42 results found.

Tuberculosis, or HIV Infections Clinical Trial using Rifapentine (RPT); Isoniazid (INH); Pyridoxine (Vitamin B6)

National Institute of Allergy and Infectious Diseases (NIAID) - Recruiting 13 years or older.
- Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection.
Rifapentine (RPT); Isoniazid (INH); Pyridoxine (Vitamin B6)

Tuberculosis Clinical Trial using Enhanced TB IC Package

Centers for Disease Control and Prevention - Recruiting 18 years to 45 years.
- Evaluation of an Enhanced Tuberculosis Infection Control Intervention in Healthcare Facilities in Vietnam and Thailand.
Enhanced TB IC Package

Tuberculosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 2 years or older.
- Training Protocol on the Natural History of Tuberculosis.

Latent Tuberculosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 20 years to 60 years.
- Risk Stratification in Latent Tuberculosis: PET/CT Findings in TB Contacts.

Tuberculosis Clinical Trial using RIF; INH; PZA; KM; MXF

National Institutes of Health Clinical Center (CC) - Recruiting 20 years or older.
- Pharmacokinetics of Standard First and Second Line Anti-TB Drugs in the Lung and Lesions of Subjects Elected for Resection Surgery.
RIF; INH; PZA; KM; MXF

Tuberculosis, HIV, or IRIS Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 18 years or older.
- Transcriptional Signature of HIV And TB Co-Infection.

Lung Cancer, Tuberculosis, Bronchiectasis, Pneumonia, Acute Bronc Clinical Trial using Chest X-ray; computed tomography of the chest; Bronchoscopy

University of Milan - Recruiting 18 years or older.
- Multicenter, Prospective, Observational Study on Epidemiology and Diagnosis of Haemoptysis.
Chest X-ray; computed tomography of the chest; Bronchoscopy

Tuberculosis Clinical Trial using C-Tb; 2 T.U. Tuberculin PPD RT 23 SSI

Statens Serum Institut - Recruiting N/A to 65 years.
- A Phase III Trial in Subjects Suspected to Have Tuberculosis, Comparing the Diagnostic Performance of C-Tb to QuantiFERONr-TB Gold In-Tube, in Combination With a Double Blind Randomized Split Body Safety Assessment of C-Tb Versus 2 T.U. Tuberculin PPD RT23 SSI (PPD).
C-Tb; 2 T.U. Tuberculin PPD RT 23 SSI

Extrapulmonary Tuberculosis, Lymph Node Tuberculosis, or Bone Tub Clinical Trial using Positron Emission Tomography with 18F-Fluoro-deoxy-glucose

Assistance Publique - H“pitaux de Paris - Recruiting 18 years or older.
- Evaluation of Positron Emission Tomography in Extrapulmonary Tuberculosis.
Positron Emission Tomography with 18F-Fluoro-deoxy-glucose

Tuberculosis Clinical Trial using C-Tb; 2 T.U. Tuberculin PPD RT 23 SSI

Statens Serum Institut - Recruiting 6 Weeks to 65 years.
- A Phase III Contact Tracing Trial Comparing the Diagnostic Performance of C-Tb to QuantiFERONr-TB Gold In-Tube, in Combination With a Double Blind Randomized Split Body Safety Assessment of C-Tb Versus 2 T.U. Tuberculin PPD RT23 SSI.
C-Tb; 2 T.U. Tuberculin PPD RT 23 SSI

Tuberculosis Clinical Trial using DAR-901; BCG; Sterile saline

Dartmouth-Hitchcock Medical Center - Recruiting 18 years to 65 years.
- A Phase 1, Randomized, Placebo-Controlled, Double-Blind, Multiple-Dose, Dose-Ranging Study of the Safety and Immunogenicity of DAR-901, a Killed, Non-Tuberculous Mycobacterial Vaccine, in HIV-negative and HIV-positive Adults Who Have Previously Received BCG.
DAR-901; BCG; Sterile saline

Mediastinal Lymph Node Enlargement, Sarcoidosis, Tuberculosis, or Clinical Trial using EBUS guided transbronchial forceps biopsy (EBUS-TBFB); EBUS guided transbronchial needle aspiration (EBUS-TBNA); large bore (19G) histologic needle biopsy of the mediastinal lymph nodes; Bronchoalveolar lavage (BAL); Endobronchial forceps biopsy

Medical University of Warsaw - Recruiting 18 years to 80 years.
- Diagnostic Accuracy of Different Bronchoscopic Sampling Techniques in Patients With Mediastinal Lymph Node Enlargement Suspected of Sarcoidosis.
EBUS guided transbronchial forceps biopsy (EBUS-TBFB); EBUS guided transbronchial needle aspiration (EBUS-TBNA); large bore (19G) histologic needle biopsy of the mediastinal lymph nodes; Bronchoalveolar lavage (BAL); Endobronchial forceps biopsy

Active Tuberculosis Clinical Trial

Yonsei University - Recruiting 20 years to 75 years.
- Characterization and Evaluation of Diagnostic Biomarkers for Tuberculosis.

Tuberculosis Diagnosis, or HIV Clinical Trial

University of North Carolina, Chapel Hill - Recruiting N/A or older.
- CIDRZ 1201 - Optimizing Clinical Outcomes in HIV-Infected Adults & Children Using Xpert MTB/RIF in Zambia.

Active Tuberculosis Clinical Trial

Linkoeping University - Recruiting 18 years or older.
- The Role of Therapeutic Drug Monitoring in Tuberculosis - a Pilot Study.

Tuberculosis Clinical Trial using ChAdOx1 85A; MVA85A

University of Oxford - Recruiting 18 years to 55 years.
- Phase I Trial to Evaluate the Safety and Immunogenicity of a ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy BCG Vaccinated Adults.
ChAdOx1 85A; MVA85A

Tuberculosis Clinical Trial using rifapentine (M000473); EFZ EMT TDF

Sanofi - Recruiting 18 years to 55 years.
- An Open-label, Non-randomized, Single Sequence, Two Periods, Four-treatment, Three Parallel Groups Pharmacokinetic Interaction Study of Repeated Oral Doses (Daily or Weekly Regimen) of Rifapentine on ATRIPLAT (Fixed Dose Combination of Efavirenz, Emtricitabine and Tenofovir Disoproxil Fumarate) Given to HIV+ Patients.
rifapentine (M000473); EFZ EMT TDF

Tuberculosis (TB) Clinical Trial using MVA85A-IMX313; MVA85A

University of Oxford - Recruiting 18 years to 55 years.
- A Phase I Randomised Trial to Evaluate the Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in Bacille Calmette-Gu‚rin (BCG) Vaccinated Adults.
MVA85A-IMX313; MVA85A

Rheumatoid Arthritis, or Crohn's Disease Clinical Trial

UCB, Inc. - Recruiting 18 years or older.
- Observational Study to Evaluate the Safety and Effectiveness of Cimzia in Rheumatoid Arthritis and Crohn's Disease Patients When Using a Comprehensive Program of Tuberculosis Screening and Monitoring.

Pulmonary Tuberculosis Clinical Trial using Active Sodium Phenylbutyrate and active cholecalciferol; Placebo Sodium Phenylbutyrate plus active cholecalciferol; Active Sodium Phenylbutyrate and placebo cholecalciferol; Placebo Sodium Phenylbutyrate plus placebo cholecalciferol

International Centre for Diarrhoeal Disease Research, Bangladesh - Recruiting 18 years to 60 years.
- Clinical Trial of Oral Phenylbutyrate and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis in Bangladesh: a Pilot Study.
Active Sodium Phenylbutyrate and active cholecalciferol; Placebo Sodium Phenylbutyrate plus active cholecalciferol; Active Sodium Phenylbutyrate and placebo cholecalciferol; Placebo Sodium Phenylbutyrate plus placebo cholecalciferol

NSCLC Clinical Trial using Icotinib of routine dose; Icotinib of high dose

Zhejiang Beta Pharma Inc. - Recruiting 18 years to 75 years.
- An Open-label, Randomized, Multicenter, Phase II Trial to Evaluate the Safety and Efficacy of Dose Escalation of Icotinib in Advanced or Metastatic NSCLC Patients After 8 Weeks Routine Therapy Evaluated as Stable Disease.
Icotinib of routine dose; Icotinib of high dose

Tuberculosis Clinical Trial using Vaccae; placebo

Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. - Recruiting 15 years to 65 years.
- Phase III Clinical Study of Efficacy and Safety of Mycobacterium Vaccae to Prevent Tuberculosis in High Risk Groups of Tuberculosis Infection.
Vaccae; placebo

Tuberculosis Clinical Trial using GSK Biologicals' investigational TB vaccine GSK 692342; Placebo

GlaxoSmithKline - Recruiting 18 years to 59 years.
- Safety and Immunogenicity Study of GSK Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342 When Administered to Adults With TB Disease.
GSK Biologicals' investigational TB vaccine GSK 692342; Placebo

Tuberculosis, or Pulmonary Tuberculosis Clinical Trial

National Institutes of Health Clinical Center (CC) - Recruiting 20 years or older.
- A Natural History Study of Multidrug-Resistant Tuberculosis Strains and Host Susceptibility Genes in Korean Patients With Pulmonary Tuberculosis.

Latent Tuberculosis Infection, or Infection in Solid Organ Transp Clinical Trial using Levofloxacin; Isoniazid

Fundaci¢n P£blica Andaluza para la gesti¢n de la Investigaci¢n en Sevilla - Recruiting 18 years or older.
- 'A Prospective, Randomized, Comparative Clinical Trial of the Efficacy and Safety of Levofloxacin Versus Isoniazid in the Treatment of Latent Tuberculosis Infection in Liver Transplant Patients'..
Levofloxacin; Isoniazid

HIV, Tuberculosis, or Pediatric Clinical Trial using Development of a diagnosis algorithm

French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) - Recruiting N/A to 13 years.
- Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam) and Africa (Burkina Faso, Cameroon) ANRS 12229 PAANTHER 01 (Pediatric Asian African Network for Tuberculosis and HIV Research).
Development of a diagnosis algorithm

Tuberculosis Clinical Trial using Urine LAM strip test

University of Cape Town - Recruiting 18 years or older.
- A Randomized Controlled Trial to Evaluate the Impact of Using a Point-of-care Urine LAM Strip Test for TB Diagnosis Amongst Hospitalized HIV-infected Patients in Resource-poor Settings.
Urine LAM strip test

Tuberculosis Infection Clinical Trial using To confirm the potency of Aplisol formulated with newly produced Tuberculin PPD compared to PPD-S2 standard.; Reactivity of Aplisol compared to reference standard PPD-S2.

JHP Pharmaceuticals LLC - Recruiting 18 years to 60 years.
- Dose Comparison Study of Tuberculin Purified Protein Derivative (PPD)With Standard Tuberculin Purified Protein Derivative..
To confirm the potency of Aplisol formulated with newly produced Tuberculin PPD compared to PPD-S2 standard.; Reactivity of Aplisol compared to reference standard PPD-S2.

Tuberculosis Clinical Trial using Salbutamol; Sodium chloride 5%

University of Cape Town - Recruiting 12 years or older.
- Diagnostic Yield of Induced Sputum for Rapid Diagnosis of Pulmonary Tuberculosis.
Salbutamol; Sodium chloride 5%

Tuberculosis Clinical Trial

Singapore General Hospital - Recruiting 21 years or older.
- Prospective Database of All Patients With Microbiologically Proven Mycobacteria Tuberculosis Infection Treated at Singapore General Hospital.

HIV Infection, or Pulmonary TB Clinical Trial using ATT (Ethambutol, Pyrazinamide, INH, Rifampicin)

Tuberculosis Research Centre, India - Recruiting 18 years or older.
- A Randomized Controlled Clinical Trial Comparing Daily Vs. Intermittent 6 - Month Short Course Chemotherapy in Reducing Failures & Emergence of Acquired Rifampicin Resistance (ARR) in Patients With HIV and Pulmonary Tuberculosis.
ATT (Ethambutol, Pyrazinamide, INH, Rifampicin)

Non Small Cell Lung Cancer Clinical Trial using carboplatin paclitaxel bevacizumab; Standard treatment plus nitroglycerin

Dutch Society of Physicians for Pulmonology and Tuberculosis - Recruiting 18 years or older.
- A Randomized Phase II Study of Paclitaxel-carboplatin-bevacizumab With or Without Nitroglycerin Patches in Patients With Stage IV Non-squamous-non-small Cell Lung Cancer: NVALT12.
carboplatin paclitaxel bevacizumab; Standard treatment plus nitroglycerin

Latent Tuberculosis Infection Clinical Trial

Germans Trias i Pujol Hospital - Recruiting 18 years or older.
- Demonstration of the Dynamic Hypothesis of Latent Tuberculosis Infection.

Tuberculosis, or HIV Infections Clinical Trial using Emtricitabine/tenofovir/efavirenz

African Poverty Related Infection Oriented Research Initiative - Recruiting 18 years to 65 years.
- The Pharmacokinetics of Co-formulated Emtricitabine/Tenofovir/Efavirenz in HIV-infected Patients With Smear-positive Pulmonary Tuberculosis in the Kilimanjaro Region, Tanzania.
Emtricitabine/tenofovir/efavirenz

Carcinoma, Non-Small-Cell Lung Clinical Trial using erlotinib plus docetaxel or pemetrexed; erlotinib

Dutch Society of Physicians for Pulmonology and Tuberculosis - Recruiting 18 years or older.
- A Randomized Phase II Study of Erlotinib Compared to Single Agent Chemotherapy-erlotinib Combination in Pretreated Patients With Advanced NSCLC (NVALT10 Study).
erlotinib plus docetaxel or pemetrexed; erlotinib

Tuberculosis Clinical Trial

Seoul National University Hospital - Recruiting 20 years or older.
- The Impact of Vitamin D Level and Single Nucleotide Polymorphisms of Vitamin D Receptor Gene on the Development and Treatment Response of Tuberculosis.

Tuberculosis Clinical Trial

E-DA Hospital - Recruiting 18 years or older.
- Comparison of Adverse Reactions and Efficiency of Fixed-dose Combination Chemotherapy and Separate Formulations for Pulmonary Tuberculosis.

Tuberculosis, Latent Tuberculosis, Tuberculosis Contact, or Elder Clinical Trial using tuberculin for skin test

Taichung Veterans General Hospital - Recruiting N/A or older.
- Phase IV Study of the Quantiferon-RD1 Test.
tuberculin for skin test