24 results found.

Recurrent Non-small Cell Lung Cancer, or Stage IV Non-small Cell Clinical Trial using cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Trial of XL184 (Cabozantinib) Plus Erlotinib in Patients With Advanced EGFR-Mutant Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Therapy.
cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

Recurrent Small Cell Lung Cancer Clinical Trial using veliparib; temozolomide; placebo; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Multi-center, Randomized, Double-Blind Phase II Study Comparing ABT-888, a PARP Inhibitor, Versus Placebo With Temozolomide in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer.
veliparib; temozolomide; placebo; laboratory biomarker analysis

Non-Small Cell Lung Cancer Clinical Trial using GDC-0941; carboplatin; paclitaxel; bevacizumab; Placebo

Genentech - Recruiting 18 years or older.
- A Phase II, Double-Blind, Placebo-Controlled, Randomized Study Evaluating the Safety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without GDC-0941 in Patients With Previously Untreated Advanced or Recurrent Non-small Cell Lung Cancer.
GDC-0941; carboplatin; paclitaxel; bevacizumab; Placebo

Non-small Cell Lung Cancer, Progression of Non-small Cell Lung Ca Clinical Trial using Docetaxel; HyperAcuter-Lung Immunotherapy; Gemcitabine; Pemetrexed

NewLink Genetics Corporation - Recruiting 18 years or older.
- An Open-label, Randomized Phase IIB/III Active Control Study of Second-line Hyper-Acute(R)-Lung (Tergenpumatucel-L) Immunotherapy Versus Docetaxel in Progressive or Relapsed Non-Small Cell Lung Cancer.
Docetaxel; HyperAcuter-Lung Immunotherapy; Gemcitabine; Pemetrexed

Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lu Clinical Trial using positron emission tomography; computed tomography; intensity-modulated radiation therapy; carboplatin; paclitaxel

Albert Einstein College of Medicine of Yeshiva University - Recruiting 18 years or older.
- PET-Adjusted IMRT for NSCLC Trial (PAINT).
positron emission tomography; computed tomography; intensity-modulated radiation therapy; carboplatin; paclitaxel

Anxiety Disorder, Recurrent Non-small Cell Lung Cancer, or Stage Clinical Trial using counseling intervention; questionnaire administration; quality-of-life assessment

Stanford University - Recruiting N/A or older.
- Intervention Development for Anxiety in Metastatic NSCLC Patients and Their Caregivers.
counseling intervention; questionnaire administration; quality-of-life assessment

Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lu Clinical Trial using HPPH; therapeutic conventional surgery; photodynamic therapy

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Phase I Study of Surgery Plus Intraoperative Photodynamic Therapy (PDT) With Temoporfin in Patients With Resectable Primary Non-Small Cell Lung Cancer (NSCLC) With Ipsilateral Thoracic Nodal (N1 or N2) or T3/T4 Disease.
HPPH; therapeutic conventional surgery; photodynamic therapy

Adenocarcinoma of the Lung, Bronchoalveolar Cell Lung Cancer, Lar Clinical Trial using PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

City of Hope Medical Center - Recruiting 18 years or older.
- Phase I Trial of BKM120 in Combination With Carboplatin and Pemetrexed in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC).
PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

Recurrent Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lu Clinical Trial using trametinib; carboplatin; paclitaxel; intensity-modulated radiation therapy; 3-dimensional conformal radiation therapy; image-guided radiation therapy; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Trametinib in Combination With Chemoradiation for KRAS Mutant Non-Small Cell Lung Cancer.
trametinib; carboplatin; paclitaxel; intensity-modulated radiation therapy; 3-dimensional conformal radiation therapy; image-guided radiation therapy; pharmacological study; laboratory biomarker analysis

Recurrent Small Cell Lung Cancer Clinical Trial using etirinotecan pegol (NKTR 102); pharmacogenomic studies; laboratory biomarker analysis

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Phase II Study of Single Agent Topoisomerase-I Inhibitor Polymer Conjugate, Etirinotecan Pegol (NKTR-102), in Patients With Relapsed Small Cell Lung Cancer.
etirinotecan pegol (NKTR 102); pharmacogenomic studies; laboratory biomarker analysis

Non-small Cell Lung Cancer Metastatic, or Non-small Cell Lung Can Clinical Trial using MLN8237 and Erlotinib

Fox Chase Cancer Center - Recruiting 18 years or older.
- A Phase I/II Trial to Assess Safety and Tolerability of an Oral Aurora Kinase A Inhibitor, MLN8237, In Combination With Erlotinib In Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer.
MLN8237 and Erlotinib

Lung Cancer - Non Small Cell Clinical Trial using Ipilimumab; Placebo; Paclitaxel; Carboplatin

Bristol-Myers Squibb - Recruiting 18 years or older.
- Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin Versus Placebo in Addition to Paclitaxel and Carboplatin in Subjects With Stage IV/Recurrent Non Small Cell Lung Cancer (NSCLC).
Ipilimumab; Placebo; Paclitaxel; Carboplatin

Extensive Stage Small Cell Lung Cancer, Limited Stage Small Cell Clinical Trial using technetium Tc 99m-labeled macroaggregated albumin; 99mTc-DTPA; single photon emission computed tomography; computed tomography

University of Washington - Recruiting 19 years or older.
- Pulmonary Functional Imaging for Radiation Treatment Planning for Lung Cancer.
technetium Tc 99m-labeled macroaggregated albumin; 99mTc-DTPA; single photon emission computed tomography; computed tomography

Recurrent Small Cell Lung Cancer Clinical Trial using SC16LD6.5

Stem CentRx, Inc. - Recruiting 18 years or older.
- Phase I/II Open Label Dose Escalation Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of SC16LD6.5 as a Single Agent in Patients With Recurrent Small Cell Lung Cancer.
SC16LD6.5

Recurrent Small Cell Lung Cancer Clinical Trial using linsitinib; topotecan hydrochloride; laboratory biomarker analysis; pharmacological study

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Randomized Phase II Study of Single Agent OSI-906, an Oral, Small Molecule, Tyrosine Kinase Inhibitor (TKI) of the Insulin Growth Factor-1 Receptor (IGF-1R) Versus Topotecan for the Treatment of Patients With Relapsed Small Cell Lung Cancer (SCLC).
linsitinib; topotecan hydrochloride; laboratory biomarker analysis; pharmacological study

Non-small Cell Lung Cancer Metastatic, or Non-small Cell Lung Can Clinical Trial using Gemcitabine; Pemetrexed; Cisplatin

National Cancer Institute, Naples - Recruiting 70 years or older.
- A Factorial Study Comparing Pemetrexed With Gemcitabine and Testing the Efficacy of the Addition of Cisplatin in Elderly Patients With Non Squamous Advanced, Metastatic or Recurrent NSCLC..
Gemcitabine; Pemetrexed; Cisplatin

Recurrent Non-small Cell Lung Cancer, Stage IIIA Non-small Cell L Clinical Trial using therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Pilot Study of Stereotactic Body Radiation Therapy (SBRT) After TEMLA for Stage III and IV (Oligometastatic) Non-Small Cell Lung Cancer.
therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Non-small Cell Lung Cancer, or Unresectable Clinical Trial

University of Athens - Recruiting 18 years or older.
- Open-label Study of Bevacizumab (AVASTINr) in Combination With Platinum-containing Chemotherapy as First-line Treatment of Patients With Advanced or Recurrent Non-squamous Non-small Cell Lung Cancer.

Patients Must Have Histologically or Cytologically Confirmed Non- Clinical Trial using Paclitaxel, Carboplatin, Bevacizumab, and Metformin; Paclictaxl, Carboplatin, and Bevcizumab.

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Randomized Phase II Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Previously Untreated Advanced/Metastatic Pulmonary Adenocarcinoma.
Paclitaxel, Carboplatin, Bevacizumab, and Metformin; Paclictaxl, Carboplatin, and Bevcizumab.

Recurrent Non-small Cell Lung Cancer, Stage IIIA Non-small Cell L Clinical Trial using entinostat; azacitidine; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I/II Study of Entinostat in Combination With 5-Azacytidine in Patients With Recurrent Advanced Non-Small Cell Lung Cancer.
entinostat; azacitidine; pharmacological study; laboratory biomarker analysis

Recurrent Non-small Cell Lung Cancer, or Stage IV Non-small Cell Clinical Trial using paclitaxel albumin-stabilized nanoparticle formulation; laboratory biomarker analysis

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- A Phase II Study of Weekly ABRAXANEr (Nab-paclitaxel) for Patients With Advanced NSCLC With EGFR Mutations Following Front-line Therapy With EGFR Tyrosine Kinase Inhibitors.
paclitaxel albumin-stabilized nanoparticle formulation; laboratory biomarker analysis

Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer, Large Clinical Trial using hypofractionated radiation therapy; laboratory biomarker analysis; image-guided radiation therapy; carboplatin; paclitaxel; stereotactic body radiation therapy

Jonsson Comprehensive Cancer Center - Recruiting 18 years or older.
- Image-Guided Hypofractionated Radiotherapy With Stereotactic Boost and Chemotherapy for Inoperable Stage II-III Non-Small Cell Lung Cancer.
hypofractionated radiation therapy; laboratory biomarker analysis; image-guided radiation therapy; carboplatin; paclitaxel; stereotactic body radiation therapy

Non-small Cell Lung Cancer Metastatic, or Non-small Cell Lung Can Clinical Trial

Chonnam National University Hospital - Recruiting 19 years to 80 years.
- Phase 4 Study of Response to EGFR-TKI and Correlation With C-met Expression and EGFR Gene Mutation in NSCLC Patients Treated With Erlotinib.

Non-small Cell Lung Cancer Clinical Trial using Pemetrexed; pemetrexed and erlotinib

Montefiore Medical Center - Recruiting 18 years or older.
- A Randomized Phase II Study of Schedule-Modulated Concomitant Pemetrexed and Erlotinib Versus Single Agent Pemetrexed in Patients With Progressive or Recurrent Non-Small Cell Lung Cancer (NSCLC).
Pemetrexed; pemetrexed and erlotinib