79 results found.

Non-Small Cell Lung Cancer, Anemia, Cancer, or Lung Cancer Clinical Trial using darbepoetin alfa 500 mcg Q3W; placebo

Amgen - Recruiting 18 years or older.
- A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long-term Safety and Efficacy of Darbepoetin Alfa Administered at 500 µg Once-Every-3-Weeks in Anemic Subjects With Advanced Stage Non-small Cell Lung Cancer Receiving Multi-cycle Chemotherapy.
darbepoetin alfa 500 mcg Q3W; placebo

Recurrent Non-small Cell Lung Cancer, or Stage IV Non-small Cell Clinical Trial using cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Trial of XL184 (Cabozantinib) Plus Erlotinib in Patients With Advanced EGFR-Mutant Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Therapy.
cabozantinib-s-malate; erlotinib hydrochloride; laboratory biomarker analysis

Stage III Non-small Cell Lung Cancer Clinical Trial using 1 MRI scan

UMC Utrecht - Recruiting 18 years or older.
- MRI for Radiotherapy Treatment Planning of Stage III NSCLC: an MRI Optimization Study in Healthy Volunteers and Patients.
1 MRI scan

Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lu Clinical Trial using positron emission tomography; computed tomography; intensity-modulated radiation therapy; carboplatin; paclitaxel

Albert Einstein College of Medicine of Yeshiva University - Recruiting 18 years or older.
- PET-Adjusted IMRT for NSCLC Trial (PAINT).
positron emission tomography; computed tomography; intensity-modulated radiation therapy; carboplatin; paclitaxel

Non-Small-Cell Lung Cancer Stage IIIB, Non-Small-Cell Lung Cancer Clinical Trial using bavituximab; Docetaxel; Placebo (for bavituximab)

Peregrine Pharmaceuticals - Recruiting 18 years or older.
- SUNRISE: A Phase III, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial of Bavituximab Plus Docetaxel Versus Docetaxel Alone as Second-Line Therapy in Patients With Stage IIIb/IV Non-Squamous Non Small-Cell Lung Cancer.
bavituximab; Docetaxel; Placebo (for bavituximab)

Non-small Cell Lung Cancer Clinical Trial using Nivolumab; Gemcitabine; Cisplatin; Pemetrexed; Paclitaxel; Carboplatin; Bevacizumab; Erlotinib; Ipilimumab

Bristol-Myers Squibb - Recruiting 18 years or older.
- A Multi-arm Phase I Safety Study of Nivolumab in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC).
Nivolumab; Gemcitabine; Cisplatin; Pemetrexed; Paclitaxel; Carboplatin; Bevacizumab; Erlotinib; Ipilimumab

Non-Small Cell Lung Cancer Clinical Trial using erlotinib; placebo; onartuzumab

Hoffmann-La Roche - Recruiting 18 years or older.
- A RANDOMIZED, PHASE III, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF ONARTUZUMAB IN COMBINATION WITH ERLOTINIB AS FIRST-LINE TREATMENT FOR PATIENTS WITH MET-POSITIVE UNRESECTABLE STAGE IIIB OR IV NON-SMALL CELL LUNG CANCER (NSCLC) CARRYING AN ACTIVATING EGFR MUTATION.
erlotinib; placebo; onartuzumab

Non Small Cell Lung Cancer Clinical Trial using DCE-MRI scan; Stereotactic Body Radiation Therapy; 4D-CT scan

Dana-Farber Cancer Institute - Recruiting 18 years or older.
- Feasibility Study of the Utility of Pulmonary Dynamic Contrast Enhanced MRI for Assessment of Tumor Response and Lung Injury and for Treatment Planning for Stereotactic Body Radiation Therapy for Early Stage Non-Small Cell Lung Cancer.
DCE-MRI scan; Stereotactic Body Radiation Therapy; 4D-CT scan

Lung Cancer Clinical Trial using panitumumab; carboplatin; paclitaxel

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Randomized Phase II Study of Pre-operative Chemoradiotherapy +/- Panitumumab (IND #110152) Followed by Consolidation Chemotherapy +/- Cetuximab in Potentially Operable Locally Advanced (Stage IIIA, N2+) Non-Small Cell Lung Cancer (Cetuximab Closed as of 05/14/10).
panitumumab; carboplatin; paclitaxel

Non-small Cell Lung Cancer Metastatic Clinical Trial using Ramucirumab; Placebo; Docetaxel

Eli Lilly and Company - Recruiting 20 years or older.
- A Randomized, Double-Blind, Phase 2 Study of Docetaxel and Ramucirumab Versus Docetaxel and Placebo in the Treatment of Stage IV Non-Small Cell Lung Cancer Following Disease Progression After One Prior Platinum-Based Therapy.
Ramucirumab; Placebo; Docetaxel

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage I Clinical Trial using Selumetinib; Docetaxel; Placebo; Pegylated G-CSF

AstraZeneca - Recruiting 18 years or older.
- A Phase III, Double-Blind, Randomised, Placebo-Controlled Study to Assess the Efficacy and Safety of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Combination With Docetaxel, in Patients Receiving Second Line Treatment for KRAS Mutation-Positive Locally Advanced or Metastatic Non Small Cell Lung Cancer (Stage IIIB - IV) (SELECT 1).
Selumetinib; Docetaxel; Placebo; Pegylated G-CSF

Neoplasms,, Metastatic Cancer,, Non-Small Cell Lung Cancer, or Ad Clinical Trial using AZD6244; Docetaxel

AstraZeneca - Recruiting 20 years or older.
- A Phase I, Open-Label Study to Investigate the Safety and Tolerability of AZD6244 (Selumetinib) When Given as a Monotherapy in Japanese Patients With Advanced Solid Malignancies, and When Given in Combination With Docetaxel as 2nd Line Therapy in Japanese Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (Stage IIIB-IV).
AZD6244; Docetaxel

Anxiety Disorder, Recurrent Non-small Cell Lung Cancer, or Stage Clinical Trial using counseling intervention; questionnaire administration; quality-of-life assessment

Stanford University - Recruiting N/A or older.
- Intervention Development for Anxiety in Metastatic NSCLC Patients and Their Caregivers.
counseling intervention; questionnaire administration; quality-of-life assessment

Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lu Clinical Trial using HPPH; therapeutic conventional surgery; photodynamic therapy

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Phase I Study of Surgery Plus Intraoperative Photodynamic Therapy (PDT) With Temoporfin in Patients With Resectable Primary Non-Small Cell Lung Cancer (NSCLC) With Ipsilateral Thoracic Nodal (N1 or N2) or T3/T4 Disease.
HPPH; therapeutic conventional surgery; photodynamic therapy

Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lu Clinical Trial using photon beam radiation therapy; proton beam radiation therapy; paclitaxel; carboplatin; etoposide; cisplatin; quality-of-life assessment; questionnaire administration

Radiation Therapy Oncology Group - Recruiting 18 years or older.
- Phase III Randomized Trial Comparing Overall Survival After Photon Versus Proton Chemoradiotherapy for Inoperable Stage II-IIIB NSCLC.
photon beam radiation therapy; proton beam radiation therapy; paclitaxel; carboplatin; etoposide; cisplatin; quality-of-life assessment; questionnaire administration

Lung Neoplasms Clinical Trial using Radiation Concurrent Chemotherapy

Proton Collaborative Group - Recruiting 18 years or older.
- A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer.
Radiation Concurrent Chemotherapy

Non-Small Cell Lung Cancer Clinical Trial

Hoffmann-La Roche - Recruiting 65 years or older.
- Therapeutic Strategies Including Avastin as 1st Line Therapy in Elderly Patients Suffering From Advanced (IIIB/IV Stage) Non-squamous Non-small Cell Lung Cancer, in Routine Clinical Practice..

Cancer Clinical Trial using Dabrafenib; Trametinib

GlaxoSmithKline - Recruiting 18 years or older.
- A Phase II Study of the BRAF Inhibitor Dabrafenib as a Single Agent and in Combination With the MEK Inhibitor Trametinib in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer.
Dabrafenib; Trametinib

Non-small Cell Lung Cancer Clinical Trial using Stereotactic Body Radiotherapy (SBRT); Conventional Radiotherapy (CRT)

Ontario Clinical Oncology Group (OCOG) - Recruiting 18 years or older.
- A Randomized Trial of Medically-Inoperable Stage 1 Non-small Cell Lung Cancer Patients Comparing Stereotactic Body Radiotherapy Versus Conventional Radiotherapy.
Stereotactic Body Radiotherapy (SBRT); Conventional Radiotherapy (CRT)

Non-small Cell Lung Cancer Clinical Trial using Biopsy of the major carinal area; Biopsy of abnormal & suspicious areas of the bronchial tree; Evaluation of the tumor for DNA mutations; Bronchoalveolar Lavage (BAL) for cytokine analysis; Correlation of flow cytometric & RT PCR for TNM stage; Analysis of lymph nodes

University of Pittsburgh - Recruiting 18 years to 85 years.
- Detection of Genetic Markers of Lung Cancer Initiation and Progression.
Biopsy of the major carinal area; Biopsy of abnormal & suspicious areas of the bronchial tree; Evaluation of the tumor for DNA mutations; Bronchoalveolar Lavage (BAL) for cytokine analysis; Correlation of flow cytometric & RT PCR for TNM stage; Analysis of lymph nodes

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage I Clinical Trial using selumetinib; gemcitabine; cisplatin; carboplatin; pemetrexed

AstraZeneca - Recruiting 18 years or older.
- A Phase I, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Selumetinib (AZD6244; ARRY-142886) in Combination With First Line Chemotherapy Regimens in Patients With Non-Small Cell Lung Cancer (NSCLC).
selumetinib; gemcitabine; cisplatin; carboplatin; pemetrexed

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage I Clinical Trial using Selumetinib 75 mg; Docetaxel 75 mg/m2; Docetaxel 60 mg/m2; Placebo

AstraZeneca - Recruiting 18 years or older.
- A Phase II, Double-Blind, Randomised, Placebo-Controlled Study to Assess the Efficacy and Safety of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Combination With Docetaxel, Compared With Placebo in Combination With Docetaxel, in Patients Receiving Second Line Treatment for Locally Advanced or Metastatic Non Small Cell Lung Cancer (Stage IIIB - IV).
Selumetinib 75 mg; Docetaxel 75 mg/m2; Docetaxel 60 mg/m2; Placebo

Non Squamous Non Small Cell Lung Cancer Clinical Trial using OGX-427; Placebo

SCRI Development Innovations, LLC - Recruiting 18 years or older.
- Double-Blind Randomized Phase II Trial of Carboplatin and Pemetrexed With or Without OGX-427 in Patients With Previously Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer (The Spruce Clinical Trial).
OGX-427; Placebo

Adenocarcinoma of the Lung, Bronchoalveolar Cell Lung Cancer, Lar Clinical Trial using PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

City of Hope Medical Center - Recruiting 18 years or older.
- Phase I Trial of BKM120 in Combination With Carboplatin and Pemetrexed in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC).
PI3K inhibitor BKM120; pemetrexed disodium; carboplatin; laboratory biomarker analysis; pharmacological study; quality-of-life assessment

Non-Small Cell Lung Cancer Clinical Trial using Tarceva (erlotinib)

Albert Einstein College of Medicine of Yeshiva University - Recruiting 18 years or older.
- EValuation of Erlotinib as a Neoadjuvant Therapy in Stage III Non-small Cell Lung Cancer Patients With EGFR Mutations (EVENT Trial)..
Tarceva (erlotinib)

Recurrent Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lu Clinical Trial using trametinib; carboplatin; paclitaxel; intensity-modulated radiation therapy; 3-dimensional conformal radiation therapy; image-guided radiation therapy; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase 1 Study of Trametinib in Combination With Chemoradiation for KRAS Mutant Non-Small Cell Lung Cancer.
trametinib; carboplatin; paclitaxel; intensity-modulated radiation therapy; 3-dimensional conformal radiation therapy; image-guided radiation therapy; pharmacological study; laboratory biomarker analysis

Lung Cancer Clinical Trial using bevacizumab; emepepimut-S; carboplatin; cyclophosphamide; paclitaxel; radiation therapy

Eastern Cooperative Oncology Group - Recruiting 18 years or older.
- A Phase II Study of L-BLP25 and Bevacizumab in Unresectable Stage IIIA and IIIB Non-Squamous Non-Small Cell Lung Cancer After Definitive Chemoradiation.
bevacizumab; emepepimut-S; carboplatin; cyclophosphamide; paclitaxel; radiation therapy

Non-Small Cell Lung Carcinoma Clinical Trial using CV9202

CureVac GmbH - Recruiting 18 years or older.
- An Exploratory, Open-label Phase Ib Study of RNActiver-Derived Cancer Vaccine and Local Radiation as Consolidation and Maintenance Treatment in Patients With Stage IV NSCLC and a Response or Stable Disease After First-line Chemotherapy or Therapy With an EGFR Tyrosine Kinase Inhibitor.
CV9202

Non-Small Cell Lung Cancer Clinical Trial using erlotinib [Tarceva]; gemcitabine; cisplatin

Hoffmann-La Roche - Recruiting 18 years or older.
- A Multiple Center, Open-label, Randomized Phase III Study to Evaluate the Efficacy and Safety of Erlotinib (Tarceva) Versus Gemcitabine/Cisplatin as the First-line Treatment for Stage IIIB/IV NSCLC Patients With Mutations in the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor (EGFR) in Their Tumor.
erlotinib [Tarceva]; gemcitabine; cisplatin

Small Cell Lung Cancer Clinical Trial using Chloroquine, A-CQ 100

Maastricht Radiation Oncology - Recruiting 18 years or older.
- Chloroquine as an Anti-autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patients: A Phase 1 Trial.
Chloroquine, A-CQ 100

Non-small Cell Lung Cancer Clinical Trial using Induction chemotherapy and concurrent radiation; Consolidation: Radiation therapy to metastatic sites

Leo W. Jenkins Cancer Center - Recruiting 18 years or older.
- A Pilot Study Treating Patients With Minimal Stage IV Non-Small Cell Lung Cancer (NSCLC) With Curative Intent.
Induction chemotherapy and concurrent radiation; Consolidation: Radiation therapy to metastatic sites

Small Cell Lung Carcinoma Clinical Trial using Ipilimumab; Placebo matching Ipilimumab; Etoposide; Cisplatin; Carboplatin

Bristol-Myers Squibb - Recruiting 18 years or older.
- Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab Plus Etoposide/Platinum Versus Etoposide/Platinum in Subjects With Newly Diagnosed Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC).
Ipilimumab; Placebo matching Ipilimumab; Etoposide; Cisplatin; Carboplatin

Lung Cancer - Non Small Cell Clinical Trial using Ipilimumab; Placebo; Paclitaxel; Carboplatin

Bristol-Myers Squibb - Recruiting 18 years or older.
- Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin Versus Placebo in Addition to Paclitaxel and Carboplatin in Subjects With Stage IV/Recurrent Non Small Cell Lung Cancer (NSCLC).
Ipilimumab; Placebo; Paclitaxel; Carboplatin

Non-Small Cell Lung Cancer Clinical Trial using Custirsen + Docetaxel; Docetaxel

Teva Pharmaceutical Industries - Recruiting 18 years or older.
- A Multinational, Randomized, Open-Label Phase III Study of Custirsen (TV-1011/OGX-011) In Combination With Docetaxel Versus Docetaxel As A Second-Line Treatment In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer.
Custirsen + Docetaxel; Docetaxel

Extensive Stage Small Cell Lung Cancer, Limited Stage Small Cell Clinical Trial using technetium Tc 99m-labeled macroaggregated albumin; 99mTc-DTPA; single photon emission computed tomography; computed tomography

University of Washington - Recruiting 19 years or older.
- Pulmonary Functional Imaging for Radiation Treatment Planning for Lung Cancer.
technetium Tc 99m-labeled macroaggregated albumin; 99mTc-DTPA; single photon emission computed tomography; computed tomography

Squamous Non Small Cell Lung Cancer Clinical Trial using Necitumumab; Paclitaxel; Carboplatin

Eli Lilly and Company - Recruiting 18 years or older.
- A Randomized, Multicenter, Open-Label, Phase 2 Study of Paclitaxel-Carboplatin Chemotherapy Plus Necitumumab (IMC-11F8) Versus Paclitaxel-Carboplatin Chemotherapy Alone in the First-Line Treatment of Patients With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC).
Necitumumab; Paclitaxel; Carboplatin

Extensive Stage Small Cell Lung Cancer Clinical Trial using bioelectric impedance analysis

Comprehensive Cancer Center of Wake Forest University - Recruiting 18 years or older.
- Investigating the Prognostic Importance of Bioelectrical Impedance Phase Angle in Adults Treated for Small Cell Lung Cancer.
bioelectric impedance analysis

Squamous Non-small Cell Lung Cancer Clinical Trial using Necitumumab; Gemcitabine; Cisplatin

Eli Lilly and Company - Recruiting 20 years or older.
- An Open-Label, Multicenter, Phase 1b/2 Study to Evaluate Necitumumab in Combination With Gemcitabine and Cisplatin in the First-Line Treatment of Patients With Advanced (Stage IV) Squamous Non-Small Cell Lung Cancer (NSCLC).
Necitumumab; Gemcitabine; Cisplatin

Non-small Cell Lung Cancer (NSCLC), Stage IV NSCLC, or Metastatic Clinical Trial using Cabazitaxel-XRP6258

University of Alabama at Birmingham - Recruiting 19 years or older.
- Phase II Study of a Novel Taxane (Cabazitaxel-XRP6258) in Previously Treated Advanced Non-Small Cell Lung Cancer (NSCLC) Patients.
Cabazitaxel-XRP6258

Non Small Cell Lung Cancer Clinical Trial

Maastricht Radiation Oncology - Recruiting 18 years or older.
- In Silico Clinical Trial, Comparing State of the Art Photon Modalities With Proton and 12C-ion Therapy for Stage I NSCLC: A Multicentric ROCOCO Planning Study Based on a Reference Dataset of Patients.

Non-small Cell Lung Cancer(NSCLC) Clinical Trial using erlotinib; docetaxel

National Taiwan University Hospital - Recruiting 18 years or older.
- An Open-label, Randomized, Phase II Study of Erlotinib Monotherapy Versus Docetaxel and Cisplatin as Neoadjuvant Therapy in Patients of Stage IIIA Lung Adenocarcinoma With Epidermal Growth Factor Receptor Gene Mutation..
erlotinib; docetaxel

Non-small Cell Lung Cancer Metastatic, or Non-small Cell Lung Can Clinical Trial using PET/CT

National Cancer Institute, Naples - Recruiting 18 years or older.
- Study of the Role of Metabolic Response Measured by PET/CT Scan After 1 Cycle of Chemotherapy in Patients With Advanced Non Small Cell Lung Cancer (NSCLC).
PET/CT

Lung Cancer Clinical Trial using bexarotene; capecitabine; carboplatin; cisplatin; docetaxel; tretinoin

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Phase II Trial of Bexarotene (Targretin) Capsules With Tretinoin and Chemotherapy in Patients With Advanced Non-small-cell Lung Cancer.
bexarotene; capecitabine; carboplatin; cisplatin; docetaxel; tretinoin

Non-Small Cell Lung Cancer Clinical Trial using erlotinib [Tarceva]; Placebo; Onartuzumab [MetMAb]

Hoffmann-La Roche - Recruiting 18 years or older.
- A RANDOMIZED, PHASE III, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF ONARTUZUMAB (MetMAb) IN COMBINATION WITH ERLOTINIB AS SECOND- OR THIRD-LINE TREATMENT FOR PATIENTS WITH MET-POSITIVE INCURABLE STAGE IIIB/IV NON-SMALL CELL LUNG CANCER.
erlotinib [Tarceva]; Placebo; Onartuzumab [MetMAb]

Stage IV Non-small Cell Lung Cancer Clinical Trial using erlotinib; bevacizumab; laboratory biomarker analysis

Academic and Community Cancer Research United - Recruiting 18 years or older.
- A Randomized Phase II Trial of Erlotinib Alone or In Combination With Bevacizumab in Patients With Non-Small Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations.
erlotinib; bevacizumab; laboratory biomarker analysis

Lung Cancer Clinical Trial using LDE225, Etoposide and Cisplatin

Memorial Sloan-Kettering Cancer Center - Recruiting 18 years or older.
- A Phase I Trial of the Combination of the Hedgehog Inhibitor, LDE225, With Etoposide and Cisplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC).
LDE225, Etoposide and Cisplatin

Non-small Cell Lung Cancer Metastatic, or Non-small Cell Lung Can Clinical Trial using Gemcitabine; Pemetrexed; Cisplatin

National Cancer Institute, Naples - Recruiting 70 years or older.
- A Factorial Study Comparing Pemetrexed With Gemcitabine and Testing the Efficacy of the Addition of Cisplatin in Elderly Patients With Non Squamous Advanced, Metastatic or Recurrent NSCLC..
Gemcitabine; Pemetrexed; Cisplatin

Recurrent Non-small Cell Lung Cancer, Stage IIIA Non-small Cell L Clinical Trial using therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Roswell Park Cancer Institute - Recruiting 18 years or older.
- A Pilot Study of Stereotactic Body Radiation Therapy (SBRT) After TEMLA for Stage III and IV (Oligometastatic) Non-Small Cell Lung Cancer.
therapeutic lymphadenectomy; stereotactic body radiation therapy; quality-of-life assessment

Non Small Cell Lung Cancer Clinical Trial using Everolimus; Pemetrexed; Carboplatin; Bevacizumab

Cancer Research and Biostatistics Clinical Trials Consortium - Recruiting 18 years or older.
- Phase I Dose Escalation Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab in Stage IV Non-Squamous Non-Small Cell Lung Cancer.
Everolimus; Pemetrexed; Carboplatin; Bevacizumab

Non Small Cell Lung Cancer Clinical Trial using Afatinib

Massachusetts General Hospital - Recruiting 18 years or older.
- Randomized Phase II Study Comparing Concise Versus Prolonged Afatinib as Adjuvant Therapy for Patients With Resected Stage I-III NSCLC With EGFR Mutation.
Afatinib

Lung Cancer Clinical Trial using EBUS-TBNA

M.D. Anderson Cancer Center - Recruiting 18 years or older.
- Diagnostic Utility of Endobronchial Ultrasound Guided Mediastinal Lymph Node Sampling in Clinical Stage I and II Non Small Cell Lung Cancer.
EBUS-TBNA

Non-Small Cell Lung Cancer Clinical Trial using Peripherally located lung tumor; Centrally located lung tumor

University of Florida - Recruiting 18 years or older.
- Hypofractionated, Image-Guided Radiation Therapy With Proton Therapy for Stage I Non-Small Cell Lung Cancer.
Peripherally located lung tumor; Centrally located lung tumor

Patients Must Have Histologically or Cytologically Confirmed Non- Clinical Trial using Paclitaxel, Carboplatin, Bevacizumab, and Metformin; Paclictaxl, Carboplatin, and Bevcizumab.

Sidney Kimmel Comprehensive Cancer Center - Recruiting 18 years or older.
- A Randomized Phase II Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Previously Untreated Advanced/Metastatic Pulmonary Adenocarcinoma.
Paclitaxel, Carboplatin, Bevacizumab, and Metformin; Paclictaxl, Carboplatin, and Bevcizumab.

Stage IV Small Cell Lung Cancer Clinical Trial using OMP-59R5; Etoposide; Placebo; Cisplatin

OncoMed Pharmaceuticals, Inc. - Recruiting 18 years to 90 years.
- A Phase 1b/2 Study of OMP-59R5 in Combination With Etoposide and Cisplatin in Subjects With Untreated Extensive Stage Small Cell Lung Cancer (PINNACLE).
OMP-59R5; Etoposide; Placebo; Cisplatin

Recurrent Non-small Cell Lung Cancer, Stage IIIA Non-small Cell L Clinical Trial using entinostat; azacitidine; pharmacological study; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase I/II Study of Entinostat in Combination With 5-Azacytidine in Patients With Recurrent Advanced Non-Small Cell Lung Cancer.
entinostat; azacitidine; pharmacological study; laboratory biomarker analysis

Recurrent Non-small Cell Lung Cancer, or Stage IV Non-small Cell Clinical Trial using paclitaxel albumin-stabilized nanoparticle formulation; laboratory biomarker analysis

Fred Hutchinson Cancer Research Center - Recruiting 18 years or older.
- A Phase II Study of Weekly ABRAXANEr (Nab-paclitaxel) for Patients With Advanced NSCLC With EGFR Mutations Following Front-line Therapy With EGFR Tyrosine Kinase Inhibitors.
paclitaxel albumin-stabilized nanoparticle formulation; laboratory biomarker analysis

Stage I-III Small Cell Lung Cancer Clinical Trial using Radiotherapy

Maastricht Radiation Oncology - Recruiting 18 years or older.
- Concurrent Chemo-radiotherapy With IMRT for Stage I-III Small Cell Lung Cancer.
Radiotherapy

Lung Cancer Clinical Trial using carboplatin; cisplatin; gemcitabine hydrochloride

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A British Thoracic Oncology Group Phase III Trial of Gemcitabine Plus Cisplatin at 80mg/m Versus Gemcitabine Plus Carboplatin At 50 mg/m Versus Gemcitabine Plus Carboplatin AUC 6 in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC).
carboplatin; cisplatin; gemcitabine hydrochloride

Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer, Large Clinical Trial using hypofractionated radiation therapy; laboratory biomarker analysis; image-guided radiation therapy; carboplatin; paclitaxel; stereotactic body radiation therapy

Jonsson Comprehensive Cancer Center - Recruiting 18 years or older.
- Image-Guided Hypofractionated Radiotherapy With Stereotactic Boost and Chemotherapy for Inoperable Stage II-III Non-Small Cell Lung Cancer.
hypofractionated radiation therapy; laboratory biomarker analysis; image-guided radiation therapy; carboplatin; paclitaxel; stereotactic body radiation therapy

Lung Cancer Clinical Trial using carboplatin; nitroglycerin; paclitaxel

National Cancer Institute (NCI) - Recruiting 40 years to 80 years.
- A Phase II, Multinational and Multicenter, Randomized, Controlled Study of Paclitaxel and Carboplatin With vs Without Nitroglycerin in Patients With Untreated Advanced Non-small Cell Lung Cancer.
carboplatin; nitroglycerin; paclitaxel

Lung Cancer Clinical Trial using cisplatin; gemcitabine hydrochloride; adjuvant therapy; conventional surgery; neoadjuvant therapy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Randomized Phase II Study of Preoperative Versus Postoperative Gemcitabine and Cisplatin for Patients With Stage IB-II Non-Small Cell Lung Cancer.
cisplatin; gemcitabine hydrochloride; adjuvant therapy; conventional surgery; neoadjuvant therapy

Stage III Non-small Cell Lung Cancer Clinical Trial using Chemotherapy; ERBITUX; Radiotherapy

Intergroupe Francophone de Cancerologie Thoracique - Recruiting 18 years to 70 years.
- Phase II Study of Pemetrexed + Cetuximab + Cisplatin With Concurrent Chemoradiotherapy in Stage III Non-small Cell Lung Cancer (NSCLC).
Chemotherapy; ERBITUX; Radiotherapy

Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Clinical Trial using breath test; laboratory biomarker analysis

Fox Chase Cancer Center - Recruiting 18 years or older.
- A Single-center Study to Evaluate the Feasibility of a Novel NA-NOSE for Monitoring Response to and Detecting Recurrence After Surgery or Radiation in Early Stage Lung Cancer.
breath test; laboratory biomarker analysis

NSCLC, EGFR Gene Amplification, Advanced Cancer, Stage IIIB NSCLC Clinical Trial using Gefitinib and Metformin; Gefitinib and placebo

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University - Recruiting 18 years to 75 years.
- A Phase II, Randomized, Placebo Controlled Study to Evaluate the Efficacy of the Combination of Gefitinib and Metformin in Patients With Locally Advanced and Metastatic Non-Small-Cell-Lung-Cancer.
Gefitinib and Metformin; Gefitinib and placebo

Lung Cancer Clinical Trial using Pazopanib

UNC Lineberger Comprehensive Cancer Center - Recruiting 18 years or older.
- A Multi-Center Open Label Phase II Study of Pazopanib in Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer After Progression on First Line Therapy Containing Bevacizumab.
Pazopanib

Carcinoma, Non-Small-Cell Lung Clinical Trial using Astagalus-based Formula: Qingshu-Yiqi-Tang

Chang Gung Memorial Hospital - Recruiting 18 years to 75 years.
- Efficacy Study of Chinese Medicine on Modulating Immune Alterations in Advanced Stage, Non-small Cell Lung Cancer Patients Receiving 1st Line Doublet Chemotherapy and 2nd Line Target Therapy.
Astagalus-based Formula: Qingshu-Yiqi-Tang

Lung Cancer Clinical Trial using therapeutic thoracoscopy; videothoracoscopy

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Phase III Randomized Trial of Lobectomy Versus Sublobar Resection for Small (ó 2 CM) Peripheral Non-Small Cell Lung Cancer.
therapeutic thoracoscopy; videothoracoscopy

Non-small Cell Lung Cancer Metastatic, or Small Cell Lung Carcino Clinical Trial using therapeutic interventions

Vanderbilt-Ingram Cancer Center - Recruiting 18 years or older.
- Collaborative Advanced Stage Tissue Lung Cancer (CASTLE) Network.
therapeutic interventions

Malignant Pleural Effusion Clinical Trial using Bevacizumab; Cisplatin

Chinese PLA General Hospital - Recruiting 18 years to 60 years.
- Open-labled, Randomized, Multicenter Phase III Study of Adjuvant Chemotherapy Comparing Bevacizumab Plus Cisplatin With Cisplatin Regimen in Malignant Pleural Effusion of Advanced Stage Non-Small-Cell Lung Cancer Patients.
Bevacizumab; Cisplatin

Non-small Cell Lung Cancer Stage IIIB, or Toxicity Due to Chemoth Clinical Trial using chemotherapy & WBH

Xijing Hospital - Recruiting 18 years to 75 years.
- A Randomized Contrasted Polycentric Clinical Study About Chemotherapy Combined With Whole-body Hyperthermia(WBH)to Treat Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC).
chemotherapy & WBH

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous, or Carcinoma Clinical Trial using Docetaxel; Oxaliplatin

Korean South West Oncology Group - Recruiting 18 years or older.
- A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line Treatment.
Docetaxel; Oxaliplatin

Thoracic Neoplasms, or Non-small Cell Lung Cancer Clinical Trial using 3D conform radiotherapy

Chinese Academy of Medical Sciences - Recruiting 18 years to 70 years.
- Phase III Comparison of Postoperative 3D Conform Radiotherapy After Chemotherapy and Chemotherapy Alone in Patients With Completely Resected Stage IIIA(N2) Non-small Cell Lung Cancer.
3D conform radiotherapy

Non Small Cell Lung Cancer Clinical Trial using carboplatin paclitaxel bevacizumab; Standard treatment plus nitroglycerin

Dutch Society of Physicians for Pulmonology and Tuberculosis - Recruiting 18 years or older.
- A Randomized Phase II Study of Paclitaxel-carboplatin-bevacizumab With or Without Nitroglycerin Patches in Patients With Stage IV Non-squamous-non-small Cell Lung Cancer: NVALT12.
carboplatin paclitaxel bevacizumab; Standard treatment plus nitroglycerin

NSCLC, or Non Small Cell Lung Cancer Clinical Trial using Cesium-131 Brachytherapy Seed

IsoRay Medical, Inc. - Recruiting N/A or older.
- Outcome Study of Cesium-131 Brachytherapy Following Sub-Lobar Resection for Early Stage NSCLC.
Cesium-131 Brachytherapy Seed

Lung Cancer Clinical Trial using erlotinib hydrochloride; sorafenib tosylate; DNA analysis; mutation analysis; polymerase chain reaction; protein analysis; protein expression analysis; immunohistochemistry staining method; laboratory biomarker analysis

National Cancer Institute (NCI) - Recruiting 18 years or older.
- A Multicenter, Open-label, Phase II Study of Sorafenib in Combination With Erlotinib in Non-small Cell Lung Cancer (NSCLC) Refractory to One or Two Prior Chemotherapy Regimens.
erlotinib hydrochloride; sorafenib tosylate; DNA analysis; mutation analysis; polymerase chain reaction; protein analysis; protein expression analysis; immunohistochemistry staining method; laboratory biomarker analysis

Lung Cancer Clinical Trial using cisplatin; docetaxel; quality-of-life assessment; radiation therapy; stereotactic radiosurgery

National Cancer Institute (NCI) - Recruiting 18 years or older.
- Study of Doses Escalation on Efficacy on Cyberknife After Docetaxel-Cisplatin Concomitant Radiotherapy for Non Small Cells Lung Cancer Stage III.
cisplatin; docetaxel; quality-of-life assessment; radiation therapy; stereotactic radiosurgery

Lung Cancer Clinical Trial using cisplatin; etoposide; irinotecan hydrochloride; radiation therapy

National Cancer Institute (NCI) - Recruiting 18 years to 75 years.
- Phase II Trial Irinotecan and Cisplatin Induction Chemotherapy Followed by Radiotherapy Concurrently With Etoposide/Cisplatin in Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer.
cisplatin; etoposide; irinotecan hydrochloride; radiation therapy

Small Cell Lung Cancer Clinical Trial using Irinotecan hydrochloride; Cisplatin; Krestin

University of Toyama - Recruiting 20 years to 74 years.
- Feasibility Study for Multicenter Randomized Controlled Phase III Clinical Trial of Cisplatin + Irinotecan Therapy and Cisplatin + Irinotecan + Krestin Therapy for Extensive-Stage Disease (ED) Small Cell Lung Cancer.
Irinotecan hydrochloride; Cisplatin; Krestin

Lung Cancer Clinical Trial using gemicitabine 1000mg/m2, day1 and day 8, every 3 week, 6; UFT 250mg/m2, daily for 1 year

West Japan Thoracic Oncology Group - Recruiting 20 years to 75 years.
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gemicitabine 1000mg/m2, day1 and day 8, every 3 week, 6; UFT 250mg/m2, daily for 1 year