoietic stem cell transplantation; quality-of-life assessment; laboratory biomarker analysis; flow cytometry; biopsy; cyclophosphamide

Mechanical Complication of Coronary Artery Bypass Graft, Respirat Clinical Trial using Usual care; Osteopathic treatment

Hartcentrum Hasselt - Recruiting N/A or older.
- Effect of Osteopathy on Pulmonary Function in Patients After Coronary Artery Bypass Graft Surgery: a Randomized Controlled Trial.
Usual care; Osteopathic treatment

Breast Cancer, Cancer Survivor, Fatigue, or Psychosocial Effects Clinical Trial using protein analysis; laboratory biomarker analysis; mass spectrometry; questionnaire administration; assessment of therapy complications; cognitive assessment; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- Biological Mechanisms of Fatigue in Breast Cancer Survivors.
protein analysis; laboratory biomarker analysis; mass spectrometry; questionnaire administration; assessment of therapy complications; cognitive assessment; quality-of-life assessment

Prostate Cancer, or Sexual Dysfunction Clinical Trial using laboratory biomarker analysis; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- HIFU Lesion Control in Patients With Non-metastatic Progressive Prostate Cancer.
laboratory biomarker analysis; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

Chemotherapeutic Agent Toxicity, Lymphoma, Mucositis, or Neurotox Clinical Trial using glucarpidase; leucovorin calcium; methotrexate; laboratory biomarker analysis; quality-of-life assessment; radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase I Trial of Escalating High Dose Methotrexate Supported by Glucarpidase to Treat Patients With Primary Central Nervous Lymphoma (PCNSL).
glucarpidase; leucovorin calcium; methotrexate; laboratory biomarker analysis; quality-of-life assessment; radiation therapy

Prostate Cancer Clinical Trial using gonadotrophin releasing hormone; cyproterone acetate; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A to 79 years.
- Intermittent Hormone Therapy for Newly Diagnosed Metastatic Prostate Cancer.
gonadotrophin releasing hormone; cyproterone acetate; quality-of-life assessment

Prostate Cancer Clinical Trial using pharmacological study; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- An Evaluation of Lesion Control Using Focal Ablation With High Intensity Focused Ultrasound in the Treatment of Non-Metastatic Progressive Prostate Cancer.
pharmacological study; questionnaire administration; assessment of therapy complications; high-intensity focused ultrasound ablation; quality-of-life assessment

Cirrhosis, Hepatic Encephalopathy, Diuretic-Resistant Refractory Clinical Trial using Large Volume Paracentesis

New York University School of Medicine - Recruiting 18 years to 75 years.
- The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis.
Large Volume Paracentesis

Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage Clinical Trial using stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Case Comprehensive Cancer Center - Recruiting 18 years or older.
- High-Dose Stereotactic Body Radiation Therapy in Treating Patients With Low-, Intermediate-, or High-Risk Localized Prostate Cancer.
stereotactic body radiation therapy; quality-of-life assessment; laboratory biomarker analysis

Multiple Myeloma and Plasma Cell Neoplasm Clinical Trial using clonality analysis; polymerase chain reaction; protein analysis; biologic sample preservation procedure; laboratory biomarker analysis; fluorescence spectroscopy; quality-of-life assessment

Boston Medical Center - Recruiting 18 years or older.
- Data, Tissue, Blood, and Urine Repository for Amyloid Diseases.
clonality analysis; polymerase chain reaction; protein analysis; biologic sample preservation procedure; laboratory biomarker analysis; fluorescence spectroscopy; quality-of-life assessment

Prostate Cancer Clinical Trial using exercise intervention; nutritional supplementation; quality-of-life assessment; questionnaire administration; pharmacological study; laboratory biomarker analysis

USC/Norris Comprehensive Cancer Center - Recruiting 50 years or older.
- Exercise and Whey Protein Supplementation as Adjunctive Therapy for Patients With Prostate Cancer Receiving Androgen Deprivation Therapy.
exercise intervention; nutritional supplementation; quality-of-life assessment; questionnaire administration; pharmacological study; laboratory biomarker analysis

Crohn's Disease Clinical Trial using Elimination Diet; Dietary Guidelines for Americans

Johns Hopkins University - Recruiting 18 years to 75 years.
- The Relationship of a 'Crohn's Disease Diet' in Reducing Symptoms of Crohn's Disease, Improving Quality of Life, and Decreasing Related Health Care Costs..
Elimination Diet; Dietary Guidelines for Americans

Morbid Obesity, Diabetes, or Hypertension Clinical Trial

Assuta Hospital Systems - Recruiting 14 years to 65 years.
- A Prospective Trial for Laparoscopic Adjustable Gastric Banding in Morbidly Obese Patients: Report on Weight Loss, Metabolic Changes and Quality of Life.

Epilepsy Clinical Trial using Enhanced walking program

Children's Hospital of Eastern Ontario - Recruiting 8 years to 14 years.
- Enhancing Physical Activity in Children With Epilepsy: Impacts on Health and Quality of Life.
Enhanced walking program

Local Tumor Spread, Advanced Cancer, Metastasized, Pancreatic Can Clinical Trial using Stent; Biliodigestive anastomosis

Universit„tsklinikum Hamburg-Eppendorf - Recruiting 18 years to 90 years.
- Quality of Life After Bilioenteric Anastomosis in Comparison to Endoscopically Placed Stents in Patients With Unresectable Pancreatic Cancer and Jaundice.
Stent; Biliodigestive anastomosis

Needs for Rehabilitation, Adult Attachment Style, Quality of Life Clinical Trial using Rehabilitation goals of patients with gynaecological cancer.

Odense University Hospital - Recruiting 20 years to 75 years.
- Rehabilitation and the Association With Attachment Styles Among Patients With Gynaecological Cancer.
Rehabilitation goals of patients with gynaecological cancer.

Osteoporosis Clinical Trial using Melatonin

University of Aarhus - Recruiting 55 years to 75 years.
- Treatment of Osteopenia With Melatonin: Effects on BMD, Muscle Strength and Quality of Life.
Melatonin

Breast Cancer, or Cancer Survivor Clinical Trial using internet-based intervention; management of therapy complications; educational intervention; questionnaire administration; quality-of-life assessment

University of Wisconsin, Madison - Recruiting 25 years to 64 years.
- Reducing Work Disability in Breast Cancer Survivors.
internet-based intervention; management of therapy complications; educational intervention; questionnaire administration; quality-of-life assessment

Primary Non-operated Squamous Cell Carcinoma of Oral Cavity, Prim Clinical Trial using video fluoroscopy; extra imaging; scoring acute toxicity; scoring of late toxicity; scoring quality of life (QOL)

University Hospital, Ghent - Recruiting 18 years or older.
- Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck: a Multicenter, Two-arm, Randomized Phase II Trial..
video fluoroscopy; extra imaging; scoring acute toxicity; scoring of late toxicity; scoring quality of life (QOL)

Physical Activity, Blood Pressure, Physical Functioning, Quality Clinical Trial using Physical Activity; Group educational sessions; Phone counseling call; Peer Mentoring; Policy Change; Psychosocial support; Tailored environmental resources; Group educational lectures; Health check phone call; Pedometer

University of California, San Diego - Recruiting 65 years or older.
- MIPARC - Multilevel Intervention for Physical Activity in Retirement Communities.
Physical Activity; Group educational sessions; Phone counseling call; Peer Mentoring; Policy Change; Psychosocial support; Tailored environmental resources; Group educational lectures; Health check phone call; Pedometer

Rectal Neoplasm Clinical Trial using Hand-sewn coloanal anastomosis; Two staged Turnbull-Cutait procedure; Ultralow anterior rectal resection with total mesorectal excision

Hospital Universitari de Bellvitge - Recruiting 18 years to 74 years.
- Prospective Multicenter Randomized Controlled Trial Comparing Postoperative Complications and Quality of Life in Low Rectal Cancer Surgery Between Coloanal Anastomosis and Lateral Ileostomy Versus Two-Stage Turnbull-Cutait Coloanal Anastomosis.
Hand-sewn coloanal anastomosis; Two staged Turnbull-Cutait procedure; Ultralow anterior rectal resection with total mesorectal excision

Endometrial Cancer, or Treatment by Robotic Assisted Laparoscopy Clinical Trial

Copenhagen University Hospital at Herlev - Recruiting N/A or older.
- Robot-assisted Laparoscopic Hysterectomy-RALH- Postoperative Complications, Quality of Life and Health Economics.

Quality of Life, Pelvic Floor Distress and Impact Scores, or Sexu Clinical Trial using Physical therapy

TriHealth Inc. - Recruiting 18 years to 80 years.
- Effects of Physical Therapy on Quality of Life and Function Following Vaginal Reconstructive Surgery; a Randomized Trial.
Physical therapy

Breast Cancer Clinical Trial using letrozole; laboratory biomarker analysis; questionnaire administration; breast imaging study; dynamic contrast-enhanced magnetic resonance imaging; neoadjuvant therapy; quality-of-life assessment; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Study of Neoadjuvant Letrozole for Postmenopausal Women With Estrogen Receptor Positive Ductal Carcinoma In SITU (DCIS).
letrozole; laboratory biomarker analysis; questionnaire administration; breast imaging study; dynamic contrast-enhanced magnetic resonance imaging; neoadjuvant therapy; quality-of-life assessment; therapeutic conventional surgery

Kidney Failure, Chronic Clinical Trial using Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.

Consorzio Mario Negri Sud - Recruiting 18 years or older.
- Effects of the Dose of Erythropoiesis Stimulating Agents on Cardiac-cerebrovascular Outcomes Quality of Life and Costs in Hemodialysis Patients. The Clinical Evaluation of the DOSe of Erythropoietins (C.E. DOSE) Trial.
Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.

Hypertension, Pulmonary, or Pulmonary Disease, Chronic Obstructiv Clinical Trial

Wissenschaftliches Institut Bethanien e.V - Recruiting 18 years or older.
- Chronisch Obstruktive Lungenerkrankung Und Pulmonale Hypertonie: Pr„valenz Und Lebensqualit„t.

Pain, Postoperative Clinical Trial using Minimally invasive repair of pectus excavatum; Open surgical repair of pectus carinatum

University of Aarhus - Recruiting 7 years or older.
- Short and Long-term Effects of Surgical Repair of Pectus Excavatum and Pectus Carinatum - A Questionnaire Study of Persistent Post-surgical Pain, Health-related Quality of Life, Patient Satisfaction, and Aesthetic Outcome.
Minimally invasive repair of pectus excavatum; Open surgical repair of pectus carinatum

Breast Cancer, or Cancer-related Fatigue Clinical Trial using Supervised progressive resistance training; Supervised progressive muscle relaxation training (Jacobsen method)

German Cancer Research Center - Recruiting 18 years or older.
- Progressive Resistance Training vs. Relaxation for Breast Cancer Patients During Chemotherapy: A Randomized Controlled Intervention Trial to Evaluate the Biological Mechanisms and Effects of Resistance Training on Fatigue and Quality of Life.
Supervised progressive resistance training; Supervised progressive muscle relaxation training (Jacobsen method)

Pulmonary Arterial Hypertension, or Eisenmenger Syndrome Clinical Trial using respiratory and exercise therapy

University of Heidelberg - Recruiting 18 years to 80 years.
- Influence of Respiratory and Exercise Therapy on Oxygen Uptake, Quality of Life in Patients With Severe Associated Pulmonary Arterial Hypertension (APAH) as Part of a Congenital Heart Defect With / Without Eisenmenger's Syndrome.
respiratory and exercise therapy

Advanced Cancer Clinical Trial using Quality Of Life questionnaires completion

ICO Paul Papin - Recruiting 18 years or older.
- Evaluation and Validation of Quality Of Life Scales in Palliative Advanced Cancer.
Quality Of Life questionnaires completion

Cognitive/Functional Effects, Fallopian Tube Cancer, Ovarian Canc Clinical Trial using systemic chemotherapy; questionnaire administration; assessment of therapy complications; cognitive assessment; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Prospective Study of Cognitive Function During Chemotherapy for Front-Line Treatment of Ovarian, Primary Peritoneal or Fallopian Tube Cancer.
systemic chemotherapy; questionnaire administration; assessment of therapy complications; cognitive assessment; quality-of-life assessment

Esophageal Cancer, or Gastro-esophageal Junction Cancer Clinical Trial using Home visits; standard

Odense University Hospital - Recruiting 18 years or older.
- Prospective, Randomized Trial of the Effects on HRQoL, Cost-Utility and Reintervention Rate, of Nurse Home Visits, in Patients With SEMS Treated Malignant Disease in the Esophagus and Cardia..
Home visits; standard

Parkinson's Disease Clinical Trial

Washington University School of Medicine - Recruiting 40 years to 70 years.
- Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in PD Without Dementia.

Brain and Central Nervous System Tumors Clinical Trial using temozolomide; DNA methylation analysis; laboratory biomarker analysis; adjuvant therapy; quality-of-life assessment; radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial..
temozolomide; DNA methylation analysis; laboratory biomarker analysis; adjuvant therapy; quality-of-life assessment; radiation therapy

Lung Cancer, or Thromboembolism Clinical Trial using dalteparin; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- FRAGMATIC - A Randomised Phase III Clinical Trial Investigating the Effect of FRAGMin Added to Standard Therapy In Patients With Lung Cancer.
dalteparin; quality-of-life assessment

Colorectal Cancer Clinical Trial using laboratory biomarker analysis; computed tomography; magnetic resonance imaging; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 50 years or older.
- A Randomised Controlled Trial to Assess the Cost-effectiveness of Intensive Versus no Scheduled Follow-up in Patients Who Have Undergone Resection for Colorectal Cancer With Curative Intent. (FACS - Follow-up After Colorectal Surgery).
laboratory biomarker analysis; computed tomography; magnetic resonance imaging; quality-of-life assessment

Breast Cancer, or Precancerous Condition Clinical Trial using medical chart review; questionnaire administration; study of socioeconomic and demographic variables; Excess human biological tissue; quality-of-life assessment

University of Nebraska - Recruiting 19 years or older.
- Development and Implementation of The Breast Cancer Collaborative Registry (BCCR).
medical chart review; questionnaire administration; study of socioeconomic and demographic variables; Excess human biological tissue; quality-of-life assessment

Retinoblastoma Clinical Trial

Hadassah Medical Organization - Recruiting 1 year to 18 years.
- Quality of Life in Children Cured of Retinoblastoma.

Heart Failure Clinical Trial using Supervised progressive exercise program with an aerobic and a strength component + Optimized treatment; Optimized treatment according to the European Society of Cardiology guidelines

Basque Health Service - Recruiting 18 years or older.
- Rationale and Design of a Randomised Controlled Trial Evaluating the Effectiveness of an Exercise Program to Improve the Quality of Life of Patients With Heart Failure in Primary Care: The EFICAR Study Protocol.
Supervised progressive exercise program with an aerobic and a strength component + Optimized treatment; Optimized treatment according to the European Society of Cardiology guidelines

Oesophageal Cancer Clinical Trial using gastric tube

Peking University - Recruiting 30 years to 75 years.
- The Effects of Gastric Tube on the Quality of Life and Nutritional Status After Ivor-Lewis Esophagectomy: A Randomized Control Trial and Physiological Study.
gastric tube

Prostate Cancer Clinical Trial using counseling intervention; educational intervention; quality-of-life assessment; therapeutic conventional surgery; iodine I 125; palladium Pd 103

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Surgery and Brachytherapy: A Randomized Evaluation. Randomized Controlled Trial of Brachytherapy Versus Radical Prostatectomy in Good Risk Prostate Cancer: A Feasibility Study.
counseling intervention; educational intervention; quality-of-life assessment; therapeutic conventional surgery; iodine I 125; palladium Pd 103

Breast Cancer Clinical Trial using quality-of-life assessment; therapeutic conventional surgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Multicenter (Phase II) Study of Oncoplastic Surgical Techniques for Breast Conservation in Breast Cancers.
quality-of-life assessment; therapeutic conventional surgery

Breast Cancer, Depression, Long-term Effects of Cancer Treatment, Clinical Trial using educational intervention; informational intervention; internet-based intervention; questionnaire administration; study of socioeconomic and demographic variables; survey administration; psychosocial assessment and care; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting N/A or older.
- Cancer Information Service Research Consortium: Years 2006-2011 Program Narrative and Overview.
educational intervention; informational intervention; internet-based intervention; questionnaire administration; study of socioeconomic and demographic variables; survey administration; psychosocial assessment and care; quality-of-life assessment

Contraception After First Trimester Abortion Clinical Trial using Post-abortal provision of intrauterine device

Helsinki University Central Hospital - Recruiting 18 years or older.
- Systematic Provision of Intrauterine Contraception After First Trimester Abortion - Effects on Quality of Life and Risk of Repeat Abortion. A Randomized, Prospective Trial..
Post-abortal provision of intrauterine device

Head and Neck Cancer, Ototoxicity, or Radiation Toxicity Clinical Trial using adjuvant therapy; assessment of therapy complications; quality-of-life assessment; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Multicenter Randomized Study of Cochlear Sparing Intensity Modulated Radiotherapy Versus Conventional Radiotherapy in Patients With Parotid Tumors.
adjuvant therapy; assessment of therapy complications; quality-of-life assessment; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

Alcohol Dependence Clinical Trial using Baclofen (as add-on to standard treatment of alcohol dependence)

Sha'ar Menashe Mental Health Center - Recruiting 18 years to 64 years.
- Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients and Its Effect on Quality of Life, Clinical and Psychosocial Features: A 12-Week Double-Blind Randomized Controlled Trial.
Baclofen (as add-on to standard treatment of alcohol dependence)

Pancreatic Cancer Clinical Trial using efavirenz; quality-of-life assessment

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Trial to Assess the Efficacy of Efavirenz as Second-line Monotherapy for the Treatment of Advanced Pancreatic Adenocarcinomas..
efavirenz; quality-of-life assessment

Lung Cancer Clinical Trial using Nutritional Assessment; EPA-DHA arm

National Institute of Cancerolog¡a - Recruiting 20 years to 75 years.
- A Prospective Randomized Trial: Effect of Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)- Containing Supplement on the Nutritional and Inflammatory Status, Quality of Life, Toxicity and Response Rate to First-line Chemotherapy in Patients With Advanced Lung Cancer.
Nutritional Assessment; EPA-DHA arm

Lung Cancer Clinical Trial using cisplatin; docetaxel; quality-of-life assessment; radiation therapy; stereotactic radiosurgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Study of Doses Escalation on Efficacy on Cyberknife After Docetaxel-Cisplatin Concomitant Radiotherapy for Non Small Cells Lung Cancer Stage III.
cisplatin; docetaxel; quality-of-life assessment; radiation therapy; stereotactic radiosurgery

Colorectal Cancer Clinical Trial using FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Open- Labeled, Prospective Study to Determine the Efficacy of Pre- Operative Chemotherapy With Six Cycles of Modified FOLFOX 6 Followed by Total Mesorectal Excision (TME) Followed by an Additional Six Cycles of FOLFOX 6.
FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

Esophageal Cancer Clinical Trial using Prosure; Ensure Plus

University of Dublin, Trinity College - Recruiting 18 years to 80 years.
- Randomized Double Blinded Trial to Investigate Effects of an Enteral Nutritional Supplement Enriched With Eicosapentaenoic Acid on Body Composition,Complications,Stress Response,Immune Function & Quality of Life in After Esophagectomy.
Prosure; Ensure Plus

Lower Limb Length Discrepancy, or Lower Limb Angular Deformity Clinical Trial using Botulinum toxin A injection; saline injection

Shriners Hospitals for Children - Recruiting 5 years to 21 years.
- Safety and Efficacy of Botox Injection in Alleviating Post-Operative Pain and Improving Quality of Life in Lower Extremity Limb Lengthening and Deformity Correction.
Botulinum toxin A injection; saline injection

Cancer, or Quality of Life Clinical Trial

Johann Wolfgang Goethe University Hospitals - Recruiting N/A or older.
- Analysis of Palliative Surgery in View of Quality of Life and Prognosis.

Atrial Fibrillation Clinical Trial using Exercise

University of Texas Southwestern Medical Center - Recruiting N/A or older.
- The Effect of Low Intensity Exercise on Quality of Life and Hemodynamics in Patients With Permanent Atrial Fibrillation.
Exercise

Arrhythmia, Quality of Life, or Hypomagnesemia Clinical Trial using Magnesium L-lactate

Hartford Hospital - Recruiting 18 years or older.
- The Adjuvant Magnesium Trial (AdMag): Assessment if the Impact of Oral Magnesium on ICD Firing and Quality of Life.
Magnesium L-lactate

Leiomyoma, or Adenomyosis Clinical Trial using questionnaires

National Taiwan University Hospital - Recruiting 21 years to 80 years.
- Health-Related Quality of Life Among Women Receiving Hysterectomy in National Taiwan University Hospital.
questionnaires