60 results found.

Traumatic Brain Injury, or Healthy Clinical Trial using PET

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- PET Imaging of Translocator Protein in Subjects With Traumatic Brain Injury.
PET

Traumatic Brain Injury With Brief Loss of Consciousness, or Post- Clinical Trial using Hyperbaric oxygen (HBO2) at 1.5 atms; Sham control 1.2 atms

U.S. Army Medical Research and Materiel Command - Recruiting 18 years to 65 years.
- Brain Injury and Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms After Mild Traumatic Brain Injury (BIMA) Protocol.
Hyperbaric oxygen (HBO2) at 1.5 atms; Sham control 1.2 atms

Traumatic Brain Injury, TBI, or ADHD Clinical Trial using Methylphenidate; Placebo

Children's Hospital Medical Center, Cincinnati - Recruiting 6 years to 17 years.
- Efficacy of Methylphenidate for Management of Long-Term Attention Problems After Pediatric Traumatic Brain Injury (TBI).
Methylphenidate; Placebo

Traumatic Brain Injury Clinical Trial using Oxycyte; Normal Saline

Oxygen Biotherapeutics, Inc. - Recruiting 18 years to 70 years.
- A Randomized, Placebo Controlled, Double-Blind, Single Dose, Dose Escalation Study to Evaluate the Safety and Tolerability of Oxycyte in Patients With Severe Non-Penetrating Traumatic Brain Injury.
Oxycyte; Normal Saline

Brain Injuries Clinical Trial using NNZ-2566

Neuren Pharmaceuticals Limited - Recruiting 18 years to 70 years.
- A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of NNZ-2566 in Patients With Traumatic Brain Injury.
NNZ-2566

Traumatic Brain Injury, Stroke, Headache, or PTSD Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 40 years.
- Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury.

Traumatic Brain Injury Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury.

Traumatic Brain Injury, or fMRI Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 70 years.
- The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans.

Traumatic Brain Injury Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters.

Traumatic Brain Injury Clinical Trial using Exercise - Low-intensity exercise; Exercise - High-intensity exercise

National Institutes of Health Clinical Center (CC) - Recruiting 18 years to 45 years.
- Acute Effects of Exercise on Memory in Healthy and Brain-Injured Individuals.
Exercise - Low-intensity exercise; Exercise - High-intensity exercise

Fatigue, or Traumatic Brain Injury Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Fatigue and Amotivation Following Mild Traumatic Brain Injury and Their Influence on Service Member Community Reintegration.

Traumatic Brain Injury Clinical Trial using Buspirone; Placebo

Indiana University - Recruiting 18 years to 70 years.
- Brain Research in Aggression and Irritability Network (BRAIN): Building Evidence-Based Approaches to Managing Traumatic Brain Injury.
Buspirone; Placebo

Post Traumatic Stress Disorder,, or Mild Traumatic Brain Injury, Clinical Trial using GOALS (Goal-Oriented Attentional Regulation); EDU (Brain Health Education)

Department of Veterans Affairs - Recruiting 18 years to 65 years.
- Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI.
GOALS (Goal-Oriented Attentional Regulation); EDU (Brain Health Education)

Tinnitus Clinical Trial using Telephone Tinnitus Education; Wait List Control

Department of Veterans Affairs - Recruiting 18 years or older.
- Telehealth Tinnitus Intervention for Patients With TBI.
Telephone Tinnitus Education; Wait List Control

Traumatic Brain Injury Clinical Trial using Intention; Motivation

Albert Einstein Healthcare Network - Recruiting 18 years or older.
- Use of SMS Messaging to Promote Emotional Health for People With Traumatic Brain Injury: A Randomized Controlled Trial.
Intention; Motivation

Brain Injuries Clinical Trial using NNZ-2566

Neuren Pharmaceuticals Limited - Recruiting 16 years to 75 years.
- A Randomized, Double-Blind, Placebo-Controlled, Study of NNZ-2566 in Patients With Traumatic Brain Injury (TBI) Conducted Under an Exception From Informed Consent (EFIC).
NNZ-2566

Traumatic Brain Injury Clinical Trial

University of Washington - Recruiting 13 years or older.
- Managing Severe Traumatic Brain Injury (TBI) Without Intracranial Pressure Monitoring (ICP)- Guidelines Development and Testing.

Traumatic Brain Injury, or Post-traumatic Stress Disorder Clinical Trial

International Hyperbaric Medical Foundation - Recruiting 18 years to 65 years.
- Multicenter Observational Study of Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post-Concussion Syndrome (PCS) and/or TBI/Post-Traumatic Stress Disorder (PTSD).

Traumatic Brain Injury, or Cognitive Symptoms Clinical Trial using Cognitive Intervention; Educational intervention

Department of Veterans Affairs - Recruiting 21 years to 50 years.
- Cognitive Rehabilitation of Blast-induced Traumatic Brain Injury.
Cognitive Intervention; Educational intervention

Brain Injuries, or Craniocerebral Trauma Clinical Trial using Long-term mild hypothermia; Normothermia

RenJi Hospital - Recruiting 18 years to 65 years.
- A Multi-center, Randomized, Controlled Trial to Evaluate the Efficacy and Safety of Long-term Mild Hypothermia in Adult Patients With Severe Traumatic Brain Injury.
Long-term mild hypothermia; Normothermia

Traumatic Brain Injury Clinical Trial using autologous bone marrow mononuclear cells

The University of Texas Health Science Center, Houston - Recruiting 5 years to 17 years.
- Phase 2 Trial of Pediatric Autologous Bone Marrow Mononuclear Cells (BMMNCs) for Severe Traumatic Brain Injury (TBI).
autologous bone marrow mononuclear cells

Traumatic Brain Injury, Balance Disorders, or Attention Deficits Clinical Trial using gaming therapy (Xbox); Dynamic balance platform (Biodex)

University Hospital of Ferrara - Recruiting 18 years to 70 years.
- 'Feasibility and Efficacy of Virtual Reality With Xbox Kinect in the Rehabilitation of Cronic Traumatic Brain Injuries: a Randomized Controlled Trial'..
gaming therapy (Xbox); Dynamic balance platform (Biodex)

Exercise, Fatigue, Physical Fitness, or Traumatic Brain Injury Clinical Trial using Rehabilitation

National Institutes of Health Clinical Center (CC) - Recruiting 21 years to 45 years.
- Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients With Traumatic Brain Injury.
Rehabilitation

Concussion, Post-concussion Syndrome, Mild Traumatic Brain Injury Clinical Trial using Aerobic Training Intervention; Stretching Intervention

Children's Hospital Medical Center, Cincinnati - Recruiting 12 years to 17 years.
- Aerobic Training for Management of Post-Concussion Syndrome in Adolescents.
Aerobic Training Intervention; Stretching Intervention

Traumatic Brain Injury, Cerebrovascular Accident (CVA), or Acquir Clinical Trial using Conventional rehabilitation.; Novel rehabilitation approach

Baycrest - Recruiting 18 years or older.
- Managing the Dysexecutive Syndrome Following Traumatic Brain Injury: An Ecologically Valid Rehabilitation Approach.
Conventional rehabilitation.; Novel rehabilitation approach

Sport-related Concussion, Concussion, or Mild Traumatic Brain Inj Clinical Trial using Active Rehabilitation Program; Treatment-as-usual (TAU)

University of British Columbia - Recruiting 14 years to 18 years.
- Active Rehabilitation for Slow to Recover Adolescents Following Sport-Related Concussion: A Randomized Control Trial.
Active Rehabilitation Program; Treatment-as-usual (TAU)

Traumatic Brain Injury Clinical Trial using Autologous bone marrow mononuclear cell transplantation

Neurogen Brain and Spine Institute - Recruiting 6 Months to 65 years.
- Open Label Study of Autologous Bone Marrow Mononuclear Cells in Traumatic Brain Injury.
Autologous bone marrow mononuclear cell transplantation

Traumatic Brain Injury Clinical Trial using valproate acid

Xijing Hospital - Recruiting 16 years to 65 years.
- Clinical Study on the Neuroprotection and Epilepsy Prevention of Valproate Acid Administered After Severe Traumatic Brain Injury.
valproate acid

Concussion, Mild, Post-Concussion Symptoms, or Sleep Problems Clinical Trial using wavelength-1 bright light

Mclean Hospital - Recruiting 18 years to 50 years.
- Effects of Bright Light Therapy of Sleep, Cognition, Brain Function, and Neurochemistry in Mild Traumatic Brain Injury.
wavelength-1 bright light

Traumatic Brain Injury Clinical Trial using The Veterans' In-home Program

Philadelphia Veterans Affairs Medical Center - Recruiting 18 years or older.
- Evaluation of the Veterans' In-home Programs for Veterans With TBI and Families.
The Veterans' In-home Program

Traumatic Brain Injury Clinical Trial using Blood/saliva sampling

The University of Texas Health Science Center, Houston - Recruiting 18 years to 70 years.
- A Pilot Study to Identify Biomarkers Associated With Chronic TBI.
Blood/saliva sampling

Traumatic Brain Injury Clinical Trial using Individualized Scheduled Telephone Support (ISTS); Usual Care (UC)

INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium - Recruiting 18 years or older.
- The Effect of Telephone Follow up on Outcome for Service Members With Mild TBI/PTSD.
Individualized Scheduled Telephone Support (ISTS); Usual Care (UC)

Post-Traumatic Stress Disorder Clinical Trial using Tramadol; Placebo

INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium - Recruiting 21 years to 55 years.
- A Double-Blind, Placebo-Controlled, Flexible-Dose Pilot Clinical Trial of Once-Daily Extended-Release Tramadol for the Treatment of PTSD.
Tramadol; Placebo

Brain Injuries, Traumatic Clinical Trial

INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium - Recruiting 18 years to 60 years.
- Reliability and Initial Validation of the INTRuST Structured Assessment For Evaluation of TBI (SAFE-TBI).

Traumatic Brain Injury Clinical Trial using Cerebrolysin; 0.9% NaCl, saline

Ever Neuro Pharma GmbH - Recruiting 18 years to 60 years.
- A Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin in Patients With Traumatic Brain Injury.
Cerebrolysin; 0.9% NaCl, saline

Mild Cognitive Impairment, Alzheimer's Disease, or Traumatic Brai Clinical Trial using explicit memory training; implicit memory training

Department of Veterans Affairs - Recruiting 18 years to 88 years.
- Behavioral and Neuroimaging Changes After Cognitive Rehab in TBI and MCI.
explicit memory training; implicit memory training

TBI, or Attention Deficits Clinical Trial using GVS; Sham GVS; Armeo Spring; Computer-based attention games

Spaulding Rehabilitation Hospital - Recruiting 18 years to 70 years.
- Combining Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors With Attentional Deficits.
GVS; Sham GVS; Armeo Spring; Computer-based attention games

Traumatic Brain Injury Clinical Trial using autologous bone marrow mononuclear cells

The University of Texas Health Science Center, Houston - Recruiting 18 years to 55 years.
- Treatment of Severe Adult Traumatic Brain Injury Using Bone Marrow Mononuclear Cells.
autologous bone marrow mononuclear cells

Traumatic Brain Injury Clinical Trial

ElMindA Ltd - Recruiting 14 years to 27 years.
- Comparison of Brain Network Activation Analysis (BNAT) Using Evoked Response Potentials, Clinical Symptoms and Neuro-cognitive Performance and Symptoms in Concussed Children, Young Adults and Matched Controls.

Traumatic Brain Injury, or Children Clinical Trial using Dexmedetomidine

University of Sao Paulo - Recruiting 1 Month to 15 years.
- Intranasal Dexmedetomidine Sedation for Pediatric Computerized Tomography Imaging.
Dexmedetomidine

Mild Traumatic Brain Injury Clinical Trial using SWIFT; SWIFT-Acute

University of Washington - Recruiting 18 years or older.
- Social Work Intervention for Adults With Mild Traumatic Brain Injury: SWIFT Pilot Study.
SWIFT; SWIFT-Acute

Brain Injuries, or Post-Traumatic Headache Clinical Trial using Amitriptyline

University of Washington - Recruiting 18 years to 55 years.
- Amitriptyline to Prevent Headache After Traumatic Brain Injury.
Amitriptyline

Traumatic Brain Injury, or Posttraumatic Stress Disorder Clinical Trial using Cognitive Rehabilitation Intervention; Cognitive Rehabilitation Control Intervention

University of North Carolina, Chapel Hill - Recruiting 18 years to 65 years.
- Neural Markers and Rehabilitation of Executive Functioning in Veterans With TBI and PTSD.
Cognitive Rehabilitation Intervention; Cognitive Rehabilitation Control Intervention

Growth Hormone Deficiency, or Traumatic Brain Injury Clinical Trial using Human Growth Hormone; Placebo

The University of Texas, Galveston - Recruiting 21 years or older.
- Anterior Pituitary Hormone Replacement in Traumatic Brain Injury.
Human Growth Hormone; Placebo

Traumatic Brain Injury Clinical Trial using Telephone-Based Goal Management Training; Telephone-Based Attention-Control

Vanderbilt University - Recruiting 21 years to 80 years.
- .
Telephone-Based Goal Management Training; Telephone-Based Attention-Control

Traumatic and/or Non-traumatic Brain Injury Clinical Trial

Sheba Medical Center - Recruiting 18 years to 85 years.
- The Reproducibility and Special Features of Hemiparetic Gait in People With Acquired Brain Injury (ABI) Assessed With an Instrumented Treadmill (Zebris).

TBI (Traumatic Brain Injury), or Acute Brain Injuries Clinical Trial

St. Michael's Hospital, Toronto - Recruiting 18 years to 80 years.
- Observational Study of Cerebral Tissue Oxygen Saturation During Blood Transfusion in Severe Traumatic Brain Injured Patients.

Traumatic Brain Injury, Weaning Failure, or Mechanical Ventilatio Clinical Trial using Predictive indexes of weaning from mechanical ventilation

Federal University of Uberlandia - Recruiting 18 years or older.
- Evaluation of Integrated Predictive Index of Weaning From Mechanical Ventilation in Patients With Traumatic Brain Injury.
Predictive indexes of weaning from mechanical ventilation

Traumatic Brain Injury Clinical Trial using Computerized clinical decision support

Columbia University - Recruiting N/A or older.
- Implementation of the Pediatric Emergency Care Applied Research Network (PECARN) Traumatic Brain Injury Prediction Rules Using Computerized Clinical Decision Support: An Interrupted Time Series Trial.
Computerized clinical decision support

Minimally Conscious States Due to Traumatic Brain Injury, or Pers Clinical Trial using Vagus nerve stimulation;; No stimulation

VA New York Harbor Healthcare System - Recruiting 18 years to 60 years.
- Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury.
Vagus nerve stimulation;; No stimulation

Depression, or Traumatic Brain Injury Clinical Trial using Mindfulness-Based Cognitive Therapy

Lakehead University - Recruiting 18 years or older.
- A Multi-site, Randomized, Controlled Trial of a Mindfulness-based Cognitive Therapy Intervention for Treating Depression in a Traumatic Brain Injury Population..
Mindfulness-Based Cognitive Therapy

Traumatic Brain Injury Clinical Trial using Propranolol

Cedars-Sinai Medical Center - Recruiting 18 years or older.
- A Phase II, Dose Escalation, Single Center Study on the Effects of Early Propranolol on Heart Rate, Blood Pressure, and Cerebral Perfusion Pressure in Subjects Who Present With Moderate to Severe Traumatic Brain Injury..
Propranolol

Mild to Moderate Traumatic Brain Injury Clinical Trial using Interactive metronome

Henry M. Jackson Foundation for the Advancement of Military Medicine - Recruiting 18 years to 55 years.
- 'A Randomized, Controlled, Trial of Interactive Metronome Technology for Remediation of Cognitive Difficulties Following Blast-Related Traumatic Brain Injury'.
Interactive metronome

Brain Injuries Clinical Trial using Problem-based telephone counseling; No Intervention

University of Washington - Recruiting 16 years or older.
- Modular Scheduled Telephone Intervention for Caregivers of Persons With Traumatic Brain Injury: A Randomized Controlled Trial.
Problem-based telephone counseling; No Intervention

Traumatic Brain Injury Clinical Trial

Kessler Foundation - Recruiting 18 years to 70 years.
- The Relationship Between Fatigue, Sleep Disorders and Endocrine Abnormalities Following Traumatic Brain Injury.

Subarachnoid Hemorrhage, Traumatic Brain Injury, or Intracranial Clinical Trial using Insulin (Actrapid)

University of Roma La Sapienza - Recruiting 18 years to 80 years.
- Effects of Intensive Insulin Therapy on Mortality, Morbidity and Long Term Neurologic Outcome in Neurosurgical Intensive Care Patients.
Insulin (Actrapid)

Neurologic Injury, or Traumatic Brain Injury Clinical Trial using Enteral glutamine powder; placebo

University of Wisconsin, Madison - Recruiting 18 years to 75 years.
- Randomized, Placebo-Controlled Clinical Trial of Enteral Glutamine Supplementation in Neurologically-Injured Patients.
Enteral glutamine powder; placebo