30 results found.

Epilepsy, or Partial-onset Seizures Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 16 years to 70 years.
- A Multi-center, Open-label, Uncontrolled, Long-term, Extension Study to Evaluate the Safety and Efficacy of Lacosamide as Adjunctive Therapy in Japanese and Chinese Adults With Partial-onset Seizures With or Without Secondary Generalization.
Lacosamide

Epilepsy, or Partial Seizures Clinical Trial using Levetiracetam; Carbamazepine

UCB, Inc. - Recruiting 16 years or older.
- An Open-label, Randomized, Parallel-group, Active-controlled Study Comparing the Efficacy and Safety of Levetiracetam to Carbamazepine Used as Monotherapy in Subjects Newly or Recently Diagnosed as Epilepsy and Partial-onset Seizures.
Levetiracetam; Carbamazepine

Epilepsy Clinical Trial using Lacosamide; Placebo

UCB, Inc. - Recruiting 4 years to 17 years.
- A Multicenter, Double Blind, Randomized, Placebo Controlled, Parallel Group Study to Investigate the Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects With Epilepsy ò4 Years to <17 Years of Age With Partial Onset Seizures.
Lacosamide; Placebo

Epilepsy Clinical Trial using Levetiracetam; Topiramate

UCB, Inc. - Recruiting 16 years to 80 years.
- A Randomized, Open-label, Parallel Group, Multi-center, Comparative, Phase IV Trial of Levetiracetam (LEV) Versus Topiramate (TPM) as Adjunctive Therapy to Evaluate Efficacy and Safety in Adult Subjects With Refractory Partial Onset Seizures.
Levetiracetam; Topiramate

Epilepsy Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 1 Month to 18 years.
- A MULTI-CENTER, OPEN-LABEL, EXPLORATORY STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF LACOSAMIDE AS ADJUNCTIVE THERAPY IN SUBJECTS ò1 MONTH TO <18 YEARS WITH EPILEPSY SYNDROMES ASSOCIATED WITH GENERALIZED SEIZURES..
Lacosamide

Epilepsies, Partial Clinical Trial using Lyrica (pregabalin); placebo

Pfizer - Recruiting 18 years to 65 years.
- Prospective Randomized 12-Week Controlled Study Of Visual Field Change In Subjects With Partial Seizures Receiving Pregabalin Or Placebo.
Lyrica (pregabalin); placebo

Generalized Tonic Clonic Seizures Clinical Trial using Pregabalin Dose Level 1; Pregabalin Dose Level 2; Placebo

Pfizer - Recruiting 5 years to 65 years.
- A Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center Trial of Pregabalin As Adjunctive Therapy in Pediatric and Adult Subjects With Primary Generalized Tonic Clonic Seizures - Protocol A0081105.
Pregabalin Dose Level 1; Pregabalin Dose Level 2; Placebo

Epilepsy, Partial Seizures Clinical Trial using Pregabalin add-on therapy

Pfizer - Recruiting 4 years to 16 years.
- A Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study of the Efficacy and Safety of Pregabalin As Adjunctive Therapy in Children 4 -16 Years of Age With Partial Onset Seizures.
Pregabalin add-on therapy

Epilepsy, Partial Seizures Clinical Trial using Pregabalin

Pfizer - Recruiting 1 Month to 65 years.
- A 12-Month Open-Label Study To Evaluate The Safety And Tolerability Of Pregabalin As Adjunctive Therapy In Children 1 Month To 16 Years Of Age With Partial Onset Seizures And Child And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures.
Pregabalin

Epilepsy, or Monotherapy Clinical Trial using Lacosamide; Carbamazepine-Controlled Release

UCB, Inc. - Recruiting 16 years or older.
- A Multicenter, Double-blind, Double-dummy, Randomized, Positive- Controlled Study Comparing the Efficacy and Safety of Lacosamide (200 to 600 mg/Day) to Controlled Release Carbamazepine (400 to 1200 mg/Day), Used as Monotherapy in Subjects (ò 16 Years) Newly or Recently Diagnosed With Epilepsy and Experiencing Partial-onset or Generalized Tonic-clonic Seizures..
Lacosamide; Carbamazepine-Controlled Release

Epilepsy, or Monotherapy Clinical Trial using Lacosamide; Carbamazepine-Controlled Release (CBZ-CR)

UCB, Inc. - Recruiting N/A or older.
- A Multicenter, Double-blind, Double-dummy, Follow up Study Evaluating the Long-term Safety of Lacosamide in Comparison With Controlled-release Carbamazepine Used as Monotherapy in Subjects With Partial-onset or Generalized Tonic-clonic Seizures ò16 Years of Age Coming From the SP0993 Study..
Lacosamide; Carbamazepine-Controlled Release (CBZ-CR)

Metabolic Disease, or Seizures Clinical Trial using SGS-742; Placebo

National Institutes of Health Clinical Center (CC) - Recruiting 8 years or older.
- Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency.
SGS-742; Placebo

Seizures, Epilepsy, Partial Epilepsy, or Depression Clinical Trial using Buspirone

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 65 years.
- A Phase Two Clinical Trial of Buspirone Therapy in Localization-Related Epilepsy.
Buspirone

Psycogenic Movement Disorders, or Non-Epileptic Seizures Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 90 years.
- Neurobiological Studies of Psychogenic Movement Disorders and Non-Epileptic Seizures.

Epilepsy Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 60 years.
- Imaging Serotoninergic Neurotransmission in Epilepsy.

Partial-onset Seizures Clinical Trial using E2007; Placebo

Eisai Inc. - Recruiting 12 years or older.
- A Double-blind, Placebo-controlled, Parallel-group Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset Seizures.
E2007; Placebo

Autistic Disorder, Seizures, or Irritability Clinical Trial using N-Acetyl Cysteine (NAC)

Nationwide Children's Hospital - Recruiting 6 years to 21 years.
- Pilot Study of N-acetyl Cysteine for Refractory Generalized Epilepsy in Children With Autism.
N-Acetyl Cysteine (NAC)

Drug Resistant Partial Onset Seizure Clinical Trial using ganaxolone; Placebo

Marinus Pharmaceuticals - Recruiting 18 years or older.
- A Multicenter, Double Blind, Randomized, Placebo-Controlled Trial to Determine the Efficacy and Safety of Ganaxolone as Adjunctive Therapy for Adults With Drug-Resistant Partial-Onset Seizures Followed by Long-term Open-Label Treatment.
ganaxolone; Placebo

Seizures, or Epilepsy Clinical Trial using Patient Education

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Increasing Self-Efficacy and Outcome Expectations For Exercise in Adults With Epilepsy: An Educational Motivation Intervention - E-MOVE.
Patient Education

Partial Epilepsy Clinical Trial using YKP3089; Placebo

SK Life Science - Recruiting 18 years to 70 years.
- A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Response Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures, With Optional Open-Label Extension.
YKP3089; Placebo

Tuberous Sclerosis Complex-associated Refractory Seizures Clinical Trial using RAD001; Placebo

Novartis - Recruiting 1 year to 65 years.
- A Three-arm, Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Two Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) Who Have Refractory Partial-onset Seizures.
RAD001; Placebo

Metastatic Castration- Resistant Prostate Cancer (mCRCP) Clinical Trial using Enzalutamide

Astellas Pharma Inc - Recruiting N/A or older.
- A Multicenter, Single-Arm, Open-Label, Post-Marketing Safety Study to Evaluate the Risk of Seizure Among Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated With Enzalutamide Who Are at Potential Increased Risk of Seizure.
Enzalutamide

Epilepsy Clinical Trial using Night Watch Seizure Detection Device and Warning System

Brain Sentinel - Recruiting 2 years or older.
- A Pivotal, Phase III Trial of Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients.
Night Watch Seizure Detection Device and Warning System

Epilepsy Clinical Trial using Lacosamide

UCB, Inc. - Recruiting 1 Month to 17 years.
- A Multicenter, Open-Label Study To Investigate The Safety, Tolerability, And Pharmacokinetics Of Lacosamide (LCM) Oral Solution (Syrup) As Adjunctive Therapy In Children With Partial-Onset Seizures.
Lacosamide

Intracranial Aneurysms, or Seizures Clinical Trial using Levetiracetam

Indiana University - Recruiting N/A or older.
- Seizure Prophylaxis in Aneurysm Repair.
Levetiracetam

Seizures Clinical Trial using Bumetanide; Normal Saline

Soul, Janet , M.D. - Recruiting N/A or older.
- Pilot Study of Bumetanide for Newborn Seizures: A Phase I Study of Pharmacokinetics and Safety of Bumetanide for Neonatal Seizures.
Bumetanide; Normal Saline

Partial Onset Seizures Clinical Trial using Eslicarbazepine Acetate tablets

Eisai Inc. - Recruiting 18 years or older.
- An Open-label, Multi-centre, Multi-national Post-marketing Non-interventional Prospective Study Evaluating Retention Rate, Seizure Control and Tolerability of Eslicarbazepine Acetate (ESL) as Adjunctive Treatment to One Baseline Antiepileptic Drug in Adult Patients With Partial-Onset Seizures With or Without Secondary Generalisation.
Eslicarbazepine Acetate tablets

Epilepsy, or Seizures Clinical Trial

Capital District Health Authority, Canada - Recruiting 17 years or older.
- Neuroimaging Predictors of Treatment Failure in Adult New-onset Epilepsy.

Complex Partial Seizures Clinical Trial using vigabatrin

University of Pennsylvania - Recruiting 18 years or older.
- Sabril for Treatment of Adult Refractory Partial Seizures Symptomatic of Tuberous Sclerosis: An Open Label, Phase IV Prospective Safety and Tolerability Study.
vigabatrin

Epilepsy, Seizures, Cognition Disorders, or Neuronal Migration Di Clinical Trial

Harvard University Faculty of Medicine - Recruiting N/A or older.
- Human Epilepsy Genetics--Neuronal Migration Disorders Study.