14 results found.

Arthroplasty, Replacement, or Thromboembolism Clinical Trial

Boehringer Ingelheim - Recruiting 18 years or older.
- Observational Cohort Study to Evaluate Safety and Efficacy of Pradaxa (Dabigatran Etexilate) in Patients With Moderate Renal Impairment (Creatinine Clearance 30-50 ml/Min) Undergoing Elective Total Hip Replacement Surgery or Total Knee Replacement Surgery.

Renal Insufficiency, or Renal Impairment Clinical Trial using sugammadex

Merck Sharp & Dohme Corp. - Recruiting 18 years or older.
- An Open-Label, Single-Dose Study to Investigate the Pharmacokinetics of MK-8616 in Subjects With Moderate and Severe Renal Insufficiency.

Neoplasms Clinical Trial using Regorafenib (Stivarga, BAY73-4506)

Bayer - Recruiting 18 years or older.
- A Phase I, Multi-center, Non-randomized, Open Label, Parallel-group Study Evaluating the Pharmacokinetics and Safety of Regorafenib (BAY 73-4506) in Cancer Subjects With Severe Renal Impairment Compared to a Control Group.
Regorafenib (Stivarga, BAY73-4506)

Solid Tumours Clinical Trial using Olaparib tablet dosing

AstraZeneca - Recruiting 18 years to 75 years.
- An Open-label, Non-randomised, Multicentre, Comparative, Phase I Study of the Pharmacokinetics, Safety and Tolerability of Olaparib Following a Single Oral 300 mg Dose to Patients With Advanced Solid Tumours and Normal Renal Function or Renal Impairment.
Olaparib tablet dosing

Renal Impairment, Renal Insufficiency, Kidney Disease, or Kidney Clinical Trial using IDN-6556

Conatus Pharmaceuticals Inc. - Recruiting 18 years to 75 years.
- An Open-Label Pharmacokinetic and Pharmacodynamic Study of a Single Dose of IDN-6556 in Subjects With Severe Renal Impairment and in Matched Healthy Volunteers.

Renal Impairment, Kidney Diseases, Urologic Diseases, Cancer, Hyp Clinical Trial using Renal hypothermia

Ottawa Hospital Research Institute - Recruiting 18 years or older.
- A Randomized Controlled Trial of Renal Hypothermia During Partial Nephrectomy.
Renal hypothermia

Renal Impairment Clinical Trial using Nalmefene 18 mg

H. Lundbeck A/S - Recruiting 18 years to 70 years.
- An Interventional, Single-site, Open-label, Four-group, Single-dose Study Investigating the Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment (Mild, Moderate, or Severe) and in Healthy Subjects.
Nalmefene 18 mg

Cardiomyopathy, or Renal Impairment Clinical Trial using Tadalafil; Placebo

Mayo Clinic - Recruiting 21 years to 90 years.
- Define in Preclinical Systolic Dysfunction (PSD) With Renal Dysfunction, the Cardiorenal and Humoral Actions of Chronic Type V Phosphodiesterase (PDEV) Inhibition.
Tadalafil; Placebo

Hepatitis C Virus Clinical Trial using GS-5816

Gilead Sciences - Recruiting 18 years to 79 years.
- A Phase 1, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Renal Function and Severe Renal Impairment.

End Stage Renal Disease Clinical Trial using Kidney Transplant

University of Kansas - Recruiting 30 years to 70 years.
- Cognitive Impairment and Imaging Correlates in End Stage Renal Disease.
Kidney Transplant

Advanced Solid Tumors, Kidney Disease, or Renal Impairment Clinical Trial using AMG 386 + Paclitaxel; AMG 386

Amgen - Recruiting 18 years or older.
- An Open-label Pharmacokinetic Study of AMG 386 in Advanced Cancer Subjects With Normal and Impaired Renal Function.
AMG 386 + Paclitaxel; AMG 386

Diabetes Mellitus Clinical Trial using Linagliptin

Profil Institut fr Stoffwechselforschung GmbH - Recruiting 18 years to 70 years.

Disseminated Intravascular Coagulation Clinical Trial using ART-123

Asahi Kasei Pharma Corporation - Recruiting 20 years or older.
- A Post-Marketing Clinical Pharmacokinetics Study of ART-123 in DIC Subjects With Renal Impairment.

Systemic Inflammatory Response Syndrome, Oliguria, or Renal Impai Clinical Trial using Sodium bicarbonate; Sodium chloride

Austin Health - Recruiting 18 years or older.
- A Randomized Double-blind Controlled Pilot Feasibility and Safety Trial of NGAL-directed Sodium Bicarbonate to Protect Renal Function in Patients With the Systemic Inflammatory Response Syndrome, Oliguria and Elevated Lipocalin Levels.
Sodium bicarbonate; Sodium chloride