51 results found.

Rectal Cancer Clinical Trial using nitroglycerin

University of Texas Southwestern Medical Center - Recruiting 18 years to 90 years.
- Phase I Dose Escalation Trial of Nitroglycerin in Addition to 5-flourouracil and Radiation Therapy for Neo-adjuvant Treatment of Operable Rectal Cancer.
nitroglycerin

Average-risk Patients for Colon Cancer Clinical Trial using Stool DNA Test; biopsies of rectal and colon mucosa; Questionnaires

Case Comprehensive Cancer Center - Recruiting 30 years to 80 years.
- Screening and Risk Factors of Colon Neoplasia.
Stool DNA Test; biopsies of rectal and colon mucosa; Questionnaires

Rectal Cancer Clinical Trial

Uppsala University - Recruiting 18 years or older.
- IPC Status as a Surgical Quality Marker in Rectal Cancer Surgery.

Rectal Cancer Clinical Trial using folfox; short course Radiotherapy

Yonsei University - Recruiting 18 years or older.
- A Phase 2 Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis.
folfox; short course Radiotherapy

Rectal Cancer Clinical Trial using Surgery after 11 weeks of delay after chemoradiotherapy.; Surgery after 7 weeks of delay after chemoradiotherapy

Assistance Publique - Hôpitaux de Paris - Recruiting 18 years or older.
- Randomized Control Trial Comparing the Impact of a Lengthening of the Interval Between the Radiochemotherapy and Surgery (7 Weeks vs. 11 Weeks) on Complete Pathological Response in Rectal Cancer.
Surgery after 11 weeks of delay after chemoradiotherapy.; Surgery after 7 weeks of delay after chemoradiotherapy

Rectal Cancer Clinical Trial using Advanced MR Imaging

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- Pilot Study of Advanced MR Imaging for Early Biologic Tumor Changes to Neoadjuvant Chemoradiation Treatment for Rectal Cancer.
Advanced MR Imaging

Colorectal Cancer Clinical Trial using Early urinary catheter removal

Stanford University - Recruiting 18 years or older.
- Early Removal of Urinary Catheters in Patients After Rectal Surgery: a Prospective Study.
Early urinary catheter removal

Postoperative Ileus Clinical Trial using Electroacupuncture

Chinese University of Hong Kong - Recruiting 18 years to 80 years.
- Can Electroacupuncture Prevent Prolonged Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer? A Prospective Study With Matched Historical Controls.
Electroacupuncture

Advanced Rectal Cancer Clinical Trial using Induction and gap chemotherapy (Capecitabine combine with oxaliplatin); standard chemoradiotherapy

Sun Yat-sen University - Recruiting 18 years to 70 years.
- Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.
Induction and gap chemotherapy (Capecitabine combine with oxaliplatin); standard chemoradiotherapy

Rectal Cancer Clinical Trial using blood sampels from vena rectalis superior and vena cubiti

Odense University Hospital - Recruiting 18 years or older.
- .
blood sampels from vena rectalis superior and vena cubiti

Rectal Cancer Clinical Trial using LifeSealT Kit

LifeBond Ltd. - Recruiting 18 years to 90 years.
- LifeSealT Pilot Study in Subjects Undergoing Circular Stapled Anastomosis Created Within 10 cm of the Anal Verge.
LifeSealT Kit

Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Clinical Trial using ziv-aflibercept; leucovorin calcium; irinotecan hydrochloride; fluorouracil

City of Hope Medical Center - Recruiting 18 years or older.
- A Prospective Study of Short Infusion of Ziv-Aflibercept in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer.
ziv-aflibercept; leucovorin calcium; irinotecan hydrochloride; fluorouracil

Metastatic Colorectal Cancer, Colon Cancer, or Rectal Cancer Clinical Trial using IMMU-130

Immunomedics, Inc. - Recruiting 18 years or older.
- A Phase I/II Study of Once or Twice Weekly IMMU-130 (hMN-14-SN38, Antibody-Drug Conjugate) in Patients With Colorectal Cancer..
IMMU-130

Rectal Cancer Clinical Trial using CRLX101; Capecitabine; Radiotherapy; Surgery

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- Phase Ib/II Study of Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Locally Advanced Rectal Cancer.
CRLX101; Capecitabine; Radiotherapy; Surgery

Rectal Cancer Clinical Trial using conventional ELAPE; Individual ELAPE

Beijing Chao Yang Hospital - Recruiting 18 years to 80 years.
- Randomized Clinical Trial of Conventional Versus Individual Extralevator Abdominoperineal Excision for Locally Advanced Lower Rectal Cancer.
conventional ELAPE; Individual ELAPE

Rectal Cancer Clinical Trial using Sorafenib; 5-Fluorouracil (5-FU); Radiation

H. Lee Moffitt Cancer Center and Research Institute - Recruiting 18 years or older.
- Phase I Study of Pre-operative Continuous 5-FU, and Sorafenib With External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma.
Sorafenib; 5-Fluorouracil (5-FU); Radiation

Rectal Cancer Clinical Trial using M1 scheme; standard long course chemoradiotherapy

University Medical Centre Groningen - Recruiting 18 years or older.
- Randomized Multicentre Phase III Study of Short Course Radiation Therapy Followed by Prolonged Pre-operative Chemotherapy and Surgery in Primary High Risk Rectal Cancer Compared to Standard Chemoradiotherapy and Surgery and Optional Adjuvant Chemotherapy..
M1 scheme; standard long course chemoradiotherapy

Colorectal Cancer Clinical Trial using 5 cm colon-J-pouch; side-to-end anastomosis; straight coloanal anastomosis

Swiss Group for Clinical Cancer Research - Recruiting 18 years or older.
- Clinical Function After Total Mesorectal Excision and Rectal Replacement. A Prospective Randomized Trial Comparing Side-to-End Anastomosis, Colon-J-Pouch and Straight Coloanal Anastomosis.
5 cm colon-J-pouch; side-to-end anastomosis; straight coloanal anastomosis

Rectal Cancer Clinical Trial using Radiation

AHS Cancer Control Alberta - Recruiting 18 years or older.
- A Feasibility Study to Compare the Benefits of Endoscopic Tumor Clip Placement and 3T-MRI Simulation for Accurate Target Volume Definition for Rectal Cancer Patients Undergoing Pre-operative Chemoradiation.
Radiation

Rectal Cancer Clinical Trial using fluorouracil; fluorouracil, oxaliplatin

Sun Yat-sen University - Recruiting 18 years to 75 years.
- A Phase II/III Randomized Controlled Study of Neoadjuvant FOLFOX6 Treatment With or Without Radiation Compared to 5-Fu Based Chemoradiation in Treating Patients With Resectable Rectal Cancer.
fluorouracil; fluorouracil, oxaliplatin

Rectal Cancer Clinical Trial using Questionnaire

M.D. Anderson Cancer Center - Recruiting N/A or older.
- A Pilot Study for Prospective Discovery of Possible Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations in Patients Undergoing Treatment for Locally Recurrent Rectal Adenocarcinoma.
Questionnaire

Rectal Cancer Clinical Trial

Stanford University - Recruiting 18 years or older.
- Perfusion CT as a Predictor of Treatment Response in Patients With Rectal Cancer.

Uterine Cervical Neoplasms, Endometrial Neoplasms, Anus Neoplasms Clinical Trial using Bone marrow sparing IMRT radiation therapy

University of Iowa - Recruiting 18 years or older.
- Improving Pelvic Cancer Patient Chemoradiotherapy Outcomes With FLT PET Imaging.
Bone marrow sparing IMRT radiation therapy

Rectal Cancer, or Rectum Clinical Trial using questionnaires; CSI-SH- Cancer Survivorship Intervention

Memorial Sloan-Kettering Cancer Center - Recruiting 21 years or older.
- The Sexual Health of Rectal Cancer Patients: A Pilot Study.
questionnaires; CSI-SH- Cancer Survivorship Intervention

Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of Clinical Trial using panitumumab; irinotecan hydrochloride; fluorouracil; leucovorin calcium

Ohio State University Comprehensive Cancer Center - Recruiting 18 years or older.
- A Phase II Study of Panitumumab in Combination With FOLFIRI After Progression on FOLFIRI Plus Bevacizumab in KRAS(Kirsten Rat Sarcoma) Wild-Type Metastatic Colorectal Cancer..
panitumumab; irinotecan hydrochloride; fluorouracil; leucovorin calcium

Patients Scheduled for Prostate Biopsy Because of Increased Serum Clinical Trial using urinary PCA3 test using Progensar PCA3 assay kit (Gen-Probe)

Hospices Civils de Lyon - Recruiting 18 Months or older.
- Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis.
urinary PCA3 test using Progensar PCA3 assay kit (Gen-Probe)

Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of Clinical Trial using Akt inhibitor MK2206; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 2 Study of MK-2206 in Previously Treated Metastatic Colorectal Cancer Patients Enriched for PTEN Loss and PIK3CA Mutation.
Akt inhibitor MK2206; laboratory biomarker analysis; pharmacological study

Mucinous Adenocarcinoma of the Rectum, Signet Ring Adenocarcinoma Clinical Trial using bevacizumab; oxaliplatin; leucovorin calcium; fluorouracil; laboratory biomarker analysis

USC/Norris Comprehensive Cancer Center - Recruiting 18 years or older.
- Phase II Trial Of Neoadjuvant Bevacizumab With Modified FOLFOX7 In Patients With Stage II And III Rectal Cancer.
bevacizumab; oxaliplatin; leucovorin calcium; fluorouracil; laboratory biomarker analysis

Medium and Lower Rectal Cancer Clinical Trial using Delayed coloanal anastomosis (ACAD); ACAI Group (coloanal anastomosis Immediate)

Institut Bergoni‚ - Recruiting 18 years to 75 years.
- Efficacy of Delayed Coloanal Anastomosis for Medium and Lower Rectum Cancer Treatment. Phase 2 Clinical Trial..
Delayed coloanal anastomosis (ACAD); ACAI Group (coloanal anastomosis Immediate)

Rectal Cancer, Gastric Cancer, Bone Marrow Toxicity, or Adverse E Clinical Trial using Bone Marrow-sparing Intensity-Modulated Radiotherapy

Chinese Academy of Medical Sciences - Recruiting 18 years to 75 years.
- Phase II Clinical Trial: The Effect of Bone Marrow-sparing Intensity-Modulated Radiotherapy (BMS-IMRT) on Reduction Acute Hematologic Toxicity in Gastric and Rectal Cancer Patients Treated With Concurrent Chemotherapy and IMRT.
Bone Marrow-sparing Intensity-Modulated Radiotherapy

Rectal Cancer Clinical Trial using loop ileostomi

Odense University Hospital - Recruiting 18 years or older.
- Early Closure of Temporary Loop Ileostomy After Rectal Resection for Cancer.
loop ileostomi

Colorectal Cancer Clinical Trial using capecitabine; 5-fluorouracil; Surgical Resection; Radiation therapy

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- A Biologic Study of Global Gene Expression, NF-Kappa B and p53 in Adenocarcinoma of the Rectum..
capecitabine; 5-fluorouracil; Surgical Resection; Radiation therapy

Cancer of the Rectum Clinical Trial using mFolfirinox; Radiotherapy 50Gy; Capecitabine; TME surgery; mFolfox6 or capecitabine

UNICANCER - Recruiting 18 years to 75 years.
- - Randomized Phase III Study Comparing Preoperative Chemoradiotherapy Alone Versus Neoadjuvant Chemotherapy With Folfirinox Regimen Followed by Preoperative Chemoradiotherapy for Patients With Resectable Locally Advanced Rectal Cancer.
mFolfirinox; Radiotherapy 50Gy; Capecitabine; TME surgery; mFolfox6 or capecitabine

Rectal Cancer, Colon Cancer, Metastasis, or Adenocarcinoma Clinical Trial using Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Abramson Cancer Center of the University of Pennsylvania - Recruiting 18 years or older.
- A Phase I/II Pharmacodynamic Study of Hydroxychloroquine in Combination With FOLFOX Plus Bevacizumab to Inhibit Autophagy in Colorectal Cancer.
Hydroxychloroquine; Oxaliplatin; Leucovorin; 5-fluorouracil; Bevacizumab

Rectal Cancer, or Colon Cancer Clinical Trial using polyethylene glycol; No Preparation

PVS Memorial Hospital - Recruiting 25 years to 75 years.
- A Randomised Controlled Trial On Mechanical Bowel Preparation Versus No Mechanical Bowel Preparation In Elective Laparoscopic Surgery For Left Sided Colonic Tumours.
polyethylene glycol; No Preparation

Rectal Neoplasm Clinical Trial using Hand-sewn coloanal anastomosis; Two staged Turnbull-Cutait procedure; Ultralow anterior rectal resection with total mesorectal excision

Hospital Universitari de Bellvitge - Recruiting 18 years to 74 years.
- Prospective Multicenter Randomized Controlled Trial Comparing Postoperative Complications and Quality of Life in Low Rectal Cancer Surgery Between Coloanal Anastomosis and Lateral Ileostomy Versus Two-Stage Turnbull-Cutait Coloanal Anastomosis.
Hand-sewn coloanal anastomosis; Two staged Turnbull-Cutait procedure; Ultralow anterior rectal resection with total mesorectal excision

Rectal Cancer Clinical Trial using radiation therapy; capecitabine (625mg/m2,bid,d1-5 qw)and oxaliplatin (85mg/m2 d1 qw)

Fudan University - Recruiting 18 years to 75 years.
- Detection and Enumeration of Circulating Tumor Cells in Rectal Cancer.
radiation therapy; capecitabine (625mg/m2,bid,d1-5 qw)and oxaliplatin (85mg/m2 d1 qw)

Rectal Cancer Clinical Trial using XELAC RT; XELOX RT

Catholic University of the Sacred Heart - Recruiting 18 years or older.
- INTEnsification Radiotherapy With Accelerated Fractionation or ChemoTherapy And Local Excision After 3D External Radio-chemotherapy.
XELAC RT; XELOX RT

Rectal Cancer, or Liver Metastases Clinical Trial using Capecitabine, Oxaliplatin; Radiotherapy

Asan Medical Center - Recruiting 20 years to 75 years.
- Randomized Phase II Trial of Preoperative Chemoradiation With or Without Induction Chemotherapy In Patients With Locally Advanced Or Borderlinely Resectable Rectal Cancer With Resectable Synchronous Liver Metastases.
Capecitabine, Oxaliplatin; Radiotherapy

Low Anterior Resection Syndrome, or Rectal Cancer Clinical Trial using intra-rectal Botulinum toxin A injection

Centre hospitalier de l'Universit‚ de Montr‚al (CHUM) - Recruiting 18 years to 80 years.
- The Value of Botox-A Administered as a Single Intra-rectal Injection for the Management of Low Anterior Resection Syndrome: A Phase II Study.
intra-rectal Botulinum toxin A injection

Rectal Cancer Clinical Trial using VSL#3; Placebo

Catholic University of the Sacred Heart - Recruiting 18 years or older.
- A Phase III, Randomized, Double-Blind Placebo Controlled Study of the Probiotic Preparation VSL#3r Versus Placebo in Increasing the Pathological Major Response Rate in Patients Receiving Concurrent Chemotherapy and Pelvic Radiation Therapy.
VSL#3; Placebo

Rectal Tumour Clinical Trial using Capecitabine; radiotherapy; TME resection; TEM surgery

Radboud University - Recruiting 18 years or older.
- CHEMORADIOTHERAPY FOR RECTAL CANCER IN THE DISTAL RECTUM FOLLOWED BY ORGANSPARING TRANSANAL ENDOSCOPIC MICROSURGERY: CARTS Study CApecitabine, Radiotherapy and Tem Surgery. A PHASE II, FEASIBILITY TRIAL.
Capecitabine; radiotherapy; TME resection; TEM surgery

Colorectal Cancer Clinical Trial using cetuximab; irinotecan hydrochloride; conventional surgery; neoadjuvant therapy; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years to 74 years.
- Neoadjuvant Conformal Radiotherapy and Concomitant CPT-11 and EGFR Inhibition With Cetuximab in Patients With Rectal Cancer Phase I Study.
cetuximab; irinotecan hydrochloride; conventional surgery; neoadjuvant therapy; 3-dimensional conformal radiation therapy; intensity-modulated radiation therapy

Rectal Neoplasms Clinical Trial using Mesorectal excision with lateral lymph node dissection; Mesorectal excision without lateral lymph node excision

Japan Clinical Oncology Group - Recruiting 21 years to 74 years.
- Mesorectal Excision With Lateral Lymph Node Dissection Versus Without Lateral Lymph Node Dissection for Clinical Stage II, III Lower Rectal Cancer (JCOG0212).
Mesorectal excision with lateral lymph node dissection; Mesorectal excision without lateral lymph node excision

Rectal Cancer Clinical Trial using Short course of radiotherapy; Radiochemotherapy

Polish Colorectal Cancer Study Group - Recruiting 18 years or older.
- The Randomised Study of Preoperative Radiotherapy and Local Excision for Radiosensitive Rectal Cancer.
Short course of radiotherapy; Radiochemotherapy

Rectal Cancer Clinical Trial using Short course of radiotherapy; Radiochemotherapy

Polish Colorectal Cancer Study Group - Recruiting 18 years to 75 years.
- Short-course Preoperative Radiotherapy With Consolidating Chemotherapy vs. Preoperative Chemoradiation in Patients With Unresectable Rectal Cancer: Phase III Study.
Short course of radiotherapy; Radiochemotherapy

Rectal Cancer Clinical Trial

St. Claraspital AG - Recruiting N/A or older.
- .

Colorectal Cancer Clinical Trial using FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase II Open- Labeled, Prospective Study to Determine the Efficacy of Pre- Operative Chemotherapy With Six Cycles of Modified FOLFOX 6 Followed by Total Mesorectal Excision (TME) Followed by an Additional Six Cycles of FOLFOX 6.
FOLFOX regimen; fluorouracil; leucovorin calcium; oxaliplatin; adjuvant therapy; neoadjuvant therapy; quality-of-life assessment; therapeutic surgical procedure

Colorectal Surgery Clinical Trial using Transrectal vacuum assisted drainage

Hvidovre University Hospital - Recruiting 18 years or older.
- Transrectal Vacuum Assisted Drainage: A NEW METHOD OF TREATING ANASTOMOTIC LEAKAGE AFTER RECTAL RESECTION. A Prospective Randomized Multicenter Study in Cooperation With 'The Danish Colorectal Cancer Group'.
Transrectal vacuum assisted drainage

Primary Rectal Cancer Clinical Trial using radiotherapy

Kaunas University of Medicine - Recruiting 18 years to 80 years.
- Preoperative Chemoradiation Versus Short Term Radiation Alone With Delayed Surgery for Stage II and III Resectable Rectal Cancer.
radiotherapy

Colonic Neoplasms Clinical Trial using Indium labeled IMP-205xm734

Radboud University - Recruiting 18 years or older.
- Radioimmunodetection of CEA-Producing Tumors Using a Bispecific Antibody Pre-Targeting Method and an In-Labeled Peptide.
Indium labeled IMP-205xm734